Stenotrophomonas maltophilia 560 is an aerobe, mesophilic human pathogen that has multiple antibiotic resistances and was isolated from spinal fluid.
antibiotic resistance aerobe mesophilic human pathogen genome sequence| @ref 20215 |
Last LPSN update
2025-12-16 09:51:07 |
| Domain Pseudomonadati |
| Phylum Pseudomonadota |
| Class Gammaproteobacteria |
| Order Lysobacterales |
| Family Lysobacteraceae |
| Genus Stenotrophomonas |
| Species Stenotrophomonas maltophilia |
| Full scientific name Stenotrophomonas maltophilia (Hugh 1981 ex Hugh and Ryschenkow 1961) Palleroni and Bradbury 1993 |
| Synonyms (3) |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 17812 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | Medium recipe at MediaDive  | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base | ||
| 17812 | TRYPTICASE SOY BROTH AGAR (DSMZ Medium 535) | Medium recipe at MediaDive | Name: TRYPTICASE SOY BROTH AGAR (DSMZ Medium 535) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Distilled water | ||
| 17812 | NUTRIENT AGAR (DSMZ Medium 1) | Medium recipe at MediaDive | Name: NUTRIENT AGAR (DSMZ Medium 1) Composition: Agar 15.0 g/l Peptone 5.0 g/l Meat extract 3.0 g/l Distilled water |
| Test 1 | Test 2 | Test 3 | Test 4 | |
|---|---|---|---|---|
| @ref | 17812 | 17812 | 17812 | 17812 |
| Medium | Mueller-Hinton Agar | Mueller-Hinton Agar | Mueller-Hinton Agar | Mueller-Hinton Agar |
| Incubation temperature | 30 | 30 | 30 | |
| Oxygen condition | aerob | aerob | aerob | |
| Manual_annotation | 1 | 1 | 1 | 1 |
| Inhibition zone diameter in mm | Inhibition zone diameter in mm | Inhibition zone diameter in mm | Inhibition zone diameter in mm | |
| Penicillin G | 20 | 20 | 20 | 20 |
| Oxacillin | 0 | 0 | 0 | 0 |
| Ampicillin | 24-26 | 26 | 26 | 26 |
| Ticarcillin | 34 | 36 | 36-38 | 36-38 |
| Mezlocillin | 22-24 | 26 | 22-24 | 22-24 |
| Cefalotin | 10-12 | 10 | 8 | 8 |
| Cefazolin | 10 | 8-10 | 0 | 0 |
| Cefotaxime | 24-26 | 28 | 28 | 28 |
| Aztreonam | 24 | 26 | 26 | 26 |
| Imipenem | 12 | 10 | 10 | 10 |
| Tetracycline | 16 | 14 | 14 | 14 |
| Chloramphenicol | 22-24 | 30 | 22 | 22 |
| Gentamycin | 8 | 10 | 0 | 0 |
| Amikacin | 6 | 8 | 0 | 0 |
| Vancomycin | 6-8 | 8 | 0 | 0 |
| Erythromycin | 8-10 | 8 | 10 | 10 |
| Lincomycin | 0 | 0 | 0 | 0 |
| Ofloxacin | 24 | 28 | 26 | 26 |
| Norfloxacin | 14 | 14 | 20 | 20 |
| Colistin | 12-14 | 12 | 10-12 | 10-12 |
| Pipemidic acid | 10-12 | 12 | 10 | 10 |
| Nitrofurantoin | 6 | 0 | 0 | 0 |
| Bacitracin | 10-12 | 10 | 10-12 | 10-12 |
| Polymyxin b | 14 | 14 | 12-14 | 12-14 |
| Kanamycin | 8 | 10-12 | 8-10 | 8-10 |
| Neomycin | 0 | 8 | 0 | 0 |
| Doxycycline | 18-20 | 20-22 | 20 | 20 |
| Ceftriaxone | 22 | 22 | 22 | 22 |
| Clindamycin | 0 | 0 | 0 | 0 |
| Fosfomycin | 6-8 | 8 | 8 | 8 |
| Moxifloxacin | 32-34 | 36 | 36-38 | 36-38 |
| Linezolid | 8 | 0 | 6 | 6 |
| Nystatin | 0 | 0 | 0 | 0 |
| Quinupristin/dalfopristin | 8 | 0 | 6 | 6 |
| Teicoplanin | 6 | 0 | 0 | 0 |
| Piperacillin/tazobactam | 22 | 22-24 | 24-26 | 24-26 |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68368 | 27613 ChEBI | amygdalin | - | fermentation | from API 20E |
| 68368 | 29016 ChEBI | arginine | - | hydrolysis | from API 20E |
| 68368 | 16947 ChEBI | citrate | + | assimilation | from API 20E |
| 68368 | 17634 ChEBI | D-glucose | - | fermentation | from API 20E |
| 68368 | 16899 ChEBI | D-mannitol | - | fermentation | from API 20E |
| 68368 | 5291 ChEBI | gelatin | + | hydrolysis | from API 20E |
| 68368 | 30849 ChEBI | L-arabinose | - | fermentation | from API 20E |
