Name: Staphylococcus aureus MRSA
Creator: BacDive
License: https://creativecommons.org/licenses/by/4.0/

Strain identifier

BacDive ID: 14460

Type strain:

Species: Staphylococcus aureus

Strain Designation: MRSA, 1063, MRSA BBL

Culture col. no.: DSM 11729, ATCC 33592

Strain history: <- Becton Dickinson <- ATCC <- S. Schaefler, 1063 <- Bellevue Hosp., New York City

NCBI tax ID(s): 1280 (species)

SI-ID 9372

LMG 15154, ATCC 33592, DSM 11729, BCRC 14976, CCRC 14976

Special Collections

DSMZ

Other strains from Staphylococcus aureus

Section

Staphylococcus aureus MRSA is a human pathogen that has multiple antibiotic resistances and was isolated from blood.

antibiotic resistance
human pathogen
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	14-12-2023 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Bacillota*
	Class	*Bacilli*
	Order	*Caryophanales*
	Family	*Staphylococcaceae*
	Genus	*Staphylococcus*
	Species	**Staphylococcus aureus**
	Full Scientific Name (LPSN)	Staphylococcus aureus Rosenbach 1884 (Approved Lists 1980)

Synonym

Staphylococcus aureus subsp. anaerobius

Information on morphological and physiological properties Morphology

[Ref.: #4460]	Type of hemolysis	beta
[Ref.: #4460]	Hemolysis ability	1
[Ref.: #4460]	Incubation period	1-2 days

Information on culture and growth conditions Culture and growth conditions

[Ref.: #4460]

Culture medium

COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)

[Ref.: #4460]

Culture medium growth

[Ref.: #4460]

Culture medium link

Medium recipe at MediaDive

[Ref.: #4460]

Culture medium composition

expand / minimize

[Ref.: #4460]

Culture medium

TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)

[Ref.: #4460]

Culture medium growth

[Ref.: #4460]

Culture medium link

Medium recipe at MediaDive

[Ref.: #4460]

Culture medium composition

expand / minimize

	Temperatures	Kind of temperature		Temperature
[Ref.: #4460]			growth	37 °C

Information on physiology and metabolism Physiology and metabolism

Note that the displayed test results represent raw data and therefore may deviate!

Antibiotic susceptibility testing

Test 1

Test 2

Test 3

Test 4

Test 5

Test 6

Test 7

Test 8

Test 9

Test 10

Test 11

Reference

[Ref.: #4460]
Mueller-Hinton Agar
37
1
aerob
yes
Inhibition zone diameter in mm
20
28
20
24
20
32
28-30
30-32
resistant0
48-50
12
8
24
22
20
6-8
30
30
26-28
resistant0
12
26
28
10
resistant0
12
20
30
38
30-32
34
36
resistant0
28-30
18
26

[Ref.: #4460]
Mueller-Hinton Agar
37

aerob
yes
Inhibition zone diameter in mm
8-10
resistant0
10
10-12
10
10-12
10
10
resistant0
14-16
resistant0
8
24-26
20-22
20
10-12
32
30
28-30
resistant0
10-12
28
26
8
resistant0
12
10
8
40
30-32
34-36
32-34
resistant0
30
18
12-14

[Ref.: #4460]
Mueller-Hinton Agar
37


yes
Inhibition zone diameter in mm
6-8
resistant0
8-10
10
10
10
resistant0
resistant0
resistant0
10
resistant0
10
28
24
22
12
32
32
30-32
resistant0
12
30
28
6-8
resistant0
10-12
14
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.

[Ref.: #4460]
Mueller-Hinton Agar
37


yes
Inhibition zone diameter in mm
resistant0
resistant0
resistant0
8
resistant0
6
8
resistant0
resistant0
6
resistant0
8
12
12
10
6
16
18
20
resistant0
10
14
18
6
resistant0
10
8
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.

[Ref.: #4460]
Mueller-Hinton Agar
37


yes
Inhibition zone diameter in mm
resistant0
resistant0
8
6
resistant0
8
resistant0
resistant0
resistant0
resistant0
resistant0
8
14
12
12
6
14
14
16
resistant0
8
16
18
resistant0
resistant0
6
8
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.

[Ref.: #4460]
Mueller-Hinton Agar
37


yes
Inhibition zone diameter in mm
resistant0
resistant0
resistant0
6
resistant0
6
resistant0
resistant0
resistant0
6
resistant0
8
14
12
12
6
16
16
16
resistant0
8
16
20
resistant0
resistant0
6
8
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.

