Name: Staphylococcus aureus RN4220
Creator: BacDive
License: http://creativecommons.org/licenses/by-nc/4.0/

Strain identifier

BacDive ID: 23294

Type strain:

Species: Staphylococcus aureus

Strain Designation: RN4220

Culture col. no.: DSM 26309

Strain history: <- M. Mosa, IMUNA s.r.o., Praha, Czech Republic <- J. Doskar, Masaryk Univ., Faculty of Science, Brno, Czech Republic <- F. Götz, Univ. Tübingen <- R. P. Novick <- B. Kreisworth and S. Lofdahl

NCBI tax ID(s): 1280 (species)

SI-ID 405493

DSM 26309

Other strains from Staphylococcus aureus

Section

Staphylococcus aureus RN4220 is a mesophilic human pathogen that was isolated from laboratory research strain originally derived from NCTC 8325-4 using UV and chemical mutagenesis.

human pathogen
mesophilic
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	14-12-2023 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Bacillota*
	Class	*Bacilli*
	Order	*Caryophanales*
	Family	*Staphylococcaceae*
	Genus	*Staphylococcus*
	Species	**Staphylococcus aureus**
	Full Scientific Name (LPSN)	Staphylococcus aureus Rosenbach 1884 (Approved Lists 1980)

Synonym

Staphylococcus aureus subsp. anaerobius

Information on culture and growth conditions Culture and growth conditions

[Ref.: #18922]

Culture medium

TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)

[Ref.: #18922]

Culture medium growth

[Ref.: #18922]

Culture medium link

Medium recipe at MediaDive

[Ref.: #18922]

Culture medium composition

expand / minimize

	Temperatures	Kind of temperature		Temperature
[Ref.: #18922]			growth	37 °C

[Ref.: #18922]

Temperature range

mesophilic

Information on physiology and metabolism Physiology and metabolism

	Metabolite	Utilization activity	Kind of utilization tested
[Ref.: #68375]	arabinose ChEBI	-	fermentation	* from API ID32STA
[Ref.: #68375]	arginine ChEBI	+	hydrolysis	* from API ID32STA
[Ref.: #68375]	cellobiose ChEBI	-	fermentation	* from API ID32STA
[Ref.: #68375]	D-fructose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	D-glucose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	D-mannitol ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	D-mannose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	D-ribose ChEBI	-	fermentation	* from API ID32STA
[Ref.: #68375]	esculin ChEBI	-	hydrolysis	* from API ID32STA
[Ref.: #68375]	lactose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	maltose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	N-acetylglucosamine ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	nitrate ChEBI	+	reduction	* from API ID32STA
[Ref.: #68375]	ornithine ChEBI	-	degradation	* from API ID32STA
[Ref.: #68375]	raffinose ChEBI	-	fermentation	* from API ID32STA
[Ref.: #68375]	sucrose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	trehalose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	turanose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	urea ChEBI	-	hydrolysis	* from API ID32STA
	Only first 10 entries are displayed. Click here to see all.

	Antibiotica	Metabolite	Antibiotic resistance	Concentration
[Ref.: #68375]		novobiocin ChEBI	yes	1.8	µg	* from API ID32STA

	Metabolite production	Metabolite	Production
[Ref.: #68375]		acetoin ChEBI	yes	* from API ID32STA

	Physiological tests	Metabolite	Voges-Proskauer-test
[Ref.: #68375]		acetoin ChEBI	+	* from API ID32STA

	Enzyme	Enzyme activity	EC number
[Ref.: #68375]	alkaline phosphatase	+	3.1.3.1	* from API ID32STA
[Ref.: #68375]	arginine dihydrolase	+	3.5.3.6	* from API ID32STA
[Ref.: #68375]	beta-galactosidase	-	3.2.1.23	* from API ID32STA
[Ref.: #68375]	beta-glucosidase	-	3.2.1.21	* from API ID32STA
[Ref.: #68375]	beta-glucuronidase	-	3.2.1.31	* from API ID32STA
[Ref.: #68375]	L-arginine arylamidase	-		* from API ID32STA
[Ref.: #68375]	ornithine decarboxylase	-	4.1.1.17	* from API ID32STA
[Ref.: #68375]	pyrrolidonyl arylamidase	-	3.4.19.3	* from API ID32STA
[Ref.: #68375]	urease	-	3.5.1.5	* from API ID32STA

API® ID32STA:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Urease/urea hydrolysisURE	Arginine dihydrolaseADH (Arg)	Ornithine decarboxylaseODC	Esculin hydrolysisESC	Fermentation of D-glucoseGLU	Fermentation of D-fructoseFRU	Fermentation of D-mannoseMNE	Fermentation of maltoseMAL	Fermentation of lactoseLAC	Fermentation of trehaloseTRE	Fermentation of D-mannitolMAN	Fermentation of raffinoseRAF	Fermentation of D-riboseRIB	Fermentation of cellobioseCEL	Reduction of nitrateNIT	Acetoin production (Voges Proskauer test)VP	beta-Galactosidasebeta GAL	L-arginine arylamidaseArgA	Alkaline phosphatasePAL	Pyrrolidonyl arylamidasePyrA	Novobiocin resistanceNOVO	Fermentation of sucroseSAC	Fermentation of N-acetyl-glucosamineNAG	Fermentation of turanoseTUR	Fermentation of arabinoseARA	beta-Glucuronidasebeta GUR
[Ref.: #18922]	6177	-	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	-	+	+	+	+	-	-

Information on isolation source, the sampling and environmental conditions Isolation, sampling and environmental information

[Ref.: #18922]	Sample type/isolated from	laboratory research strain originally derived from NCTC 8325-4 using UV and chemical mutagenesis
* marker position based on {}

Isolation sources categories

#Engineered	#Laboratory	-
#Host	#Microbial	#Bacteria

What are isolation sources categories?

Information on possible application of the strain and its possible interaction with e.g. potential hosts Safety information

[Ref.: #18922]	Pathogenicity (human)	yes
[Ref.: #18922]	Pathogenicity (animal)	yes
[Ref.: #18922]	Biosafety level	2	Risk group (German classification) According to TRBA 466

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

Genome sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence accession description	Seq. accession number	Assembly level	Sequence database	Associated NCBI tax ID
[Ref.: #66792]	Staphylococcus aureus subsp. aureus RN4220 RN4220	GCA_018732165	complete	GenBank	561307 tax ID	*
[Ref.: #66792]	Staphylococcus aureus subsp. aureus RN4220	GCA_011751615	scaffold	GenBank	561307 tax ID	*
[Ref.: #66792]	Staphylococcus aureus subsp. aureus RN4220	GCA_000212435	contig	GenBank	561307 tax ID	*
[Ref.: #66792]	Staphylococcus aureus subsp. aureus RN4220	561307.24	complete	PATRIC	561307 tax ID	*
[Ref.: #66792]	Staphylococcus aureus subsp. aureus RN4220	561307.22	wgs	PATRIC	561307 tax ID	*
[Ref.: #66792]	Staphylococcus aureus subsp. aureus RN4220	561307.5	wgs	PATRIC	561307 tax ID	*

