Name: Lactobacillus delbrueckii subsp. bulgaricus 14
Creator: BacDive
License: https://creativecommons.org/licenses/by/4.0/

Strain identifier

BacDive ID: 6449

Type strain:

Species: Lactobacillus delbrueckii subsp. bulgaricus

Strain Designation: 14, Lb.14

Culture col. no.: DSM 20081, ATCC 11842, NCDO 1489, WDCM 00102, CCUG 41390, CIP 101027, LMG 6901, IMET 10708, JCM 1002, BCRC 10696, CCM 7190, CCUG 21450, CECT 4005, IAM 12472, IFO 13953, KCTC 3635, LMG 13551, NBRC 13953, NCFB 1489, NCIMB 11778, NCTC 12712, NRIC 1688, VKM B-1923, VTT E-96662

Strain history: CIP <- 1984, DSMZ <- ATCC <- P.A. Hansen: strain Lb14, Lactobacillus bulgaricus <- S. Orla-Jensen: strain 14, Thermobacterium bulgaricum

NCBI tax ID(s): 390333 (strain), 1585 (subspecies)

SI-ID 3281

LMG 6901, ATCC 11842, IAM 12472, IFO 13953, IMET 10708, JCM 1002, LMG 13551, NCFB 1489, NCIMB 11778, CIP 101027, CCUG 21450, NCDO 1489, NCIB 11778, CCRC 10696, CECT 4005, VKM B-1923, LMD 46.76, KCTC 3635, CCUG 41390, NBRC 13953, NCTC 12712, CCM 7190, NCCB 90022, LMD 90.22, NCCB 46076, BCRC 10696, CDBB 793, VTT E-96662, DSM 20081

Other strains from Lactobacillus delbrueckii subsp. bulgaricus

Section

Lactobacillus delbrueckii subsp. bulgaricus 14 is an anaerobe, Gram-positive bacterium that was isolated from bulgarian yoghourt.

Gram-positive
anaerobe
16S sequence
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	14-12-2023 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Bacillota*
	Class	*Bacilli*
	Order	*Lactobacillales*
	Family	*Lactobacillaceae*
	Genus	*Lactobacillus*
	Species	**Lactobacillus delbrueckii subsp. bulgaricus**
	Full Scientific Name (LPSN)	Lactobacillus delbrueckii subsp. bulgaricus (Orla-Jensen 1919) Weiss et al. 1984

	Synonym	Lactobacillus bulgaricus
	Synonym	"Thermobacterium* bulgaricum"*

Information on morphological and physiological properties Morphology

[Ref.: #118884]	Gram stain	positive
[Ref.: #69480]	Gram stain	positive Confidence in %94.326

[Ref.: #118884]	Cell shape	rod-shaped

[Ref.: #118884]	Motility	no
[Ref.: #69480]	Motility	no Confidence in %95.425

[Ref.: #55042]

Incubation period

2 days

Information on culture and growth conditions Culture and growth conditions

[Ref.: #8508]

Culture medium

MRS MEDIUM (DSMZ Medium 11)

[Ref.: #8508]

Culture medium growth

[Ref.: #8508]

Culture medium link

Medium recipe at MediaDive

[Ref.: #8508]

Culture medium composition

expand / minimize

[Ref.: #41834]

Culture medium

MEDIUM 40- for Lactobacillus and Leuconostoc

[Ref.: #41834]

Culture medium growth

[Ref.: #41834]

Culture medium composition

expand / minimize

[Ref.: #8508]

Culture medium

MRS pre-reduced (DSMZ Medium 11b)

[Ref.: #8508]

Culture medium growth

[Ref.: #8508]

Culture medium link

Medium recipe at MediaDive

[Ref.: #8508]

Culture medium composition

expand / minimize

[Ref.: #118884]

Culture medium

CIP Medium 29

[Ref.: #118884]

Culture medium growth

[Ref.: #118884]

Culture medium link

Medium recipe provided by DSMZ

[Ref.: #118884]

Culture medium

CIP Medium 40

[Ref.: #118884]

Culture medium growth

[Ref.: #118884]

Culture medium link

Medium recipe provided by DSMZ

	Kind of temperature		Temperature
[Ref.: #8508]		growth	37 °C
[Ref.: #41834]		growth	37 °C
[Ref.: #67770]		growth	37 °C
[Ref.: #118884]		growth	30-45 °C
[Ref.: #118884]	no	growth	10 °C
[Ref.: #118884]	no	growth	15 °C
[Ref.: #118884]	no	growth	22 °C

Information on physiology and metabolism Physiology and metabolism

[Ref.: #8508]	Oxygen tolerance	anaerobe
[Ref.: #8508]	Oxygen tolerance	microaerophile
[Ref.: #55042]	Oxygen tolerance	anaerobe
[Ref.: #118884]	Oxygen tolerance	facultative anaerobe

[Ref.: #69480]

Ability of spore formation

no Confidence in %96.23

[Ref.: #8508]	Murein short key	A11.31
[Ref.: #8508]	Murein types	A4alpha L-Lys-D-Asp

