Streptomyces albidoflavus (DSM 40233, ATCC 23899, CBS 210.27)

Cell morphology

Multimedia

• @ref:	9394
  multimedia content:	DSM_40233.jpg
  multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_40233.jpg
  caption:	Medium 65 28°C
  intellectual property rights:	© Leibniz-Institut DSMZ
  manual_annotation:	1

Culture medium

@ref	Name	Growth	Medium link	Composition
9394	GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)		Medium recipe at MediaDive	Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water
9394	ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84)		Medium recipe at MediaDive	Name: ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84) Composition: Agar 20.0 g/l Rolled oats 20.0 g/l ZnSO4 x 7 H2O 0.001 g/l MnCl2 x 4 H2O 0.001 g/l FeSO4 x 7 H2O 0.001 g/l Distilled water

Culture temp

Oxygen tolerance

Spore formation

Compound production

Halophily

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
18565	22599 ChEBI	arabinose	+
68368	29016 ChEBI	arginine	-	hydrolysis	from API 20E
18565	62968 ChEBI	cellulose	-
68368	16947 ChEBI	citrate	+	assimilation	from API 20E
18565	28757 ChEBI	fructose	+
68368	5291 ChEBI	gelatin	+	hydrolysis	from API 20E
18565	17234 ChEBI	glucose	+
68368	25094 ChEBI	lysine	-	degradation	from API 20E
18565	29864 ChEBI	mannitol	+
18565	17268 ChEBI	myo-inositol	-
68368	18257 ChEBI	ornithine	-	degradation	from API 20E
18565	16634 ChEBI	raffinose	-
18565	26546 ChEBI	rhamnose	-
18565	17992 ChEBI	sucrose	-
68368	27897 ChEBI	tryptophan	-	energy source	from API 20E
68368	16199 ChEBI	urea	-	hydrolysis	from API 20E
18565	18222 ChEBI	xylose	+/-

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68368	15688 ChEBI	acetoin		from API 20E
68368	16136 ChEBI	hydrogen sulfide		from API 20E
68368	35581 ChEBI	indole		from API 20E

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Indole test
68368	15688 ChEBI	acetoin	-		from API 20E
68368	35581 ChEBI	indole		-	from API 20E

Enzymes

@ref	Value	Activity	Ec
68368	arginine dihydrolase	-	3.5.3.6	from API 20E
68368	beta-galactosidase	-	3.2.1.23	from API 20E
68368	gelatinase	+		from API 20E
68368	lysine decarboxylase	-	4.1.1.18	from API 20E
68368	ornithine decarboxylase	-	4.1.1.17	from API 20E
68368	tryptophan deaminase	-	4.1.99.1	from API 20E
68368	urease	-	3.5.1.5	from API 20E

API 20E

Taxonmaps

69479

Global distribution of 16S sequence Z76678 (>99% sequence identity) for Streptomyces from Microbeatlas

Aquatic Samples	5
Soil Samples	39
Animal Samples	85
Plant Samples
Total Samples	129

Risk assessment

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	NCBI tax ID	Score
124043	ASM3447904v1 assembly for Streptomyces albidoflavus ATCC 23899	complete	GCA_034479045	1886.219	1886	98.86
66792	ASM2052131v1 assembly for Streptomyces albidoflavus NBRC 12854	contig	GCA_020521315	1886.102	1886	76.65
66792	Streptomyces albidoflavus strain NBRC 12854	contig		1886.115	1886	76.4
66792	Streptomyces albidoflavus strain NBRC 12854	contig		1886.114	1886	76.4
67770	ASM419577v1 assembly for Streptomyces albidoflavus DSM 40233	contig	GCA_004195775	1886.40	1886	65.26

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20218	Streptomyces coelicolor strain DSM40233 16S-23S intergenic spacer region, partial sequence	AF363491	304		1902
20218	Streptomyces coelicolor gene for 16S ribosomal RNA, partial sequence, strain: JCM 4357	D44075	120		1902
20218	Streptomyces coelicolor strain DSM 40233 16S ribosomal RNA gene, partial sequence	FJ406047	1396		1902
20218	Streptomyces coelicolor strain DSM 40233 16S ribosomal RNA gene, partial sequence	GU383131	781		1902
20218	S.coelicolor (DSM 40233T) 16S rRNA gene	Z76678	1476		1902
9394	Streptomyces coelicolor gene for 16S rRNA, partial sequence, strain: NBRC 12854	AB184196	1476		1902
124043	Streptomyces coelicolor strain DSM 40233 16S ribosomal RNA gene, partial sequence.	KY820697	1008		1902
124043	Streptomyces coelicolor strain DSM 40233 16S ribosomal RNA gene, partial sequence.	KY820720	1037		1902
124043	Streptomyces coelicolor strain DSM 40233 16S ribosomal RNA gene, partial sequence.	KY820661	1048		1902
124043	Streptomyces coelicolor strain DSM 40233 16S ribosomal RNA gene, partial sequence.	KY820662	1094		1902
124043	Streptomyces coelicolor strain DSM 40233 16S ribosomal RNA gene, partial sequence.	KY820719	993		1902
124043	Streptomyces coelicolor strain DSM 40233 16S ribosomal RNA gene, partial sequence.	KY820660	1094		1902