[Ref.: #4460]
Mueller-Hinton Agar



yes
Inhibition zone diameter in mm
6
resistant0
10
12
8-10
8-10
resistant0
resistant0
resistant0
12
resistant0
8
24
22
20
10
30-32
30
30-32
resistant0
12-14
28
26-28
8
12
10
10-12
resistant0
36
32
34
28-30
resistant0
28
18
12

[Ref.: #4460]
Mueller-Hinton Agar
37
1

yes
Inhibition zone diameter in mm
10
8
10
12-14
10
14
10-12
10
resistant0
22
6
8
26
24
18-20
10
34
30
30
resistant0
14
28
28
10
resistant0
12
10
8-10
40
30-32
36
34
resistant0
28
18
12-14

[Ref.: #4460]
Mueller-Hinton Agar



yes
Inhibition zone diameter in mm
10
8
10-12
14
10
12-14
10-12
resistant0
resistant0
16
resistant0
8
24
22
20
10
32
30-32
30
resistant0
12
28
28
8
resistant0
14
10
8
38-40
28-30
34-36
30
resistant0
28
16-18
12

[Ref.: #4460]
Mueller-Hinton Agar
37

aerob
yes
Inhibition zone diameter in mm
20
28
20
24-26
20
34
32
28-30
resistant0
48
12-14
8
26
22-24
20
10
30
30-32
30
resistant0
16
30
26
6
resistant0
12-14
20
32-34
38-40
30-32
36
34-36
resistant0
28
18
26

[Ref.: #4460]
Mueller-Hinton Agar
37

aerob
yes
Inhibition zone diameter in mm
8-10
resistant0
10
10-12
10
10-12
10
10
resistant0
14-16
resistant0
8
24-26
20-22
20
10-12
32
30
28-30
resistant0
10-12
28
26
8
resistant0
12
10
8
40
30-32
34-36
32-34
resistant0
30
18
12-14

Only first 15 entries are displayed. Click here to see all.

[Ref.: #4460]

Observation

not MRSA

	Metabolite	Utilization activity	Kind of utilization tested
[Ref.: #68375]	arabinose ChEBI	-	fermentation	* from API ID32STA
[Ref.: #68375]	arginine ChEBI	+	hydrolysis	* from API ID32STA
[Ref.: #68375]	cellobiose ChEBI	-	fermentation	* from API ID32STA
[Ref.: #68375]	D-fructose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	D-glucose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	D-mannitol ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	D-mannose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	D-ribose ChEBI	-	fermentation	* from API ID32STA
[Ref.: #68375]	esculin ChEBI	-	hydrolysis	* from API ID32STA
[Ref.: #68375]	lactose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	maltose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	N-acetylglucosamine ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	nitrate ChEBI	+	reduction	* from API ID32STA
[Ref.: #68375]	ornithine ChEBI	-	degradation	* from API ID32STA
[Ref.: #68375]	sucrose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	trehalose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	turanose ChEBI	+	fermentation	* from API ID32STA
	Only first 10 entries are displayed. Click here to see all.

	Metabolite production	Metabolite	Production
[Ref.: #68375]		acetoin ChEBI	yes	* from API ID32STA

	Physiological tests	Metabolite	Voges-Proskauer-test
[Ref.: #68375]		acetoin ChEBI	+	* from API ID32STA

	Enzyme	Enzyme activity	EC number
[Ref.: #68375]	alkaline phosphatase	+	3.1.3.1	* from API ID32STA
[Ref.: #68375]	arginine dihydrolase	+	3.5.3.6	* from API ID32STA
[Ref.: #68375]	beta-galactosidase	-	3.2.1.23	* from API ID32STA
[Ref.: #68375]	beta-glucosidase	-	3.2.1.21	* from API ID32STA
[Ref.: #68375]	beta-glucuronidase	-	3.2.1.31	* from API ID32STA
[Ref.: #4460]	catalase	+	1.11.1.6
[Ref.: #4460]	cytochrome-c oxidase	-	1.9.3.1
[Ref.: #68375]	ornithine decarboxylase	-	4.1.1.17	* from API ID32STA

