Escherichia coli BW25113 is a human pathogen of the family Enterobacteriaceae.
human pathogen genome sequence| @ref 20215 |
|
|
| Domain Bacteria |
| Phylum Pseudomonadota |
| Class Gammaproteobacteria |
| Order Enterobacterales |
| Family Enterobacteriaceae |
| Genus Escherichia |
| Species Escherichia coli |
| Full scientific name Escherichia coli (Migula 1895) Castellani and Chalmers 1919 (Approved Lists 1980) |
| Synonyms (1) |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 42350 | LB (Luria-Bertani) MEDIUM (DSMZ Medium 381) | Medium recipe at MediaDive | Name: LB (Luria-Bertani) MEDIUM (DSMZ Medium 381) Composition: Agar 20.0 g/l NaCl 10.0 g/l Tryptone 10.0 g/l Yeast extract 5.0 g/l Distilled water |
| @ref | Growth | Type | Temperature (°C) | |
|---|---|---|---|---|
| 42350 | positive | growth | 30 |
| @ref | Oxygen tolerance | Confidence | |
|---|---|---|---|
| 125439 | obligate aerobe | 96.3 |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68368 | 27613 ChEBI | amygdalin | - | fermentation | from API 20E |
| 68368 | 29016 ChEBI | arginine | - | hydrolysis | from API 20E |
| 68368 | 16947 ChEBI | citrate | - | assimilation | from API 20E |
| 68368 | 17634 ChEBI | D-glucose | + | fermentation | from API 20E |
| 68368 | 16899 ChEBI | D-mannitol | + | fermentation | from API 20E |
| 68368 | 5291 ChEBI | gelatin | - | hydrolysis | from API 20E |
| 68368 | 30849 ChEBI | L-arabinose | - | fermentation | from API 20E |
| 68368 | 62345 ChEBI | L-rhamnose | - | fermentation | from API 20E |
| 68368 | 25094 ChEBI | lysine | + | degradation | from API 20E |
| 68368 | 28053 ChEBI | melibiose | + | fermentation | from API 20E |
| 68368 | 17268 ChEBI | myo-inositol | - | fermentation | from API 20E |
| 68368 | 18257 ChEBI | ornithine | - | degradation | from API 20E |
| 68368 | 30911 ChEBI | sorbitol | + | fermentation | from API 20E |
| 68368 | 17992 ChEBI | sucrose | - | fermentation | from API 20E |
| 68368 | 27897 ChEBI | tryptophan | + | energy source | from API 20E |
| 68368 | 16199 ChEBI | urea | - | hydrolysis | from API 20E |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68368 | arginine dihydrolase | - | 3.5.3.6 | from API 20E |
| 68368 | beta-galactosidase | - | 3.2.1.23 | from API 20E |
| 68368 | cytochrome oxidase | - | 1.9.3.1 | from API 20E |
| 68368 | gelatinase | - | from API 20E | |
| 68368 | lysine decarboxylase | + | 4.1.1.18 | from API 20E |
| 68368 | ornithine decarboxylase | - | 4.1.1.17 | from API 20E |
| 68368 | tryptophan deaminase | - | 4.1.99.1 | from API 20E |
| 68368 | urease | - | 3.5.1.5 | from API 20E |
| @ref | ONPG | ADH (Arg) | LDC (Lys) | ODC | CIT | H2S productionH2S | URE | TDA (Trp) | IND | Acetoin production (Voges Proskauer test)VP | GEL | GLU | MAN | INO | Sor | RHA | SAC | MEL | AMY | ARA | OX | Nitrite productionNO2 | Reduction to N2N2 | MotilityMOB | Growth on MacConkey mediumMAC | OF-O | OF-F | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 42350 | - | - | + | - | - | - | - | - | + | - | - | + | + | - | + | - | - | + | - | - | - | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. |
| @ref | Pathogenicity human | Pathogenicity animal | Biosafety level | Biosafety level comment | |
