Corynebacterium diphtheriae 48255 is a bacterium that was isolated from throat culture.
genome sequence 16S sequence Bacteria| @ref 20215 |
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Last LPSN update
2026-05-29 08:25:38 |
| Domain Bacteria |
| Phylum Actinomycetota |
| Class Actinomycetes |
| Order Mycobacteriales |
| Family Corynebacteriaceae |
| Genus Corynebacterium |
| Species Corynebacterium diphtheriae |
| Full scientific name Corynebacterium diphtheriae (Kruse 1886) Lehmann and Neumann 1896 (Approved Lists 1980) |
| Synonyms (1) |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 11438 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | Medium recipe at MediaDive  | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base | ||
| 11438 | TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) | Medium recipe at MediaDive | Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water |
| @ref | Oxygen tolerance | Confidence | |
|---|---|---|---|
| 125439 | facultative anaerobe | 92.27 |
| @ref | Spore formation | Confidence | |
|---|---|---|---|
| 125439 | 98.778 |
| 67770 | Observationquinones: MK-8(H2) |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68379 | 17634 ChEBI | D-glucose | + | fermentation | from API Coryne |
| 68379 | 16899 ChEBI | D-mannitol | - | fermentation | from API Coryne |
| 68379 | 16988 ChEBI | D-ribose | + | fermentation | from API Coryne |
| 68379 | 65327 ChEBI | D-xylose | - | fermentation | from API Coryne |
| 68379 | 4853 ChEBI | esculin | - | hydrolysis | from API Coryne |
| 68379 | 5291 ChEBI | gelatin | - | hydrolysis | from API Coryne |
| 68379 | 28087 ChEBI | glycogen | - | fermentation | from API Coryne |
| 68379 | 17716 ChEBI | lactose | - | fermentation | from API Coryne |
| 68379 | 17306 ChEBI | maltose | + | fermentation | from API Coryne |
| 68379 | 17632 ChEBI | nitrate | + | reduction | from API Coryne |
| 68379 | 17992 ChEBI | sucrose | - | fermentation | from API Coryne |
| 68379 | 16199 ChEBI | urea | - | hydrolysis | from API Coryne |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68379 | alkaline phosphatase | - | 3.1.3.1 | from API Coryne |
| 68379 | beta-galactosidase | - | 3.2.1.23 | from API Coryne |
| 68379 | beta-glucosidase | - | 3.2.1.21 | from API Coryne |
| 68379 | beta-glucuronidase | - | 3.2.1.31 | from API Coryne |
| 68379 | catalase | + | 1.11.1.6 | from API Coryne |
| 68379 | gelatinase | - | from API Coryne | |
| 68379 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API Coryne |
| 68379 | pyrazinamidase | - | 3.5.1.B15 | from API Coryne |
| 68379 | pyrrolidonyl arylamidase | - | 3.4.19.3 | from API Coryne |
| 68379 | urease | - | 3.5.1.5 | from API Coryne |
| Cat1 | Cat2 | Cat3 | |
|---|---|---|---|
| #Engineered | #Laboratory | #Lab enrichment | |
| #Host Body-Site | #Oral cavity and airways | #Throat |
Global distribution of 16S sequence LC102487 (>99% sequence identity) for Corynebacterium diphtheriae from Microbeatlas 
 Aquatic Samples |
4794 |
 Soil Samples |
3296 |
 Animal Samples |
29947 |
 Plant Samples |
1078 |
| Total Samples | 39115 |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 66792 | Corynebacterium diphtheriae strain FDAARGOS_1552 | complete | 1717.766  | 1717 | 99.51 | | ||
| 124043 | ASM2073612v1 assembly for Corynebacterium diphtheriae FDAARGOS_1552 | complete | GCA_020736125  | 1717.762 | 1717 | 98.81 | | |
| 67770 | ASM45578v1 assembly for Corynebacterium diphtheriae DSM 43988 | contig | GCA_000455785 | 1206106.3 | 2541047477  | 1206106 | 11.98 |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 67770 | Corynebacterium diphtheriae gene for 16S ribosomal RNA, partial sequence, strain: JCM 1310 | LC102487 | 1380 | | 1717 |
| @ref | GC-content (mol%) | Method | |
|---|---|---|---|
| 67770 | 52.4 | thermal denaturation, midpoint method (Tm) |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Corynebacterium diphtheriae Virulence Analyses Using a Caenorhabditis elegans Model. | Chen YW, Ton-That H. | Curr Protoc Microbiol | 10.1002/cpmc.109 | 2020 | | |
| Analysis of Corynebacterium diphtheriae macrophage interaction: Dispensability of corynomycolic acids for inhibition of phagolysosome maturation and identification of a new gene involved in synthesis of the corynomycolic acid layer. | Ott L, Hacker E, Kunert T, Karrington I, Etschel P, Lang R, Wiesmann V, Wittenberg T, Singh A, Varela C, Bhatt A, Sangal V, Burkovski A. | PLoS One | 10.1371/journal.pone.0180105 | 2017 | | |
