Burkholderia cepacia (DSM 7288, ATCC 25416, DSM 9897)

Name: Burkholderia cepacia (DSM 7288, ATCC 25416, DSM 9897)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 1906

Type strain

Strain Designation 717

Culture col. no. DSM 7288 ATCC 25416 DSM 9897 ICPB PC25 NCTC 10743 16 more

NCBI tax ID(s) 983594 292

Special Collections DSMZ CCUG JCM KCTC CIP

History <- ATCC; ATCC 25416 <- R. W. Ballard; 717 <- M. P. Starr, ICPB; ICPB PC25 <- W. H. Burkholder; Y. Kosako 85005 <-- Nissui Pharm. Co., Ltd. <-- ATCC 25416 <-- R. W. Ballard 717 <-- M. Starr ICPB PC 25 <-- W. Burkholder. CIP <- 1980, C. Richard, Inst. Pasteur, Paris, France <- ATCC <- R.W. Ballard: strain 717 <- M.P. Starr <- W.H. Burkholder, Pseudomonas cepacia

Links

Burkholderia cepacia 717 is an obligate aerobe, Gram-negative, motile human pathogen that has multiple antibiotic resistances and was isolated from Onion.

antibiotic resistance Gram-negative motile rod-shaped obligate aerobe human pathogen genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 3962

LMG 1222,ATCC 25416,CCUG 12691,CCUG 13226,DSM 7288,ICMP 5796,IFO 14074,JCM 5964,NCTC 10743,PDDCC 5796,NBIMCC 8566,ACM 1771,CCRC 13208,NCIMB 13694,CIP 80.24,CECT 4137,CCRC 10735,CFBP 2227,VTT E-94512,KCTC 2966,AS 1.1813,NBRC 14074,NRRL B-14810,NCCB 76047,LMD 76.47,HAMBI 1976,BCRC 10735,BCRC 13208,CCT 0593,KACC 10167,NCAIM B.02058,CGMCC 1.1813,CCMM B557

@ref 20215

Last LPSN update 2026-02-09 11:18:12

Domain Bacteria

Phylum Pseudomonadota

Class Betaproteobacteria

Order Burkholderiales

Family Burkholderiaceae

Genus Burkholderia

Species Burkholderia cepacia

Full scientific name Burkholderia cepacia (Palleroni and Holmes 1981 ex Burkholder 1950) Yabuuchi et al. 1993

Synonyms (2)

Pseudomonas cepacia
"Pseudomonas cepacia"

BacDive ID	Other strains from **Burkholderia cepacia** (89)	Type strain
1907	B. cepacia DSM 9241, IPT 16
1908	B. cepacia PB4, DSM 12775
1909	B. cepacia B-175, DSM 50180, ATCC 17770, NCIB 9089, ...
1910	B. cepacia 8, DSM 50181, ATCC 17759, ICPB 2745-382, ...
100173	B. cepacia STI09278(IMET), LA6, IFO 14915, IMET 9278, ...
134989	B. cepacia 69.87, CIP 102834
135284	B. cepacia CIP 79.24
135991	B. cepacia CIP 82.38
136118	B. cepacia 652.86, CIP 102649
136877	B. cepacia 105-79, CIP 82.35
137198	B. cepacia 134-79, CIP 82.37
137604	B. cepacia 189-79, CIP 80.3
137808	B. cepacia 176-79, CIP 82.36
137861	B. cepacia 913-85, CIP 101953
138044	B. cepacia CIP 102577
138697	B. cepacia 74-86, CIP 102142
138925	B. cepacia CIP 66.34
139162	B. cepacia CIP 82.39
139163	B. cepacia CIP 82.40
139298	B. cepacia B37w, CIP 105028, ATCC 51671, NRRL B-14858
141301	B. cepacia CCUG 787, LMG 6032
141322	B. cepacia CCUG 853, LMG 6987 1
141323	B. cepacia CCUG 854
141400	B. cepacia CCUG 1440, LMG 6995
141402	B. cepacia CCUG 1463 B
141498	B. cepacia CCUG 2393
141559	B. cepacia CCUG 3000
141565	B. cepacia CCUG 3091
141578	B. cepacia CCUG 3305
141604	B. cepacia CCUG 3461 B, LMG 6997
141623	B. cepacia CCUG 3952
141709	B. cepacia CCUG 5053
141726	B. cepacia CCUG 5443
142084	B. cepacia CCUG 10531
142145	B. cepacia CCUG 11026
142155	B. cepacia CCUG 11212
143661	B. cepacia CCUG 20858
143938	B. cepacia CCUG 22001
144069	B. cepacia CCUG 22747
144070	B. cepacia CCUG 22749
144474	B. cepacia CCUG 25105
145457	B. cepacia CCUG 28594
145601	B. cepacia CCUG 28959
145812	B. cepacia CCUG 29661
146115	B. cepacia CCUG 30399
146182	B. cepacia CCUG 30533
146330	B. cepacia CCUG 30929
146447	B. cepacia CCUG 31162
146810	B. cepacia CCUG 32158
147027	B. cepacia CCUG 32669
147028	B. cepacia CCUG 32670
147767	B. cepacia CCUG 34194
147811	B. cepacia CCUG 34268
148075	B. cepacia CCUG 34776
148533	B. cepacia CCUG 35606
148616	B. cepacia CCUG 35721
149225	B. cepacia CCUG 37296
149292	B. cepacia CCUG 37431
149379	B. cepacia CCUG 37614
149396	B. cepacia CCUG 37644
149397	B. cepacia CCUG 37645
149727	B. cepacia CCUG 38286
150244	B. cepacia CCUG 39373
150778	B. cepacia CCUG 42299
150999	B. cepacia CCUG 42980
151312	B. cepacia CCUG 43724
151989	B. cepacia CCUG 45439
153621	B. cepacia CCUG 50324
154226	B. cepacia CCUG 52807
154270	B. cepacia CCUG 52942
154350	B. cepacia CCUG 53202
154485	B. cepacia CCUG 53799
154546	B. cepacia CCUG 54368
154703	B. cepacia CCUG 54885, NCIMB 12757, ATCC 29352, NRRL ...
154943	B. cepacia CCUG 55797
155726	B. cepacia CCUG 59150
155738	B. cepacia CCUG 59169
155755	B. cepacia CCUG 59215
155879	B. cepacia CCUG 59517
155885	B. cepacia CCUG 59535
157311	B. cepacia IMI 347462
163422	B. cepacia JCM 2800, GIFU 627
163423	B. cepacia JCM 2801, GIFU 644
165271	B. cepacia JCM 5506
165272	B. cepacia JCM 5507
165273	B. cepacia JCM 5508
165274	B. cepacia JCM 5509
165275	B. cepacia JCM 5510
165276	B. cepacia JCM 5511

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Motility	Confidence
117247	negative	rod-shaped
125438	negative			97.951

Colony morphology

@ref	Type of hemolysis	Incubation period
3094	gamma	2-3 days

Pigmentation

@ref	Production	Name
117247		Pyocyanin

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
3094	COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)	Medium recipe at MediaDive	Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
3094	R2A MEDIUM (DSMZ Medium 830)	Medium recipe at MediaDive	Name: R2A MEDIUM (DSMZ Medium 830) Composition: Agar 15.0 g/l Casamino acids 0.5 g/l Starch 0.5 g/l Glucose 0.5 g/l Proteose peptone 0.5 g/l Yeast extract 0.5 g/l K2HPO4 0.3 g/l Na-pyruvate 0.3 g/l MgSO4 x 7 H2O 0.05 g/l Distilled water
37582	MEDIUM 72- for trypto casein soja agar		Distilled water make up to (1000.000 ml);Trypto casein soy agar (40.000 g)
117247	CIP Medium 72	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
3094	positive	growth	28
37582	positive	growth	30
67770	positive	growth	30
117247	positive	growth	5-37
117247	negative	growth	41

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
117247	obligate aerobe
125438	aerobe	91.306
125439	aerobe	98.1

Antibiotic susceptibility testing

	Test 1	Test 2	Test 3	Test 4
@ref	3094	3094	3094	3094
Medium	Mueller-Hinton Agar	Mueller-Hinton Agar	Mueller Hinton	M 830
Manual annotation	1	1	1	1
	Inhibition zone diameter in mm	Inhibition zone diameter in mm	Inhibition zone diameter in mm	Inhibition zone diameter in mm
Amikacin 30µg (disc)	10	10	10	0
Ampicillin 10µg (disc)	0	0	0	0
Aztreonam 30µg (disc)	20	20	20	0
Bacitracin 10Unit	0	0	0	n.d.
Cefalotin 30µg (disc)	0	0	0	n.d.
Cefazolin 30µg (disc)	0	0	0	n.d.
Cefiderocol 30µg (disc)	n.d.	n.d.	n.d.	22
Cefotaxime 30µg (disc)	22	22	20	0
Ceftazidime 10µg (disc)	n.d.	n.d.	n.d.	0
Ceftriaxone 30µg (disc)	22	22	22	0
Chloramphenicol 30µg (disc)	20-22	20-22	20-22	16
Ciprofloxacin 5µg (disc)	n.d.	n.d.	n.d.	16-18
Clindamycin 10µg (disc)	0	0	0	0
Colistin 10µg (disc)	0	0	0	n.d.
Colistin sulphate 10µg (disc)	n.d.	n.d.	n.d.	0
Doxycycline 30µg (disc)	20	20	20	n.d.
Erythromycin 15µg (disc)	0	0	6	0
Fosfomycin 50µg (disc)	0	0	0	0
Gentamicin 30µg (disc)	n.d.	n.d.	n.d.	0
Gentamycin 10µg (disc)				n.d.
Imipenem 10µg (disc)	18	18	14	18
Kanamycin 30µg (disc)	12	12	14-16	8-10
Levofloxacin 5µg (disc)	n.d.	n.d.	n.d.	14
Lincomycin 15µg (disc)	0	0	0	n.d.
Linezolid 10µg (disc)	0	0	0	0
Meropenem 10µg (disc)	n.d.	n.d.	n.d.	22
Mezlocillin 30µg (disc)	22-24	22-24	22	n.d.
Moxifloxacin 5µg (disc)	26	26	22-24	12-14
Neomycin 30µg (disc)	10	10	10	n.d.
Nitrofurantoin 100µg (disc)	0	0	0	0
Norfloxacin 10µg (disc)	20	20	16-18	n.d.
Nystatin 100Unit	0	0	0	n.d.
Ofloxacin 5µg (disc)	20	20	18-20	10-12
Oxacillin 5µg (disc)	0	0	0	0
Penicillin G 6µg (disc)	0	0	0	0
Pipemidic acid 20µg (disc)	12	12	10-12	n.d.
Piperacillin/Tazobactam 40µg (disc)	28	28	28-30	n.d.
Piperacillin/Tazobactam 110µg (disc)	n.d.	n.d.	n.d.	0
Polymyxin B 300Unit	0	0	0	0
Quinupristin/Dalfopristin 15µg (disc)	10	10	8-10	0
Rifampicin 5µg (disc)	n.d.	n.d.	n.d.	14
Teicoplanin 30µg (disc)	0	0	0	0
Tetracycline 30µg (disc)	10	10	6	0
Ticarcillin 75µg (disc)	0	0	0	0
Tigecycline 15µg (disc)	n.d.	n.d.	n.d.	0
Trimethoprim-sulfamethoxazole (1:19) 10µg (disc)	n.d.	n.d.	n.d.	18
Vancomycin 30µg (disc)	0	0	0	0

