Klebsiella pneumoniae CIP 110798 is an aerobe, Gram-negative, rod-shaped bacterium that was isolated from Derived from ATCC 15380.
Gram-negative rod-shaped aerobe genome sequence Bacteria| @ref 20215 |
Last LPSN update
2026-05-29 08:39:29 |
| Domain Bacteria |
| Phylum Pseudomonadota |
| Class Gammaproteobacteria |
| Order Enterobacterales |
| Family Enterobacteriaceae |
| Genus Klebsiella |
| Species Klebsiella pneumoniae |
| Full scientific name Klebsiella pneumoniae (Schroeter 1886) Trevisan 1887 (Approved Lists 1980) |
| Synonyms (1) |
| 46983 | Oxygen toleranceaerobe |
| @ref | Spore formation | Confidence | |
|---|---|---|---|
| 125439 | 96.918 |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68374 | 29016 ChEBI | arginine | - | hydrolysis | from API ID32E |
| 68374 | 17057 ChEBI | cellobiose | + | builds acid from | from API ID32E |
| 68374 | 18333 ChEBI | D-arabitol | + | builds acid from | from API ID32E |
| 68374 | 18024 ChEBI | D-galacturonic acid | - | builds acid from | from API ID32E |
| 68374 | 17634 ChEBI | D-glucose | + | builds acid from | from API ID32E |
| 68374 | 16899 ChEBI | D-mannitol | + | builds acid from | from API ID32E |
| 68374 | 30849 ChEBI | L-arabinose | + | builds acid from | from API ID32E |
| 68374 | 18403 ChEBI | L-arabitol | - | builds acid from | from API ID32E |
| 68374 | 62345 ChEBI | L-rhamnose | + | builds acid from | from API ID32E |
| 68374 | 25094 ChEBI | lysine | + | degradation | from API ID32E |
| 68374 | 15792 ChEBI | malonate | + | assimilation | from API ID32E |
| 68374 | 17306 ChEBI | maltose | + | builds acid from | from API ID32E |
| 68374 | 17268 ChEBI | myo-inositol | + | builds acid from | from API ID32E |
| 68374 | 18257 ChEBI | ornithine | - | degradation | from API ID32E |
| 68374 | 18394 ChEBI | palatinose | + | builds acid from | from API ID32E |
| 68374 | 0 ChEBI | Potassium 5-ketogluconate | - | builds acid from | from API ID32E |
| 68374 | 15963 ChEBI | ribitol | + | builds acid from | from API ID32E |
| 68374 | 30911 ChEBI | sorbitol | + | builds acid from | from API ID32E |
| 68374 | 17992 ChEBI | sucrose | + | builds acid from | from API ID32E |
| 68374 | 27082 ChEBI | trehalose | + | builds acid from | from API ID32E |
| 68374 | 27897 ChEBI | tryptophan | - | energy source | from API ID32E |
| 68374 | 16199 ChEBI | urea | + | hydrolysis | from API ID32E |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68374 | alpha-galactosidase | + | 3.2.1.22 | from API ID32E |
| 68374 | alpha-glucosidase | - | 3.2.1.20 | from API ID32E |
| 68374 | alpha-maltosidase | - | from API ID32E | |
| 68374 | arginine dihydrolase | - | 3.5.3.6 | from API ID32E |
| 68374 | beta-galactosidase | + | 3.2.1.23 | from API ID32E |
| 68374 | beta-glucosidase | + | 3.2.1.21 | from API ID32E |
| 68374 | beta-glucuronidase | - | 3.2.1.31 | from API ID32E |
| 68374 | L-aspartate arylamidase | - | 3.4.11.21 | from API ID32E |
| 68374 | lipase | - | from API ID32E | |
| 68374 | lysine decarboxylase | + | 4.1.1.18 | from API ID32E |
| 68374 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API ID32E |
| 68374 | ornithine decarboxylase | - | 4.1.1.17 | from API ID32E |
| 68374 | urease | + | 3.5.1.5 | from API ID32E |