Data predicted using genome information as a basis Genome-based predictions

	Trait	Prediction	Confidence in %	In training data
	Predictions from Diaspora project based on: Staphylococcus aureus subsp. aureus RN4220 RN4220 NCBI: GCA_018732165.1
[Ref.: #69480]	flagellated	no	92.128	no
[Ref.: #69480]	gram-positive	yes	88.988	no
[Ref.: #69480]	anaerobic	no	99.508	no
[Ref.: #69480]	aerobic	yes	89.085	no
[Ref.: #69480]	halophile	yes	94.5	no
[Ref.: #69480]	spore-forming	no	93.424	no
[Ref.: #69480]	thermophile	no	99.688	no
[Ref.: #69480]	motile	no	90.356	no
[Ref.: #69480]	glucose-util	yes	87.555	no
[Ref.: #69480]	glucose-ferment	yes	86.048	no

Availability in culture collections External links

[Ref.: #18922]

Culture collection no.

DSM 26309

[Ref.: #87514]

SI-ID 405493

Literature:

Only first 10 entries are displayed. Click here to see all.

Topic	Title	Authors	Journal	DOI	Year
Metabolism	Novel Tet(L) Efflux Pump Variants Conferring Resistance to Tigecycline and Eravacycline in Staphylococcus Spp.	Wang N, Li D, Schwarz S, Qin S, Yao H, Du XD	Microbiol Spectr	10.1128/Spectrum.01310-21	2021	*
Enzymology	Multiplexed detection and differentiation of bacterial enzymes and bacteria by color-encoded sensor hydrogels.	Jia Z, Muller M, Le Gall T, Riool M, Muller M, Zaat SAJ, Montier T, Schonherr H	Bioact Mater	10.1016/j.bioactmat.2021.04.022	2021	*
Metabolism	N-terminal acetylation of antimicrobial peptide L163 improves its stability against protease degradation.	Li D, Yang Y, Li R, Huang L, Wang Z, Deng Q, Dong S	J Pept Sci	10.1002/psc.3337	2021	*
Pathogenicity	Inhibition of Staphylococcus aureus TetK and MsrA efflux pumps by hydroxyamines derived from lapachol and norlachol.	Figueredo FG, Parente RELT, Cavalcante-Figueredo MR, Figueiredo JG, da Silva RLP, Ferreira Matias EF, Silva TMS, Camara CA, de Morais Oliveira-Tintino CD, Tintino SR, Coutinho HDM, Fonteles MMF	J Bioenerg Biomembr	10.1007/s10863-021-09885-5	2021	*
Pathogenicity	Effect of estragole over the RN4220 Staphylococcus aureus strain and its toxicity in Drosophila melanogaster.	Bezerra AH, Bezerra SR, Macedo NS, de Sousa Silveira Z, Dos Santos Barbosa CR, de Freitas TS, Muniz DF, de Sousa Junior DL, Junior JPS, Donato IA, Coutinho HDM, da Cunha FAB	Life Sci	10.1016/j.lfs.2020.118675	2020	*
Genetics	Whole-genome sequence analyses of Glaesserella parasuis isolates reveals extensive genomic variation and diverse antibiotic resistance determinants.	Wan X, Li X, Osmundson T, Li C, Yan H	PeerJ	10.7717/peerj.9293	2020	*
Pathogenicity	MsrA Efflux Pump Inhibitory Activity of Piper cubeba L.f. and its Phytoconstituents against Staphylococcus aureus RN4220.	Ahirrao P, Tambat R, Chandal N, Mahey N, Kamboj A, Jain UK, Singh IP, Jachak SM, Nandanwar HS	Chem Biodivers	10.1002/cbdv.202000144	2020	*
Pathogenicity	Penicillin-binding protein PBP2a provides variable levels of protection toward different beta-lactams in Staphylococcus aureus RN4220.	Fergestad ME, Stamsas GA, Morales Angeles D, Salehian Z, Wasteson Y, Kjos M	Microbiologyopen	10.1002/mbo3.1057	2020	*
Metabolism	In Staphylococcus aureus, the Particulate State of the Cell Envelope Is Required for the Efficient Induction of Host Defense Responses.	Kim B, Jiang T, Bae JH, Yun HS, Jang SH, Kim JH, Kim JD, Hur JH, Shibata K, Kurokawa K, Jung Y, Peschel A, Bae T, Lee BL	Infect Immun	10.1128/IAI.00674-19	2019	*
Pathogenicity	Silviavirus phage MR003 displays a broad host range against methicillin-resistant Staphylococcus aureus of human origin.	Peng C, Hanawa T, Azam AH, LeBlanc C, Ung P, Matsuda T, Onishi H, Miyanaga K, Tanji Y	Appl Microbiol Biotechnol	10.1007/s00253-019-10039-2	2019	*
Pathogenicity	The tva(A) Gene from Brachyspira hyodysenteriae Confers Decreased Susceptibility to Pleuromutilins and Streptogramin A in Escherichia coli.	Garcia-Martin AB, Schwendener S, Perreten V	Antimicrob Agents Chemother	10.1128/AAC.00930-19	2019	*
Pathogenicity	Molecular characterization of multi-drug resistant coagulase negative cocci in non-hospital environment.	Nwibo DD, Panthee S, Hamamoto H, Sekimizu K	Drug Discov Ther	10.5582/ddt.2019.01031	2019	*
Pathogenicity	Capsaicin and gingerol analogues inhibit the growth of efflux-multidrug resistant bacteria and R-plasmids conjugal transfer.	Oyedemi BO, Kotsia EM, Stapleton PD, Gibbons S	J Ethnopharmacol	10.1016/j.jep.2019.111871	2019	*
Metabolism	Use of the counter selectable marker PheS* for genome engineering in Staphylococcus aureus.	Schuster CF, Howard SA, Grundling A	Microbiology (Reading)	10.1099/mic.0.000791	2019	*
Pathogenicity	Characterization of the Multi-Drug Resistance Gene cfr in Methicillin-Resistant Staphylococcus aureus (MRSA) Strains Isolated From Animals and Humans in China.	Li SM, Zhou YF, Li L, Fang LX, Duan JH, Liu FR, Liang HQ, Wu YT, Gu WQ, Liao XP, Sun J, Xiong YQ, Liu YH	Front Microbiol	10.3389/fmicb.2018.02925	2018	*
Metabolism	Intracellular Accumulation of Linezolid and Florfenicol in OptrA-Producing Enterococcus faecalis and Staphylococcus aureus.	Wang Y, Li X, Wang Y, Schwarz S, Shen J, Xia X	Molecules	10.3390/molecules23123195	2018	*
Enzymology	Isovalerylshikonin, a new resistance-modifying agent from Arnebia euchroma, supresses antimicrobial resistance of drug-resistant Staphylococcus aureus.	He JM, Sun SC, Sun ZL, Chen JT, Mu Q	Int J Antimicrob Agents	10.1016/j.ijantimicag.2018.08.021	2018	*