|---|---|---|---|---|---|
| 42350 | 1 | Risk group (German classification) |
| @ref | Trait | Model | Prediction | Confidence in % | In training data |
|---|---|---|---|---|---|
| 125439 | spore_formation | BacteriaNetⓘ | no | 89.20 | no |
| 125439 | motility | BacteriaNetⓘ | yes | 64.90 | no |
| 125439 | gram_stain | BacteriaNetⓘ | negative | 91.10 | no |
| 125439 | oxygen_tolerance | BacteriaNetⓘ | obligate aerobe | 96.30 | no |
| @ref | Trait | Model | Prediction | Confidence in % | In training data |
|---|---|---|---|---|---|
| 125438 | gram-positive | gram-positiveⓘ | no | 99.75 | no |
| 125438 | anaerobic | anaerobicⓘ | no | 95.78 | no |
| 125438 | spore-forming | spore-formingⓘ | no | 87.95 | no |
| 125438 | aerobic | aerobicⓘ | no | 60.25 | no |
| 125438 | thermophilic | thermophileⓘ | no | 98.50 | no |
| 125438 | flagellated | motile2+ⓘ | yes | 75.36 | no |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Metabolism | Genome-Guided Discovery of the First Myxobacterial Biarylitide Myxarylin Reveals Distinct C-N Biaryl Crosslinking in RiPP Biosynthesis. | Hug JJ, Frank NA, Walt C, Senica P, Panter F, Muller R. | Molecules | 10.3390/molecules26247483 | 2021 | |
| Metabolism | SIMMER employs similarity algorithms to accurately identify human gut microbiome species and enzymes capable of known chemical transformations. | Bustion AE, Nayak RR, Agrawal A, Turnbaugh PJ, Pollard KS. | Elife | 10.7554/elife.82401 | 2023 | |
| Metabolism | Methotrexate impacts conserved pathways in diverse human gut bacteria leading to decreased host immune activation. | Nayak RR, Alexander M, Deshpande I, Stapleton-Gray K, Rimal B, Patterson AD, Ubeda C, Scher JU, Turnbaugh PJ. | Cell Host Microbe | 10.1016/j.chom.2020.12.008 | 2021 | |
| Protocol to detect dilution cycles in chemostat experiments and estimate growth rate slopes with linear modeling with R software chemostat_regression. | Koehler SI, Pentz JT, Middlebrook EA, Hovde BT, Hanschen ER. | STAR Protoc | 10.1016/j.xpro.2025.104113 | 2025 | ||
| Cyclic di-GMP as an antitoxin regulates bacterial genome stability and antibiotic persistence in biofilms. | Liao H, Yan X, Wang C, Huang C, Zhang W, Xiao L, Jiang J, Bao Y, Huang T, Zhang H, Guo C, Zhang Y, Pu Y. | Elife | 10.7554/elife.99194 | 2024 | ||
| Persistence and Culturability of Escherichia coli under Induced Toxin Expression. | Dhaouadi Y, Hashemi MJ, Ren D. | Antibiotics (Basel) | 10.3390/antibiotics13090863 | 2024 | ||
| A tradeoff between bacteriophage resistance and bacterial motility is mediated by the Rcs phosphorelay in Escherichia coli. | Burmeister AR, Tewatia H, Skinner C. | Microbiology (Reading) | 10.1099/mic.0.001491 | 2024 | ||
| Mapping protein-metabolite interactions in E. coli by integrating chromatographic techniques and co-fractionation mass spectrometry. | Wagner M, Kang J, Mercado C, Thirumlaikumar VP, Gorka M, Zillmer H, Guo J, Minen RI, Plecki CF, Dehesh K, Schroeder FC, Walther D, Skirycz A. | iScience | 10.1016/j.isci.2025.112611 | 2025 | ||
| Fluorescence-based protocol for revealing cellular arrangement in biofilms. | Puri D, Fang X, Allison KR. | STAR Protoc | 10.1016/j.xpro.2023.102270 | 2023 | ||
