Mycobacterium smegmatis (DSM 43277, ATCC 101, ATCC 14468)

Name: Mycobacterium smegmatis (DSM 43277, ATCC 101, ATCC 14468)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 8315

Type strain

Culture col. no. DSM 43277 ATCC 101 ATCC 14468 NCIB 9953 NCTC 10265 1 more

NCBI tax ID(s) 1772

Special Collections DSMZ

History <- K. Kieslich, Schering 215 <- ATCC <- L.F. Bojalil, W-113 <- S. A. Waksman, 113 <- ATCC <- Hyg. Lab., Washington DC, 178 (Bacillus smegmatis)

Links

Mycobacterium smegmatis DSM 43277 is a human pathogen of the family Mycobacteriaceae.

human pathogen 16S sequence Bacteria

Name and taxonomic classification

SI-ID 46517

CT1967-01057,ATCC 14468,ATCC 101,NCIB 9953,NCTC 10265,CCUG 21818,CCUG 21820,CCUG 27844,CCUG 28063,NCIMB 9953,CCM 2300,CECT 3017,CCRC 10708,BCRC 10708,DSM 43277

@ref 20215

Last LPSN update 2026-02-09 11:19:40

Domain Bacteria

Phylum Actinomycetota

Class Actinomycetes

Order Mycobacteriales

Family Mycobacteriaceae

Genus Mycobacterium

Species Mycobacterium smegmatis

Full scientific name Mycobacterium smegmatis (Trevisan 1889) Lehmann and Neumann 1899 (Approved Lists 1980)

Synonyms (2)

"Bacillus smegmatis"
Mycolicibacterium smegmatis

BacDive ID	Other strains from **Mycobacterium smegmatis** (27)	Type strain
8324	M. smegmatis GA 735, Cornell 3, 14 133 0010, DSM 43756, ... (type strain)
8256	M. smegmatis Minetti 41, DSM 43479, SN 220
8309	M. smegmatis DSM 43059, CCM 1889, IMRU N 525, NCTC 525, ...
8310	M. smegmatis DSM 43061, CCM 2228, NCTC 523
8311	M. smegmatis 52-L-1, DSM 43078, IMRU 672
8312	M. smegmatis DSM 43079, IMRU 853
8313	M. smegmatis DSM 43080, IMRU 580
8314	M. smegmatis 52-Q-1, DSM 43081, IMRU 595
8316	M. smegmatis 74C, Schering 250, DSM 43286, ATCC 356, NCTC ...
8317	M. smegmatis 169, Schering 275, DSM 43299, ATCC 114, CCUG ...
8318	M. smegmatis DSM 43464, ATCC 27204, IMET 10646, SN 2
8319	M. smegmatis 607, DSM 43465, ATCC 607, NRRL B-692, SN ...
8320	M. smegmatis DSM 43466, IMRU 7992, SN 35
8321	M. smegmatis DSM 43467, IMRU 9822, SN 44
8322	M. smegmatis 114, DSM 43468, ATCC 27205, IMET 10647, IMRU ...
8323	M. smegmatis 7449, DSM 43469, IMET 10648, SN 46
8325	M. smegmatis DSM 44200, HKI 0056 (SG 987)
8326	M. smegmatis 987-M10, DSM 44201, HKI 0062
104243	M. smegmatis ST033288(HKI),
136747	M. smegmatis CIP 56.5, CCTM 170, NCTC 53
139485	M. smegmatis F21, CIP 73.26
143909	M. smegmatis CCUG 21821, ATCC 19979, NCTC 333
143910	M. smegmatis CCUG 21822, ATCC 23028
143911	M. smegmatis CCUG 21823, ATCC 23032
143912	M. smegmatis CCUG 21824, ATCC 23037
145167	M. smegmatis CCUG 27786
145276	M. smegmatis CCUG 28062, NCTC 3821

Morphology

Culture and growth conditions

Culture medium

@ref	Name	Growth	Medium link	Composition
10921	MIDDLEBROOK MEDIUM (DSMZ Medium 645)		Medium recipe at MediaDive	Name: MIDDLEBROOK MEDIUM (DSMZ Medium 645) Composition: Bacto Middlebrook 7H10 agar 20.9945 g/l Glycerol Distilled water
10921	LÖWENSTEIN-JENSEN MEDIUM (DSMZ Medium 354)		Medium recipe at MediaDive	Name: LÖWENSTEIN-JENSEN MEDIUM (DSMZ Medium 354) Composition: Potato flour 18.6104 g/l L-Asparagin 2.23325 g/l KH2PO4 1.55087 g/l Mg-citrate 0.372208 g/l Malachite green 0.248139 g/l MgSO4 0.148883 g/l Glycerol Fresh egg mixture Distilled water

