Staphylococcus aureus (DSM 46320, IMET 11039, 1309)
Staphylococcus aureus 1309 is a human pathogen that has multiple antibiotic resistances.
antibiotic resistance human pathogen BacteriaName and taxonomic classification
SI-ID 50809
DSM 46320,IMET 11039
| @ref 20215 |
Last LPSN update
2026-05-29 08:28:18 |
| Domain Bacteria |
| Phylum Bacillota |
| Class Bacilli |
| Order Caryophanales |
| Family Staphylococcaceae |
| Genus Staphylococcus |
| Species Staphylococcus aureus |
| Full scientific name Staphylococcus aureus Rosenbach 1884 (Approved Lists 1980) |
| Synonyms (2) |
Culture and growth conditions
Culture medium
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 12521 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | Medium recipe at MediaDive  | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base | ||
| 12521 | TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) | Medium recipe at MediaDive | Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water |
Culture temp
| @ref | Growth | Type | Temperature (°C) | |
|---|---|---|---|---|
| 12521 | positive | growth | 37 |
Physiology and metabolism
Antibiotic susceptibility testing
| Test 1 | Test 2 | Test 3 | Test 4 | Test 5 | Test 6 | |
|---|---|---|---|---|---|---|
| @ref | 12521 | 12521 | 12521 | 12521 | 12521 | 12521 |
| Medium | Mueller-Hinton Agar | Mueller-Hinton Agar | Mueller-Hinton Agar | Mueller-Hinton Agar | Mueller-Hinton Agar | Müller-Hinton Agar |
| Manual annotation | 1 | 1 | 1 | 1 | 1 | 1 |
| Inhibition zone diameter in mm | Inhibition zone diameter in mm | Inhibition zone diameter in mm | Inhibition zone diameter in mm | Inhibition zone diameter in mm | Inhibition zone diameter in mm | |
| Amikacin 30µg (disc) | 24 | 12-14 | 26 | 26 | 26 | 26 |
| Ampicillin 10µg (disc) | 10 | 6 | 10 | 8 | 8 | 8 |
| Aztreonam 30µg (disc) | 0 | 0 | 0 | 0 | 0 | 0 |
| Bacitracin 10Unit | 26-28 | 18 | 28 | 26 | 26 | n.d. |
| Cefalotin 30µg (disc) | 10 | 0 | 8-10 | 8 | 8 | n.d. |
| Cefazolin 30µg (disc) | 0 | 0 | 0 | 0 | 0 | n.d. |
| Cefiderocol 30µg (disc) | n.d. | n.d. | n.d. | n.d. | n.d. | 0 |
| Cefotaxime 30µg (disc) | 0 | 0 | 0 | 0 | 0 | 0 |
| Ceftazidime 10µg (disc) | n.d. | n.d. | n.d. | n.d. | n.d. | 0 |
| Ceftriaxone 30µg (disc) | 0 | n.d. | n.d. | 0 | 0 | 0 |
| Chloramphenicol 30µg (disc) | 28 | 14 | 30 | 30 | 30 | 32 |
| Ciprofloxacin 5µg (disc) | n.d. | n.d. | n.d. | n.d. | n.d. | 26-28 |
| Clindamycin 10µg (disc) | 34 | n.d. | n.d. | 36-38 | 36-38 | 40 |
| Colistin 10µg (disc) | 0 | 0 | 0 | 0 | 0 | n.d. |
| Colistin sulphate 10µg (disc) | n.d. | n.d. | n.d. | n.d. | n.d. | 0 |
| Doxycycline 30µg (disc) | 10 | 8 | 12 | 10 | 10 | n.d. |
| Erythromycin 15µg (disc) | 10 | 6-8 | 12 | 10 | 10 | 12 |
| Fosfomycin 50µg (disc) | 32-34 | n.d. | n.d. | 32 | 32 | 32 |
| Gentamicin 10µg (disc) | 24 | 16 | 26 | 26 | 26 | n.d. |
| Gentamicin 30µg (disc) | n.d. | n.d. | n.d. | n.d. | n.d. | 26 |
| Imipenem 10µg (disc) | 12 | 0 | 10 | 10 | 10 | 6 |
| Kanamycin 30µg (disc) | 36 | 14-16 | 26 | 28 | 28 | 26 |
| Levofloxacin 5µg (disc) | n.d. | n.d. | n.d. | n.d. | n.d. | 30 |
| Lincomycin 15µg (disc) | 26-28 | 20-22 | 30 | 28 | 28 | n.d. |
| Linezolid 10µg (disc) | 26-28 | n.d. | n.d. | 36 | 36 | 38 |
| Meropenem 10µg (disc) | n.d. | n.d. | n.d. | n.d. | n.d. | 8 |
| Mezlocillin 30µg (disc) | 10 | 0 | 10 | 8 | 8 | n.d. |
| Moxifloxacin 5µg (disc) | 30 | n.d. | n.d. | 30 | 30 | 32 |
| Neomycin 30µg (disc) | 22 | 18 | 24 | 24-26 | 24-26 | n.d. |
