Klebsiella pneumoniae NCTC 13443 is an aerobe bacterium of the family Enterobacteriaceae.
aerobe genome sequence Bacteria| @ref 20215 |
Last LPSN update
2026-05-29 08:43:38 |
| Domain Bacteria |
| Phylum Pseudomonadota |
| Class Gammaproteobacteria |
| Order Enterobacterales |
| Family Enterobacteriaceae |
| Genus Klebsiella |
| Species Klebsiella pneumoniae |
| Full scientific name Klebsiella pneumoniae (Schroeter 1886) Trevisan 1887 (Approved Lists 1980) |
| Synonyms (1) |
| 63518 | Oxygen toleranceaerobe |
| @ref | Spore formation | Confidence | |
|---|---|---|---|
| 125439 | 96.07 |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68374 | 29016 ChEBI | arginine | - | hydrolysis | from API ID32E |
| 68374 | 17057 ChEBI | cellobiose | + | builds acid from | from API ID32E |
| 68374 | 18333 ChEBI | D-arabitol | + | builds acid from | from API ID32E |
| 68374 | 18024 ChEBI | D-galacturonic acid | + | builds acid from | from API ID32E |
| 68374 | 17634 ChEBI | D-glucose | + | builds acid from | from API ID32E |
| 68374 | 16899 ChEBI | D-mannitol | + | builds acid from | from API ID32E |
| 68374 | 30849 ChEBI | L-arabinose | + | builds acid from | from API ID32E |
| 68374 | 18403 ChEBI | L-arabitol | - | builds acid from | from API ID32E |
| 68374 | 62345 ChEBI | L-rhamnose | + | builds acid from | from API ID32E |
| 68374 | 25094 ChEBI | lysine | + | degradation | from API ID32E |
| 68374 | 15792 ChEBI | malonate | + | assimilation | from API ID32E |
| 68374 | 17306 ChEBI | maltose | + | builds acid from | from API ID32E |
| 68374 | 17268 ChEBI | myo-inositol | + | builds acid from | from API ID32E |
| 68374 | 18257 ChEBI | ornithine | - | degradation | from API ID32E |
| 68374 | 18394 ChEBI | palatinose | + | builds acid from | from API ID32E |
| 68374 | 0 ChEBI | Potassium 5-ketogluconate | - | builds acid from | from API ID32E |
| 68374 | 15963 ChEBI | ribitol | + | builds acid from | from API ID32E |
| 68374 | 30911 ChEBI | sorbitol | + | builds acid from | from API ID32E |
| 68374 | 17992 ChEBI | sucrose | + | builds acid from | from API ID32E |
| 68374 | 27082 ChEBI | trehalose | + | builds acid from | from API ID32E |
| 68374 | 27897 ChEBI | tryptophan | - | energy source | from API ID32E |
| 68374 | 16199 ChEBI | urea | + | hydrolysis | from API ID32E |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68374 | alpha-galactosidase | + | 3.2.1.22 | from API ID32E |
| 68374 | alpha-glucosidase | - | 3.2.1.20 | from API ID32E |
| 68374 | alpha-maltosidase | - | from API ID32E | |
| 68374 | arginine dihydrolase | - | 3.5.3.6 | from API ID32E |
| 68374 | beta-galactosidase | + | 3.2.1.23 | from API ID32E |
| 68374 | beta-glucosidase | + | 3.2.1.21 | from API ID32E |
| 68374 | beta-glucuronidase | - | 3.2.1.31 | from API ID32E |
| 68374 | L-aspartate arylamidase | + | 3.4.11.21 | from API ID32E |
| 68374 | lipase | - | from API ID32E | |
| 68374 | lysine decarboxylase | + | 4.1.1.18 | from API ID32E |
| 68374 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API ID32E |
| 68374 | ornithine decarboxylase | - | 4.1.1.17 | from API ID32E |
| 68374 | urease | + | 3.5.1.5 | from API ID32E |