| @ref | ODC | ADH (Arg) | LDC (Lys) | URE | LARL | GAT | 5KG | LipaseLIP | Phenol red (Acidification)RP | beta GLU | MAN | MAL | ADO | PLE | beta GUR | MNT | IND | N-Acetyl-beta-Glucosaminidasebeta NAG | beta GAL | GLU | SAC | LARA | DARL | alpha GLU | alpha GAL | TRE | RHA | INO | CEL | SOR | alpha-MaltosidasealphaMAL | L-aspartic acid arylamidaseAspA | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 46983 | - | - | + | + | - | - | - | - | - | + | + | + | + | + | - | + | - | - | + | + | + | + | + | - | + | + | + | + | + | + | - | - |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|
| 66792 | 38732_E01 assembly for Klebsiella pneumoniae NCTC11228 | contig | GCA_900451865   | 573.20149  | 573 | 76.63 | |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Physiochemical characterization of a potential Klebsiella phage MKP-1 and analysis of its application in reducing biofilm formation. | Das S, Kaledhonkar S. | Front Microbiol | 10.3389/fmicb.2024.1397447 | 2024 | | |
| From Nature to Nurture: The Science and Applications of Snail Slime in Health and Beauty. | Rashad M, Sampo S, Cataldi A, Zara S. | J Cosmet Dermatol | 10.1111/jocd.70002 | 2025 | | |
| Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria. | Bakker AT, Kotsogianni I, Avalos M, Punt JM, Liu B, Piermarini D, Gagestein B, Slingerland CJ, Zhang L, Willemse JJ, Ghimire LB, van den Berg RJHBN, Janssen APA, Ottenhoff THM, van Boeckel CAA, van Wezel GP, Ghilarov D, Martin NI, van der Stelt M. | Nat Chem | 10.1038/s41557-024-01516-x | 2024 | | |
| Antimicrobial activity of essential oils of cultivated oregano (Origanum vulgare), sage (Salvia officinalis), and thyme (Thymus vulgaris) against clinical isolates of Escherichia coli, Klebsiella oxytoca, and Klebsiella pneumoniae. | Fournomiti M, Kimbaris A, Mantzourani I, Plessas S, Theodoridou I, Papaemmanouil V, Kapsiotis I, Panopoulou M, Stavropoulou E, Bezirtzoglou EE, Alexopoulos A. | Microb Ecol Health Dis | 10.3402/mehd.v26.23289 | 2015 | | |
| Metabolism | Piperacillin-tazobactam penetration into human pancreatic juice. | Bertazzoni Minelli E, Benini A, Franco L, Bassi C, Pederzoli P. | Antimicrob Agents Chemother | 10.1128/aac.00509-08 | 2008 | |
| Enzymology | Rapid identification of Burkholderia pseudomallei by latex agglutination based on an exopolysaccharide-specific monoclonal antibody. | Steinmetz I, Reganzerowski A, Brenneke B, Haussler S, Simpson A, White NJ. | J Clin Microbiol | 10.1128/jcm.37.1.225-228.1999 | 1999 | |
| Postantibiotic and post-beta-lactamase inhibitor effects of amoxicillin plus clavulanate. | Thorburn CE, Molesworth SJ, Sutherland R, Rittenhouse S. | Antimicrob Agents Chemother | 10.1128/aac.40.12.2796 | 1996 | | |
| Pathogenicity | Efficacy of simulated cefditoren versus amoxicillin-clavulanate free concentrations in countering intrastrain ftsI gene diffusion in Haemophilus influenzae. | Gonzalez N, Aguilar L, Sevillano D, Gimenez MJ, Alou L, Cafini F, Torrico M, Lopez AM, Coronel P, Prieto J. | Antimicrob Agents Chemother | 10.1128/aac.01719-10 | 2011 | |
| Pathogenicity | influence of TEM-1 beta-lactamase on the pharmacodynamic activity of simulated total versus free-drug serum concentrations of cefditoren (400 milligrams) versus amoxicillin-clavulanic acid (2,000/125 milligrams) against Haemophilus influenzae strains exhibiting an N526K mutation in the ftsI gene. | Torrico M, Aguilar L, Gonzalez N, Gimenez MJ, Echeverria O, Cafini F, Sevillano D, Alou L, Coronel P, Prieto J. | Antimicrob Agents Chemother | 10.1128/aac.01530-06 | 2007 | |
