Bacillus subtilis natto 3335 UM4 is a human pathogen of the family Bacillaceae.
human pathogen| @ref 20215 |
Last LPSN update
2025-12-16 09:46:59 |
| Domain Bacillati |
| Phylum Bacillota |
| Class Bacilli |
| Order Caryophanales |
| Family Bacillaceae |
| Genus Bacillus |
| Species Bacillus subtilis |
| Full scientific name Bacillus subtilis (Ehrenberg 1835) Cohn 1872 (Approved Lists 1980) |
| Synonyms (1) |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Bacillus subtilis 168 as a unique platform enabling synthesis and dissemination of genomes. | Itaya M | J Gen Appl Microbiol | 10.2323/jgam.2021.12.001 | 2022 |  | |
| Metabolism | A novel method for transforming Geobacillus kaustophilus with a chromosomal segment of Bacillus subtilis transferred via pLS20-dependent conjugation. | Mori K, Fukui K, Amatsu R, Ishikawa S, Verrone V, Wipat A, Meijer WJJ, Yoshida KI | Microb Cell Fact | 10.1186/s12934-022-01759-8 | 2022 | |
| Structural and biochemical characterization of the relaxosome auxiliary proteins encoded on the Bacillus subtilis plasmid pLS20. | Crespo I, Bernardo N, Cuppari A, Calisto BM, Val-Calvo J, Miguel-Arribas A, Meijer WJJ, Carpena X, Gil-Ortiz F, Malfois M, Boer DR | Comput Struct Biotechnol J | 10.1016/j.csbj.2021.12.041 | 2022 | | |
| Establishment Genes Present on pLS20 Family of Conjugative Plasmids Are Regulated in Two Different Ways. | Val-Calvo J, Miguel-Arribas A, Freire F, Abia D, Wu LJ, Meijer WJJ | Microorganisms | 10.3390/microorganisms9122465 | 2021 | | |
| pLS20 is the archetype of a new family of conjugative plasmids harboured by Bacillus species. | Val-Calvo J, Miguel-Arribas A, Abia D, Wu LJ, Meijer WJJ | NAR Genom Bioinform | 10.1093/nargab/lqab096 | 2021 | | |
| Assessment of Bacillus subtilis Plasmid pLS20 Conjugation in the Absence of Quorum Sensing Repression. | Mori K, Verrone V, Amatsu R, Fukui K, Meijer WJJ, Ishikawa S, Wipat A, Yoshida KI | Microorganisms | 10.3390/microorganisms9091931 | 2021 | | |
| Multiple Layered Control of the Conjugation Process of the Bacillus subtilis Plasmid pLS20. | Meijer WJJ, Boer DR, Ares S, Alfonso C, Rojo F, Luque-Ortega JR, Wu LJ | Front Mol Biosci | 10.3389/fmolb.2021.648468 | 2021 | | |
| Genetics | A Conserved Class II Type Thioester Domain-Containing Adhesin Is Required for Efficient Conjugation in Bacillus subtilis. | Gago-Cordoba C, Val-Calvo J, Abia D, Diaz-Talavera A, Miguel-Arribas A, Aguilar Suarez R, van Dijl JM, Wu LJ, Meijer WJJ | mBio | 10.1128/mBio.00104-21 | 2021 | |
| Metabolism | Reversible regulation of conjugation of Bacillus subtilis plasmid pLS20 by the quorum sensing peptide responsive anti-repressor RappLS20. | Singh PK, Serrano E, Ramachandran G, Miguel-Arribas A, Gago-Cordoba C, Val-Calvo J, Lopez-Perez A, Alfonso C, Wu LJ, Luque-Ortega JR, Meijer WJJ | Nucleic Acids Res | 10.1093/nar/gkaa797 | 2020 | |
| Metabolism | Inactivation of the dimeric RappLS20 anti-repressor of the conjugation operon is mediated by peptide-induced tetramerization. | Crespo I, Bernardo N, Miguel-Arribas A, Singh PK, Luque-Ortega JR, Alfonso C, Malfois M, Meijer WJJ, Boer DR | Nucleic Acids Res | 10.1093/nar/gkaa540 | 2020 | |
