Staphylococcus aureus RN4220 is a mesophilic human pathogen that was isolated from laboratory research strain originally derived from NCTC 8325-4 using UV and chemical mutagenesis.
mesophilic human pathogen genome sequence| @ref 20215 |
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| Domain Bacillati |
| Phylum Bacillota |
| Class Bacilli |
| Order Caryophanales |
| Family Staphylococcaceae |
| Genus Staphylococcus |
| Species Staphylococcus aureus |
| Full scientific name Staphylococcus aureus Rosenbach 1884 (Approved Lists 1980) |
| Synonyms (2) |
| @ref | Gram stain | Confidence | |
|---|---|---|---|
| 125439 | positive | 96.6 |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 18922 | TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) | Medium recipe at MediaDive | Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water |
| @ref | Growth | Type | Temperature (°C) | Range | |
|---|---|---|---|---|---|
| 18922 | positive | growth | 37 | mesophilic |
| @ref | Oxygen tolerance | Confidence | |
|---|---|---|---|
| 125439 | facultative anaerobe | 94.6 |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68375 | 22599 ChEBI | arabinose | - | fermentation | from API ID32STA |
| 68375 | 29016 ChEBI | arginine | + | hydrolysis | from API ID32STA |
| 68375 | 17057 ChEBI | cellobiose | - | fermentation | from API ID32STA |
| 68375 | 15824 ChEBI | D-fructose | + | fermentation | from API ID32STA |
| 68375 | 17634 ChEBI | D-glucose | + | fermentation | from API ID32STA |
| 68375 | 16899 ChEBI | D-mannitol | + | fermentation | from API ID32STA |
| 68375 | 16024 ChEBI | D-mannose | + | fermentation | from API ID32STA |
| 68375 | 16988 ChEBI | D-ribose | - | fermentation | from API ID32STA |
| 68375 | 4853 ChEBI | esculin | - | hydrolysis | from API ID32STA |
| 68375 | 17716 ChEBI | lactose | + | fermentation | from API ID32STA |
| 68375 | 17306 ChEBI | maltose | + | fermentation | from API ID32STA |
| 68375 | 59640 ChEBI | N-acetylglucosamine | + | fermentation | from API ID32STA |
| 68375 | 17632 ChEBI | nitrate | + | reduction | from API ID32STA |
| 68375 | 18257 ChEBI | ornithine | - | degradation | from API ID32STA |
| 68375 | 16634 ChEBI | raffinose | - | fermentation | from API ID32STA |
| 68375 | 17992 ChEBI | sucrose | + | fermentation | from API ID32STA |
| 68375 | 27082 ChEBI | trehalose | + | fermentation | from API ID32STA |
| 68375 | 32528 ChEBI | turanose | + | fermentation | from API ID32STA |
| 68375 | 16199 ChEBI | urea | - | hydrolysis | from API ID32STA |
| @ref | ChEBI | Metabolite | Is antibiotic | Is resistant | Resistance conc. | |
|---|---|---|---|---|---|---|
| 68375 | 28368 | novobiocin | 1.8 µg | from API ID32STA |
| @ref | Chebi-ID | Metabolite | Production | |
|---|---|---|---|---|
| 68375 | 15688 ChEBI | acetoin | from API ID32STA |
| @ref | Chebi-ID | Metabolite | Voges-proskauer-test | |
|---|---|---|---|---|
| 68375 | 15688 ChEBI | acetoin | + | from API ID32STA |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68375 | alkaline phosphatase | + | 3.1.3.1 | from API ID32STA |
| 68375 | arginine dihydrolase | + | 3.5.3.6 | from API ID32STA |
| 68375 | beta-galactosidase | - | 3.2.1.23 | from API ID32STA |
| 68375 | beta-glucosidase | - | 3.2.1.21 | from API ID32STA |
| 68375 | beta-glucuronidase | - | 3.2.1.31 | from API ID32STA |
| 68375 | L-arginine arylamidase | - | from API ID32STA | |
| 68375 | ornithine decarboxylase | - | 4.1.1.17 | from API ID32STA |
| 68375 | pyrrolidonyl arylamidase | - | 3.4.19.3 | from API ID32STA |
| 68375 | urease | - | 3.5.1.5 | from API ID32STA |
| 18922 | Sample typelaboratory research strain originally derived from NCTC 8325-4 using UV and chemical mutagenesis |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 66792 | ASM2429682v1 assembly for Staphylococcus aureus subsp. aureus RN4220 | complete | 561307 | 98.89 | ||||
| 66792 | ASM1873216v1 assembly for Staphylococcus aureus subsp. aureus RN4220 | complete | 561307 | 98.79 | ||||
| 66792 | ASM1175161v1 assembly for Staphylococcus aureus subsp. aureus RN4220 | scaffold | 561307 | 73.59 | ||||
| 66792 | ASM21243v2 assembly for Staphylococcus aureus subsp. aureus RN4220 | contig | 561307 | 55.76 |
| @ref | Trait | Model | Prediction | Confidence in % | In training data |
|---|---|---|---|---|---|
| 125439 | spore_formation | BacteriaNetⓘ | no | 88.90 | no |
| 125439 | motility | BacteriaNetⓘ | no | 82.70 | no |
| 125439 | gram_stain | BacteriaNetⓘ | positive | 96.60 | no |
| 125439 | oxygen_tolerance | BacteriaNetⓘ | facultative anaerobe | 94.60 | no |
| @ref | Trait | Model | Prediction | Confidence in % | In training data |
|---|---|---|---|---|---|
| 125438 | gram-positive | gram-positiveⓘ | yes | 86.72 | no |
| 125438 | anaerobic | anaerobicⓘ | no | 99.44 | no |
| 125438 | aerobic | aerobicⓘ | yes | 51.79 | no |
| 125438 | spore-forming | spore-formingⓘ | no | 72.04 | no |
| 125438 | thermophilic | thermophileⓘ | no | 94.74 | no |
| 125438 | flagellated | motile2+ⓘ | no | 79.89 | no |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Genetics | CRISPR-Cas9 enables efficient genome engineering of the strictly lytic, broad-host-range staphylococcal bacteriophage K. | Fernbach J, Baggenstos J, Svorjova E-A, Riedo J, McCallin S, Loessner MJ, Kilcher S. | Appl Environ Microbiol | 10.1128/aem.02014-24 | 2025 | |
| Computational Pipeline for Targeted Integration and Variable Payload Expression in Bacteriophage Engineering. | Fernbach J, Hegedis E, Loessner MJ, Kilcher S. | ACS Synth Biol | 10.1021/acssynbio.5c00450 | 2025 | ||
| Pathogenicity | Invasion of intestinal cells by Staphylococcus warneri, a member of the human gut microbiota. | Louail R, Florin F, Bernard S, Michaud JB, Breton J, Achamrah N, Tavolacci MP, Coeffier M, Ribet D. | Gut Pathog | 10.1186/s13099-022-00528-7 | 2023 | |