| Beta-lactam effects on mixed cultures of common respiratory isolates as an approach to treatment effects on nasopharyngeal bacterial population dynamics. | Sevillano D, Aguilar L, Alou L, Gimenez MJ, Gonzalez N, Torrico M, Cafini F, Coronel P, Prieto J. | PLoS One | 10.1371/journal.pone.0003846 | 2008 | | |
| Enzymology | Simulation of human serum pharmacokinetics of ticarcillin-clavulanic acid and ceftazidime in rabbits, and efficacy against experimental Klebsiella pneumoniae meningitis. | Mizen L, Woodnutt G, Kernutt I, Catherall EJ. | Antimicrob Agents Chemother | 10.1128/aac.33.5.693 | 1989 | |
| Efficacy of high-dose amoxicillin-clavulanate against experimental respiratory tract infections caused by strains of Streptococcus pneumoniae. | Woodnutt G, Berry V. | Antimicrob Agents Chemother | 10.1128/aac.43.1.35 | 1999 | | |
| Pathogenicity | Bactericidal effects of ticarcillin-clavulanic acid against beta-lactamase-producing bacteria in vivo. | Boon RJ, Beale AS, Sutherland R. | Antimicrob Agents Chemother | 10.1128/aac.29.5.838 | 1986 | |
| Two pharmacodynamic models for assessing the efficacy of amoxicillin-clavulanate against experimental respiratory tract infections caused by strains of Streptococcus pneumoniae. | Woodnutt G, Berry V. | Antimicrob Agents Chemother | 10.1128/aac.43.1.29 | 1999 | | |
| Preincisional intraparietal Augmentin in abdominal operations. | Pollock AV, Evans M, Smith GM. | Ann R Coll Surg Engl | 1989 | | ||
| Pathogenicity | Comparative bacteriological efficacy of pharmacokinetically enhanced amoxicillin-clavulanate against Streptococcus pneumoniae with elevated amoxicillin MICs and Haemophilus influenzae. | Berry V, Hoover J, Singley C, Woodnutt G. | Antimicrob Agents Chemother | 10.1128/aac.49.3.908-915.2005 | 2005 | |
| Relevance of Chlamydia pneumoniae murine pneumonitis model to evaluation of antimicrobial agents. | Masson ND, Toseland CD, Beale AS. | Antimicrob Agents Chemother | 10.1128/aac.39.9.1959 | 1995 | | |
| Pharmacokinetics of amoxycillin and clavulanic acid in haemodialysis patients following intravenous administration of Augmentin. | Davies BE, Boon R, Horton R, Reubi FC, Descoeudres CE. | Br J Clin Pharmacol | 10.1111/j.1365-2125.1988.tb03395.x | 1988 | | |
| Pathogenicity | Bacteriological efficacies of three macrolides compared with those of amoxicillin-clavulanate against Streptococcus pneumoniae and Haemophilus influenzae. | Berry V, Thorburn CE, Knott SJ, Woodnutt G. | Antimicrob Agents Chemother | 10.1128/aac.42.12.3193 | 1998 | |
| Influence of clavulanic acid on the activity of amoxicillin against an experimental Streptococcus pneumoniae-Staphylococcus aureus mixed respiratory infection. | Smith GM, Boon RJ, Beale AS. | Antimicrob Agents Chemother | 10.1128/aac.34.2.210 | 1990 | | |
| Enzymology | Purification and characterization of an exopolysaccharide of Burkholderia (Pseudomonas) pseudomallei. | Steinmetz I, Rohde M, Brenneke B. | Infect Immun | 10.1128/iai.63.10.3959-3965.1995 | 1995 | |