	Metabolite	Utilization activity	Kind of utilization tested
[Ref.: #68371]	amygdalin ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	arbutin ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	cellobiose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-arabinose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-arabitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-fucose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-galactose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-lyxose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-mannitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-ribose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-sorbitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-tagatose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-xylose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	erythritol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	galactitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	gentiobiose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	gluconate ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	glycerol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	glycogen ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	inulin ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-arabinose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-arabitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-fucose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-rhamnose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-sorbose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-xylose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	lactose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	maltose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	melezitose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	melibiose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	methyl alpha-D-glucopyranoside ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	methyl alpha-D-mannoside ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	methyl beta-D-xylopyranoside ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	myo-inositol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	N-acetylglucosamine ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #118884]	nitrate ChEBI	-	reduction
[Ref.: #118884]	nitrate ChEBI	+	respiration
[Ref.: #118884]	nitrite ChEBI	-	reduction
[Ref.: #68371]	Potassium 2-ketogluconate ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	Potassium 5-ketogluconate ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	raffinose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	ribitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	salicin ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	starch ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	sucrose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	trehalose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	turanose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	xylitol ChEBI	-	builds acid from	* from API 50CH acid
	Only first 10 entries are displayed. Click here to see all.

	Metabolite production	Metabolite	Production
[Ref.: #118884]		indole ChEBI	no

	Physiological tests	Metabolite	Voges-Proskauer-test	Methylred-test
[Ref.: #118884]		acetoin ChEBI	-
[Ref.: #118884]		glucose ChEBI		+

	Enzyme	Enzyme activity	EC number
[Ref.: #68382]	acid phosphatase	+	3.1.3.2	* from API zym
[Ref.: #118884]	alcohol dehydrogenase	-	1.1.1.1
[Ref.: #68382]	alkaline phosphatase	+	3.1.3.1	* from API zym
[Ref.: #68382]	alpha-chymotrypsin	-	3.4.21.1	* from API zym
[Ref.: #68382]	alpha-fucosidase	-	3.2.1.51	* from API zym
[Ref.: #68382]	alpha-galactosidase	-	3.2.1.22	* from API zym
[Ref.: #68382]	alpha-glucosidase	-	3.2.1.20	* from API zym
[Ref.: #68382]	alpha-mannosidase	-	3.2.1.24	* from API zym
[Ref.: #68382]	beta-galactosidase	+	3.2.1.23	* from API zym
[Ref.: #68382]	beta-glucosidase	-	3.2.1.21	* from API zym
[Ref.: #68382]	beta-glucuronidase	-	3.2.1.31	* from API zym
[Ref.: #118884]	catalase	-	1.11.1.6
[Ref.: #68382]	cystine arylamidase	-	3.4.11.3	* from API zym
[Ref.: #68382]	esterase (C 4)	-		* from API zym
[Ref.: #68382]	esterase lipase (C 8)	-		* from API zym
[Ref.: #68382]	leucine arylamidase	+	3.4.11.1	* from API zym
[Ref.: #68382]	lipase (C 14)	-		* from API zym
[Ref.: #118884]	lysine decarboxylase	-	4.1.1.18
[Ref.: #68382]	N-acetyl-beta-glucosaminidase	-	3.2.1.52	* from API zym
[Ref.: #68382]	naphthol-AS-BI-phosphohydrolase	+		* from API zym
[Ref.: #118884]	ornithine decarboxylase	-	4.1.1.17
[Ref.: #118884]	oxidase	-
[Ref.: #68382]	trypsin	-	3.4.21.4	* from API zym
[Ref.: #118884]	urease	-	3.5.1.5
[Ref.: #68382]	valine arylamidase	-		* from API zym
	Only first 10 entries are displayed. Click here to see all.