| 68368 | 62345 ChEBI | L-rhamnose | - | fermentation | from API 20E |
| 68368 | 25094 ChEBI | lysine | - | degradation | from API 20E |
| 68368 | 28053 ChEBI | melibiose | - | fermentation | from API 20E |
| 68368 | 17268 ChEBI | myo-inositol | - | fermentation | from API 20E |
| 68368 | 18257 ChEBI | ornithine | - | degradation | from API 20E |
| 68368 | 30911 ChEBI | sorbitol | - | fermentation | from API 20E |
| 68368 | 17992 ChEBI | sucrose | - | fermentation | from API 20E |
| 68368 | 27897 ChEBI | tryptophan | - | energy source | from API 20E |
| 68368 | 16199 ChEBI | urea | - | hydrolysis | from API 20E |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68368 | arginine dihydrolase | - | 3.5.3.6 | from API 20E |
| 68368 | beta-galactosidase | + | 3.2.1.23 | from API 20E |
| 68368 | cytochrome oxidase | - | 1.9.3.1 | from API 20E |
| 68368 | gelatinase | + | from API 20E | |
| 68368 | lysine decarboxylase | - | 4.1.1.18 | from API 20E |
| 68368 | ornithine decarboxylase | - | 4.1.1.17 | from API 20E |
| 68368 | tryptophan deaminase | - | 4.1.99.1 | from API 20E |
| 68368 | urease | - | 3.5.1.5 | from API 20E |
| @ref | ONPG | ADH (Arg) | LDC (Lys) | ODC | CIT | H2S productionH2S | URE | TDA (Trp) | IND | Acetoin production (Voges Proskauer test)VP | GEL | GLU | MAN | INO | Sor | RHA | SAC | MEL | AMY | ARA | OX | Nitrite productionNO2 | Reduction to N2N2 | MotilityMOB | Growth on MacConkey mediumMAC | OF-O | OF-F | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 17812 | + | - | - | - | + | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 66792 | 44087_C01 assembly for Stenotrophomonas maltophilia NCTC10258 | complete | GCA_900475405   | 40324.969  | 2847471704  | 40324 | 99.48 | |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Species Interaction and Selective Carbon Addition During Antibiotic Exposure Enhances Bacterial Survival. | Jackson LMD, Kroukamp O, Yeung WC, Ronan E, Liss SN, Wolfaardt GM. | Front Microbiol | 10.3389/fmicb.2019.02730 | 2019 | | |
| Bactericidal Activity of Ceragenin in Combination with Ceftazidime, Levofloxacin, Co-Trimoxazole, and Colistin against the Opportunistic Pathogen Stenotrophomonas maltophilia. | Paprocka P, Mankowska A, Sklodowski K, Krol G, Wollny T, Lesiak A, Gluszek K, Savage PB, Durnas B, Bucki R. | Pathogens | 10.3390/pathogens11060621 | 2022 | | |
| Differentiation of Cystic Fibrosis-Related Pathogens by Volatile Organic Compound Analysis with Secondary Electrospray Ionization Mass Spectrometry. | Kaeslin J, Micic S, Weber R, Muller S, Perkins N, Berger C, Zenobi R, Bruderer T, Moeller A. | Metabolites | 10.3390/metabo11110773 | 2021 | | |
| Characterization of a New Mixture of Mono-Rhamnolipids Produced by Pseudomonas gessardii Isolated from Edmonson Point (Antarctica). | Buonocore C, Tedesco P, Vitale GA, Esposito FP, Giugliano R, Monti MC, D'Auria MV, de Pascale D. | Mar Drugs | 10.3390/md18050269 | 2020 | | |
| Phylogeny | A High-Throughput Short Sequence Typing Scheme for Serratia marcescens Pure Culture and Environmental DNA. | Bourdin T, Monnier A, Benoit ME, Bedard E, Prevost M, Quach C, Deziel E, Constant P. | Appl Environ Microbiol | 10.1128/aem.01399-21 | 2021 | |
| Fluoroquinolones' Biological Activities against Laboratory Microbes and Cancer Cell Lines. | Suaifan GARY, Mohammed AAM, Alkhawaja BA. | Molecules | 10.3390/molecules27051658 | 2022 | | |
| Pathogenicity | Synthesis and In Vitro Antimycobacterial and Antibacterial Activity of 8-OMe Ciprofloxacin-Hydrozone/Azole Hybrids. | Xu Z, Zhang S, Feng LS, Li XN, Huang GC, Chai Y, Lv ZS, Guo HY, Liu ML. | Molecules | 10.3390/molecules22071171 | 2017 | |