| Pathogenicity | In vitro activities of oral beta-lactams at concentrations achieved in humans against penicillin-susceptible and -resistant pneumococci and potential to select resistance. | Thorburn CE, Knott SJ, Edwards DI. | Antimicrob Agents Chemother | 10.1128/aac.42.8.1973 | 1998 | |
| Enzymology | Pharmacokinetics and distribution of ticarcillin-clavulanic acid (Timentin) in experimental animals. | Woodnutt G, Kernutt I, Mizen L. | Antimicrob Agents Chemother | 10.1128/aac.31.11.1826 | 1987 | |
| Semisynthetic blasticidin S ester derivatives show enhanced antibiotic activity. | Gannett C, Banks P, Chuong C, Weger-Lucarelli J, Mevers E, Lowell AN. | RSC Med Chem | 10.1039/d2md00412g | 2023 | | |
| Purification, Characterization and in vitro Evaluation of Polymyxin A From Paenibacillus dendritiformis: An Underexplored Member of the Polymyxin Family. | Jangra M, Randhawa HK, Kaur M, Srivastava A, Maurya N, Patil PP, Jaswal P, Arora A, Patil PB, Raje M, Nandanwar H. | Front Microbiol | 10.3389/fmicb.2018.02864 | 2018 | | |
| Enzymology | Homologous expression of lysA encoding diaminopimelic acid (DAP) decarboxylase reveals increased antibiotic production in Streptomyces clavuligerus. | Otur C, Kurt-Kizildogan A. | Braz J Microbiol | 10.1007/s42770-019-00202-2 | 2020 | |
| High-Resolution Comparative and Quantitative Proteomics of Biogenic-Amine-Producing Bacteria and Virulence Factors Present in Seafood. | Abril AG, Calo-Mata P, Villa TG, Bohme K, Barros-Velazquez J, Sanchez-Perez A, Pazos M, Carrera M. | J Agric Food Chem | 10.1021/acs.jafc.3c06607 | 2024 | | |
| Organic Extract of Justicia pectoralis Jacq. Leaf Inhibits Interferon-gamma Secretion and Has Bacteriostatic Activity against Acinetobacter baumannii and Klebsiella pneumoniae. | Nunes TRS, Cordeiro MF, Beserra FG, de Souza ML, da Silva WAV, Ferreira MRA, Soares LAL, Costa-Junior SD, Cavalcanti IMF, Pitta MGDR, Pitta IDR, Rego MJBM. | Evid Based Complement Alternat Med | 10.1155/2018/5762368 | 2018 | | |
| Antimicrobial, Antivirulence, and Antiparasitic Potential of Capsicum chinense Jacq. Extracts and Their Isolated Compound Capsaicin. | Menezes RP, Bessa MAS, Siqueira CP, Teixeira SC, Ferro EAV, Martins MM, Cunha LCS, Martins CHG. | Antibiotics (Basel) | 10.3390/antibiotics11091154 | 2022 | | |
| Green Extracellular Synthesis of Silver Nanoparticles by Pseudomonas alloputida, Their Growth and Biofilm-Formation Inhibitory Activities and Synergic Behavior with Three Classical Antibiotics. | Pernas-Pleite C, Conejo-Martinez AM, Marin I, Abad JP. | Molecules | 10.3390/molecules27217589 | 2022 | | |
| Microalga Broths Synthesize Antibacterial and Non-Cytotoxic Silver Nanoparticles Showing Synergy with Antibiotics and Bacterial ROS Induction and Can Be Reused for Successive AgNP Batches. | Pernas-Pleite C, Conejo-Martinez AM, Fernandez Freire P, Hazen MJ, Marin I, Abad JP. | Int J Mol Sci | 10.3390/ijms242216183 | 2023 | | |
| Silver Nanoparticles (AgNPs) from Lysinibacillus sp. Culture Broths: Antibacterial Activity, Mechanism Insights, and Synergy with Classical Antibiotics. | Pernas-Pleite C, Conejo-Martinez AM, Marin I, Abad JP. | Biomolecules | 10.3390/biom15050731 | 2025 | | |