API® 50CH acid:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	ControlQ	Acid from glycerolGLY	Acid from erythritolERY	Acid from D-arabinoseDARA	Acid from L-arabinoseLARA	Acid from D-riboseRIB	Acid from D-xyloseDXYL	Acid from L-xyloseLXYL	Acid from D-adonitolADO	Acid from methyl beta-D-xylopyranosideMDX	Acid from D-galactoseGAL	Acid from D-glucoseGLU	Acid from D-fructoseFRU	Acid from D-mannoseMNE	Acid from L-sorboseSBE	Acid from L-rhamnoseRHA	Acid from dulcitolDUL	Acid from inositolINO	Acid from D-mannitolMAN	Acid from D-sorbitolSOR	Acid from methyl alpha-D-mannopyranosideMDM	Acid from methyl alpha-D-glucopyranosideMDG	Acid from N-acetyl-glucosamineNAG	Acid from amygdalinAMY	Acid from arbutinARB	Acid from esculinESC	Acid from salicinSAL	Acid from cellobioseCEL	Acid from maltoseMAL	Acid from lactoseLAC	Acid from melibioseMEL	Acid from sucroseSAC	Acid from trehaloseTRE	Acid from inulinINU	Acid from melezitoseMLZ	Acid from raffinoseRAF	Acid from starchAMD	Acid from glycogenGLYG	Acid from xylitolXLT	Acid from gentiobioseGEN	Acid from turanoseTUR	Acid from D-lyxoseLYX	Acid from D-tagatoseTAG	Acid from D-fucoseDFUC	Acid from L-fucoseLFUC	Acid from D-arabitolDARL	Acid from L-arabitolLARL	Acid from gluconateGNT	Acid from 2-Ketogluconate2KG	Acid from 5-Ketogluconate5KG
[Ref.: #8508]	14504	-	-	-	-	-	-	-	-	-	-	-	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
[Ref.: #8508]	14503	-	-	-	-	-	-	-	-	-	-	-	+	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
[Ref.: #8508]	14502	-	-	-	-	-	-	-	-	-	-	-	+	+/-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
[Ref.: #8508]	14501	-	-	-	-	-	-	-	-	-	-	-	+	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
[Ref.: #8508]	14500	-	-	-	-	-	-	-	-	-	-	-	+	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
[Ref.: #8508]	14499	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
[Ref.: #8508]	14498	-	-	-	-	-	-	-	-	-	-	-	+	+	+	-	-	-	-	-	-	-	-	-	-	-	+/-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

API® zym:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Control	2-naphthyl phosphateAlkaline phosphatase	2-naphthyl butyrateEsterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	2-naphthyl myristateLipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	N-benzoyl-DL-arginine-2-naphthylamideTrypsin	N-glutaryl-phenylalanine-2-naphthylamidealpha- Chymotrypsin	2-naphthyl phosphateAcid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	6-Br-2-naphthyl-alphaD-galactpyranosidealpha- Galactosidase	2-naphthyl-betaD-galactpyranosidebeta- Galactosidase	Naphthol-AS-BI-betaD-glucuronidebeta- Glucuronidase	2-naphthyl-alphaD-glucopyranosidealpha- Glucosidase	6-Br-2-naphthyl-betaD-glucopyranosidebeta- Glucosidase	1-naphthyl-N-acetyl-betaD-glucosaminideN-acetyl-beta- glucosaminidase	6-Br-2-naphthyl-alphaD-mannopyranosidealpha- Mannosidase	2-naphthyl-alphaL-fucopyranosidealpha- Fucosidase
[Ref.: #118884]	6660	-	+	-	-	-	+	-	-	-	-	+	+	-	+	-	-	-	-	-	-