API® ID32STA:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Urease/urea hydrolysisURE	Arginine dihydrolaseADH (Arg)	Ornithine decarboxylaseODC	Esculin hydrolysisESC	Fermentation of D-glucoseGLU	Fermentation of D-fructoseFRU	Fermentation of D-mannoseMNE	Fermentation of maltoseMAL	Fermentation of lactoseLAC	Fermentation of trehaloseTRE	Fermentation of D-mannitolMAN	Fermentation of raffinoseRAF	Fermentation of D-riboseRIB	Fermentation of cellobioseCEL	Reduction of nitrateNIT	Acetoin production (Voges Proskauer test)VP	beta-Galactosidasebeta GAL	L-arginine arylamidaseArgA	Alkaline phosphatasePAL	Pyrrolidonyl arylamidasePyrA	Novobiocin resistanceNOVO	Fermentation of sucroseSAC	Fermentation of N-acetyl-glucosamineNAG	Fermentation of turanoseTUR	Fermentation of arabinoseARA	beta-Glucuronidasebeta GUR
[Ref.: #4460]	6299	+	+	-	-	+	+	+	+	+	+	+	+	-	-	+	+	-	+	+	-	+	+	+	+	-	-
[Ref.: #4460]	6259	-	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	-	+/-	+	+	+	-	-
[Ref.: #4460]	5854	+	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	-	+	+	+	+	-	-
[Ref.: #4460]	5853	+	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	-	-	+	+	+	-	-
[Ref.: #4460]	5852	+	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	+/-	+/-	+	+	+	-	-
[Ref.: #4460]	5851	+	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	-	-	+	+	+	-	-
[Ref.: #4460]	5850	+	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	-	+	+	+	+	-	-
[Ref.: #4460]	5849	-	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	-	+/-	+	+	+	-	-
[Ref.: #4460]	5755	-	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	-	-	+	+	+	-	-

Information on isolation source, the sampling and environmental conditions Isolation, sampling and environmental information

[Ref.: #4460]	Sample type/isolated from	blood
[Ref.: #4460]	Country	USA
[Ref.: #4460]	Country ISO 3 Code	USA
[Ref.: #4460]	Continent	North America
* marker position based on {}

Isolation sources categories

#Host Body Product	#Fluids	#Blood
#Infection	#Patient	-

What are isolation sources categories?

Information on possible application of the strain and its possible interaction with e.g. potential hosts Safety information

[Ref.: #4460]	Pathogenicity (human)	yes
[Ref.: #4460]	Pathogenicity (animal)	yes
[Ref.: #4460]	Biosafety level	2	Risk group (German classification) According to TRBA 466

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

Genome sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence accession description	Seq. accession number	Assembly level	Sequence database	Associated NCBI tax ID
[Ref.: #66792]	Staphylococcus aureus MRSA	GCA_001291325	scaffold	GenBank ENA	1280 tax ID	*
[Ref.: #66792]	Staphylococcus aureus MRSA	GCA_900082285	scaffold	GenBank ENA	1280 tax ID	*
[Ref.: #66792]	Staphylococcus aureus MRSA	GCA_900082345	scaffold	GenBank ENA	1280 tax ID	*
[Ref.: #66792]	Staphylococcus aureus MRSA	GCA_900083125	scaffold	GenBank ENA	1280 tax ID	*
[Ref.: #66792]	Staphylococcus aureus MRSA	GCA_900082185	scaffold	GenBank ENA	1280 tax ID	*
[Ref.: #66792]	Staphylococcus aureus MRSA	GCA_900081935	scaffold	GenBank ENA	1280 tax ID	*

Data predicted using genome information as a basis Genome-based predictions

	Trait	Model	Prediction	Confidence in %	In training data
	Predictions from GenomeNet Sporulation v. 1 based on: Staphylococcus aureus strain 1063 PATRIC: 1280.4837
[Ref.: #69481]	spore-forming	spore-formingⓘ	no	82	no

	Trait	Model	Prediction	Confidence in %	In training data
	Predictions from Diaspora project based on: Staphylococcus aureus MRSA NCBI: GCA_900082905.1
[Ref.: #69480]	gram-positive	gram-positiveⓘ	yes	84.927	no
[Ref.: #69480]	anaerobic	anaerobicⓘ	no	98.914	no
[Ref.: #69480]	aerobic	aerobicⓘ	yes	51.905	no
[Ref.: #69480]	spore-forming	spore-formingⓘ	no	72.192	no
[Ref.: #69480]	thermophilic	thermophileⓘ	no	94.74	no
[Ref.: #69480]	flagellated	motile2+ⓘ	no	81.387	no

Availability in culture collections External links

[Ref.: #4460]

Culture collection no.

DSM 11729, ATCC 33592

[Ref.: #83600]

SI-ID 9372

Literature:

Only first 10 entries are displayed. Click here to see all.