| Antimicrobial and radical scavenging properties of bovine collagen hydrolysates produced by Penicillium aurantiogriseum URM 4622 collagenase. | Lima CA, Campos JF, Filho JL, Converti A, da Cunha MG, Porto AL. | J Food Sci Technol | 10.1007/s13197-014-1463-y | 2015 | | |
| Pathogenicity | A Novel Microfluidic Assay for Rapid Phenotypic Antibiotic Susceptibility Testing of Bacteria Detected in Clinical Blood Cultures. | Malmberg C, Malmberg C, Yuen P, Spaak J, Cars O, Tangden T, Lagerback P. | PLoS One | 10.1371/journal.pone.0167356 | 2016 | |
| Brazilian Theraphosidae: a toxicological point of view. | Macedo KWR, Costa LJL, de Souza JO, de Vasconcelos IA, de Castro JS, de Santana CJC, Magalhaes ACM, Castro MS, Pires OR. | J Venom Anim Toxins Incl Trop Dis | 10.1590/1678-9199-jvatitd-2021-0004 | 2021 | | |
| Pathogenicity | Tridecaptin M, a New Variant Discovered in Mud Bacterium, Shows Activity against Colistin- and Extremely Drug-Resistant Enterobacteriaceae. | Jangra M, Kaur M, Tambat R, Rana R, Maurya SK, Khatri N, Ghafur A, Nandanwar H. | Antimicrob Agents Chemother | 10.1128/aac.00338-19 | 2019 | |
| Evaluation of Antibacterial, Antineoplastic, and Immunomodulatory Activity of Paullinia cupana Seeds Crude Extract and Ethyl-Acetate Fraction. | Carvalho LV, Cordeiro MF, E Lins TU, Sampaio MC, de Mello GS, da Costa VC, Marques LL, Klein T, de Mello JC, Cavalcanti IM, Pitta ID, Galdino da Rocha Pitta M, Rego MJ. | Evid Based Complement Alternat Med | 10.1155/2016/1203274 | 2016 | | |
| Chemical composition and antimicrobial activity of the essential oil from Ambrosia trifida L. | Wang P, Kong CH, Zhang CX. | Molecules | 10.3390/11070549 | 2006 | | |
| Pathogenicity | In vitro activity and in vivo efficacy of clavulanic acid against Acinetobacter baumannii. | Beceiro A, Lopez-Rojas R, Dominguez-Herrera J, Docobo-Perez F, Bou G, Pachon J, Spanish Network for Research in Infectious Diseases (REIPI). | Antimicrob Agents Chemother | 10.1128/aac.00320-09 | 2009 | |
| Enzymology | Transcriptional Studies on a Streptomyces clavuligerus oppA2 Deletion Mutant: N-Acetylglycyl-Clavaminic Acid Is an Intermediate of Clavulanic Acid Biosynthesis. | Alvarez-Alvarez R, Rodriguez-Garcia A, Martinez-Burgo Y, Martin JF, Liras P. | Appl Environ Microbiol | 10.1128/aem.01701-18 | 2018 | |
| Pathogenicity | Risk factors for colonization and infection in a hospital outbreak caused by a strain of Klebsiella pneumoniae with reduced susceptibility to expanded-spectrum cephalosporins. | Cartelle M, del Mar Tomas M, Pertega S, Beceiro A, Dominguez MA, Velasco D, Molina F, Villanueva R, Bou G. | J Clin Microbiol | 10.1128/jcm.42.9.4242-4249.2004 | 2004 | |
| Enzymology | An allelic variant of the chromosomal gene for class A beta-lactamase K2, specific for Klebsiella pneumoniae, is the ancestor of SHV-1. | Haeggman S, Lofdahl S, Burman LG. | Antimicrob Agents Chemother | 10.1128/aac.41.12.2705 | 1997 | |
| Bioactive Marine Xanthones: A Review. | Soares JX, Loureiro DRP, Dias AL, Reis S, Pinto MMM, Afonso CMM. | Mar Drugs | 10.3390/md20010058 | 2022 | | |
| Inoculum effect on the efficacies of amoxicillin-clavulanate, piperacillin-tazobactam, and imipenem against extended-spectrum beta-lactamase (ESBL)-producing and non-ESBL-producing Escherichia coli in an experimental murine sepsis model. | Docobo-Perez F, Lopez-Cerero L, Lopez-Rojas R, Egea P, Dominguez-Herrera J, Rodriguez-Bano J, Pascual A, Pachon J. | Antimicrob Agents Chemother | 10.1128/aac.02190-12 | 2013 | | |