Spore formation

@ref	Spore formation	Confidence
125439		90.3

Compound production

3094

Compoundcepabactin

Halophily

@ref	Salt	Growth	Tested relation	Concentration
117247	NaCl	positive	growth	0-4 %
117247	NaCl		growth	6 %
117247	NaCl		growth	8 %
117247	NaCl		growth	10 %

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68369	17128 ChEBI	adipate	+	assimilation	from API 20NE
68369	29016 ChEBI	arginine	-	hydrolysis	from API 20NE
117247	16947 ChEBI	citrate	+	carbon source
68369	17634 ChEBI	D-glucose	+	assimilation	from API 20NE
68369	16899 ChEBI	D-mannitol	+	assimilation	from API 20NE
68369	16024 ChEBI	D-mannose	+	assimilation	from API 20NE
68369	27689 ChEBI	decanoate	+	assimilation	from API 20NE
117247	4853 ChEBI	esculin	+	hydrolysis
68369	24265 ChEBI	gluconate	+	assimilation	from API 20NE
68369	30849 ChEBI	L-arabinose	+	assimilation	from API 20NE
68369	25115 ChEBI	malate	+	assimilation	from API 20NE
68369	59640 ChEBI	N-acetylglucosamine	+	assimilation	from API 20NE
117247	17632 ChEBI	nitrate	-	reduction
117247	17632 ChEBI	nitrate	-	respiration
68369	17632 ChEBI	nitrate	-	reduction	from API 20NE
117247	16301 ChEBI	nitrite	-	reduction
117247	15882 ChEBI	phenol	+	degradation
68369	27897 ChEBI	tryptophan	-	energy source	from API 20NE
68369	16199 ChEBI	urea	-	hydrolysis	from API 20NE

Antibiotic resistance

@ref	ChEBI	Metabolite	Resistance conc.
117247		0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)
3094	28971	Ampicillin	10 µg (disc)	from Antibiotic test
3094	28669	Bacitracin	10 Unit	from Antibiotic test
3094	124991	Cefalotin	30 µg (disc)	from Antibiotic test
3094	474053	Cefazolin	30 µg (disc)	from Antibiotic test
3094	3508	Ceftazidime	10 µg (disc)	from Antibiotic test
3094	3745	Clindamycin	10 µg (disc)	from Antibiotic test
3094	37943	Colistin	10 µg (disc)	from Antibiotic test
3094	37943	Colistin sulphate	10 µg (disc)	from Antibiotic test
3094	28915	Fosfomycin	50 µg (disc)	from Antibiotic test
3094	17833	Gentamicin	30 µg (disc)	from Antibiotic test
3094	17833	Gentamycin	10 µg (disc)	from Antibiotic test
3094	6472	Lincomycin	15 µg (disc)	from Antibiotic test
3094	63607	Linezolid	10 µg (disc)	from Antibiotic test
3094	71415	Nitrofurantoin	100 µg (disc)	from Antibiotic test
3094	7660	Nystatin	100 Unit	from Antibiotic test
3094	7809	Oxacillin	5 µg (disc)	from Antibiotic test
3094	18208	Penicillin G	6 µg (disc)	from Antibiotic test
3094		Piperacillin/Tazobactam	110 µg (disc)	from Antibiotic test
3094	8309	Polymyxin B	300 Unit	from Antibiotic test
3094	29687	Teicoplanin	30 µg (disc)	from Antibiotic test
3094	9587	Ticarcillin	75 µg (disc)	from Antibiotic test
3094	149836	Tigecycline	15 µg (disc)	from Antibiotic test
3094	28001	Vancomycin	30 µg (disc)	from Antibiotic test

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68369	35581 ChEBI	indole		from API 20NE
117247	35581 ChEBI	indole

Metabolite tests

@ref	Chebi-ID	Metabolite	Indole test
68369	35581 ChEBI	indole	-	from API 20NE

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
117247	alcohol dehydrogenase	-	1.1.1.1
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	-	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
117247	amylase	-
68369	arginine dihydrolase	-	3.5.3.6	from API 20NE
68382	beta-galactosidase	-	3.2.1.23	from API zym
117247	beta-galactosidase	+	3.2.1.23
68382	beta-glucosidase	+	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
117247	caseinase	-	3.4.21.50
3094	catalase	+	1.11.1.6
117247	catalase	+	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
3094	cytochrome-c oxidase	+	1.9.3.1
117247	DNase	-
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
117247	gamma-glutamyltransferase	+	2.3.2.2
117247	gelatinase	-
117247	lecithinase	+
68382	leucine arylamidase	+	3.4.11.1	from API zym
117247	lipase	-
68382	lipase (C 14)	+		from API zym
117247	lysine decarboxylase	+	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	+	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
117247	ornithine decarboxylase	-	4.1.1.17
117247	oxidase	+
117247	protease	-
68382	trypsin	-	3.4.21.4	from API zym
117247	tryptophan deaminase	-
117247	tween esterase	+
117247	urease	-	3.5.1.5
68369	urease	-	3.5.1.5	from API 20NE
68382	valine arylamidase	-		from API zym

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
117247	-	+	+	+	+	+	-	-	-	-	+	+	-	-	-	-	+	+	-	-

API 20NE

@ref	Reduction of nitratesNO3	TRP	GLU_ Ferm	ADH (Arg)	URE	ESC	GEL	PNPG	GLU_ Assim	ARA	MNE	MAN	NAG	MAL	GNT	CAP	ADI	MLT	CIT	PAC	OX
3094	-	-	+	-	-	+/-	-	+	+	+	+	+	+	-	+	+	+	+	+	+	+
3094	-	-	-	-	-	+	-	+	+	+	+	+	+	-	+	+	+	+	+	+	+
3094	-	-	-	-	-	+	-	+	+	+	+	+	+	-	+	+	+	+	+	+	-
3094	-	-	-	-	-	+	-	+	+	+	+	+	+	+/-	+	+	+	+	+	+	+
3094	-	-	-	-	-	+	+	+	+	+	+	+	+	-	+	+	+	+	+	+	+
3094	-	-	-	-	-	-	-	+	+	+	+	+	+	-	+	+	+	+	+	+	+
3094	-	-	-	-	-	+	-	+	+	+	+	+	+	-	+	+	+	+	+	+	not determinedn.d.
3094	-	-	-	-	-	+	-	+	+	+	+	+	+	-	+	+	+	+	+/-	+	not determinedn.d.
3094	-	-	-	-	-	+	+	+	+	+	+	+	+	-	+	+	+	+	+	+	not determinedn.d.
3094	-	-	-	-	-	+	-	+	+	+	+	+	+	-	+	+	+	+	+	+	+
3094	-	-	-	-	-	+/-	-	+	+	+	+	+	+	+/-	+	+	+	+	+	+	+
3094	-	-	-	-	-	+	-	+	+	+	+	+	+	-	+	+	+	+	+	+	+
3094	-	-	-	-	-	-	-	+	+	+	+	+	+	+/-	+	+	+	+	+	+	+

API biotype100

@ref	ControlQ	D-glucose as carbon sourceGLU	D-fructose as carbon sourceFRU	D-galactose as carbon sourceGAL	D-trehalose as carbon sourceTRE	D-mannose as carbon sourceMNE	L-sorbose as carbon sourceSBE	D-melibiose as carbon sourceMEL	sucrose as carbon sourceSAC	D-raffinose as carbon sourceRAF	maltotriose as carbon sourceMTE	maltose as carbon sourceMAL	lactose as carbon sourceLAC	lactulose as carbon sourceLTE	1-O-methyl-beta-galactopyranoside as carbon sourceMbGa	1-O-methyl-alpha-galactopyranoside as carbon sourceMaGa	D-cellobiose as carbon sourceCEL	gentiobiose as carbon sourceGEN	1-O-methyl-beta-D-glucopyranoside as carbon sourceMbGu	esculin as carbon sourceESC	D-ribose as carbon sourceRIB	L-arabinose as carbon sourceARA	D-xylose as carbon sourceXYL	palatinose as carbon sourcePLE	L-rhamnose as carbon sourceRHA	L-fucose as carbon sourceFUC	D-melezitose as carbon sourceMLZ	D-arabitol as carbon sourceDARL	L-arabitol as carbon sourceLARL	xylitol as carbon sourceXLT	dulcitol as carbon sourceDUL	D-tagatose as carbon sourceTAG	glycerol as carbon sourceGLY	myo-inositol as carbon sourceINO	D-mannitol as carbon sourceMAN	maltitol as carbon sourceMTL	D-turanose as carbon sourceTUR	D-sorbitol as carbon sourceSOR	adonitol as carbon sourceADO	hydroxyquinoline-beta-glucuronide as carbon sourceHBG	D-lyxose as carbon sourceLYX	i-erythritol as carbon sourceERY	1-O-methyl-alpha-D-glucoside as carbon sourceMDG	3-O-methyl-D-glucose as carbon source3MDG	D-saccharate as carbon sourceSAT	mucate as carbon sourceMUC	L-tartrate as carbon sourceLTAT	D-tartrate as carbon sourceDTAT	meso-tartrate as carbon sourceMTAT	D-malate as carbon sourceDMLT	L-malate as carbon sourceLMLT	cis-aconitate as carbon sourceCATE	trans-aconitate as carbon sourceTATE	tricarballylate as carbon sourceTTE	citrate as carbon sourceCIT	D-glucuronate as carbon sourceGRT	D-galacturonate as carbon sourceGAT	2-ketogluconate as carbon source2KG	5-ketogluconate as carbon source5KG	tryptophan as carbon sourceTRY	N-acetyl-D-glucosamine as carbon sourceNAG	D-gluconate as carbon sourceGNT	phenylacetate as carbon sourcePAC	protocatechuate as carbon sourcePAT	4-hydroxybenzoate as carbon sourcepOBE	quinate as carbon sourceQAT	gentisate as carbon sourceGTE	3-hydroxybenzoate as carbon sourcemOBE	benzoate as carbon sourceBAT	3-phenylpropionate as carbon sourcePPAT	m-coumarate as carbon sourceCMT	trigonelline as carbon sourceTGE	betaine as carbon sourceBET	putrescine as carbon sourcePCE	4-aminobutyrate as carbon sourceABT	histamine as carbon sourceHIN	DL-lactate as carbon sourceLAT	caprate as carbon sourceCAP	caprylate as carbon sourceCYT	L-histidine as carbon sourceHIS	succinate as carbon sourceSUC	fumarate as carbon sourceFUM	glutarate as carbon sourceGRE	DL-glycerate as carbon sourceGYT	5-aminovalerate as carbon sourceAVT	ethanolamine as carbon sourceETN	tryptamine as carbon sourceTTN	D-glucosamine as carbon sourceGLN	itaconate as carbon sourceITA	3-hydroxybutyrate as carbon source3OBU	L-aspartate as carbon sourceAPT	L-glutamate as carbon sourceGTT	L-proline as carbon sourcePRO	D-alanine as carbon sourceDALA	L-alanine as carbon sourceLALA	L-serine as carbon sourceSER	malonate as carbon sourceMNT	propionate as carbon sourcePROP	L-tyrosine as carbon sourceTYR	2-ketoglutarate as carbon source2KT
117247	not determinedn.d.	+	+	+	+	+	-	-	+	-	-	-	-	-	+	-	+	+	+	+	+	+	+	-	-	+	-	+	+	+	+	+	+	+	+	-	-	+	+	-	+	-	-	-	+	+	+	-	-	+	+	+	+	-	+	+	+	+	+	-	+	+	+	+	+	+	+	+	+	-	-	-	+	+	+	+	+	+	+	-	+	+	+	+	+	+	+	+	-	+	+	+	+	+	+	+	+	+	+	+

