Staphylococcus aureus (DSM 11823, ICB 25004)
Staphylococcus aureus DSM 11823 is a human pathogen that was isolated from clinical material.
human pathogen BacteriaName and taxonomic classification
| @ref 20215 |
Last LPSN update
2026-05-29 08:28:17 |
| Domain Bacteria |
| Phylum Bacillota |
| Class Bacilli |
| Order Caryophanales |
| Family Staphylococcaceae |
| Genus Staphylococcus |
| Species Staphylococcus aureus |
| Full scientific name Staphylococcus aureus Rosenbach 1884 (Approved Lists 1980) |
| Synonyms (2) |
Culture and growth conditions
Culture medium
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 4504 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | Medium recipe at MediaDive  | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base | ||
| 4504 | TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) | Medium recipe at MediaDive | Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water |
Culture temp
| @ref | Growth | Type | Temperature (°C) | |
|---|---|---|---|---|
| 4504 | positive | growth | 37 |
Physiology and metabolism
Antibiotic susceptibility testing
| Test 1 | |
|---|---|
| @ref | 4504 |
| Medium | Müller-Hinton Agar |
| Manual annotation | 1 |
| Inhibition zone diameter in mm | |
| Amikacin 30µg (disc) | 28 |
| Ampicillin 10µg (disc) | 44 |
| Aztreonam 30µg (disc) | 0 |
| Cefiderocol 30µg (disc) | 16 |
| Cefotaxime 30µg (disc) | 32-34 |
| Ceftazidime 10µg (disc) | 20 |
| Ceftriaxone 30µg (disc) | 30 |
| Chloramphenicol 30µg (disc) | 30 |
| Ciprofloxacin 5µg (disc) | 36 |
| Clindamycin 10µg (disc) | 36 |
| Colistin sulphate 10µg (disc) | 0 |
| Erythromycin 15µg (disc) | 32 |
| Fosfomycin 50µg (disc) | 50 |
| Gentamicin 30µg (disc) | 28 |
| Imipenem 10µg (disc) | 50 |
| Kanamycin 30µg (disc) | 28 |
| Levofloxacin 5µg (disc) | 36 |
| Linezolid 10µg (disc) | 36-38 |
| Meropenem 10µg (disc) | 40 |
| Moxifloxacin 5µg (disc) | 40 |
| Nitrofurantoin 100µg (disc) | 22 |
| Ofloxacin 5µg (disc) | 32 |
| Oxacillin 5µg (disc) | 36 |
| Penicillin G 6µg (disc) | 44-46 |
| Piperacillin/Tazobactam 110µg (disc) | 44 |
| Polymyxin B 300Unit | 12 |
| Quinupristin/Dalfopristin 15µg (disc) | 28-30 |
| Rifampicin 5µg (disc) | 36 |
| Teicoplanin 30µg (disc) | 18 |
| Tetracycline 30µg (disc) | 36 |
| Ticarcillin 75µg (disc) | 50 |
| Tigecycline 15µg (disc) | 30-32 |
| Trimethoprim-sulfamethoxazole (1:19) 10µg (disc) | 34 |
| Vancomycin 30µg (disc) | 20 |
Metabolite utilization
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68375 | 22599 ChEBI | arabinose | - | fermentation | from API ID32STA |
| 68375 | 29016 ChEBI | arginine | + | hydrolysis | from API ID32STA |
| 68375 | 17057 ChEBI | cellobiose | - | fermentation | from API ID32STA |
| 68375 | 15824 ChEBI | D-fructose | + | fermentation | from API ID32STA |
| 68375 | 17634 ChEBI | D-glucose | + | fermentation | from API ID32STA |
| 68375 | 16899 ChEBI | D-mannitol | + | fermentation | from API ID32STA |
| 68375 | 16024 ChEBI | D-mannose | + | fermentation | from API ID32STA |
| 68375 | 16988 ChEBI | D-ribose | - | fermentation | from API ID32STA |
| 68375 | 4853 ChEBI | esculin | - | hydrolysis | from API ID32STA |
| 68375 | 17716 ChEBI | lactose | + | fermentation | from API ID32STA |
| 68375 | 17306 ChEBI | maltose | + | fermentation | from API ID32STA |
| 68375 | 59640 ChEBI | N-acetylglucosamine | + | fermentation | from API ID32STA |
| 68375 | 17632 ChEBI | nitrate | + | reduction | from API ID32STA |
| 68375 | 18257 ChEBI | ornithine | - | degradation | from API ID32STA |
| 68375 | 17992 ChEBI | sucrose | + | fermentation | from API ID32STA |
| 68375 | 27082 ChEBI | trehalose | + | fermentation | from API ID32STA |