Metabolism	Changes in resistance to and antimicrobial activity of antibiotics during in vitro human digestion.	Lee SY, Kim OY, Yoon SY, Lee DY, Hur SJ	J Glob Antimicrob Resist	10.1016/j.jgar.2018.08.017	2018	*
Enzymology	Creation of deletion and insertion clonal complex 8 Staphylococcus aureus mutants using a common cloning vector.	Chen P, Karna SLR, Leung KP	J Microbiol Methods	10.1016/j.mimet.2018.05.008	2018	*
Pathogenicity	Biophysical evaluation of cardiolipin content as a regulator of the membrane lytic effect of antimicrobial peptides.	Hernandez-Villa L, Manrique-Moreno M, Leidy C, Jemiola-Rzeminska M, Ortiz C, Strzalka K	Biophys Chem	10.1016/j.bpc.2018.04.001	2018	*
Pathogenicity	Safe Staphylococcal Platform for the Development of Multivalent Nanoscale Vesicles against Viral Infections.	Yuan J, Yang J, Hu Z, Yang Y, Shang W, Hu Q, Zheng Y, Peng H, Zhang X, Cai X, Zhu J, Li M, Hu X, Zhou R, Rao X	Nano Lett	10.1021/acs.nanolett.7b03893	2018	*
Phenotype	Tannic acid affects the phenotype of Staphylococcus aureus resistant to tetracycline and erythromycin by inhibition of efflux pumps.	Tintino SR, Morais-Tintino CD, Campina FF, Costa MDS, Menezes IRA, de Matos YMLS, Calixto-Junior JT, Pereira PS, Siqueira-Junior JP, Leal-Balbino TC, Coutinho HDM, Balbino VQ	Bioorg Chem	10.1016/j.bioorg.2017.08.004	2017	*
Metabolism	The development of fluorescent protein tracing vectors for multicolor imaging of clinically isolated Staphylococcus aureus.	Kato F, Nakamura M, Sugai M	Sci Rep	10.1038/s41598-017-02930-7	2017	*
Pathogenicity	Inhibitory effects of flavonoids on biofilm formation by Staphylococcus aureus that overexpresses efflux protein genes.	Lopes LAA, Dos Santos Rodrigues JB, Magnani M, de Souza EL, de Siqueira-Junior JP	Microb Pathog	10.1016/j.micpath.2017.03.033	2017	*
Pathogenicity	Cholesterol and ergosterol affect the activity of Staphylococcus aureus antibiotic efflux pumps.	Tintino SR, Oliveira-Tintino CD, Campina FF, Costa MS, Cruz RP, Pereira RL, Andrade JC, Sousa EO, Siqueira-Junior JP, Coutinho HD, Leal-Balbino TC, Balbino VQ	Microb Pathog	10.1016/j.micpath.2017.01.019	2017	*
Metabolism	Dissecting the regulation of bile-induced biofilm formation in Staphylococcus aureus.	Ulluwishewa D, Wang L, Pereira C, Flynn S, Cain E, Stick S, Reen FJ, Ramsay JP, O'Gara F	Microbiology (Reading)	10.1099/mic.0.000317	2016	*
Pathogenicity	In vitro activity of human and animal cathelicidins against livestock-associated methicillin-resistant Staphylococcus aureus.	Blodkamp S, Kadlec K, Gutsmann T, Naim HY, von Kockritz-Blickwede M, Schwarz S	Vet Microbiol	10.1016/j.vetmic.2015.09.018	2015	*
Pathogenicity	Compounds in a particular production lot of tryptic soy broth inhibit Staphylococcus aureus cell growth.	Ishii M, Matsumoto Y, Sekimizu K	Drug Discov Ther	10.5582/ddt.2015.01030	2015	*
Enzymology	Complete Bypass of Restriction Systems for Major Staphylococcus aureus Lineages.	Monk IR, Tree JJ, Howden BP, Stinear TP, Foster TJ	mBio	10.1128/mBio.00308-15	2015	*
Pathogenicity	Detection of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates using a combination of delta-hemolysis assay and Etest.	Chang SC, Liu TP, Chen CJ, Lin LC, Lu JJ	Diagn Microbiol Infect Dis	10.1016/j.diagmicrobio.2014.12.006	2014	*
Enzymology	Enhancing DNA electro-transformation efficiency on a clinical Staphylococcus capitis isolate.	Cui B, Smooker PM, Rouch DA, Deighton MA	J Microbiol Methods	10.1016/j.mimet.2014.11.012	2014	*
Pathogenicity	Combating against methicillin-resistant Staphylococcus aureus - two fatty acids from Purslane (Portulaca oleracea L.) exhibit synergistic effects with erythromycin.	Chan BC, Han XQ, Lui SL, Wong CW, Wang TB, Cheung DW, Cheng SW, Ip M, Han SQ, Yang XS, Jolivalt C, Lau CB, Leung PC, Fung KP	J Pharm Pharmacol	10.1111/jphp.12315	2014	*
Phylogeny	The Staphylococcal Cassette Chromosome mec type V from Staphylococcus aureus ST398 is packaged into bacteriophage capsids.	Chlebowicz MA, Maslanova I, Kuntova L, Grundmann H, Pantucek R, Doskar J, van Dijl JM, Buist G	Int J Med Microbiol	10.1016/j.ijmm.2014.05.010	2014	*
Pathogenicity	Synthesis and antibacterial evaluation of amino acid-antibiotic conjugates.	Ibrahim MA, Panda SS, Birs AS, Serrano JC, Gonzalez CF, Alamry KA, Katritzky AR	Bioorg Med Chem Lett	10.1016/j.bmcl.2014.01.065	2014	*
Enzymology	Identification of the novel lincosamide resistance gene lnu(E) truncated by ISEnfa5-cfr-ISEnfa5 insertion in Streptococcus suis: de novo synthesis and confirmation of functional activity in Staphylococcus aureus.	Zhao Q, Wendlandt S, Li H, Li J, Wu C, Shen J, Schwarz S, Wang Y	Antimicrob Agents Chemother	10.1128/AAC.02007-13	2013	*
Pathogenicity	Flavonoids from Sophora moorcroftiana and their synergistic antibacterial effects on MRSA.	Wang SY, Sun ZL, Liu T, Gibbons S, Zhang WJ, Qing M	Phytother Res	10.1002/ptr.5098	2013	*
Genetics	Identification of a novel vga(E) gene variant that confers resistance to pleuromutilins, lincosamides and streptogramin A antibiotics in staphylococci of porcine origin.	Li J, Li B, Wendlandt S, Schwarz S, Wang Y, Wu C, Ma Z, Shen J	J Antimicrob Chemother	10.1093/jac/dkt482	2013	*
Genetics	Genetic variation in the Staphylococcus aureus 8325 strain lineage revealed by whole-genome sequencing.	Baek KT, Frees D, Renzoni A, Barras C, Rodriguez N, Manzano C, Kelley WL	PLoS One	10.1371/journal.pone.0077122	2013	*
