Escherichia coli O55:K59:H is an aerobe human pathogen of the family Enterobacteriaceae.
aerobe human pathogen genome sequence Bacteria| @ref 20215 |
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Last LPSN update
2026-02-09 11:18:44 |
| Domain Bacteria |
| Phylum Pseudomonadota |
| Class Gammaproteobacteria |
| Order Enterobacterales |
| Family Enterobacteriaceae |
| Genus Escherichia |
| Species Escherichia coli |
| Full scientific name Escherichia coli (Migula 1895) Castellani and Chalmers 1919 (Approved Lists 1980) |
| Synonyms (1) |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 1820 | TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) | Medium recipe at MediaDive  | Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water | ||
| 1820 | NUTRIENT AGAR (DSMZ Medium 1) | Medium recipe at MediaDive | Name: NUTRIENT AGAR (DSMZ Medium 1) Composition: Agar 15.0 g/l Peptone 5.0 g/l Meat extract 3.0 g/l Distilled water |
| 51302 | Oxygen toleranceaerobe |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68368 | 27613 ChEBI | amygdalin | - | fermentation | from API 20E |
| 68368 | 29016 ChEBI | arginine | - | hydrolysis | from API 20E |
| 68368 | 16947 ChEBI | citrate | - | assimilation | from API 20E |
| 68368 | 17634 ChEBI | D-glucose | + | fermentation | from API 20E |
| 68368 | 16899 ChEBI | D-mannitol | + | fermentation | from API 20E |
| 68368 | 5291 ChEBI | gelatin | - | hydrolysis | from API 20E |
| 68368 | 30849 ChEBI | L-arabinose | + | fermentation | from API 20E |
| 68368 | 62345 ChEBI | L-rhamnose | - | fermentation | from API 20E |
| 68368 | 25094 ChEBI | lysine | + | degradation | from API 20E |
| 68368 | 28053 ChEBI | melibiose | + | fermentation | from API 20E |
| 68368 | 17268 ChEBI | myo-inositol | - | fermentation | from API 20E |
| 68368 | 18257 ChEBI | ornithine | - | degradation | from API 20E |
| 68368 | 30911 ChEBI | sorbitol | + | fermentation | from API 20E |
| 68368 | 17992 ChEBI | sucrose | + | fermentation | from API 20E |
| 68368 | 27897 ChEBI | tryptophan | + | energy source | from API 20E |
| 68368 | 16199 ChEBI | urea | - | hydrolysis | from API 20E |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68368 | arginine dihydrolase | - | 3.5.3.6 | from API 20E |
| 68368 | beta-galactosidase | + | 3.2.1.23 | from API 20E |
| 68368 | cytochrome oxidase | - | 1.9.3.1 | from API 20E |
| 68368 | gelatinase | - | from API 20E | |
| 68368 | lysine decarboxylase | + | 4.1.1.18 | from API 20E |
| 68368 | ornithine decarboxylase | - | 4.1.1.17 | from API 20E |
| 68368 | tryptophan deaminase | - | 4.1.99.1 | from API 20E |
| 68368 | urease | - | 3.5.1.5 | from API 20E |
| @ref | ONPG | ADH (Arg) | LDC (Lys) | ODC | CIT | H2S productionH2S | URE | TDA (Trp) | IND | Acetoin production (Voges Proskauer test)VP | GEL | GLU | MAN | INO | Sor | RHA | SAC | MEL | AMY | ARA | OX | Nitrite productionNO2 | Reduction to N2N2 | MotilityMOB | Growth on MacConkey mediumMAC | OF-O | OF-F | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1820 | + | - | + | - | - | - | - | - | + | - | - | + | + | - | + | - | + | + | - | + | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. | |