| @ref | ODC | ADH (Arg) | LDC (Lys) | URE | LARL | GAT | 5KG | LipaseLIP | Phenol red (Acidification)RP | beta GLU | MAN | MAL | ADO | PLE | beta GUR | MNT | IND | N-Acetyl-beta-Glucosaminidasebeta NAG | beta GAL | GLU | SAC | LARA | DARL | alpha GLU | alpha GAL | TRE | RHA | INO | CEL | SOR | alpha-MaltosidasealphaMAL | L-aspartic acid arylamidaseAspA | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 63518 | - | - | + | + | - | + | - | - | - | + | + | + | + | + | - | + | - | - | + | + | + | + | + | - | + | + | + | + | + | + | - | + |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|
| 66792 | 32868_D02 assembly for Klebsiella pneumoniae NCTC13443 | contig | GCA_900451585   | 573.20120  | 573 | 19.87 | |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Development of disinfectant tolerance in Klebsiella pneumoniae. | Noel DJ, Keevil CW, Wilks SA. | J Hosp Infect | 10.1016/j.jhin.2024.11.006 | 2025 | | |
| Characterization of Carbapenem-Resistant Gram-Negative Bacilli Isolates in Multispecialty Private Hospitals in Lagos, Nigeria. | Salau M, Kositanont U, Noisumdaeng P, Ogunsola F, Ettu AO, Adewojo D, Ojimma C, Ojomaikre O, Changkaew K. | Infect Dis Rep | 10.3390/idr17050119 | 2025 | | |
| Convergent evolution of antibiotic resistance mechanisms between pyrrolobenzodiazepines and albicidin in multidrug resistant Klebsiella pneumoniae. | Surani YM, Wand ME, Picconi P, Di Palma M, Zenezini Chiozzi R, Hasan MM, Andriollo P, Gratz S, Nahar KS, Maynard-Smith M, Sussmuth RD, Steiner RA, Rahman KM, Hind CK, Sutton JM. | NPJ Antimicrob Resist | 10.1038/s44259-025-00104-4 | 2025 | | |
| LC-MS/MS metabolomics unravels the resistant phenotype of carbapenemase-producing Enterobacterales. | Dixon B, Ahmed WM, Fowler SJ, Felton T, Trivedi DK. | Metabolomics | 10.1007/s11306-025-02300-9 | 2025 | | |
| Laser-assisted microbial culturomics. | Qu T, Koch L, Mukherjee R, Tu Y, Seidel AL, Puttmann LD, Winkel A, Yang I, Grischke J, Liu D, Wolkers WF, Kittler S, Chichkov B, Stiesch M, Szafranski SP. | Nat Commun | 10.1038/s41467-025-66804-7 | 2025 | | |
| Comprehensive Genome Analysis of Colistin-Only-Sensitive KPC-2 and NDM1-1-Coproducing Klebsiella pneumoniae ST11 and Acinetobacter baumannii ST2 From a Critically Ill Patient With COVID-19 in Saudi Arabia: Whole Genome Sequencing (WGS) of K. pneumoniae ST11 and A. baumannii ST2. | Al-Zahrani IA, Brek TM. | Int J Microbiol | 10.1155/2024/9233075 | 2024 | | |
| Mutations in SilS and CusS/OmpC represent different routes to achieve high level silver ion tolerance in Klebsiella pneumoniae. | Woolley CA, Sutton JM, Wand ME. | BMC Microbiol | 10.1186/s12866-022-02532-y | 2022 | | |
| Resistance profiles of carbapenemase-producing Enterobacterales in a large centre in England: are we already losing cefiderocol? | Baltas I, Patel T, Soares AL. | J Antimicrob Chemother | 10.1093/jac/dkae367 | 2025 | | |
| Improving Turnaround Times for Routine Antimicrobial Sensitivity Testing Following European Committee on Antimicrobial Susceptibility Testing Methodology in Patients with Bacteraemia. | Edmondson R, Saeed K, Green S, O'Dwyer M. | Antibiotics (Basel) | 10.3390/antibiotics13111094 | 2024 | | |