Culture temp

@ref	Growth	Type	Temperature (°C)
10921	positive	growth	37

Physiology and metabolism

Isolation, sampling and environmental information

Interaction and safety

Risk assessment

@ref	Pathogenicity human	Pathogenicity animal	Biosafety level	Biosafety level comment
10921			2	Risk group (German classification) According to TRBA 466

Sequence information

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Mycobacterium smegmatis strain ATCC 14468 16S ribosomal RNA gene, partial sequence	JQ348119	206	1772
20218	M.smegmatis 16S ribosomal RNA gene	M59281	148	1772
20218	Mycobacterium smegmatis 16S rRNA gene	X52922	1454	1772

Genome-based predictions

Literature

Topic	Title	Authors	Journal	DOI	Year
Metabolism	Estrogen Degraders and Estrogen Degradation Pathway Identified in an Activated Sludge.	Chen YL, Fu HY, Lee TH, Shih CJ, Huang L, Wang YS, Ismail W, Chiang YR.	Appl Environ Microbiol	10.1128/aem.00001-18	2018
	Rapidly growing, acid fast bacteria. I. Species' descriptions of Mycobacterium phlei Lehmann and Neumann and Mycobacterium smegmatis (Trevisan) Lehmann and Neumann.	GORDON RE, SMITH MM.	J Bacteriol	10.1128/jb.66.1.41-48.1953	1953
	In vitro evaluation the spectrum of antibacterial activity of botanical extracts and activity enhancement with outer membrane permeabilizers.	Gregory C, Langland J.	BMC Complement Med Ther	10.1186/s12906-025-05147-8	2025
	Spore-Derived Isolates from a Single Basidiocarp of Bioluminescent Omphalotus olivascens Reveal Multifaceted Phenotypic and Physiological Variations.	Diaz R, Bermudes D.	Microorganisms	10.3390/microorganisms13010059	2025
	Exploring the versatility of heterocyclic compounds containing nitrogen atoms (triazoles): a comprehensive review.	Akram M, Tamminana R.	RSC Adv	10.1039/d5ra07255g	2025
	A rationally designed antimicrobial peptide from structural and functional insights of Clostridioides difficile translation initiation factor 1.	Alanis E, Aguilar F, Banaei N, Dean FB, Villarreal A, Alanis M, Lozano K, Bullard JM, Zhang Y.	Microbiol Spectr	10.1128/spectrum.02773-23	2024
	Gold Nanoparticle-Enhanced Recombinase Polymerase Amplification for Rapid Visual Detection of Mycobacterium tuberculosis.	Saikaew S, Sangboonruang S, Pongsararuk R, Srilohasin P, Butr-Indr B, Intorasoot S, Phunpae P, Tharinjaroen CS, Arunothong S, Panyasit W, Chaiprasert A, Tragoolpua K, Wattananandkul U.	Biosensors (Basel)	10.3390/bios15090607	2025
	Extracts of Ansellia africana and Platycarpha glomerata exhibit antibacterial activities against some respiratory tract, skin and soft tissue infections implicated bacteria	Penduka D, Mthembu W, Cele KH, Mosa RA, Zobolo AM, Opoku AR.	S Afr J Bot		2018
	HPLC-DAD and UHPLC/QTOF-MS Analysis of Polyphenols in Extracts of the African Species Combretum padoides, C. zeyheri and C. psidioides Related to Their Antimycobacterial Activity.	Fyhrquist P, Salih EYA, Helenius S, Laakso I, Julkunen-Tiitto R.	Antibiotics (Basel)	10.3390/antibiotics9080459	2020
Genetics	Chemical, Bioactivity, and Biosynthetic Screening of Epiphytic Fungus Zasmidium pseudotsugae.	Gonzalez-Montiel GA, Kaweesa EN, Feau N, Hamelin RC, Stone JK, Loesgen S.	Molecules	10.3390/molecules25102358	2020
	Potential Anti-Tuberculosis Activity of the Extracts and Their Active Components of Anogeissus Leiocarpa (DC.) Guill. and Perr. with Special Emphasis on Polyphenols.	Salih EYA, Julkunen-Tiitto R, Luukkanen O, Sipi M, Fahmi MKM, Fyhrquist PJ.	Antibiotics (Basel)	10.3390/antibiotics9070364	2020
	A Metabolic-Tag-Based Method for Assessing the Permeation of Small Molecules Across the Mycomembrane in Live Mycobacteria.	Liu Z, Lepori I, Chordia MD, Dalesandro BE, Guo T, Dong J, Siegrist MS, Pires MM.	Angew Chem Int Ed Engl	10.1002/anie.202217777	2023