| Enzymology | Role of coagulase in a murine model of hematogenous pulmonary infection induced by intravenous injection of Staphylococcus aureus enmeshed in agar beads. | Sawai T, Tomono K, Yanagihara K, Yamamoto Y, Kaku M, Hirakata Y, Koga H, Tashiro T, Kohno S. | Infect Immun | 10.1128/iai.65.2.466-471.1997 | 1997 | |
| Structures, Activities and Drug-Likeness of Anti-Infective Xanthone Derivatives Isolated from the Marine Environment: A Review. | Loureiro DRP, Soares JX, Costa JC, Magalhaes AF, Azevedo CMG, Pinto MMM, Afonso CMM. | Molecules | 10.3390/molecules24020243 | 2019 | | |
| Enzymology | Selective medium for the isolation and enumeration of Klebsiella spp. | Wong SH, Cullimore DR, Bruce DL. | Appl Environ Microbiol | 10.1128/aem.49.4.1022-1024.1985 | 1985 | |
| Stability of amoxicillin-clavulanate in BACTEC medium determined by high-performance liquid chromatography and bioassay. | Moore TD, Horton R, Utrup LJ, Miller LA, Poupard JA. | J Clin Microbiol | 10.1128/jcm.34.5.1321-1322.1996 | 1996 | | |
| Phylogeny | Evaluation of the Wider system, a new computer-assisted image-processing device for bacterial identification and susceptibility testing. | Canton R, Perez-Vazquez M, Oliver A, Sanchez Del Saz B, Gutierrez MO, Martinez-Ferrer M, Baquero F. | J Clin Microbiol | 10.1128/jcm.38.4.1339-1346.2000 | 2000 | |
| Metabolism | A rhodanese-like protein is highly overrepresented in the mutant S. clavuligerus oppA2::aph: effect on holomycin and other secondary metabolites production. | Nardiz N, Santamarta I, Lorenzana LM, Martin JF, Liras P. | Microb Biotechnol | 10.1111/j.1751-7915.2010.00222.x | 2011 | |
| Pathogenicity | In vitro pharmacodynamic studies of L-749,345 in comparison with imipenem and ceftriaxone against gram-positive and gram-negative bacteria. | Odenholt I, Lowdin E, Cars O. | Antimicrob Agents Chemother | 10.1128/aac.42.9.2365 | 1998 | |
| Metabolism | Identification and characterization of the carbapenem MM 4550 and its gene cluster in Streptomyces argenteolus ATCC 11009. | Li R, Lloyd EP, Moshos KA, Townsend CA. | Chembiochem | 10.1002/cbic.201300319 | 2014 | |
| Pathogenicity | Bactericidal activity against Haemophilus influenzae of cerebrospinal fluid of patients given amoxicillin-clavulanic acid. | Decazes JM, Bure A, Wolff M, Kitzis MD, Pangon B, Modai J. | Antimicrob Agents Chemother | 10.1128/aac.31.12.2018 | 1987 | |
| Alanylclavam biosynthetic genes are clustered together with one group of clavulanic acid biosynthetic genes in Streptomyces clavuligerus. | Zelyas NJ, Cai H, Kwong T, Jensen SE. | J Bacteriol | 10.1128/jb.00698-08 | 2008 | | |
| Metabolism | Pharmacokinetics of potassium clavulanate in combination with amoxicillin in pediatric patients. | Nelson JD, Kusmiesz H, Shelton S. | Antimicrob Agents Chemother | 10.1128/aac.21.4.681 | 1982 | |
| Characterization of the Streptomyces clavuligerus argC gene encoding N-acetylglutamyl-phosphate reductase: expression in Streptomyces lividans and effect on clavulanic acid production. | Ludovice M, Martin JF, Carrachas P, Liras P. | J Bacteriol | 10.1128/jb.174.14.4606-4613.1992 | 1992 | | |
