Salmonella enterica subsp. enterica (DSM 24522, SL1344)

Cell morphology

Multimedia

• @ref:	17690
  multimedia content:	DSM_24522.jpg
  multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_24522.jpg
  intellectual property rights:	© Leibniz-Institut DSMZ
  manual_annotation:	1

Culture medium

@ref	Name	Growth	Medium link	Composition
17690	TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)		Medium recipe at MediaDive	Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water
17690	COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)		Medium recipe at MediaDive	Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base

Culture temp

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68368	27613 ChEBI	amygdalin	-	fermentation	from API 20E
68368	29016 ChEBI	arginine	+	hydrolysis	from API 20E
68368	16947 ChEBI	citrate	-	assimilation	from API 20E
68368	17634 ChEBI	D-glucose	+	fermentation	from API 20E
68368	16899 ChEBI	D-mannitol	+	fermentation	from API 20E
68368	5291 ChEBI	gelatin	-	hydrolysis	from API 20E
68368	30849 ChEBI	L-arabinose	+	fermentation	from API 20E
68368	62345 ChEBI	L-rhamnose	+	fermentation	from API 20E
68368	25094 ChEBI	lysine	+	degradation	from API 20E
68368	28053 ChEBI	melibiose	+	fermentation	from API 20E
68368	17268 ChEBI	myo-inositol	-	fermentation	from API 20E
68368	18257 ChEBI	ornithine	+	degradation	from API 20E
68368	30911 ChEBI	sorbitol	+	fermentation	from API 20E
68368	17992 ChEBI	sucrose	-	fermentation	from API 20E
68368	27897 ChEBI	tryptophan	-	energy source	from API 20E
68368	16199 ChEBI	urea	-	hydrolysis	from API 20E

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68368	15688 ChEBI	acetoin		from API 20E
68368	16136 ChEBI	hydrogen sulfide		from API 20E
68368	35581 ChEBI	indole		from API 20E

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Indole test
68368	15688 ChEBI	acetoin	-		from API 20E
68368	35581 ChEBI	indole		-	from API 20E

Enzymes

@ref	Value	Activity	Ec
68368	arginine dihydrolase	+	3.5.3.6	from API 20E
68368	beta-galactosidase	-	3.2.1.23	from API 20E
68368	cytochrome oxidase	-	1.9.3.1	from API 20E
68368	gelatinase	-		from API 20E
68368	lysine decarboxylase	+	4.1.1.18	from API 20E
68368	ornithine decarboxylase	+	4.1.1.17	from API 20E
68368	tryptophan deaminase	-	4.1.99.1	from API 20E
68368	urease	-	3.5.1.5	from API 20E

API 20E

Isolation source categories

Isolation

Risk assessment

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM1612743v1 assembly for Salmonella enterica FDAARGOS_1067	complete	GCA_016127435	28901.13772		28901	98.83
66792	ASM21085v2 assembly for Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344	complete	GCA_000210855	216597.6	2563366604	216597	98.8
66792	ASM2888281v1 assembly for Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344	contig	GCA_028882815	216597.78		216597	72.03
66792	ASM333933v1 assembly for Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344	contig	GCA_003339335	216597.59		216597	69.12