| 1820 | + | - | + | - | - | - | - | - | + | - | - | + | + | - | + | - | + | + | - | + | - | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|
| 124043 | ASM1602619v1 assembly for Escherichia coli FDAARGOS_946 | complete | GCA_016026195   | 562.68638  | 562 | 98.72 | |
| 66792 | 40961_A01 assembly for Escherichia coli NCTC9701 | contig | GCA_900449515 | 562.34261 | 562 | 79.22 | |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Metabolism | Low Endotoxin Recovery-Masking of Naturally Occurring Endotoxin. | Reich J, Weyer FA, Tamura H, Nagaoka I, Motschmann H. | Int J Mol Sci | 10.3390/ijms20040838 | 2019 | |
| Metabolism | Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serum. | Nagy ZA, Szakacs D, Boros E, Heja D, Vigh E, Sandor N, Jozsi M, Oroszlan G, Dobo J, Gal P, Pal G. | PLoS Pathog | 10.1371/journal.ppat.1008232 | 2019 | |
| Exosomal delivery of IL-10: Biodistribution, pharmacokinetics, and preterm birth prevention strategies. | Harrington B, Thomas TJ, Tatiparthy M, Kumar A, Richardson L, Menon R, Kammala AK. | Extracell Vesicle | 10.1016/j.vesic.2025.100066 | 2025 | | |
| p38 MAPK and MKP-1 control the glycolytic program via the bifunctional glycolysis regulator PFKFB3 during sepsis. | Mager CE, Mormol JM, Shelton ED, Murphy PR, Bowman BA, Barley TJ, Wang X, Linn SC, Liu K, Nelin LD, Hafner M, Liu Y. | J Biol Chem | 10.1016/j.jbc.2023.103043 | 2023 | | |
| Combination of lidocaine gel and povidone-iodine to decrease acquired infections in procedures performed using topical anesthesia. | Xia J, Lyons RJ, Lin MY, Khalifa YM, LaRock CN. | J Cataract Refract Surg | 10.1097/j.jcrs.0000000000000245 | 2020 | | |
| Metabolism | Characterization and Food Application of the Novel Lytic Phage BECP10: Specifically Recognizes the O-polysaccharide of Escherichia coli O157:H7. | Park DW, Park JH. | Viruses | 10.3390/v13081469 | 2021 | |
| Characterization of fetal microchimeric immune cells in mouse maternal hearts during physiologic and pathologic pregnancies. | Lintao RCV, Kammala AK, Radnaa E, Bettayeb M, Vincent KL, Patrikeev I, Yaklic J, Bonney EA, Menon R. | Front Cell Dev Biol | 10.3389/fcell.2023.1256945 | 2023 | | |
| Genetics | Amplification of microbial DNA from bacterial extracellular vesicles from human placenta. | Menon R, Khanipov K, Radnaa E, Ganguly E, Bento GFC, Urrabaz-Garza R, Kammala AK, Yaklic J, Pyles R, Golovko G, Tantengco OAG. | Front Microbiol | 10.3389/fmicb.2023.1213234 | 2023 | |
| A single-cell atlas of murine reproductive tissues during preterm labor. | Garcia-Flores V, Romero R, Peyvandipour A, Galaz J, Pusod E, Panaitescu B, Miller D, Xu Y, Tao L, Liu Z, Tarca AL, Pique-Regi R, Gomez-Lopez N. | Cell Rep | 10.1016/j.celrep.2022.111846 | 2023 | | |
| Metabolism | Knockout of MAPK Phosphatase-1 Exaggerates Type I IFN Response during Systemic Escherichia coli Infection. | Kirk SG, Murphy PR, Wang X, Cash CJ, Barley TJ, Bowman BA, Batty AJ, Ackerman WE, Zhang J, Nelin LD, Hafner M, Liu Y. | J Immunol | 10.4049/jimmunol.2001468 | 2021 | |
| Modeling ascending Ureaplasma parvum infection through the female reproductive tract using vagina-cervix-decidua-organ-on-a-chip and feto-maternal interface-organ-on-a-chip. | Tantengco OAG, Richardson LS, Radnaa E, Kammala AK, Kim S, Medina PMB, Han A, Menon R. | FASEB J | 10.1096/fj.202200872r | 2022 | | |
