Name: Staphylococcus aureus DSM 6247
Creator: BacDive
License: https://creativecommons.org/licenses/by/4.0/

Strain identifier

BacDive ID: 14456

Type strain:

Species: Staphylococcus aureus

Culture col. no.: DSM 6247, CCM 2524, IMET 10760, CCUG 52423, CNCTC Mau 43/60, SG 511

Strain history: <- IMET <- H. Knöll <- Serol. Bakt. Abt. IG Farben, Höchst, SG 511

NCBI tax ID(s): 1280 (species)

SI-ID 48129

DSM 6247, CCM 2524, IMET 10760, CCUG 52423, CNCTC 5497

Special Collections

DSMZ
CCUG

Other strains from Staphylococcus aureus

Staphylococcus aureus DSM 6247 is an aerobe human pathogen of the family Staphylococcaceae.

aerobe
human pathogen
Bacteria

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	14-12-2023 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Bacillota*
	Class	*Bacilli*
	Order	*Caryophanales*
	Family	*Staphylococcaceae*
	Genus	*Staphylococcus*
	Species	**Staphylococcus aureus**
	Full Scientific Name (LPSN)	Staphylococcus aureus Rosenbach 1884 (Approved Lists 1980)

Synonym

Staphylococcus aureus subsp. anaerobius

Information on culture and growth conditions Culture and growth conditions

[Ref.: #2554]

Culture medium

TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)

[Ref.: #2554]

Culture medium growth

[Ref.: #2554]

Culture medium link

Medium recipe at MediaDive

[Ref.: #2554]

Culture medium composition

expand / minimize

	Temperatures	Kind of temperature		Temperature
[Ref.: #2554]			growth	37 °C
[Ref.: #59547]			growth	37 °C

Information on physiology and metabolism Physiology and metabolism

[Ref.: #59547]

Oxygen tolerance

aerobe

	Metabolite	Utilization activity	Kind of utilization tested
[Ref.: #68375]	arabinose ChEBI	-	fermentation	* from API ID32STA
[Ref.: #68375]	arginine ChEBI	+	hydrolysis	* from API ID32STA
[Ref.: #68375]	cellobiose ChEBI	-	fermentation	* from API ID32STA
[Ref.: #68375]	D-fructose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	D-glucose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	D-mannitol ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	D-mannose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	esculin ChEBI	-	hydrolysis	* from API ID32STA
[Ref.: #68375]	lactose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	maltose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	N-acetylglucosamine ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	nitrate ChEBI	+	reduction	* from API ID32STA
[Ref.: #68375]	ornithine ChEBI	-	degradation	* from API ID32STA
[Ref.: #68375]	raffinose ChEBI	-	fermentation	* from API ID32STA
[Ref.: #68375]	sucrose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	trehalose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	turanose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	urea ChEBI	+	hydrolysis	* from API ID32STA
	Only first 10 entries are displayed. Click here to see all.

	Metabolite production	Metabolite	Production
[Ref.: #68375]		acetoin ChEBI	yes	* from API ID32STA

	Physiological tests	Metabolite	Voges-Proskauer-test
[Ref.: #68375]		acetoin ChEBI	+	* from API ID32STA

	Enzyme	Enzyme activity	EC number
[Ref.: #68375]	alkaline phosphatase	+	3.1.3.1	* from API ID32STA
[Ref.: #68375]	arginine dihydrolase	+	3.5.3.6	* from API ID32STA
[Ref.: #68375]	beta-galactosidase	-	3.2.1.23	* from API ID32STA
[Ref.: #68375]	beta-glucosidase	-	3.2.1.21	* from API ID32STA
[Ref.: #68375]	beta-glucuronidase	-	3.2.1.31	* from API ID32STA
[Ref.: #68375]	L-arginine arylamidase	-		* from API ID32STA
[Ref.: #68375]	ornithine decarboxylase	-	4.1.1.17	* from API ID32STA
[Ref.: #68375]	pyrrolidonyl arylamidase	-	3.4.19.3	* from API ID32STA
[Ref.: #68375]	urease	+	3.5.1.5	* from API ID32STA

API® ID32STA:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Urease/urea hydrolysisURE	Arginine dihydrolaseADH (Arg)	Ornithine decarboxylaseODC	Esculin hydrolysisESC	Fermentation of D-glucoseGLU	Fermentation of D-fructoseFRU	Fermentation of D-mannoseMNE	Fermentation of maltoseMAL	Fermentation of lactoseLAC	Fermentation of trehaloseTRE	Fermentation of D-mannitolMAN	Fermentation of raffinoseRAF	Fermentation of D-riboseRIB	Fermentation of cellobioseCEL	Reduction of nitrateNIT	Acetoin production (Voges Proskauer test)VP	beta-Galactosidasebeta GAL	L-arginine arylamidaseArgA	Alkaline phosphatasePAL	Pyrrolidonyl arylamidasePyrA	Novobiocin resistanceNOVO	Fermentation of sucroseSAC	Fermentation of N-acetyl-glucosamineNAG	Fermentation of turanoseTUR	Fermentation of arabinoseARA	beta-Glucuronidasebeta GUR
[Ref.: #59547]	2359	+	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	-	-	+	+	+	-	-
[Ref.: #2554]	5813	+	+	-	-	+	+	+	+	+	+	+	-	+	-	+	+	-	-	+	-	+	+	+	+	-	-

Information on possible application of the strain and its possible interaction with e.g. potential hosts Safety information

[Ref.: #2554]	Pathogenicity (human)	yes
[Ref.: #2554]	Pathogenicity (animal)	yes
[Ref.: #2554]	Biosafety level	2	Risk group (German classification) According to TRBA 466

Availability in culture collections External links

[Ref.: #2554]

Culture collection no.

