Pseudomonas aeruginosa (CIP 104468, ATCC 35151, K 799/61)
Pseudomonas aeruginosa K 799/61 is an obligate aerobe, Gram-negative, motile bacterium of the family Pseudomonadaceae.
Gram-negative motile obligate aerobe BacteriaName and taxonomic classification
| @ref 20215 |
Last LPSN update
2026-05-29 08:38:46 |
| Domain Bacteria |
| Phylum Pseudomonadota |
| Class Gammaproteobacteria |
| Order Pseudomonadales |
| Family Pseudomonadaceae |
| Genus Pseudomonas |
| Species Pseudomonas aeruginosa |
| Full scientific name Pseudomonas aeruginosa (Schroeter 1872) Migula 1900 (Approved Lists 1980) |
| Synonyms (2) |
Physiology and metabolism
Oxygen tolerance
| 35681 | Oxygen toleranceobligate aerobe |
Metabolite utilization
Enzymes
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 35681 | alcohol dehydrogenase | + | 1.1.1.1 | |
| 68382 | alkaline phosphatase | + | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | - | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 35681 | beta-galactosidase | - | 3.2.1.23 | |
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 68382 | beta-glucosidase | - | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 35681 | caseinase | + | 3.4.21.50 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 35681 | DNase | + | ||
| 68382 | esterase (C 4) | + | from API zym | |
| 68382 | esterase lipase (C 8) | + | from API zym | |
| 35681 | gelatinase | + | ||
| 35681 | lecithinase | + | ||
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 35681 | lipase | + | ||
| 68382 | lipase (C 14) | + | from API zym | |
| 35681 | lysine decarboxylase | - | 4.1.1.18 | |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 35681 | ornithine decarboxylase | - | 4.1.1.17 | |
| 35681 | oxidase | + | ||
| 68382 | trypsin | + | 3.4.21.4 | from API zym |
| 35681 | tryptophan deaminase | - | ||
| 35681 | tween esterase | + | ||
| 35681 | urease | + | 3.5.1.5 | |
| 68382 | valine arylamidase | - | from API zym |
API zym
API biotype100
Literature
Literature 
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Penetration through Outer Membrane and Efflux Potential in Pseudomonas aeruginosa of Bulgecin A as an Adjuvant to beta-Lactam Antibiotics. | Kim C, Tomoshige S, Lee M, Zgurskaya HI, Mobashery S. | Antibiotics (Basel) | 10.3390/antibiotics12020358 | 2023 | | |
| Metabolism | Direct measurement of efflux in Pseudomonas aeruginosa using an environment-sensitive fluorescent dye. | Iyer R, Erwin AL. | Res Microbiol | 10.1016/j.resmic.2015.06.006 | 2015 | |
| Pathogenicity | Defects in Efflux (oprM), beta-Lactamase (ampC), and Lipopolysaccharide Transport (lptE) Genes Mediate Antibiotic Hypersusceptibility of Pseudomonas aeruginosa Strain Z61. | Shen X, Johnson NV, Kreamer NNK, Barnes SW, Walker JR, Woods AL, Six DA, Dean CR. | Antimicrob Agents Chemother | 10.1128/aac.00784-19 | 2019 | |
| Pathogenicity | Target (MexB)- and Efflux-Based Mechanisms Decreasing the Effectiveness of the Efflux Pump Inhibitor D13-9001 in Pseudomonas aeruginosa PAO1: Uncovering a New Role for MexMN-OprM in Efflux of beta-Lactams and a Novel Regulatory Circuit (MmnRS) Controlling MexMN Expression. | Ranjitkar S, Jones AK, Mostafavi M, Zwirko Z, Iartchouk O, Barnes SW, Walker JR, Willis TW, Lee PS, Dean CR. | Antimicrob Agents Chemother | 10.1128/aac.01718-18 | 2019 | |
| Pathogenicity | Discovery and Characterization of Chemical Compounds That Inhibit the Function of Aspartyl-tRNA Synthetase from Pseudomonas aeruginosa. | Corona A, Palmer SO, Zamacona R, Mendez B, Dean FB, Bullard JM. | SLAS Discov | 10.1177/2472555217744559 | 2018 | |
| Pathogenicity | Identification of Chemical Compounds That Inhibit Protein Synthesis in Pseudomonas aeruginosa. | Palmer SO, Hu Y, Keniry M, Bullard JM. | SLAS Discov | 10.1177/1087057116679591 | 2017 | |