	Antimicrobial activity of the volatile substances from essential oils.	Abers M, Schroeder S, Goelz L, Sulser A, St Rose T, Puchalski K, Langland J.	BMC Complement Med Ther	10.1186/s12906-021-03285-3	2021
Metabolism	L,D-Transpeptidase Specific Probe Reveals Spatial Activity of Peptidoglycan Cross-Linking.	Pidgeon SE, Apostolos AJ, Nelson JM, Shaku M, Rimal B, Islam MN, Crick DC, Kim SJ, Pavelka MS, Kana BD, Pires MM.	ACS Chem Biol	10.1021/acschembio.9b00427	2019
	Antibacterial Potential of Secondary Metabolites from Indonesian Marine Bacterial Symbionts.	Nofiani R, Weisberg AJ, Tsunoda T, Panjaitan RGP, Brilliantoro R, Chang JH, Philmus B, Mahmud T.	Int J Microbiol	10.1155/2020/8898631	2020
Pathogenicity	Synthesis of New Fluoro-Benzimidazole Derivatives as an Approach towards the Discovery of Novel Intestinal Antiseptic Drug Candidates.	Cevik UA, Saglik BN, Ozkay Y, Canturk Z, Bueno J, Demirci F, Koparal AS.	Curr Pharm Des	10.2174/1381612822666161201150131	2017
	Construction of a Bacterial Lipidomics Analytical Platform: Pilot Validation with Bovine Paratuberculosis Serum.	Wood PL, Erol E.	Metabolites	10.3390/metabo13070809	2023
Pathogenicity	Antimycobacterial Activities of Endolysins Derived From a Mycobacteriophage, BTCU-1.	Lai MJ, Liu CC, Jiang SJ, Soo PC, Tu MH, Lee JJ, Chen YH, Chang KC.	Molecules	10.3390/molecules201019277	2015
	Modifying Escherichia coli to mimic Shigella for medical microbiology laboratory teaching: a new strategy to improve biosafety in class.	Zhang G, Liu J, He Y, Du Y, Xu L, Chen T, Guo Y, Fu H, Li A, Tian Y, Hu Y, Yang C, Lu M, Deng X, Wang J, Lu N.	Front Cell Infect Microbiol	10.3389/fcimb.2023.1257361	2023
	Antimycobacterial activity of ellagitannin and ellagic acid derivate rich crude extracts and fractions of five selected species of Terminalia used for treatment of infectious diseases in African traditional medicine	Fyhrquist P, Laakso I, Garcia Marco S, Julkunen-Tiitto R, Hiltunen R.	S Afr J Bot	10.1016/j.sajb.2013.08.018	2014
	Precursor-Directed Biosynthesis of Aminofulvenes: New Chalanilines from Endophytic Fungus Chalara sp.	Khoshbakht M, Srey J, Adpressa DA, Jagels A, Loesgen S.	Molecules	10.3390/molecules26154418	2021
Metabolism	Efflux Pump Inhibitors Against Nontuberculous Mycobacteria.	Rindi L.	Int J Mol Sci	10.3390/ijms21124191	2020
	Mutation at G103 of MtbFtsZ Altered their Sensitivity to Coumarins.	Sridevi D, Sudhakar KU, Ananthathatmula R, Nankar RP, Doble M.	Front Microbiol	10.3389/fmicb.2017.00578	2017
Enzymology	Cytotoxic Indolocarbazoles from Actinomadura melliaura ATCC 39691.	Shaaban KA, Elshahawi SI, Wang X, Horn J, Kharel MK, Leggas M, Thorson JS.	J Nat Prod	10.1021/acs.jnatprod.5b00429	2015
	Antibacterial and Antifungal Alkaloids from Asian Angiosperms: Distribution, Mechanisms of Action, Structure-Activity, and Clinical Potentials.	Sulaiman M, Jannat K, Nissapatorn V, Rahmatullah M, Paul AK, de Lourdes Pereira M, Rajagopal M, Suleiman M, Butler MS, Break MKB, Weber JF, Wilairatana P, Wiart C.	Antibiotics (Basel)	10.3390/antibiotics11091146	2022
	Structural revision of sesbagrandiflorains A and B, and synthesis and biological evaluation of 6-methoxy-2-arylbenzofuran derivatives.	Noviany N, Samadi A, Carpenter EL, Abugrain ME, Hadi S, Purwitasari N, Indra G, Indra A, Mahmud T.	J Nat Med	10.1007/s11418-020-01445-2	2021
Pathogenicity	Impact of chlorine dioxide gas sterilization on nosocomial organism viability in a hospital room.	Lowe JJ, Gibbs SG, Iwen PC, Smith PW, Hewlett AL.	Int J Environ Res Public Health	10.3390/ijerph10062596	2013
Metabolism	Self-Resistance during Muraymycin Biosynthesis: a Complementary Nucleotidyltransferase and Phosphotransferase with Identical Modification Sites and Distinct Temporal Order.	Cui Z, Wang XC, Liu X, Lemke A, Koppermann S, Ducho C, Rohr J, Thorson JS, Van Lanen SG.	Antimicrob Agents Chemother	10.1128/aac.00193-18	2018