| The effects of violet and blue light irradiation on ESKAPE pathogens and human cells in presence of cell culture media. | Bauer R, Hoenes K, Meurle T, Hessling M, Spellerberg B. | Sci Rep | 10.1038/s41598-021-04202-x | 2021 | ||
| Enzymology | The Resistome and Mobilome of Multidrug-Resistant Staphylococcus sciuri C2865 Unveil a Transferable Trimethoprim Resistance Gene, Designated dfrE, Spread Unnoticed. | Gomez-Sanz E, Haro-Moreno JM, Jensen SO, Roda-Garcia JJ, Lopez-Perez M. | mSystems | 10.1128/msystems.00511-21 | 2021 | |
| Pathogenicity | Staphylococcal Enterotoxins Dose-Dependently Modulate the Generation of Myeloid-Derived Suppressor Cells. | Stoll H, Ost M, Singh A, Mehling R, Neri D, Schafer I, Velic A, Macek B, Kretschmer D, Weidenmaier C, Hector A, Handgretinger R, Gotz F, Peschel A, Hartl D, Rieber N. | Front Cell Infect Microbiol | 10.3389/fcimb.2018.00321 | 2018 | |
| Metabolism | Efflux pump activity potentiates the evolution of antibiotic resistance across S. aureus isolates. | Papkou A, Hedge J, Kapel N, Young B, MacLean RC. | Nat Commun | 10.1038/s41467-020-17735-y | 2020 | |
| Metabolism | Novel Tet(L) Efflux Pump Variants Conferring Resistance to Tigecycline and Eravacycline in Staphylococcus Spp. | Wang N, Li D, Schwarz S, Qin S, Yao H, Du XD | Microbiol Spectr | 10.1128/Spectrum.01310-21 | 2021 | |
| Hypericin and Pheophorbide a Mediated Photodynamic Therapy Fighting MRSA Wound Infections: A Translational Study from In Vitro to In Vivo. | Chan BCL, Dharmaratne P, Wang B, Lau KM, Lee CC, Cheung DWS, Chan JYW, Yue GGL, Lau CBS, Wong CK, Fung KP, Ip M | Pharmaceutics | 10.3390/pharmaceutics13091399 | 2021 | ||
| Identification of the Multiresistance Gene poxtA in Oxazolidinone-Susceptible Staphylococcus haemolyticus and Staphylococcus saprophyticus of Pig and Feed Origins. | Chen L, Hu JX, Liu C, Liu J, Ma ZB, Tang ZY, Li YF, Zeng ZL | Pathogens | 10.3390/pathogens10050601 | 2021 | ||
| ROS induces NETosis by oxidizing DNA and initiating DNA repair. | Azzouz D, Khan MA, Palaniyar N | Cell Death Discov | 10.1038/s41420-021-00491-3 | 2021 | ||
| Enzymology | Multiplexed detection and differentiation of bacterial enzymes and bacteria by color-encoded sensor hydrogels. | Jia Z, Muller M, Le Gall T, Riool M, Muller M, Zaat SAJ, Montier T, Schonherr H | Bioact Mater | 10.1016/j.bioactmat.2021.04.022 | 2021 | |
| Metabolism | N-terminal acetylation of antimicrobial peptide L163 improves its stability against protease degradation. | Li D, Yang Y, Li R, Huang L, Wang Z, Deng Q, Dong S | J Pept Sci | 10.1002/psc.3337 | 2021 | |
| Pathogenicity | Inhibition of Staphylococcus aureus TetK and MsrA efflux pumps by hydroxyamines derived from lapachol and norlachol. | Figueredo FG, Parente RELT, Cavalcante-Figueredo MR, Figueiredo JG, da Silva RLP, Ferreira Matias EF, Silva TMS, Camara CA, de Morais Oliveira-Tintino CD, Tintino SR, Coutinho HDM, Fonteles MMF | J Bioenerg Biomembr | 10.1007/s10863-021-09885-5 | 2021 | |
| Pathogenicity | Effect of estragole over the RN4220 Staphylococcus aureus strain and its toxicity in Drosophila melanogaster. | Bezerra AH, Bezerra SR, Macedo NS, de Sousa Silveira Z, Dos Santos Barbosa CR, de Freitas TS, Muniz DF, de Sousa Junior DL, Junior JPS, Donato IA, Coutinho HDM, da Cunha FAB | Life Sci | 10.1016/j.lfs.2020.118675 | 2020 | |
| The Role of Amino Acid Substitution in HepT Toward Menaquinone Isoprenoid Chain Length Definition and Lysocin E Sensitivity in Staphylococcus aureus. | Panthee S, Paudel A, Hamamoto H, Uhlemann AC, Sekimizu K | Front Microbiol | 10.3389/fmicb.2020.02076 | 2020 | ||
| Genetics | Whole-genome sequence analyses of Glaesserella parasuis isolates reveals extensive genomic variation and diverse antibiotic resistance determinants. | Wan X, Li X, Osmundson T, Li C, Yan H | PeerJ | 10.7717/peerj.9293 | 2020 | |
| Pathogenicity | MsrA Efflux Pump Inhibitory Activity of Piper cubeba L.f. and its Phytoconstituents against Staphylococcus aureus RN4220. | Ahirrao P, Tambat R, Chandal N, Mahey N, Kamboj A, Jain UK, Singh IP, Jachak SM, Nandanwar HS | Chem Biodivers | 10.1002/cbdv.202000144 | 2020 | |
| Pathogenicity | Penicillin-binding protein PBP2a provides variable levels of protection toward different beta-lactams in Staphylococcus aureus RN4220. | Fergestad ME, Stamsas GA, Morales Angeles D, Salehian Z, Wasteson Y, Kjos M | Microbiologyopen | 10.1002/mbo3.1057 | 2020 | |
| A class A beta-lactamase produced by borderline oxacillin-resistant Staphylococcus aureus hydrolyses oxacillin. | Nomura R, Nakaminami H, Takasao K, Muramatsu S, Kato Y, Wajima T, Noguchi N | J Glob Antimicrob Resist | 10.1016/j.jgar.2020.03.002 | 2020 | ||
| Metabolism | In Staphylococcus aureus, the Particulate State of the Cell Envelope Is Required for the Efficient Induction of Host Defense Responses. | Kim B, Jiang T, Bae JH, Yun HS, Jang SH, Kim JH, Kim JD, Hur JH, Shibata K, Kurokawa K, Jung Y, Peschel A, Bae T, Lee BL | Infect Immun | 10.1128/IAI.00674-19 | 2019 | |
| Pathogenicity | Silviavirus phage MR003 displays a broad host range against methicillin-resistant Staphylococcus aureus of human origin. | Peng C, Hanawa T, Azam AH, LeBlanc C, Ung P, Matsuda T, Onishi H, Miyanaga K, Tanji Y | Appl Microbiol Biotechnol | 10.1007/s00253-019-10039-2 | 2019 | |
| Pathogenicity | The tva(A) Gene from Brachyspira hyodysenteriae Confers Decreased Susceptibility to Pleuromutilins and Streptogramin A in Escherichia coli. | Garcia-Martin AB, Schwendener S, Perreten V | Antimicrob Agents Chemother | 10.1128/AAC.00930-19 | 2019 | |