| Metabolism | Absolute requirement for polyamines for growth of Escherichia coli mutants (mnmE/G) defective in modification of the wobble anticodon of transfer-RNA. | Keller C, Chattopadhyay M, Tabor H. | FEMS Microbiol Lett | 10.1093/femsle/fnz110 | 2019 | |
| Exploration of the Fusidic Acid Structure Activity Space for Antibiotic Activity. | Kang YS, Silva SC, Smith K, Sumida K, Wang Y, Chiaraviglio L, Donthiri RR, Aljahdali AZ, Kirby JE, O'Doherty GA. | Molecules | 10.3390/molecules30030465 | 2025 | ||
| Metabolism | Bacterial Methionine Metabolism Genes Influence Drosophila melanogaster Starvation Resistance. | Judd AM, Matthews MK, Hughes R, Veloz M, Sexton CE, Chaston JM. | Appl Environ Microbiol | 10.1128/aem.00662-18 | 2018 | |
| Characterization of Bacterial Transcriptional Regulatory Networks in Escherichia coli through Genome-Wide In Vitro Run-Off Transcription/RNA-seq (ROSE). | Schmidt P, Brandt D, Busche T, Kalinowski J. | Microorganisms | 10.3390/microorganisms11061388 | 2023 | ||
| Genetics | Genetic Influences of the Microbiota on the Life Span of Drosophila melanogaster. | Matthews MK, Wilcox H, Hughes R, Veloz M, Hammer A, Banks B, Walters A, Schneider KJ, Sexton CE, Chaston JM. | Appl Environ Microbiol | 10.1128/aem.00305-20 | 2020 | |
| The antibacterial activity of a photoactivatable diarylacetylene against Gram-positive bacteria. | Waite R, Adams CT, Chisholm DR, Sims CHC, Hughes JG, Dias E, White EA, Welsby K, Botchway SW, Whiting A, Sharples GJ, Ambler CA. | Front Microbiol | 10.3389/fmicb.2023.1243818 | 2023 | ||
| Light-dependent modulation of protein localization and function in living bacteria cells. | McQuillen R, Perez AJ, Yang X, Bohrer CH, Smith EL, Chareyre S, Tsui HT, Bruce KE, Hla YM, McCausland JW, Winkler ME, Goley ED, Ramamurthi KS, Xiao J. | Nat Commun | 10.1038/s41467-024-54974-9 | 2024 | ||
| Copper and nanostructured anatase rutile and carbon coatings induce adaptive antibiotic resistance. | Wasa A, Aitken J, Jun H, Bishop C, Krumdieck S, Godsoe W, Heinemann JA. | AMB Express | 10.1186/s13568-022-01457-z | 2022 | ||
| Metabolism | Characterization of MenA (isoprenyl diphosphate:1,4-dihydroxy-2-naphthoate isoprenyltransferase) from Mycobacterium tuberculosis. | Dhiman RK, Pujari V, Kincaid JM, Ikeh MA, Parish T, Crick DC. | PLoS One | 10.1371/journal.pone.0214958 | 2019 | |
| Relative impact of three growth conditions on the Escherichia coli protein acetylome. | Lozano-Terol G, Chiozzi RZ, Gallego-Jara J, Sola-Martinez RA, Vivancos AM, Ortega A, Heck AJR, Diaz MC, de Diego Puente T. | iScience | 10.1016/j.isci.2024.109017 | 2024 | ||
| Boron-Containing Analogs of Fosmidomycin: Benzoxaborole Derivatives Exhibit Promising Activity Against Resistant Pathogens. | Gamrat JM, Orme CL, Mancini G, Burke SJ, Alhthlol LM, Colandrea RC, Figula BC, Tomares DT, Heindl JE, Tomsho JW. | ACS Omega | 10.1021/acsomega.5c02701 | 2025 | ||
| Tuning interdomain conjugation to enable in situ population modification in yeasts. | Stindt KR, McClean MN. | mSystems | 10.1128/msystems.00050-24 | 2024 | ||
