Ligilactobacillus animalis (DSM 20602, ATCC 35046, NCDO 2425)

Name: Ligilactobacillus animalis (DSM 20602, ATCC 35046, NCDO 2425)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 6416

Type strain

Strain Designation PPI/1535, PP1/1535

Culture col. no. DSM 20602 ATCC 35046 NCDO 2425 CCUG 33906 PPI/1535 15 more

NCBI tax ID(s) 1605

Special Collections DSMZ CCUG JCM KCTC CIP

History <- NCDO <- V.E. Dent, PPI/1535 ATCC 35046 <-- NCDO 2425 <-- R. A. D. Williams 1535. CIP <- 1988, NCFB <- 1981, R.A.D. Williams: strain PP1/1535

Links

Ligilactobacillus animalis PPI/1535 is an anaerobe, Gram-positive, rod-shaped bacterium that was isolated from dental plaque of baboon.

Gram-positive rod-shaped anaerobe genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 13695

LMG 9843,ATCC 35046,CCUG 33906,NCFB 2425,NCDO 2425,CIP 103152,JCM 5670,CCRC 14617,IAM 13547,IFO 15882,NCIMB 13278,CECT 4060,KCTC 3501,NBRC 15882,NRRL B-14176,BCRC 14617,CCT 3755,CGMCC 1.2623,VTT E-991268,DSM 20602

@ref 20215

Last LPSN update 2026-02-09 11:19:12

Domain Bacteria

Phylum Bacillota

Class Bacilli

Order Lactobacillales

Family Lactobacillaceae

Genus Ligilactobacillus

Species Ligilactobacillus animalis

Full scientific name Ligilactobacillus animalis (Dent and Williams 1983) Zheng et al. 2020

Synonyms (1)

Lactobacillus animalis

BacDive ID	Other strains from **Ligilactobacillus animalis** (9)	Type strain
165563	L. animalis JCM 7692
165566	L. animalis JCM 7700
165570	L. animalis JCM 7707
165571	L. animalis JCM 7708
165572	L. animalis JCM 7709
165581	L. animalis JCM 7726
165585	L. animalis JCM 7730
165927	L. animalis JCM 8692
165932	L. animalis JCM 8697

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Motility	Confidence
116392	positive	rod-shaped
125438	positive			92.524

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
8950	MRS MEDIUM (DSMZ Medium 11)	Medium recipe at MediaDive	Name: MRS MEDIUM (DSMZ Medium 11) Composition: Glucose 20.0 g/l Casein peptone 10.0 g/l Meat extract 10.0 g/l Na-acetate 5.0 g/l Yeast extract 5.0 g/l (NH4)3 citrate 2.0 g/l K2HPO4 2.0 g/l Tween 80 1.0 g/l MgSO4 x 7 H2O 0.2 g/l MnSO4 x H2O 0.05 g/l Distilled water
40543	MEDIUM 40- for Lactobacillus and Leuconostoc		Distilled water make up to (1000.000 ml);Man Rogosa Sharp agar (68.000 g)
116392	CIP Medium 40	Medium recipe at CIP
116392	CIP Medium 41	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
8950	positive	growth	37
40543	positive	growth	37
51813	positive	growth	37
67770	positive	growth	37
116392	positive	growth	22-45
116392	negative	growth	10
116392	negative	growth	15

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
8950	anaerobe
8950	microaerophile
51813	anaerobe
51813	microaerophile
116392	facultative anaerobe
125439	microaerophile	99.1

Murein

@ref	Murein short key	Type
8950	A11.31	A4alpha L-Lys-D-Asp

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68371	27613 ChEBI	amygdalin	+	builds acid from	from API 50CH acid
68371	17057 ChEBI	cellobiose	+	builds acid from	from API 50CH acid
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68371	15824 ChEBI	D-fructose	+	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	+	builds acid from	from API 50CH acid
68371	17634 ChEBI	D-glucose	+	builds acid from	from API 50CH acid
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68371	16899 ChEBI	D-mannitol	-	builds acid from	from API 50CH acid
68371	16024 ChEBI	D-mannose	+	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68371	16443 ChEBI	D-tagatose	-	builds acid from	from API 50CH acid
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
68371	4853 ChEBI	esculin	+	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68371	28066 ChEBI	gentiobiose	+	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	-	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68371	30849 ChEBI	L-arabinose	-	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68371	17716 ChEBI	lactose	+	builds acid from	from API 50CH acid
68371	17306 ChEBI	maltose	+	builds acid from	from API 50CH acid
68371	6731 ChEBI	melezitose	-	builds acid from	from API 50CH acid
68371	28053 ChEBI	melibiose	+	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
68371	59640 ChEBI	N-acetylglucosamine	+	builds acid from	from API 50CH acid
116392	17632 ChEBI	nitrate	-	reduction
116392	17632 ChEBI	nitrate	+	respiration
116392	16301 ChEBI	nitrite	-	reduction
68371		Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371		Potassium 5-ketogluconate	-	builds acid from	from API 50CH acid
68371	16634 ChEBI	raffinose	+	builds acid from	from API 50CH acid
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
68371	17814 ChEBI	salicin	+	builds acid from	from API 50CH acid
68371	28017 ChEBI	starch	-	builds acid from	from API 50CH acid
68371	17992 ChEBI	sucrose	+	builds acid from	from API 50CH acid
68371	27082 ChEBI	trehalose	-	builds acid from	from API 50CH acid
68371	32528 ChEBI	turanose	-	builds acid from	from API 50CH acid
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test
116392	15688 ChEBI	acetoin	+