| Phenotypic Ultra-Rapid Antimicrobial Susceptibility Testing for Ceftazidime-Avibactam: In Support of Antimicrobial Stewardship. | Martins-Oliveira I, Perez-Viso B, Gomes R, Abreu D, Silva-Dias A, Canton R, Pina-Vaz C. | Microorganisms | 10.3390/microorganisms13020414 | 2025 | | |
| Performance of Flow Cytometry-Based Rapid Assay in Detection of Carbapenemase-Producing Enterobacterales. | Perez-Viso B, Martins-Oliveira I, Gomes R, Silva-Dias A, Peixe L, Novais A, Pina-Vaz C, Canton R. | Int J Mol Sci | 10.3390/ijms25147888 | 2024 | | |
| In Vitro and In Vivo Activities of beta-Lactams in Combination with the Novel beta-Lactam Enhancers Zidebactam and WCK 5153 against Multidrug-Resistant Metallo-beta-Lactamase-Producing Klebsiella pneumoniae. | Moya B, Barcelo IM, Cabot G, Torrens G, Palwe S, Joshi P, Umarkar K, Takalkar S, Periasamy H, Bhagwat S, Patel M, Bou G, Oliver A. | Antimicrob Agents Chemother | 10.1128/aac.00128-19 | 2019 | | |
| Zidovudine enhances activity of carbapenems against NDM-1-producing Enterobacteriaceae. | Hu Y, Coates A. | J Antimicrob Chemother | 10.1093/jac/dkab184 | 2021 | | |
| Biofilm and Gene Expression Characteristics of the Carbapenem-Resistant Enterobacterales, Escherichia coli IMP, and Klebsiella pneumoniae NDM-1 Associated with Common Bacterial Infections. | Al-Bayati M, Samarasinghe S. | Int J Environ Res Public Health | 10.3390/ijerph19084788 | 2022 | | |
| Pathogenicity | Mechanisms of Increased Resistance to Chlorhexidine and Cross-Resistance to Colistin following Exposure of Klebsiella pneumoniae Clinical Isolates to Chlorhexidine. | Wand ME, Bock LJ, Bonney LC, Sutton JM. | Antimicrob Agents Chemother | 10.1128/aac.01162-16 | 2017 | |
| Peptidomimetic antibiotics disrupt the lipopolysaccharide transport bridge of drug-resistant Enterobacteriaceae. | Schuster M, Brabet E, Oi KK, Desjonqueres N, Moehle K, Le Poupon K, Hell S, Gable S, Rithie V, Dillinger S, Zbinden P, Luther A, Li C, Stiegeler S, D'Arco C, Locher H, Remus T, DiMaio S, Motta P, Wach A, Jung F, Upert G, Obrecht D, Benghezal M, Zerbe O. | Sci Adv | 10.1126/sciadv.adg3683 | 2023 | | |
| Potential cannabidiol (CBD) repurposing as antibacterial and promising therapy of CBD plus polymyxin B (PB) against PB-resistant gram-negative bacilli. | Abichabki N, Zacharias LV, Moreira NC, Bellissimo-Rodrigues F, Moreira FL, Benzi JRL, Ogasawara TMC, Ferreira JC, Ribeiro CM, Pavan FR, Pereira LRL, Brancini GTP, Braga GUL, Zuardi AW, Hallak JEC, Crippa JAS, Lanchote VL, Canton R, Darini ALC, Andrade LN. | Sci Rep | 10.1038/s41598-022-10393-8 | 2022 | | |
| SmvA is an important efflux pump for cationic biocides in Klebsiella pneumoniae and other Enterobacteriaceae. | Wand ME, Jamshidi S, Bock LJ, Rahman KM, Sutton JM. | Sci Rep | 10.1038/s41598-018-37730-0 | 2019 | | |
| Pathogenicity | The emergence of carbapenem-resistant Klebsiella pneumoniae isolates producing OXA-48 and NDM in the Southern (Asir) province, Saudi Arabia. | Al-Zahrani IA, Alsiri BA. | Saudi Med J | 10.15537/smj.2018.1.21094 | 2018 | |