	Pathway	Enzyme coverage	Annotated reactions
	Pathway annotation	Computationally determined by
[Ref.: #66794]	cis-vaccenate biosynthesis	100	2 of 2
[Ref.: #66794]	acetate fermentation	100	4 of 4
[Ref.: #66794]	palmitate biosynthesis	100	22 of 22
[Ref.: #66794]	ppGpp biosynthesis	100	4 of 4
[Ref.: #66794]	coenzyme A metabolism	100	4 of 4
[Ref.: #66794]	teichoic acid biosynthesis	100	1 of 1
[Ref.: #66794]	folate polyglutamylation	100	1 of 1
[Ref.: #66794]	CDP-diacylglycerol biosynthesis	100	2 of 2
[Ref.: #66794]	UDP-GlcNAc biosynthesis	100	3 of 3
[Ref.: #66794]	anapleurotic synthesis of oxalacetate	100	1 of 1
[Ref.: #66794]	aspartate and asparagine metabolism	88.89	8 of 9
[Ref.: #66794]	peptidoglycan biosynthesis	86.67	13 of 15
[Ref.: #66794]	methylglyoxal degradation	80	4 of 5
[Ref.: #66794]	threonine metabolism	80	8 of 10
[Ref.: #66794]	purine metabolism	78.72	74 of 94
[Ref.: #66794]	phenylalanine metabolism	76.92	10 of 13
[Ref.: #66794]	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	75	6 of 8
[Ref.: #66794]	cardiolipin biosynthesis	71.43	5 of 7
[Ref.: #66794]	glycolysis	70.59	12 of 17
[Ref.: #66794]	formaldehyde oxidation	66.67	2 of 3
[Ref.: #66794]	pyrimidine metabolism	66.67	30 of 45
[Ref.: #66794]	acetoin degradation	66.67	2 of 3
[Ref.: #66794]	L-lactaldehyde degradation	66.67	2 of 3
[Ref.: #66794]	cyanate degradation	66.67	2 of 3
[Ref.: #66794]	photosynthesis	64.29	9 of 14
[Ref.: #66794]	cellulose degradation	60	3 of 5
[Ref.: #66794]	valine metabolism	55.56	5 of 9
[Ref.: #66794]	serine metabolism	55.56	5 of 9
[Ref.: #66794]	NAD metabolism	55.56	10 of 18
[Ref.: #66794]	pentose phosphate pathway	54.55	6 of 11
[Ref.: #66794]	methionine metabolism	53.85	14 of 26
[Ref.: #66794]	oxidative phosphorylation	50.55	46 of 91
[Ref.: #66794]	isoleucine metabolism	50	4 of 8
[Ref.: #66794]	ethanol fermentation	50	1 of 2
[Ref.: #66794]	sphingosine metabolism	50	3 of 6
[Ref.: #66794]	butanoate fermentation	50	2 of 4
[Ref.: #66794]	cysteine metabolism	50	9 of 18
[Ref.: #66794]	ketogluconate metabolism	50	4 of 8
[Ref.: #66794]	C4 and CAM-carbon fixation	50	4 of 8
[Ref.: #66794]	sulfopterin metabolism	50	2 of 4
[Ref.: #66794]	phenylmercury acetate degradation	50	1 of 2
[Ref.: #66794]	glycolate and glyoxylate degradation	50	3 of 6
[Ref.: #66794]	CO2 fixation in Crenarchaeota	44.44	4 of 9
[Ref.: #66794]	chorismate metabolism	44.44	4 of 9
[Ref.: #66794]	d-mannose degradation	44.44	4 of 9
[Ref.: #66794]	mevalonate metabolism	42.86	3 of 7
[Ref.: #66794]	propanol degradation	42.86	3 of 7
[Ref.: #66794]	tetrahydrofolate metabolism	42.86	6 of 14
[Ref.: #66794]	glutamate and glutamine metabolism	42.86	12 of 28
[Ref.: #66794]	non-pathway related	42.11	16 of 38
[Ref.: #66794]	metabolism of amino sugars and derivatives	40	2 of 5
[Ref.: #66794]	glycogen metabolism	40	2 of 5
[Ref.: #66794]	glycine metabolism	40	4 of 10
[Ref.: #66794]	arachidonate biosynthesis	40	2 of 5
[Ref.: #66794]	vitamin B1 metabolism	38.46	5 of 13
[Ref.: #66794]	gluconeogenesis	37.5	3 of 8
[Ref.: #66794]	octane oxidation	33.33	1 of 3
[Ref.: #66794]	degradation of aromatic, nitrogen containing compounds	33.33	4 of 12
[Ref.: #66794]	selenocysteine biosynthesis	33.33	2 of 6
[Ref.: #66794]	lipid A biosynthesis	33.33	3 of 9
[Ref.: #66794]	flavin biosynthesis	33.33	5 of 15
[Ref.: #66794]	IAA biosynthesis	33.33	1 of 3
[Ref.: #66794]	acetyl CoA biosynthesis	33.33	1 of 3
[Ref.: #66794]	alanine metabolism	31.03	9 of 29
[Ref.: #66794]	leucine metabolism	30.77	4 of 13
[Ref.: #66794]	starch degradation	30	3 of 10
[Ref.: #66794]	propionate fermentation	30	3 of 10
[Ref.: #66794]	arginine metabolism	29.17	7 of 24
[Ref.: #66794]	lipid metabolism	29.03	9 of 31
[Ref.: #66794]	tryptophan metabolism	28.95	11 of 38
[Ref.: #66794]	tyrosine metabolism	28.57	4 of 14
[Ref.: #66794]	reductive acetyl coenzyme A pathway	28.57	2 of 7
[Ref.: #66794]	citric acid cycle	28.57	4 of 14
[Ref.: #66794]	degradation of hexoses	27.78	5 of 18
[Ref.: #66794]	histidine metabolism	27.59	8 of 29
[Ref.: #66794]	dolichyl-diphosphooligosaccharide biosynthesis	27.27	3 of 11
[Ref.: #66794]	proline metabolism	27.27	3 of 11
[Ref.: #66794]	metabolism of disaccharids	27.27	3 of 11
[Ref.: #66794]	polyamine pathway	26.09	6 of 23
[Ref.: #66794]	dTDPLrhamnose biosynthesis	25	2 of 8
[Ref.: #66794]	lactate fermentation	25	1 of 4
[Ref.: #66794]	cyclohexanol degradation	25	1 of 4
[Ref.: #66794]	degradation of sugar alcohols	25	4 of 16
[Ref.: #66794]	glycogen biosynthesis	25	1 of 4
[Ref.: #66794]	degradation of pentoses	25	7 of 28
[Ref.: #66794]	urea cycle	23.08	3 of 13
[Ref.: #66794]	sulfate reduction	23.08	3 of 13
[Ref.: #66794]	nitrate assimilation	22.22	2 of 9
[Ref.: #66794]	lysine metabolism	21.43	9 of 42
[Ref.: #66794]	glutathione metabolism	21.43	3 of 14
[Ref.: #66794]	vitamin B12 metabolism	20.59	7 of 34
		Only first 10 entries are displayed. Click here to see all.

Information on isolation source, the sampling and environmental conditions Isolation, sampling and environmental information

[Ref.: #8508]	Sample type/isolated from	bulgarian yoghourt

[Ref.: #55042]	Sample type/isolated from	Bulgarian yogurt

[Ref.: #67770]	Sample type/isolated from	Bulgarian yogurt

[Ref.: #118884]	Sample type/isolated from	Food, Bulgarian yogurt
* marker position based on {}

Isolation sources categories

#Engineered

#Food production

#Dairy product

What are isolation sources categories?