| Reciprocal Packaging of the Main Structural Proteins of Type 1 Fimbriae and Flagella in the Outer Membrane Vesicles of "Wild Type" Escherichia coli Strains. | Blackburn SA, Shepherd M, Robinson GK. | Front Microbiol | 10.3389/fmicb.2021.557455 | 2021 | ||
| Genetics | Genome integrity sensing by the broad-spectrum Hachiman antiphage defense complex. | Tuck OT, Adler BA, Armbruster EG, Lahiri A, Hu JJ, Zhou J, Pogliano J, Doudna JA. | Cell | 10.1016/j.cell.2024.09.020 | 2024 | |
| Evidence of a possible multicellular life cycle in Escherichia coli. | Puri D, Fang X, Allison KR. | iScience | 10.1016/j.isci.2022.105795 | 2023 | ||
| Genetics | Coupling between DNA replication, segregation, and the onset of constriction in Escherichia coli. | Tiruvadi-Krishnan S, Mannik J, Kar P, Lin J, Amir A, Mannik J. | Cell Rep | 10.1016/j.celrep.2022.110539 | 2022 | |
| Metabolism | Reactive metabolic byproducts contribute to antibiotic lethality under anaerobic conditions. | Wong F, Stokes JM, Bening SC, Vidoudez C, Trauger SA, Collins JJ. | Mol Cell | 10.1016/j.molcel.2022.07.009 | 2022 | |
| Stimuli-responsive vesicles as distributed artificial organelles for bacterial activation. | Gispert I, Hindley JW, Pilkington CP, Shree H, Barter LMC, Ces O, Elani Y. | Proc Natl Acad Sci U S A | 10.1073/pnas.2206563119 | 2022 | ||
| tRNA methylation resolves codon usage bias at the limit of cell viability. | Masuda I, Yamaki Y, Detroja R, Tagore S, Moore H, Maharjan S, Nakano Y, Christian T, Matsubara R, Lowe TM, Frenkel-Morgenstern M, Hou YM. | Cell Rep | 10.1016/j.celrep.2022.111539 | 2022 | ||
| Pathogenicity | Genomewide screen for modulators of evolvability under toxic antibiotic exposure. | Mehi O, Bogos B, Csorgo B, Pal C. | Antimicrob Agents Chemother | 10.1128/aac.02454-12 | 2013 | |
| Phylogeny | Microbiota Influences Fitness and Timing of Reproduction in the Fruit Fly Drosophila melanogaster. | Matthews MK, Malcolm J, Chaston JM. | Microbiol Spectr | 10.1128/spectrum.00034-21 | 2021 | |
| Metabolism | Conversion of Escherichia coli to Generate All Biomass Carbon from CO2. | Gleizer S, Ben-Nissan R, Bar-On YM, Antonovsky N, Noor E, Zohar Y, Jona G, Krieger E, Shamshoum M, Bar-Even A, Milo R. | Cell | 10.1016/j.cell.2019.11.009 | 2019 | |
| Serine Protease Networks Mediate Immune Responses in Extra-Embryonic Tissues of Eggs in the Tobacco Hornworm, Manduca sexta. | Shan T, Wang Y, Dittmer NT, Kanost MR, Jiang H. | J Innate Immun | 10.1159/000527974 | 2023 | ||
| Synthesis and Antimicrobial Evaluation of gamma-Borono Phosphonate Compounds in Escherichia coli and Mycobacterium smegmatis. | Mancini G, Bouda M, Gamrat JM, Tomsho JW. | ACS Omega | 10.1021/acsomega.9b01774 | 2019 | ||
| Metabolism | Synthetic Whole-Cell Biodevices for Targeted Degradation of Antibiotics. | Xia PF, Li Q, Tan LR, Liu MM, Jin YS, Wang SG. | Sci Rep | 10.1038/s41598-018-21350-9 | 2018 | |
| Dictyostelium discoideum cells retain nutrients when the cells are about to outgrow their food source. | Rijal R, Kirolos SA, Rahman RJ, Gomer RH. | J Cell Sci | 10.1242/jcs.260107 | 2022 | ||
| Metabolism | Comparison of engineered Escherichia coli AF1000 and BL21 strains for (R)-3-hydroxybutyrate production in fed-batch cultivation. | Perez-Zabaleta M, Guevara-Martinez M, Gustavsson M, Quillaguaman J, Larsson G, van Maris AJA. | Appl Microbiol Biotechnol | 10.1007/s00253-019-09876-y | 2019 | |