DSM 6247, CCM 2524, IMET 10760, CCUG 52423, CNCTC Mau 43/60, SG 511

[Ref.: #83597]

SI-ID 48129

Literature:

Only first 10 entries are displayed. Click here to see all.

	Title	Authors	Journal	DOI	Year
Metabolism	A plant endophyte Staphylococcus hominis strain MBL_AB63 produces a novel lantibiotic, homicorcin and a position one variant.	Aftab Uddin M, Akter S, Ferdous M, Haidar B, Amin A, Shofiul Islam Molla AHM, Khan H, Islam MR	Sci Rep	10.1038/s41598-021-90613-9	2021	*
Genetics	Differential daptomycin resistance development in Staphylococcus aureus strains with active and mutated gra regulatory systems.	Muller A, Grein F, Otto A, Gries K, Orlov D, Zarubaev V, Girard M, Sher X, Shamova O, Roemer T, Francois P, Becher D, Schneider T, Sahl HG	Int J Med Microbiol	10.1016/j.ijmm.2017.12.002	2017	*
Metabolism	Structural Basis for Xenosiderophore Utilization by the Human Pathogen Staphylococcus aureus.	Endicott NP, Lee E, Wencewicz TA	ACS Infect Dis	10.1021/acsinfecdis.7b00036	2017	*
Pathogenicity	Development of in vitro resistance to chitosan is related to changes in cell envelope structure of Staphylococcus aureus.	Raafat D, Leib N, Wilmes M, Francois P, Schrenzel J, Sahl HG	Carbohydr Polym	10.1016/j.carbpol.2016.09.075	2016	*
Metabolism	Trihydroxamate siderophore-fluoroquinolone conjugates are selective sideromycin antibiotics that target Staphylococcus aureus.	Wencewicz TA, Long TE, Mollmann U, Miller MJ	Bioconjug Chem	10.1021/bc300610f	2013	*
Pathogenicity	Antimicrobial phenalenone derivatives from the marine-derived fungus Coniothyrium cereale.	Elsebai MF, Kehraus S, Lindequist U, Sasse F, Shaaban S, Gutschow M, Josten M, Sahl HG, Konig GM	Org Biomol Chem	10.1039/c0ob00625d	2010	*
Genetics	Native graS mutation supports the susceptibility of Staphylococcus aureus strain SG511 to antimicrobial peptides.	Sass P, Bierbaum G	Int J Med Microbiol	10.1016/j.ijmm.2008.10.005	2009	*
Pathogenicity	Insights into the mode of action of chitosan as an antibacterial compound.	Raafat D, von Bargen K, Haas A, Sahl HG	Appl Environ Microbiol	10.1128/AEM.00453-08	2008	*
Pathogenicity	Mode of action of human beta-defensin 3 against Staphylococcus aureus and transcriptional analysis of responses to defensin challenge.	Sass V, Pag U, Tossi A, Bierbaum G, Sahl HG	Int J Med Microbiol	10.1016/j.ijmm.2008.01.011	2008	*
Pathogenicity	Analysis of in vitro activities and modes of action of synthetic antimicrobial peptides derived from an alpha-helical 'sequence template'.	Pag U, Oedenkoven M, Sass V, Shai Y, Shamova O, Antcheva N, Tossi A, Sahl HG	J Antimicrob Chemother	10.1093/jac/dkm479	2008	*
Pathogenicity	Volsurf analysis of carbapenem antibiotics.	Doddareddy MR, Cha JH, Cho YS, Koh HY, Yoo KH, Kim DJ, Pae AN	Bioorg Med Chem	10.1016/j.bmc.2005.03.018	2005	*
Metabolism	Staphylococcus aureus penicillin-binding protein 4 and intrinsic beta-lactam resistance.	Henze UU, Berger-Bachi B	Antimicrob Agents Chemother	10.1128/AAC.39.11.2415	1995	*
Enzymology	Antibacterial phenylpropanoid glycosides from Paulownia tomentosa Steud.	Kang KH, Jang SK, Kim BK, Park MK	Arch Pharm Res	10.1007/BF02979128	1994	*
Metabolism	RU 29 246, the active compound of the cephalosporin-prodrug-ester HR 916. II. Stability to beta-lactamases and affinity for penicillin-binding proteins.	Markus A, Klesel N, Wollmann T, Isert D, Limbert M, Schrinner E, Seibert G, Bauernfeind A, Jungwirth R, Wilhelm R, et al.	J Antibiot (Tokyo)	10.7164/antibiotics.45.521	1992	*
Metabolism	A novel labeling procedure of anteiso-fatty acid-containing lipids in staphylococci for investigating the effect of penicillin on lipid release.	Rozgonyi F, Hahn H, Labischinski H, Giesbrecht P	FEMS Microbiol Lett	10.1016/0378-1097(90)90024-k	1990	*
Pathogenicity	[Microbiologic studies of the lung clearance of rats after aerogenous long term exposure to ammonia].	Kastner P, Mehlhorn G	Arch Exp Veterinarmed		1989	*