| Pathogenicity | Molecular characterization of multi-drug resistant coagulase negative cocci in non-hospital environment. | Nwibo DD, Panthee S, Hamamoto H, Sekimizu K | Drug Discov Ther | 10.5582/ddt.2019.01031 | 2019 | |
| Pathogenicity | Capsaicin and gingerol analogues inhibit the growth of efflux-multidrug resistant bacteria and R-plasmids conjugal transfer. | Oyedemi BO, Kotsia EM, Stapleton PD, Gibbons S | J Ethnopharmacol | 10.1016/j.jep.2019.111871 | 2019 | |
| Metabolism | Use of the counter selectable marker PheS* for genome engineering in Staphylococcus aureus. | Schuster CF, Howard SA, Grundling A | Microbiology (Reading) | 10.1099/mic.0.000791 | 2019 | |
| Pathogenicity | Characterization of the Multi-Drug Resistance Gene cfr in Methicillin-Resistant Staphylococcus aureus (MRSA) Strains Isolated From Animals and Humans in China. | Li SM, Zhou YF, Li L, Fang LX, Duan JH, Liu FR, Liang HQ, Wu YT, Gu WQ, Liao XP, Sun J, Xiong YQ, Liu YH | Front Microbiol | 10.3389/fmicb.2018.02925 | 2018 | |
| Metabolism | Intracellular Accumulation of Linezolid and Florfenicol in OptrA-Producing Enterococcus faecalis and Staphylococcus aureus. | Wang Y, Li X, Wang Y, Schwarz S, Shen J, Xia X | Molecules | 10.3390/molecules23123195 | 2018 | |
| Enzymology | Isovalerylshikonin, a new resistance-modifying agent from Arnebia euchroma, supresses antimicrobial resistance of drug-resistant Staphylococcus aureus. | He JM, Sun SC, Sun ZL, Chen JT, Mu Q | Int J Antimicrob Agents | 10.1016/j.ijantimicag.2018.08.021 | 2018 | |
| Metabolism | Changes in resistance to and antimicrobial activity of antibiotics during in vitro human digestion. | Lee SY, Kim OY, Yoon SY, Lee DY, Hur SJ | J Glob Antimicrob Resist | 10.1016/j.jgar.2018.08.017 | 2018 | |
| Enzymology | Creation of deletion and insertion clonal complex 8 Staphylococcus aureus mutants using a common cloning vector. | Chen P, Karna SLR, Leung KP | J Microbiol Methods | 10.1016/j.mimet.2018.05.008 | 2018 | |
| Pathogenicity | Biophysical evaluation of cardiolipin content as a regulator of the membrane lytic effect of antimicrobial peptides. | Hernandez-Villa L, Manrique-Moreno M, Leidy C, Jemiola-Rzeminska M, Ortiz C, Strzalka K | Biophys Chem | 10.1016/j.bpc.2018.04.001 | 2018 | |
| Construction of Stable Fluorescent Reporter Plasmids for Use in Staphylococcus aureus. | Rodriguez MD, Paul Z, Wood CE, Rice KC, Triplett EW | Front Microbiol | 10.3389/fmicb.2017.02491 | 2017 | ||
| Pathogenicity | Safe Staphylococcal Platform for the Development of Multivalent Nanoscale Vesicles against Viral Infections. | Yuan J, Yang J, Hu Z, Yang Y, Shang W, Hu Q, Zheng Y, Peng H, Zhang X, Cai X, Zhu J, Li M, Hu X, Zhou R, Rao X | Nano Lett | 10.1021/acs.nanolett.7b03893 | 2018 | |
| Phenotype | Tannic acid affects the phenotype of Staphylococcus aureus resistant to tetracycline and erythromycin by inhibition of efflux pumps. | Tintino SR, Morais-Tintino CD, Campina FF, Costa MDS, Menezes IRA, de Matos YMLS, Calixto-Junior JT, Pereira PS, Siqueira-Junior JP, Leal-Balbino TC, Coutinho HDM, Balbino VQ | Bioorg Chem | 10.1016/j.bioorg.2017.08.004 | 2017 | |
| Metabolism | The development of fluorescent protein tracing vectors for multicolor imaging of clinically isolated Staphylococcus aureus. | Kato F, Nakamura M, Sugai M | Sci Rep | 10.1038/s41598-017-02930-7 | 2017 | |
| Pathogenicity | Inhibitory effects of flavonoids on biofilm formation by Staphylococcus aureus that overexpresses efflux protein genes. | Lopes LAA, Dos Santos Rodrigues JB, Magnani M, de Souza EL, de Siqueira-Junior JP | Microb Pathog | 10.1016/j.micpath.2017.03.033 | 2017 | |
| Pathogenicity | Cholesterol and ergosterol affect the activity of Staphylococcus aureus antibiotic efflux pumps. | Tintino SR, Oliveira-Tintino CD, Campina FF, Costa MS, Cruz RP, Pereira RL, Andrade JC, Sousa EO, Siqueira-Junior JP, Coutinho HD, Leal-Balbino TC, Balbino VQ | Microb Pathog | 10.1016/j.micpath.2017.01.019 | 2017 | |
| Efficient transformation of Staphylococcus aureus using multi-pulse electroporation. | Hisatsune J, Sato'o Y, Yu L, Kutsuno S, Hayakawa Y, Sugai M | J Microbiol Methods | 10.1016/j.mimet.2016.08.012 | 2016 | ||
| Action of cholecalciferol and alpha-tocopherol on Staphylococcus aureus efflux pumps. | Tintino SR, Morais-Tintino CD, Campina FF, Pereira RL, Costa Mdo S, Braga MF, Limaverde PW, Andrade JC, Siqueira-Junior JP, Coutinho HD, Balbino VQ, Leal-Balbino TC, Ribeiro-Filho J, Quintans-Junior LJ | EXCLI J | 10.17179/excli2016-277 | 2016 | ||
| Metabolism | Dissecting the regulation of bile-induced biofilm formation in Staphylococcus aureus. | Ulluwishewa D, Wang L, Pereira C, Flynn S, Cain E, Stick S, Reen FJ, Ramsay JP, O'Gara F | Microbiology (Reading) | 10.1099/mic.0.000317 | 2016 | |
| Synthesis, characterization and biological evaluation of a new photoactive hydrogel against Gram-positive and Gram-negative bacteria. | Spagnul C, Greenman J, Wainwright M, Kamil Z, Boyle RW | J Mater Chem B | 10.1039/c5tb02569a | 2016 | ||
| Pathogenicity | In vitro activity of human and animal cathelicidins against livestock-associated methicillin-resistant Staphylococcus aureus. | Blodkamp S, Kadlec K, Gutsmann T, Naim HY, von Kockritz-Blickwede M, Schwarz S | Vet Microbiol | 10.1016/j.vetmic.2015.09.018 | 2015 | |
| Pathogenicity | Compounds in a particular production lot of tryptic soy broth inhibit Staphylococcus aureus cell growth. | Ishii M, Matsumoto Y, Sekimizu K | Drug Discov Ther | 10.5582/ddt.2015.01030 | 2015 | |
| The Essential WalK Histidine Kinase and WalR Regulator Differentially Mediate Autolysis of Staphylococcus aureus RN4220. | Zheng L, Yan M, Fan F, Ji Y | J Nat Sci | 2015 | |||
| Enzymology | Complete Bypass of Restriction Systems for Major Staphylococcus aureus Lineages. | Monk IR, Tree JJ, Howden BP, Stinear TP, Foster TJ | mBio | 10.1128/mBio.00308-15 | 2015 | |