| Metabolism | Concentration of amoxycillin and clavulanate in lung compartments in adults without pulmonary infection. | Cook PJ, Andrews JM, Woodcock J, Wise R, Honeybourne D. | Thorax | 10.1136/thx.49.11.1134 | 1994 | |
| Expansion of the clavulanic acid gene cluster: identification and in vivo functional analysis of three new genes required for biosynthesis of clavulanic acid by Streptomyces clavuligerus. | Li R, Khaleeli N, Townsend CA. | J Bacteriol | 10.1128/jb.182.14.4087-4095.2000 | 2000 | | |
| Metabolism | Effect of protein binding on penetration of beta-lactams into rabbit peripheral lymph. | Woodnutt G, Berry V, Mizen L. | Antimicrob Agents Chemother | 10.1128/aac.39.12.2678 | 1995 | |
| Enzymology | Simulation of human serum pharmacokinetics of cefazolin, piperacillin, and BRL 42715 in rats and efficacy against experimental intraperitoneal infections. | Woodnutt G, Berry V, Mizen L. | Antimicrob Agents Chemother | 10.1128/aac.36.7.1427 | 1992 | |
| Metabolism | Deletion of the pyc gene blocks clavulanic acid biosynthesis except in glycerol-containing medium: evidence for two different genes in formation of the C3 unit. | Perez-Redondo R, Rodriguez-Garcia A, Martin JF, Liras P. | J Bacteriol | 10.1128/jb.181.22.6922-6928.1999 | 1999 | |
| Enzymology | Evaluation of piperacillin-tazobactam in experimental meningitis caused by a beta-lactamase-producing strain of K1-positive Escherichia coli. | Kern W, Kennedy SL, Sachdeva M, Sande ER, Gunderson D, Tauber MG. | Antimicrob Agents Chemother | 10.1128/aac.34.5.697 | 1990 | |
| Pathogenicity | BAL9141, a novel extended-spectrum cephalosporin active against methicillin-resistant Staphylococcus aureus in treatment of experimental endocarditis. | Entenza JM, Hohl P, Heinze-Krauss I, Glauser MP, Moreillon P. | Antimicrob Agents Chemother | 10.1128/aac.46.1.171-177.2002 | 2002 | |
| Comparative efficacies of ciprofloxacin, amoxicillin, amoxicillin-clavulanic acid, and cefaclor against experimental Streptococcus pneumoniae respiratory infections in mice. | Gisby J, Wightman BJ, Beale AS. | Antimicrob Agents Chemother | 10.1128/aac.35.5.831 | 1991 | | |
| Metabolism | beta-Lactam synthetase: a new biosynthetic enzyme. | Bachmann BO, Li R, Townsend CA. | Proc Natl Acad Sci U S A | 10.1073/pnas.95.16.9082 | 1998 | |
| Enzymology | Streptomyces clavuligerus has a second copy of the proclavaminate amidinohydrolase gene. | Jensen SE, Wong A, Griffin A, Barton B. | Antimicrob Agents Chemother | 10.1128/aac.48.2.514-520.2004 | 2004 | |
| Metabolism | Five additional genes are involved in clavulanic acid biosynthesis in Streptomyces clavuligerus. | Jensen SE, Paradkar AS, Mosher RH, Anders C, Beatty PH, Brumlik MJ, Griffin A, Barton B. | Antimicrob Agents Chemother | 10.1128/aac.48.1.192-202.2004 | 2004 | |
| Enzymology | Pharmacokinetic studies and renal dehydropeptidase stability of the new beta-lactamase inhibitor BRL 42715 in animals. | Coleman K, Griffin DR, Upshon PA. | Antimicrob Agents Chemother | 10.1128/aac.35.9.1748 | 1991 | |
| Metabolism | Pharmacokinetics of amoxicillin and clavulanic acid administered alone and in combination. | Adam D, de Visser I, Koeppe P. | Antimicrob Agents Chemother | 10.1128/aac.22.3.353 | 1982 | |