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Host	#Plants	#Herbaceous plants (Grass,Crops)
#Host Body-Site	#Plant	#Root (Rhizome)

Isolation

@ref	Sample type
3094	Onion
67770	Onion
117247	Onion

Taxonmaps

69479

Global distribution of 16S sequence U96927 (>99% sequence identity) for Burkholderia from Microbeatlas

Aquatic Samples	564
Soil Samples	1055
Animal Samples	1930
Plant Samples	1505
Total Samples	5054

Interaction and safety

Risk assessment

@ref	Pathogenicity human	Pathogenicity animal	Pathogenicity plant	Biosafety level	Biosafety level comment
3094				2	Risk group (German classification) According to TRBA 466
117247				2	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM609431v1 assembly for Burkholderia cepacia ATCC 25416	complete	GCA_006094315	983594.35		983594	98.24
66792	ASM141149v1 assembly for Burkholderia cepacia ATCC 25416 UCB 717	complete	GCA_001411495		2879882273	983594	98.23
66792	ASM354646v1 assembly for Burkholderia cepacia ATCC 25416	complete	GCA_003546465	983594.32	2912464834	983594	98.14
67770	52223_E01 assembly for Burkholderia cepacia NCTC10743	contig	GCA_900446175	292.148	2916573127	292	75.96
66792	ASM47348v1 assembly for Burkholderia cepacia ATCC 25416	scaffold	GCA_000473485	983594.7	2509276048	983594	70.23
66792	ASM152884v1 assembly for Burkholderia cepacia NBRC 14074	contig	GCA_001528845	292.70	2731957558	292	57.49

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Burkholderia cepacia strain ATCC 25416 16S ribosomal RNA gene, partial sequence	AY728197	687	983594
20218	Burkholderia cepacia gene for 16S rRNA, partial sequence, strain: ATCC 25416 (= EY 645)	D13046	158	983594
20218	Burkholderia cepacia ATCC 25416 strain LMG 1222 16S ribosomal RNA gene, partial sequence	HQ849078	1124	983594
20218	P.cepacia 16S ribosomal RNA, complete cds	M22518	1473	292
20218	Burkholderia cepacia 16S ribosomal RNA gene, partial sequence	U96927	1610	983594
3094	Burkholderia cepacia strain ATCC25416 16S ribosomal RNA gene, partial sequence	AF097530	1462	983594
124043	Burkholderia cepacia gene for 16S rRNA, partial sequence, strain: NBRC 14074.	AB680546	1458	292
124043	Burkholderia cepacia strain LMG 1222 16S ribosomal RNA gene, partial sequence.	AF416381	181	983594
124043	Burkholderia cepacia strain LMG 1222 16S ribosomal RNA gene, partial sequence.	AF495867	333	983594
124043	Burkholderia cepacia strain BCRC 13208 16S-23S ribosomal RNA intergenic spacer, complete sequence.	EU014582	392	292
124043	Burkholderia cepacia ATCC 25416 16S ribosomal RNA gene, partial sequence.	MN420667	857	983594
124043	Burkholderia cepacia ATCC 25416 16S ribosomal RNA gene, partial sequence.	KY435830	907	983594
124043	Burkholderia cepacia strain ATCC 25416 16S ribosomal RNA gene, partial sequence.	KX378342	554	292
124043	Burkholderia cepacia ATCC 25416 16S ribosomal RNA gene, partial sequence.	MN420665	862	983594
124043	Burkholderia cepacia strain LMG 1222 16S ribosomal RNA gene, partial sequence.	EU024171	1313	292
124043	Burkholderia cepacia ATCC 25416 strain LMG 1222 16S ribosomal RNA gene, partial sequence.	PV235382	483	983594
124043	Burkholderia cepacia strain NBRC 14074 16S ribosomal RNA gene, partial sequence.	MZ066514	817	292
124043	Burkholderia cepacia strain NBRC 14074 16S ribosomal RNA gene, partial sequence.	PP528166	917	292
124043	Burkholderia cepacia strain NBRC 14074 16S ribosomal RNA gene, partial sequence.	MZ068095	331	292

GC content

@ref	GC-content (mol%)	Method
3094	67.8	Buoyant density centrifugation (BD)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Burkholderia cepacia ATCC 25416 UCB 717
NCBI: GCA_001411495