| Pathogenicity | Detection of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates using a combination of delta-hemolysis assay and Etest. | Chang SC, Liu TP, Chen CJ, Lin LC, Lu JJ | Diagn Microbiol Infect Dis | 10.1016/j.diagmicrobio.2014.12.006 | 2014 | |
| Enzymology | Enhancing DNA electro-transformation efficiency on a clinical Staphylococcus capitis isolate. | Cui B, Smooker PM, Rouch DA, Deighton MA | J Microbiol Methods | 10.1016/j.mimet.2014.11.012 | 2014 | |
| Pathogenicity | Combating against methicillin-resistant Staphylococcus aureus - two fatty acids from Purslane (Portulaca oleracea L.) exhibit synergistic effects with erythromycin. | Chan BC, Han XQ, Lui SL, Wong CW, Wang TB, Cheung DW, Cheng SW, Ip M, Han SQ, Yang XS, Jolivalt C, Lau CB, Leung PC, Fung KP | J Pharm Pharmacol | 10.1111/jphp.12315 | 2014 | |
| Phylogeny | The Staphylococcal Cassette Chromosome mec type V from Staphylococcus aureus ST398 is packaged into bacteriophage capsids. | Chlebowicz MA, Maslanova I, Kuntova L, Grundmann H, Pantucek R, Doskar J, van Dijl JM, Buist G | Int J Med Microbiol | 10.1016/j.ijmm.2014.05.010 | 2014 | |
| Pathogenicity | Synthesis and antibacterial evaluation of amino acid-antibiotic conjugates. | Ibrahim MA, Panda SS, Birs AS, Serrano JC, Gonzalez CF, Alamry KA, Katritzky AR | Bioorg Med Chem Lett | 10.1016/j.bmcl.2014.01.065 | 2014 | |
| Enzymology | Identification of the novel lincosamide resistance gene lnu(E) truncated by ISEnfa5-cfr-ISEnfa5 insertion in Streptococcus suis: de novo synthesis and confirmation of functional activity in Staphylococcus aureus. | Zhao Q, Wendlandt S, Li H, Li J, Wu C, Shen J, Schwarz S, Wang Y | Antimicrob Agents Chemother | 10.1128/AAC.02007-13 | 2013 | |
| Pathogenicity | Flavonoids from Sophora moorcroftiana and their synergistic antibacterial effects on MRSA. | Wang SY, Sun ZL, Liu T, Gibbons S, Zhang WJ, Qing M | Phytother Res | 10.1002/ptr.5098 | 2013 | |
| Genetics | Identification of a novel vga(E) gene variant that confers resistance to pleuromutilins, lincosamides and streptogramin A antibiotics in staphylococci of porcine origin. | Li J, Li B, Wendlandt S, Schwarz S, Wang Y, Wu C, Ma Z, Shen J | J Antimicrob Chemother | 10.1093/jac/dkt482 | 2013 | |
| Genetics | Genetic variation in the Staphylococcus aureus 8325 strain lineage revealed by whole-genome sequencing. | Baek KT, Frees D, Renzoni A, Barras C, Rodriguez N, Manzano C, Kelley WL | PLoS One | 10.1371/journal.pone.0077122 | 2013 | |
| Enzymology | Prevalence of fusB in Staphylococcus aureus clinical isolates. | Huang J, Ye M, Ding H, Guo Q, Ding B, Wang M | J Med Microbiol | 10.1099/jmm.0.058305-0 | 2013 | |
| Pathogenicity | Novel erm(T)-carrying multiresistance plasmids from porcine and human isolates of methicillin-resistant Staphylococcus aureus ST398 that also harbor cadmium and copper resistance determinants. | Gomez-Sanz E, Kadlec K, Fessler AT, Zarazaga M, Torres C, Schwarz S | Antimicrob Agents Chemother | 10.1128/AAC.00171-13 | 2013 | |
| Enzymology | Stably luminescent Staphylococcus aureus clinical strains for use in bioluminescent imaging. | Plaut RD, Mocca CP, Prabhakara R, Merkel TJ, Stibitz S | PLoS One | 10.1371/journal.pone.0059232 | 2013 | |
| Metabolism | Synergistic effects of diosmetin with erythromycin against ABC transporter over-expressed methicillin-resistant Staphylococcus aureus (MRSA) RN4220/pUL5054 and inhibition of MRSA pyruvate kinase. | Chan BC, Ip M, Gong H, Lui SL, See RH, Jolivalt C, Fung KP, Leung PC, Reiner NE, Lau CB | Phytomedicine | 10.1016/j.phymed.2013.02.007 | 2013 | |
| Enzymology | Detection and new genetic environment of the pleuromutilin-lincosamide-streptogramin A resistance gene lsa(E) in methicillin-resistant Staphylococcus aureus of swine origin. | Li B, Wendlandt S, Yao J, Liu Y, Zhang Q, Shi Z, Wei J, Shao D, Schwarz S, Wang S, Ma Z | J Antimicrob Chemother | 10.1093/jac/dkt015 | 2013 | |
| Pathogenicity | Synthesis and antimicrobial evaluation of L-phenylalanine-derived C5-substituted rhodanine and chalcone derivatives containing thiobarbituric acid or 2-thioxo-4-thiazolidinone. | Jin X, Zheng CJ, Song MX, Wu Y, Sun LP, Li YJ, Yu LJ, Piao HR | Eur J Med Chem | 10.1016/j.ejmech.2012.08.026 | 2012 | |
| Metabolism | The extracytoplasmic function sigma factor sigmaS protects against both intracellular and extracytoplasmic stresses in Staphylococcus aureus. | Miller HK, Carroll RK, Burda WN, Krute CN, Davenport JE, Shaw LN | J Bacteriol | 10.1128/JB.00484-12 | 2012 | |
| Metabolism | Comparative expression analysis of two thermostable nuclease genes in Staphylococcus aureus. | Hu Y, Xie Y, Tang J, Shi X | Foodborne Pathog Dis | 10.1089/fpd.2011.1033 | 2012 | |
| Pathogenicity | Direct and synergistic hemolysis caused by Staphylococcus phenol-soluble modulins: implications for diagnosis and pathogenesis. | Cheung GY, Duong AC, Otto M | Microbes Infect | 10.1016/j.micinf.2011.11.013 | 2011 | |
| Metabolism | Genes involved in immunity to and secretion of aureocin A53, an atypical class II bacteriocin produced by Staphylococcus aureus A53. | Nascimento Jdos S, Coelho ML, Ceotto H, Potter A, Fleming LR, Salehian Z, Nes IF, Bastos Mdo C | J Bacteriol | 10.1128/JB.06203-11 | 2011 | |
| Metabolism | Formylated peptides are important virulence factors in Staphylococcus aureus arthritis in mice. | Gjertsson I, Jonsson IM, Peschel A, Tarkowski A, Lindholm C | J Infect Dis | 10.1093/infdis/jir713 | 2011 | |
| Metabolism | Lysis-deficient phages as novel therapeutic agents for controlling bacterial infection. | Paul VD, Sundarrajan S, Rajagopalan SS, Hariharan S, Kempashanaiah N, Padmanabhan S, Sriram B, Ramachandran J | BMC Microbiol | 10.1186/1471-2180-11-195 | 2011 | |