	Investigation of Copaifera genus as a new source of antimycobaterial agents.	Alves JA, Abrao F, da Silva Moraes T, Damasceno JL, Dos Santos Moraes MF, Sola Veneziani RC, Ambrosio SR, Bastos JK, Dantas Miranda ML, Gomes Martins CH.	Future Sci OA	10.2144/fsoa-2020-0018	2020
	Ethnomedicinal, Phytochemical and Pharmacological Investigations of Tetradenia riparia (Hochst.) Codd (Lamiaceae).	Panda SK, Gazim ZC, Swain SS, Bento MCVA, Sena JDS, Mukazayire MJ, Van Puyvelde L, Luyten W.	Front Pharmacol	10.3389/fphar.2022.896078	2022
Pathogenicity	In vitro activities of tigecycline and 10 other antimicrobials against nonpigmented rapidly growing mycobacteria.	Fernandez-Roblas R, Martin-de-Hijas NZ, Fernandez-Martinez AI, Garcia-Almeida D, Gadea I, Esteban J.	Antimicrob Agents Chemother	10.1128/aac.00695-08	2008
	Corynebacterium accolens Has Antimicrobial Activity against Staphylococcus aureus and Methicillin-Resistant S. aureus Pathogens Isolated from the Sinonasal Niche of Chronic Rhinosinusitis Patients.	Menberu MA, Liu S, Cooksley C, Hayes AJ, Psaltis AJ, Wormald PJ, Vreugde S.	Pathogens	10.3390/pathogens10020207	2021
Pathogenicity	Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).	Nash KA.	Antimicrob Agents Chemother	10.1128/aac.47.10.3053-3060.2003	2003
	Biofilm development by potentially pathogenic non-pigmented rapidly growing mycobacteria.	Esteban J, Martin-de-Hijas NZ, Kinnari TJ, Ayala G, Fernandez-Roblas R, Gadea I.	BMC Microbiol	10.1186/1471-2180-8-184	2008
Pathogenicity	Novel cyclic lipodepsipeptide from Pseudomonas syringae pv. lachrymans strain 508 and syringopeptin antimicrobial activities.	Grgurina I, Bensaci M, Pocsfalvi G, Mannina L, Cruciani O, Fiore A, Fogliano V, Sorensen KN, Takemoto JY.	Antimicrob Agents Chemother	10.1128/aac.49.12.5037-5045.2005	2005
Pathogenicity	Syntheses and evaluation of multicaulin and miltirone-like compounds as antituberculosis agents.	Burmaoglu S, Secinti H, Mozioglu E, Goren AC, Altundas R, Secen H.	J Enzyme Inhib Med Chem	10.1080/14756366.2017.1337758	2017
Pathogenicity	Molecular analysis of kanamycin and viomycin resistance in Mycobacterium smegmatis by use of the conjugation system.	Taniguchi H, Chang B, Abe C, Nikaido Y, Mizuguchi Y, Yoshida SI.	J Bacteriol	10.1128/jb.179.15.4795-4801.1997	1997
Phylogeny	rpoB-based identification of nonpigmented and late-pigmenting rapidly growing mycobacteria.	Adekambi T, Colson P, Drancourt M.	J Clin Microbiol	10.1128/jcm.41.12.5699-5708.2003	2003
Biotechnology	Medicinal properties and conservation of Pelargonium sidoides DC.	Moyo M, Van Staden J.	J Ethnopharmacol	10.1016/j.jep.2014.01.009	2014
Pathogenicity	In Vitro Antibacterial Activity of Rhodanine Derivatives against Pathogenic Clinical Isolates.	AbdelKhalek A, Ashby CR, Patel BA, Talele TT, Seleem MN.	PLoS One	10.1371/journal.pone.0164227	2016
Genetics	Identification and characterization of a novel trehalose synthase gene derived from saline-alkali soil metagenomes.	Jiang L, Lin M, Zhang Y, Li Y, Xu X, Li S, He Huang.	PLoS One	10.1371/journal.pone.0077437	2013
	Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds.	Li Petri G, Raimondi MV, Spano V, Holl R, Barraja P, Montalbano A.	Top Curr Chem (Cham)	10.1007/s41061-021-00347-5	2021
	The Genus Terminalia (Combretaceae): An Ethnopharmacological, Phytochemical and Pharmacological Review.	Zhang XR, Kaunda JS, Zhu HT, Wang D, Yang CR, Zhang YJ.	Nat Prod Bioprospect	10.1007/s13659-019-00222-3	2019
	A Novel Assay for Detection of Methicillin-Resistant Staphylococcus aureus Directly From Clinical Samples.	McClure JA, Conly JM, Obasuyi O, Ward L, Ugarte-Torres A, Louie T, Zhang K.	Front Microbiol	10.3389/fmicb.2020.01295	2020
Pathogenicity	Zafirlukast inhibits complexation of Lsr2 with DNA and growth of Mycobacterium tuberculosis.	Pinault L, Han JS, Kang CM, Franco J, Ronning DR.	Antimicrob Agents Chemother	10.1128/aac.02407-12	2013
