Klebsiella pneumoniae (DSM 25721, NCCP 13840)
Klebsiella pneumoniae DSM 25721 is a human pathogen that has multiple antibiotic resistances and was isolated from nasal aspirate.
antibiotic resistance human pathogen BacteriaName and taxonomic classification
| @ref 20215 |
Last LPSN update
2026-05-29 08:26:03 |
| Domain Bacteria |
| Phylum Pseudomonadota |
| Class Gammaproteobacteria |
| Order Enterobacterales |
| Family Enterobacteriaceae |
| Genus Klebsiella |
| Species Klebsiella pneumoniae |
| Full scientific name Klebsiella pneumoniae (Schroeter 1886) Trevisan 1887 (Approved Lists 1980) |
| Synonyms (1) |
Culture and growth conditions
Culture medium
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 18096 | TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) | Medium recipe at MediaDive  | Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water | ||
| 18096 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | Medium recipe at MediaDive | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base |
Culture temp
| @ref | Growth | Type | Temperature (°C) | |
|---|---|---|---|---|
| 18096 | positive | growth | 37 |
Physiology and metabolism
Antibiotic susceptibility testing
| Test 1 | Test 2 | Test 3 | |
|---|---|---|---|
| @ref | 18096 | 18096 | 18096 |
| Medium | Mueller-Hinton Agar | Mueller-Hinton Agar | Müller-Hinton Agar |
| Manual annotation | 1 | 1 | 1 |
| Inhibition zone diameter in mm | Inhibition zone diameter in mm | Inhibition zone diameter in mm | |
| Amikacin 30µg (disc) | 20 | 22 | 20 |
| Ampicillin 10µg (disc) | 0 | 0 | 0 |
| Aztreonam 30µg (disc) | 10 | 0 | 0 |
| Bacitracin 10Unit | 0 | 0 | n.d. |
| Cefalotin 30µg (disc) | 0 | 0 | n.d. |
| Cefazolin 30µg (disc) | 0 | 0 | n.d. |
| Cefiderocol 30µg (disc) | n.d. | n.d. | 28 |
| Cefotaxime 30µg (disc) | 6 | 0 | 0 |
| Ceftazidime 10µg (disc) | n.d. | n.d. | 6 |
| Ceftriaxone 30µg (disc) | 6 | 6 | 6 |
| Chloramphenicol 30µg (disc) | 8 | 0 | 0 |
| Ciprofloxacin 5µg (disc) | n.d. | n.d. | 10 |
| Clindamycin 10µg (disc) | 0 | 0 | 0 |
| Colistin 10µg (disc) | 14 | 12-14 | n.d. |
| Colistin sulphate 10µg (disc) | n.d. | n.d. | 16-18 |
| Doxycycline 30µg (disc) | 10 | 6-8 | n.d. |
| Erythromycin 15µg (disc) | 0 | 0 | 0 |
| Fosfomycin 50µg (disc) | 8 | 6-8 | 0 |
| Gentamicin 10µg (disc) | 10 | 8 | n.d. |
| Gentamicin 30µg (disc) | n.d. | n.d. | 10 |
| Imipenem 10µg (disc) | 28-30 | 30 | 30 |
| Kanamycin 30µg (disc) | 14 | 16 | 16 |
| Levofloxacin 5µg (disc) | n.d. | n.d. | 10 |
| Lincomycin 15µg (disc) | 0 | 0 | n.d. |
| Linezolid 10µg (disc) | 0 | 0 | 0 |
| Meropenem 10µg (disc) | n.d. | n.d. | 32 |
| Mezlocillin 30µg (disc) | 0 | 0 | n.d. |
| Moxifloxacin 5µg (disc) | 20 | 12 | 12 |
| Neomycin 30µg (disc) | 18 | 18 | n.d. |
| Nitrofurantoin 100µg (disc) | 16 | 10 | 8 |
| Norfloxacin 10µg (disc) | 16 | 0 | n.d. |
| Nystatin 100Unit | 0 | 0 | n.d. |
| Ofloxacin 5µg (disc) | 20 | 8 | 8-10 |
| Oxacillin 5µg (disc) | 0 | 0 | 0 |
| Penicillin G 6µg (disc) | 0 | 0 | 0 |
| Pipemidic acid 20µg (disc) | 12 | 0 | n.d. |
| Piperacillin/Tazobactam 40µg (disc) | 20 | 18 | n.d. |
| Piperacillin/Tazobactam 110µg (disc) | n.d. | n.d. | 20 |
| Polymyxin B 300Unit | 14-16 | 16 | 18 |
| Quinupristin/Dalfopristin 15µg (disc) | 0 | 0 | 0 |
| Rifampicin 5µg (disc) | n.d. | n.d. | 8 |
| Teicoplanin 30µg (disc) | 0 | 0 | 0 |
| Tetracycline 30µg (disc) | 6-8 | 0 | 0 |
| Ticarcillin 75µg (disc) | 0 | 0 | 0 |
| Tigecycline 15µg (disc) | n.d. | n.d. | 20 |
| Trimethoprim-sulfamethoxazole (1:19) 10µg (disc) | n.d. | n.d. | 8 |
| Vancomycin 30µg (disc) | 10 | 0 | 0 |
Compound production
| 18096 | Compoundextended spectrum ß-lactamase ESBL |
Observation
| 18096 | ObservationESBL |
Metabolite utilization
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68368 | 27613 ChEBI | amygdalin | + | fermentation | from API 20E |