| The Copper Efflux Regulator CueR Is Subject to ATP-Dependent Proteolysis in Escherichia coli. | Bittner LM, Kraus A, Schakermann S, Narberhaus F. | Front Mol Biosci | 10.3389/fmolb.2017.00009 | 2017 | ||
| Pathogenicity | Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps. | Ple C, Tam HK, Vieira Da Cruz A, Compagne N, Jimenez-Castellanos JC, Muller RT, Pradel E, Foong WE, Malloci G, Ballee A, Kirchner MA, Moshfegh P, Herledan A, Herrmann A, Deprez B, Willand N, Vargiu AV, Pos KM, Flipo M, Hartkoorn RC. | Nat Commun | 10.1038/s41467-021-27726-2 | 2022 | |
| Pathogenicity | Escherichia coli vectors having stringently repressible replication origins allow a streamlining of Crispr/Cas9 gene editing. | Srinivas S, Hu Z, Cronan JE. | Plasmid | 10.1016/j.plasmid.2019.04.004 | 2019 | |
| The Role of Outer Membrane Proteins and Lipopolysaccharides for the Sensitivity of Escherichia coli to Antimicrobial Peptides. | Ebbensgaard A, Mordhorst H, Aarestrup FM, Hansen EB. | Front Microbiol | 10.3389/fmicb.2018.02153 | 2018 | ||
| Metabolism | Systematic identification of metabolites controlling gene expression in E. coli. | Lempp M, Farke N, Kuntz M, Freibert SA, Lill R, Link H. | Nat Commun | 10.1038/s41467-019-12474-1 | 2019 | |
| Metabolism | AraBAD Based Toolkit for Gene Expression and Metabolic Robustness Improvement in Synechococcus elongatus. | Cao YQ, Li Q, Xia PF, Wei LJ, Guo N, Li JW, Wang SG. | Sci Rep | 10.1038/s41598-017-17035-4 | 2017 | |
| Metabolism | Polyphosphate is an extracellular signal that can facilitate bacterial survival in eukaryotic cells. | Rijal R, Cadena LA, Smith MR, Carr JF, Gomer RH. | Proc Natl Acad Sci U S A | 10.1073/pnas.2012009117 | 2020 | |
| Pathogenicity | Membrane voltage dysregulation driven by metabolic dysfunction underlies bactericidal activity of aminoglycosides. | Bruni GN, Kralj JM. | Elife | 10.7554/elife.58706 | 2020 | |
| Enzymology | Discovery of a Kojibiose Phosphorylase in Escherichia coli K-12. | Mukherjee K, Narindoshvili T, Raushel FM. | Biochemistry | 10.1021/acs.biochem.8b00392 | 2018 | |
| Metabolism | Cellular Stress Upregulates Indole Signaling Metabolites in Escherichia coli. | Kim CS, Li JH, Barco B, Park HB, Gatsios A, Damania A, Wang R, Wyche TP, Piizzi G, Clay NK, Crawford JM. | Cell Chem Biol | 10.1016/j.chembiol.2020.03.003 | 2020 | |
| Pathogenicity | Programmable CRISPR-Cas transcriptional activation in bacteria. | Ho HI, Fang JR, Cheung J, Wang HH. | Mol Syst Biol | 10.15252/msb.20199427 | 2020 | |
| Pyrrolomycins Are Potent Natural Protonophores. | Valderrama K, Pradel E, Firsov AM, Drobecq H, Bauderlique-le Roy H, Villemagne B, Antonenko YN, Hartkoorn RC. | Antimicrob Agents Chemother | 10.1128/aac.01450-19 | 2019 | ||
| Metabolism | Metabolic phospholipid labeling of intact bacteria enables a fluorescence assay that detects compromised outer membranes. | Nilsson I, Lee SY, Sawyer WS, Baxter Rath CM, Lapointe G, Six DA. | J Lipid Res | 10.1194/jlr.ra120000654 | 2020 | |
| Metabolism | Ribosomal elongation factor 4 promotes cell death associated with lethal stress. | Li L, Hong Y, Luan G, Mosel M, Malik M, Drlica K, Zhao X. | mBio | 10.1128/mbio.01708-14 | 2014 | |