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
116392	alcohol dehydrogenase	-	1.1.1.1
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	+	3.2.1.22	from API zym
68382	alpha-glucosidase	-	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68382	beta-galactosidase	+	3.2.1.23	from API zym
68382	beta-glucosidase	-	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
116392	catalase	-	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	-		from API zym
68382	esterase lipase (C 8)	-		from API zym
68382	leucine arylamidase	-	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
116392	lysine decarboxylase	-	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
116392	ornithine decarboxylase	-	4.1.1.17
116392	oxidase	-
68382	trypsin	-	3.4.21.4	from API zym
68382	valine arylamidase	-		from API zym

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	palmitate biosynthesis	100	22 of 22
66794	ppGpp biosynthesis	100	4 of 4
66794	acetoin degradation	100	3 of 3
66794	cis-vaccenate biosynthesis	100	2 of 2
66794	formaldehyde oxidation	100	3 of 3
66794	UDP-GlcNAc biosynthesis	100	3 of 3
66794	folate polyglutamylation	100	1 of 1
66794	coenzyme A metabolism	100	4 of 4
66794	CDP-diacylglycerol biosynthesis	100	2 of 2
66794	aspartate and asparagine metabolism	88.89	8 of 9
66794	gluconeogenesis	87.5	7 of 8
66794	pentose phosphate pathway	81.82	9 of 11
66794	purine metabolism	80.85	76 of 94
66794	pyrimidine metabolism	80	36 of 45
66794	threonine metabolism	80	8 of 10
66794	peptidoglycan biosynthesis	80	12 of 15
66794	metabolism of amino sugars and derivatives	80	4 of 5
66794	glycogen metabolism	80	4 of 5
66794	glycogen biosynthesis	75	3 of 4
66794	acetate fermentation	75	3 of 4
66794	C4 and CAM-carbon fixation	75	6 of 8
66794	photosynthesis	71.43	10 of 14
66794	cardiolipin biosynthesis	71.43	5 of 7
66794	starch degradation	70	7 of 10
66794	vitamin B1 metabolism	69.23	9 of 13
66794	L-lactaldehyde degradation	66.67	2 of 3
66794	glycolysis	64.71	11 of 17
66794	dTDPLrhamnose biosynthesis	62.5	5 of 8
66794	phenylalanine metabolism	61.54	8 of 13
66794	methylglyoxal degradation	60	3 of 5
66794	methionine metabolism	57.69	15 of 26
66794	propanol degradation	57.14	4 of 7
66794	NAD metabolism	55.56	10 of 18
66794	serine metabolism	55.56	5 of 9
66794	valine metabolism	55.56	5 of 9
66794	non-pathway related	52.63	20 of 38
66794	ketogluconate metabolism	50	4 of 8
66794	isoleucine metabolism	50	4 of 8
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	50	4 of 8
66794	ethanol fermentation	50	1 of 2
66794	butanoate fermentation	50	2 of 4
66794	cysteine metabolism	50	9 of 18
66794	ribulose monophosphate pathway	50	1 of 2
66794	sulfopterin metabolism	50	2 of 4
66794	phenylmercury acetate degradation	50	1 of 2
66794	selenocysteine biosynthesis	50	3 of 6
66794	oxidative phosphorylation	49.45	45 of 91
66794	glutamate and glutamine metabolism	46.43	13 of 28
66794	isoprenoid biosynthesis	46.15	12 of 26
66794	proline metabolism	45.45	5 of 11
66794	alanine metabolism	44.83	13 of 29
66794	CO2 fixation in Crenarchaeota	44.44	4 of 9
66794	d-mannose degradation	44.44	4 of 9
66794	degradation of sugar alcohols	43.75	7 of 16
66794	ubiquinone biosynthesis	42.86	3 of 7
66794	mevalonate metabolism	42.86	3 of 7
66794	glutathione metabolism	42.86	6 of 14
66794	lipid metabolism	41.94	13 of 31
66794	lipoate biosynthesis	40	2 of 5
66794	cellulose degradation	40	2 of 5
66794	arachidonate biosynthesis	40	2 of 5
66794	lysine metabolism	38.1	16 of 42
66794	vitamin B6 metabolism	36.36	4 of 11
66794	metabolism of disaccharids	36.36	4 of 11
66794	tetrahydrofolate metabolism	35.71	5 of 14
66794	degradation of pentoses	35.71	10 of 28
66794	degradation of hexoses	33.33	6 of 18
66794	glycolate and glyoxylate degradation	33.33	2 of 6
66794	arginine metabolism	33.33	8 of 24
66794	degradation of aromatic, nitrogen containing compounds	33.33	4 of 12
66794	acetyl CoA biosynthesis	33.33	1 of 3
66794	cyanate degradation	33.33	1 of 3
66794	lipid A biosynthesis	33.33	3 of 9
66794	flavin biosynthesis	33.33	5 of 15
66794	octane oxidation	33.33	1 of 3
66794	IAA biosynthesis	33.33	1 of 3
66794	sphingosine metabolism	33.33	2 of 6
66794	urea cycle	30.77	4 of 13
66794	glycine metabolism	30	3 of 10
66794	propionate fermentation	30	3 of 10
66794	Entner Doudoroff pathway	30	3 of 10
66794	reductive acetyl coenzyme A pathway	28.57	2 of 7
66794	d-xylose degradation	27.27	3 of 11
66794	polyamine pathway	26.09	6 of 23
66794	cyclohexanol degradation	25	1 of 4
66794	toluene degradation	25	1 of 4
66794	lactate fermentation	25	1 of 4
66794	carnitine metabolism	25	2 of 8
66794	CMP-KDO biosynthesis	25	1 of 4
66794	leucine metabolism	23.08	3 of 13
66794	sulfate reduction	23.08	3 of 13
66794	ascorbate metabolism	22.73	5 of 22
66794	tyrosine metabolism	21.43	3 of 14