Metabolism	Last step in the conversion of trehalose to glycogen: a mycobacterial enzyme that transfers maltose from maltose 1-phosphate to glycogen.	Elbein AD, Pastuszak I, Tackett AJ, Wilson T, Pan YT.	J Biol Chem	10.1074/jbc.m109.033944	2010
Pathogenicity	Synthesis of N-substituted 2-[(1E)-alkenyl]-4-(1H)-quinolone derivatives as antimycobacterial agents against non-tubercular mycobacteria.	Wube AA, Bucar F, Hochfellner C, Blunder M, Bauer R, Hufner A.	Eur J Med Chem	10.1016/j.ejmech.2011.02.062	2011
Metabolism	Evidence for the synthesis of peptidoglycan by spheroplasts of Mycobacterium smegmatis ATCC-14468.	Murty MV, Venkitasubramanian TA.	Ann Microbiol (Paris)	10.1016/s0769-2609(84)80078-2	1984
Metabolism	Production of androgens by microbial transformation of progesterone in vitro: a model for androgen production in rivers.	Jenkins RL, Wilson EM, Angus RA, Howell WM, Kirk M, Moore R, Nance M, Brown A.	Environ Health Perspect	10.1289/ehp.7161	2004
Pathogenicity	Thiopurine drugs azathioprine and 6-mercaptopurine inhibit Mycobacterium paratuberculosis growth in vitro.	Shin SJ, Collins MT.	Antimicrob Agents Chemother	10.1128/aac.00678-07	2008
	Repurposing celecoxib as a topical antimicrobial agent.	Thangamani S, Younis W, Seleem MN.	Front Microbiol	10.3389/fmicb.2015.00750	2015
Pathogenicity	Sequence and analysis of the rpoB gene of Mycobacterium smegmatis.	Hetherington SV, Watson AS, Patrick CC.	Antimicrob Agents Chemother	10.1128/aac.39.9.2164	1995
Metabolism	Cloning and expression of the gene for a novel protein from Mycobacterium smegmatis with functional similarity to eukaryotic calmodulin.	Reddy PT, Prasad CR, Reddy PH, Reeder D, McKenney K, Jaffe H, Dimitrova MN, Ginsburg A, Peterkofsky A, Murthy PS.	J Bacteriol	10.1128/jb.185.17.5263-5268.2003	2003
	Targeting the trehalose utilization pathways of Mycobacterium tuberculosis.	Thanna S, Sucheck SJ.	Medchemcomm	10.1039/c5md00376h	2016
	Major Bioactive Alkaloids and Biological Activities of Tabernaemontana Species (Apocynaceae).	Naidoo CM, Naidoo Y, Dewir YH, Murthy HN, El-Hendawy S, Al-Suhaibani N.	Plants (Basel)	10.3390/plants10020313	2021
Pathogenicity	Determination of hydrophobicity on bacterial surfaces by nonionic surfactants.	Noda Y, Kanemasa Y.	J Bacteriol	10.1128/jb.167.3.1016-1019.1986	1986
	Antimicrobial and antioxidant activities of Cortex Magnoliae Officinalis and some other medicinal plants commonly used in South-East Asia.	Chan LW, Cheah EL, Saw CL, Weng W, Heng PW.	Chin Med	10.1186/1749-8546-3-15	2008
Phylogeny	Rapid identification of Rhodococcus equi by a PCR assay targeting the choE gene.	Ladron N, Fernandez M, Aguero J, Gonzalez Zorn B, Vazquez-Boland JA, Navas J.	J Clin Microbiol	10.1128/jcm.41.7.3241-3245.2003	2003
Enzymology	Molecular detection of Mycobacterium bovis and Mycobacterium bovis BCG (Pasteur) in soil.	Young JS, Gormley E, Wellington EM.	Appl Environ Microbiol	10.1128/aem.71.4.1946-1952.2005	2005
	Design, synthesis, and X-ray analysis of a glycoconjugate bound to Mycobacterium tuberculosis antigen 85C.	Ibrahim DA, Boucau J, Lajiness DH, Veleti SK, Trabbic KR, Adams SS, Ronning DR, Sucheck SJ.	Bioconjug Chem	10.1021/bc3004342	2012
Enzymology	Comparative evaluation of the new version of the INNO-LiPA Mycobacteria and genotype Mycobacterium assays for identification of Mycobacterium species from MB/BacT liquid cultures artificially inoculated with Mycobacterial strains.	Padilla E, Gonzalez V, Manterola JM, Perez A, Quesada MD, Gordillo S, Vilaplana C, Pallares MA, Molinos S, Sanchez MD, Ausina V.	J Clin Microbiol	10.1128/jcm.42.7.3083-3088.2004	2004
	Synthesis and antibacterial evaluation of a new series of N-Alkyl-2-alkynyl/(E)-alkenyl-4-(1H)-quinolones.	Wube A, Guzman JD, Hufner A, Hochfellner C, Blunder M, Bauer R, Gibbons S, Bhakta S, Bucar F.	Molecules	10.3390/molecules17078217	2012