[Ref.: #69479]

Global distribution of 16S sequence KC429786 (>99% sequence identity) for Lactobacillus delbrueckii from Microbeatlas

Aquatic Samples	6667
Soil Samples	2030
Animal Samples	50988
Plant Samples	973
Total Samples	60658

Information on possible application of the strain and its possible interaction with e.g. potential hosts Safety information

[Ref.: #8508]	Biosafety level	1	Risk group (German classification) According to TRBA 466
[Ref.: #118884]	Biosafety level	1	Risk group (French classification)

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

16S Sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence accession description	Seq. accession number	Sequence length (bp)	Sequence database	Associated NCBI tax ID
[Ref.: #67770]	Lactobacillus delbrueckii subsp. bulgaricus gene for 16S ribosomal RNA, partial sequence, strain: JCM 1002	LC063162	1525	GenBank ENA	1585 tax ID
[Ref.: #20218]	Lactobacillus delbrueckii subsp. bulgaricus 16S-23S ribosomal RNA intergenic spacer region, complete sequence	AF113602	220	GenBank ENA	390333 tax ID	*
[Ref.: #20218]	Lactobacillus delbrueckii subsp. bulgaris ATCC 11842 16S ribosomal RNA gene, partial sequence	AF429503	502	GenBank ENA	390333 tax ID	*
[Ref.: #20218]	Lactobacillus delbrueckii subsp. bulgaricus strain ATCC 11842 16S ribosomal RNA gene, partial sequence; 16S-23S intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence	AF429590	536	GenBank ENA	390333 tax ID	*
[Ref.: #20218]	Lactobacillus delbrueckii subsp. bulgaricus partial 16S rRNA gene, strain ATCC 11842	AJ414693	535	GenBank ENA	390333 tax ID	*
[Ref.: #124043]	Lactobacillus delbrueckii subsp. bulgaricus JCM1002 gene for 16S rRNA, partial sequence.	LC685623	1435	GenBank ENA	1585 tax ID	*
[Ref.: #20218]	Lactobacillus delbrueckii subsp. bulgaricus 16S ribosomal RNA gene, partial sequence	AY050171	1513	GenBank ENA	390333 tax ID	*
[Ref.: #20218]	Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 16S ribosomal RNA gene, partial sequence	KC429786	1423	GenBank ENA	390333 tax ID	*
[Ref.: #20218]	L.bulgaricus rrn operon, 16S-23S rRNA spacer (long), tRNA-Ile and tRNA-Ala genes	Z75475	455	GenBank ENA	390333 tax ID	*
[Ref.: #20218]	L.bulgaricus rrn operon, 16S-23S rRNA spacer (short)	Z75476	217	GenBank ENA	390333 tax ID	*
[Ref.: #20218]	Lactobacillus delbrueckii subsp. bulgaricus strain BCRC10696 16S ribosomal RNA gene, complete sequence	AY773948	1494	GenBank ENA	1585 tax ID	*
[Ref.: #20218]	Lactobacillus delbrueckii subsp. bulgaricus partial 16S rRNA gene, type strain ATCC 11842T	FR683102	1475	GenBank ENA	1585 tax ID	*
[Ref.: #20218]	Lactobacillus delbrueckii 16S rRNA gene from I-CeuI fragment 1, strain DSM20081	AJ010835	436	GenBank ENA	1584 tax ID	*
[Ref.: #20218]	Lactobacillus delbrueckii bulgaricus (strain DSM20081) 16S rRNA gene, partial	AJ010983	436	GenBank ENA	1584 tax ID	*
[Ref.: #20218]	Lactobacillus delbrueckii gene for 16S rRNA, partial sequence	AB007908	1516	GenBank ENA	1584 tax ID	*
[Ref.: #20218]	Lactobacillus delbrueckii gene, 16S-23S rRNA intergenic spacer region and 23S rRNA gene 5' flanking region, partial sequence	AB035485	671	GenBank ENA	1584 tax ID	*
[Ref.: #20218]	Lactobacillus delbrueckii subsp. bulgaricus gene for 16S rRNA, partial sequence, strain: JCM 1002	AB289080	675	GenBank ENA	1585 tax ID	*
[Ref.: #20218]	Lactobacillus delbrueckii subsp. bulgaricus gene for 16S rRNA, partial sequence, strain: NBRC 13953	AB680531	1489	GenBank ENA	1585 tax ID	*

Genome sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence accession description	Seq. accession number	Assembly level	Sequence database	Associated NCBI tax ID
[Ref.: #67770]	Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002	GCA_001311275	contig	GenBank ENA	390333 tax ID
[Ref.: #67770]	Lactobacillus delbrueckii subsp. bulgaricus NBRC 13953	GCA_006539405	contig	GenBank ENA	1585 tax ID
[Ref.: #67770]	Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002 DSM 20081	GCA_001437195	scaffold	GenBank ENA	390333 tax ID
[Ref.: #66792]	Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002	390333.12	wgs	PATRIC	390333 tax ID	*
[Ref.: #66792]	Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002 DSM 20081	GCA_029823585	scaffold	GenBank ENA	390333 tax ID	*
[Ref.: #66792]	Lactobacillus delbrueckii bulgaricus JCM 1002	2728369678	draft	JGI IMG/M	390333 tax ID	*