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
116392	-	+	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	-	-

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
8950	-	-	-	-	-	+/-	-	-	-	-	+	+	+	+	-	-	-	-	-	-	-	-	+	+	+	+	+	+	+	+	+	+	-	-	-	+	-	-	-	+	-	-	-	-	-	-	-	-	-	-
116392	not determinedn.d.	-	-	-	-	+/-	-	-	-	-	+	+	+	+	-	-	-	-	-	-	-	-	+	+	-	+	+	+	+	+	+	+	-	-	-	+	-	-	-	+	-	-	-	-	-	-	-	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Host	#Mammals	#Primates
#Host Body-Site	#Oral cavity and airways	#Plaque
#Host Body-Site	#Oral cavity and airways	#Tooth

Isolation

@ref	Sample type	Geographic location	Country	Country ISO 3 Code	Continent
8950	dental plaque of baboon
51813	Baboon dental plaque
67770	Dental plaque of baboon
116392	Animal, Baboon, dental plaque	London	United Kingdom	GBR	Europe

Taxonmaps

69479

Global distribution of 16S sequence LC071814 (>99% sequence identity) for Ligilactobacillus from Microbeatlas

Aquatic Samples	383
Soil Samples	571
Animal Samples	37886
Plant Samples	247
Total Samples	39087

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
8950	1	Risk group (German classification) According to TRBA 466
116392	1	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
67770	ASM18382v1 assembly for Ligilactobacillus animalis KCTC 3501 = DSM 20602	scaffold	GCA_000183825	930942.3	651324057	930942	70.4
67770	ASM143453v1 assembly for Ligilactobacillus animalis KCTC 3501 = DSM 20602	scaffold	GCA_001434535	930942.11	2657245445	930942	66.07

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Lactobacillus animalis 16S ribosomal RNA	M58807	1507	1605
20218	Lactobacillus animalis genes for 16S-23S intergenic spacer region, 23S ribosomal RNA, strain:JCM 5670	AB158765	2932	930942
20218	Lactobacillus animalis gene for 16S rRNA, partial sequence, strain: JCM 5670	AB289042	688	930942
20218	Lactobacillus animalis gene for 16S rRNA, partial sequence, strain: NBRC 15882	AB326350	1489	930942
20218	L.animalis 16S rRNA gene	X61133	1406	930942
67770	Lactobacillus animalis gene for 16S ribosomal RNA, partial sequence, strain: JCM 5670	LC071814	1458	930942