Metabolism	Lead precipitation by Vibrio harveyi: evidence for novel quorum-sensing interactions.	Mire CE, Tourjee JA, O'Brien WF, Ramanujachary KV, Hecht GB.	Appl Environ Microbiol	10.1128/aem.70.2.855-864.2004	2004
Phylogeny	Use of randomly amplified polymorphic DNA as a means of developing genus- and strain-specific Streptomyces DNA probes.	Roberts MA, Crawford DL.	Appl Environ Microbiol	10.1128/aem.66.6.2555-2564.2000	2000
	Vulnerability of pathogenic biofilms to Micavibrio aeruginosavorus.	Kadouri D, Venzon NC, O'Toole GA.	Appl Environ Microbiol	10.1128/aem.01893-06	2007
Pathogenicity	Altered ribosomes in antibiotic-resistant mutants of Mycobacterium smegmatis.	Yamada T, Masuda K, Mizuguchi Y, Suga K.	Antimicrob Agents Chemother	10.1128/aac.9.5.817	1976
	Current updates on oxazolidinone and its significance.	Pandit N, Singla RK, Shrivastava B.	Int J Med Chem	10.1155/2012/159285	2012
Metabolism	Purification and characterization of mycobacterial phospholipase A: an activity associated with mycobacterial cutinase.	Parker SK, Curtin KM, Vasil ML.	J Bacteriol	10.1128/jb.01909-06	2007
	A comprehensive review on pharmacotherapeutics of herbal bioenhancers.	Dudhatra GB, Mody SK, Awale MM, Patel HB, Modi CM, Kumar A, Kamani DR, Chauhan BN.	ScientificWorldJournal	10.1100/2012/637953	2012
Pathogenicity	Lipoarabinomannan and related glycoconjugates: structure, biogenesis and role in Mycobacterium tuberculosis physiology and host-pathogen interaction.	Mishra AK, Driessen NN, Appelmelk BJ, Besra GS.	FEMS Microbiol Rev	10.1111/j.1574-6976.2011.00276.x	2011
	Prospecting environmental mycobacteria: combined molecular approaches reveal unprecedented diversity.	Pontiroli A, Khera TT, Oakley BB, Mason S, Dowd SE, Travis ER, Erenso G, Aseffa A, Courtenay O, Wellington EM.	PLoS One	10.1371/journal.pone.0068648	2013
Phylogeny	Differential identification of Mycobacterium fortuitum and Mycobacterium chelonei.	David HL, Traore I, Feuillet A.	J Clin Microbiol	10.1128/jcm.13.1.6-9.1981	1981
	Assessment of mycobacterial viability by RNA amplification.	van der Vliet GM, Schepers P, Schukkink RA, van Gemen B, Klatser PR.	Antimicrob Agents Chemother	10.1128/aac.38.9.1959	1994
	Growth of group IV mycobacteria on medium containing various saturated and unsaturated fatty acids.	Saito H, Tomioka H, Yoneyama T.	Antimicrob Agents Chemother	10.1128/aac.26.2.164	1984
Pathogenicity	Analysis of ribosomes from viomycin-sensitive and -resistant strains of Mycobacterium smegmatis.	Yamada T, Masuda K, Shoji K, Hori M.	J Bacteriol	10.1128/jb.112.1.1-6.1972	1972
Metabolism	Pleiotropic antibiotic resistance mutations associated with ribosomes and ribosomal subunits in Mycobacterium smegmatis.	Yamada T, Masuda K, Shoji K, Hori M.	Antimicrob Agents Chemother	10.1128/aac.6.1.46	1974
	Genus-specific epitope on the 60-kilodalton Legionella heat shock protein recognized by a monoclonal antibody.	Steinmetz I, Rheinheimer C, Hubner I, Bitter-Suermann D.	J Clin Microbiol	10.1128/jcm.29.2.346-354.1991	1991
	Rapid detection of Mycobacterium avium in stool samples from AIDS patients by immunomagnetic PCR.	Li Z, Bai GH, von Reyn CF, Marino P, Brennan MJ, Gine N, Morris SL.	J Clin Microbiol	10.1128/jcm.34.8.1903-1907.1996	1996
	Enhancement of the lethal effects of endotoxins by interferon inducers.	Huang KY, Landay ME.	J Bacteriol	10.1128/jb.100.2.1110-1111.1969	1969
Pathogenicity	Dual-probe assay for rapid detection of drug-resistant Mycobacterium tuberculosis by real-time PCR.	Wada T, Maeda S, Tamaru A, Imai S, Hase A, Kobayashi K.	J Clin Microbiol	10.1128/jcm.42.11.5277-5285.2004	2004
	Genotypic variation and stability of four variable-number tandem repeats and their suitability for discriminating strains of Mycobacterium leprae.	Truman R, Fontes AB, De Miranda AB, Suffys P, Gillis T.	J Clin Microbiol	10.1128/jcm.42.6.2558-2565.2004	2004