| Nitrofurantoin 100µg (disc) | 22 | 14-16 | 22 | 20-22 | 20-22 | 24-26 |
| Norfloxacin 10µg (disc) | 22 | 18-20 | 24-26 | 22 | 22 | n.d. |
| Nystatin 100Unit | 0 | n.d. | n.d. | 0 | 0 | n.d. |
| Ofloxacin 5µg (disc) | 26 | 16 | 26 | 26 | 26 | 28 |
| Oxacillin 5µg (disc) | 0 | 0 | 0 | 0 | 0 | 0 |
| Penicillin G 6µg (disc) | 8 | 0 | 6 | 6 | 6 | 6 |
| Pipemidic acid 20µg (disc) | 10 | 0 | 6 | 8 | 8 | n.d. |
| Piperacillin/Tazobactam 40µg (disc) | 10-12 | n.d. | n.d. | 10 | 10 | n.d. |
| Piperacillin/Tazobactam 110µg (disc) | n.d. | n.d. | n.d. | n.d. | n.d. | 6 |
| Polymyxin B 300Unit | 8 | 0 | 6-8 | 6 | 6 | 6 |
| Quinupristin/Dalfopristin 15µg (disc) | 26-28 | n.d. | n.d. | 28 | 28 | 30-32 |
| Rifampicin 5µg (disc) | n.d. | n.d. | n.d. | n.d. | n.d. | 38 |
| Teicoplanin 30µg (disc) | 16-18 | n.d. | n.d. | 18 | 18 | 16 |
| Tetracycline 30µg (disc) | 0 | 0 | 6 | 6 | 6 | 6 |
| Ticarcillin 75µg (disc) | 10 | 8 | 10 | 10 | 10 | 8 |
| Tigecycline 15µg (disc) | n.d. | n.d. | n.d. | n.d. | n.d. | 22 |
| Trimethoprim-sulfamethoxazole (1:19) 10µg (disc) | n.d. | n.d. | n.d. | n.d. | n.d. | 12 |
| Vancomycin 30µg (disc) | 20 | 12 | 20 | 20 | 20 | 20 |
Observation
| 12521 | ObservationMRSA |
Metabolite utilization
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68375 | 22599 ChEBI | arabinose | - | fermentation | from API ID32STA |
| 68375 | 29016 ChEBI | arginine | + | hydrolysis | from API ID32STA |
| 68375 | 17057 ChEBI | cellobiose | - | fermentation | from API ID32STA |
| 68375 | 15824 ChEBI | D-fructose | + | fermentation | from API ID32STA |
| 68375 | 17634 ChEBI | D-glucose | + | fermentation | from API ID32STA |
| 68375 | 16899 ChEBI | D-mannitol | + | fermentation | from API ID32STA |
| 68375 | 16024 ChEBI | D-mannose | + | fermentation | from API ID32STA |
| 68375 | 16988 ChEBI | D-ribose | - | fermentation | from API ID32STA |
| 68375 | 4853 ChEBI | esculin | - | hydrolysis | from API ID32STA |
| 68375 | 17716 ChEBI | lactose | + | fermentation | from API ID32STA |
| 68375 | 17306 ChEBI | maltose | + | fermentation | from API ID32STA |
| 68375 | 59640 ChEBI | N-acetylglucosamine | + | fermentation | from API ID32STA |
| 68375 | 17632 ChEBI | nitrate | + | reduction | from API ID32STA |
| 68375 | 18257 ChEBI | ornithine | - | degradation | from API ID32STA |
| 68375 | 16634 ChEBI | raffinose | - | fermentation | from API ID32STA |
| 68375 | 17992 ChEBI | sucrose | + | fermentation | from API ID32STA |
| 68375 | 27082 ChEBI | trehalose | + | fermentation | from API ID32STA |
| 68375 | 32528 ChEBI | turanose | + | fermentation | from API ID32STA |
| 68375 | 16199 ChEBI | urea | + | hydrolysis | from API ID32STA |
Antibiotic resistance
| @ref | ChEBI | Metabolite | Is resistant | Resistance conc. | |
|---|---|---|---|---|---|
| 12521 | 161680 | Aztreonam | 30 µg (disc) | from Antibiotic test | |
| 12521 | 474053 | Cefazolin | 30 µg (disc) | from Antibiotic test | |
| 12521 | 140376 | Cefiderocol | 30 µg (disc) | from Antibiotic test | |
| 12521 | 204928 | Cefotaxime | 30 µg (disc) | from Antibiotic test | |
| 12521 | 3508 | Ceftazidime | 10 µg (disc) | from Antibiotic test | |
| 12521 | 29007 | Ceftriaxone | 30 µg (disc) | from Antibiotic test | |
| 12521 | 37943 | Colistin | 10 µg (disc) | from Antibiotic test | |
| 12521 | 37943 | Colistin sulphate | 10 µg (disc) | from Antibiotic test | |
| 12521 | 7660 | Nystatin | 100 Unit | from Antibiotic test | |
| 12521 | 7809 | Oxacillin | 5 µg (disc) | from Antibiotic test |
Metabolite production