[Ref.: #8508]	GC-content	50.3 mol%
[Ref.: #67770]	GC-content	49.9 mol%	genome sequence analysis

Data predicted using genome information as a basis Genome-based predictions

	Trait	Prediction	Confidence in %	In training data
	Predictions from GenomeNet Sporulation v. 1 based on: Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002 ATCC 11842 NCBI: GCA_000056065.1
[Ref.: #69481]	spore-forming	no	87	no

	Trait	Prediction	Confidence in %	In training data
	Predictions from Diaspora project based on: Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002 ATCC 11842 NCBI: GCA_000056065.1
[Ref.: #69480]	motile	no	95.425	no
[Ref.: #69480]	flagellated	no	98.086	no
[Ref.: #69480]	gram-positive	yes	94.326	no
[Ref.: #69480]	anaerobic	yes	56.149	no
[Ref.: #69480]	aerobic	no	97.429	no
[Ref.: #69480]	halophile	yes	84.093	no
[Ref.: #69480]	spore-forming	no	96.23	no
[Ref.: #69480]	thermophile	no	99.269	yes
[Ref.: #69480]	glucose-util	yes	93.375	no
[Ref.: #69480]	glucose-ferment	yes	90.13	no

Availability in culture collections External links

[Ref.: #8508]

Culture collection no.

DSM 20081, ATCC 11842, NCDO 1489, WDCM 00102, CCUG 41390, CIP 101027, LMG 6901, IMET 10708, JCM 1002, BCRC 10696, CCM 7190, CCUG 21450, CECT 4005, IAM 12472, IFO 13953, KCTC 3635, LMG 13551, NBRC 13953, NCFB 1489, NCIMB 11778, NCTC 12712, NRIC 1688, VKM B-1923, VTT E-96662

[Ref.: #75922]

SI-ID 3281

Literature:

Only first 10 entries are displayed. Click here to see all.