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	90.30	no
125439	motility	BacteriaNetⓘ	yes	68.20	no
125439	gram_stain	BacteriaNetⓘ	negative	89.30	no
125439	oxygen_tolerance	BacteriaNetⓘ	aerobe	98.10	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Burkholderia cepacia ATCC 25416 UCB 717
NCBI: GCA_001411495.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	97.95	no
125438	anaerobic	anaerobicⓘ	no	97.37	yes
125438	aerobic	aerobicⓘ	yes	91.31	no
125438	spore-forming	spore-formingⓘ	no	86.65	no
125438	thermophilic	thermophileⓘ	no	98.00	no
125438	flagellated	motile2+ⓘ	yes	83.59	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Identification and validation of intratumoral microbiome associated with sensitization to immune checkpoint inhibitors.	Chen J, Gao Y, Chen Y, Wang Q, Zhang Y, Huang Y, Xian X, Zhou D, Zhou H, Liu R, Zou Y, Zhang W.	Cell Rep Med	10.1016/j.xcrm.2025.102306	2025
	A culture-independent nucleic acid diagnostics method for use in the detection and quantification of Burkholderia cepacia complex contamination in aqueous finished pharmaceutical products.	Duong H, Minogue E, Fullbrook S, Barry T, Reddington K.	PLoS One	10.1371/journal.pone.0303773	2024
	Disrupting quorum sensing as a strategy to inhibit bacterial virulence in human, animal, and plant pathogens.	Gonzales M, Kergaravat B, Jacquet P, Billot R, Grizard D, Chabriere E, Plener L, Daude D.	Pathog Dis	10.1093/femspd/ftae009	2024
	Screening of natural phenazine producers for electroactivity in bioelectrochemical systems.	Franco A, Elbahnasy M, Rosenbaum MA.	Microb Biotechnol	10.1111/1751-7915.14199	2023
	Assessment of microbial activity by CO₂ production during heating oil storage.	Surger MJ, Blank LM.	Eng Life Sci	10.1002/elsc.202100144	2022
	Evaluating microbial contaminations of alternative heating oils.	Surger MJ, Mayer K, Shivaram K, Stibany F, Plum W, Schaffer A, Eiden S, Blank LM.	Eng Life Sci	10.1002/elsc.202300010	2023
	Species-specific viability analysis of Pseudomonas aeruginosa, Burkholderia cepacia and Staphylococcus aureus in mixed culture by flow cytometry.	Ruger M, Ackermann M, Reichl U.	BMC Microbiol	10.1186/1471-2180-14-56	2014
Phylogeny	Evaluation of matrix-assisted laser desorption ionization-time-of-flight mass spectrometry in comparison to 16S rRNA gene sequencing for species identification of nonfermenting bacteria.	Mellmann A, Cloud J, Maier T, Keckevoet U, Ramminger I, Iwen P, Dunn J, Hall G, Wilson D, Lasala P, Kostrzewa M, Harmsen D.	J Clin Microbiol	10.1128/jcm.00157-08	2008
	Double labeling of oligonucleotide probes for fluorescence in situ hybridization (DOPE-FISH) improves signal intensity and increases rRNA accessibility.	Stoecker K, Dorninger C, Daims H, Wagner M.	Appl Environ Microbiol	10.1128/aem.02456-09	2010
	Filling gaps in bacterial catabolic pathways with computation and high-throughput genetics.	Price MN, Deutschbauer AM, Arkin AP.	PLoS Genet	10.1371/journal.pgen.1010156	2022
Enzymology	Use of a Western blot technique for the serodiagnosis of glanders.	Elschner MC, Scholz HC, Melzer F, Saqib M, Marten P, Rassbach A, Dietzsch M, Schmoock G, de Assis Santana VL, de Souza MM, Wernery R, Wernery U, Neubauer H.	BMC Vet Res	10.1186/1746-6148-7-4	2011
	Pentaplexed quantitative real-time PCR assay for the simultaneous detection and quantification of botulinum neurotoxin-producing clostridia in food and clinical samples.	Kirchner S, Kramer KM, Schulze M, Pauly D, Jacob D, Gessler F, Nitsche A, Dorner BG, Dorner MB.	Appl Environ Microbiol	10.1128/aem.02490-09	2010
	Characterization of two novel dye-decolorizing peroxidases from Burkholderia cepacia for accelerating lignin utilization in Pseudomonas putida	He F, Ma R, Zeng J, Zhang Y, Liu Y, Gong C, Yu X.	Industrial crops and products.		2025
Enzymology	Enhancing the destruction of Burkholderia cepacia biofilm on stainless steel coupons by combining matrix-degrading enzymes with antimicrobials.	Gharat YP, Abdelhamid AG, Yousef AE.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1662291	2025
	Efficacy of Residual Ozone on Surrogate Microorganisms for Waterborne Pathogens in Bottled Water.	Schwaner WR, Kumar S, Thippareddi H.	J Food Prot	10.1016/j.jfp.2025.100515	2025
	Bioactive Phenolic Compounds from Rambutan (Nephelium lappaceum L.) Shell: Encapsulation, Structural Stability, and Multifunctional Activities.	Barba-Ostria C, Lopez O, Debut A, Mayorga-Ramos A, Zuniga-Miranda J, Coyago-Cruz E, Gonzalez-Pastor R, Cartuchi K, Viteri A, Penaherrera-Pazmino AB, Guaman LP.	Int J Mol Sci	10.3390/ijms262210859	2025
	In vitro and in vivo activity of cefiderocol against Achromobacter spp. and Burkholderia cepacia complex, including carbapenem-non-susceptible isolates.	Takemura M, Nakamura R, Ota M, Nakai R, Sahm DF, Hackel MA, Yamano Y.	Antimicrob Agents Chemother	10.1128/aac.00346-23	2023
	Susceptibility and resistance of Gram-negative bacteria to a novel antimicrobial agent TGV-49.	Tetz VV, Kardava KM, Vecherkovskaya MF, Leyn SA, Elane ML, Osterman AL, Tetz GV.	Front Antibiot	10.3389/frabi.2025.1615821	2025
	Development of a duplex droplet digital PCR assay for the detection of Burkholderia cepacia complex and Stenotrophomonas maltophilia in bloodstream infections.	Liu C, He Z, Kong M, Jin D.	Microbiol Spectr	10.1128/spectrum.03569-23	2024
	Tracking melioidosis in Iran: Utilizing abattoir-based surveillance as a One Health approach.	Mosavari N, Bashashati M, Dehghanpour M, Abdolvand M, Heshmatinia F, Sabouri F, Dashtipour S, Hosseini SM, Najafpour R, Baradaran-Seyed Z.	Vet Med Sci	10.1002/vms3.1503	2024
	Optimizing neutralization strategies for microbial testing of non-sterile pharmaceutical finished products with challenging method suitability.	Eldemerdash A, Ewaisha R, Alseqely M, Shehat MG.	BMC Microbiol	10.1186/s12866-025-04456-9	2025
Genetics	Genomes of the Bacterial Endosymbionts of Carrot Psyllid Trioza apicalis Suggest Complementary Biosynthetic Capabilities.	Thompson S, Wang J, Schott T, Nissinen R, Haapalainen M.	Curr Microbiol	10.1007/s00284-025-04119-y	2025
	Soleris® Automated System for the Rapid Detection of Burkholderia cepacia Complex in Cosmetic Products.	Zhang L, Tolan J, Lavigne N, Montei C, Donofrio R, Biswas P.	J AOAC Int	10.1093/jaoacint/qsac109	2022
Genetics	A Wild Rice Rhizobacterium Burkholderiacepacia BRDJ Enhances Nitrogen Use Efficiency in Rice.	Li Z, Henawy AR, Halema AA, Fan Q, Duanmu D, Huang R.	Int J Mol Sci	10.3390/ijms231810769	2022
	Latest Update on Outer Membrane Vesicles and Their Role in Horizontal Gene Transfer: A Mini-Review.	Marinacci B, Krzyzek P, Pellegrini B, Turacchio G, Grande R.	Membranes (Basel)	10.3390/membranes13110860	2023
	Green Synthesis of Silver Oxide Nanoparticles from Mauritia flexuosa Fruit Extract: Characterization and Bioactivity Assessment.	Zuniga-Miranda J, Vaca-Vega D, Vizuete K, Carrera-Pacheco SE, Gonzalez-Pastor R, Heredia-Moya J, Mayorga-Ramos A, Barba-Ostria C, Coyago-Cruz E, Debut A, Guaman LP.	Nanomaterials (Basel)	10.3390/nano14231875	2024
	Phenotype-Guided Comparative Genomics Identifies the Complete Transport Pathway of the Antimicrobial Lasso Peptide Ubonodin in Burkholderia.	Do T, Thokkadam A, Leach R, Link AJ.	ACS Chem Biol	10.1021/acschembio.2c00420	2022
	Prophylactic phage biocontrol prevents Burkholderia gladioli infection in a quantitative ex planta model of bacterial virulence.	Lauman P, Dennis JJ.	Appl Environ Microbiol	10.1128/aem.01317-24	2024
	Cefoperazone rapidly and sensitive quantitative assessment via a validated RP-HPLC method for different dosage forms, in-use stability, and antimicrobial activities.	Al-Hakkani MF, Ahmed N, Abbas AA, Hassan MHA.	BMC Chem	10.1186/s13065-023-00989-0	2023
Genetics	Metagenome-inspired libraries to engineer phage M13 for targeted killing of Gram-negative bacterial species.	Yang Y, Kang D, Mihalache B, Vexler S, Jain S, Peng H, Annabi N, Yang S, Chen IA.	Nucleic Acids Res	10.1093/nar/gkaf984	2025
	A Synthetic Phage-Peptide Conjugate as a Potent Antibacterial Agent for Pseudomonas aeruginosa Infections.	Yang Y, Vexler S, Jordan MC, Abbondante S, Kang D, Peng H, Marshall M, Naini BV, Jain S, Lai YC, Annabi N, Roos KP, Pearlman E, Chen IA.	ACS Cent Sci	10.1021/acscentsci.5c00562	2025
Genetics	Comparative Genome Analyses Provide Insight into the Antimicrobial Activity of Endophytic Burkholderia.	Jia J, Lu SE.	Microorganisms	10.3390/microorganisms12010100	2024
	Exploring the Antimicrobial Properties of 99 Natural Flavour and Fragrance Raw Materials against Pathogenic Bacteria: A Comparative Study with Antibiotics.	Bacinska Z, Baberowska K, Surowiak AK, Balcerzak L, Strub DJ.	Plants (Basel)	10.3390/plants12213777	2023
	Enantioselective synthesis of a chiral intermediate of himbacine analogs by Burkholderia cepacia lipase A	Chen Y, Gao F, Zheng G, Gao S.	Biotechnol Lett		2020
	Development and evaluation of a colorimetric LAMP-based biosensor for rapid detection of a nosocomial infection agent, Citrobacter freundii.	Mollasalehi H, Esmaili F, Minai-Tehrani D.	Sci Rep	10.1038/s41598-023-49329-1	2023
	Discovery, Characterization, and Bioactivity of the Achromonodins: Lasso Peptides Encoded by Achromobacter.	Carson DV, Zhang Y, So L, Cheung-Lee WL, Cartagena AJ, Darst SA, Link AJ.	J Nat Prod	10.1021/acs.jnatprod.3c00536	2023
	A novel ready-to-use loop-mediated isothermal amplification (LAMP) method for detection of Burkholderia mallei and B. pseudomallei.	Nakase M, Thapa J, Batbaatar V, Khurtsbaatar O, Enkhtuul B, Unenbat J, Lkham B, Fujita S, Koshikawa A, Tuanyok A, Saechan V, Higashi H, Hayashida K, Suzuki Y, Nakajima C, Kimura T.	BMC Microbiol	10.1186/s12866-024-03737-z	2025
	Exploring the Multifaceted Biological Activities of Anthocyanins Isolated from Two Andean Berries.	Barba-Ostria C, Carrera-Pacheco SE, Gonzalez-Pastor R, Zuniga-Miranda J, Mayorga-Ramos A, Tejera E, Guaman LP.	Foods	10.3390/foods13162625	2024