| A Novel Peptide as a Specific and Selective Probe for Klebsiella pneumoniae Detection. | Kim H, Jang JH, Jung IY, Cho JH. | Biosensors (Basel) | 10.3390/bios12030153 | 2022 | | |
| Genetics | Dynamic states of cervical epithelia during pregnancy and epithelial barrier disruption. | Cooley A, Madhukaran S, Stroebele E, Colon Caraballo M, Wang L, Akgul Y, Hon GC, Mahendroo M. | iScience | 10.1016/j.isci.2023.105953 | 2023 | |
| Host A-to-I RNA editing signatures in intracellular bacterial and single-strand RNA viral infections. | Wei ZY, Wang ZX, Li JH, Wen YS, Gao D, Xia SY, Li YN, Pan XB, Liu YS, Jin YY, Chen JH. | Front Immunol | 10.3389/fimmu.2023.1121096 | 2023 | | |
| Development of a mouse model of ascending infection and preterm birth. | Spencer NR, Radnaa E, Baljinnyam T, Kechichian T, Tantengco OAG, Bonney E, Kammala AK, Sheller-Miller S, Menon R. | PLoS One | 10.1371/journal.pone.0260370 | 2021 | | |
| Metabolism | Insight into the bovine milk peptide LPcin-YK3 selection in the proteolytic system of Lactobacillus species. | Sung WY, Yu JW, Hwang JT, Nam HJ, Park JY, Kim Y, Cho JH. | J Pept Sci | 10.1002/psc.3268 | 2020 | |
| Extraction, separation and characterization of endotoxins in water samples using solid phase extraction and capillary electrophoresis-laser induced fluorescence. | Fung FM, Su M, Feng HT, Li SFY. | Sci Rep | 10.1038/s41598-017-11232-x | 2017 | | |
| Metabolism | MKP-1 Modulates Mitochondrial Transcription Factors, Oxidative Phosphorylation, and Glycolysis. | Bauerfeld C, Talwar H, Zhang K, Liu Y, Samavati L. | Immunohorizons | 10.4049/immunohorizons.2000015 | 2020 | |
| Extracellular Vesicles-mediated recombinant IL-10 protects against ascending infection-associated preterm birth by reducing fetal inflammatory response. | Kammala AK, Mosebarger A, Radnaa E, Rowlinson E, Vora N, Fortunato SJ, Sharma S, Safarzadeh M, Menon R. | Front Immunol | 10.3389/fimmu.2023.1196453 | 2023 | | |
| Exosomes from Ureaplasma parvum-infected ectocervical epithelial cells promote feto-maternal interface inflammation but are insufficient to cause preterm delivery. | Tantengco OAG, Richardson LS, Radnaa E, Kammala AK, Kim S, Medina PMB, Han A, Menon R. | Front Cell Dev Biol | 10.3389/fcell.2022.931609 | 2022 | | |
| Pathogenicity | Intrinsic B cell TLR-BCR linked coengagement induces class-switched, hypermutated, neutralizing antibody responses in absence of T cells. | Rivera CE, Zhou Y, Chupp DP, Yan H, Fisher AD, Simon R, Zan H, Xu Z, Casali P. | Sci Adv | 10.1126/sciadv.ade8928 | 2023 | |
| Metabolism | Dysregulation of Lipid Metabolism in Mkp-1 Deficient Mice during Gram-Negative Sepsis. | Li J, Wang X, Ackerman WE, Batty AJ, Kirk SG, White WM, Wang X, Anastasakis D, Samavati L, Buhimschi I, Nelin LD, Hafner M, Liu Y. | Int J Mol Sci | 10.3390/ijms19123904 | 2018 | |
| Metabolism | Survival advantage of heterozygous factor V Leiden carriers in murine sepsis. | Kerschen E, Hernandez I, Zogg M, Maas M, Weiler H. | J Thromb Haemost | 10.1111/jth.12876 | 2015 | |