| Metabolism | The minor groove-binding agent ELB-21 forms multiple interstrand and intrastrand covalent cross-links with duplex DNA and displays potent bactericidal activity against methicillin-resistant Staphylococcus aureus. | Rosado H, Rahman KM, Feuerbaum EA, Hinds J, Thurston DE, Taylor PW | J Antimicrob Chemother | 10.1093/jac/dkr044 | 2011 | |
| Metabolism | Duckweed (Lemna minor) as a model plant system for the study of human microbial pathogenesis. | Zhang Y, Hu Y, Yang B, Ma F, Lu P, Li L, Wan C, Rayner S, Chen S | PLoS One | 10.1371/journal.pone.0013527 | 2010 | |
| Metabolism | Characterization of a Staphylococcus aureus surface virulence factor that promotes resistance to oxidative killing and infectious endocarditis. | Malachowa N, Kohler PL, Schlievert PM, Chuang ON, Dunny GM, Kobayashi SD, Miedzobrodzki J, Bohach GA, Seo KS | Infect Immun | 10.1128/IAI.00736-10 | 2010 | |
| Pathogenicity | Cloning and occurrence of czrC, a gene conferring cadmium and zinc resistance in methicillin-resistant Staphylococcus aureus CC398 isolates. | Cavaco LM, Hasman H, Stegger M, Andersen PS, Skov R, Fluit AC, Ito T, Aarestrup FM | Antimicrob Agents Chemother | 10.1128/AAC.00058-10 | 2010 | |
| Enzymology | Wound healing properties and kill kinetics of Clerodendron splendens G. Don, a Ghanaian wound healing plant. | Gbedema SY, Emelia K, Francis A, Kofi A, Eric W | Pharmacognosy Res | 10.4103/0974-8490.62948 | 2010 | |
| Metabolism | Glycosylation of wall teichoic acid in Staphylococcus aureus by TarM. | Xia G, Maier L, Sanchez-Carballo P, Li M, Otto M, Holst O, Peschel A | J Biol Chem | 10.1074/jbc.M109.096172 | 2010 | |
| Pathogenicity | Activity of linezolid in an in vitro pharmacokinetic-pharmacodynamic model using different dosages and Staphylococcus aureus and Enterococcus faecalis strains with and without a hypermutator phenotype. | Ba BB, Arpin C, Bikie Bi Nso B, Dubois V, Saux MC, Quentin C | Antimicrob Agents Chemother | 10.1128/AAC.01022-09 | 2010 | |
| Pathogenicity | Inhibition of Staphylococcus epidermidis biofilm formation by rabbit polyclonal antibodies against the SesC protein. | Shahrooei M, Hira V, Stijlemans B, Merckx R, Hermans PW, Van Eldere J | Infect Immun | 10.1128/IAI.01464-08 | 2009 | |
| Enzymology | Inactivation of the SauI type I restriction-modification system is not sufficient to generate Staphylococcus aureus strains capable of efficiently accepting foreign DNA. | Veiga H, Pinho MG | Appl Environ Microbiol | 10.1128/AEM.01862-08 | 2009 | |
| Metabolism | Antibiotics, arsenate and H2O2 induce the promoter of Staphylococcus aureus cspC gene more strongly than cold. | Chanda PK, Mondal R, Sau K, Sau S | J Basic Microbiol | 10.1002/jobm.200800065 | 2009 | |
| Pathogenicity | Antibacterial, antioxidant and fibroblast growth stimulation of aqueous extracts of Ficus asperifolia Miq. and Gossypium arboreum L., wound-healing plants of Ghana. | Annan K, Houghton PJ | J Ethnopharmacol | 10.1016/j.jep.2008.06.017 | 2008 | |
| Pathogenicity | Frequencies of resistance to Melaleuca alternifolia (tea tree) oil and rifampicin in Staphylococcus aureus, Staphylococcus epidermidis and Enterococcus faecalis. | Hammer KA, Carson CF, Riley TV | Int J Antimicrob Agents | 10.1016/j.ijantimicag.2008.03.013 | 2008 | |
| Enzymology | Two thermostable nucleases coexisted in Staphylococcus aureus: evidence from mutagenesis and in vitro expression. | Tang J, Zhou R, Shi X, Kang M, Wang H, Chen H | FEMS Microbiol Lett | 10.1111/j.1574-6968.2008.01194.x | 2008 | |
| Transcriptome | Differences in potential for selection of clindamycin-resistant mutants between inducible erm(A) and erm(C) Staphylococcus aureus genes. | Daurel C, Huet C, Dhalluin A, Bes M, Etienne J, Leclercq R | J Clin Microbiol | 10.1128/JCM.01925-07 | 2007 | |
| Pathogenicity | Detection of antistaphylococcal and toxic compounds by biological assay systems developed with a reporter Staphylococcus aureus strain harboring a heat inducible promoter - lacZ transcriptional fusion. | Chanda PK, Ganguly T, Das M, Lee CY, Luong TT, Sau S | J Biochem Mol Biol | 10.5483/bmbrep.2007.40.6.936 | 2007 | |
| Pathogenicity | Role of hypermutability on bacterial fitness and emergence of resistance in experimental osteomyelitis due to Staphylococcus aureus. | Daurel C, Prunier AL, Chau F, Garry L, Leclercq R, Fantin B | FEMS Immunol Med Microbiol | 10.1111/j.1574-695X.2007.00310.x | 2007 | |
| Pathogenicity | Transduction of the plasmid encoding antiseptic resistance gene qacB in Staphylococcus aureus. | Nakaminami H, Noguchi N, Nishijima S, Kurokawa I, So H, Sasatsu M | Biol Pharm Bull | 10.1248/bpb.30.1412 | 2007 | |
| Metabolism | Role of a qnr-like gene in the intrinsic resistance of Enterococcus faecalis to fluoroquinolones. | Arsene S, Leclercq R | Antimicrob Agents Chemother | 10.1128/AAC.00274-07 | 2007 | |
| Pathogenicity | Specific Bifidobacterium strains isolated from elderly subjects inhibit growth of Staphylococcus aureus. | Lahtinen SJ, Jalonen L, Ouwehand AC, Salminen SJ | Int J Food Microbiol | 10.1016/j.ijfoodmicro.2007.02.023 | 2007 | |
| Enzymology | Identification and characterization of nine novel types of small staphylococcal plasmids carrying the lincosamide nucleotidyltransferase gene lnu(A). | Luthje P, von Kockritz-Blickwede M, Schwarz S | J Antimicrob Chemother | 10.1093/jac/dkm008 | 2007 | |
| Metabolism | Repression of Staphylococcus aureus SrrAB using inducible antisense srrA alters growth and virulence factor transcript levels. | Pragman AA, Ji Y, Schlievert PM | Biochemistry | 10.1021/bi0603266 | 2007 | |