GC content

@ref	GC-content (mol%)	Method
8950	42.4
67770	41.1	genome sequence analysis

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Ligilactobacillus animalis KCTC 3501 = DSM 20602
NCBI: GCA_000183825

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	57.10	no
125439	motility	BacteriaNetⓘ	no	66.60	no
125439	gram_stain	BacteriaNetⓘ	variable	76.50	no
125439	oxygen_tolerance	BacteriaNetⓘ	microaerophile	99.10	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Lactobacillus animalis KCTC 3501
PATRIC: 930942.3

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	92.52	no
125438	anaerobic	anaerobicⓘ	no	87.81	no
125438	aerobic	aerobicⓘ	no	97.01	yes
125438	spore-forming	spore-formingⓘ	no	86.37	no
125438	thermophilic	thermophileⓘ	no	95.46	yes
125438	flagellated	motile2+ⓘ	no	89.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Engineered mycosporine-based glucoconjugates by enzymatic cascade: Towards innovative ultraviolet filters and antioxidant compounds.	Bascans E, Severac E, Guieysse D, Claverie M, Blanc S, Remaud-Simeon M, Fernandes SCM, Moulis C.	Bioresour Technol	10.1016/j.biortech.2025.132721	2025
	Efficacy of a feed additive consisting of Enterococcus faeciumDSM 33761, Pediococcus acidilacticiDSM 33758, Bifidobacterium animalisDSM 16284, Limosilactobacillus reuteriDSM 33751, Ligilactobacillus salivariusDSM 16351 (Biomin® C5) as a zootechnical additive for poultry for fattening and reared for laying/breeding (Biomin GmbH).	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, Lopez-Alonso M, Marcon F, Nebbia C, Pechova A, Prieto-Maradona M, Rohe I, Theodoridou K, Dierick N, Anguita M, Innocenti ML, Ortuno J.	EFSA J	10.2903/j.efsa.2025.9459	2025
	Conversion of oleuropein to hydroxytyrosol by lactic acid bacteria fermentation of olive leaves in water solution with reduced glucose content.	Farkas Z, Romeo R, Pangallo D, Krakova L, Giuffre AM, Sidari R.	World J Microbiol Biotechnol	10.1007/s11274-025-04495-4	2025
Pathogenicity	Different effects of soybean protein and its derived peptides on the growth and metabolism of Bifidobacterium animalis subsp. animalis JCM 1190.	Li W, Li H, Zhang Y, He L, Zhang C, Liu X.	Food Funct	10.1039/d1fo00480h	2021
	Lactobacillus Johnsonii YH1136 alleviates schizophrenia-like behavior in mice: a gut-microbiota-brain axis hypothesis study.	Zheng L, Xin J, Ye H, Sun N, Gan B, Gong X, Bao S, Xiang M, Wang H, Ni X, Li H, Zhang T.	BMC Microbiol	10.1186/s12866-025-03893-w	2025
Phylogeny	Characterization of an Enterococcus sp. SMC-9 strain isolated from bile of a patient with cholangitis.	Yu S, Kang M, Yoo Y, Kim TY, Huh HJ, Lee NY.	PLoS One	10.1371/journal.pone.0312953	2024
	Lactobacilli and Bifidobacteria: A Parapostbiotic Approach to Study and Explain Their Mutual Bioactive Influence.	Altieri C, Filippone A, Bevilacqua A, Corbo MR, Sinigaglia M.	Foods	10.3390/foods13182966	2024
Metabolism	In ovo probiotic supplementation enhances energy status and promotes growth in developing broiler embryos and hatchlings.	Gao M, Ren Y, Amalaradjou MA.	Poult Sci	10.1016/j.psj.2025.105442	2025
	Assessment of a feed additive consisting of Lentilactobacillus buchneriDSM 19455 for all animal species for the renewal of its authorisation (Biomin GmbH).	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Bampidis V, Azimonti G, Bastos ML, Christensen H, Durjava M, Dusemund B, Kouba M, Lopez-Alonso M, Lopez Puente S, Marcon F, Mayo B, Pechova A, Petkova M, Ramos F, Villa RE, Woutersen R, Alija-Novo N, Anguita M, Galobart J, Garcia-Cazorla Y, Innocenti M, Vettori MV, Brozzi R.	EFSA J	10.2903/j.efsa.2023.8352	2023
	Probiotic supplementation as an alternative to antibiotics in broiler chickens.	Tomczyk G, Niczyporuk JS, Kozdrun W, Sawicka-Durkalec A, Bocian L, Barabasz M, Michalski M.	J Vet Res	10.2478/jvetres-2024-0009	2024