GC content

Predictions

Literature

Topic	Title	Authors	Journal	DOI	Year
	Genomic Insights into the Microbial Agent Streptomyces albidoflavus MGMM6 for Various Biotechnology Applications.	Diabankana RGC, Frolov M, Keremli S, Validov SZ, Afordoanyi DM.	Microorganisms	10.3390/microorganisms11122872	2023
Genetics	Population Genomics Insights into Adaptive Evolution and Ecological Differentiation in Streptomycetes.	Li Y, Pinto-Tomas AA, Rong X, Cheng K, Liu M, Huang Y.	Appl Environ Microbiol	10.1128/aem.02555-18	2019
	Population genetic analysis of Streptomyces albidoflavus reveals habitat barriers to homologous recombination in the diversification of streptomycetes.	Cheng K, Rong X, Pinto-Tomas AA, Fernandez-Villalobos M, Murillo-Cruz C, Huang Y.	Appl Environ Microbiol	10.1128/aem.02925-14	2015
Pathogenicity	Isolation and characterization of the new Streptomyces phages Kamino, Geonosis, Abafar, and Scarif infecting a broad range of host species.	Rackow B, Rolland C, Mohnen I, Wittmann J, Musken M, Overmann J, Frunzke J.	Microbiol Spectr	10.1128/spectrum.00663-24	2024
	Biosynthesis of Hesperetin, Homoeriodictyol, and Homohesperetin in a Transcriptomics-Driven Engineered Strain of Streptomyces albidoflavus.	Perez-Valero A, Serna-Diestro J, Tafur Rangel A, Barbuto Ferraiuolo S, Schiraldi C, Kerkhoven EJ, Villar CJ, Lombo F.	Int J Mol Sci	10.3390/ijms25074053	2024
Pathogenicity	Activation of paulomycin production by exogenous gamma-butyrolactone signaling molecules in Streptomyces albidoflavus J1074.	Zhang Y, Wang M, Tian J, Liu J, Guo Z, Tang W, Chen Y.	Appl Microbiol Biotechnol	10.1007/s00253-019-10329-9	2020
Biotechnology	Actinomycete-Derived Pigments: A Path Toward Sustainable Industrial Colorants.	Diez BH, Torres CAV, Gaudencio SP.	Mar Drugs	10.3390/md23010039	2025
Metabolism	Candicidin Isomer Production Is Essential for Biocontrol of Cucumber Rhizoctonia Rot by Streptomyces albidoflavus W68.	Yao X, Zhang Z, Huang J, Wei S, Sun X, Chen Y, Liu H, Li S.	Appl Environ Microbiol	10.1128/aem.03078-20	2021
	Morphology-engineered alleviation of mycelial aggregation in Streptomyces chassis for potentiated production of secondary metabolites.	Liu S, Xiao F, Lv L, Wang M, Li W, Niu G.	Synth Syst Biotechnol	10.1016/j.synbio.2025.05.010	2025
	2-Amino-3-Chlorobenzoic Acid from Streptomyces coelicolor: A Cancer Antagonist Targeting PI3K/AKT Markers via miRNA Modulation.	Khalifa A, Balthazar JD, Subash-Babu P, Zaky MY, El-Moaty ZA, M Ibrahim HI.	Pharmaceuticals (Basel)	10.3390/ph18050620	2025
	A Pressure Test to Make 10 Molecules in 90 Days: External Evaluation of Methods to Engineer Biology.	Casini A, Chang FY, Eluere R, King AM, Young EM, Dudley QM, Karim A, Pratt K, Bristol C, Forget A, Ghodasara A, Warden-Rothman R, Gan R, Cristofaro A, Borujeni AE, Ryu MH, Li J, Kwon YC, Wang H, Tatsis E, Rodriguez-Lopez C, O'Connor S, Medema MH, Fischbach MA, Jewett MC, Voigt C, Gordon DB.	J Am Chem Soc	10.1021/jacs.7b13292	2018
Phylogeny	The newest Oxford Nanopore R10.4.1 full-length 16S rRNA sequencing enables the accurate resolution of species-level microbial community profiling.	Zhang T, Li H, Ma S, Cao J, Liao H, Huang Q, Chen W.	Appl Environ Microbiol	10.1128/aem.00605-23	2023