| Surface Exclusion Revisited: Function Related to Differential Expression of the Surface Exclusion System of Bacillus subtilis Plasmid pLS20. | Gago-Cordoba C, Val-Calvo J, Miguel-Arribas A, Serrano E, Singh PK, Abia D, Wu LJ, Meijer WJJ | Front Microbiol | 10.3389/fmicb.2019.01502 | 2019 | | |
| Biotechnology | Stable mutants of restriction-deficient/modification-proficient Bacillus subtilis 168: hub strains for giant DNA engineering. | Itaya M, Sato M, Watanabe S, Yoshikawa H, Tomita M, Sato R | J Biochem | 10.1093/jb/mvz031 | 2019 | |
| Stable and efficient delivery of DNA to Bacillus subtilis (natto) using pLS20 conjugational transfer plasmids. | Itaya M, Nagasaku M, Shimada T, Ohtani N, Shiwa Y, Yoshikawa H, Kaneko S, Tomita M, Sato M | FEMS Microbiol Lett | 10.1093/femsle/fnz032 | 2019 | | |
| Rapid conjugative mobilization of a 100 kb segment of Bacillus subtilis chromosomal DNA is mediated by a helper plasmid with no ability for self-transfer. | Miyano M, Tanaka K, Ishikawa S, Takenaka S, Miguel-Arribas A, Meijer WJJ, Yoshida KI | Microb Cell Fact | 10.1186/s12934-017-0855-x | 2018 | | |
| Genetics | The first high frequency of recombination-like conjugal transfer from an integrated origin of transfer sequence in Bacillus subtilis 168. | Itaya M, Hasegawa M, Tomita M, Sato M | Biosci Biotechnol Biochem | 10.1080/09168451.2017.1422970 | 2018 | |
| The Bacillus subtilis Conjugative Plasmid pLS20 Encodes Two Ribbon-Helix-Helix Type Auxiliary Relaxosome Proteins That Are Essential for Conjugation. | Miguel-Arribas A, Hao JA, Luque-Ortega JR, Ramachandran G, Val-Calvo J, Gago-Cordoba C, Gonzalez-Alvarez D, Abia D, Alfonso C, Wu LJ, Meijer WJJ | Front Microbiol | 10.3389/fmicb.2017.02138 | 2017 | | |
| Enzymology | Discovery of a new family of relaxases in Firmicutes bacteria. | Ramachandran G, Miguel-Arribas A, Abia D, Singh PK, Crespo I, Gago-Cordoba C, Hao JA, Luque-Ortega JR, Alfonso C, Wu LJ, Boer DR, Meijer WJ | PLoS Genet | 10.1371/journal.pgen.1006586 | 2017 | |
| Induction of Plasmid Conjugation in Bacillus subtilis Is Bistable and Driven by a Direct Interaction of a Rap/Phr Quorum-sensing System with a Master Repressor. | Rosch TC, Graumann PL | J Biol Chem | 10.1074/jbc.M115.664110 | 2015 | | |
| A complex genetic switch involving overlapping divergent promoters and DNA looping regulates expression of conjugation genes of a gram-positive plasmid. | Ramachandran G, Singh PK, Luque-Ortega JR, Yuste L, Alfonso C, Rojo F, Wu LJ, Meijer WJ | PLoS Genet | 10.1371/journal.pgen.1004733 | 2014 | | |
| Diverse regulatory circuits for transfer of conjugative elements. | Singh PK, Meijer WJ | FEMS Microbiol Lett | 10.1111/1574-6968.12526 | 2014 | | |
| Pathogenicity | The presence of conjugative plasmid pLS20 affects global transcription of Its Bacillus subtilis host and confers beneficial stress resistance to cells. | Rosch TC, Golman W, Hucklesby L, Gonzalez-Pastor JE, Graumann PL | Appl Environ Microbiol | 10.1128/AEM.03154-13 | 2013 | |
| Genetics | Mobility of the native Bacillus subtilis conjugative plasmid pLS20 is regulated by intercellular signaling. | Singh PK, Ramachandran G, Ramos-Ruiz R, Peiro-Pastor R, Abia D, Wu LJ, Meijer WJ | PLoS Genet | 10.1371/journal.pgen.1003892 | 2013 | |
| Metabolism | Inhibition of Bacillus subtilis natural competence by a native, conjugative plasmid-encoded comK repressor protein. | Singh PK, Ramachandran G, Duran-Alcalde L, Alonso C, Wu LJ, Meijer WJ | Environ Microbiol | 10.1111/j.1462-2920.2012.02819.x | 2012 | |