Enzymology	Prevalence of fusB in Staphylococcus aureus clinical isolates.	Huang J, Ye M, Ding H, Guo Q, Ding B, Wang M	J Med Microbiol	10.1099/jmm.0.058305-0	2013	*
Pathogenicity	Novel erm(T)-carrying multiresistance plasmids from porcine and human isolates of methicillin-resistant Staphylococcus aureus ST398 that also harbor cadmium and copper resistance determinants.	Gomez-Sanz E, Kadlec K, Fessler AT, Zarazaga M, Torres C, Schwarz S	Antimicrob Agents Chemother	10.1128/AAC.00171-13	2013	*
Enzymology	Stably luminescent Staphylococcus aureus clinical strains for use in bioluminescent imaging.	Plaut RD, Mocca CP, Prabhakara R, Merkel TJ, Stibitz S	PLoS One	10.1371/journal.pone.0059232	2013	*
Metabolism	Synergistic effects of diosmetin with erythromycin against ABC transporter over-expressed methicillin-resistant Staphylococcus aureus (MRSA) RN4220/pUL5054 and inhibition of MRSA pyruvate kinase.	Chan BC, Ip M, Gong H, Lui SL, See RH, Jolivalt C, Fung KP, Leung PC, Reiner NE, Lau CB	Phytomedicine	10.1016/j.phymed.2013.02.007	2013	*
Enzymology	Detection and new genetic environment of the pleuromutilin-lincosamide-streptogramin A resistance gene lsa(E) in methicillin-resistant Staphylococcus aureus of swine origin.	Li B, Wendlandt S, Yao J, Liu Y, Zhang Q, Shi Z, Wei J, Shao D, Schwarz S, Wang S, Ma Z	J Antimicrob Chemother	10.1093/jac/dkt015	2013	*
Pathogenicity	Synthesis and antimicrobial evaluation of L-phenylalanine-derived C5-substituted rhodanine and chalcone derivatives containing thiobarbituric acid or 2-thioxo-4-thiazolidinone.	Jin X, Zheng CJ, Song MX, Wu Y, Sun LP, Li YJ, Yu LJ, Piao HR	Eur J Med Chem	10.1016/j.ejmech.2012.08.026	2012	*
Metabolism	The extracytoplasmic function sigma factor sigmaS protects against both intracellular and extracytoplasmic stresses in Staphylococcus aureus.	Miller HK, Carroll RK, Burda WN, Krute CN, Davenport JE, Shaw LN	J Bacteriol	10.1128/JB.00484-12	2012	*
Metabolism	Comparative expression analysis of two thermostable nuclease genes in Staphylococcus aureus.	Hu Y, Xie Y, Tang J, Shi X	Foodborne Pathog Dis	10.1089/fpd.2011.1033	2012	*
Pathogenicity	Direct and synergistic hemolysis caused by Staphylococcus phenol-soluble modulins: implications for diagnosis and pathogenesis.	Cheung GY, Duong AC, Otto M	Microbes Infect	10.1016/j.micinf.2011.11.013	2011	*
Metabolism	Genes involved in immunity to and secretion of aureocin A53, an atypical class II bacteriocin produced by Staphylococcus aureus A53.	Nascimento Jdos S, Coelho ML, Ceotto H, Potter A, Fleming LR, Salehian Z, Nes IF, Bastos Mdo C	J Bacteriol	10.1128/JB.06203-11	2011	*
Metabolism	Formylated peptides are important virulence factors in Staphylococcus aureus arthritis in mice.	Gjertsson I, Jonsson IM, Peschel A, Tarkowski A, Lindholm C	J Infect Dis	10.1093/infdis/jir713	2011	*
Metabolism	Lysis-deficient phages as novel therapeutic agents for controlling bacterial infection.	Paul VD, Sundarrajan S, Rajagopalan SS, Hariharan S, Kempashanaiah N, Padmanabhan S, Sriram B, Ramachandran J	BMC Microbiol	10.1186/1471-2180-11-195	2011	*
Metabolism	The minor groove-binding agent ELB-21 forms multiple interstrand and intrastrand covalent cross-links with duplex DNA and displays potent bactericidal activity against methicillin-resistant Staphylococcus aureus.	Rosado H, Rahman KM, Feuerbaum EA, Hinds J, Thurston DE, Taylor PW	J Antimicrob Chemother	10.1093/jac/dkr044	2011	*
Metabolism	Duckweed (Lemna minor) as a model plant system for the study of human microbial pathogenesis.	Zhang Y, Hu Y, Yang B, Ma F, Lu P, Li L, Wan C, Rayner S, Chen S	PLoS One	10.1371/journal.pone.0013527	2010	*
Metabolism	Characterization of a Staphylococcus aureus surface virulence factor that promotes resistance to oxidative killing and infectious endocarditis.	Malachowa N, Kohler PL, Schlievert PM, Chuang ON, Dunny GM, Kobayashi SD, Miedzobrodzki J, Bohach GA, Seo KS	Infect Immun	10.1128/IAI.00736-10	2010	*
Pathogenicity	Cloning and occurrence of czrC, a gene conferring cadmium and zinc resistance in methicillin-resistant Staphylococcus aureus CC398 isolates.	Cavaco LM, Hasman H, Stegger M, Andersen PS, Skov R, Fluit AC, Ito T, Aarestrup FM	Antimicrob Agents Chemother	10.1128/AAC.00058-10	2010	*
Enzymology	Wound healing properties and kill kinetics of Clerodendron splendens G. Don, a Ghanaian wound healing plant.	Gbedema SY, Emelia K, Francis A, Kofi A, Eric W	Pharmacognosy Res	10.4103/0974-8490.62948	2010	*
Metabolism	Glycosylation of wall teichoic acid in Staphylococcus aureus by TarM.	Xia G, Maier L, Sanchez-Carballo P, Li M, Otto M, Holst O, Peschel A	J Biol Chem	10.1074/jbc.M109.096172	2010	*
Pathogenicity	Activity of linezolid in an in vitro pharmacokinetic-pharmacodynamic model using different dosages and Staphylococcus aureus and Enterococcus faecalis strains with and without a hypermutator phenotype.	Ba BB, Arpin C, Bikie Bi Nso B, Dubois V, Saux MC, Quentin C	Antimicrob Agents Chemother	10.1128/AAC.01022-09	2010	*
Pathogenicity	Inhibition of Staphylococcus epidermidis biofilm formation by rabbit polyclonal antibodies against the SesC protein.	Shahrooei M, Hira V, Stijlemans B, Merckx R, Hermans PW, Van Eldere J	Infect Immun	10.1128/IAI.01464-08	2009	*
Enzymology	Inactivation of the SauI type I restriction-modification system is not sufficient to generate Staphylococcus aureus strains capable of efficiently accepting foreign DNA.	Veiga H, Pinho MG	Appl Environ Microbiol	10.1128/AEM.01862-08	2009	*