	Discovery of a Novel Lineage Burkholderia cepacia ST 1870 Endophytically Isolated from Medicinal Polygala paniculata Which Shows Potent In Vitro Antileishmanial and Antimicrobial Effects.	de Paula Nogueira Cruz F, Ferreira de Paula A, Nogueira CT, Marques de Andrade PH, Borges LM, Lacava PT, Baratella da Cunha Camargo IL, Anibal FF, Paiva de Sousa C.	Int J Microbiol	10.1155/2021/6618559	2021
	Burkholderia cepacia complex outbreak originating from contaminated wash gloves.	Lo Priore E, Bernasconi S, Schlotterbeck H, Seth-Smith HM, Egli A, Martinetti G, Balmelli C.	Infect Prev Pract	10.1016/j.infpip.2020.100039	2020
	Phytochemical Composition and Biological Properties of Macleania rupestris Fruit Extract: Insights into Its Antimicrobial and Antioxidant Activity.	Mayorga-Ramos A, Zuniga-Miranda J, Coyago-Cruz E, Heredia-Moya J, Guaman-Bautista J, Guaman LP.	Antioxidants (Basel)	10.3390/antiox14040394	2025
	Oleic Acid Facilitates Cd Excretion by Increasing the Abundance of Burkholderia in Cd-Exposed Mice.	Fang Z, Chen Y, Li Y, Sun L, Deng Q, Wang J, Gooneratne R.	Int J Mol Sci	10.3390/ijms232314718	2022
	Cell envelope structural and functional contributions to antibiotic resistance in Burkholderia cenocepacia.	Hogan AM, Motnenko A, Rahman ASMZ, Cardona ST.	J Bacteriol	10.1128/jb.00441-23	2024
Metabolism	Presence of the Hmq System and Production of 4-Hydroxy-3-Methyl-2-Alkylquinolines Are Heterogeneously Distributed between Burkholderia cepacia Complex Species and More Prevalent among Environmental than Clinical Isolates.	Coulon PML, Zlosnik JEA, Deziel E.	Microbiol Spectr	10.1128/spectrum.00127-21	2021
	Identification of Coumarins and Antimicrobial Potential of Ethanolic Extracts of Dipteryx odorata and Dipteryx punctata.	Sousa BCM, Castro SP, Lourido KA, Kasper AAM, Paulino GDS, Delarmelina C, Duarte MCT, Sartoratto A, Vieira TA, Lustosa DC, Barata LES.	Molecules	10.3390/molecules27185837	2022
Genetics	Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018.	Becker SL, Berger FK, Feldner SK, Karliova I, Haber M, Mellmann A, Schafers HJ, Gartner B.	Euro Surveill	10.2807/1560-7917.es.2018.23.42.1800540	2018
	Draft Genome Sequence of Pseudomonas sp. Strain FEN, Isolated from the Fe- and Organic Matter-Rich Schlöppnerbrunnen Fen.	Cooper RE, Wegner CE, Kusel K.	Microbiol Resour Announc	10.1128/mra.01017-20	2021
	Reverse Vaccinology and Immunoinformatic Assisted Designing of a Multi-Epitopes Based Vaccine Against Nosocomial Burkholderia cepacia.	Alsowayeh N, Albutti A, Al-Shouli ST.	Front Microbiol	10.3389/fmicb.2022.929400	2022
	Evolution of PqsE as a Pseudomonas aeruginosa-specific regulator of LuxR-type receptors: insights from Pseudomonas and Burkholderia.	Mallery CP, Simanek KA, Pope AN, Paczkowski JE.	mBio	10.1128/mbio.00646-25	2025
	Draft Genome Sequence of Burkholderia cepacia ATCC 17759, a Polyhydroxybutyrate-Co-Valerate Copolymer-Producing Bacterium.	Crooks C, Palmer JM, Lindner DL.	Genome Announc	10.1128/genomea.00348-18	2018
Metabolism	Functional Analysis of Phenazine Biosynthesis Genes in Burkholderia spp.	Hendry S, Steinke S, Wittstein K, Stadler M, Harmrolfs K, Adewunmi Y, Sahukhal G, Elasri M, Thomashow L, Weller D, Mavrodi O, Blankenfeldt W, Mavrodi D.	Appl Environ Microbiol	10.1128/aem.02348-20	2021
	A multiplex Taqman PCR assay for MRSA detection from whole blood.	Duraiswamy S, Agarwalla S, Lok KS, Tse YY, Wu R, Wang Z.	PLoS One	10.1371/journal.pone.0294782	2023
	Synthesis of soluble melanin nanoparticles under acidic conditions using Burkholderia cepacia tyrosinase and their characterization.	Kim H, Lee UJ, Song H, Lee J, Song WS, Noh H, Kang MH, Kim BS, Park J, Hwang NS, Kim BG.	RSC Adv	10.1039/d2ra01276f	2022
	Pilot Testing of the "Turbidimeter", a Simple, Universal Reader Intended to Complement and Enhance Bacterial Growth Detection in Manual Blood Culture Systems in Low-Resource Settings.	Barbe B, Corsmit E, Jans J, Kaur K, Baets R, Jacobs J, Hardy L.	Diagnostics (Basel)	10.3390/diagnostics12030615	2022
Pathogenicity	Activity of Aerosolized Levofloxacin against Burkholderia cepacia in a Mouse Model of Chronic Lung Infection.	Sabet M, Griffith DC.	Antimicrob Agents Chemother	10.1128/aac.01988-19	2020
	Rapid, Low-Complexity, Simultaneous Bacterial Group Identification and Antimicrobial Susceptibility Testing Performed Directly on Positive Blood Culture Bottles Using Chromogenic Agar.	Robberts FJL, Owusu-Ofori A, Oduro G, Gyampomah TK, Marles N, Fox AT, Chenoweth JG, Schully KL, Clark DV.	Am J Trop Med Hyg	10.4269/ajtmh.22-0278	2022
Pathogenicity	In Vitro Activity of a Novel Glycopolymer against Biofilms of Burkholderia cepacia Complex Cystic Fibrosis Clinical Isolates.	Narayanaswamy VP, Duncan AP, LiPuma JJ, Wiesmann WP, Baker SM, Townsend SM.	Antimicrob Agents Chemother	10.1128/aac.00498-19	2019
Genetics	A Phylogeny-Informed Proteomics Approach for Species Identification within the Burkholderia cepacia Complex.	Wang H, Cisse OH, Bolig T, Drake SK, Chen Y, Strich JR, Youn JH, Okoro U, Rosenberg AZ, Sun J, LiPuma JJ, Suffredini AF, Dekker JP.	J Clin Microbiol	10.1128/jcm.01741-20	2020
	Genome-based taxonomy of Burkholderia sensu lato: Distinguishing closely related species.	Bach E, Volpiano CG, Sant'Anna FH, Passaglia LMP.	Genet Mol Biol	10.1590/1678-4685-gmb-2023-0122	2023
	Detection of Escherichia coli, Pseudomonas aeruginosa, Salmonella paratyphoid B, and Shigella dysentery in live Bacillus licheniformis products using propidium monoazide-real-time-quantitative polymerase chain reaction.	Zheng X, Wang Y, Gong W, Cai Q, Li J, Wu J.	Front Microbiol	10.3389/fmicb.2022.996794	2022
Enzymology	A Selective, Dual Emission beta-Alanine Aminopeptidase Activated Fluorescent Probe for the Detection of Pseudomonas aeruginosa, Burkholderia cepacia, and Serratia marcescens.	Varadi L, Najib EY, Hibbs DE, Perry JD, Groundwater PW.	Molecules	10.3390/molecules24193550	2019
Pathogenicity	Discovery of Ubonodin, an Antimicrobial Lasso Peptide Active against Members of the Burkholderia cepacia Complex.	Cheung-Lee WL, Parry ME, Zong C, Cartagena AJ, Darst SA, Connell ND, Russo R, Link AJ.	Chembiochem	10.1002/cbic.201900707	2020
	Peptidorhamnomannans From Scedosporium and Lomentospora Species Display Microbicidal Activity Against Bacteria Commonly Present in Cystic Fibrosis Patients.	de Oliveira EB, Xisto MIDDS, Rollin-Pinheiro R, Rochetti VP, Barreto-Bergter E.	Front Cell Infect Microbiol	10.3389/fcimb.2020.598823	2020
Phylogeny	Microbial Communities in the Extraradicular and Intraradicular Infections Associated With Persistent Apical Periodontitis.	Sun X, Yang Z, Nie Y, Hou B.	Front Cell Infect Microbiol	10.3389/fcimb.2021.798367	2021
	An Alternative Microbiological Validation for an Online Water Bioburden Analyzer.	Venhuizen OL, Martindale CE, Liew FJ, Cannon J, Samanta A, Scaramozzino MJ.	J AOAC Int	10.1093/jaoacint/qsae050	2024
Phylogeny	Genome-based classification of Burkholderia cepacia complex provides new insight into its taxonomic status.	Jin Y, Zhou J, Zhou J, Hu M, Zhang Q, Kong N, Ren H, Liang L, Yue J.	Biol Direct	10.1186/s13062-020-0258-5	2020
Pathogenicity	Cationic Intrinsically Disordered Antimicrobial Peptides (CIDAMPs) Represent a New Paradigm of Innate Defense with a Potential for Novel Anti-Infectives.	Latendorf T, Gerstel U, Wu Z, Bartels J, Becker A, Tholey A, Schroder JM.	Sci Rep	10.1038/s41598-019-39219-w	2019
	Polysaccharides Produced by Plant Growth-Promoting Rhizobacteria Strain Burkholderia sp. BK01 Enhance Salt Stress Tolerance to Arabidopsis thaliana.	Chen E, Yang C, Tao W, Li S.	Polymers (Basel)	10.3390/polym16010145	2024
Genetics	Microbial isolation and characterization from two flex lines from the urine processor assembly onboard the international space station.	Nguyen HN, Sharp GM, Stahl-Rommel S, Velez Justiniano YA, Castro CL, Nelman-Gonzalez M, O'Rourke A, Lee MD, Williamson J, McCool C, Crucian B, Clark KW, Jain M, Castro-Wallace SL.	Biofilm	10.1016/j.bioflm.2023.100108	2023
	Phenazines and toxoflavin act as interspecies modulators of resilience to diverse antibiotics.	Meirelles LA, Newman DK.	Mol Microbiol	10.1111/mmi.14915	2022
Genetics	Genome sequencing of Burkholderia contaminans LTEB11 reveals a lipolytic arsenal of biotechnological interest.	Alnoch RC, Cardoso RLA, Guizelini D, Balsanelli E, Tadra-Sfeir MZ, de Oliveira Pedrosa F, Sassaki GL, Cruz LM, Mitchell DA, de Souza EM, Krieger N, Muller-Santos M.	Braz J Microbiol	10.1007/s42770-019-00076-4	2019
	New perspectives on an old grouping: The genomic and phenotypic variability of Oxalobacter formigenes and the implications for calcium oxalate stone prevention.	Chmiel JA, Carr C, Stuivenberg GA, Venema R, Chanyi RM, Al KF, Giguere D, Say H, Akouris PP, Dominguez Romero SA, Kwong A, Tai V, Koval SF, Razvi H, Bjazevic J, Burton JP.	Front Microbiol	10.3389/fmicb.2022.1011102	2022
	In silico design and validation of a highly degenerate primer pair: a systematic approach.	Chukwuemeka PO, Umar HI, Olukunle OF, Oretade OM, Olowosoke CB, Akinsola EO, Elabiyi MO, Kurmi UG, Eigbe JO, Oyelere BR, Isunu LE, Oretade OJ.	J Genet Eng Biotechnol	10.1186/s43141-020-00086-y	2020
Enzymology	Novel glycopolymer sensitizes Burkholderia cepacia complex isolates from cystic fibrosis patients to tobramycin and meropenem.	Narayanaswamy VP, Giatpaiboon S, Baker SM, Wiesmann WP, LiPuma JJ, Townsend SM.	PLoS One	10.1371/journal.pone.0179776	2017
	Influence of relevant cystic fibrosis bacteria on Scedosporium apiospermum and Scedosporium boydii growth and viability.	Marques AJ, Rollin-Pinheiro R, Xisto MIDDS, Dos Santos ALS, Barreto-Bergter E, Liporagi-Lopes LC.	Braz J Microbiol	10.1007/s42770-020-00415-w	2021