| Enzymology | Sau1: a novel lineage-specific type I restriction-modification system that blocks horizontal gene transfer into Staphylococcus aureus and between S. aureus isolates of different lineages. | Waldron DE, Lindsay JA | J Bacteriol | 10.1128/JB.00418-06 | 2006 | |
| Enzymology | A novel antimicrobial epoxide isolated from larval Galleria mellonella infected by the nematode symbiont, Photorhabdus luminescens (Enterobacteriaceae). | Hu K, Li J, Li B, Webster JM, Chen G | Bioorg Med Chem | 10.1016/j.bmc.2006.01.025 | 2006 | |
| Pathogenicity | A slipped-mispairing mutation in AgrA of laboratory strains and clinical isolates results in delayed activation of agr and failure to translate delta- and alpha-haemolysins. | Traber K, Novick R | Mol Microbiol | 10.1111/j.1365-2958.2006.04986.x | 2006 | |
| Genetics | Staphylococcal tetracycline-MLSB resistance plasmid pSTE2 is the product of an RSA-mediated in vivo recombination. | Hauschild T, Luthje P, Schwarz S | J Antimicrob Chemother | 10.1093/jac/dki207 | 2005 | |
| Enzymology | Role of mutS and mutL genes in hypermutability and recombination in Staphylococcus aureus. | Prunier AL, Leclercq R | J Bacteriol | 10.1128/JB.187.10.3455-3464.2005 | 2005 | |
| Enzymology | Sau42I, a BcgI-like restriction-modification system encoded by the Staphylococcus aureus quadruple-converting phage Phi42. | Dempsey RM, Carroll D, Kong H, Higgins L, Keane CT, Coleman DC | Microbiology (Reading) | 10.1099/mic.0.27646-0 | 2005 | |
| Pathogenicity | Intravitreal human immune globulin in a rabbit model of Staphylococcus aureus toxin-mediated endophthalmitis: a potential adjunct in the treatment of endophthalmitis. | Han DP | Trans Am Ophthalmol Soc | 2004 | ||
| Pathogenicity | Enhanced resistance to erythromycin is conferred by the enterococcal msrC determinant in Staphylococcus aureus. | Reynolds E, Cove JH | J Antimicrob Chemother | 10.1093/jac/dkh541 | 2005 | |
| Pathogenicity | Characterization of a bifunctional aminoglycoside-modifying enzyme with novel substrate specificity and its gene from a clinical isolate of methicillin-resistant Staphylococcus aureus with high arbekacin resistance. | Ishino K, Ishikawa J, Ikeda Y, Hotta K | J Antibiot (Tokyo) | 10.7164/antibiotics.57.679 | 2004 | |
| Pathogenicity | Comparison of assays for detection of agents causing membrane damage in Staphylococcus aureus. | O'Neill AJ, Miller K, Oliva B, Chopra I | J Antimicrob Chemother | 10.1093/jac/dkh476 | 2004 | |
| Phenotype | Bactericidal activity of quinupristin-dalfopristin against strains of Staphylococcus aureus with the MLS(B) phenotype of resistance according to the erm gene type. | Clarebout G, Nativelle E, Bozdogan B, Villers C, Leclercq R | Int J Antimicrob Agents | 10.1016/j.ijantimicag.2004.06.016 | 2004 | |
| Metabolism | Intravitreally injected human immunoglobulin attenuates the effects of Staphylococcus aureus culture supernatant in a rabbit model of toxin-mediated endophthalmitis. | Perkins SL, Han DP, Burke JM, Schlievert PM, Wirostko WJ, Tarasewicz DG, Skumatz CM | Arch Ophthalmol | 10.1001/archopht.122.10.1499 | 2004 | |
| Pathogenicity | Nucleotide sequence and organization of the multiresistance plasmid pSCFS1 from Staphylococcus sciuri. | Kehrenberg C, Ojo KK, Schwarz S | J Antimicrob Chemother | 10.1093/jac/dkh457 | 2004 | |
| Pathogenicity | The cme gene of Clostridium difficile confers multidrug resistance in Enterococcus faecalis. | Lebel S, Bouttier S, Lambert T | FEMS Microbiol Lett | 10.1016/j.femsle.2004.07.022 | 2004 | |
| Pathogenicity | Discarding multidrug resistance inducers, the possible role of a biosensing reporter in antimicrobial discovery. | Galluzzi L, Virtanen P, Karp M | Luminescence | 10.1002/bio.771 | 2004 | |
| Metabolism | Low-proline environments impair growth, proline transport and in vivo survival of Staphylococcus aureus strain-specific putP mutants. | Schwan WR, Wetzel KJ, Gomez TS, Stiles MA, Beitlich BD, Grunwald S | Microbiology (Reading) | 10.1099/mic.0.26710-0 | 2004 | |
| Effect of disruption of Staphylococcus aureus PBP4 gene on resistance to beta-lactam antibiotics. | Katayama Y, Zhang HZ, Chambers HF | Microb Drug Resist | 10.1089/107662903322762752 | 2003 | ||
| Pathogenicity | Inactivation of mprF affects vancomycin susceptibility in Staphylococcus aureus. | Ruzin A, Severin A, Moghazeh SL, Etienne J, Bradford PA, Projan SJ, Shlaes DM | Biochim Biophys Acta | 10.1016/s0304-4165(03)00028-x | 2003 | |
| Pathogenicity | Biflavonoids with cytotoxic and antibacterial activity from Ochna macrocalyx. | Tang S, Bremner P, Kortenkamp A, Schlage C, Gray AI, Gibbons S, Heinrich M | Planta Med | 10.1055/s-2003-38478 | 2003 | |
| Pathogenicity | Molecular analysis of fusidic acid resistance in Staphylococcus aureus. | Besier S, Ludwig A, Brade V, Wichelhaus TA | Mol Microbiol | 10.1046/j.1365-2958.2003.03307.x | 2003 | |
| Pathogenicity | Characterization of a holin (HolNU3-1) in methicillin-resistant Staphylococcus aureus host. | Horii T, Suzuki Y, Kobayashi M | FEMS Immunol Med Microbiol | 10.1111/j.1574-695X.2002.tb00638.x | 2002 | |
| Pathogenicity | An elevated mutation frequency favors development of vancomycin resistance in Staphylococcus aureus. | Schaaff F, Reipert A, Bierbaum G | Antimicrob Agents Chemother | 10.1128/AAC.46.11.3540-3548.2002 | 2002 | |
| Pathogenicity | Insertional inactivation of mutS in Staphylococcus aureus reveals potential for elevated mutation frequencies, although the prevalence of mutators in clinical isolates is low. | O'Neill AJ, Chopra I | J Antimicrob Chemother | 10.1093/jac/dkf118 | 2002 | |
| Metabolism | Small-colony mutants of Staphylococcus aureus allow selection of gyrase-mediated resistance to dual-target fluoroquinolones. | Pan XS, Hamlyn PJ, Talens-Visconti R, Alovero FL, Manzo RH, Fisher LM | Antimicrob Agents Chemother | 10.1128/AAC.46.8.2498-2506.2002 | 2002 | |