| Birth mode is associated with earliest strain-conferred gut microbiome functions and immunostimulatory potential. | Wampach L, Heintz-Buschart A, Fritz JV, Ramiro-Garcia J, Habier J, Herold M, Narayanasamy S, Kaysen A, Hogan AH, Bindl L, Bottu J, Halder R, Sjoqvist C, May P, Andersson AF, de Beaufort C, Wilmes P. | Nat Commun | 10.1038/s41467-018-07631-x | 2018 | | |
| Phylogeny | Novel single-tube agar-based test system for motility enhancement and immunocapture of Escherichia coli O157:H7 by H7 flagellar antigen-specific antibodies. | Murinda SE, Nguyen LT, Ivey SJ, Almeida RA, Oliver SP. | J Clin Microbiol | 10.1128/jcm.40.12.4685-4690.2002 | 2002 | |
| Metabolism | Myeloid-Specific Gene Deletion of Protein Phosphatase 2A Magnifies MyD88- and TRIF-Dependent Inflammation following Endotoxin Challenge. | Sun L, Pham TT, Cornell TT, McDonough KL, McHugh WM, Blatt NB, Dahmer MK, Shanley TP. | J Immunol | 10.4049/jimmunol.1600221 | 2017 | |
| Effect of flash-heat treatment on antimicrobial activity of breastmilk. | Chantry CJ, Wiedeman J, Buehring G, Peerson JM, Hayfron K, K'Aluoch O, Lonnerdal B, Israel-Ballard K, Coutsoudis A, Abrams B. | Breastfeed Med | 10.1089/bfm.2010.0078 | 2011 | | |
| Enzymology | High diversity among environmental Escherichia coli isolates from a bovine feedlot. | Yang HH, Vinopal RT, Grasso D, Smets BF. | Appl Environ Microbiol | 10.1128/aem.70.3.1528-1536.2004 | 2004 | |
| Metabolism | Differences in release of tumor necrosis factor from THP-1 cells stimulated by filtrates of antibiotic-killed Escherichia coli. | Simon DM, Koenig G, Trenholme GM. | J Infect Dis | 10.1093/infdis/164.4.800 | 1991 | |
| Interferon-gamma production by neutrophils during bacterial pneumonia in mice. | Yamada M, Gomez JC, Chugh PE, Lowell CA, Dinauer MC, Dittmer DP, Doerschuk CM. | Am J Respir Crit Care Med | 10.1164/rccm.201004-0592oc | 2011 | | |
| Metabolism | Clindamycin suppresses endotoxin released by ceftazidime-treated Escherichia coli O55:B5 and subsequent production of tumor necrosis factor alpha and interleukin-1 beta. | Kishi K, Hirai K, Hiramatsu K, Yamasaki T, Nasu M. | Antimicrob Agents Chemother | 10.1128/aac.43.3.616 | 1999 | |
| Pathogenicity | Antibacterial activities and characterization of novel inhibitors of LpxC. | Clements JM, Coignard F, Johnson I, Chandler S, Palan S, Waller A, Wijkmans J, Hunter MG. | Antimicrob Agents Chemother | 10.1128/aac.46.6.1793-1799.2002 | 2002 | |
| A randomized controlled trial of interleukin-1 receptor antagonist in a rabbit model of ascending infection in pregnancy. | McDuffie RS, Davies JK, Leslie KK, Lee S, Sherman MP, Gibbs RS. | Infect Dis Obstet Gynecol | 10.1155/s1064744901000382 | 2001 | | |
| Standard requirement of a microbiological quality control program for the manufacture of human mesenchymal stem cells for clinical use. | Galvez P, Clares B, Bermejo M, Hmadcha A, Soria B. | Stem Cells Dev | 10.1089/scd.2013.0625 | 2014 | | |
| Pathogenicity | Antimicrobial and membrane disrupting activities of a peptide derived from the human cathelicidin antimicrobial peptide LL37. | Thennarasu S, Tan A, Penumatchu R, Shelburne CE, Heyl DL, Ramamoorthy A. | Biophys J | 10.1016/j.bpj.2009.09.060 | 2010 | |
| Metabolism | Increased inflammation, impaired bacterial clearance, and metabolic disruption after gram-negative sepsis in Mkp-1-deficient mice. | Frazier WJ, Wang X, Wancket LM, Li XA, Meng X, Nelin LD, Cato AC, Liu Y. | J Immunol | 10.4049/jimmunol.0804343 | 2009 | |