	Outer Membrane Vesicles Derived from Klebsiella pneumoniae Are a Driving Force for Horizontal Gene Transfer.	Dell'Annunziata F, Dell'Aversana C, Doti N, Donadio G, Dal Piaz F, Izzo V, De Filippis A, Galdiero M, Altucci L, Boccia G, Galdiero M, Folliero V, Franci G.	Int J Mol Sci	10.3390/ijms22168732	2021
	Genomics of an endemic cystic fibrosis Burkholderia multivorans strain reveals low within-patient evolution but high between-patient diversity.	Lood C, Peeters C, Lamy-Besnier Q, Wagemans J, De Vos D, Proesmans M, Pirnay JP, Echahidi F, Pierard D, Thimmesch M, Boeras A, Lagrou K, De Canck E, De Wachter E, van Noort V, Lavigne R, Vandamme P.	PLoS Pathog	10.1371/journal.ppat.1009418	2021
Phylogeny	Molecular Characterization of Bacteria, Detection of Enterotoxin Genes, and Screening of Antibiotic Susceptibility Patterns in Traditionally Processed Meat Products of Sikkim, India.	Bhutia MO, Thapa N, Tamang JP.	Front Microbiol	10.3389/fmicb.2020.599606	2020
	An inventory of early branch points in microbial phosphonate biosynthesis.	Li S, Horsman GP.	Microb Genom	10.1099/mgen.0.000781	2022
	13-(2-Methylbenzyl) Berberine Is a More Potent Inhibitor of MexXY-Dependent Aminoglycoside Resistance than Berberine.	Kotani K, Matsumura M, Morita Y, Tomida J, Kutsuna R, Nishino K, Yasuike S, Kawamura Y.	Antibiotics (Basel)	10.3390/antibiotics8040212	2019
	Evaluation of reverse transcriptase-polymerase spiral reaction assay for rapid and sensitive detection of severe acute respiratory syndrome coronavirus 2.	Prerana S, Ashwini P, Anupama KP, Prajna VS, Prithvisagar KS, Nayak A, Rai P, Rohit A, Karunasagar I, Karunasagar I, Maiti B.	Clin Chim Acta	10.1016/j.cca.2022.12.009	2023
	Efficient Production of Broad-Spectrum Antimicrobials by Paenibacillus polymyxa OSY-EC Using Acid Whey-Based Medium and Novel Antimicrobial Concentration Approach.	Abdelhamid AG, Campbell EP, Hawkins Z, Yousef AE.	Front Bioeng Biotechnol	10.3389/fbioe.2022.869778	2022
Proteome	Identification of Microorganisms by Liquid Chromatography-Mass Spectrometry (LC-MS¹) and in Silico Peptide Mass Libraries.	Lasch P, Schneider A, Blumenscheit C, Doellinger J.	Mol Cell Proteomics	10.1074/mcp.tir120.002061	2020
	Affordable blood culture systems from China: in vitro evaluation for use in resource-limited settings.	Hardy L, Vermoesen T, Genbrugge E, Natale A, Franquesa C, Gleeson B, Ferreyra C, Dailey P, Jacobs J.	EBioMedicine	10.1016/j.ebiom.2024.105004	2024
Enzymology	Characterization of Two Antimicrobial Peptides from Antarctic Fishes (Notothenia coriiceps and Parachaenichthys charcoti).	Shin SC, Ahn IH, Ahn DH, Lee YM, Lee J, Lee JH, Kim HW, Park H.	PLoS One	10.1371/journal.pone.0170821	2017
	Burkholderia cepacia Complex Contact-Dependent Growth Inhibition Systems Mediate Interbacterial Competition.	Myers-Morales T, Oates AE, Byrd MS, Garcia EC.	J Bacteriol	10.1128/jb.00012-19	2019
Metabolism	Synergy between Active Efflux and Outer Membrane Diffusion Defines Rules of Antibiotic Permeation into Gram-Negative Bacteria.	Krishnamoorthy G, Leus IV, Weeks JW, Wolloscheck D, Rybenkov VV, Zgurskaya HI.	mBio	10.1128/mbio.01172-17	2017
	Characterization of respiratory microbial dysbiosis in hospitalized COVID-19 patients.	Zhong H, Wang Y, Shi Z, Zhang L, Ren H, He W, Zhang Z, Zhu A, Zhao J, Xiao F, Yang F, Liang T, Ye F, Zhong B, Ruan S, Gan M, Zhu J, Li F, Li F, Wang D, Li J, Ren P, Zhu S, Yang H, Wang J, Kristiansen K, Tun HM, Chen W, Zhong N, Xu X, Li YM, Li J, Zhao J.	Cell Discov	10.1038/s41421-021-00257-2	2021
Genetics	Burkholderia stabilis outbreak associated with contaminated commercially-available washing gloves, Switzerland, May 2015 to August 2016.	Sommerstein R, Fuhrer U, Lo Priore E, Casanova C, Meinel DM, Seth-Smith HM, Kronenberg A, Anresis, Koch D, Senn L, Widmer AF, Egli A, Marschall J, Swissnoso.	Euro Surveill	10.2807/1560-7917.es.2017.22.49.17-00213	2017
	The Isolation and Characterization of a Broad Host Range Bcep22-like Podovirus JC1.	Davis CM, Ruest MK, Cole JH, Dennis JJ.	Viruses	10.3390/v14050938	2022
Pathogenicity	Screening a mushroom extract library for activity against Acinetobacter baumannii and Burkholderia cepacia and the identification of a compound with anti-Burkholderia activity.	Schwan WR, Dunek C, Gebhardt M, Engelbrecht K, Klett T, Monte A, Toce J, Rott M, Volk TJ, LiPuma JJ, Liu XT, McKelvey R.	Ann Clin Microbiol Antimicrob	10.1186/1476-0711-9-4	2010
Genetics	A Novel Inducible Prophage from Burkholderia Vietnamiensis G4 is Widely Distributed across the Species and Has Lytic Activity against Pathogenic Burkholderia.	Weiser R, Yap ZL, Otter A, Jones BV, Salvage J, Parkhill J, Mahenthiralingam E.	Viruses	10.3390/v12060601	2020
	C-Terminal 1-Aminoethyltetrazole-Containing Oligopeptides as Novel Alanine Racemase Inhibitors.	Kondacs LA, Orenga S, Anderson RJ, Marrs ECL, Perry JD, Gray M.	Molecules	10.3390/molecules25061315	2020
Metabolism	Distinct colicin M-like bacteriocin-immunity pairs in Burkholderia.	Ghequire MG, De Mot R.	Sci Rep	10.1038/srep17368	2015
	Synthesis, Physicochemical Characterization using a Facile Validated HPLC Quantitation Analysis Method of 4-Chloro-phenylcarbamoyl-methyl Ciprofloxacin and Its Biological Investigations.	Al-Hakkani MF, Ahmed N, Abbas AA, Hassan MHA, Aziz HA, Elshamsy AM, Khalifa HO, Abdelshakour MA, Saddik MS, Elsayed MMA, Sabet MA, El-Mokhtar MA, Alsehli M, Amin MS, Abu-Dief AM, Mohammed HHH.	Int J Mol Sci	10.3390/ijms241914818	2023
	Phenotypic and genotypic characterization of phosphate solubilizing bacteria and their efficiency on the growth of maize.	Pande A, Pandey P, Mehra S, Singh M, Kaushik S.	J Genet Eng Biotechnol	10.1016/j.jgeb.2017.06.005	2017
	Three Distinct Contact-Dependent Growth Inhibition Systems Mediate Interbacterial Competition by the Cystic Fibrosis Pathogen Burkholderia dolosa.	Perault AI, Cotter PA.	J Bacteriol	10.1128/jb.00428-18	2018
	The afc antifungal activity cluster, which is under tight regulatory control of ShvR, is essential for transition from intracellular persistence of Burkholderia cenocepacia to acute pro-inflammatory infection.	Gomes MC, Tasrini Y, Subramoni S, Agnoli K, Feliciano JR, Eberl L, Sokol P, O'Callaghan D, Vergunst AC.	PLoS Pathog	10.1371/journal.ppat.1007473	2018
	Bacterial defenses against a natural antibiotic promote collateral resilience to clinical antibiotics.	Meirelles LA, Perry EK, Bergkessel M, Newman DK.	PLoS Biol	10.1371/journal.pbio.3001093	2021
	Post-harvest cleaning, sanitization, and microbial monitoring of soilless nutrient delivery systems for sustainable space crop production.	Curry AB, Spern CJ, Khodadad CLM, Hummerick ME, Spencer LE, Torres J, Finn JR, Gooden JL, Monje O.	Front Plant Sci	10.3389/fpls.2024.1308150	2024
Metabolism	A Single Human V_H-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the Blood.	Sangesland M, Yousif AS, Ronsard L, Kazer SW, Zhu AL, Gatter GJ, Hayward MR, Barnes RM, Quirindongo-Crespo M, Rohrer D, Lonberg N, Kwon D, Shalek AK, Lingwood D.	Cell Rep	10.1016/j.celrep.2020.108065	2020
	Polyphenol-Hydroxylating Tyrosinase Activity under Acidic pH Enables Efficient Synthesis of Plant Catechols and Gallols.	Song H, Lee PG, Kim H, Lee UJ, Lee SH, Kim J, Kim BG.	Microorganisms	10.3390/microorganisms9091866	2021
Phylogeny	Development of a New Semi-Selective Lysine-Ornithine-Mannitol-Arginine-Charcoal Medium for the Isolation of Pantoea Species from Environmental Sources in Japan.	Kuranishi T, Sekiguchi JI, Yanagisawa I, Akiwa M, Tokuno Y.	Microbes Environ	10.1264/jsme2.me18128	2019
	Whole genome sequencing enables the characterization of BurI, a LuxI homologue of Burkholderia cepacia strain GG4.	How KY, Hong KW, Chan KG.	PeerJ	10.7717/peerj.1117	2015
Pathogenicity	Garlic revisited: antimicrobial activity of allicin-containing garlic extracts against Burkholderia cepacia complex.	Wallock-Richards D, Doherty CJ, Doherty L, Clarke DJ, Place M, Govan JR, Campopiano DJ.	PLoS One	10.1371/journal.pone.0112726	2014
Metabolism	Burkholderia as a Source of Natural Products.	Kunakom S, Eustaquio AS.	J Nat Prod	10.1021/acs.jnatprod.8b01068	2019
Metabolism	Chelation of Membrane-Bound Cations by Extracellular DNA Activates the Type VI Secretion System in Pseudomonas aeruginosa.	Wilton M, Wong MJQ, Tang L, Liang X, Moore R, Parkins MD, Lewenza S, Dong TG.	Infect Immun	10.1128/iai.00233-16	2016
	Surfing in the storm: how Paraburkholderia xenovorans thrives under stress during biodegradation of toxic aromatic compounds and other stressors.	Mendez V, Sepulveda M, Izquierdo-Fiallo K, Macaya CC, Esparza T, Baez-Matus X, Duran RE, Levican G, Seeger M.	FEMS Microbiol Rev	10.1093/femsre/fuaf021	2025
Enzymology	Regulator LdhR and d-Lactate Dehydrogenase LdhA of Burkholderia multivorans Play Roles in Carbon Overflow and in Planktonic Cellular Aggregate Formation.	Silva IN, Ramires MJ, Azevedo LA, Guerreiro AR, Tavares AC, Becker JD, Moreira LM.	Appl Environ Microbiol	10.1128/aem.01343-17	2017
Metabolism	Iron acquisition in the cystic fibrosis lung and potential for novel therapeutic strategies.	Tyrrell J, Callaghan M.	Microbiology (Reading)	10.1099/mic.0.000220	2016
	Effect of Graphene Oxide on the Properties of Poly(3-Hydroxybutyrate-co-3-Hydroxyhexanoate).	Diez-Pascual AM.	Polymers (Basel)	10.3390/polym13142233	2021
Enzymology	Development and clinical validation of a droplet digital PCR assay for detecting Acinetobacter baumannii and Klebsiella pneumoniae in patients with suspected bloodstream infections.	Zheng Y, Jin J, Shao Z, Liu J, Zhang R, Sun R, Hu B.	Microbiologyopen	10.1002/mbo3.1247	2021
	Comparison of Mast Burkholderia Cepacia, Ashdown + Gentamicin, and Burkholderia Pseudomallei Selective Agar for the Selective Growth of Burkholderia Spp.	Edler C, Derschum H, Kohler M, Neubauer H, Frickmann H, Hagen RM.	Eur J Microbiol Immunol (Bp)	10.1556/1886.2016.00037	2017