| 68368 | 29016 ChEBI | arginine | - | hydrolysis | from API 20E |
| 68368 | 16947 ChEBI | citrate | + | assimilation | from API 20E |
| 68368 | 17634 ChEBI | D-glucose | + | fermentation | from API 20E |
| 68368 | 16899 ChEBI | D-mannitol | + | fermentation | from API 20E |
| 68368 | 5291 ChEBI | gelatin | - | hydrolysis | from API 20E |
| 68368 | 30849 ChEBI | L-arabinose | + | fermentation | from API 20E |
| 68368 | 62345 ChEBI | L-rhamnose | + | fermentation | from API 20E |
| 68368 | 25094 ChEBI | lysine | + | degradation | from API 20E |
| 68368 | 28053 ChEBI | melibiose | + | fermentation | from API 20E |
| 68368 | 17268 ChEBI | myo-inositol | + | fermentation | from API 20E |
| 68368 | 18257 ChEBI | ornithine | - | degradation | from API 20E |
| 68368 | 30911 ChEBI | sorbitol | + | fermentation | from API 20E |
| 68368 | 17992 ChEBI | sucrose | + | fermentation | from API 20E |
| 68368 | 27897 ChEBI | tryptophan | - | energy source | from API 20E |
| 68368 | 16199 ChEBI | urea | + | hydrolysis | from API 20E |
Antibiotic resistance
| @ref | ChEBI | Metabolite | Is resistant | Resistance conc. | |
|---|---|---|---|---|---|
| 18096 | 28971 | Ampicillin | 10 µg (disc) | from Antibiotic test | |
| 18096 | 28669 | Bacitracin | 10 Unit | from Antibiotic test | |
| 18096 | 124991 | Cefalotin | 30 µg (disc) | from Antibiotic test | |
| 18096 | 474053 | Cefazolin | 30 µg (disc) | from Antibiotic test | |
| 18096 | 3745 | Clindamycin | 10 µg (disc) | from Antibiotic test | |
| 18096 | 48923 | Erythromycin | 15 µg (disc) | from Antibiotic test | |
| 18096 | 6472 | Lincomycin | 15 µg (disc) | from Antibiotic test | |
| 18096 | 63607 | Linezolid | 10 µg (disc) | from Antibiotic test | |
| 18096 | 6919 | Mezlocillin | 30 µg (disc) | from Antibiotic test | |
| 18096 | 7660 | Nystatin | 100 Unit | from Antibiotic test | |
| 18096 | 7809 | Oxacillin | 5 µg (disc) | from Antibiotic test | |
| 18096 | 18208 | Penicillin G | 6 µg (disc) | from Antibiotic test | |
| 18096 | Quinupristin/Dalfopristin | 15 µg (disc) | from Antibiotic test | ||
| 18096 | 29687 | Teicoplanin | 30 µg (disc) | from Antibiotic test | |
| 18096 | 9587 | Ticarcillin | 75 µg (disc) | from Antibiotic test |
Metabolite production
Metabolite tests
Enzymes
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68368 | arginine dihydrolase | - | 3.5.3.6 | from API 20E |
| 68368 | beta-galactosidase | - | 3.2.1.23 | from API 20E |
| 68368 | cytochrome oxidase | - | 1.9.3.1 | from API 20E |
| 68368 | gelatinase | - | from API 20E | |
| 68368 | lysine decarboxylase | + | 4.1.1.18 | from API 20E |
| 68368 | ornithine decarboxylase | - | 4.1.1.17 | from API 20E |
| 68368 | tryptophan deaminase | - | 4.1.99.1 | from API 20E |
| 68368 | urease | + | 3.5.1.5 | from API 20E |
API 20E
| @ref | ONPG | ADH (Arg) | LDC (Lys) | ODC | CIT | H2S productionH2S | URE | TDA (Trp) | IND | Acetoin production (Voges Proskauer test)VP | GEL | GLU | MAN | INO | Sor | RHA | SAC | MEL | AMY | ARA | OX | Nitrite productionNO2 | Reduction to N2N2 | MotilityMOB | Growth on MacConkey mediumMAC | OF-O | OF-F | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 18096 | - | - | + | - | + | - | + | - | - | + | - | + | + | + | + | + | + | + | + | + | - | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. |
How to cite
If you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive4961.20260601.11
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain dataIsabel Schober, Julia Koblitz, Joaquim Sardà Carbasse, Christian Ebeling, Marvin Leon Schmidt, Adam Podstawka, Rohit Gupta, Vinodh Ilangovan, Javad Chamanara, Jörg Overmann, Lorenz Christian Reimer
Nucleic Acids Research; database issue 2025.
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