| Enzymology | Dual color fluorescence in situ hybridization (FISH) assays for detecting Mycobacterium tuberculosis and Mycobacterium avium complexes and related pathogens in cultures. | Shah J, Weltman H, Narciso P, Murphy C, Poruri A, Baliga S, Sharon L, York M, Cunningham G, Miller S, Caviedes L, Gilman R, Desmond E, Ramasamy R. | PLoS One | 10.1371/journal.pone.0174989 | 2017 | |
| Metabolism | Toll-Like Receptor 2 and Mincle Cooperatively Sense Corynebacterial Cell Wall Glycolipids. | Schick J, Etschel P, Bailo R, Ott L, Bhatt A, Lepenies B, Kirschning C, Burkovski A, Lang R. | Infect Immun | 10.1128/iai.00075-17 | 2017 | |
| Metabolism | An inhibitory compound produced by a soil isolate of Rhodococcus has strong activity against the veterinary pathogen R. equi. | Ward AL, Reddyvari P, Borisova R, Shilabin AG, Lampson BC. | PLoS One | 10.1371/journal.pone.0209275 | 2018 | |
| Metabolism | Reconstitution experiments and gene deletions reveal the existence of two-component major cell wall channels in the genus Corynebacterium. | Barth E, Barcelo MA, Klackta C, Benz R. | J Bacteriol | 10.1128/jb.01142-09 | 2010 | |
| Metabolism | Rapid determination of Corynebacterium diphtheriae toxigenicity by counterimmunoelectrophoresis. | Thompson NL, Ellner PD. | J Clin Microbiol | 10.1128/jcm.7.5.493-494.1978 | 1978 | |
| Enzymology | Multiplex real-time PCR assay for rapid detection of methicillin-resistant staphylococci directly from positive blood cultures. | Wang HY, Kim S, Kim J, Park SD, Uh Y, Lee H. | J Clin Microbiol | 10.1128/jcm.00389-14 | 2014 | |
| Enzymology | Detection of Mycobacterium tuberculosis by PCR amplification with pan-Mycobacterium primers and hybridization to an M. tuberculosis-specific probe. | Tevere VJ, Hewitt PL, Dare A, Hocknell P, Keen A, Spadoro JP, Young KK. | J Clin Microbiol | 10.1128/jcm.34.4.918-923.1996 | 1996 | |
| Phylogeny | Detection and genotyping of Mycobacterium species from clinical isolates and specimens by oligonucleotide array. | Park H, Jang H, Song E, Chang CL, Lee M, Jeong S, Park J, Kang B, Kim C. | J Clin Microbiol | 10.1128/jcm.43.4.1782-1788.2005 | 2005 | |
| Multiplex strand displacement amplification (SDA) and detection of DNA sequences from Mycobacterium tuberculosis and other mycobacteria. | Walker GT, Nadeau JG, Spears PA, Schram JL, Nycz CM, Shank DD. | Nucleic Acids Res | 10.1093/nar/22.13.2670 | 1994 | | |
| Metabolism | SIALIDASE (NEURAMINIDASE) OF CORYNEBACTERIUM DIPHTHERIAE. | WARREN L, SPEARING CW. | J Bacteriol | 10.1128/jb.86.5.950-955.1963 | 1963 | |
| Enzymology | Novel, rapid optical immunoassay technique for detection of group A streptococci from pharyngeal specimens: comparison with standard culture methods. | Harbeck RJ, Teague J, Crossen GR, Maul DM, Childers PL. | J Clin Microbiol | 10.1128/jcm.31.4.839-844.1993 | 1993 | |
| Enzymology | The superoxide dismutase gene, a target for detection and identification of mycobacteria by PCR. | Zolg JW, Philippi-Schulz S. | J Clin Microbiol | 10.1128/jcm.32.11.2801-2812.1994 | 1994 | |
| Enzymology | Diphtheria bacilli isolated in Alberta in 1967 from the throat, nose, ears and skin. | Dixon JM, Thorsteinson S. | Can Med Assoc J | 1969 | | |
| Phylogeny | Numerical taxonomy of certain coryneform bacteria. | da Silva GA, Holt JG. | J Bacteriol | 10.1128/jb.90.4.921-927.1965 | 1965 | |
| Shared antigens between heterologous bacterial species. | Minden P, McClatchy JK, Farr RS. | Infect Immun | 10.1128/iai.6.4.574-582.1972 | 1972 | | |
| Metabolism | Superoxide dismutase and oxygen metabolism in Streptococcus faecalis and comparisons with other organisms. | Britton L, Malinowski DP, Fridovich I. | J Bacteriol | 10.1128/jb.134.1.229-236.1978 | 1978 | |
| Antioxidant and antibacterial effects of medicinal plants and their stick-type medicinal concentrated beverages. | Chang HJ, Kim YH, Kang YH, Choi MH, Lee JH. | Food Sci Biotechnol | 10.1007/s10068-020-00793-9 | 2020 | | |
| High-Throughput Sequencing Analysis of the Actinobacterial Spatial Diversity in Moonmilk Deposits. | Maciejewska M, Calusinska M, Cornet L, Adam D, Pessi IS, Malchair S, Delfosse P, Baurain D, Barton HA, Carnol M, Rigali S. | Antibiotics (Basel) | 10.3390/antibiotics7020027 | 2018 | | |
| Enzymology | Identification and functional characterization of the NanH extracellular sialidase from Corynebacterium diphtheriae. | Kim S, Oh DB, Kwon O, Kang HA | J Biochem | 10.1093/jb/mvp198 | 2009 | |
| Metabolism | Corynebacterium diphtheriae: identification and characterization of a channel-forming protein in the cell wall. | Schiffler B, Barth E, Daffe M, Benz R | J Bacteriol | 10.1128/JB.00864-07 | 2007 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive3151.20260601.11
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
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