	Apple Waste/By-Products and Microbial Resources to Promote the Design of Added-Value Foods: A Review.	Selmi H, Presutto E, Totaro M, Spano G, Capozzi V, Fragasso M.	Foods	10.3390/foods14111850	2025
	Antimicrobial activity of cell-free supernatant of lactic acid bacteria on spoilage bacteria of vacuum-packed sliced emulsion-type sausages.	Tajbakhsh S, Eskandari MH, Shekarforoush SS.	Iran J Vet Res	10.22099/ijvr.2024.49361.7255	2024
Pathogenicity	Inhibitory effects of seaweed extracts on the growth of the vaginal bacterium Gardnerella vaginalis.	Ha YM, Choi JS, Lee BB, Moon HE, Cho KK, Choi IS.	J Environ Biol		2014
	The human intestinal bacterium Eggerthella lenta influences gut metabolomes in gnotobiotic mice	Viehof A, Haange S, Streidl T, Schubert K, Engelmann B, Haller D, Rolle-Kampczyk U, von Bergen M, Clavel T.	Microbiome Res Rep		2024
	Diversity of a Lactic Acid Bacterial Community during Fermentation of Gajami-Sikhae, a Traditional Korean Fermented Fish, as Determined by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry.	Kim E, Won JE, Yang SM, Kim HJ, Kim HY.	Foods	10.3390/foods11070909	2022
	Probiotics as technological innovations in psychiatric disorders: patents and research reviews.	de Lima AA, Santos SS, de Araujo MA, Vinderola G, Villarreal CF, Viana MDM.	Front Nutr	10.3389/fnut.2025.1567097	2025
	Flagellar Genes Are Associated with the Colonization Persistence Phenotype of the Drosophila melanogaster Microbiota.	Morgan SJ, Chaston JM.	Microbiol Spectr	10.1128/spectrum.04585-22	2023
Biotechnology	Development of Delivery Systems with Prebiotic and Neuroprotective Potential of Industrial-Grade Cannabis sativa L.	Sip S, Stasilowicz-Krzemien A, Sip A, Szulc P, Neumann M, Kryszak A, Cielecka-Piontek J.	Molecules	10.3390/molecules29153574	2024
	Molecular and biotechnological characteristics of proteolytic activity from Streptococcus thermophilus as a proteolytic lactic acid bacteria to enhance protein-derived bioactive peptides.	Phupaboon S, Hashim FJ, Phumkhachorn P, Rattanachaikunsopon P.	AIMS Microbiol	10.3934/microbiol.2023031	2023
	Assessment of the feed additive consisting of Enterococcus faecium DSM 21913, Bifidobacterium animalis DSM 16284 and Ligilactobacillus salivarius DSM 16351 (Biomin® C3) for chickens for fattening, chickens reared for laying and minor poultry species other than laying for the renewal of its authorisation and extension of use in all poultry species for fattening and reared for laying/breeding (Biomin GmbH).	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Bampidis V, Azimonti G, Bastos ML, Christensen H, Dusemund B, Durjava M, Kouba M, Lopez-Alonso M, Lopez Puente S, Marcon F, Mayo B, Pechova A, Petkova M, Ramos F, Villa RE, Woutersen R, Ortuno Casanova J, Pettenati E.	EFSA J	10.2903/j.efsa.2023.8356	2023
Enzymology	Isolation and characterization of bacteriocin-producing bacteria from the intestinal microbiota of elderly Irish subjects.	Lakshminarayanan B, Guinane CM, O'Connor PM, Coakley M, Hill C, Stanton C, O'Toole PW, Ross RP.	J Appl Microbiol	10.1111/jam.12085	2013
	The role of Bifidobacterium in longevity and the future of probiotics.	Ku S, Haque MA, Jang MJ, Ahn J, Choe D, Jeon JI, Park MS.	Food Sci Biotechnol	10.1007/s10068-024-01631-y	2024
	The effect of probiotics on functional constipation in adults: Double-blind, randomized, placebo-controlled study.	Mitelmao FCR, Bergamaschi CC, Gerenutti M, Hachel K, Silva MT, Balcao VM, Vila MMDC.	Medicine (Baltimore)	10.1097/md.0000000000024938	2021
	Alginate- and Gelatin-Coated Apple Pieces as Carriers for Bifidobacterium animalis subsp. lactis DSM 10140.	Campaniello D, Bevilacqua A, Speranza B, Sinigaglia M, Corbo MR.	Front Microbiol	10.3389/fmicb.2020.566596	2020