| Pathogenicity | Resistance to quinupristin-dalfopristin due to mutation of L22 ribosomal protein in Staphylococcus aureus. | Malbruny B, Canu A, Bozdogan B, Fantin B, Zarrouk V, Dutka-Malen S, Feger C, Leclercq R | Antimicrob Agents Chemother | 10.1128/AAC.46.7.2200-2207.2002 | 2002 | |
| Cultivation | Genetic linkage between resistance to quaternary ammonium compounds and beta-lactam antibiotics in food-related Staphylococcus spp. | Sidhu MS, Heir E, Sorum H, Holck A | Microb Drug Resist | 10.1089/10766290152773374 | 2001 | |
| Metabolism | Direct quantitation of the numbers of individual penicillin-binding proteins per cell in Staphylococcus aureus. | Pucci MJ, Dougherty TJ | J Bacteriol | 10.1128/JB.184.2.588-591.2002 | 2002 | |
| Cultivation | Measurement of effects of antibiotics in bioluminescent Staphylococcus aureus RN4220. | Tenhami M, Hakkila K, Karp M | Antimicrob Agents Chemother | 10.1128/AAC.45.12.3456-3461.2001 | 2001 | |
| Metabolism | Complementation of the essential peptidoglycan transpeptidase function of penicillin-binding protein 2 (PBP2) by the drug resistance protein PBP2A in Staphylococcus aureus. | Pinho MG, Filipe SR, de Lencastre H, Tomasz A | J Bacteriol | 10.1128/JB.183.22.6525-6531.2001 | 2001 | |
| Metabolism | The Fbe (SdrG) protein of Staphylococcus epidermidis HB promotes bacterial adherence to fibrinogen. | Hartford O, O'Brien L, Schofield K, Wells J, Foster TJ | Microbiology (Reading) | 10.1099/00221287-147-9-2545 | 2001 | |
| Pathogenicity | Phage conversion of Panton-Valentine leukocidin in Staphylococcus aureus: molecular analysis of a PVL-converting phage, phiSLT. | Narita S, Kaneko J, Chiba J, Piemont Y, Jarraud S, Etienne J, Kamio Y | Gene | 10.1016/s0378-1119(01)00390-0 | 2001 | |
| Metabolism | Biosynthesis of the glycolipid anchor in lipoteichoic acid of Staphylococcus aureus RN4220: role of YpfP, the diglucosyldiacylglycerol synthase. | Kiriukhin MY, Debabov DV, Shinabarger DL, Neuhaus FC | J Bacteriol | 10.1128/JB.183.11.3506-3514.2001 | 2001 | |
| Genetics | A method for demonstrating gene essentiality in Staphylococcus aureus. | Jana M, Luong TT, Komatsuzawa H, Shigeta M, Lee CY | Plasmid | 10.1006/plas.2000.1473 | 2000 | |
| Pathogenicity | Effects of genes encoding resistance to streptogramins A and B on the activity of quinupristin-dalfopristin against Enterococcus faecium. | Bozdogan B, Leclercq R | Antimicrob Agents Chemother | 10.1128/AAC.43.11.2720 | 1999 | |
| Enzymology | Transposition of IS1181 in the genomes of Staphylococcus and Listeria. | Chesneau O, Lailler R, Derbise A, El Solh N | FEMS Microbiol Lett | 10.1111/j.1574-6968.1999.tb13718.x | 1999 | |
| Enzymology | Activities of trovafloxacin compared with those of other fluoroquinolones against purified topoisomerases and gyrA and grlA mutants of Staphylococcus aureus. | Gootz TD, Zaniewski RP, Haskell SL, Kaczmarek FS, Maurice AE | Antimicrob Agents Chemother | 10.1128/AAC.43.8.1845 | 1999 | |
| Genetics | Genetic analysis of the cap5 locus of Staphylococcus aureus. | Wann ER, Dassy B, Fournier JM, Foster TJ | FEMS Microbiol Lett | 10.1111/j.1574-6968.1999.tb13360.x | 1999 | |
| Pathogenicity | Luminescent bacterial sensor for cadmium and lead. | Tauriainen S, Karp M, Chang W, Virta M | Biosens Bioelectron | 10.1016/s0956-5663(98)00027-x | 1998 | |
| Enzymology | Effects of mutations in GrlA of topoisomerase IV from Staphylococcus aureus on quinolone and coumarin activity. | Fournier B, Hooper DC | Antimicrob Agents Chemother | 10.1128/AAC.42.8.2109 | 1998 | |
| Pathogenicity | A new ketolide, HMR 3004, active against streptococci inducibly resistant to erythromycin. | Rosato A, Vicarini H, Bonnefoy A, Chantot JF, Leclercq R | Antimicrob Agents Chemother | 10.1128/AAC.42.6.1392 | 1998 | |
| Enzymology | Penicillin-binding protein 1 of Staphylococcus aureus is essential for growth. | Wada A, Watanabe H | J Bacteriol | 10.1128/JB.180.10.2759-2765.1998 | 1998 | |
| Enzymology | Recombinant luminescent bacteria for measuring bioavailable arsenite and antimonite. | Tauriainen S, Karp M, Chang W, Virta M | Appl Environ Microbiol | 10.1128/aem.63.11.4456-4461.1997 | 1997 | |
| Pathogenicity | Quinolone susceptibility of norA-disrupted Staphylococcus aureus. | Yamada H, Kurose-Hamada S, Fukuda Y, Mitsuyama J, Takahata M, Minami S, Watanabe Y, Narita H | Antimicrob Agents Chemother | 10.1128/AAC.41.10.2308 | 1997 | |
| Osmoadaptation by Staphylococcus aureus : Analysis of Several Strains Linked to Food Poisoning Outbreaks. | Louch HA, Eck ML, Miller KJ | J Food Prot | 10.4315/0362-028X-60.2.139 | 1997 | ||
| Enzymology | Purification of Staphylococcus aureus beta-toxin: comparison of three isoelectric focusing methods. | Gaskin DK, Bohach GA, Schlievert PM, Hovde CJ | Protein Expr Purif | 10.1006/prep.1996.0664 | 1997 | |
| Phenotype | Minimal functional system required for expression of erythromycin resistance by msrA in Staphylococcus aureus RN4220. | Ross JI, Eady EA, Cove JH, Baumberg S | Gene | 10.1016/s0378-1119(96)00541-0 | 1996 | |
| Enzymology | Purification and partial characterization of a novel antibacterial agent (Bac1829) Produced by Staphylococcus aureus KSI1829. | Crupper SS, Iandolo JJ | Appl Environ Microbiol | 10.1128/aem.62.9.3171-3175.1996 | 1996 | |
| Genetics | Alterations in the DNA topoisomerase IV grlA gene responsible for quinolone resistance in Staphylococcus aureus. | Yamagishi J, Kojima T, Oyamada Y, Fujimoto K, Hattori H, Nakamura S, Inoue M | Antimicrob Agents Chemother | 10.1128/AAC.40.5.1157 | 1996 | |