Metabolism	Antibiotics, arsenate and H2O2 induce the promoter of Staphylococcus aureus cspC gene more strongly than cold.	Chanda PK, Mondal R, Sau K, Sau S	J Basic Microbiol	10.1002/jobm.200800065	2009	*
Pathogenicity	Antibacterial, antioxidant and fibroblast growth stimulation of aqueous extracts of Ficus asperifolia Miq. and Gossypium arboreum L., wound-healing plants of Ghana.	Annan K, Houghton PJ	J Ethnopharmacol	10.1016/j.jep.2008.06.017	2008	*
Pathogenicity	Frequencies of resistance to Melaleuca alternifolia (tea tree) oil and rifampicin in Staphylococcus aureus, Staphylococcus epidermidis and Enterococcus faecalis.	Hammer KA, Carson CF, Riley TV	Int J Antimicrob Agents	10.1016/j.ijantimicag.2008.03.013	2008	*
Enzymology	Two thermostable nucleases coexisted in Staphylococcus aureus: evidence from mutagenesis and in vitro expression.	Tang J, Zhou R, Shi X, Kang M, Wang H, Chen H	FEMS Microbiol Lett	10.1111/j.1574-6968.2008.01194.x	2008	*
Transcriptome	Differences in potential for selection of clindamycin-resistant mutants between inducible erm(A) and erm(C) Staphylococcus aureus genes.	Daurel C, Huet C, Dhalluin A, Bes M, Etienne J, Leclercq R	J Clin Microbiol	10.1128/JCM.01925-07	2007	*
Pathogenicity	Detection of antistaphylococcal and toxic compounds by biological assay systems developed with a reporter Staphylococcus aureus strain harboring a heat inducible promoter - lacZ transcriptional fusion.	Chanda PK, Ganguly T, Das M, Lee CY, Luong TT, Sau S	J Biochem Mol Biol	10.5483/bmbrep.2007.40.6.936	2007	*
Pathogenicity	Role of hypermutability on bacterial fitness and emergence of resistance in experimental osteomyelitis due to Staphylococcus aureus.	Daurel C, Prunier AL, Chau F, Garry L, Leclercq R, Fantin B	FEMS Immunol Med Microbiol	10.1111/j.1574-695X.2007.00310.x	2007	*
Pathogenicity	Transduction of the plasmid encoding antiseptic resistance gene qacB in Staphylococcus aureus.	Nakaminami H, Noguchi N, Nishijima S, Kurokawa I, So H, Sasatsu M	Biol Pharm Bull	10.1248/bpb.30.1412	2007	*
Metabolism	Role of a qnr-like gene in the intrinsic resistance of Enterococcus faecalis to fluoroquinolones.	Arsene S, Leclercq R	Antimicrob Agents Chemother	10.1128/AAC.00274-07	2007	*
Pathogenicity	Specific Bifidobacterium strains isolated from elderly subjects inhibit growth of Staphylococcus aureus.	Lahtinen SJ, Jalonen L, Ouwehand AC, Salminen SJ	Int J Food Microbiol	10.1016/j.ijfoodmicro.2007.02.023	2007	*
Enzymology	Identification and characterization of nine novel types of small staphylococcal plasmids carrying the lincosamide nucleotidyltransferase gene lnu(A).	Luthje P, von Kockritz-Blickwede M, Schwarz S	J Antimicrob Chemother	10.1093/jac/dkm008	2007	*
Metabolism	Repression of Staphylococcus aureus SrrAB using inducible antisense srrA alters growth and virulence factor transcript levels.	Pragman AA, Ji Y, Schlievert PM	Biochemistry	10.1021/bi0603266	2007	*
Enzymology	Sau1: a novel lineage-specific type I restriction-modification system that blocks horizontal gene transfer into Staphylococcus aureus and between S. aureus isolates of different lineages.	Waldron DE, Lindsay JA	J Bacteriol	10.1128/JB.00418-06	2006	*
Enzymology	A novel antimicrobial epoxide isolated from larval Galleria mellonella infected by the nematode symbiont, Photorhabdus luminescens (Enterobacteriaceae).	Hu K, Li J, Li B, Webster JM, Chen G	Bioorg Med Chem	10.1016/j.bmc.2006.01.025	2006	*
Pathogenicity	A slipped-mispairing mutation in AgrA of laboratory strains and clinical isolates results in delayed activation of agr and failure to translate delta- and alpha-haemolysins.	Traber K, Novick R	Mol Microbiol	10.1111/j.1365-2958.2006.04986.x	2006	*
Genetics	Staphylococcal tetracycline-MLSB resistance plasmid pSTE2 is the product of an RSA-mediated in vivo recombination.	Hauschild T, Luthje P, Schwarz S	J Antimicrob Chemother	10.1093/jac/dki207	2005	*
Enzymology	Role of mutS and mutL genes in hypermutability and recombination in Staphylococcus aureus.	Prunier AL, Leclercq R	J Bacteriol	10.1128/JB.187.10.3455-3464.2005	2005	*
Enzymology	Sau42I, a BcgI-like restriction-modification system encoded by the Staphylococcus aureus quadruple-converting phage Phi42.	Dempsey RM, Carroll D, Kong H, Higgins L, Keane CT, Coleman DC	Microbiology (Reading)	10.1099/mic.0.27646-0	2005	*
Pathogenicity	Intravitreal human immune globulin in a rabbit model of Staphylococcus aureus toxin-mediated endophthalmitis: a potential adjunct in the treatment of endophthalmitis.	Han DP	Trans Am Ophthalmol Soc		2004	*
Pathogenicity	Enhanced resistance to erythromycin is conferred by the enterococcal msrC determinant in Staphylococcus aureus.	Reynolds E, Cove JH	J Antimicrob Chemother	10.1093/jac/dkh541	2005	*
Pathogenicity	Characterization of a bifunctional aminoglycoside-modifying enzyme with novel substrate specificity and its gene from a clinical isolate of methicillin-resistant Staphylococcus aureus with high arbekacin resistance.	Ishino K, Ishikawa J, Ikeda Y, Hotta K	J Antibiot (Tokyo)	10.7164/antibiotics.57.679	2004	*
Pathogenicity	Comparison of assays for detection of agents causing membrane damage in Staphylococcus aureus.	O'Neill AJ, Miller K, Oliva B, Chopra I	J Antimicrob Chemother	10.1093/jac/dkh476	2004	*
Phenotype	Bactericidal activity of quinupristin-dalfopristin against strains of Staphylococcus aureus with the MLS(B) phenotype of resistance according to the erm gene type.	Clarebout G, Nativelle E, Bozdogan B, Villers C, Leclercq R	Int J Antimicrob Agents	10.1016/j.ijantimicag.2004.06.016	2004	*