	Preservation characteristics and bacterial communities of crimped ensiled barley grains modulated by moisture content and additive application.	Franco M, Tapio I, Rinne M.	Front Microbiol	10.3389/fmicb.2022.1092062	2022
	Alginate Alleviates Dextran Sulfate Sodium-Induced Colitis by Promoting Bifidobacterium animalis and Intestinal Hyodeoxycholic Acid Synthesis in Mice.	Pi Y, Zhang X, Wu Y, Wang Z, Bai Y, Liu X, Han D, Zhao J, Tobin I, Zhao J, Zhang G, Wang J.	Microbiol Spectr	10.1128/spectrum.02979-22	2022
	Safety and efficacy of a feed additive consisting of Enterococcus faecium DSM 33761, Pediococcus acidilactici DSM 33758, Bifidobacterium animalis DSM 16284, Limosilactobacillus reuteri DSM 33751 and Ligilactobacillus salivarius DSM 16351 (Biomin® C5) for chickens for fattening, chickens reared for laying, turkeys for fattening, turkeys reared for breeding and minor poultry species for fattening and reared for laying/breeding (Biomin GmbH).	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Bampidis V, Azimonti G, Bastos ML, Christensen H, Dusemund B, Durjava M, Kouba M, Lopez-Alonso M, Lopez Puente S, Marcon F, Mayo B, Pechova A, Petkova M, Ramos F, Villa RE, Woutersen R, Ortuno Casanova J, Pettenati E.	EFSA J	10.2903/j.efsa.2023.8354	2023
	In vitro antioxidative properties of lactobacilli.	Kim HS, Chae HS, Jeong SG, Ham JS, Im SK, Ahn CN, Lee JM.	Asian-Australas J Anim Sci		2006
	Recombinant Bifidobacterium longum Carrying Endostatin Protein Alleviates Dextran Sodium Sulfate-Induced Colitis and Colon Cancer in Rats.	Bi Z, Cui E, Yao Y, Chang X, Wang X, Zhang Y, Xu GX, Zhuang H, Hua ZC.	Front Microbiol	10.3389/fmicb.2022.927277	2022
	Selection of Enzymatic Treatments for Upcycling Lentil Hulls into Ingredients Rich in Oligosaccharides and Free Phenolics.	Bautista-Exposito S, Vandenberg A, Duenas M, Penas E, Frias J, Martinez-Villaluenga C.	Molecules	10.3390/molecules27238458	2022
	A randomized double-blind placebo controlled pilot study of probiotics in adolescents with severe obesity.	Verma A, Nelson MT, DePaolo WR, Hampe C, Roth CL.	J Diabetes Metab Disord	10.1007/s40200-021-00855-7	2021
	Fermentation of Cucumber Extract with Hydromagnesite as a Neutralizing Agent to Produce an Ingredient for Dermal Magnesium Products.	Nguyen VK, Tran T, Crimmins T, Luong VT, Kang HY.	Materials (Basel)	10.3390/ma12101701	2019
	Globe Artichoke (Cynara scolymus L.) By-Products in Food Applications: Functional and Biological Properties.	Colombo R, Moretto G, Pellicorio V, Papetti A.	Foods	10.3390/foods13101427	2024
	A dynamic model that simulates the human upper gastrointestinal tract for the study of probiotics.	Mainville I, Arcand Y, Farnworth ER.	Int J Food Microbiol	10.1016/j.ijfoodmicro.2004.08.020	2005
	Stability of recombinant plasmids on the continuous culture of Bifidobacterium animalis ATCC 27536.	Gonzalez Vara A, Rossi M, Altomare L, Eikmanns B, Matteuzzi D.	Biotechnol Bioeng	10.1002/bit.10737	2003
Pathogenicity	Abiraterone acetate preferentially enriches for the gut commensal Akkermansia muciniphila in castrate-resistant prostate cancer patients.	Daisley BA, Chanyi RM, Abdur-Rashid K, Al KF, Gibbons S, Chmiel JA, Wilcox H, Reid G, Anderson A, Dewar M, Nair SM, Chin J, Burton JP.	Nat Commun	10.1038/s41467-020-18649-5	2020
	Persistence and Effect of a Multistrain Starter Culture on Antioxidant and Rheological Properties of Novel Wheat Sourdoughs and Bread.	Sidari R, Martorana A, Zappia C, Mincione A, Giuffre AM.	Foods	10.3390/foods9091258	2020
	Effect of adding Propionibacterium shermanii NCDO 853 or Lactobacillus casei ssp. casei IFPL 731 on proteolysis and flavor development of Cheddar cheese.	Fernandez-Espla MD, Fox PF.	J Agric Food Chem	10.1021/jf970535k	1998