Predictions

Literature

Topic	Title	Authors	Journal	DOI	Year
Genetics	Marine Sponge and Octocoral-Associated Bacteria Show Versatile Secondary Metabolite Biosynthesis Potential and Antimicrobial Activities against Human Pathogens.	Almeida JF, Marques M, Oliveira V, Egas C, Mil-Homens D, Viana R, Cleary DFR, Huang YM, Fialho AM, Teixeira MC, Gomes NCM, Costa R, Keller-Costa T.	Mar Drugs	10.3390/md21010034	2022
	Dietary Modulation Alters Susceptibility to Listeria monocytogenes and Salmonella Typhimurium with or without a Gut Microbiota.	Wolter M, Steimle A, Parrish A, Zimmer J, Desai MS.	mSystems	10.1128/msystems.00717-21	2021
Pathogenicity	Essential role for epithelial HIF-mediated xenophagy in control of Salmonella infection and dissemination.	Dowdell AS, Cartwright IM, Kitzenberg DA, Kostelecky RE, Mahjoob O, Saeedi BJ, Welch N, Glover LE, Colgan SP.	Cell Rep	10.1016/j.celrep.2022.111409	2022
	Insights into the Antimicrobial Activities and Metabolomes of Aquimarina (Flavobacteriaceae, Bacteroidetes) Species from the Rare Marine Biosphere.	Silva SG, Paula P, da Silva JP, Mil-Homens D, Teixeira MC, Fialho AM, Costa R, Keller-Costa T.	Mar Drugs	10.3390/md20070423	2022
	Effects of 405 ± 5-nm LED Illumination on Environmental Stress Tolerance of Salmonella Typhimurium in Sliced Beef.	Guo D, Bai Y, Fei S, Yang Y, Li J, Yang B, Lu X, Xia X, Shi C.	Foods	10.3390/foods11020136	2022
Pathogenicity	Limosilactobacillus reuteri SLZX19-12 Protects the Colon from Infection by Enhancing Stability of the Gut Microbiota and Barrier Integrity and Reducing Inflammation.	Wu J, Lin Z, Wang X, Zhao Y, Zhao J, Liu H, Johnston LJ, Lu L, Ma X	Microbiol Spectr	10.1128/spectrum.02124-21	2022
	Inactivation of Salmonella typhimurium SL1344 by Chlorogenic Acid and the Impairment of Cellular Integrity.	Yang L, Zhang C, Su Z, Zhao L, Wu J, Sun X, Zhang X, Hu X	Front Microbiol	10.3389/fmicb.2022.887950	2022
Enzymology	Tibetan Pig-Derived Probiotic Lactobacillus amylovorus SLZX20-1 Improved Intestinal Function via Producing Enzymes and Regulating Intestinal Microflora.	Shen J, Zhang J, Zhao Y, Lin Z, Ji L, Ma X	Front Nutr	10.3389/fnut.2022.846991	2022
Pathogenicity	Use of bacterial culture supernatants as anti-biofilm agents against Pseudomonas aeruginosa and Klebsiella pneumoniae.	Alghofaili F	Eur Rev Med Pharmacol Sci	10.26355/eurrev_202202_28132	2022
Stress	A Novel LysR Family Factor STM0859 is Associated with The Responses of Salmonella Typhimurium to Environmental Stress and Biofilm Formation.	Ma Z, Li NA, Ning C, Liu Y, Guo Y, Ji C, Zhu X, Meng Q, Xia X, Zhang X, Cai X, Cai K, Jun Q	Pol J Microbiol	10.33073/pjm-2021-045	2021
	Optimized Attenuated Salmonella Typhimurium Suppressed Tumor Growth and Improved Survival in Mice.	Liang K, Zhang R, Luo H, Zhang J, Tian Z, Zhang X, Zhang Y, Ali MK, Kong Q	Front Microbiol	10.3389/fmicb.2021.774490	2021
	Holistic Characterization of a Salmonella Typhimurium Infection Model Using Integrated Molecular Imaging.	Strittmatter N, Kanvatirth P, Inglese P, Race AM, Nilsson A, Dannhorn A, Kudo H, Goldin RD, Ling S, Wong E, Seeliger F, Serra MP, Hoffmann S, Maglennon G, Hamm G, Atkinson J, Jones S, Bunch J, Andren PE, Takats Z, Goodwin RJA, Mastroeni P	J Am Soc Mass Spectrom	10.1021/jasms.1c00240	2021
Pathogenicity	Enhanced Sensitivity of Salmonella to Antimicrobial Blue Light Caused by Inactivating rfaC Gene Involved in Lipopolysaccharide Biosynthesis.	Hu X, Zhang X, Luo S, Wu J, Sun X, Liu M, Wang X, Wang X	Foodborne Pathog Dis	10.1089/fpd.2020.2888	2021
Pathogenicity	Salmonella Typhimurium ST313 isolated in Brazil revealed to be more invasive and inflammatory in murine colon compared to ST19 strains.	Seribelli AA, Ribeiro TRM, da Silva P, Martins IM, Vilela FP, Medeiros MIC, Peronni KC, da Silva Junior WA, Moreira CG, Falcao JP	J Microbiol	10.1007/s12275-021-1082-z	2021
Pathogenicity	Salmonella Effector SpvB Disrupts Intestinal Epithelial Barrier Integrity for Bacterial Translocation.	Sun L, Yang S, Deng Q, Dong K, Li Y, Wu S, Huang R	Front Cell Infect Microbiol	10.3389/fcimb.2020.606541	2020