| Metabolism | Glutathione reductase facilitates host defense by sustaining phagocytic oxidative burst and promoting the development of neutrophil extracellular traps. | Yan J, Meng X, Wancket LM, Lintner K, Nelin LD, Chen B, Francis KP, Smith CV, Rogers LK, Liu Y. | J Immunol | 10.4049/jimmunol.1102683 | 2012 | |
| In vitro bacterial contamination of amniotic fluid: effects on fluorescence polarization lung maturity testing. | Heine RP, Harding S, Emmett P, Ashwood E, Lenke RR. | Infect Dis Obstet Gynecol | 10.1155/s1064744995000408 | 1995 | | |
| Failure of E. coli bacteria to induce preterm delivery in the rat. | Hirsch E, Filipovich Y, Romero R. | J Negat Results Biomed | 10.1186/1477-5751-8-1 | 2009 | | |
| Metabolism | The rfaS gene, which is involved in production of a rough form of lipopolysaccharide core in Escherichia coli K-12, is not present in the rfa cluster of Salmonella typhimurium LT2. | Klena JD, Pradel E, Schnaitman CA. | J Bacteriol | 10.1128/jb.175.5.1524-1527.1993 | 1993 | |
| Specimen housing unit for cinemicrographic studies in the vertical plane. | Wilkins JR, Tynan CI, Boykin EH. | Appl Environ Microbiol | 10.1128/aem.32.2.294-297.1976 | 1976 | | |
| Metabolism | Deletion of all cysteines in tachyplesin I abolishes hemolytic activity and retains antimicrobial activity and lipopolysaccharide selective binding. | Ramamoorthy A, Thennarasu S, Tan A, Gottipati K, Sreekumar S, Heyl DL, An FY, Shelburne CE. | Biochemistry | 10.1021/bi052629q | 2006 | |
| Phylogeny | Rapid multiplex assay for serotyping pneumococci with monoclonal and polyclonal antibodies. | Yu J, Lin J, Benjamin WH, Waites KB, Lee CH, Nahm MH. | J Clin Microbiol | 10.1128/jcm.43.1.156-162.2005 | 2005 | |
| Infection and immunoglobulin concentrations in Chediak-Higashi mice. | Elin RJ, Edelin JB, Wolff SM. | Infect Immun | 10.1128/iai.10.1.88-91.1974 | 1974 | | |
| Isolation and characterization of murine monoclonal antibodies specific for gram-negative bacterial lipopolysaccharide: association of cross-genus reactivity with lipid A specificity. | Bogard WC, Dunn DL, Abernethy K, Kilgarriff C, Kung PC. | Infect Immun | 10.1128/iai.55.4.899-908.1987 | 1987 | | |
| Outer membrane proteins of Escherichia coli. IV. Differences in outer membrane proteins due to strain and cultural differences. | Schnaitman CA. | J Bacteriol | 10.1128/jb.118.2.454-464.1974 | 1974 | | |
| A porous cervical mucus plug leads to preterm birth induced by experimental vaginal infection in mice. | Lacroix G, Gouyer V, Rocher M, Gottrand F, Desseyn JL. | iScience | 10.1016/j.isci.2022.104526 | 2022 | | |
| A test for the assessment of disinfectant/sanitizers used for napkin storage. | Prosser-Snelling KR, Duke AM, Rodger MN. | J Hyg (Lond) | 10.1017/s0022172400053146 | 1977 | | |
| Flagellum-Mediated Mechanosensing and RflP Control Motility State of Pathogenic Escherichia coli. | Laganenka L, Lopez ME, Colin R, Sourjik V. | mBio | 10.1128/mbio.02269-19 | 2020 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive4516.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
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