| Metabolism | Epistatic Interactions in the Arabinose Cis-Regulatory Element. | Lagator M, Igler C, Moreno AB, Guet CC, Bollback JP. | Mol Biol Evol | 10.1093/molbev/msv269 | 2016 | |
| Metabolism | tRNA Methylation Is a Global Determinant of Bacterial Multi-drug Resistance. | Masuda I, Matsubara R, Christian T, Rojas ER, Yadavalli SS, Zhang L, Goulian M, Foster LJ, Huang KC, Hou YM. | Cell Syst | 10.1016/j.cels.2019.03.008 | 2019 | |
| Next-Generation Sequencing-Based RiboMethSeq Protocol for Analysis of tRNA 2'-O-Methylation. | Marchand V, Pichot F, Thuring K, Ayadi L, Freund I, Dalpke A, Helm M, Motorin Y. | Biomolecules | 10.3390/biom7010013 | 2017 | ||
| Metabolism | Engineered Production of Short Chain Fatty Acid in Escherichia coli Using Fatty Acid Synthesis Pathway. | Jawed K, Mattam AJ, Fatma Z, Wajid S, Abdin MZ, Yazdani SS. | PLoS One | 10.1371/journal.pone.0160035 | 2016 | |
| Elucidation of the co-metabolism of glycerol and glucose in Escherichia coli by genetic engineering, transcription profiling, and (13)C metabolic flux analysis. | Yao R, Xiong D, Hu H, Wakayama M, Yu W, Zhang X, Shimizu K. | Biotechnol Biofuels | 10.1186/s13068-016-0591-1 | 2016 | ||
| Metabolism | Release of extracellular ATP by bacteria during growth. | Mempin R, Tran H, Chen C, Gong H, Kim Ho K, Lu S. | BMC Microbiol | 10.1186/1471-2180-13-301 | 2013 | |
| Pathogenicity | Lethal synergy involving bicyclomycin: an approach for reviving old antibiotics. | Malik M, Li L, Zhao X, Kerns RJ, Berger JM, Drlica K. | J Antimicrob Chemother | 10.1093/jac/dku285 | 2014 | |
| Pathogenicity | Inhibition of Bacterial Gene Transcription with an RpoN-Based Stapled Peptide. | Payne SR, Pau DI, Whiting AL, Kim YJ, Pharoah BM, Moi C, Boddy CN, Bernal F. | Cell Chem Biol | 10.1016/j.chembiol.2018.05.007 | 2018 | |
| Metabolism | A gut microbial factor modulates locomotor behaviour in Drosophila. | Schretter CE, Vielmetter J, Bartos I, Marka Z, Marka S, Argade S, Mazmanian SK. | Nature | 10.1038/s41586-018-0634-9 | 2018 | |
| Engineering E. coli strain for conversion of short chain fatty acids to bioalcohols. | Mattam AJ, Yazdani SS. | Biotechnol Biofuels | 10.1186/1754-6834-6-128 | 2013 | ||
| Pathogenicity | Nitrothiophene carboxamides, a novel narrow spectrum antibacterial series: Mechanism of action and Efficacy. | Hameed P S, Bharatham N, Katagihallimath N, Sharma S, Nandishaiah R, Shanbhag AP, Thomas T, Narjari R, Sarma M, Bhowmik P, Amar P, Ravishankar R, Jayaraman R, Muthan K, Subbiah R, Ramachandran V, Balasubramanian V, Datta S. | Sci Rep | 10.1038/s41598-018-25407-7 | 2018 | |
| Metabolism | The 2'-O-methylation status of a single guanosine controls transfer RNA-mediated Toll-like receptor 7 activation or inhibition. | Jockel S, Nees G, Sommer R, Zhao Y, Cherkasov D, Hori H, Ehm G, Schnare M, Nain M, Kaufmann A, Bauer S. | J Exp Med | 10.1084/jem.20111075 | 2012 | |
| Near-Infrared Fluorescent Proteins Engineered from Bacterial Phytochromes in Neuroimaging. | Piatkevich KD, Suk HJ, Kodandaramaiah SB, Yoshida F, DeGennaro EM, Drobizhev M, Hughes TE, Desimone R, Boyden ES, Verkhusha VV. | Biophys J | 10.1016/j.bpj.2017.09.007 | 2017 | ||