| Metabolism | Pharmacokinetics of ticarcillin and clavulanic acid (timentin) in relation to renal function. | Jungbluth GL, Cooper DL, Doyle GD, Chudzik GM, Jusko WJ. | Antimicrob Agents Chemother | 10.1128/aac.30.6.896 | 1986 | |
| Efficacy of ticarcillin-clavulanic acid for treatment of experimental Staphylococcus aureus endocarditis in rats. | Catherall EJ, Gillon V, Hurn S, Irwin R, Mizen L. | Antimicrob Agents Chemother | 10.1128/aac.36.2.458 | 1992 | | |
| Pathogenicity | Response of Streptococcus pyogenes to therapy with amoxicillin or amoxicillin-clavulanic acid in a mouse model of mixed infection caused by Staphylococcus aureus and Streptococcus pyogenes. | Boon RJ, Beale AS. | Antimicrob Agents Chemother | 10.1128/aac.31.8.1204 | 1987 | |
| Metabolism | Genes specific for the biosynthesis of clavam metabolites antipodal to clavulanic acid are clustered with the gene for clavaminate synthase 1 in Streptomyces clavuligerus. | Mosher RH, Paradkar AS, Anders C, Barton B, Jensen SE. | Antimicrob Agents Chemother | 10.1128/aac.43.5.1215 | 1999 | |
| Metabolism | Characterization of sugar uptake in wild-type Streptomyces clavuligerus, which is impaired in glucose uptake, and in a glucose-utilizing mutant. | Garcia-Dominguez M, Martin JF, Liras P. | J Bacteriol | 10.1128/jb.171.12.6808-6814.1989 | 1989 | |
| Enzymology | Purification to homogeneity and characterization of acyl coenzyme A:6-aminopenicillanic acid acyltransferase of Penicillium chrysogenum. | Alvarez E, Cantoral JM, Barredo JL, Diez B, Martin JF. | Antimicrob Agents Chemother | 10.1128/aac.31.11.1675 | 1987 | |
| Metabolism | Assay of amoxicillin and clavulanic acid, the components of Augmentin, in biological fluids with high-performance liquid chromatography. | Foulstone M, Reading C. | Antimicrob Agents Chemother | 10.1128/aac.22.5.753 | 1982 | |
| Pathogenicity | Synergistic Activity of Niclosamide in Combination With Colistin Against Colistin-Susceptible and Colistin-Resistant Acinetobacter baumannii and Klebsiella pneumoniae. | Ayerbe-Algaba R, Gil-Marques ML, Jimenez-Mejias ME, Sanchez-Encinales V, Parra-Millan R, Pachon-Ibanez ME, Pachon J, Smani Y. | Front Cell Infect Microbiol | 10.3389/fcimb.2018.00348 | 2018 | |
| Non-Antibiotic Drug Repositioning as an Alternative Antimicrobial Approach. | Barbarossa A, Rosato A, Corbo F, Clodoveo ML, Fracchiolla G, Carrieri A, Carocci A. | Antibiotics (Basel) | 10.3390/antibiotics11060816 | 2022 | | |
| Antibacterial Activity of Colloidal Silver against Gram-Negative and Gram-Positive Bacteria. | Vila Dominguez A, Ayerbe Algaba R, Miro Canturri A, Rodriguez Villodres A, Smani Y. | Antibiotics (Basel) | 10.3390/antibiotics9010036 | 2020 | | |
| Enzymology | Efficacies of colistin and tigecycline in mice with experimental pneumonia due to NDM-1-producing strains of Klebsiella pneumoniae and Escherichia coli. | Docobo-Perez F, Nordmann P, Dominguez-Herrera J, Lopez-Rojas R, Smani Y, Poirel L, Pachon J | Int J Antimicrob Agents | 10.1016/j.ijantimicag.2011.10.012 | 2011 | |
| Metabolism | The use of purine compounds as sole sources of carbon and nitrogen by Klebsiella species. | Wong SH | Microbios | 1988 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive139426.20260601.11
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
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