| Two Forms of Tyrosyl-tRNA Synthetase from Pseudomonas aeruginosa: Characterization and Discovery of Inhibitory Compounds. | Hughes CA, Gorabi V, Escamilla Y, Dean FB, Bullard JM. | SLAS Discov | 10.1177/2472555220934793 | 2020 | | |
| Enzymology | Lysyl-tRNA Synthetase from Pseudomonas aeruginosa: Characterization and Identification of Inhibitory Compounds. | Balboa S, Hu Y, Dean FB, Bullard JM. | SLAS Discov | 10.1177/2472555219873095 | 2020 | |
| Pathogenicity | Identification of Chemical Compounds That Inhibit the Function of Histidyl-tRNA Synthetase from Pseudomonas aeruginosa. | Hu Y, Palmer SO, Robles ST, Resto T, Dean FB, Bullard JM. | SLAS Discov | 10.1177/2472555217722016 | 2018 | |
| Kibdelomycin is a bactericidal broad-spectrum aerobic antibacterial agent. | Singh SB, Dayananth P, Balibar CJ, Garlisi CG, Lu J, Kishii R, Takei M, Fukuda Y, Ha S, Young K. | Antimicrob Agents Chemother | 10.1128/aac.00382-15 | 2015 | | |
| Pathogenicity | Discovery and Analysis of Natural-Product Compounds Inhibiting Protein Synthesis in Pseudomonas aeruginosa. | Hu Y, Keniry M, Palmer SO, Bullard JM. | Antimicrob Agents Chemother | 10.1128/aac.00800-16 | 2016 | |
| Identification of Chemical Compounds That Inhibit the Function of Glutamyl-tRNA Synthetase from Pseudomonas aeruginosa. | Hu Y, Guerrero E, Keniry M, Manrrique J, Bullard JM. | J Biomol Screen | 10.1177/1087057115591120 | 2015 | | |
| Identification and Characterization of a Chemical Compound that Inhibits Methionyl-tRNA Synthetase from Pseudomonas aeruginosa. | Robles S, Hu Y, Resto T, Dean F, Bullard JM. | Curr Drug Discov Technol | 10.2174/1570163814666170330100238 | 2017 | | |
| Enzymology | High Throughput Screen Identifies Natural Product Inhibitor of Phenylalanyl-tRNA Synthetase from Pseudomonas aeruginosa and Streptococcus pneumoniae. | Hu Y, Palmer SO, Munoz H, Bullard JM. | Curr Drug Discov Technol | 10.2174/1570163812666150120154701 | 2014 | |
| Enzymology | Pantethine rescues phosphopantothenoylcysteine synthetase and phosphopantothenoylcysteine decarboxylase deficiency in Escherichia coli but not in Pseudomonas aeruginosa. | Balibar CJ, Hollis-Symynkywicz MF, Tao J. | J Bacteriol | 10.1128/jb.00334-11 | 2011 | |
| Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC. | Erwin AL. | Cold Spring Harb Perspect Med | 10.1101/cshperspect.a025304 | 2016 | | |
| Pathogenicity | Molecular validation of LpxC as an antibacterial drug target in Pseudomonas aeruginosa. | Mdluli KE, Witte PR, Kline T, Barb AW, Erwin AL, Mansfield BE, McClerren AL, Pirrung MC, Tumey LN, Warrener P, Raetz CR, Stover CK. | Antimicrob Agents Chemother | 10.1128/aac.00140-06 | 2006 | |
| High-Throughput Screening of Natural Product and Synthetic Molecule Libraries for Antibacterial Drug Discovery. | Ayon NJ. | Metabolites | 10.3390/metabo13050625 | 2023 | | |
| Metabolism | Identification of elongation factor G as the conserved cellular target of argyrin B. | Nyfeler B, Hoepfner D, Palestrant D, Kirby CA, Whitehead L, Yu R, Deng G, Caughlan RE, Woods AL, Jones AK, Barnes SW, Walker JR, Gaulis S, Hauy E, Brachmann SM, Krastel P, Studer C, Riedl R, Estoppey D, Aust T, Movva NR, Wang Z, Salcius M, Michaud GA, McAllister G, Murphy LO, Tallarico JA, Wilson CJ, Dean CR. | PLoS One | 10.1371/journal.pone.0042657 | 2012 | |
How to cite
If you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive136313.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain dataIsabel Schober, Julia Koblitz, Joaquim Sardà Carbasse, Christian Ebeling, Marvin Leon Schmidt, Adam Podstawka, Rohit Gupta, Vinodh Ilangovan, Javad Chamanara, Jörg Overmann, Lorenz Christian Reimer
Nucleic Acids Research; database issue 2025.
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