Phylogeny	Defective apoptotic cell clearance activates innate immune response to protect Caenorhabditis elegans against pathogenic bacteria.	Wan J, Yuan L, Jing H, Zheng Q, Xiao H	Virulence	10.1080/21505594.2020.1857982	2021
	Erratum: Lactobacillus delbrueckii ssp. lactis R4 Prevents Salmonella typhimurium SL1344-Induced Damage to Tight Junctions and Adherens Junctions.	Yu Q, Zhu L, Wang Z, Li P, Yang Q	J Microbiol	10.1007/s12275-020-9726-y	2020
Biotechnology	Phenotypic and genotypic characterization of Salmonella Typhimurium isolates from humans and foods in Brazil.	Seribelli AA, Cruz MF, Vilela FP, Frazao MR, Paziani MH, Almeida F, Medeiros MIC, Rodrigues DDP, Kress MRVZ, Allard MW, Falcao JP	PLoS One	10.1371/journal.pone.0237886	2020
	Salmonella Strain Specificity Determines Post-typhoid Central Nervous System Complications: Intervention by Lactiplantibacillus plantarum at Gut-Brain Axis.	Kaur A, Chopra K, Kaur IP, Rishi P	Front Microbiol	10.3389/fmicb.2020.01568	2020
Pathogenicity	Role of wzxE in Salmonella Typhimurium lipopolysaccharide biosynthesis and interleukin-8 secretion regulation in human intestinal epithelial cells.	Wang KC, Huang CH, Chang PR, Huang MT, Fang SB	Microbiol Res	10.1016/j.micres.2020.126502	2020
	Inflammasome Activation in Bovine Peripheral Blood-Derived Macrophages Is Associated with Actin Rearrangement.	Tahoun A, Jensen K, El-Sharkawy H, Gally D, Rizk AM, Ajarem J, Allam A, Mahmoud AM	Animals (Basel)	10.3390/ani10040655	2020
	Transcriptomic data of Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S treated with novobiocin.	Gogoleva NE, Konnova TA, Balkin AS, Plotnikov AO, Gogolev YV	Data Brief	10.1016/j.dib.2020.105297	2020
Pathogenicity	Activation of apoptosis by Salmonella pathogenicity island-1 effectors through both intrinsic and extrinsic pathways in Salmonella-infected macrophages.	Lin HH, Chen HL, Weng CC, Janapatla RP, Chen CL, Chiu CH	J Microbiol Immunol Infect	10.1016/j.jmii.2020.02.008	2020
Phenotype	Overexpression of RamA, Which Regulates Production of the Multidrug Resistance Efflux Pump AcrAB-TolC, Increases Mutation Rate and Influences Drug Resistance Phenotype.	Grimsey EM, Weston N, Ricci V, Stone JW, Piddock LJV	Antimicrob Agents Chemother	10.1128/AAC.02460-19	2020
	NMR-Metabolomics Shows That BolA Is an Important Modulator of Salmonella Typhimurium Metabolic Processes under Virulence Conditions.	Graca-Lopes G, Graca G, Barahona S, Moreira RN, Arraiano CM, Goncalves LG	Metabolites	10.3390/metabo9110243	2019
Pathogenicity	Enhancing the antibacterial activity of PMAP-37 by increasing its hydrophobicity.	Zhou J, Liu Y, Shen T, Chen L, Zhang C, Cai K, Liu Z, Meng X, Zhang L, Liao C, Wang C	Chem Biol Drug Des	10.1111/cbdd.13601	2019
Pathogenicity	Salmonella Proteomic Profiling during Infection Distinguishes the Intracellular Environment of Host Cells.	Li Z, Liu Y, Fu J, Zhang B, Cheng S, Wu M, Wang Z, Jiang J, Chang C, Liu X	mSystems	10.1128/mSystems.00314-18	2019
Pathogenicity	The composition of a bioprocessed shiitake (Lentinus edodes) mushroom mycelia and rice bran formulation and its antimicrobial effects against Salmonella enterica subsp. enterica serovar Typhimurium strain SL1344 in macrophage cells and in mice.	Kim SP, Lee SJ, Nam SH, Friedman M	BMC Complement Altern Med	10.1186/s12906-018-2365-8	2018
Pathogenicity	Strain-specific properties of Lactobacillus plantarum for prevention of Salmonella infection.	Liu J, Hu D, Chen Y, Huang H, Zhang H, Zhao J, Gu Z, Chen W	Food Funct	10.1039/c8fo00365c	2018
Transcriptome	speG Is Required for Intracellular Replication of Salmonella in Various Human Cells and Affects Its Polyamine Metabolism and Global Transcriptomes.	Fang SB, Huang CJ, Huang CH, Wang KC, Chang NW, Pan HY, Fang HW, Huang MT, Chen CK	Front Microbiol	10.3389/fmicb.2017.02245	2017
Pathogenicity	Identification of a novel gene in ROD9 island of Salmonella Enteritidis involved in the alteration of virulence-associated genes expression.	Das S, Ray S, Ryan D, Sahu B, Suar M	Virulence	10.1080/21505594.2017.1392428	2018
	[Construction and characterization of type III secretion system of attenuated Salmonella typhimurium].	Yu C, Zhai C, Liao C, Yu Z, He L, Jia Y, Li J, Zhang C, Cheng X	Sheng Wu Gong Cheng Xue Bao	10.13345/j.cjb.160143	2016