	A Multidisciplinary Approach to Unraveling the Natural Product Biosynthetic Potential of a Streptomyces Strain Collection Isolated from Leaf-Cutting Ants.	Ceniceros A, Cuervo L, Mendez C, Salas JA, Olano C, Malmierca MG.	Microorganisms	10.3390/microorganisms9112225	2021
	High-Throughput Transcriptional Characterization of Regulatory Sequences from Bacterial Biosynthetic Gene Clusters.	Park J, Yim SS, Wang HH.	ACS Synth Biol	10.1021/acssynbio.0c00639	2021
	Discovery and characterisation of an amidine-containing ribosomally-synthesised peptide that is widely distributed in nature.	Russell AH, Vior NM, Hems ES, Lacret R, Truman AW.	Chem Sci	10.1039/d1sc01456k	2021
	Identification of novel tail-anchored membrane proteins integrated by the bacterial twin-arginine translocase.	Gallego-Parrilla JJ, Severi E, Chandra G, Palmer T.	Microbiology (Reading)	10.1099/mic.0.001431	2024
	Exploring a general multi-pronged activation strategy for natural product discovery in Actinomycetes.	Tay DWP, Tan LL, Heng E, Zulkarnain N, Ching KC, Wibowo M, Chin EJ, Tan ZYQ, Leong CY, Ng VWP, Yang LK, Seow DCS, Lim YW, Koh W, Koduru L, Kanagasundaram Y, Ng SB, Lim YH, Wong FT.	Commun Biol	10.1038/s42003-023-05648-7	2024
	An unusual aromatase/cyclase programs the formation of the phenyldimethylanthrone framework in anthrabenzoxocinones and fasamycin.	Jiang K, Chen X, Yan X, Li G, Lin Z, Deng Z, Luo S, Qu X.	Proc Natl Acad Sci U S A	10.1073/pnas.2321722121	2024
	Cost-effective hybrid long-short read assembly delineates alternative GC-rich Streptomyces hosts for natural product discovery.	Heng E, Tan LL, Tay DWP, Lim YH, Yang LK, Seow DCS, Leong CY, Ng V, Ng SB, Kanagasundaram Y, Wong FT, Koduru L.	Synth Syst Biotechnol	10.1016/j.synbio.2023.03.001	2023
	Exploring the Potential of Halotolerant Actinomycetes from Rann of Kutch, India: A Study on the Synthesis, Characterization, and Biomedical Applications of Silver Nanoparticles.	Dayma P, Choudhary N, Ali D, Alarifi S, Dudhagara P, Luhana K, Yadav VK, Patel A, Patel R.	Pharmaceuticals (Basel)	10.3390/ph17060743	2024
Genetics	Pangenome analysis of Corynebacterium striatum: insights into a neglected multidrug-resistant pathogen.	Nageeb WM, Hetta HF.	BMC Microbiol	10.1186/s12866-023-02996-6	2023
Biotechnology	An Efficient Markerless Deletion System Suitable for the Industrial Strains of Streptomyces.	Dong J, Wei J, Li H, Zhao S, Guan W.	J Microbiol Biotechnol	10.4014/jmb.2106.06083	2021
	A rational multi-target combination strategy for synergistic improvement of non-ribosomal peptide production.	Yan H, Xin Z, Sang Z, Li X, Xie J, Wu J, Pang S, Wen Y, Wang W.	Nat Commun	10.1038/s41467-025-57073-5	2025
	Atmospheric Precipitations, Hailstone and Rainwater, as a Novel Source of Streptomyces Producing Bioactive Natural Products.	Sarmiento-Vizcaino A, Espadas J, Martin J, Brana AF, Reyes F, Garcia LA, Blanco G.	Front Microbiol	10.3389/fmicb.2018.00773	2018
	Genetic approaches to improve clorobiocin production in Streptomyces roseochromogenes NRRL 3504.	Melnyk S, Stepanyshyn A, Yushchuk O, Mandler M, Ostash I, Koshla O, Fedorenko V, Kahne D, Ostash B.	Appl Microbiol Biotechnol	10.1007/s00253-022-11814-4	2022