Metabolism	Intravitreally injected human immunoglobulin attenuates the effects of Staphylococcus aureus culture supernatant in a rabbit model of toxin-mediated endophthalmitis.	Perkins SL, Han DP, Burke JM, Schlievert PM, Wirostko WJ, Tarasewicz DG, Skumatz CM	Arch Ophthalmol	10.1001/archopht.122.10.1499	2004	*
Pathogenicity	Nucleotide sequence and organization of the multiresistance plasmid pSCFS1 from Staphylococcus sciuri.	Kehrenberg C, Ojo KK, Schwarz S	J Antimicrob Chemother	10.1093/jac/dkh457	2004	*
Pathogenicity	The cme gene of Clostridium difficile confers multidrug resistance in Enterococcus faecalis.	Lebel S, Bouttier S, Lambert T	FEMS Microbiol Lett	10.1016/j.femsle.2004.07.022	2004	*
Pathogenicity	Discarding multidrug resistance inducers, the possible role of a biosensing reporter in antimicrobial discovery.	Galluzzi L, Virtanen P, Karp M	Luminescence	10.1002/bio.771	2004	*
Metabolism	Low-proline environments impair growth, proline transport and in vivo survival of Staphylococcus aureus strain-specific putP mutants.	Schwan WR, Wetzel KJ, Gomez TS, Stiles MA, Beitlich BD, Grunwald S	Microbiology (Reading)	10.1099/mic.0.26710-0	2004	*
Pathogenicity	Inactivation of mprF affects vancomycin susceptibility in Staphylococcus aureus.	Ruzin A, Severin A, Moghazeh SL, Etienne J, Bradford PA, Projan SJ, Shlaes DM	Biochim Biophys Acta	10.1016/s0304-4165(03)00028-x	2003	*
Pathogenicity	Biflavonoids with cytotoxic and antibacterial activity from Ochna macrocalyx.	Tang S, Bremner P, Kortenkamp A, Schlage C, Gray AI, Gibbons S, Heinrich M	Planta Med	10.1055/s-2003-38478	2003	*
Pathogenicity	Molecular analysis of fusidic acid resistance in Staphylococcus aureus.	Besier S, Ludwig A, Brade V, Wichelhaus TA	Mol Microbiol	10.1046/j.1365-2958.2003.03307.x	2003	*
Pathogenicity	Characterization of a holin (HolNU3-1) in methicillin-resistant Staphylococcus aureus host.	Horii T, Suzuki Y, Kobayashi M	FEMS Immunol Med Microbiol	10.1111/j.1574-695X.2002.tb00638.x	2002	*
Pathogenicity	An elevated mutation frequency favors development of vancomycin resistance in Staphylococcus aureus.	Schaaff F, Reipert A, Bierbaum G	Antimicrob Agents Chemother	10.1128/AAC.46.11.3540-3548.2002	2002	*
Pathogenicity	Insertional inactivation of mutS in Staphylococcus aureus reveals potential for elevated mutation frequencies, although the prevalence of mutators in clinical isolates is low.	O'Neill AJ, Chopra I	J Antimicrob Chemother	10.1093/jac/dkf118	2002	*
Metabolism	Small-colony mutants of Staphylococcus aureus allow selection of gyrase-mediated resistance to dual-target fluoroquinolones.	Pan XS, Hamlyn PJ, Talens-Visconti R, Alovero FL, Manzo RH, Fisher LM	Antimicrob Agents Chemother	10.1128/AAC.46.8.2498-2506.2002	2002	*
Pathogenicity	Resistance to quinupristin-dalfopristin due to mutation of L22 ribosomal protein in Staphylococcus aureus.	Malbruny B, Canu A, Bozdogan B, Fantin B, Zarrouk V, Dutka-Malen S, Feger C, Leclercq R	Antimicrob Agents Chemother	10.1128/AAC.46.7.2200-2207.2002	2002	*
Cultivation	Genetic linkage between resistance to quaternary ammonium compounds and beta-lactam antibiotics in food-related Staphylococcus spp.	Sidhu MS, Heir E, Sorum H, Holck A	Microb Drug Resist	10.1089/10766290152773374	2001	*
Metabolism	Direct quantitation of the numbers of individual penicillin-binding proteins per cell in Staphylococcus aureus.	Pucci MJ, Dougherty TJ	J Bacteriol	10.1128/JB.184.2.588-591.2002	2002	*
Cultivation	Measurement of effects of antibiotics in bioluminescent Staphylococcus aureus RN4220.	Tenhami M, Hakkila K, Karp M	Antimicrob Agents Chemother	10.1128/AAC.45.12.3456-3461.2001	2001	*
Metabolism	Complementation of the essential peptidoglycan transpeptidase function of penicillin-binding protein 2 (PBP2) by the drug resistance protein PBP2A in Staphylococcus aureus.	Pinho MG, Filipe SR, de Lencastre H, Tomasz A	J Bacteriol	10.1128/JB.183.22.6525-6531.2001	2001	*
Metabolism	The Fbe (SdrG) protein of Staphylococcus epidermidis HB promotes bacterial adherence to fibrinogen.	Hartford O, O'Brien L, Schofield K, Wells J, Foster TJ	Microbiology (Reading)	10.1099/00221287-147-9-2545	2001	*
Pathogenicity	Phage conversion of Panton-Valentine leukocidin in Staphylococcus aureus: molecular analysis of a PVL-converting phage, phiSLT.	Narita S, Kaneko J, Chiba J, Piemont Y, Jarraud S, Etienne J, Kamio Y	Gene	10.1016/s0378-1119(01)00390-0	2001	*
Metabolism	Biosynthesis of the glycolipid anchor in lipoteichoic acid of Staphylococcus aureus RN4220: role of YpfP, the diglucosyldiacylglycerol synthase.	Kiriukhin MY, Debabov DV, Shinabarger DL, Neuhaus FC	J Bacteriol	10.1128/JB.183.11.3506-3514.2001	2001	*
Genetics	A method for demonstrating gene essentiality in Staphylococcus aureus.	Jana M, Luong TT, Komatsuzawa H, Shigeta M, Lee CY	Plasmid	10.1006/plas.2000.1473	2000	*
Pathogenicity	Effects of genes encoding resistance to streptogramins A and B on the activity of quinupristin-dalfopristin against Enterococcus faecium.	Bozdogan B, Leclercq R	Antimicrob Agents Chemother	10.1128/AAC.43.11.2720	1999	*
Enzymology	Transposition of IS1181 in the genomes of Staphylococcus and Listeria.	Chesneau O, Lailler R, Derbise A, El Solh N	FEMS Microbiol Lett	10.1111/j.1574-6968.1999.tb13718.x	1999	*