Pathogenicity	Inflammation boosts bacteriophage transfer between Salmonella spp.	Diard M, Bakkeren E, Cornuault JK, Moor K, Hausmann A, Sellin ME, Loverdo C, Aertsen A, Ackermann M, De Paepe M, Slack E, Hardt WD	Science	10.1126/science.aaf8451	2017
Pathogenicity	Optimisation of Intestinal Fibrosis and Survival in the Mouse S. Typhimurium Model for Anti-fibrotic Drug Discovery and Preclinical Applications.	Johnson LA, Rodansky ES, Moons DS, Larsen SD, Neubig RR, Higgins PDR	J Crohns Colitis	10.1093/ecco-jcc/jjw210	2017
Metabolism	Heterologous Pseudomonas aeruginosa O-antigen delivery using a Salmonella enterica serovar Typhimurium wecA mutant strain.	Bridge DR, Whitmire JM, Makobongo MO, Merrell DS	Int J Med Microbiol	10.1016/j.ijmm.2016.06.005	2016
	Role of yqiC in the Pathogenicity of Salmonella and Innate Immune Responses of Human Intestinal Epithelium.	Wang KC, Huang CH, Ding SM, Chen CK, Fang HW, Huang MT, Fang SB	Front Microbiol	10.3389/fmicb.2016.01614	2016
Proteome	Characterization of the outer membrane subproteome of the virulent strain Salmonella Typhimurium SL1344.	Ferrer-Navarro M, Balleste-Delpierre C, Vila J, Fabrega A	J Proteomics	10.1016/j.jprot.2016.06.032	2016
Pathogenicity	Ciprofloxacin and ceftriaxone alter cytokine responses, but not Toll-like receptors, to Salmonella infection in vitro.	Anuforom O, Wallace GR, Buckner MM, Piddock LJ	J Antimicrob Chemother	10.1093/jac/dkw092	2016
	De Novo sphingolipid synthesis is essential for Salmonella-induced autophagy and human beta-defensin 2 expression in intestinal epithelial cells.	Huang FC	Gut Pathog	10.1186/s13099-016-0088-2	2016
Pathogenicity	[Construction of host-vector balanced lethal system of Salmonella typhimurium SL1344Deltacya mutant and immune protection test of chickling].	Li J, Chen S, Yu Z, He L, Li X, Jia Y, Yu C, Zhang C, Cheng X, Li Y, Wu T, Zhao Z	Wei Sheng Wu Xue Bao		2015
	Contaminated water delivery as a simple and effective method of experimental Salmonella infection.	O'Donnell H, Pham OH, Benoun JM, Ravesloot-Chavez MM, McSorley SJ	Future Microbiol	10.2217/fmb.15.93	2015
Metabolism	An enterobacterial common antigen mutant of Salmonella enterica serovar Typhimurium as a vaccine candidate.	Bridge DR, Whitmire JM, Gilbreath JJ, Metcalf ES, Merrell DS	Int J Med Microbiol	10.1016/j.ijmm.2015.05.004	2015
Metabolism	Complete proteome of a quinolone-resistant Salmonella Typhimurium phage type DT104B clinical strain.	Correia S, Nunes-Miranda JD, Pinto L, Santos HM, de Toro M, Saenz Y, Torres C, Capelo JL, Poeta P, Igrejas G	Int J Mol Sci	10.3390/ijms150814191	2014
Pathogenicity	Antimicrobial and antibiofilm effects of selected food preservatives against Salmonella spp. isolated from chicken samples.	Er B, Demirhan B, Onurdag FK, Ozgacar SO, Oktem AB	Poult Sci	10.3382/ps.2013-03404	2014
Metabolism	Dietary supplementation with white button mushrooms augments the protective immune response to Salmonella vaccine in mice.	Wang J, Niu X, Du X, Smith D, Meydani SN, Wu D	J Nutr	10.3945/jn.113.185165	2013
Phylogeny	Evidence of microevolution of Salmonella Typhimurium during a series of egg-associated outbreaks linked to a single chicken farm.	Hawkey J, Edwards DJ, Dimovski K, Hiley L, Billman-Jacobe H, Hogg G, Holt KE	BMC Genomics	10.1186/1471-2164-14-800	2013
Pathogenicity	A novel role for antibiotic resistance plasmids in facilitating Salmonella adaptation to non-host environments.	Paytubi S, Aznar S, Madrid C, Balsalobre C, Dillon SC, Dorman CJ, Juarez A	Environ Microbiol	10.1111/1462-2920.12244	2013
Stress	Emergence of pulsed electric fields resistance in Salmonella enterica serovar Typhimurium SL1344.	Sagarzazu N, Cebrian G, Pagan R, Condon S, Manas P	Int J Food Microbiol	10.1016/j.ijfoodmicro.2013.07.001	2013
Metabolism	Genetic inactivation of acrAB or inhibition of efflux induces expression of ramA.	Lawler AJ, Ricci V, Busby SJ, Piddock LJ	J Antimicrob Chemother	10.1093/jac/dkt069	2013
Metabolism	Receptor diversity and host interaction of bacteriophages infecting Salmonella enterica serovar Typhimurium.	Shin H, Lee JH, Kim H, Choi Y, Heu S, Ryu S	PLoS One	10.1371/journal.pone.0043392	2012