	Title	Authors	Journal	DOI	Year
Pathogenicity	Global transcriptomic analysis of Lactobacillus delbrueckii subsp. bulgaricus ATCC11842 reveals the role of LDB_RS05285 in the post-acidification of yogurt.	Zhang S, Li D, Zhang X, Sun Y, Xu S, Wang X, Zhang N, Wang M, Tian H, Li C	Food Funct	10.1039/d1fo01357b	2021	*
Genetics	Whole-genome sequencing and genomic-based acid tolerance mechanisms of Lactobacillus delbrueckii subsp. bulgaricus LJJ.	Li W, Yang L, Nan W, Lu J, Zhang S, Ujiroghene OJ, Pang X, Lv J	Appl Microbiol Biotechnol	10.1007/s00253-020-10788-5	2020	*
Metabolism	Effects of ccpA gene deficiency in Lactobacillus delbrueckii subsp. bulgaricus under aerobic conditions as assessed by proteomic analysis.	Zhang G, Liu L, Li C	Microb Cell Fact	10.1186/s12934-020-1278-7	2020	*
Metabolism	A selective medium for the enumeration and differentiation of Lactobacillus delbrueckii ssp. bulgaricus.	Nwamaioha NO, Ibrahim SA	J Dairy Sci	10.3168/jds.2017-14155	2018	*
Metabolism	Formation of tyramine in yoghurt during fermentation - Interaction between yoghurt starter bacteria and Lactobacillus plantarum.	Yilmaz C, Gokmen V	Food Res Int	10.1016/j.foodres.2017.04.014	2017	*
Metabolism	Transferase Activity of Lactobacillal and Bifidobacterial beta-Galactosidases with Various Sugars as Galactosyl Acceptors.	Arreola SL, Intanon M, Wongputtisin P, Kosma P, Haltrich D, Nguyen TH	J Agric Food Chem	10.1021/acs.jafc.5b06009	2016	*
Metabolism	Catabolite responsive element deficiency of xyl operon resulting in carbon catabolite derepression in Lactobacillus fermentum 1001.	Zhang C, Guo T, Xin Y, Gao X, Kong J	J Appl Microbiol	10.1111/jam.12990	2015	*
Biotechnology	Enhancing the light-driven production of D-lactate by engineering cyanobacterium using a combinational strategy.	Li C, Tao F, Ni J, Wang Y, Yao F, Xu P	Sci Rep	10.1038/srep09777	2015	*
Metabolism	Lactobacillus gasseri SBT2055 suppresses fatty acid release through enlargement of fat emulsion size in vitro and promotes fecal fat excretion in healthy Japanese subjects.	Ogawa A, Kobayashi T, Sakai F, Kadooka Y, Kawasaki Y	Lipids Health Dis	10.1186/s12944-015-0019-0	2015	*
Enzymology	Major Role of NAD-Dependent Lactate Dehydrogenases in the Production of l-Lactic Acid with High Optical Purity by the Thermophile Bacillus coagulans.	Wang L, Cai Y, Zhu L, Guo H, Yu B	Appl Environ Microbiol	10.1128/AEM.01864-14	2014	*
Metabolism	Phosphorylation of uridine and cytidine by uridine-cytidine kinase.	Qian Y, Ding Q, Li Y, Zou Z, Yan B, Ou L	J Biotechnol	10.1016/j.jbiotec.2014.08.018	2014	*
Enzymology	Efficient production of (R)-2-hydroxy-4-phenylbutyric acid by using a coupled reconstructed D-lactate dehydrogenase and formate dehydrogenase system.	Sheng B, Zheng Z, Lv M, Zhang H, Qin T, Gao C, Ma C, Xu P	PLoS One	10.1371/journal.pone.0104204	2014	*
Metabolism	Proteomic analysis of the response to NaCl stress of Lactobacillus bulgaricus.	Li C, Li PZ, Sun JW, Huo GC, Liu LB	Biotechnol Lett	10.1007/s10529-014-1601-7	2014	*
Metabolism	Highly stereoselective biosynthesis of (R)-alpha-hydroxy carboxylic acids through rationally re-designed mutation of D-lactate dehydrogenase.	Zheng Z, Sheng B, Gao C, Zhang H, Qin T, Ma C, Xu P	Sci Rep	10.1038/srep03401	2013	*
Phylogeny	Isolation and characterization of bacteriocin-producing bacteria from the intestinal microbiota of elderly Irish subjects.	Lakshminarayanan B, Guinane CM, O'Connor PM, Coakley M, Hill C, Stanton C, O'Toole PW, Ross RP	J Appl Microbiol	10.1111/jam.12085	2012	*
Metabolism	Growth advantage of Streptococcus thermophilus over Lactobacillus bulgaricus in vitro and in the gastrointestinal tract of gnotobiotic rats.	Ben-Yahia L, Mayeur C, Rul F, Thomas M	Benef Microbes	10.3920/BM2012.0012	2012	*
Biotechnology	In vivo study of the survival of Lactobacillus delbruecki subsp. bulgaricus CECT 4005T and Streptococcus thermophilus CECT 801 by DVC-FISH after consumption of fermented milk.	Garcia-Hernandez J, Moreno Y, Chuan C, Hernandez M	J Food Sci	10.1111/j.1750-3841.2012.02918.x	2012	*
Enzymology	Homodimeric beta-galactosidase from Lactobacillus delbrueckii subsp. bulgaricus DSM 20081: expression in Lactobacillus plantarum and biochemical characterization.	Nguyen TT, Nguyen HA, Arreola SL, Mlynek G, Djinovic-Carugo K, Mathiesen G, Nguyen TH, Haltrich D	J Agric Food Chem	10.1021/jf203909e	2012	*
Metabolism	Characterization of the cysK2-ctl1-cysE2 gene cluster involved in sulfur metabolism in Lactobacillus casei.	Bogicevic B, Irmler S, Portmann R, Meile L, Berthoud H	Int J Food Microbiol	10.1016/j.ijfoodmicro.2011.06.015	2011	*
Metabolism	Cholesterol removal by some lactic acid bacteria that can be used as probiotic.	Tok E, Aslim B	Microbiol Immunol	10.1111/j.1348-0421.2010.00219.x	2010	*
Enzymology	Exploring the acidotolerance of beta-galactosidase from Lactobacillus delbrueckii subsp. bulgaricus: an attractive enzyme for lactose bioconversion.	Rhimi M, Aghajari N, Jaouadi B, Juy M, Boudebbouze S, Maguin E, Haser R, Bejar S	Res Microbiol	10.1016/j.resmic.2009.09.004	2009	*
Metabolism	Postgenomic analysis of streptococcus thermophilus cocultivated in milk with Lactobacillus delbrueckii subsp. bulgaricus: involvement of nitrogen, purine, and iron metabolism.	Herve-Jimenez L, Guillouard I, Guedon E, Boudebbouze S, Hols P, Monnet V, Maguin E, Rul F	Appl Environ Microbiol	10.1128/AEM.01984-08	2008	*