	Title	Authors	Journal	DOI	Year
Pathogenicity	Sustainable Low-Volume Analysis of Environmental Samples by Semi-Automated Prioritization of Extracts for Natural Product Research (SeaPEPR).	Riyanti, Marner M, Hartwig C, Patras MA, Wodi SIM, Rieuwpassa FJ, Ijong FG, Balansa W, Schaberle TF	Mar Drugs	10.3390/md18120649	2020	*
Pathogenicity	Defense involvement of piscidin from striped murrel Channa striatus and its peptides CsRG12 and CsLC11 involvement in an antimicrobial and antibiofilm activity.	Stefi Raju V, Sarkar P, Pachaiappan R, Paray BA, Al-Sadoon MK, Arockiaraj J	Fish Shellfish Immunol	10.1016/j.fsi.2020.02.027	2020	*
Pathogenicity	Silver Nanoparticles Synthesized by Using the Endophytic Bacterium Pantoea ananatis are Promising Antimicrobial Agents against Multidrug Resistant Bacteria.	Monowar T, Rahman MS, Bhore SJ, Raju G, Sathasivam KV	Molecules	10.3390/molecules23123220	2018	*
Pathogenicity	In vitro antimicrobial activity of plants used in traditional medicine in Gurage and Silti Zones, south central Ethiopia.	Teka A, Rondevaldova J, Asfaw Z, Demissew S, Van Damme P, Kokoska L, Vanhove W	BMC Complement Altern Med	10.1186/s12906-015-0822-1	2015	*
Pathogenicity	Anti-methicillin-resistant Staphylococcus aureus assay of azalomycin F5a and its derivatives.	Yuan GJ, Li PB, Yang J, Pang HZ, Pei Y	Chin J Nat Med	10.1016/S1875-5364(14)60061-3	2014	*
Pathogenicity	Inspiration from old dyes: tris(stilbene) compounds as potent gram-positive antibacterial agents.	Boulos RA, Man NY, Lengkeek NA, Hammer KA, Foster NF, Stemberger NA, Skelton BW, Wong PY, Martinac B, Riley TV, McKinley AJ, Stewart SG	Chemistry	10.1002/chem.201303119	2013	*
Pathogenicity	Reducing the risk of infection in vascular access patients: an in vitro evaluation of an antimicrobial silver nanotechnology luer activated device.	Edmiston CE Jr, Markina V	Am J Infect Control	10.1016/j.ajic.2009.09.010	2010	*
Pathogenicity	Syntheses of carnosic acid and carnosol, anti-oxidants in Rosemary, from pisiferic acid, the major constituent of Sawara.	Tada M, Ohkanda T, Kurabe J	Chem Pharm Bull (Tokyo)	10.1248/cpb.58.27	2010	*
Pathogenicity	Antibacterial activity of anacardic acid and totarol, alone and in combination with methicillin, against methicillin-resistant Staphylococcus aureus.	Muroi H, Kubo I	J Appl Bacteriol	10.1111/j.1365-2672.1996.tb03233.x	1996	*
Phylogeny	Isolation, Molecular Identification and Antibacterial Potential of Marine Bacteria from Deep Atlantic Ocean of Morocco.	Chbel A, Rodriguez-Castro J, Quinteiro J, Rey-Mendez M, Delgado AS, Soukri A, Khalfi BE	Avicenna J Med Biotechnol	10.18502/ajmb.v14i3.9827	2022	*
	Plate-associated localized osteitis in mini-pig by biofilm-forming Methicillin-resistant Staphylococcus aureus (MRSA): establishment of a novel experimental model.	Jaekel C, Windolf CD, Sager M, Wollschlager LM, Hoffmanns M, Grassmann JP	Eur J Trauma Emerg Surg	10.1007/s00068-022-01894-2	2022	*
	Antibacterial Activity of Silver Nanoparticles (AgNP) Confined to Mesostructured, Silica-Based Calcium Phosphate Against Methicillin-Resistant Staphylococcus Aureus (MRSA).	Kung JC, Wang WH, Lee CL, Hsieh HC, Shih CJ	Nanomaterials (Basel)	10.3390/nano10071264	2020	*

References

#4460

Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 11729

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#66792

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#68375

Automatically annotated from API ID32STA .

#69480

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#69481

Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch: Predictions based on the model GenomeNet Sporulation v. 1 . ( DOI 10.21203/rs.3.rs-2527258/v1 )

#83600

Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.: StrainInfo: A central database for resolving microbial strain identifiers . ( DOI 10.60712/SI-ID9372.1 )

* These data were automatically processed and therefore are not curated

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Staphylococcus aureus strain 1063

Staphylococcus aureus MRSA

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Change proposal