Pathogenicity	Lactobacillus delbrueckii ssp. lactis R4 prevents Salmonella typhimurium SL1344-induced damage to tight junctions and adherens junctions.	Yu Q, Zhu L, Wang Z, Li P, Yang Q	J Microbiol	10.1007/s12275-012-1596-5	2012
Metabolism	Lactobacillus amylophilus D14 protects tight junction from enteropathogenic bacteria damage in Caco-2 cells.	Yu Q, Wang Z, Yang Q	J Dairy Sci	10.3168/jds.2012-5540	2012
Pathogenicity	Genotypic homogeneity of multidrug resistant S. Typhimurium infecting distinct adult and childhood susceptibility groups in Blantyre, Malawi.	Msefula CL, Kingsley RA, Gordon MA, Molyneux E, Molyneux ME, MacLennan CA, Dougan G, Heyderman RS	PLoS One	10.1371/journal.pone.0042085	2012
	Investigation of antibacterial properties silver nanoparticles prepared via green method.	Shameli K, Ahmad MB, Jazayeri SD, Shabanzadeh P, Sangpour P, Jahangirian H, Gharayebi Y	Chem Cent J	10.1186/1752-153X-6-73	2012
Metabolism	Modification of Salmonella Typhimurium motility by the probiotic yeast strain Saccharomyces boulardii.	Pontier-Bres R, Prodon F, Munro P, Rampal P, Lemichez E, Peyron JF, Czerucka D	PLoS One	10.1371/journal.pone.0033796	2012
Pathogenicity	Motility is critical for effective distribution and accumulation of bacteria in tumor tissue.	Toley BJ, Forbes NS	Integr Biol (Camb)	10.1039/c2ib00091a	2011
Pathogenicity	Lactobacillus acidophilus S-layer protein-mediated inhibition of Salmonella-induced apoptosis in Caco-2 cells.	Li P, Yin Y, Yu Q, Yang Q	Biochem Biophys Res Commun	10.1016/j.bbrc.2011.04.131	2011
Pathogenicity	Partial characterization of bacteriocins produced by two Lactobacilus strains with probiotic properties.	Uymaz B, Akkoc N, Akcelik M	Acta Biol Hung	10.1556/ABiol.61.2011.1.10	2011
Metabolism	Characterisation of proteins extracted from the surface of Salmonella Typhimurium grown under SPI-2-inducing conditions by LC-ESI/MS/MS sequencing.	Sherry AE, Inglis NF, Stevenson A, Fraser-Pitt D, Everest P, Smith DG, Roberts M	Proteomics	10.1002/pmic.200900802	2011
Pathogenicity	Absent bactericidal activity of mouse serum against invasive African nontyphoidal Salmonella results from impaired complement function but not a lack of antibody.	Siggins MK, Cunningham AF, Marshall JL, Chamberlain JL, Henderson IR, MacLennan CA	J Immunol	10.4049/jimmunol.1000284	2011
Stress	Enhanced recovery of Salmonella Typhimurium DT104 from exposure to stress at low temperature.	Humphrey S, Clark LF, Humphrey TJ, Jepson MA	Microbiology (Reading)	10.1099/mic.0.045666-0	2010
Metabolism	Characterization of a novel Salmonella Typhimurium chitinase which hydrolyzes chitin, chitooligosaccharides and an N-acetyllactosamine conjugate.	Larsen T, Petersen BO, Storgaard BG, Duus JO, Palcic MM, Leisner JJ	Glycobiology	10.1093/glycob/cwq174	2010
Metabolism	Avian pathogenic Escherichia coli MT78 invades chicken fibroblasts.	Matter LB, Barbieri NL, Nordhoff M, Ewers C, Horn F	Vet Microbiol	10.1016/j.vetmic.2010.08.006	2010
Pathogenicity	Exposure of Escherichia coli and Salmonella enterica serovar Typhimurium to triclosan induces a species-specific response, including drug detoxification.	Bailey AM, Constantinidou C, Ivens A, Garvey MI, Webber MA, Coldham N, Hobman JL, Wain J, Woodward MJ, Piddock LJ	J Antimicrob Chemother	10.1093/jac/dkp320	2009
Metabolism	Comparison of the immunomodulatory properties of three probiotic strains of Lactobacilli using complex culture systems: prediction for in vivo efficacy.	Mileti E, Matteoli G, Iliev ID, Rescigno M	PLoS One	10.1371/journal.pone.0007056	2009
Pathogenicity	Periplasmic adaptor protein AcrA has a distinct role in the antibiotic resistance and virulence of Salmonella enterica serovar Typhimurium.	Blair JM, La Ragione RM, Woodward MJ, Piddock LJ	J Antimicrob Chemother	10.1093/jac/dkp311	2009
Pathogenicity	Ciprofloxacin selects for multidrug resistance in Salmonella enterica serovar Typhimurium mediated by at least two different pathways.	Ricci V, Piddock LJ	J Antimicrob Chemother	10.1093/jac/dkp054	2009
Proteome	The proteome of Salmonella Typhimurium grown under in vivo-mimicking conditions.	Sonck KA, Kint G, Schoofs G, Vander Wauven C, Vanderleyden J, De Keersmaecker SC	Proteomics	10.1002/pmic.200700476	2009