Enzymology	Rubus rosaefolius extract as a natural preservative candidate in topical formulations.	Ostrosky EA, Marcondes EM, Nishikawa Sde O, Lopes PS, Varca GH, Pinto Tde J, Consiglieri TV, Baby AR, Velasco MV, Kaneko TM.	AAPS PharmSciTech	10.1208/s12249-011-9635-9	2011
Metabolism	Burkholderia contaminans Biofilm Regulating Operon and Its Distribution in Bacterial Genomes.	Voronina OL, Kunda MS, Ryzhova NN, Aksenova EI, Semenov AN, Romanova YM, Gintsburg AL.	Biomed Res Int	10.1155/2016/6560534	2016
Pathogenicity	The contribution of antibiotic resistance mechanisms in clinical Burkholderia cepacia complex isolates: an emphasis on efflux pump activity.	Tseng SP, Tsai WC, Liang CY, Lin YS, Huang JW, Chang CY, Tyan YC, Lu PL.	PLoS One	10.1371/journal.pone.0104986	2014
Phylogeny	Environmental Burkholderia cepacia complex isolates in human infections.	Baldwin A, Mahenthiralingam E, Drevinek P, Vandamme P, Govan JR, Waine DJ, LiPuma JJ, Chiarini L, Dalmastri C, Henry DA, Speert DP, Honeybourne D, Maiden MC, Dowson CG.	Emerg Infect Dis	10.3201/eid1303.060403	2007
	Genetic and Pathogenic Characterization of Bacterial Wilt Pathogen, Ralstonia pseudosolanacearum (Ralstonia solanacearum Phylotype I), on Roses in Korea.	Lee I, Kim YS, Kim JW, Park DH.	Plant Pathol J	10.5423/ppj.oa.06.2020.0095	2020
Enzymology	Identification and Characterization of Burkholderia pseudomallei from Localized Pyogenic Infections in Eastern India: A Clinico-Microbiological Study.	Purushotham P, Mohanty S, Chappity P, Mishra TS, Mahapatra A.	Am J Trop Med Hyg	10.4269/ajtmh.20-1386	2021
	Potential for and Distribution of Enzymatic Biodegradation of Polystyrene by Environmental Microorganisms.	Hou L, Majumder EL.	Materials (Basel)	10.3390/ma14030503	2021
	Drug discovery through the isolation of natural products from Burkholderia.	Foxfire A, Buhrow AR, Orugunty RS, Smith L.	Expert Opin Drug Discov	10.1080/17460441.2021.1877655	2021
Metabolism	Efflux Pumps of Burkholderia thailandensis Control the Permeability Barrier of the Outer Membrane.	Krishnamoorthy G, Weeks JW, Zhang Z, Chandler CE, Xue H, Schweizer HP, Ernst RK, Zgurskaya HI.	Antimicrob Agents Chemother	10.1128/aac.00956-19	2019
Metabolism	Diversity of cultivated endophytic bacteria from sugarcane: genetic and biochemical characterization of Burkholderia cepacia complex isolates.	Mendes R, Pizzirani-Kleiner AA, Araujo WL, Raaijmakers JM.	Appl Environ Microbiol	10.1128/aem.01222-07	2007
Pathogenicity	Antisense phosphorodiamidate morpholino oligomers targeted to an essential gene inhibit Burkholderia cepacia complex.	Greenberg DE, Marshall-Batty KR, Brinster LR, Zarember KA, Shaw PA, Mellbye BL, Iversen PL, Holland SM, Geller BL.	J Infect Dis	10.1086/652807	2010
	Filtration and Normalization of Sequencing Read Data in Whole-Metagenome Shotgun Samples.	Chouvarine P, Wiehlmann L, Moran Losada P, DeLuca DS, Tummler B.	PLoS One	10.1371/journal.pone.0165015	2016
Metabolism	Terpene Synthase Genes Originated from Bacteria through Horizontal Gene Transfer Contribute to Terpenoid Diversity in Fungi.	Jia Q, Chen X, Kollner TG, Rinkel J, Fu J, Labbe J, Xiong W, Dickschat JS, Gershenzon J, Chen F.	Sci Rep	10.1038/s41598-019-45532-1	2019
Pathogenicity	Mouse beta-defensin-14, an antimicrobial ortholog of human beta-defensin-3.	Hinrichsen K, Podschun R, Schubert S, Schroder JM, Harder J, Proksch E.	Antimicrob Agents Chemother	10.1128/aac.01308-07	2008
	Rainbow Vectors for Broad-Range Bacterial Fluorescence Labeling.	Barbier M, Damron FH.	PLoS One	10.1371/journal.pone.0146827	2016
Enzymology	Identification and onion pathogenicity of Burkholderia cepacia complex isolates from the onion rhizosphere and onion field soil.	Jacobs JL, Fasi AC, Ramette A, Smith JJ, Hammerschmidt R, Sundin GW.	Appl Environ Microbiol	10.1128/aem.01941-07	2008
Pathogenicity	Burkholderia is highly resistant to human Beta-defensin 3.	Sahly H, Schubert S, Harder J, Rautenberg P, Ullmann U, Schroder J, Podschun R.	Antimicrob Agents Chemother	10.1128/aac.47.5.1739-1741.2003	2003
Metabolism	Biofilm-grown Burkholderia cepacia complex cells survive antibiotic treatment by avoiding production of reactive oxygen species.	Van Acker H, Sass A, Bazzini S, De Roy K, Udine C, Messiaen T, Riccardi G, Boon N, Nelis HJ, Mahenthiralingam E, Coenye T.	PLoS One	10.1371/journal.pone.0058943	2013
Phylogeny	Fluorescence in situ hybridization for rapid identification of Achromobacter xylosoxidans and Alcaligenes faecalis recovered from cystic fibrosis patients.	Wellinghausen N, Wirths B, Poppert S.	J Clin Microbiol	10.1128/jcm.00508-06	2006
	The organization of the quorum sensing luxI/R family genes in Burkholderia.	Choudhary KS, Hudaiberdiev S, Gelencser Z, Goncalves Coutinho B, Venturi V, Pongor S.	Int J Mol Sci	10.3390/ijms140713727	2013
	Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.	Phelps GA, Cheramie MN, Fernando DM, Selchow P, Meyer CJ, Waidyarachchi SL, Dharuman S, Liu J, Meuli M, Molin MD, Killam BY, Murphy PA, Reeve SM, Wilt LA, Anderson SM, Yang L, Lee RB, Temrikar ZH, Lukka PB, Meibohm B, Polikanov YS, Hobbie SN, Bottger EC, Sander P, Lee RE.	Proc Natl Acad Sci U S A	10.1073/pnas.2314101120	2024
	Enhanced susceptibility to pulmonary infection with Burkholderia cepacia in Cftr(-/-) mice.	Sajjan U, Thanassoulis G, Cherapanov V, Lu A, Sjolin C, Steer B, Wu YJ, Rotstein OD, Kent G, McKerlie C, Forstner J, Downey GP.	Infect Immun	10.1128/iai.69.8.5138-5150.2001	2001
Pathogenicity	The Impact of Efflux Pump Inhibitors on the Activity of Selected Non-Antibiotic Medicinal Products against Gram-Negative Bacteria.	Laudy AE, Kulinska E, Tyski S.	Molecules	10.3390/molecules22010114	2017
	Rapid identification of Acinetobacter spp. by fluorescence in situ hybridization (FISH) from colony and blood culture material.	Frickmann H, Essig A, Hagen RM, Riecker M, Jerke K, Ellison D, Poppert S.	Eur J Microbiol Immunol (Bp)	10.1556/eujmi.1.2011.4.4	2011
Pathogenicity	Genetic diversity and multihost pathogenicity of clinical and environmental strains of Burkholderia cenocepacia.	Springman AC, Jacobs JL, Somvanshi VS, Sundin GW, Mulks MH, Whittam TS, Viswanathan P, Gray RL, Lipuma JJ, Ciche TA.	Appl Environ Microbiol	10.1128/aem.00877-09	2009
	Synthesis and Antimicrobial Activity of Phosphonopeptide Derivatives Incorporating Single and Dual Inhibitors.	Ng KT, Perry JD, Marrs ECL, Orenga S, Anderson RJ, Gray M.	Molecules	10.3390/molecules25071557	2020
	Synthesis and antibacterial evaluation of macrocyclic diarylheptanoid derivatives.	Lin H, Bruhn DF, Maddox MM, Singh AP, Lee RE, Sun D.	Bioorg Med Chem Lett	10.1016/j.bmcl.2016.06.075	2016
Pathogenicity	Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin-Resistant Mycobacterium tuberculosis.	Mosaei H, Molodtsov V, Kepplinger B, Harbottle J, Moon CW, Jeeves RE, Ceccaroni L, Shin Y, Morton-Laing S, Marrs ECL, Wills C, Clegg W, Yuzenkova Y, Perry JD, Bacon J, Errington J, Allenby NEE, Hall MJ, Murakami KS, Zenkin N.	Mol Cell	10.1016/j.molcel.2018.08.028	2018
	Whole-genome assemblies of 56 burkholderia species.	Daligault HE, Davenport KW, Minogue TD, Bishop-Lilly KA, Broomall SM, Bruce DC, Chain PS, Coyne SR, Frey KG, Gibbons HS, Jaissle J, Koroleva GI, Ladner JT, Lo CC, Munk C, Palacios GF, Redden CL, Rosenzweig CN, Scholz MB, Johnson SL.	Genome Announc	10.1128/genomea.01106-14	2014
	Exploiting thiol-functionalized benzosiloxaboroles for achieving diverse substitution patterns - synthesis, characterization and biological evaluation of promising antibacterial agents.	Nowicki K, Krajewska J, Stepniewski TM, Wielechowska M, Winska P, Kaczmarczyk A, Korpowska J, Selent J, Marek-Urban PH, Durka K, Wozniak K, Laudy AE, Lulinski S.	RSC Med Chem	10.1039/d4md00061g	2024
	Aromatic Diboronic Acids as Effective KPC/AmpC Inhibitors.	Krajewska J, Chyzy P, Durka K, Winska P, Krzysko KA, Lulinski S, Laudy AE.	Molecules	10.3390/molecules28217362	2023
	Rapid identification of Stenotrophomonas maltophilia by peptide nucleic acid fluorescence in situ hybridization.	Hansen N, Rasmussen AK, Fiandaca MJ, Kragh KN, Bjarnsholt T, Hoiby N, Stender H, Guardabassi L.	New Microbes New Infect	10.1002/nmi2.38	2014
Phylogeny	DNA-Based diagnostic approaches for identification of Burkholderia cepacia complex, Burkholderia vietnamiensis, Burkholderia multivorans, Burkholderia stabilis, and Burkholderia cepacia genomovars I and III.	Mahenthiralingam E, Bischof J, Byrne SK, Radomski C, Davies JE, Av-Gay Y, Vandamme P.	J Clin Microbiol	10.1128/jcm.38.9.3165-3173.2000	2000
Enzymology	Pneumonia and septicemia caused by Burkholderia thailandensis in the United States.	Glass MB, Gee JE, Steigerwalt AG, Cavuoti D, Barton T, Hardy RD, Godoy D, Spratt BG, Clark TA, Wilkins PP.	J Clin Microbiol	10.1128/jcm.01585-06	2006
Metabolism	Burkholderia cenocepacia ET12 strain activates TNFR1 signalling in cystic fibrosis airway epithelial cells.	Sajjan US, Hershenson MB, Forstner JF, LiPuma JJ.	Cell Microbiol	10.1111/j.1462-5822.2007.01029.x	2008
Phylogeny	Molecular typing and exopolysaccharide biosynthesis of Burkholderia cepacia isolates from a Portuguese cystic fibrosis center.	Richau JA, Leitao JH, Correia M, Lito L, Salgado MJ, Barreto C, Cescutti P, Sa-Correia I.	J Clin Microbiol	10.1128/jcm.38.4.1651-1655.2000	2000
	Localization of Burkholderia cepacia complex bacteria in cystic fibrosis lungs and interactions with Pseudomonas aeruginosa in hypoxic mucus.	Schwab U, Abdullah LH, Perlmutt OS, Albert D, Davis CW, Arnold RR, Yankaskas JR, Gilligan P, Neubauer H, Randell SH, Boucher RC.	Infect Immun	10.1128/iai.01876-14	2014
Phylogeny	Direct PCR detection of Burkholderia cepacia complex and identification of its genomovars by using sputum as source of DNA.	Drevinek P, Hrbackova H, Cinek O, Bartosova J, Nyc O, Nemec A, Pohunek P.	J Clin Microbiol	10.1128/jcm.40.9.3485-3488.2002	2002