Enzymology	Activities of trovafloxacin compared with those of other fluoroquinolones against purified topoisomerases and gyrA and grlA mutants of Staphylococcus aureus.	Gootz TD, Zaniewski RP, Haskell SL, Kaczmarek FS, Maurice AE	Antimicrob Agents Chemother	10.1128/AAC.43.8.1845	1999	*
Genetics	Genetic analysis of the cap5 locus of Staphylococcus aureus.	Wann ER, Dassy B, Fournier JM, Foster TJ	FEMS Microbiol Lett	10.1111/j.1574-6968.1999.tb13360.x	1999	*
Pathogenicity	Luminescent bacterial sensor for cadmium and lead.	Tauriainen S, Karp M, Chang W, Virta M	Biosens Bioelectron	10.1016/s0956-5663(98)00027-x	1998	*
Enzymology	Effects of mutations in GrlA of topoisomerase IV from Staphylococcus aureus on quinolone and coumarin activity.	Fournier B, Hooper DC	Antimicrob Agents Chemother	10.1128/AAC.42.8.2109	1998	*
Pathogenicity	A new ketolide, HMR 3004, active against streptococci inducibly resistant to erythromycin.	Rosato A, Vicarini H, Bonnefoy A, Chantot JF, Leclercq R	Antimicrob Agents Chemother	10.1128/AAC.42.6.1392	1998	*
Enzymology	Penicillin-binding protein 1 of Staphylococcus aureus is essential for growth.	Wada A, Watanabe H	J Bacteriol	10.1128/JB.180.10.2759-2765.1998	1998	*
Enzymology	Recombinant luminescent bacteria for measuring bioavailable arsenite and antimonite.	Tauriainen S, Karp M, Chang W, Virta M	Appl Environ Microbiol	10.1128/aem.63.11.4456-4461.1997	1997	*
Pathogenicity	Quinolone susceptibility of norA-disrupted Staphylococcus aureus.	Yamada H, Kurose-Hamada S, Fukuda Y, Mitsuyama J, Takahata M, Minami S, Watanabe Y, Narita H	Antimicrob Agents Chemother	10.1128/AAC.41.10.2308	1997	*
Enzymology	Purification of Staphylococcus aureus beta-toxin: comparison of three isoelectric focusing methods.	Gaskin DK, Bohach GA, Schlievert PM, Hovde CJ	Protein Expr Purif	10.1006/prep.1996.0664	1997	*
Phenotype	Minimal functional system required for expression of erythromycin resistance by msrA in Staphylococcus aureus RN4220.	Ross JI, Eady EA, Cove JH, Baumberg S	Gene	10.1016/s0378-1119(96)00541-0	1996	*
Enzymology	Purification and partial characterization of a novel antibacterial agent (Bac1829) Produced by Staphylococcus aureus KSI1829.	Crupper SS, Iandolo JJ	Appl Environ Microbiol	10.1128/aem.62.9.3171-3175.1996	1996	*
Genetics	Alterations in the DNA topoisomerase IV grlA gene responsible for quinolone resistance in Staphylococcus aureus.	Yamagishi J, Kojima T, Oyamada Y, Fujimoto K, Hattori H, Nakamura S, Inoue M	Antimicrob Agents Chemother	10.1128/AAC.40.5.1157	1996	*
Phenotype	Suppression of the thermosensitive replication phenotype of the derivative plasmid of pI9789::Tn552 in Staphylococcus aureus may involve integration of the plasmid into the host chromosome.	Sohail M, Dyke KG	FEMS Microbiol Lett	10.1111/j.1574-6968.1996.tb08038.x	1996	*
Enzymology	Analysis of gyrA and grlA mutations in stepwise-selected ciprofloxacin-resistant mutants of Staphylococcus aureus.	Ferrero L, Cameron B, Crouzet J	Antimicrob Agents Chemother	10.1128/AAC.39.7.1554	1995	*
Metabolism	The lysostaphin endopeptidase resistance gene (epr) specifies modification of peptidoglycan cross bridges in Staphylococcus simulans and Staphylococcus aureus.	DeHart HP, Heath HE, Heath LS, LeBlanc PA, Sloan GL	Appl Environ Microbiol	10.1128/aem.61.4.1475-1479.1995	1995	*
Enzymology	A genetic and molecular characterization of the recA gene from Staphylococcus aureus.	Bayles KW, Brunskill EW, Iandolo JJ, Hruska LL, Huang S, Pattee PA, Smiley BK, Yasbin RE	Gene	10.1016/0378-1119(94)90033-7	1994	*
Pathogenicity	Molecular characterization of a plasmid-borne (pGT633) erythromycin resistance determinant (ermGT) from Lactobacillus reuteri 100-63.	Tannock GW, Luchansky JB, Miller L, Connell H, Thode-Andersen S, Mercer AA, Klaenhammer TR	Plasmid	10.1006/plas.1994.1007	1994	*
Genetics	Lack of complete correlation between emetic and T-cell-stimulatory activities of staphylococcal enterotoxins.	Harris TO, Grossman D, Kappler JW, Marrack P, Rich RR, Betley MJ	Infect Immun	10.1128/iai.61.8.3175-3183.1993	1993	*
Phenotype	Recombination at the coagulase locus in Staphylococcus aureus: plasmid integration and amplification.	McDevitt D, Wann ER, Foster TJ	J Gen Microbiol	10.1099/00221287-139-4-695	1993	*
Pathogenicity	Toxicity of recombinant toxic shock syndrome toxin 1 and mutant toxins produced by Staphylococcus aureus in a rabbit infection model of toxic shock syndrome.	Bonventre PF, Heeg H, Cullen C, Lian CJ	Infect Immun	10.1128/iai.61.3.793-799.1993	1993	*
Metabolism	Inducible erythromycin resistance in staphylococci is encoded by a member of the ATP-binding transport super-gene family.	Ross JI, Eady EA, Cove JH, Cunliffe WJ, Baumberg S, Wootton JC	Mol Microbiol	10.1111/j.1365-2958.1990.tb00696.x	1990	*
Enzymology	Characterisation and molecular cloning of the novel macrolide-streptogramin B resistance determinant from Staphylococcus epidermidis.	Ross JI, Farrell AM, Eady EA, Cove JH, Cunliffe WJ	J Antimicrob Chemother	10.1093/jac/24.6.851	1989	*
Enzymology	Cloning and expression of the exfoliative toxin B gene from Staphylococcus aureus.	Jackson MP, Iandolo JJ	J Bacteriol	10.1128/jb.166.2.574-580.1986	1986	*
Enzymology	Expression of a cloned Staphylococcus aureus alpha-hemolysin determinant in Bacillus subtilis and Staphylococcus aureus.	Fairweather N, Kennedy S, Foster TJ, Kehoe M, Dougan G	Infect Immun	10.1128/iai.41.3.1112-1117.1983	1983	*