Metabolism	Deletion of tolA in Salmonella Typhimurium generates an attenuated strain with vaccine potential.	Paterson GK, Northen H, Cone DB, Willers C, Peters SE, Maskell DJ	Microbiology (Reading)	10.1099/mic.0.021576-0	2009
Metabolism	Triclosan resistance in Salmonella enterica serovar Typhimurium.	Webber MA, Randall LP, Cooles S, Woodward MJ, Piddock LJ	J Antimicrob Chemother	10.1093/jac/dkn137	2008
Metabolism	Reactive oxygen species are the major antibacterials against Salmonella Typhimurium purine auxotrophs in the phagosome of RAW 264.7 cells.	Mantena RK, Wijburg OL, Vindurampulle C, Bennett-Wood VR, Walduck A, Drummond GR, Davies JK, Robins-Browne RM, Strugnell RA	Cell Microbiol	10.1111/j.1462-5822.2007.01105.x	2007
Pathogenicity	Commonly used farm disinfectants can select for mutant Salmonella enterica serovar Typhimurium with decreased susceptibility to biocides and antibiotics without compromising virulence.	Randall LP, Cooles SW, Coldham NG, Penuela EG, Mott AC, Woodward MJ, Piddock LJ, Webber MA	J Antimicrob Chemother	10.1093/jac/dkm359	2007
Phylogeny	Tumor-specific colonization, tissue distribution, and gene induction by probiotic Escherichia coli Nissle 1917 in live mice.	Stritzker J, Weibel S, Hill PJ, Oelschlaeger TA, Goebel W, Szalay AA	Int J Med Microbiol	10.1016/j.ijmm.2007.01.008	2007
Pathogenicity	Safety and immunogenicity of attenuated Salmonella enterica serovar Typhimurium delivering an HIV-1 Gag antigen via the Salmonella Type III secretion system.	Kotton CN, Lankowski AJ, Scott N, Sisul D, Chen LM, Raschke K, Borders G, Boaz M, Spentzou A, Galan JE, Hohmann EL	Vaccine	10.1016/j.vaccine.2006.05.094	2006
Metabolism	Identification of Salmonella functions critical for bacterial cell division within eukaryotic cells.	Henry T, Garcia-Del Portillo F, Gorvel JP	Mol Microbiol	10.1111/j.1365-2958.2005.04540.x	2005
Genetics	Induction of cationic chicken liver-expressed antimicrobial peptide 2 in response to Salmonella enterica infection.	Townes CL, Michailidis G, Nile CJ, Hall J	Infect Immun	10.1128/IAI.72.12.6987-6993.2004	2004
Metabolism	Role of the GGDEF protein family in Salmonella cellulose biosynthesis and biofilm formation.	Garcia B, Latasa C, Solano C, Garcia-del Portillo F, Gamazo C, Lasa I	Mol Microbiol	10.1111/j.1365-2958.2004.04269.x	2004
	Interactions between Salmonella typhimurium and Acanthamoeba polyphaga, and observation of a new mode of intracellular growth within contractile vacuoles.	Gaze WH, Burroughs N, Gallagher MP, Wellington EM	Microb Ecol	10.1007/s00248-003-1001-3	2003
Metabolism	Characterization of effector proteins translocated via the SPI1 type III secretion system of Salmonella typhimurium.	Ehrbar K, Mirold S, Friebel A, Stender S, Hardt WD	Int J Med Microbiol	10.1078/1438-4221-00156	2002
Enzymology	Isolation and characterization of a chromosomally encoded disulphide oxidoreductase from Salmonella enterica serovar Typhimurium.	Turcot I, Ponnampalam TV, Bouwman CW, Martin NL	Can J Microbiol		2001
Pathogenicity	Salmonella typhimurium induces apoptosis in human monocyte-derived macrophages.	Zhou X, Mantis N, Zhang XR, Potoka DA, Watkins SC, Ford HR	Microbiol Immunol	10.1111/j.1348-0421.2000.tb02594.x	2000
Phylogeny	Bifidobacterium strains from resident infant human gastrointestinal microflora exert antimicrobial activity.	Lievin V, Peiffer I, Hudault S, Rochat F, Brassart D, Neeser JR, Servin AL	Gut	10.1136/gut.47.5.646	2000
Metabolism	The NRAMP proteins of Salmonella typhimurium and Escherichia coli are selective manganese transporters involved in the response to reactive oxygen.	Kehres DG, Zaharik ML, Finlay BB, Maguire ME	Mol Microbiol	10.1046/j.1365-2958.2000.01922.x	2000
Enzymology	The rpoS-dependent starvation-stress response locus stiA encodes a nitrate reductase (narZYWV) required for carbon-starvation-inducible thermotolerance and acid tolerance in Salmonella typhimurium.	Spector MP, Garcia Del Portillo F, Bearson SMD, Mahmud A, Magut M, Finlay BB, Dougan G, Foster JW, Pallen MJ	Microbiology (Reading)	10.1099/00221287-145-11-3035	1999