Metabolism	First evidence of production of the lantibiotic nisin P.	Garcia-Gutierrez E, O'Connor PM, Saalbach G, Walsh CJ, Hegarty JW, Guinane CM, Mayer MJ, Narbad A, Cotter PD.	Sci Rep	10.1038/s41598-020-60623-0	2020
Metabolism	The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice.	Streidl T, Karkossa I, Segura Munoz RR, Eberl C, Zaufel A, Plagge J, Schmaltz R, Schubert K, Basic M, Schneider KM, Afify M, Trautwein C, Tolba R, Stecher B, Doden HL, Ridlon JM, Ecker J, Moustafa T, von Bergen M, Ramer-Tait AE, Clavel T.	Gut Microbes	10.1080/19490976.2020.1854008	2021
Metabolism	The gut anaerobe Faecalibacterium prausnitzii uses an extracellular electron shuttle to grow at oxic-anoxic interphases.	Khan MT, Duncan SH, Stams AJ, van Dijl JM, Flint HJ, Harmsen HJ.	ISME J	10.1038/ismej.2012.5	2012
	Incidence of Bacteriocins Produced by Food-Related Lactic Acid Bacteria Active towards Oral Pathogens.	Zoumpopoulou G, Pepelassi E, Papaioannou W, Georgalaki M, Maragkoudakis PA, Tarantilis PA, Polissiou M, Tsakalidou E, Papadimitriou K.	Int J Mol Sci	10.3390/ijms14034640	2013
Metabolism	Use of a novel Escherichia coli-leuconostoc shuttle vector for metabolic engineering of Leuconostoc citreum to overproduce D-lactate.	Chae HS, Lee SH, Lee JH, Park SJ, Lee PC.	Appl Environ Microbiol	10.1128/aem.03291-12	2013
Phylogeny	Investigation of the evolutionary development of the genus Bifidobacterium by comparative genomics.	Lugli GA, Milani C, Turroni F, Duranti S, Ferrario C, Viappiani A, Mancabelli L, Mangifesta M, Taminiau B, Delcenserie V, van Sinderen D, Ventura M.	Appl Environ Microbiol	10.1128/aem.02004-14	2014
Enzymology	Phylogenetic analysis of faecal microbiota from captive cheetahs reveals underrepresentation of Bacteroidetes and Bifidobacteriaceae.	Becker AA, Hesta M, Hollants J, Janssens GP, Huys G.	BMC Microbiol	10.1186/1471-2180-14-43	2014
Genetics	Genus-Wide Assessment of Antibiotic Resistance in Lactobacillus spp.	Campedelli I, Mathur H, Salvetti E, Clarke S, Rea MC, Torriani S, Ross RP, Hill C, O'Toole PW.	Appl Environ Microbiol	10.1128/aem.01738-18	2019
Pathogenicity	Irinotecan (CPT-11) chemotherapy alters intestinal microbiota in tumour bearing rats.	Lin XB, Dieleman LA, Ketabi A, Bibova I, Sawyer MB, Xue H, Field CJ, Baracos VE, Ganzle MG.	PLoS One	10.1371/journal.pone.0039764	2012
Metabolism	Expression of a secretory alpha-glucosidase II from Apis cerana indica in Pichia pastoris and its characterization.	Kaewmuangmoon J, Kilaso M, Leartsakulpanich U, Kimura K, Kimura A, Chanchao C.	BMC Biotechnol	10.1186/1472-6750-13-16	2013
Phylogeny	Influence of geographical origin and flour type on diversity of lactic acid bacteria in traditional Belgian sourdoughs.	Scheirlinck I, Van der Meulen R, Van Schoor A, Vancanneyt M, De Vuyst L, Vandamme P, Huys G, Huys G.	Appl Environ Microbiol	10.1128/aem.00894-07	2007
Pathogenicity	Resistant starches types 2 and 4 have differential effects on the composition of the fecal microbiota in human subjects.	Martinez I, Kim J, Duffy PR, Schlegel VL, Walter J.	PLoS One	10.1371/journal.pone.0015046	2010
Metabolism	Accumulation of trans C18:1 fatty acids in the rumen after dietary algal supplementation is associated with changes in the Butyrivibrio community.	Boeckaert C, Vlaeminck B, Fievez V, Maignien L, Dijkstra J, Boon N.	Appl Environ Microbiol	10.1128/aem.01473-08	2008
	Development of innovative pediocin PA-1 by DNA shuffling among class IIa bacteriocins.	Tominaga T, Hatakeyama Y.	Appl Environ Microbiol	10.1128/aem.00558-07	2007
Phylogeny	Denaturing gradient gel electrophoresis analysis of the 16S rRNA gene V1 region to monitor dynamic changes in the bacterial population during fermentation of Italian sausages.	Cocolin L, Manzano M, Cantoni C, Comi G.	Appl Environ Microbiol	10.1128/aem.67.11.5113-5121.2001	2001