| 68375 | 32528 ChEBI | turanose | + | fermentation | from API ID32STA |
| 68375 | 16199 ChEBI | urea | + | hydrolysis | from API ID32STA |
Antibiotic resistance
| @ref | ChEBI | Metabolite | Is resistant | Resistance conc. | |
|---|---|---|---|---|---|
| 4504 | 161680 | Aztreonam | 30 µg (disc) | from Antibiotic test | |
| 4504 | 37943 | Colistin sulphate | 10 µg (disc) | from Antibiotic test |
Enzymes
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68375 | alkaline phosphatase | + | 3.1.3.1 | from API ID32STA |
| 68375 | arginine dihydrolase | + | 3.5.3.6 | from API ID32STA |
| 68375 | beta-glucosidase | - | 3.2.1.21 | from API ID32STA |
| 68375 | beta-glucuronidase | - | 3.2.1.31 | from API ID32STA |
| 68375 | L-arginine arylamidase | - | from API ID32STA | |
| 68375 | ornithine decarboxylase | - | 4.1.1.17 | from API ID32STA |
| 68375 | pyrrolidonyl arylamidase | - | 3.4.19.3 | from API ID32STA |
| 68375 | urease | + | 3.5.1.5 | from API ID32STA |
API ID32STA
| @ref | URE | ADH (Arg) | ODC | ESC | GLU | FRU | MNE | MAL | LAC | TRE | MAN | RAF | RIB | CEL | Reduction of nitrateNIT | Acetoin production (Voges Proskauer test)VP | beta GAL | L-arginine arylamidaseArgA | PAL | Pyrrolidonyl arylamidasePyrA | NOVO | SAC | NAG | TUR | ARA | beta GUR | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4504 | + | + | - | - | + | + | + | + | + | + | + | - | - | - | + | +/- | +/- | - | + | - | + | + | + | + | - | - | |
| 4504 | + | + | - | - | + | + | + | + | + | + | + | +/- | - | - | + | + | - | - | + | - | - | + | + | + | - | - |
Literature
Literature 
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Biotechnology | Validation of the Peel Plate Staphylococcus Aureus (SA) Test for Enumeration of S. aureus in Selected Foods and Non-Cultured Dairy Products: AOAC Performance Tested MethodSM 082401. | Salter RS, Durbin GW, Li S, Gilbert M, Crowley ES, Deterding A, Bastin B. | J AOAC Int | 10.1093/jaoacint/qsae083 | 2025 | |
| The skin microbiome stratifies patients with cutaneous T cell lymphoma and determines event-free survival. | Licht P, Dominelli N, Kleemann J, Pastore S, Muller ES, Haist M, Hartmann KS, Stege H, Bros M, Meissner M, Grabbe S, Heermann R, Mailander V. | NPJ Biofilms Microbiomes | 10.1038/s41522-024-00542-4 | 2024 | | |
| Molecular Profiling of Keratinocyte Skin Tumors Links Staphylococcus aureus Overabundance and Increased Human beta-Defensin-2 Expression to Growth Promotion of Squamous Cell Carcinoma. | Madhusudhan N, Pausan MR, Halwachs B, Durdevic M, Windisch M, Kehrmann J, Patra V, Wolf P, Boukamp P, Moissl-Eichinger C, Cerroni L, Becker JC, Gorkiewicz G. | Cancers (Basel) | 10.3390/cancers12030541 | 2020 | | |
| Pathogenicity | Comparative mutant prevention concentrations of pradofloxacin and other veterinary fluoroquinolones indicate differing potentials in preventing selection of resistance. | Wetzstein HG. | Antimicrob Agents Chemother | 10.1128/aac.49.10.4166-4173.2005 | 2005 | |
| Enzymology | Highly Effective Inhibition of Biofilm Formation by the First Metagenome-Derived AI-2 Quenching Enzyme. | Weiland-Brauer N, Kisch MJ, Pinnow N, Liese A, Schmitz RA. | Front Microbiol | 10.3389/fmicb.2016.01098 | 2016 | |
How to cite
If you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive14462.20260601.11
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain dataIsabel Schober, Julia Koblitz, Joaquim Sardà Carbasse, Christian Ebeling, Marvin Leon Schmidt, Adam Podstawka, Rohit Gupta, Vinodh Ilangovan, Javad Chamanara, Jörg Overmann, Lorenz Christian Reimer
Nucleic Acids Research; database issue 2025.
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