Metabolism	Evaluation of Salmonella typhimurium mutants in a model of experimental gastroenteritis.	Everest P, Ketley J, Hardy S, Douce G, Khan S, Shea J, Holden D, Maskell D, Dougan G	Infect Immun	10.1128/IAI.67.6.2815-2821.1999	1999
Pathogenicity	The alternative sigma factor, sigmaE, is critically important for the virulence of Salmonella typhimurium.	Humphreys S, Stevenson A, Bacon A, Weinhardt AB, Roberts M	Infect Immun	10.1128/IAI.67.4.1560-1568.1999	1999
	The virulence plasmid of Salmonella typhimurium is self-transmissible.	Ahmer BM, Tran M, Heffron F	J Bacteriol	10.1128/JB.181.4.1364-1368.1999	1999
Pathogenicity	Escherichia coli O157 interactions with human intestinal Caco-2 cells and the influence of fosfomycin.	Izumikawa K, Hirakata Y, Yamaguchi T, Takemura H, Maesaki S, Tomono K, Igimi S, Kaku M, Yamada Y, Kohno S, Kamihira S	J Antimicrob Chemother	10.1093/jac/42.3.341	1998
Enzymology	The Salmonella typhimurium AhpC polypeptide is not essential for virulence in BALB/c mice but is recognized as an antigen during infection.	Taylor PD, Inchley CJ, Gallagher MP	Infect Immun	10.1128/IAI.66.7.3208-3217.1998	1998
Pathogenicity	The Campylobacter fetus S layer is not essential for initial interaction with HEp-2 cells.	Graham LL, MacDonald KL	Can J Microbiol		1998
Pathogenicity	Trafficking of porin-deficient Salmonella typhimurium mutants inside HeLa cells: ompR and envZ mutants are defective for the formation of Salmonella-induced filaments.	Mills SD, Ruschkowski SR, Stein MA, Finlay BB	Infect Immun	10.1128/IAI.66.4.1806-1811.1998	1998
Metabolism	Virulence of a Salmonella typhimurium OmpD mutant.	Meyer PN, Wilmes-Riesenberg MR, Stathopoulos C, Curtiss R 3rd	Infect Immun	10.1128/IAI.66.1.387-390.1998	1998
	Characterization and immunogenicity of Salmonella typhimurium SL1344 and UK-1 delta crp and delta cdt deletion mutants.	Zhang X, Kelly SM, Bollen WS, Curtiss R 3rd	Infect Immun	10.1128/iai.65.12.5381-5387.1997	1997
	Study of the role of the htrB gene in Salmonella typhimurium virulence.	Jones BD, Nichols WA, Gibson BW, Sunshine MG, Apicella MA	Infect Immun	10.1128/iai.65.11.4778-4783.1997	1997
Phenotype	Mutation of the htrB gene in a virulent Salmonella typhimurium strain by intergeneric transduction: strain construction and phenotypic characterization.	Sunshine MG, Gibson BW, Engstrom JJ, Nichols WA, Jones BD, Apicella MA	J Bacteriol	10.1128/jb.179.17.5521-5533.1997	1997
	Murine salmonellosis studied by confocal microscopy: Salmonella typhimurium resides intracellularly inside macrophages and exerts a cytotoxic effect on phagocytes in vivo.	Richter-Dahlfors A, Buchan AM, Finlay BB	J Exp Med	10.1084/jem.186.4.569	1997
Pathogenicity	Antibacterial effect of the adhering human Lactobacillus acidophilus strain LB.	Coconnier MH, Lievin V, Bernet-Camard MF, Hudault S, Servin AL	Antimicrob Agents Chemother	10.1128/AAC.41.5.1046	1997
	Salmonella typhimurium aroA, htrA, and aroD htrA mutants cause progressive infections in athymic (nu/nu) BALB/c mice.	Sinha K, Mastroeni P, Harrison J, de Hormaeche RD, Hormaeche CE	Infect Immun	10.1128/iai.65.4.1566-1569.1997	1997
Pathogenicity	Promotion of Salmonella typhimurium adherence and membrane ruffling in MDCK epithelia by staurosporine.	Reed KA, Booth TA, Hirst BH, Jepson MA	FEMS Microbiol Lett	10.1111/j.1574-6968.1996.tb08583.x	1996
	Virulence and vaccine potential of Salmonella typhimurium mutants deficient in the expression of the RpoS (sigma S) regulon.	Coynault C, Robbe-Saule V, Norel F	Mol Microbiol	10.1111/j.1365-2958.1996.tb02664.x	1996
Enzymology	Proteome of Salmonella typhimurium SL1344: identification of novel abundant cell envelope proteins and assignment to a two-dimensional reference map.	Qi SY, Moir A, O'Connor CD	J Bacteriol	10.1128/jb.178.16.5032-5038.1996	1996
	Evidence for a rapid, direct effect on epithelial monolayer integrity and transepithelial transport in response to Salmonella invasion.	Jepson MA, Lang TF, Reed KA, Simmons NL	Pflugers Arch	10.1007/s004240050128	1996
Enzymology	Identification of a Salmonella virulence gene required for formation of filamentous structures containing lysosomal membrane glycoproteins within epithelial cells.	Stein MA, Leung KY, Zwick M, Garcia-del Portillo F, Finlay BB	Mol Microbiol	10.1111/j.1365-2958.1996.tb02497.x	1996
