Acinetobacter baumannii 7788 is an obligate aerobe, mesophilic, Gram-negative prokaryote that was isolated from Blood culture.
Gram-negative rod-shaped obligate aerobe mesophilic genome sequence| @ref 20215 |
Last LPSN update
2025-12-16 10:03:06 |
| Domain Pseudomonadati |
| Phylum Pseudomonadota |
| Class Gammaproteobacteria |
| Order Pseudomonadales |
| Family Moraxellaceae |
| Genus Acinetobacter |
| Species Acinetobacter baumannii |
| Full scientific name Acinetobacter baumannii Bouvet and Grimont 1986 |
| @ref | Spore formation | Confidence | |
|---|---|---|---|
| 125438 | 93.027 |
| @ref | Metabolite | Is antibiotic | Is sensitive | Is resistant | |
|---|---|---|---|---|---|
| 40088 | 0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate) |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 68382 | alkaline phosphatase | + | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | - | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 40088 | beta-galactosidase | - | 3.2.1.23 | |
| 68382 | beta-glucosidase | - | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 40088 | catalase | + | 1.11.1.6 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 68382 | esterase (C 4) | + | from API zym | |
| 68382 | esterase lipase (C 8) | + | from API zym | |
| 40088 | gamma-glutamyltransferase | + | 2.3.2.2 | |
| 40088 | gelatinase | - | ||
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 68382 | lipase (C 14) | - | from API zym | |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 40088 | oxidase | - | ||
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 40088 | urease | - | 3.5.1.5 | |
| 68382 | valine arylamidase | - | from API zym |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|
| 66792 | ASM1591047v1 assembly for Acinetobacter baumannii ATCC 17961 | complete | GCA_015910475   | 470.12449  | 470 | 99.11 | |
| 124043 | ASM4505578v1 assembly for Acinetobacter baumannii ATCC 17961 | contig | GCA_045055785 | 470 | 77.61 | | |
| 66792 | Acinetobacter baumannii ATCC 17961 | contig | 470.2202 | 470 | 36.3 | |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Acinetobacter baumannii in human body louse. | La Scola B, Raoult D. | Emerg Infect Dis | 10.3201/eid1009.040242 | 2004 | | |
| In silico and in vitro comparative analysis of 79 Acinetobacter baumannii clinical isolates. | Scarrone M, Turner D, Dion M, Tremblay D, Moineau S. | Microbiol Spectr | 10.1128/spectrum.02849-24 | 2025 | | |
| Variation in type IV pilus stability modulates DNA uptake and biofilm formation. | Yu Y, Mahdi R, Al-Hilfy Leon A, Vo N, Lofgren R, Mutabazi JL, Piepenbrink KH. | J Biol Chem | 10.1016/j.jbc.2025.110787 | 2025 | | |
| A phosphorylation signal activates genome-wide transcriptional control by BfmR, the global regulator of Acinetobacter resistance and virulence. | Raustad N, Dai Y, Iinishi A, Mohapatra A, Soo MW, Hay E, Hernandez GM, Geisinger E. | Nucleic Acids Res | 10.1093/nar/gkaf063 | 2025 | | |
| Natural peptides and their synthetic congeners acting against Acinetobacter baumannii through the membrane and cell wall: latest progress. | Kumar G. | RSC Med Chem | 10.1039/d4md00745j | 2025 | | |
| Acinetobacter baumannii Regulates Its Stress Responses via the BfmRS Two-Component Regulatory System. | Palethorpe S, Farrow JM, Wells G, Milton ME, Actis LA, Cavanagh J, Pesci EC. | J Bacteriol | 10.1128/jb.00494-21 | 2022 | | |
| Subinhibitory Concentrations of Clinically-Relevant Antimicrobials Affect Resistance-Nodulation-Division Family Promoter Activity in Acinetobacter baumannii. | Prieto Martin Gil S, Tajuelo A, Lopez-Siles M, McConnell MJ. | Front Microbiol | 10.3389/fmicb.2021.780201 | 2021 | | |