| Enzymology | Serial assembly of Thermus megaplasmid DNA in the genome of Bacillus subtilis 168: a BAC-based domino method applied to DNA with a high GC content. | Ohtani N, Hasegawa M, Sato M, Tomita M, Kaneko S, Itaya M | Biotechnol J | 10.1002/biot.201100396 | 2012 | |
| Metabolism | Alp7R regulates expression of the actin-like protein Alp7A in Bacillus subtilis. | Derman AI, Nonejuie P, Michel BC, Truong BD, Fujioka A, Erb ML, Pogliano J | J Bacteriol | 10.1128/JB.06550-11 | 2012 | |
| Metabolism | Localization pattern of conjugation machinery in a Gram-positive bacterium. | Bauer T, Rosch T, Itaya M, Graumann PL | J Bacteriol | 10.1128/JB.00175-11 | 2011 | |
| Genetics | Complete nucleotide sequence and determination of the replication region of the sporulation inhibiting plasmid p576 from Bacillus pumilus NRS576. | Singh PK, Ballestero-Beltran S, Ramachandran G, Meijer WJ | Res Microbiol | 10.1016/j.resmic.2010.07.007 | 2010 | |
| Restriction on conjugational transfer of pLS20 in Bacillus subtilis 168. | Ohtani N, Sato M, Tomita M, Itaya M | Biosci Biotechnol Biochem | 10.1271/bbb.80315 | 2008 | | |
| Enzymology | Conjugational transfer system to shuttle giant DNA cloned by Bacillus subtilis genome (BGM) vector. | Kuroki A, Ohtani N, Tsuge K, Tomita M, Itaya M | Gene | 10.1016/j.gene.2007.04.030 | 2007 | |
| Experimental basis for a stable plasmid, pLS30, to shuttle between Bacillus subtilis species by conjugational transfer. | Sakaya N, Kaneko S, Matsunaga S, Itaya M | J Biochem | 10.1093/jb/mvj058 | 2006 | | |
| Enzymology | Conjugational transfer kinetics of pLS20 between Bacillus subtilis in liquid medium. | Itaya M, Sakaya N, Matsunaga S, Fujita K, Kaneko S | Biosci Biotechnol Biochem | 10.1271/bbb.70.740 | 2006 | |
| Mobilization of "nonmobilizable" plasmids by the aggregation-mediated conjugation system of Bacillus thuringiensis. | Andrup L, Jorgensen O, Wilcks A, Smidt L, Jensen GB | Plasmid | 10.1006/plas.1996.0035 | 1996 | | |
| Metabolism | Identification and characterization of a novel type of replication terminator with bidirectional activity on the Bacillus subtilis theta plasmid pLS20. | Meijer WJ, Smith M, Wake RG, de Boer AL, Venema G, Bron S | Mol Microbiol | 10.1111/j.1365-2958.1996.tb02474.x | 1996 | |
| Genetics | Characterization of the replication region of the Bacillus subtilis plasmid pLS20: a novel type of replicon. | Meijer WJ, de Boer AJ, van Tongeren S, Venema G, Bron S | Nucleic Acids Res | 10.1093/nar/23.16.3214 | 1995 | |
| Genetics | Bacillus subtilis (natto) plasmid pLS20 mediates interspecies plasmid transfer. | Koehler TM, Thorne CB | J Bacteriol | 10.1128/jb.169.11.5271-5278.1987 | 1987 | |
| A New Tool for the Flexible Genetic Manipulation of Geobacillus kaustophilus. | Amatsu R, Mori K, Ishikawa S, Meijer WJJ, Yoshida KI | Bio Protoc | 10.21769/BioProtoc.4502 | 2022 | | |
| Effective plasmid delivery to a plasmid-free Bacillus natto strain by a conjugational transfer system. | Itaya M, Sato M, Watanabe S, Kataoka M | J Biochem | 10.1093/jb/mvac069 | 2022 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive970.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
License