Lactobacillus crispatus (CIP 104459, 58-098-135)

Name: Lactobacillus crispatus (CIP 104459, 58-098-135)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 137068

Type strain

Strain Designation 58-098-135

Culture col. no. CIP 104459 58-098-135

NCBI tax ID(s) 47770

Special Collections CIP

History CIP <- 1995, F. Gasser, Inst. Pasteur, Paris, France: strain 63Fa, Lactobacillus acidophilus <- F. Guillermet, Inst. Pasteur, Lyon, France: strain 58-098-135 <- Croix-Rousse Hosp., Lyon, France

Links

Lactobacillus crispatus 58-098-135 is a facultative anaerobe, mesophilic, Gram-positive prokaryote of the family Lactobacillaceae.

Gram-positive rod-shaped facultative anaerobe mesophilic genome sequence 16S sequence

Name and taxonomic classification

SI-ID 68990

CIP 104459

@ref 20215

Last LPSN update 2026-02-09 11:32:48

Domain Bacteria

Phylum Bacillota

Class Bacilli

Order Lactobacillales

Family Lactobacillaceae

Genus Lactobacillus

Species Lactobacillus crispatus

Full scientific name Lactobacillus crispatus (Brygoo and Aladame 1953) Moore and Holdeman 1970 (Approved Lists 1980)

Synonyms (1)

"Eubacterium crispatum"

BacDive ID	Other strains from **Lactobacillus crispatus** (34)	Type strain
6442	L. crispatus DSM 20584, ATCC 33820, CCUG 30722, JCM 1185, ... (type strain)
6441	L. crispatus A 12, DSM 20356, JCM 2123, CIP 105000, LMG ...
135308	L. crispatus CIP 103602, CG 97, VPI 1784
135309	L. crispatus CIP 103603, NCTC 4505, NCIMB 4505, CCUG 42897, ...
135310	L. crispatus VJ-A, CIP 103604, VPI 6317
135311	L. crispatus CIP 103605, VPI 7635
135475	L. crispatus F3, CIP 105003, JCM 8780, LMG 18201
136226	L. crispatus A11, CIP 103608
138142	L. crispatus F5, CIP 105004, JCM 8781, CCUG 31411, LMG ...
138805	L. crispatus A5, CIP 103606, VPI 11697
139286	L. crispatus Sp34, CIP 105001, JCM 5808, KCTC 3176, LMG ...
139287	L. crispatus CIP 105002, JCM 5810, KCTC 3178, LMG 18191
144917	L. crispatus CCUG 27076 A
145367	L. crispatus CCUG 28280
146793	L. crispatus CCUG 32128
148293	L. crispatus CCUG 35170
149929	L. crispatus CCUG 38700
150970	L. crispatus CCUG 42898, NCIMB 4504, NCTC 4504, LMG 12005
151041	L. crispatus CCUG 43131
151380	L. crispatus CCUG 44015
151479	L. crispatus CCUG 44128
152257	L. crispatus CCUG 46228
152773	L. crispatus CCUG 47593
155480	L. crispatus CCUG 57836
160075	L. crispatus Cla-CZ-47, DSM 108970
160903	L. crispatus JCM 1030, KCTC 3147, LMG 12003, NCFB 2172, ...
162742	L. crispatus JCM 2009, ATCC 33197, LMG 12004, VPI 7635
165301	L. crispatus JCM 5806, KCTC 3174, LMG 18187
165564	L. crispatus JCM 7696
165565	L. crispatus JCM 7697
165568	L. crispatus JCM 7702
165950	L. crispatus JCM 8778, LMG 18199
165951	L. crispatus JCM 8779, LMG 18200
172658	L. crispatus 2082, CRBIP24.77

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Confidence
125438			93.5
125438	positive		94.193
36916	positive	rod-shaped

Culture and growth conditions

Culture medium

@ref	Name	Growth	Composition	Medium link
36916	MEDIUM 40- for Lactobacillus and Leuconostoc		Distilled water make up to (1000.000 ml);Man Rogosa Sharp agar (68.000 g)
36916	CIP Medium 40			Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
36916	positive	growth	37	mesophilic
36916	negative	growth	15
36916	negative	growth	45

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
36916	facultative anaerobe
125439	obligate aerobe	98.8