| Growth and Distribution of Bacteria in Contaminated Whole Blood and Derived Blood Components. | Gravemann U, Handke W, Schulze TJ, Seltsam A. | Transfus Med Hemother | 10.1159/000536242 | 2024 | | |
| Comprehensive Approaches to Combatting Acinetobacter baumannii Biofilms: From Biofilm Structure to Phage-Based Therapies. | Grygiel I, Bajrak O, Wojcicki M, Krusiec K, Jonczyk-Matysiak E, Gorski A, Majewska J, Letkiewicz S. | Antibiotics (Basel) | 10.3390/antibiotics13111064 | 2024 | | |
| Testing the Luedemann hypothesis: the discovery of novel antimicrobials from slow-growing microbes from nutrient-limited environments. | Lin B, Woo S, Philbrick A, Bacsa J, Laskey E, Mehra N, Gondil VS, Mei JA, Jones G, Pavelka MS, Dziejman M, Shutter DA, Melander C, Perritt AM, Jakober R, Shen Y, Chang W-C, Quave CL, Dunman PM, Luedemann G. | mSphere | 10.1128/msphere.00367-25 | 2025 | | |
| Novel Phage Lysin Abp013 against Acinetobacter baumannii. | Chu JJK, Poh WH, Hasnuddin NTB, Hew EY, Dam LC, Sahili AE, Rice SA, Goh BC. | Antibiotics (Basel) | 10.3390/antibiotics11020169 | 2022 | | |
| Isolation and characterization of a VHH targeting the Acinetobacter baumannii cell surface protein CsuA/B. | Lei EK, Ryan S, van Faassen H, Foss M, Robotham A, Baltat I, Fulton K, Henry KA, Chen W, Hussack G. | Appl Microbiol Biotechnol | 10.1007/s00253-023-12594-1 | 2023 | | |
| Metabolism | CsrA Supports both Environmental Persistence and Host-Associated Growth of Acinetobacter baumannii. | Farrow JM, Wells G, Palethorpe S, Adams MD, Pesci EC. | Infect Immun | 10.1128/iai.00259-20 | 2020 | |
| Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii. | Tan Y, Su J, Fu M, Zhang H, Zeng H. | Bioengineering (Basel) | 10.3390/bioengineering10010035 | 2022 | | |
| Metabolism | Potential Mechanisms of Mucin-Enhanced Acinetobacter baumannii Virulence in the Mouse Model of Intraperitoneal Infection. | Harris G, Holbein BE, Zhou H, Xu HH, Chen W. | Infect Immun | 10.1128/iai.00591-19 | 2019 | |
| Genetics | Acinetobacter baumannii IC2 and IC5 Isolates with Co-Existing blaOXA-143-like and blaOXA-72 and Exhibiting Strong Biofilm Formation in a Mexican Hospital. | Moreno-Manjon J, Castillo-Ramirez S, Jolley KA, Maiden MCJ, Gayosso-Vazquez C, Fernandez-Vazquez JL, Mateo-Estrada V, Giono-Cerezo S, Alcantar-Curiel MD. | Microorganisms | 10.3390/microorganisms11092316 | 2023 | |
| CsrA-Controlled Proteins Reveal New Dimensions of Acinetobacter baumannii Desiccation Tolerance. | Oda Y, Shapiro MM, Lewis NM, Zhong X, Huse HK, Zhong W, Bruce JE, Manoil C, Harwood CS. | J Bacteriol | 10.1128/jb.00479-21 | 2022 | | |
| Advanced biomaterial agent from chitosan/poloxamer 407-based thermosensitive hydrogen containing biosynthesized silver nanoparticles using Eucalyptus camaldulensis leaf extract. | Wunnoo S, Lorenzo-Leal AC, Voravuthikunchai SP, Bach H. | PLoS One | 10.1371/journal.pone.0291505 | 2023 | | |
| Outer membrane vesicles as a platform for the discovery of antibodies to bacterial pathogens. | Lei EK, Azmat A, Henry KA, Hussack G. | Appl Microbiol Biotechnol | 10.1007/s00253-024-13033-5 | 2024 | | |
| Metabolism | Desiccation tolerance in Acinetobacter baumannii is mediated by the two-component response regulator BfmR. | Farrow JM, Wells G, Pesci EC. | PLoS One | 10.1371/journal.pone.0205638 | 2018 | |
| Linearization of the Brevicidine and Laterocidine Lipopeptides Yields Analogues That Retain Full Antibacterial Activity. | Ballantine RD, Al Ayed K, Bann SJ, Hoekstra M, Martin NI, Cochrane SA. | J Med Chem | 10.1021/acs.jmedchem.3c00308 | 2023 | | |
