Pseudomonas aeruginosa PA-103 is an aerobe, mesophilic, Gram-negative prokaryote of the family Pseudomonadaceae.
Gram-negative motile rod-shaped aerobe mesophilic| @ref 20215 |
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| Domain Pseudomonadati |
| Phylum Pseudomonadota |
| Class Gammaproteobacteria |
| Order Pseudomonadales |
| Family Pseudomonadaceae |
| Genus Pseudomonas |
| Species Pseudomonas aeruginosa |
| Full scientific name Pseudomonas aeruginosa (Schroeter 1872) Migula 1900 (Approved Lists 1980) |
| Synonyms (2) |
| @ref | Gram stain | Cell shape | Motility | |
|---|---|---|---|---|
| 38746 | negative | rod-shaped |
| @ref | Name | Growth | Composition | Medium link | |
|---|---|---|---|---|---|
| 38746 | MEDIUM 72- for trypto casein soja agar | Distilled water make up to (1000.000 ml);Trypto casein soy agar (40.000 g) | |||
| 38746 | CIP Medium 72 | Medium recipe at CIP |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68369 | 17128 ChEBI | adipate | + | assimilation | from API 20NE |
| 68369 | 29016 ChEBI | arginine | + | hydrolysis | from API 20NE |
| 68369 | 17634 ChEBI | D-glucose | + | assimilation | from API 20NE |
| 68369 | 17634 ChEBI | D-glucose | - | fermentation | from API 20NE |
| 68369 | 16899 ChEBI | D-mannitol | + | assimilation | from API 20NE |
| 68369 | 16024 ChEBI | D-mannose | - | assimilation | from API 20NE |
| 68369 | 27689 ChEBI | decanoate | + | assimilation | from API 20NE |
| 68369 | 4853 ChEBI | esculin | + | hydrolysis | from API 20NE |
| 68369 | 5291 ChEBI | gelatin | - | hydrolysis | from API 20NE |
| 68369 | 24265 ChEBI | gluconate | + | assimilation | from API 20NE |
| 68369 | 30849 ChEBI | L-arabinose | - | assimilation | from API 20NE |
| 68369 | 25115 ChEBI | malate | + | assimilation | from API 20NE |
| 68369 | 17306 ChEBI | maltose | - | assimilation | from API 20NE |
| 68369 | 59640 ChEBI | N-acetylglucosamine | + | assimilation | from API 20NE |
| 38746 | 17632 ChEBI | nitrate | + | reduction | |
| 68369 | 17632 ChEBI | nitrate | + | reduction | from API 20NE |
| 38746 | 16301 ChEBI | nitrite | + | reduction | |
| 68369 | 27897 ChEBI | tryptophan | - | energy source | from API 20NE |
| 68369 | 16199 ChEBI | urea | - | hydrolysis | from API 20NE |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 68382 | alkaline phosphatase | + | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | - | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 68369 | arginine dihydrolase | + | 3.5.3.6 | from API 20NE |
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 68382 | beta-glucosidase | - | 3.2.1.21 | from API zym |
| 68369 | beta-glucosidase | + | 3.2.1.21 | from API 20NE |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 38746 | catalase | + | 1.11.1.6 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 68369 | cytochrome oxidase | + | 1.9.3.1 | from API 20NE |
| 68382 | esterase (C 4) | + | from API zym | |
| 68382 | esterase lipase (C 8) | + | from API zym | |
| 68369 | gelatinase | - | from API 20NE | |
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 68382 | lipase (C 14) | - | from API zym | |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 38746 | oxidase | + | ||
| 68382 | trypsin | + | 3.4.21.4 | from API zym |
| 38746 | urease | + | 3.5.1.5 | |
| 68369 | urease | - | 3.5.1.5 | from API 20NE |
| 68382 | valine arylamidase | - | from API zym |
| @ref | Biosafety level | Biosafety level comment | |
|---|---|---|---|
| 38746 | 2 | Risk group (French classification) |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Immunomodulation by extracorporeal ozone-based bactericide system in porcine Pseudomonas aeruginosa septic shock. | Rundgren H, Sjoholm J, Juric S, Janson P, Kolerud J, Wallin R, Skorup P, Lipcsey M, Gunther M. | Sci Rep | 10.1038/s41598-025-07408-5 | 2025 | ||
| Pathogenicity | Monoclonal antibodies derived from B cells in subjects with cystic fibrosis reduce Pseudomonas aeruginosa burden in mice. | Hale M, Takehara KK, Thouvenel CD, Moustafa DA, Repele A, Fontana MF, Netland J, McNamara S, Gibson RL, Goldberg JB, Rawlings DJ, Pepper M. | Elife | 10.7554/elife.98851 | 2025 | |
| Chimeric bacteriocin S5-PmnH engineered by domain swapping efficiently controls Pseudomonas aeruginosa infection in murine keratitis and lung models. | Paskevicius S, Dapkute V, Misiunas A, Balzaris M, Thommes P, Sattar A, Gleba Y, Razanskiene A. | Sci Rep | 10.1038/s41598-022-09865-8 | 2022 | ||