| Evaluation of FASTinov Ultrarapid Flow Cytometry Antimicrobial Susceptibility Testing Directly from Positive Blood Cultures. | Silva-Dias A, Perez-Viso B, Martins-Oliveira I, Gomes R, Rodrigues AG, Canton R, Pina-Vaz C. | J Clin Microbiol | 10.1128/jcm.00544-21 | 2021 | | |
| Restoring carbapenem efficacy: a novel carbapenem companion targeting metallo-beta-lactamases in carbapenem-resistant Enterobacterales. | Ooi N, Lee VE, Chalam-Judge N, Newman R, Wilkinson AJ, Cooper IR, Orr D, Lee S, Savage VJ. | J Antimicrob Chemother | 10.1093/jac/dkaa455 | 2021 | | |
| Pathogenicity | In Vitro and In Vivo Characterization of NOSO-502, a Novel Inhibitor of Bacterial Translation. | Racine E, Nordmann P, Pantel L, Sarciaux M, Serri M, Houard J, Villain-Guillot P, Demords A, Vingsbo Lundberg C, Gualtieri M. | Antimicrob Agents Chemother | 10.1128/aac.01016-18 | 2018 | |
| Pathogenicity | Chicken cathelicidins display antimicrobial activity against multiresistant bacteria without inducing strong resistance. | Veldhuizen EJ, Brouwer EC, Schneider VA, Fluit AC. | PLoS One | 10.1371/journal.pone.0061964 | 2013 | |
| Enzymology | Rapid and simultaneous detection of genes encoding Klebsiella pneumoniae carbapenemase (blaKPC) and New Delhi metallo-beta-lactamase (blaNDM) in Gram-negative bacilli. | Cunningham SA, Noorie T, Meunier D, Woodford N, Patel R. | J Clin Microbiol | 10.1128/jcm.03062-12 | 2013 | |
| Enzymology | Rapid Detection of KPC, NDM, and OXA-48-Like Carbapenemases by Real-Time PCR from Rectal Swab Surveillance Samples. | Lee TD, Adie K, McNabb A, Purych D, Mannan K, Azana R, Ng C, Tang P, Hoang LM. | J Clin Microbiol | 10.1128/jcm.01237-15 | 2015 | |
| WCK 5222 (Cefepime/Zidebactam) Pharmacodynamic Target Analysis against Metallo-beta-lactamase producing Enterobacteriaceae in the Neutropenic Mouse Pneumonia Model. | Lepak AJ, Zhao M, Andes DR. | Antimicrob Agents Chemother | 10.1128/aac.01648-19 | 2019 | | |
| Enzymology | In Vivo Pharmacodynamic Study of Cefiderocol, a Novel Parenteral Siderophore Cephalosporin, in Murine Thigh and Lung Infection Models. | Nakamura R, Ito-Horiyama T, Takemura M, Toba S, Matsumoto S, Ikehara T, Tsuji M, Sato T, Yamano Y. | Antimicrob Agents Chemother | 10.1128/aac.02031-18 | 2019 | |
| Horizontal transfer of antibiotic resistance genes on abiotic touch surfaces: implications for public health. | Warnes SL, Highmore CJ, Keevil CW. | mBio | 10.1128/mbio.00489-12 | 2012 | | |
| Insights into the Resistome and Phylogenomics of a ST195 Multidrug-Resistant Acinetobacter baumannii Clinical Isolate from the Czech Republic. | Mlynarcik P, Dolejska M, Vagnerova I, Petrzelova J, Sukkar I, Zdarska V, Kolar M. | Life (Basel) | 10.3390/life11101079 | 2021 | | |
| Enzymology | Metallo-Beta-Lactamase-Producing Acinetobacter spp. from Clinical Isolates at a Tertiary Care Hospital in Ghana. | Olu-Taiwo MA, Opintan JA, Codjoe FS, Obeng Forson A. | Biomed Res Int | 10.1155/2020/3852419 | 2020 | |
| Pathogenicity | In Vitro Activities of Ceftazidime-Avibactam, Aztreonam-Avibactam, and a Panel of Older and Contemporary Antimicrobial Agents against Carbapenemase-Producing Gram-Negative Bacilli. | Vasoo S, Cunningham SA, Cole NC, Kohner PC, Menon SR, Krause KM, Harris KA, De PP, Koh TH, Patel R. | Antimicrob Agents Chemother | 10.1128/aac.02019-15 | 2015 | |