Spore formation

@ref	Spore formation	Confidence
125438		91.438

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68371	18305 ChEBI	arbutin	+	builds acid from	from API 50CH acid
68371	17057 ChEBI	cellobiose	+	builds acid from	from API 50CH acid
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68371	15824 ChEBI	D-fructose	+	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	+	builds acid from	from API 50CH acid
68371	17634 ChEBI	D-glucose	+	builds acid from	from API 50CH acid
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68371	16899 ChEBI	D-mannitol	-	builds acid from	from API 50CH acid
68371	16024 ChEBI	D-mannose	+	builds acid from	from API 50CH acid
68371	16988 ChEBI	D-ribose	-	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68371	16443 ChEBI	D-tagatose	-	builds acid from	from API 50CH acid
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
68371	4853 ChEBI	esculin	+	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	-	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
68371	28087 ChEBI	glycogen	+	builds acid from	from API 50CH acid
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68371	30849 ChEBI	L-arabinose	-	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68371	17716 ChEBI	lactose	+	builds acid from	from API 50CH acid
68371	17306 ChEBI	maltose	+	builds acid from	from API 50CH acid
68371	6731 ChEBI	melezitose	-	builds acid from	from API 50CH acid
68371	28053 ChEBI	melibiose	-	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
68371	59640 ChEBI	N-acetylglucosamine	+	builds acid from	from API 50CH acid
36916	17632 ChEBI	nitrate	-	reduction
36916	17632 ChEBI	nitrate	+	respiration
36916	16301 ChEBI	nitrite	-	reduction
68371		Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371		Potassium 5-ketogluconate	-	builds acid from	from API 50CH acid
68371	16634 ChEBI	raffinose	-	builds acid from	from API 50CH acid
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
68371	17814 ChEBI	salicin	+	builds acid from	from API 50CH acid
68371	28017 ChEBI	starch	+	builds acid from	from API 50CH acid
68371	17992 ChEBI	sucrose	+	builds acid from	from API 50CH acid
68371	27082 ChEBI	trehalose	+	builds acid from	from API 50CH acid
68371	32528 ChEBI	turanose	-	builds acid from	from API 50CH acid
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test
36916	15688 ChEBI	acetoin	-

Enzymes

@ref	Value	Activity	Ec
36916	alcohol dehydrogenase	-	1.1.1.1
36916	catalase	-	1.11.1.6
36916	lysine decarboxylase	-	4.1.1.18
36916	ornithine decarboxylase	-	4.1.1.17
36916	oxidase	-

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
36916	not determinedn.d.	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	-	-	-	-	+	+/-	+	+	+	+	+	+	-	+	+	-	-	-	+	+	-	+/-	-	-	-	-	-	-	-	-	-	-

Isolation, sampling and environmental information

Isolation

@ref	Sample type	Geographic location	Country	Country ISO 3 Code	Continent	Isolation date
36916		Lyon	France	FRA	Europe
36916	Human, Vaginal swab	Lyon	France	FRA	Europe	1955

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
36916	1	Risk group (French classification)

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	NCBI tax ID	Score
66792	ASM807931v1 assembly for Lactobacillus crispatus CIP 104459	contig	GCA_008079315	47770.572	47770	48.78

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
124043	Lactobacillus crispatus strain CIP 104459 16S ribosomal RNA gene, partial sequence.	MN744551	1560		47770

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Lactobacillus crispatus CIP 104459
NCBI: GCA_008079315

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	yes	60.40	no
125439	motility	BacteriaNetⓘ	yes	56.00	no
125439	gram_stain	BacteriaNetⓘ	positive	73.90	no
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	98.80	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Lactobacillus crispatus strain CIP 104459
PATRIC: 47770.572

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	94.19	no
125438	anaerobic	anaerobicⓘ	no	69.03	no
125438	spore-forming	spore-formingⓘ	no	91.44	no
125438	aerobic	aerobicⓘ	no	97.64	yes
125438	thermophilic	thermophileⓘ	no	95.50	no
125438	flagellated	motile2+ⓘ	no	93.50	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Genetics	Characterization of the first vaginal Lactobacillus crispatus genomes isolated in Brazil.	Oliveira de Almeida M, Carvalho R, Figueira Aburjaile F, Malcher Miranda F, Canario Cerqueira J, Brenig B, Ghosh P, Ramos R, Kato RB, de Castro Soares S, Silva A, Azevedo V, Canario Viana MV.	PeerJ	10.7717/peerj.11079	2021
	Effect of 17beta-estradiol on a human vaginal Lactobacillus crispatus strain.	Clabaut M, Suet A, Racine PJ, Tahrioui A, Verdon J, Barreau M, Maillot O, Le Tirant A, Karsybayeva M, Kremser C, Redziniak G, Duclairoir-Poc C, Pichon C, Chevalier S, Feuilloley MGJ.	Sci Rep	10.1038/s41598-021-86628-x	2021
Pathogenicity	Variability of the response of human vaginal Lactobacillus crispatus to 17beta-estradiol.	Clabaut M, Boukerb AM, Mlouka AB, Suet A, Tahrioui A, Verdon J, Barreau M, Maillot O, Le Tirant A, Karsybayeva M, Kremser C, Redziniak G, Duclairoir-Poc C, Pichon C, Hardouin J, Cosette P, Chevalier S, Feuilloley MGJ	Sci Rep	10.1038/s41598-021-91017-5	2021
Genetics	Draft Genome Sequence of Lactobacillus crispatus CIP 104459, Isolated from a Vaginal Swab.	Clabaut M, Boukerb AM, Racine PJ, Pichon C, Kremser C, Picot JP, Karsybayeva M, Redziniak G, Chevalier S, Feuilloley MGJ	Microbiol Resour Announc	10.1128/MRA.01373-19	2020

References

#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#36916	Collection of Institut Pasteur ; Curators of the CIP; CIP 104459
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#68371	Automatically annotated from API 50CH acid .
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Lactobacillus crispatus (CIP 104459, 58-098-135)

Name and taxonomic classification

Morphology

Cell morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Metabolite utilization

Metabolite tests

Enzymes

API 50CHac

Isolation, sampling and environmental information

Isolation

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_008079315

16S sequences

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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