| Functionalization of Bacterial Cellulose with the Antimicrobial Peptide KR-12 via Chimerical Cellulose-Binding Peptides. | van Zyl EM, Coburn JM. | Int J Mol Sci | 10.3390/ijms25031462 | 2024 | ||
| Metabolism | The Pseudomonas aeruginosa protease LasB directly activates IL-1beta. | Sun J, LaRock DL, Skowronski EA, Kimmey JM, Olson J, Jiang Z, O'Donoghue AJ, Nizet V, LaRock CN. | EBioMedicine | 10.1016/j.ebiom.2020.102984 | 2020 | |
| Metabolism | Dual Inhibition of Klebsiella pneumoniae and Pseudomonas aeruginosa Iron Metabolism Using Gallium Porphyrin and Gallium Nitrate. | Choi SR, Britigan BE, Narayanasamy P. | ACS Infect Dis | 10.1021/acsinfecdis.9b00100 | 2019 | |
| Rational Design of a Chimeric Derivative of PcrV as a Subunit Vaccine Against Pseudomonas aeruginosa. | Wan C, Zhang J, Zhao L, Cheng X, Gao C, Wang Y, Xu W, Zou Q, Gu J. | Front Immunol | 10.3389/fimmu.2019.00781 | 2019 | ||
| Metabolism | Iron/Heme Metabolism-Targeted Gallium(III) Nanoparticles Are Active against Extracellular and Intracellular Pseudomonas aeruginosa and Acinetobacter baumannii. | Choi SR, Britigan BE, Narayanasamy P. | Antimicrob Agents Chemother | 10.1128/aac.02643-18 | 2019 | |
| Antibacterial Activities and Antibacterial Mechanism of Polygonum cuspidatum Extracts against Nosocomial Drug-Resistant Pathogens. | Su PW, Yang CH, Yang JF, Su PY, Chuang LY. | Molecules | 10.3390/molecules200611119 | 2015 | ||
| A facile approach for development of a vaccine made of bacterial double-layered membrane vesicles (DMVs). | Wang S, Gao J, Li M, Wang L, Wang Z. | Biomaterials | 10.1016/j.biomaterials.2018.09.042 | 2018 | ||
| Inhaled bacteriophage-loaded polymeric microparticles ameliorate acute lung infections. | Agarwal R, Johnson CT, Imhoff BR, Donlan RM, McCarty NA, Garcia AJ. | Nat Biomed Eng | 10.1038/s41551-018-0263-5 | 2018 | ||
| Pathogenicity | Understanding Pseudomonas aeruginosa-Host Interactions: The Ongoing Quest for an Efficacious Vaccine. | Sainz-Mejias M, Jurado-Martin I, McClean S. | Cells | 10.3390/cells9122617 | 2020 | |
| Synthesis and biological screening of new thiadiazolopyrimidine-based polycyclic compounds. | Alqahtani AM. | Sci Rep | 10.1038/s41598-021-95241-x | 2021 | ||
| Metabolism | Neutrophil-Mediated Delivery of Therapeutic Nanoparticles across Blood Vessel Barrier for Treatment of Inflammation and Infection. | Chu D, Gao J, Wang Z. | ACS Nano | 10.1021/acsnano.5b05583 | 2015 | |
| An engineered human antibody fab fragment specific for Pseudomonas aeruginosa PcrV antigen has potent antibacterial activity. | Baer M, Sawa T, Flynn P, Luehrsen K, Martinez D, Wiener-Kronish JP, Yarranton G, Bebbington C. | Infect Immun | 10.1128/iai.00815-08 | 2009 | ||
| Metabolism | Relating the physical properties of Pseudomonas aeruginosa lipopolysaccharides to virulence by atomic force microscopy. | Ivanov IE, Kintz EN, Porter LA, Goldberg JB, Burnham NA, Camesano TA. | J Bacteriol | 10.1128/jb.01308-10 | 2011 | |
| Pathogenicity | Antimicrobial Activities and Mechanisms of Magnesium Oxide Nanoparticles (nMgO) against Pathogenic Bacteria, Yeasts, and Biofilms. | Nguyen NT, Grelling N, Wetteland CL, Rosario R, Liu H. | Sci Rep | 10.1038/s41598-018-34567-5 | 2018 | |
| Enzymology | Detection of Pseudomonas aeruginosa from clinical and environmental samples by amplification of the exotoxin A gene using PCR. | Khan AA, Cerniglia CE. | Appl Environ Microbiol | 10.1128/aem.60.10.3739-3745.1994 | 1994 | |
| Pathogenicity | Pyocin inhibition of Neisseria gonorrhoeae: mechanism of action. | Morse SA, Jones BV, Lysko PG. | Antimicrob Agents Chemother | 10.1128/aac.18.3.416 | 1980 | |
| Pathogenicity | Interaction with lectins and differential wheat germ agglutinin binding of pyocin 103-sensitive and -resistant Neisseria gonorrhoeae. | Connelly MC, Stein DC, Young FE, Morse SA, Allen PZ. | J Bacteriol | 10.1128/jb.148.3.796-803.1981 | 1981 | |
| Enzymology | Determination of genome size of Pseudomonas aeruginosa by PFGE: analysis of restriction fragments. | Hector JS, Johnson AR | Nucleic Acids Res | 10.1093/nar/18.11.3171 | 1990 |
| #20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 ) |
| #38746 | Collection of Institut Pasteur ; Curators of the CIP; CIP 102967 |
| #50648 | Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 31589 |
| #68369 | Automatically annotated from API 20NE . |
| #68382 | Automatically annotated from API zym . |
| #126262 | A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 ) |
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