| Isolation, Structure Elucidation, and First Total Synthesis of Quinomycins K and L, Two New Octadepsipeptides from the Maowei Sea Mangrove-Derived Streptomyces sp. B475. | Lu Q, Wu G, Hao X, Hu X, Cai H, Liu X, You X, Guo H, Sun C. | Mar Drugs | 10.3390/md21030143 | 2023 | | |
| Biotechnology | Advances in the Microbiology of Stenotrophomonas maltophilia. | Brooke JS. | Clin Microbiol Rev | 10.1128/cmr.00030-19 | 2021 | |
| Enzymology | Carbapenemase Detection among Carbapenem-Resistant Glucose-Nonfermenting Gram-Negative Bacilli. | Simner PJ, Opene BNA, Chambers KK, Naumann ME, Carroll KC, Tamma PD. | J Clin Microbiol | 10.1128/jcm.00775-17 | 2017 | |
| Enzymology | Neo-actinomycins A and B, natural actinomycins bearing the 5H-oxazolo[4,5-b]phenoxazine chromophore, from the marine-derived Streptomyces sp. IMB094. | Wang Q, Zhang Y, Wang M, Tan Y, Hu X, He H, Xiao C, You X, Wang Y, Gan M. | Sci Rep | 10.1038/s41598-017-03769-8 | 2017 | |
| Pathogenicity | Validation of Vitek 2 nonfermenting gram-negative cards and Vitek 2 version 4.02 software for identification and antimicrobial susceptibility testing of nonfermenting gram-negative rods from patients with cystic fibrosis. | Otto-Karg I, Jandl S, Muller T, Stirzel B, Frosch M, Hebestreit H, Abele-Horn M. | J Clin Microbiol | 10.1128/jcm.00505-09 | 2009 | |
| Enzymology | Comparison of 11 Phenotypic Assays for Accurate Detection of Carbapenemase-Producing Enterobacteriaceae. | Tamma PD, Opene BN, Gluck A, Chambers KK, Carroll KC, Simner PJ. | J Clin Microbiol | 10.1128/jcm.02338-16 | 2017 | |
| Metabolism | Bovine intestinal bacteria inactivate and degrade ceftiofur and ceftriaxone with multiple beta-lactamases. | Wagner RD, Johnson SJ, Cerniglia CE, Erickson BD. | Antimicrob Agents Chemother | 10.1128/aac.00008-11 | 2011 | |
| Genetics | Screening and comparison of in vitro-induced resistant and clinically resistant Stenotrophomonas maltophilia strains for eravacycline resistance-related genes. | Wu J, Song J, Cui J. | Front Cell Infect Microbiol | 10.3389/fcimb.2025.1632701 | 2025 | |
| Pathogenicity | In vitro activity of telavancin in combination with colistin versus Gram-negative bacterial pathogens. | Hornsey M, Longshaw C, Phee L, Wareham DW. | Antimicrob Agents Chemother | 10.1128/aac.05870-11 | 2012 | |
| Enzymology | Molecular epidemiology of Stenotrophomonas maltophilia isolated from clinical specimens from patients with cystic fibrosis and associated environmental samples. | Denton M, Todd NJ, Kerr KG, Hawkey PM, Littlewood JM. | J Clin Microbiol | 10.1128/jcm.36.7.1953-1958.1998 | 1998 | |
| Enzymology | Stenotrophomonas maltophilia: an emerging global opportunistic pathogen. | Brooke JS. | Clin Microbiol Rev | 10.1128/cmr.00019-11 | 2012 | |
| Enzymology | Distribution in clinical material and identification of Pseudomonas maltophilia. | Holmes B, Lapage SP, Easterling BG. | J Clin Pathol | 10.1136/jcp.32.1.66 | 1979 | |
| Pathogenicity | Synthetic Peptides Derived from Bovine Lactoferricin Exhibit Antimicrobial Activity against E. coli ATCC 11775, S. maltophilia ATCC 13636 and S. enteritidis ATCC 13076. | Huertas Mendez NJ, Vargas Casanova Y, Gomez Chimbi AK, Hernandez E, Leal Castro AL, Melo Diaz JM, Rivera Monroy ZJ, Garcia Castaneda JE | Molecules | 10.3390/molecules22030452 | 2017 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive17554.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
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