| Synthesis and structure-activity relationship studies of N-terminal analogues of the lipopeptide antibiotics brevicidine and laterocidine. | Ballantine RD, Al Ayed K, Bann SJ, Hoekstra M, Martin NI, Cochrane SA. | RSC Med Chem | 10.1039/d2md00281g | 2022 | | |
| Enzymology | Virulence profiles and innate immune responses against highly lethal, multidrug-resistant nosocomial isolates of Acinetobacter baumannii from a tertiary care hospital in Mexico. | Rosales-Reyes R, Gayosso-Vazquez C, Fernandez-Vazquez JL, Jarillo-Quijada MD, Rivera-Benitez C, Santos-Preciado JI, Alcantar-Curiel MD. | PLoS One | 10.1371/journal.pone.0182899 | 2017 | |
| Location, Location, Location: Establishing Design Principles for New Antibacterials from Ferric Siderophore Transport Systems. | Luo VC, Peczuh MW. | Molecules | 10.3390/molecules29163889 | 2024 | | |
| Pathogenicity | Characterization of carbapenem-resistant hypervirulent Acinetobacter baumannii strains isolated from hospitalized patients in the mid-south region of China. | Li J, Yu T, Luo Y, Peng JY, Li YJ, Tao XY, Hu YM, Wang HC, Zou MX. | BMC Microbiol | 10.1186/s12866-020-01957-7 | 2020 | |
| Safety and immunogenicity of a new glycoengineered vaccine against Acinetobacter baumannii in mice. | Li X, Pan C, Liu Z, Sun P, Hua X, Feng E, Yu Y, Wu J, Zhu L, Wang H. | Microb Biotechnol | 10.1111/1751-7915.13770 | 2022 | | |
| Enzymology | Acute intraperitoneal infection with a hypervirulent Acinetobacter baumannii isolate in mice. | Harris G, KuoLee R, Xu HH, Chen W. | Sci Rep | 10.1038/s41598-019-43000-4 | 2019 | |
| Overexpression of BIT33_RS14560 Enhances the Biofilm Formation and Virulence of Acinetobacter baumannii. | Yang R, Lai B, Liao K, Liu B, Huang L, Li S, Gu J, Lin Z, Chen Y, Wang S, Qiu Y, Deng J, Chen S, Zhuo C, Zhou Y. | Front Microbiol | 10.3389/fmicb.2022.867770 | 2022 | | |
| Carbapenem-Resistant Acinetobacter baumannii in Three Tertiary Care Hospitals in Mexico: Virulence Profiles, Innate Immune Response and Clonal Dissemination. | Alcantar-Curiel MD, Rosales-Reyes R, Jarillo-Quijada MD, Gayosso-Vazquez C, Fernandez-Vazquez JL, Toledano-Tableros JE, Giono-Cerezo S, Garza-Villafuerte P, Lopez-Huerta A, Vences-Vences D, Morfin-Otero R, Rodriguez-Noriega E, Lopez-Alvarez MDR, Espinosa-Sotero MDC, Santos-Preciado JI. | Front Microbiol | 10.3389/fmicb.2019.02116 | 2019 | | |
| The Immune Response against Acinetobacter baumannii, an Emerging Pathogen in Nosocomial Infections. | Garcia-Patino MG, Garcia-Contreras R, Licona-Limon P. | Front Immunol | 10.3389/fimmu.2017.00441 | 2017 | | |
| Pathogenicity | Antimicrobial activity of nanoemulsion in combination with cetylpyridinium chloride in multidrug-resistant Acinetobacter baumannii. | Hwang YY, Ramalingam K, Bienek DR, Lee V, You T, Alvarez R. | Antimicrob Agents Chemother | 10.1128/aac.02109-12 | 2013 | |
| Whole-cell biosensing by siderophore-based molecular recognition and localized surface plasmon resonance. | Hu J, Ghosh M, Miller MJ, Bohn PW. | Anal Methods | 10.1039/c8ay02180e | 2019 | | |
| Metabolism | Glycomics Microarrays Reveal Differential In Situ Presentation of the Biofilm Polysaccharide Poly-N-acetylglucosamine on Acinetobacter baumannii and Staphylococcus aureus Cell Surfaces. | Flannery A, Le Berre M, Pier GB, O'Gara JP, Kilcoyne M. | Int J Mol Sci | 10.3390/ijms21072465 | 2020 | |
| Pathogenicity | New Treatment Options against Carbapenem-Resistant Acinetobacter baumannii Infections. | Isler B, Doi Y, Bonomo RA, Paterson DL. | Antimicrob Agents Chemother | 10.1128/aac.01110-18 | 2019 | |