Metabolism	Production of a heterologous nonheme catalase by Lactobacillus casei: an efficient tool for removal of H2O2 and protection of Lactobacillus bulgaricus from oxidative stress in milk.	Rochat T, Gratadoux JJ, Gruss A, Corthier G, Maguin E, Langella P, van de Guchte M	Appl Environ Microbiol	10.1128/AEM.00482-06	2006	*
Genetics	Testing of a whole genome PCR scanning approach to identify genomic variability in four different species of lactic acid bacteria.	Ben Zakour N, Grimaldi C, Gautier M, Langella P, Azevedo V, Maguin E, Le Loir Y	Res Microbiol	10.1016/j.resmic.2005.09.006	2005	*
Metabolism	Heterologous expression of lactose- and galactose-utilizing pathways from lactic acid bacteria in Corynebacterium glutamicum for production of lysine in whey.	Barrett E, Stanton C, Zelder O, Fitzgerald G, Ross RP	Appl Environ Microbiol	10.1128/AEM.70.5.2861-2866.2004	2004	*
Biotechnology	Characterization of urease genes cluster of Streptococcus thermophilus.	Mora D, Maguin E, Masiero M, Parini C, Ricci G, Manachini PL, Daffonchio D	J Appl Microbiol	10.1046/j.1365-2672.2003.02148.x	2004	*
Biotechnology	The lactobin A and amylovorin L471 encoding genes are identical, and their distribution seems to be restricted to the species Lactobacillus amylovorus that is of interest for cereal fermentations.	De Vuyst L, Avonts L, Neysens P, Hoste B, Vancanneyt M, Swings J, Callewaert R	Int J Food Microbiol	10.1016/s0168-1605(03)00298-8	2004	*
Enzymology	Isolation of the patC gene encoding the cystathionine beta-lyase of Lactobacillus delbrueckii subsp. bulgaricus and molecular analysis of inter-strain variability in enzyme biosynthesis.	Aubel D, Germond JE, Gilbert C, Atlan D	Microbiology (Reading)	10.1099/00221287-148-7-2029	2002	*
Metabolism	Physiological study of Lactobacillus delbrueckii subsp. bulgaricus strains in a novel chemically defined medium.	Chervaux C, Ehrlich SD, Maguin E	Appl Environ Microbiol	10.1128/AEM.66.12.5306-5311.2000	2000	*
Enzymology	Production, purification and characterization of reutericin 6, a bacteriocin with lytic activity produced by Lactobacillus reuteri LA6.	Kabuki T, Saito T, Kawai Y, Uemura J, Itoh T	Int J Food Microbiol	10.1016/s0168-1605(96)01180-4	1997	*
Genetics	Lactobacillus bulgaricus asparagine synthetase and asparaginyl-tRNA synthetase: coregulation by transcription antitermination?	Kim SI, Germond JE, Pridmore D, Soll D	J Bacteriol	10.1128/jb.178.8.2459-2461.1996	1996	*
Metabolism	Jenseniin G, a heat-stable bacteriocin produced by Propionibacterium jensenii P126.	Grinstead DA, Barefoot SF	Appl Environ Microbiol	10.1128/aem.58.1.215-220.1992	1992	*
Biotechnology	Stability of Lactobacillus bulgaricus immobilized in kappa-carrageenan gels.	Buyukgungor H	J Chem Technol Biotechnol	10.1002/jctb.280530211	1992	*
Phylogeny	Deoxyribonucleic acid hybridization among strains of lactobacilli.	Simonds J, Hansen PA, Lakshmanan S	J Bacteriol	10.1128/jb.107.1.382-384.1971	1971	*
	Insights into lactic acid bacteria cryoresistance using FTIR microspectroscopy.	Girardeau A, Passot S, Meneghel J, Cenard S, Lieben P, Trelea IC, Fonseca F	Anal Bioanal Chem	10.1007/s00216-021-03774-x	2021	*
	Assessment of Ready-to-Use Freeze-dried Immobilized Biocatalysts as Innovative Starter Cultures in Sourdough Bread Making.	Mantzourani I, Terpou A, Alexopoulos A, Bezirtzoglou E, Plessas S	Foods	10.3390/foods8010040	2019	*
	Non-sterilized fermentation of high optically pure D-lactic acid by a genetically modified thermophilic Bacillus coagulans strain.	Zhang C, Zhou C, Assavasirijinda N, Yu B, Wang L, Ma Y	Microb Cell Fact	10.1186/s12934-017-0827-1	2017	*
	Immobilization of beta-Galactosidases from Lactobacillus on Chitin Using a Chitin-Binding Domain.	Pham ML, Leister T, Nguyen HA, Do BC, Pham AT, Haltrich D, Yamabhai M, Nguyen TH, Nguyen TT	J Agric Food Chem	10.1021/acs.jafc.6b04982	2017	*

References

#8508

Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 20081

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#20218

Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )

#41834 ; Curators of the CIP;
#55042 Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 41390

#66792

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#66794

Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )

#67770 Japan Collection of Microorganism (JCM) ; Curators of the JCM;

#68371

Automatically annotated from API 50CH acid .

#68382

Automatically annotated from API zym .

#69479

João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .

#69480

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#69481

Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch: Predictions based on the model GenomeNet Sporulation v. 1 . ( DOI 10.21203/rs.3.rs-2527258/v1 )

#75922

Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.: StrainInfo: A central database for resolving microbial strain identifiers . ( DOI 10.60712/SI-ID3281.1 )

#118884 Collection of Institut Pasteur ; Curators of the CIP; CIP 101027

#124043

Dr. Isabel Schober, Dr. Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .

* These data were automatically processed and therefore are not curated

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Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002 ATCC 11842

Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002 ATCC 11842

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