Phylogeny	Mycolic acid analysis by high-performance liquid chromatography for identification of Mycobacterium species.	Butler WR, Guthertz LS.	Clin Microbiol Rev	10.1128/cmr.14.4.704-726.2001	2001
Phylogeny	16S ribosomal DNA amplification for phylogenetic study.	Weisburg WG, Barns SM, Pelletier DA, Lane DJ.	J Bacteriol	10.1128/jb.173.2.697-703.1991	1991
Enzymology	The superoxide dismutase gene, a target for detection and identification of mycobacteria by PCR.	Zolg JW, Philippi-Schulz S.	J Clin Microbiol	10.1128/jcm.32.11.2801-2812.1994	1994
Enzymology	Cloning of Mycobacterium bovis BCG DNA and expression of antigens in Escherichia coli.	Thole JE, Dauwerse HG, Das PK, Groothuis DG, Schouls LM, van Embden JD.	Infect Immun	10.1128/iai.50.3.800-806.1985	1985
	Compilation of small ribosomal subunit RNA structures.	Neefs JM, Van de Peer Y, De Rijk P, Chapelle S, De Wachter R.	Nucleic Acids Res	10.1093/nar/21.13.3025	1993
	Mycobacterium.	Barksdale L, Kim KS.	Bacteriol Rev	10.1128/br.41.1.217-372.1977	1977
	Corynebacterium diphtheriae and its relatives.	Barksdale L.	Bacteriol Rev	10.1128/br.34.4.378-422.1970	1970
	Comparative studies of antigen 21 in Mycobacterium and Nocardia species: possible taxonomic relationships with Mycobacterium leprae.	Wideback K, Kronvall G, Bjorvatn B, Closs O, Harboe M.	Infect Immun	10.1128/iai.30.2.413-420.1980	1980
Enzymology	Hydrolyzable tannins (ellagitannins), flavonoids, pentacyclic triterpenes and their glycosides in antimycobacterial extracts of the ethnopharmacologically selected Sudanese medicinal plant Combretum hartmannianum Schweinf.	Salih EYA, Julkunen-Tiitto R, Luukkanen O, Fahmi MKM, Fyhrquist P	Biomed Pharmacother	10.1016/j.biopha.2021.112264	2021
Pathogenicity	Terminalia laxiflora and Terminalia brownii contain a broad spectrum of antimycobacterial compounds including ellagitannins, ellagic acid derivatives, triterpenes, fatty acids and fatty alcohols.	Salih EYA, Julkunen-Tiitto R, Lampi AM, Kanninen M, Luukkanen O, Sipi M, Lehtonen M, Vuorela H, Fyhrquist P	J Ethnopharmacol	10.1016/j.jep.2018.04.030	2018
Pathogenicity	Antimicrobial Diterpenes from Azorella Species Against Gram-Positive Bacteria.	Donoso V, Bacho M, Nuinez S, Rovirosa J, San-Martin A, Leiva S	Nat Prod Commun		2015
Pathogenicity	Molecular Docking Studies of the Antitumoral Activity and Characterization of New Chalcone.	San-Martin A, Donoso V, Leiva S, Bacho M, Nunez S, Gutierrez M, Rovirosa J, Bailon-Moscoso N, Camacho SC, Aviles OM, Cazar ME	Curr Top Med Chem	10.2174/1568026615666150427125033	2015
Pathogenicity	Antibacterial activities of plants from Central Africa used traditionally by the Bakola pygmies for treating respiratory and tuberculosis-related symptoms.	Fomogne-Fodjo MC, Van Vuuren S, Ndinteh DT, Krause RW, Olivier DK	J Ethnopharmacol	10.1016/j.jep.2014.04.032	2014
	Biocompatible high performance hyperbranched epoxy/clay nanocomposite as an implantable material.	Barua S, Dutta N, Karmakar S, Chattopadhyay P, Aidew L, Buragohain AK, Karak N	Biomed Mater	10.1088/1748-6041/9/2/025006	2014
Pathogenicity	An antimicrobial evaluation of plants used for the treatment of respiratory infections in rural Maputaland, KwaZulu-Natal, South Africa.	York T, van Vuuren SF, de Wet H	J Ethnopharmacol	10.1016/j.jep.2012.08.038	2012
Pathogenicity	Synthesis of triazole-oxazolidinones via a one-pot reaction and evaluation of their antimicrobial activity.	Demaray JA, Thuener JE, Dawson MN, Sucheck SJ	Bioorg Med Chem Lett	10.1016/j.bmcl.2008.07.087	2008
Pathogenicity	Synthesis of methyl 5-S-alkyl-5-thio-D-arabinofuranosides and evaluation of their antimycobacterial activity.	Sanki AK, Boucau J, Srivastava P, Adams SS, Ronning DR, Sucheck SJ	Bioorg Med Chem	10.1016/j.bmc.2008.03.062	2008