| Conjugation to Native and Nonnative Triscatecholate Siderophores Enhances Delivery and Antibacterial Activity of a beta-Lactam to Gram-Negative Bacterial Pathogens. | Motz RN, Guo C, Sargun A, Walker GT, Sassone-Corsi M, Raffatellu M, Nolan EM. | J Am Chem Soc | 10.1021/jacs.3c14490 | 2024 | | |
| A mouse model of Acinetobacter baumannii-associated pneumonia using a clinically isolated hypervirulent strain. | Harris G, Kuo Lee R, Lam CK, Kanzaki G, Patel GB, Xu HH, Chen W. | Antimicrob Agents Chemother | 10.1128/aac.00944-13 | 2013 | | |
| Siderophores as "Trojan Horses": tackling multidrug resistance? | de Carvalho CC, Fernandes P. | Front Microbiol | 10.3389/fmicb.2014.00290 | 2014 | | |
| Conjugation of Aztreonam, a Synthetic Monocyclic beta-Lactam Antibiotic, to a Siderophore Mimetic Significantly Expands Activity Against Gram-Negative Bacteria. | Liu R, Miller PA, Miller MJ. | ACS Infect Dis | 10.1021/acsinfecdis.1c00458 | 2021 | | |
| Siderophore-Antibiotic Conjugate Design: New Drugs for Bad Bugs? | Negash KH, Norris JKS, Hodgkinson JT. | Molecules | 10.3390/molecules24183314 | 2019 | | |
| Role of macrophages in early host resistance to respiratory Acinetobacter baumannii infection. | Qiu H, KuoLee R, Harris G, Van Rooijen N, Patel GB, Chen W. | PLoS One | 10.1371/journal.pone.0040019 | 2012 | | |
| Transcriptome | Complete genome sequence of hypervirulent and outbreak-associated Acinetobacter baumannii strain LAC-4: epidemiology, resistance genetic determinants and potential virulence factors. | Ou HY, Kuang SN, He X, Molgora BM, Ewing PJ, Deng Z, Osby M, Chen W, Xu HH. | Sci Rep | 10.1038/srep08643 | 2015 | |
| Clinical and Pathophysiological Overview of Acinetobacter Infections: a Century of Challenges. | Wong D, Nielsen TB, Bonomo RA, Pantapalangkoor P, Luna B, Spellberg B. | Clin Microbiol Rev | 10.1128/cmr.00058-16 | 2017 | | |
| Inactivation of phospholipase D diminishes Acinetobacter baumannii pathogenesis. | Jacobs AC, Hood I, Boyd KL, Olson PD, Morrison JM, Carson S, Sayood K, Iwen PC, Skaar EP, Dunman PM. | Infect Immun | 10.1128/iai.00889-09 | 2010 | | |
| The Natural Product Essramycin and Three of Its Isomers Are Devoid of Antibacterial Activity. | Wang H, Hesek D, Lee M, Lastochkin E, Oliver AG, Chang M, Mobashery S. | J Nat Prod | 10.1021/acs.jnatprod.6b00057 | 2016 | | |
| Targeting virulence: salmochelin modification tunes the antibacterial activity spectrum of beta-lactams for pathogen-selective killing of Escherichia coli. | Chairatana P, Zheng T, Nolan EM. | Chem Sci | 10.1039/c5sc00962f | 2015 | | |
| Enzymology | Role of NADPH phagocyte oxidase in host defense against acute respiratory Acinetobacter baumannii infection in mice. | Qiu H, Kuolee R, Harris G, Chen W. | Infect Immun | 10.1128/iai.01029-08 | 2009 | |
| Acinetobacter baumannii infection inhibits airway eosinophilia and lung pathology in a mouse model of allergic asthma. | Qiu H, Kuolee R, Harris G, Zhou H, Miller H, Patel GB, Chen W. | PLoS One | 10.1371/journal.pone.0022004 | 2011 | | |
| Metal Sequestration and Antimicrobial Activity of Human Calprotectin Are pH-Dependent. | Rosen T, Nolan EM. | Biochemistry | 10.1021/acs.biochem.0c00359 | 2020 | | |
| Neutrophils play an important role in host resistance to respiratory infection with Acinetobacter baumannii in mice. | van Faassen H, KuoLee R, Harris G, Zhao X, Conlan JW, Chen W. | Infect Immun | 10.1128/iai.00762-07 | 2007 | | |