Pathogenicity	[Escape of hydrogen peroxide and oxygen from the root canal].	Glockmann E, Oehring H, Hoffmann B, Lange G, Weisser G, Wunderlich I	Zahn Mund Kieferheilkd Zentralbl		1989	*
Pathogenicity	Synthesis and structure-activity relationships in the cefpirome series. I. 7-[2-(2-Aminothiazol-4-yl)-2-(Z)-oxyiminoacetamido]-3-[(su bstituted-1-pyridinio)methyl]ceph-3-em-4-carboxylate s.	Lattrell R, Blumbach J, Duerckheimer W, Fehlhaber HW, Fleischmann K, Kirrstetter R, Mencke B, Scheunemann KH, Schrinner E, Schwab W, et al.	J Antibiot (Tokyo)	10.7164/antibiotics.41.1374	1988	*
Enzymology	Bovine leukocyte phagocytosis and bacteria killing monitored by intracellular acridine orange fluorescence and extracellular fluorescence quenching.	Zanetti M, Schmitt M, Lazary S	Vet Immunol Immunopathol	10.1016/0165-2427(87)90017-1	1987	*
Pathogenicity	[Effect of colchicine and indomethacin on leukocytic phagocytosis of Staphylococcus aureus and E. coli].	Schleef H, Stelzner A, Kunze M	Zentralbl Bakteriol Mikrobiol Hyg A		1984	*
Pathogenicity	[Studies on the mycotic and bacterial risk of contamination and the use of nipagin in the artificial insemination of cryosperm].	Glander HG, Rytter M, Schonborn C	Zentralbl Gynakol		1984	*
Pathogenicity	[Effect of carrageenan, galactose and 2,4-dinitrophenol on leukocyte phagocytosis of Staphylococcus aureus and E. coli].	Stelzner A, Schleef H, Kunze M	Allerg Immunol (Leipz)		1984	*
Enzymology	Microbiological investigations on cryopreserved human semen.	Glander HJ, Schonborn C, Rytter M	Int J Androl	10.1111/j.1365-2605.1983.tb00550.x	1983	*
Pathogenicity	Measurements of nonspecific humoral immune parameters in patients with chronic pyelonephritis.	Stein G, Stelzner A	Clin Nephrol		1981	*
Pathogenicity	[The clinical value of unspecific humoral immune parameters. Attempt at an immunogram. II. Quantitative determination of CH50E, CB50E, C3, C4 and lysozyme and measurement of indirect phagocytosis rate in the serum of patients with chronic pyelonephritis].	Stelzner A, Stein G, Kittlick M	Z Gesamte Inn Med		1979	*
Pathogenicity	Antimicrobial activity of tibezonium (TBZ).	Veronese M, Salvaterra M, Setnikar I	Chemotherapy	10.1159/000221976	1977	*
Metabolism	Cervimycin-Resistant Staphylococcus aureus Strains Display Vancomycin-Intermediate Resistant Phenotypes.	Dietrich A, Steffens U, Gajdiss M, Boschert AL, Droge JK, Szekat C, Sass P, Malik IT, Bornikoel J, Reinke L, Macek B, Franz-Wachtel M, Nieselt K, Harbig T, Scherlach K, Brotz-Oesterhelt H, Hertweck C, Sahl HG, Bierbaum G	Microbiol Spectr	10.1128/spectrum.02567-22	2022	*
	The hypersusceptible antibiotic screening strain Staphylococcus aureus SG511-Berlin harbors multiple mutations in regulatory genes.	Dietrich A, Steffens U, Sass P, Bierbaum G	Int J Med Microbiol	10.1016/j.ijmm.2021.151545	2021	*
	[The disposition and clearance of inhaled bacteria (Staphylococcus aureus) in the lungs of piglets].	Kastner P, Mehlhorn G	Arch Exp Veterinarmed		1989	*

References

#2554

Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 6247

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#59547 Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 52423

#68375

Automatically annotated from API ID32STA .

#83597

Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.: StrainInfo: A central database for resolving microbial strain identifiers . ( DOI 10.60712/SI-ID48129.1 )

* These data were automatically processed and therefore are not curated

Change proposal

You found an error in BacDive? Please tell us about it!

Note that changes will be reviewed and judged. If your changes are legitimate, changes will occur within the next BacDive update. Only proposed changes supported by the according reference will be reviewed. The BacDive team reserves the right to reject proposed changes.

Search for species Staphylococcus aureus in external resources:
SILVA
BRENDA
PANGAEA
GBIF