Metabolism	Inositol phosphate capping of the nonreducing termini of lipoarabinomannan from rapidly growing strains of Mycobacterium.	Khoo KH, Dell A, Morris HR, Brennan PJ, Chatterjee D	J Biol Chem	10.1074/jbc.270.21.12380	1995
Metabolism	Calmodulin-like protein and the phospholipids of Mycobacterium smegmatis.	Burra SS, Reddy PH, Falah SM, Venkitasubramanian TA, Murthy PS	FEMS Microbiol Lett	10.1016/0378-1097(91)90593-y	1991
Enzymology	Modulation of arginine decarboxylase activity from Mycobacterium smegmatis. Evidence for pyridoxal-5'-phosphate-mediated conformational changes in the enzyme.	Balasundaram D, Tyagi AK	Eur J Biochem	10.1111/j.1432-1033.1989.tb14934.x	1989
Enzymology	Purification and properties of aspartate transcarbamylase from Mycobacterium smegmatis.	Masood R, Venkitasubramanian TA	Biochim Biophys Acta	10.1016/0167-4838(88)90014-3	1988
Enzymology	Role of various carbon and nitrogen sources in the regulation of enzymes of pyrimidine biosynthesis in Mycobacterium smegmatis TMC 1546.	Masood R, Venkitasubramanian TA	Ann Inst Pasteur Microbiol	10.1016/0769-2609(87)90036-6	1987
Enzymology	Ornithine transcarbamylase from Mycobacterium smegmatis ATCC 14468: purification, properties, and reaction mechanism.	Ahmad S, Bhatnagar RK, Venkitasubramanian TA	Biochem Cell Biol	10.1139/o86-177	1986
Metabolism	Phospholipids and glycerides composition during spheroplasts formation of Mycobacterium smegmatis ATCC 14468.	Murty MV, Venkitasubramanian TA	Z Naturforsch C Biosci	10.1515/znc-1984-9-1016	1984
Metabolism	Turnover of phospholipids and glycerides of spheroplasts of Mycobacterium smegmatis ATCC 14468.	Murty MV, Venkitasubramanian TA	Ann Microbiol (Paris)	10.1016/s0769-2609(84)80022-8	1984
Metabolism	Influence of carbon and nitrogen sources on arginine biosynthesis in Mycobacterium smegmatis ATCC 14468.	Ahmad S, Bhatnagar RK, Venkitasubramanian TA	Ann Microbiol (Paris)	10.1016/s0769-2609(84)80021-6	1984
Metabolism	Growth and macromolecular synthesis of spheroplasts of Mycobacterium smegmatis ATCC 14468.	Murty MV, Venkitasubramanian TA	Ann Microbiol (Paris)		1983
Enzymology	Purification and characterization of the tween-hydrolyzing esterase of Mycobacterium smegmatis.	Tomioka H	J Bacteriol	10.1128/jb.155.3.1249-1259.1983	1983
Metabolism	Mycobacteriocins produced by rapidly growing mycobacteria are Tween-hydrolyzing esterases.	Saito H, Tomioka H, Watanabe T, Yoneyama T	J Bacteriol	10.1128/jb.153.3.1294-1300.1983	1983
Pathogenicity	Effects of a bacteriocin from Mycobacterium smegmatis on BALB/3T3 and simian virus 40-transformed BALB/c mouse cells.	Saito H, Watanabe T	Microbiol Immunol	10.1111/j.1348-0421.1981.tb00002.x	1981
Metabolism	Characterization of binding sites for a bacteriocin produced by Mycobacterium smegmatis.	Watanabe T, Saito H	J Bacteriol	10.1128/jb.144.1.428-431.1980	1980
Pathogenicity	Effect of a bacteriocin produced by Mycobacterium smegmatis on growth of cultured tumor and normal cells.	Saito H, Watanabe T	Cancer Res		1979
Enzymology	Purification, properties, and cytotoxic effect of a bacteriocin from Mycobacterium smegmatis.	Saito H, Watanabe T, Tomioka H	Antimicrob Agents Chemother	10.1128/AAC.15.4.504	1979
Pathogenicity	Interaction between 30 S ribosomal components in a viomycin resistant mutant of Mycobacterium smegmatis.	Mizuguchi Y, Suga K, Yamada T	Microbiol Immunol	10.1111/j.1348-0421.1979.tb00500.x	1979

References

#10921	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 43277
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Mycobacterium smegmatis (DSM 43277, ATCC 101, ATCC 14468)

Name and taxonomic classification

Morphology

Culture and growth conditions

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Physiology and metabolism

Isolation, sampling and environmental information

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16S sequences

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