| Persistence of Pathogens on Inanimate Surfaces: A Narrative Review. | Wissmann JE, Kirchhoff L, Bruggemann Y, Todt D, Steinmann J, Steinmann E. | Microorganisms | 10.3390/microorganisms9020343 | 2021 | | |
| Initial Biochemical and Functional Evaluation of Murine Calprotectin Reveals Ca(II)-Dependence and Its Ability to Chelate Multiple Nutrient Transition Metal Ions. | Hadley RC, Gu Y, Nolan EM. | Biochemistry | 10.1021/acs.biochem.8b00309 | 2018 | | |
| Pathogenicity | Synthesis and evaluation of 1,2,4-triazolo[1,5-a]pyrimidines as antibacterial agents against Enterococcus faecium. | Wang H, Lee M, Peng Z, Blazquez B, Lastochkin E, Kumarasiri M, Bouley R, Chang M, Mobashery S. | J Med Chem | 10.1021/jm501831g | 2015 | |
| Pathogenicity | Structure-activity relationship for the oxadiazole class of antibiotics. | Spink E, Ding D, Peng Z, Boudreau MA, Leemans E, Lastochkin E, Song W, Lichtenwalter K, O'Daniel PI, Testero SA, Pi H, Schroeder VA, Wolter WR, Antunes NT, Suckow MA, Vakulenko S, Chang M, Mobashery S. | J Med Chem | 10.1021/jm501661f | 2015 | |
| Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism. | Zhong W, Pasunooti KK, Balamkundu S, Wong YH, Nah Q, Gadi V, Gnanakalai S, Chionh YH, McBee ME, Gopal P, Lim SH, Olivier N, Buurman ET, Dick T, Liu CF, Lescar J, Dedon PC. | J Med Chem | 10.1021/acs.jmedchem.9b00582 | 2019 | | |
| Pathogenicity | Discovery of a new class of non-beta-lactam inhibitors of penicillin-binding proteins with Gram-positive antibacterial activity. | O'Daniel PI, Peng Z, Pi H, Testero SA, Ding D, Spink E, Leemans E, Boudreau MA, Yamaguchi T, Schroeder VA, Wolter WR, Llarrull LI, Song W, Lastochkin E, Kumarasiri M, Antunes NT, Espahbodi M, Lichtenwalter K, Suckow MA, Vakulenko S, Mobashery S, Chang M. | J Am Chem Soc | 10.1021/ja500053x | 2014 | |
| Advancements in antimicrobial nanoscale materials and self-assembling systems. | Doolan JA, Williams GT, Hilton KLF, Chaudhari R, Fossey JS, Goult BT, Hiscock JR. | Chem Soc Rev | 10.1039/d1cs00915j | 2022 | | |
| Phylogeny | Cultural and chemical characterization of CDC groups EO-2, M-5, and M-6, Moraxella (Moraxella) species, Oligella urethralis, Acinetobacter species, and Psychrobacter immobilis. | Moss CW, Wallace PL, Hollis DG, Weaver RE. | J Clin Microbiol | 10.1128/jcm.26.3.484-492.1988 | 1988 | |
| Genetics | Genome Sequences for Two Acinetobacter baumannii Strains Obtained Using the Unicycler Hybrid Assembly Pipeline. | Farrow JM 3rd, Pesci EC, Slade DJ | Microbiol Resour Announc | 10.1128/MRA.00017-21 | 2021 | |
| Cultivation | Biscatecholate-monohydroxamate mixed ligand siderophore-carbacephalosporin conjugates are selective sideromycin antibiotics that target Acinetobacter baumannii. | Wencewicz TA, Miller MJ | J Med Chem | 10.1021/jm400265k | 2013 | |
| Genetics | Identification and structural determination of the capsular polysaccharides from two Acinetobacter baumannii clinical isolates, MG1 and SMAL. | Fregolino E, Gargiulo V, Lanzetta R, Parrilli M, Holst O, Castro CD | Carbohydr Res | 10.1016/j.carres.2011.03.024 | 2011 | |
| The structure of the polysaccharide O-chain of the LPS from Acinetobacter baumannii strain ATCC 17961. | MacLean LL, Perry MB, Chen W, Vinogradov E | Carbohydr Res | 10.1016/j.carres.2008.12.026 | 2009 | | |
| Metabolism | CsrA Coordinates Compatible Solute Synthesis in Acinetobacter baumannii and Facilitates Growth in Human Urine. | Hubloher JJ, Schabacker K, Muller V, Averhoff B | Microbiol Spectr | 10.1128/Spectrum.01296-21 | 2021 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive138562.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
License