| Primer Evaluation for PCR and its Application for Detection of Carbapenemases in Enterobacteriaceae. | Mlynarcik P, Roderova M, Kolar M. | Jundishapur J Microbiol | 10.5812/jjm.29314 | 2016 | | |
| Enzymology | Development of two real-time multiplex PCR assays for the detection and quantification of eight key bacterial pathogens in lower respiratory tract infections. | Gadsby NJ, McHugh MP, Russell CD, Mark H, Conway Morris A, Laurenson IF, Hill AT, Templeton KE. | Clin Microbiol Infect | 10.1016/j.cmi.2015.05.004 | 2015 | |
| Enzymology | Rapid and direct real-time detection of blaKPC and blaNDM from surveillance samples. | Vasoo S, Cunningham SA, Kohner PC, Mandrekar JN, Lolans K, Hayden MK, Patel R. | J Clin Microbiol | 10.1128/jcm.01731-13 | 2013 | |
| Enzymology | Rapid and simultaneous detection of blaKPC and blaNDM by use of multiplex real-time PCR. | Milillo M, Kwak YI, Snesrud E, Waterman PE, Lesho E, McGann P. | J Clin Microbiol | 10.1128/jcm.03316-12 | 2013 | |
| Pathogenicity | Whole-genome sequencing of a large collection of Myroides odoratimimus and Myroides odoratus isolates and antimicrobial susceptibility studies. | Gunzer F, Rudolph WW, Bunk B, Schober I, Peters S, Muller T, Oberheitmann B, Schrottner P. | Emerg Microbes Infect | 10.1038/s41426-018-0061-x | 2018 | |
| Pathogenicity | Antimicrobial Peptide Novicidin Synergizes with Rifampin, Ceftriaxone, and Ceftazidime against Antibiotic-Resistant Enterobacteriaceae In Vitro. | Soren O, Brinch KS, Patel D, Liu Y, Liu A, Coates A, Hu Y. | Antimicrob Agents Chemother | 10.1128/aac.01245-15 | 2015 | |
| Enzymology | Detection of colonization by carbapenemase-producing Gram-negative Bacilli in patients by use of the Xpert MDRO assay. | Tenover FC, Canton R, Kop J, Chan R, Ryan J, Weir F, Ruiz-Garbajosa P, LaBombardi V, Persing DH. | J Clin Microbiol | 10.1128/jcm.01092-13 | 2013 | |
| Complete sequence of a novel 178-kilobase plasmid carrying bla(NDM-1) in a Providencia stuartii strain isolated in Afghanistan. | McGann P, Hang J, Clifford RJ, Yang Y, Kwak YI, Kuschner RA, Lesho EP, Waterman PE. | Antimicrob Agents Chemother | 10.1128/aac.05604-11 | 2012 | | |
| Pathogenicity | Synergism versus Additivity: Defining the Interactions between Common Disinfectants. | Noel DJ, Keevil CW, Wilks SA | mBio | 10.1128/mBio.02281-21 | 2021 | |
| Pathogenicity | Simple and rapid sample preparation system for the molecular detection of antibiotic resistant pathogens in human urine. | Valiadi M, Kalsi S, Jones IG, Turner C, Sutton JM, Morgan H | Biomed Microdevices | 10.1007/s10544-016-0031-9 | 2016 | |
| Pathogenicity | Real-time PCR assay allows detection of the New Delhi metallo-beta-lactamase (NDM-1)-encoding gene in France. | Diene SM, Bruder N, Raoult D, Rolain JM | Int J Antimicrob Agents | 10.1016/j.ijantimicag.2011.02.006 | 2011 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive157026.20260601.11
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
License