Enzymology	Rapid disruption of epithelial barrier function by Salmonella typhimurium is associated with structural modification of intercellular junctions.	Jepson MA, Collares-Buzato CB, Clark MA, Hirst BH, Simmons NL	Infect Immun	10.1128/iai.63.1.356-359.1995	1995
Pathogenicity	Comparison of Salmonella typhi and Salmonella typhimurium invasion, intracellular growth and localization in cultured human epithelial cells.	Mills SD, Finlay BB	Microb Pathog	10.1006/mpat.1994.1086	1994
Genetics	Identification and characterization of a Salmonella typhimurium oxygen-regulated gene required for bacterial internalization.	Jones BD, Falkow S	Infect Immun	10.1128/iai.62.9.3745-3752.1994	1994
Phenotype	Role of hns in the virulence phenotype of pathogenic salmonellae.	Harrison JA, Pickard D, Higgins CF, Khan A, Chatfield SN, Ali T, Dorman CJ, Hormaeche CE, Dougan G	Mol Microbiol	10.1111/j.1365-2958.1994.tb00408.x	1994
Pathogenicity	Effects of multiplicity of infection, bacterial protein synthesis, and growth phase on adhesion to and invasion of human cell lines by Salmonella typhimurium.	Kusters JG, Mulders-Kremers GA, van Doornik CE, van der Zeijst BA	Infect Immun	10.1128/iai.61.12.5013-5020.1993	1993
Enzymology	Light emission from a Mudlux transcriptional fusion in Salmonella typhimurium is stimulated by hydrogen peroxide and by interaction with the mouse macrophage cell line J774.2.	Francis KP, Gallagher MP	Infect Immun	10.1128/iai.61.2.640-649.1993	1993
Enzymology	Impaired resistance to infection does not increase the virulence of Salmonella htrA live vaccines for mice.	Strahan K, Chatfield SN, Tite J, Dougan G, Hormaeche CE	Microb Pathog	10.1016/0882-4010(92)90049-t	1992
Enzymology	Evaluation of Salmonella typhimurium strains harbouring defined mutations in htrA and aroA in the murine salmonellosis model.	Chatfield SN, Strahan K, Pickard D, Charles IG, Hormaeche CE, Dougan G	Microb Pathog	10.1016/0882-4010(92)90117-7	1992
Pathogenicity	Intracellular replication is essential for the virulence of Salmonella typhimurium.	Leung KY, Finlay BB	Proc Natl Acad Sci U S A	10.1073/pnas.88.24.11470	1991
	The involvement of tumor necrosis factor in immunity to Salmonella infection.	Tite JP, Dougan G, Chatfield SN	J Immunol		1991
	Role of ompR-dependent genes in Salmonella typhimurium virulence: mutants deficient in both ompC and ompF are attenuated in vivo.	Chatfield SN, Dorman CJ, Hayward C, Dougan G	Infect Immun	10.1128/iai.59.1.449-452.1991	1991
	Salmonella typhimurium mutants lacking flagella or motility remain virulent in BALB/c mice.	Lockman HA, Curtiss R 3rd	Infect Immun	10.1128/iai.58.1.137-143.1990	1990
	Characterization of porin and ompR mutants of a virulent strain of Salmonella typhimurium: ompR mutants are attenuated in vivo.	Dorman CJ, Chatfield S, Higgins CF, Hayward C, Dougan G	Infect Immun	10.1128/iai.57.7.2136-2140.1989	1989
	Virulence and vaccine potential of phoP mutants of Salmonella typhimurium.	Galan JE, Curtiss R 3rd	Microb Pathog	10.1016/0882-4010(89)90085-5	1989
Enzymology	Construction and characterization of vaccine strains of Salmonella harboring mutations in two different aro genes.	Dougan G, Chatfield S, Pickard D, Bester J, O'Callaghan D, Maskell D	J Infect Dis	10.1093/infdis/158.6.1329	1988
	Protective immunity evoked by oral administration of attenuated aroA Salmonella typhimurium expressing cloned streptococcal M protein.	Poirier TP, Kehoe MA, Beachey EH	J Exp Med	10.1084/jem.168.1.25	1988
Cultivation	Plasmid-associated virulence of Salmonella typhimurium.	Gulig PA, Curtiss R 3rd	Infect Immun	10.1128/iai.55.12.2891-2901.1987	1987
Pathogenicity	Salmonella typhimurium aroA mutants as carriers of the Escherichia coli heat-labile enterotoxin B subunit to the murine secretory and systemic immune systems.	Maskell DJ, Sweeney KJ, O'Callaghan D, Hormaeche CE, Liew FY, Dougan G	Microb Pathog	10.1016/0882-4010(87)90022-2	1987
Enzymology	In vivo properties of a cloned K88 adherence antigen determinant.	Dougan G, Sellwood R, Maskell D, Sweeney K, Liew FY, Beesley J, Hormaeche C	Infect Immun	10.1128/iai.52.1.344-347.1986	1986