| Metabolism | Dissipation of proton motive force is not sufficient to induce the phage shock protein response in Escherichia coli. | Engl C, Beek AT, Bekker M, de Mattos JT, Jovanovic G, Buck M. | Curr Microbiol | 10.1007/s00284-011-9869-5 | 2011 | |
| Pathogenicity | Contribution of oxidative damage to antimicrobial lethality. | Wang X, Zhao X. | Antimicrob Agents Chemother | 10.1128/aac.01087-08 | 2009 | |
| A Deep Learning Approach to Antibiotic Discovery. | Stokes JM, Yang K, Swanson K, Jin W, Cubillos-Ruiz A, Donghia NM, MacNair CR, French S, Carfrae LA, Bloom-Ackermann Z, Tran VM, Chiappino-Pepe A, Badran AH, Andrews IW, Chory EJ, Church GM, Brown ED, Jaakkola TS, Barzilay R, Collins JJ. | Cell | 10.1016/j.cell.2020.01.021 | 2020 | ||
| Metabolism | A Multiplex Enzymatic Machinery for Cellular Protein S-nitrosylation. | Seth D, Hess DT, Hausladen A, Wang L, Wang YJ, Stamler JS. | Mol Cell | 10.1016/j.molcel.2017.12.025 | 2018 | |
| Changes in the genetic requirements for microbial interactions with increasing community complexity. | Morin M, Pierce EC, Dutton RJ. | Elife | 10.7554/elife.37072 | 2018 | ||
| Metabolism | PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin. | Gust B, Challis GL, Fowler K, Kieser T, Chater KF. | Proc Natl Acad Sci U S A | 10.1073/pnas.0337542100 | 2003 | |
| Metabolism | The biochemical origins of the surface-enhanced Raman spectra of bacteria: a metabolomics profiling by SERS. | Premasiri WR, Lee JC, Sauer-Budge A, Theberge R, Costello CE, Ziegler LD. | Anal Bioanal Chem | 10.1007/s00216-016-9540-x | 2016 | |
| Metabolism | Host-Microbe Co-metabolism Dictates Cancer Drug Efficacy in C. elegans. | Scott TA, Quintaneiro LM, Norvaisas P, Lui PP, Wilson MP, Leung KY, Herrera-Dominguez L, Sudiwala S, Pessia A, Clayton PT, Bryson K, Velagapudi V, Mills PB, Typas A, Greene NDE, Cabreiro F. | Cell | 10.1016/j.cell.2017.03.040 | 2017 | |
| How Obstacles Perturb Population Fronts and Alter Their Genetic Structure. | Mobius W, Murray AW, Nelson DR. | PLoS Comput Biol | 10.1371/journal.pcbi.1004615 | 2015 | ||
| Stress | Optimization of a one-step heat-inducible in vivo mini DNA vector production system. | Nafissi N, Sum CH, Wettig S, Slavcev RA. | PLoS One | 10.1371/journal.pone.0089345 | 2014 | |
| Promoter activation by CII, a potent transcriptional activator from bacteriophage 186. | Murchland I, Ahlgren-Berg A, Priest DG, Dodd IB, Shearwin KE. | J Biol Chem | 10.1074/jbc.m114.608026 | 2014 |
| #20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 ) |
| #42350 | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 27469 |
| #66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) . |
| #68368 | Automatically annotated from API 20E . |
| #124042 | Johannes Wittmann, Clara Rolland, Lorenz Reimer, Joaquim Sardà: PhageDive . |
| #124043 | Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy . |
| #125438 | Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 ) |
| #125439 | Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 . |
| #126262 | A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 ) |
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