Genetics	The Genome Analysis of the Human Lung-Associated Streptomyces sp. TR1341 Revealed the Presence of Beneficial Genes for Opportunistic Colonization of Human Tissues.	Lara AC, Corretto E, Kotrbova L, Lorenc F, Petrickova K, Grabic R, Chronakova A.	Microorganisms	10.3390/microorganisms9081547	2021
	Discovery, Yield Improvement, and Application in Marine Coatings of Potent Antifouling Compounds Albofungins Targeting Multiple Fouling Organisms.	She W, Ye W, Cheng A, Ye W, Ma C, Wang R, Cheng J, Liu X, Yuan Y, Chik SY, Limlingan Malit JJ, Lu Y, Chen F, Qian PY.	Front Microbiol	10.3389/fmicb.2022.906345	2022
Genetics	Bioactive Metabolites from Terrestrial and Marine Actinomycetes.	Ngamcharungchit C, Chaimusik N, Panbangred W, Euanorasetr J, Intra B.	Molecules	10.3390/molecules28155915	2023
	Versioning biological cells for trustworthy cell engineering.	Tellechea-Luzardo J, Hobbs L, Velazquez E, Pelechova L, Woods S, de Lorenzo V, Krasnogor N.	Nat Commun	10.1038/s41467-022-28350-4	2022
Pathogenicity	Streptomyces Endophytes Promote Host Health and Enhance Growth across Plant Species.	Worsley SF, Newitt J, Rassbach J, Batey SFD, Holmes NA, Murrell JC, Wilkinson B, Hutchings MI.	Appl Environ Microbiol	10.1128/aem.01053-20	2020
	Regulation of Antibiotic Production by Signaling Molecules in Streptomyces.	Kong D, Wang X, Nie J, Niu G.	Front Microbiol	10.3389/fmicb.2019.02927	2019
Genetics	Comparative genomics reveals broad genetic diversity, extensive recombination and nascent ecological adaptation in Micrococcus luteus.	Li Y, Sun ZZ, Rong JC, Xie BB.	BMC Genomics	10.1186/s12864-021-07432-5	2021
	Bilateral symmetry of linear streptomycete chromosomes.	Algora-Gallardo L, Schniete JK, Mark DR, Hunter IS, Herron PR.	Microb Genom	10.1099/mgen.0.000692	2021
Phylogeny	Phylogenetic relationships in the family Streptomycetaceae using multi-locus sequence analysis.	Labeda DP, Dunlap CA, Rong X, Huang Y, Doroghazi JR, Ju KS, Metcalf WW.	Antonie Van Leeuwenhoek	10.1007/s10482-016-0824-0	2017
Phylogeny	Discrimination of Streptomyces albidoflavus strains based on the size and number of 16S-23S ribosomal DNA intergenic spacers.	Hain T, Ward-Rainey N, Kroppenstedt RM, Stackebrandt E, Rainey FA.	Int J Syst Bacteriol	10.1099/00207713-47-1-202	1997
Metabolism	Dissolution of the Disparate: Co-ordinate Regulation in Antibiotic Biosynthesis.	McLean TC, Wilkinson B, Hutchings MI, Devine R.	Antibiotics (Basel)	10.3390/antibiotics8020083	2019
Metabolism	Enhanced Triacylglycerol Metabolism Contributes to Efficient Oil Utilization and High-Level Production of Salinomycin in Streptomyces albus ZD11.	Li H, Wei J, Dong J, Li Y, Li Y, Chen Y, Guan W.	Appl Environ Microbiol	10.1128/aem.00763-20	2020
	Advances in actinomycete research: an ActinoBase review of 2019.	Prudence SMM, Addington E, Castano-Espriu L, Mark DR, Pintor-Escobar L, Russell AH, McLean TC.	Microbiology (Reading)	10.1099/mic.0.000944	2020
	Bacterial terpenome.	Rudolf JD, Alsup TA, Xu B, Li Z.	Nat Prod Rep	10.1039/d0np00066c	2021
	Bioprospecting Sponge-Associated Microbes for Antimicrobial Compounds.	Indraningrat AA, Smidt H, Sipkema D.	Mar Drugs	10.3390/md14050087	2016
Phylogeny	A sensitive pH indicator-based spectrophotometric assay for PHB depolymerase activity on microtiter plates.	Camacho-Ruiz MA, Muller-Santos M, Hernandez-Mancillas XD, Armenta-Perez VP, Zamora-Gonzalez E, Rodriguez JA	Anal Methods	10.1039/d0ay00840k	2020