| @ref | Chebi-ID | Metabolite | Production | |
|---|---|---|---|---|
| 68375 | 15688 ChEBI | acetoin | from API ID32STA |
Metabolite tests
| @ref | Chebi-ID | Metabolite | Voges-proskauer-test | |
|---|---|---|---|---|
| 68375 | 15688 ChEBI | acetoin | + | from API ID32STA |
Enzymes
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68375 | alkaline phosphatase | + | 3.1.3.1 | from API ID32STA |
| 68375 | arginine dihydrolase | + | 3.5.3.6 | from API ID32STA |
| 68375 | beta-galactosidase | - | 3.2.1.23 | from API ID32STA |
| 68375 | beta-glucosidase | - | 3.2.1.21 | from API ID32STA |
| 68375 | beta-glucuronidase | - | 3.2.1.31 | from API ID32STA |
| 68375 | L-arginine arylamidase | - | from API ID32STA | |
| 68375 | ornithine decarboxylase | - | 4.1.1.17 | from API ID32STA |
| 68375 | urease | + | 3.5.1.5 | from API ID32STA |
API ID32STA
| @ref | URE | ADH (Arg) | ODC | ESC | GLU | FRU | MNE | MAL | LAC | TRE | MAN | RAF | RIB | CEL | Reduction of nitrateNIT | Acetoin production (Voges Proskauer test)VP | beta GAL | L-arginine arylamidaseArgA | PAL | Pyrrolidonyl arylamidasePyrA | NOVO | SAC | NAG | TUR | ARA | beta GUR | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 12521 | + | + | - | - | + | + | + | + | + | + | + | - | - | - | + | + | - | - | + | + | - | + | + | + | - | - | |
| 12521 | + | + | - | - | + | + | + | + | + | + | + | - | - | - | + | + | - | - | + | - | +/- | + | + | + | - | - | |
| 12521 | + | + | - | - | + | + | + | + | + | + | + | - | - | - | + | + | - | - | + | - | - | + | + | + | - | - | |
| 12521 | + | + | - | - | + | + | + | + | + | + | + | - | - | - | + | + | - | - | + | - | + | + | + | + | - | - |
Literature
Literature 
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Initial adhesion of methicillin-sensitive and methicillin-resistant Staphylococcus aureus strains to untreated and electropolished surgical steel drill bits. | Langsteiner A, Loncaric I, Henkel-Odwody AM, Tichy A, Licka TF. | Res Vet Sci | 10.1016/j.rvsc.2017.09.016 | 2017 | | |
| Establishment of a Real-Time PCR Assay for the Detection of Devriesea agamarum in Lizards. | Brockmann M, Leineweber C, Hellebuyck T, Martel A, Pasmans F, Gentil M, Muller E, Marschang RE. | Animals (Basel) | 10.3390/ani13050881 | 2023 | | |
| Lyophilized allogeneic bone tissue as an antibiotic carrier. | Coraca-Huber DC, Ammann CG, Nogler M, Fille M, Frommelt L, Kuhn KD, Folsch C. | Cell Tissue Bank | 10.1007/s10561-016-9582-5 | 2016 | | |
| Pathogenicity | In vitro activity of fosfomycin in combination with various antistaphylococcal substances. | Grif K, Dierich MP, Pfaller K, Miglioli PA, Allerberger F. | J Antimicrob Chemother | 10.1093/jac/48.2.209 | 2001 | |
| Enzymology | Methicillin-resistant Staphylococcus aureus screening by online immunometric monitoring of bacterial growth under selective pressure. | Stenholm T, Hakanen AJ, Vaarno J, Pihlasalo S, Terho P, Hanninen PE, Vuopio-Varkila J, Huovinen P, Kotilainen P. | Antimicrob Agents Chemother | 10.1128/aac.00518-09 | 2009 | |
How to cite
If you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive14492.20260601.11
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain dataIsabel Schober, Julia Koblitz, Joaquim Sardà Carbasse, Christian Ebeling, Marvin Leon Schmidt, Adam Podstawka, Rohit Gupta, Vinodh Ilangovan, Javad Chamanara, Jörg Overmann, Lorenz Christian Reimer
Nucleic Acids Research; database issue 2025.
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