| Phenotype | Suppression of the thermosensitive replication phenotype of the derivative plasmid of pI9789::Tn552 in Staphylococcus aureus may involve integration of the plasmid into the host chromosome. | Sohail M, Dyke KG | FEMS Microbiol Lett | 10.1111/j.1574-6968.1996.tb08038.x | 1996 | |
| Enzymology | Analysis of gyrA and grlA mutations in stepwise-selected ciprofloxacin-resistant mutants of Staphylococcus aureus. | Ferrero L, Cameron B, Crouzet J | Antimicrob Agents Chemother | 10.1128/AAC.39.7.1554 | 1995 | |
| Metabolism | The lysostaphin endopeptidase resistance gene (epr) specifies modification of peptidoglycan cross bridges in Staphylococcus simulans and Staphylococcus aureus. | DeHart HP, Heath HE, Heath LS, LeBlanc PA, Sloan GL | Appl Environ Microbiol | 10.1128/aem.61.4.1475-1479.1995 | 1995 | |
| Enzymology | A genetic and molecular characterization of the recA gene from Staphylococcus aureus. | Bayles KW, Brunskill EW, Iandolo JJ, Hruska LL, Huang S, Pattee PA, Smiley BK, Yasbin RE | Gene | 10.1016/0378-1119(94)90033-7 | 1994 | |
| Pathogenicity | Molecular characterization of a plasmid-borne (pGT633) erythromycin resistance determinant (ermGT) from Lactobacillus reuteri 100-63. | Tannock GW, Luchansky JB, Miller L, Connell H, Thode-Andersen S, Mercer AA, Klaenhammer TR | Plasmid | 10.1006/plas.1994.1007 | 1994 | |
| Genetics | Lack of complete correlation between emetic and T-cell-stimulatory activities of staphylococcal enterotoxins. | Harris TO, Grossman D, Kappler JW, Marrack P, Rich RR, Betley MJ | Infect Immun | 10.1128/iai.61.8.3175-3183.1993 | 1993 | |
| Phenotype | Recombination at the coagulase locus in Staphylococcus aureus: plasmid integration and amplification. | McDevitt D, Wann ER, Foster TJ | J Gen Microbiol | 10.1099/00221287-139-4-695 | 1993 | |
| Pathogenicity | Toxicity of recombinant toxic shock syndrome toxin 1 and mutant toxins produced by Staphylococcus aureus in a rabbit infection model of toxic shock syndrome. | Bonventre PF, Heeg H, Cullen C, Lian CJ | Infect Immun | 10.1128/iai.61.3.793-799.1993 | 1993 | |
| Metabolism | Inducible erythromycin resistance in staphylococci is encoded by a member of the ATP-binding transport super-gene family. | Ross JI, Eady EA, Cove JH, Cunliffe WJ, Baumberg S, Wootton JC | Mol Microbiol | 10.1111/j.1365-2958.1990.tb00696.x | 1990 | |
| Enzymology | Characterisation and molecular cloning of the novel macrolide-streptogramin B resistance determinant from Staphylococcus epidermidis. | Ross JI, Farrell AM, Eady EA, Cove JH, Cunliffe WJ | J Antimicrob Chemother | 10.1093/jac/24.6.851 | 1989 | |
| Enzymology | Cloning and expression of the exfoliative toxin B gene from Staphylococcus aureus. | Jackson MP, Iandolo JJ | J Bacteriol | 10.1128/jb.166.2.574-580.1986 | 1986 | |
| Enzymology | Expression of a cloned Staphylococcus aureus alpha-hemolysin determinant in Bacillus subtilis and Staphylococcus aureus. | Fairweather N, Kennedy S, Foster TJ, Kehoe M, Dougan G | Infect Immun | 10.1128/iai.41.3.1112-1117.1983 | 1983 | |
| Pathogenicity | A Small Multihost Plasmid Carrying erm(T) Identified in Enterococcus faecalis. | Li XY, Yu R, Xu C, Shang Y, Li D, Du XD | Front Vet Sci | 10.3389/fvets.2022.850466 | 2022 | |
| Screening of Natural Molecules as Adjuvants to Topical Antibiotics to Treat Staphylococcus aureus from Diabetic Foot Ulcer Infections. | Oliveira D, Borges A, Saavedra MJ, Borges F, Simoes M | Antibiotics (Basel) | 10.3390/antibiotics11050620 | 2022 | ||
| Biotechnology | Horizontal Transfer of Bacteriocin Biosynthesis Genes Requires Metabolic Adaptation To Improve Compound Production and Cellular Fitness. | Krauss S, Harbig TA, Rapp J, Schaefle T, Franz-Wachtel M, Reetz L, Elsherbini AMA, Macek B, Grond S, Link H, Nieselt K, Krismer B, Peschel A, Heilbronner S | Microbiol Spectr | 10.1128/spectrum.03176-22 | 2022 | |
| An 11-year linezolid-resistant Staphylococcus capitis clone dissemination with a similar cfr-carrying plasmid in China. | Shen W, Chen J, Zhang R, Cai J | iScience | 10.1016/j.isci.2022.105644 | 2022 | ||
| Genetics | Hybrid assembly using long reads resolves repeats and completes the genome sequence of a laboratory strain of Staphylococcus aureus subsp. aureus RN4220. | Panthee S, Hamamoto H, Paudel A, Kaito C, Suzuki Y, Sekimizu K | Heliyon | 10.1016/j.heliyon.2022.e11376 | 2022 | |
| Pathogenicity | Breaking down antibiotic resistance in methicillin-resistant Staphylococcus aureus: Combining antimicrobial photodynamic and antibiotic treatments. | Willis JA, Cheburkanov V, Chen S, Soares JM, Kassab G, Blanco KC, Bagnato VS, de Figueiredo P, Yakovlev VV | Proc Natl Acad Sci U S A | 10.1073/pnas.2208378119 | 2022 | |
| Genetics | Bioinformatic Analysis of a Set of 14 Temperate Bacteriophages Isolated from Staphylococcus aureus Strains Highlights Their Massive Genetic Diversity. | Suarez CA, Carrasco ST, Brandolisio FNA, Abatangelo V, Boncompain CA, Peresutti-Bacci N, Morbidoni HR | Microbiol Spectr | 10.1128/spectrum.00334-22 | 2022 | |
| Pathogenicity | Antibacterial and Oxidative Stress-Protective Effects of Five Monoterpenes from Softwood. | Muilu-Makela R, Aapola U, Tienaho J, Uusitalo H, Sarjala T | Molecules | 10.3390/molecules27123891 | 2022 |
| #18922 | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 26309 |
| #20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 ) |
| #66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) . |
| #68375 | Automatically annotated from API ID32STA . |
| #125438 | Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 ) |
| #125439 | Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 . |
| #126262 | A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 ) |
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