Metabolism	Jenseniin G, a heat-stable bacteriocin produced by Propionibacterium jensenii P126.	Grinstead DA, Barefoot SF.	Appl Environ Microbiol	10.1128/aem.58.1.215-220.1992	1992
Enzymology	Prophage-like elements in bifidobacteria: insights from genomics, transcription, integration, distribution, and phylogenetic analysis.	Ventura M, Lee JH, Canchaya C, Zink R, Leahy S, Moreno-Munoz JA, O'Connell-Motherway M, Higgins D, Fitzgerald GF, O'Sullivan DJ, van Sinderen D.	Appl Environ Microbiol	10.1128/aem.71.12.8692-8705.2005	2005
	A critical evaluation of methodological and mechanistic insights on probiotic-derived extracellular vesicles.	Ronacher C, Gonzalez CF, Lorca GL.	Front Nutr	10.3389/fnut.2025.1632232	2025
Pathogenicity	Novel Horizons in Postbiotics: Lactobacillaceae Extracellular Vesicles and Their Applications in Health and Disease.	Gonzalez-Lozano E, Garcia-Garcia J, Galvez J, Hidalgo-Garcia L, Rodriguez-Nogales A, Rodriguez-Cabezas ME, Sanchez M.	Nutrients	10.3390/nu14245296	2022
	Extracellular Vesicles of Probiotics: Shedding Light on the Biological Activity and Future Applications.	Krzyzek P, Marinacci B, Vitale I, Grande R.	Pharmaceutics	10.3390/pharmaceutics15020522	2023
Genetics	Genome sequence of Lactobacillus animalis KCTC 3501.	Nam SH, Choi SH, Kang A, Kim DW, Kim RN, Kim A, Kim DS, Park HS	J Bacteriol	10.1128/JB.01505-10	2010
Phylogeny	Virgibacillus phasianinus sp. nov., a halophilic bacterium isolated from faeces of a Swinhoe's pheasant, Lophura swinhoii.	Tak EJ, Kim HS, Lee JY, Kang W, Sung H, Kim PS, Hyun DW, Shin NR, Roh JR, Park SD, Shim HE, Bae JW.	Int J Syst Evol Microbiol	10.1099/ijsem.0.002650	2018
Phylogeny	Bifidobacterium faecale sp. nov., isolated from human faeces.	Choi JH, Lee KM, Lee MK, Cha CJ, Kim GB.	Int J Syst Evol Microbiol	10.1099/ijs.0.063479-0	2014
Phylogeny	Lactobacillus heilongjiangensis sp. nov., isolated from Chinese pickle.	Gu CT, Li CY, Yang LJ, Huo GC.	Int J Syst Evol Microbiol	10.1099/ijs.0.053355-0	2013
Phylogeny	Lactobacillus yonginensis sp. nov., a lactic acid bacterium with ginsenoside converting activity isolated from Kimchi.	Yi EJ, Yang JE, Lee JM, Park Y, Park SY, Shin HS, Kook M, Yi TH.	Int J Syst Evol Microbiol	10.1099/ijs.0.045799-0	2013
Phylogeny	Lactobacillus paucivorans sp. nov., isolated from a brewery environment.	Ehrmann MA, Preissler P, Danne M, Vogel RF.	Int J Syst Evol Microbiol	10.1099/ijs.0.018077-0	2010
Phylogeny	Reclassification of Lactobacillus amylophilus LMG 11400 and NRRL B-4435 as Lactobacillus amylotrophicus sp. nov.	Naser SM, Vancanneyt M, Snauwaert C, Vrancken G, Hoste B, De Vuyst L, Swings J.	Int J Syst Evol Microbiol	10.1099/ijs.0.64463-0	2006
Phylogeny	Lactobacillus apodemi sp. nov., a tannase-producing species isolated from wild mouse faeces.	Osawa R, Fujisawa T, Pukall R	Int J Syst Evol Microbiol	10.1099/ijs.0.64147-0	2006

References

#8950	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 20602
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#40543	; Curators of the CIP;
#51813	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 33906
#66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68371	Automatically annotated from API 50CH acid .
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#116392	Collection of Institut Pasteur ; Curators of the CIP; CIP 103152
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Ligilactobacillus animalis (DSM 20602, ATCC 35046, NCDO 2425)

Name and taxonomic classification

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Physiology and metabolism

Oxygen tolerance

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Metabolite tests

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API zym

API 50CHac

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Genome browser: GCA_000183825

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