Pathogenicity	A Small Multihost Plasmid Carrying erm(T) Identified in Enterococcus faecalis.	Li XY, Yu R, Xu C, Shang Y, Li D, Du XD	Front Vet Sci	10.3389/fvets.2022.850466	2022	*
Biotechnology	Horizontal Transfer of Bacteriocin Biosynthesis Genes Requires Metabolic Adaptation To Improve Compound Production and Cellular Fitness.	Krauss S, Harbig TA, Rapp J, Schaefle T, Franz-Wachtel M, Reetz L, Elsherbini AMA, Macek B, Grond S, Link H, Nieselt K, Krismer B, Peschel A, Heilbronner S	Microbiol Spectr	10.1128/spectrum.03176-22	2022	*
Genetics	Hybrid assembly using long reads resolves repeats and completes the genome sequence of a laboratory strain of Staphylococcus aureus subsp. aureus RN4220.	Panthee S, Hamamoto H, Paudel A, Kaito C, Suzuki Y, Sekimizu K	Heliyon	10.1016/j.heliyon.2022.e11376	2022	*
Pathogenicity	Breaking down antibiotic resistance in methicillin-resistant Staphylococcus aureus: Combining antimicrobial photodynamic and antibiotic treatments.	Willis JA, Cheburkanov V, Chen S, Soares JM, Kassab G, Blanco KC, Bagnato VS, de Figueiredo P, Yakovlev VV	Proc Natl Acad Sci U S A	10.1073/pnas.2208378119	2022	*
Genetics	Bioinformatic Analysis of a Set of 14 Temperate Bacteriophages Isolated from Staphylococcus aureus Strains Highlights Their Massive Genetic Diversity.	Suarez CA, Carrasco ST, Brandolisio FNA, Abatangelo V, Boncompain CA, Peresutti-Bacci N, Morbidoni HR	Microbiol Spectr	10.1128/spectrum.00334-22	2022	*
Pathogenicity	Antibacterial and Oxidative Stress-Protective Effects of Five Monoterpenes from Softwood.	Muilu-Makela R, Aapola U, Tienaho J, Uusitalo H, Sarjala T	Molecules	10.3390/molecules27123891	2022	*
	Hypericin and Pheophorbide a Mediated Photodynamic Therapy Fighting MRSA Wound Infections: A Translational Study from In Vitro to In Vivo.	Chan BCL, Dharmaratne P, Wang B, Lau KM, Lee CC, Cheung DWS, Chan JYW, Yue GGL, Lau CBS, Wong CK, Fung KP, Ip M	Pharmaceutics	10.3390/pharmaceutics13091399	2021	*
	Identification of the Multiresistance Gene poxtA in Oxazolidinone-Susceptible Staphylococcus haemolyticus and Staphylococcus saprophyticus of Pig and Feed Origins.	Chen L, Hu JX, Liu C, Liu J, Ma ZB, Tang ZY, Li YF, Zeng ZL	Pathogens	10.3390/pathogens10050601	2021	*
	ROS induces NETosis by oxidizing DNA and initiating DNA repair.	Azzouz D, Khan MA, Palaniyar N	Cell Death Discov	10.1038/s41420-021-00491-3	2021	*
	The Role of Amino Acid Substitution in HepT Toward Menaquinone Isoprenoid Chain Length Definition and Lysocin E Sensitivity in Staphylococcus aureus.	Panthee S, Paudel A, Hamamoto H, Uhlemann AC, Sekimizu K	Front Microbiol	10.3389/fmicb.2020.02076	2020	*
	A class A beta-lactamase produced by borderline oxacillin-resistant Staphylococcus aureus hydrolyses oxacillin.	Nomura R, Nakaminami H, Takasao K, Muramatsu S, Kato Y, Wajima T, Noguchi N	J Glob Antimicrob Resist	10.1016/j.jgar.2020.03.002	2020	*
	Construction of Stable Fluorescent Reporter Plasmids for Use in Staphylococcus aureus.	Rodriguez MD, Paul Z, Wood CE, Rice KC, Triplett EW	Front Microbiol	10.3389/fmicb.2017.02491	2017	*
	Efficient transformation of Staphylococcus aureus using multi-pulse electroporation.	Hisatsune J, Sato'o Y, Yu L, Kutsuno S, Hayakawa Y, Sugai M	J Microbiol Methods	10.1016/j.mimet.2016.08.012	2016	*
	Action of cholecalciferol and alpha-tocopherol on Staphylococcus aureus efflux pumps.	Tintino SR, Morais-Tintino CD, Campina FF, Pereira RL, Costa Mdo S, Braga MF, Limaverde PW, Andrade JC, Siqueira-Junior JP, Coutinho HD, Balbino VQ, Leal-Balbino TC, Ribeiro-Filho J, Quintans-Junior LJ	EXCLI J	10.17179/excli2016-277	2016	*
	Synthesis, characterization and biological evaluation of a new photoactive hydrogel against Gram-positive and Gram-negative bacteria.	Spagnul C, Greenman J, Wainwright M, Kamil Z, Boyle RW	J Mater Chem B	10.1039/c5tb02569a	2016	*
	The Essential WalK Histidine Kinase and WalR Regulator Differentially Mediate Autolysis of Staphylococcus aureus RN4220.	Zheng L, Yan M, Fan F, Ji Y	J Nat Sci		2015	*
	Effect of disruption of Staphylococcus aureus PBP4 gene on resistance to beta-lactam antibiotics.	Katayama Y, Zhang HZ, Chambers HF	Microb Drug Resist	10.1089/107662903322762752	2003	*
	Osmoadaptation by Staphylococcus aureus : Analysis of Several Strains Linked to Food Poisoning Outbreaks.	Louch HA, Eck ML, Miller KJ	J Food Prot	10.4315/0362-028X-60.2.139	1997	*
	Screening of Natural Molecules as Adjuvants to Topical Antibiotics to Treat Staphylococcus aureus from Diabetic Foot Ulcer Infections.	Oliveira D, Borges A, Saavedra MJ, Borges F, Simoes M	Antibiotics (Basel)	10.3390/antibiotics11050620	2022	*
	An 11-year linezolid-resistant Staphylococcus capitis clone dissemination with a similar cfr-carrying plasmid in China.	Shen W, Chen J, Zhang R, Cai J	iScience	10.1016/j.isci.2022.105644	2022	*

References

#18922

Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 26309

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#66792

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#68375

Automatically annotated from API ID32STA .

#69480

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#87514

Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.: StrainInfo: A central database for resolving microbial strain identifiers . ( DOI 10.60712/SI-ID405493.1 )

* These data were automatically processed and therefore are not curated

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