	Correlation between an in vitro invasion assay and a murine model of Burkholderia cepacia lung infection.	Cieri MV, Mayer-Hamblett N, Griffith A, Burns JL.	Infect Immun	10.1128/iai.70.3.1081-1086.2002	2002
Phylogeny	Development of a species-specific fur gene-based method for identification of the Burkholderia cepacia complex.	Lynch KH, Dennis JJ, Dennis JJ.	J Clin Microbiol	10.1128/jcm.01460-07	2008
	Distribution of quorum-sensing genes in the Burkholderia cepacia complex.	Lutter E, Lewenza S, Dennis JJ, Dennis JJ, Visser MB, Sokol PA.	Infect Immun	10.1128/iai.69.7.4661-4666.2001	2001
Phylogeny	Molecular method to assess the diversity of Burkholderia species in environmental samples.	Salles JF, De Souza FA, van Elsas JD.	Appl Environ Microbiol	10.1128/aem.68.4.1595-1603.2002	2002
Phylogeny	Biofilm formation and acyl homoserine lactone production in the Burkholderia cepacia complex.	Conway BA, Venu V, Speert DP.	J Bacteriol	10.1128/jb.184.20.5678-5685.2002	2002
Phylogeny	Correlation of wbiI genotype, serotype, and isolate source within species of the Burkholderia cepacia complex.	Vinion-Dubiel AD, Spilker T, Dean CR, Monteil H, LiPuma JJ, Goldberg JB.	J Clin Microbiol	10.1128/jcm.42.9.4121-4126.2004	2004
Pathogenicity	In Vitro and In Vivo Activities of DS86760016, a Novel Leucyl-tRNA Synthetase Inhibitor for Gram-Negative Pathogens.	Purnapatre KP, Rao M, Pandya M, Khanna A, Chaira T, Bambal R, Upadhyay DJ, Masuda N.	Antimicrob Agents Chemother	10.1128/aac.01987-17	2018
Enzymology	Distribution and expression of the ZmpA metalloprotease in the Burkholderia cepacia complex.	Gingues S, Kooi C, Visser MB, Subsin B, Sokol PA.	J Bacteriol	10.1128/jb.187.24.8247-8255.2005	2005
Phylogeny	Identification of members of the Burkholderia cepacia complex by species-specific PCR.	Whitby PW, Carter KB, Hatter KL, LiPuma JJ, Stull TL.	J Clin Microbiol	10.1128/jcm.38.8.2962-2965.2000	2000
Pathogenicity	Medical-grade honey enriched with antimicrobial peptides has enhanced activity against antibiotic-resistant pathogens.	Kwakman PH, de Boer L, Ruyter-Spira CP, Creemers-Molenaar T, Helsper JP, Vandenbroucke-Grauls CM, Zaat SA, te Velde AA.	Eur J Clin Microbiol Infect Dis	10.1007/s10096-010-1077-x	2011
	Genotypic analysis of Burkholderia cepacia isolates from 13 French cystic fibrosis centers.	Segonds C, Bingen E, Couetdic G, Mathy S, Brahimi N, Marty N, Plesiat P, Michel-Briand Y, Chabanon G.	J Clin Microbiol	10.1128/jcm.35.8.2055-2060.1997	1997
Metabolism	A novel eurythermic and thermostale lipase LipM from Pseudomonas moraviensis M9 and its application in the partial hydrolysis of algal oil.	Yang W, Cao H, Xu L, Zhang H, Yan Y.	BMC Biotechnol	10.1186/s12896-015-0214-0	2015
	Identification of RNase 8 as a novel human antimicrobial protein.	Rudolph B, Podschun R, Sahly H, Schubert S, Schroder JM, Harder J.	Antimicrob Agents Chemother	10.1128/aac.00246-06	2006
Metabolism	Susceptibility of Caenorhabditis elegans to Burkholderia infection depends on prior diet and secreted bacterial attractants.	Cooper VS, Carlson WA, Lipuma JJ.	PLoS One	10.1371/journal.pone.0007961	2009
Phylogeny	Distinguishing species of the Burkholderia cepacia complex and Burkholderia gladioli by automated ribotyping.	Brisse S, Verduin CM, Milatovic D, Fluit A, Verhoef J, Laevens S, Vandamme P, Tummler B, Verbrugh HA, van Belkum A.	J Clin Microbiol	10.1128/jcm.38.5.1876-1884.2000	2000
Pathogenicity	Small-molecule inhibition of choline catabolism in Pseudomonas aeruginosa and other aerobic choline-catabolizing bacteria.	Fitzsimmons LF, Flemer S, Wurthmann AS, Deker PB, Sarkar IN, Wargo MJ.	Appl Environ Microbiol	10.1128/aem.00504-11	2011
	Overcoming drug resistance with alginate oligosaccharides able to potentiate the action of selected antibiotics.	Khan S, Tondervik A, Sletta H, Klinkenberg G, Emanuel C, Onsoyen E, Myrvold R, Howe RA, Walsh TR, Hill KE, Thomas DW.	Antimicrob Agents Chemother	10.1128/aac.00525-12	2012
Metabolism	Cellular choline and glycine betaine pools impact osmoprotection and phospholipase C production in Pseudomonas aeruginosa.	Fitzsimmons LF, Hampel KJ, Wargo MJ.	J Bacteriol	10.1128/jb.00596-12	2012
Enzymology	Identification of Burkholderia spp. in the clinical microbiology laboratory: comparison of conventional and molecular methods.	van Pelt C, Verduin CM, Goessens WH, Vos MC, Tummler B, Segonds C, Reubsaet F, Verbrugh H, van Belkum A.	J Clin Microbiol	10.1128/jcm.37.7.2158-2164.1999	1999
Pathogenicity	Biocide susceptibility of the Burkholderia cepacia complex.	Rose H, Baldwin A, Dowson CG, Mahenthiralingam E.	J Antimicrob Chemother	10.1093/jac/dkn540	2009
	Epidemiology of Burkholderia cepacia infection in patients with cystic fibrosis: analysis by randomly amplified polymorphic DNA fingerprinting.	Mahenthiralingam E, Campbell ME, Henry DA, Speert DP.	J Clin Microbiol	10.1128/jcm.34.12.2914-2920.1996	1996
	Comparative analysis of plant and animal models for characterization of Burkholderia cepacia virulence.	Bernier SP, Silo-Suh L, Woods DE, Ohman DE, Sokol PA.	Infect Immun	10.1128/iai.71.9.5306-5313.2003	2003
	Oxazoline scaffold in synthesis of benzosiloxaboroles and related ring-expanded heterocycles: diverse reactivity, structural peculiarities and antimicrobial activity.	Krajewska J, Nowicki K, Durka K, Marek-Urban PH, Winska P, Stepniewski T, Wozniak K, Laudy AE, Lulinski S.	RSC Adv	10.1039/d2ra03910a	2022
	Vulnerability of pathogenic biofilms to Micavibrio aeruginosavorus.	Kadouri D, Venzon NC, O'Toole GA.	Appl Environ Microbiol	10.1128/aem.01893-06	2007
Metabolism	Role of quinolinate phosphoribosyl transferase in degradation of phthalate by Burkholderia cepacia DBO1.	Chang HK, Zylstra GJ.	J Bacteriol	10.1128/jb.181.10.3069-3075.1999	1999
Metabolism	Detection of heme-binding proteins in epidemic strains of Burkholderia cepacia.	Smalley JW, Charalabous P, Birss AJ, Hart CA.	Clin Diagn Lab Immunol	10.1128/cdli.8.3.509-514.2001	2001
Metabolism	Involvement of a plasmid-encoded type IV secretion system in the plant tissue watersoaking phenotype of Burkholderia cenocepacia.	Engledow AS, Medrano EG, Mahenthiralingam E, LiPuma JJ, Gonzalez CF.	J Bacteriol	10.1128/jb.186.18.6015-6024.2004	2004
Metabolism	Regulation of ornibactin biosynthesis and N-acyl-L-homoserine lactone production by CepR in Burkholderia cepacia.	Lewenza S, Sokol PA.	J Bacteriol	10.1128/jb.183.7.2212-2218.2001	2001
	Pharmacophore Modeling, Synthesis, and Antibacterial Evaluation of Chalcones and Derivatives.	Zhang M, Prior AM, Maddox MM, Shen WJ, Hevener KE, Bruhn DF, Lee RB, Singh AP, Reinicke J, Simmons CJ, Hurdle JG, Lee RE, Sun D.	ACS Omega	10.1021/acsomega.8b03174	2018
Metabolism	Siderophore production by cystic fibrosis isolates of Burkholderia cepacia.	Darling P, Chan M, Cox AD, Sokol PA.	Infect Immun	10.1128/iai.66.2.874-877.1998	1998
Pathogenicity	Identification of a novel virulence factor in Burkholderia cenocepacia H111 required for efficient slow killing of Caenorhabditis elegans.	Huber B, Feldmann F, Kothe M, Vandamme P, Wopperer J, Riedel K, Eberl L.	Infect Immun	10.1128/iai.72.12.7220-7230.2004	2004
	Soil bioremediation approaches for petroleum hydrocarbon polluted environments.	Koshlaf E, Ball AS.	AIMS Microbiol	10.3934/microbiol.2017.1.25	2017
Metabolism	Unusual interaction of a lipopolysaccharide isolated from Burkholderia cepacia with polymyxin B.	Shimomura H, Matsuura M, Saito S, Hirai Y, Isshiki Y, Kawahara K.	Infect Immun	10.1128/iai.71.9.5225-5230.2003	2003
	DISCRIMINATION OF Burkholderia mallei/pseudomallei FROM Burkholderia thailandensis BY SEQUENCE COMPARISON OF A FRAGMENT OF THE RIBOSOMAL PROTEIN S21 (RPSU) GENE.	Frickmann H, Chantratita N, Gauthier YP, Neubauer H, Hagen RM.	Eur J Microbiol Immunol (Bp)	10.1556/eujmi.2.2012.2.8	2012
	Construction and evaluation of plasmid vectors optimized for constitutive and regulated gene expression in Burkholderia cepacia complex isolates.	Lefebre MD, Valvano MA.	Appl Environ Microbiol	10.1128/aem.68.12.5956-5964.2002	2002
Metabolism	Sulfide production and oxidation by heterotrophic bacteria under aerobic conditions.	Xia Y, Lu C, Hou N, Xin Y, Liu J, Liu H, Xun L.	ISME J	10.1038/ismej.2017.125	2017
Pathogenicity	In Vitro Antibacterial Properties of Cefiderocol, a Novel Siderophore Cephalosporin, against Gram-Negative Bacteria.	Ito A, Sato T, Ota M, Takemura M, Nishikawa T, Toba S, Kohira N, Miyagawa S, Ishibashi N, Matsumoto S, Nakamura R, Tsuji M, Yamano Y.	Antimicrob Agents Chemother	10.1128/aac.01454-17	2018
Phylogeny	Identification and antimicrobial susceptibility of Alcaligenes xylosoxidans isolated from patients with cystic fibrosis.	Saiman L, Chen Y, Tabibi S, San Gabriel P, Zhou J, Liu Z, Lai L, Whittier S.	J Clin Microbiol	10.1128/jcm.39.11.3942-3945.2001	2001
	Development of structurally extended benzosiloxaboroles - synthesis and in vitro biological evaluation.	Pacholak P, Krajewska J, Winska P, Dunikowska J, Gogowska U, Mierzejewska J, Durka K, Wozniak K, Laudy AE, Lulinski S.	RSC Adv	10.1039/d1ra04127d	2021
Pathogenicity	The Influence of Efflux Pump Inhibitors on the Activity of Non-Antibiotic NSAIDS against Gram-Negative Rods.	Laudy AE, Mrowka A, Krajewska J, Tyski S.	PLoS One	10.1371/journal.pone.0147131	2016
Metabolism	Enhanced reliability and accuracy for field deployable bioforensic detection and discrimination of Xylella fastidiosa subsp. pauca, causal agent of citrus variegated chlorosis using razor ex technology and TaqMan quantitative PCR.	Ouyang P, Arif M, Fletcher J, Melcher U, Ochoa Corona FM.	PLoS One	10.1371/journal.pone.0081647	2013
Phylogeny	Rapid identification of Staphylococcus aureus directly from blood cultures by fluorescence in situ hybridization with peptide nucleic acid probes.	Oliveira K, Procop GW, Wilson D, Coull J, Stender H.	J Clin Microbiol	10.1128/jcm.40.1.247-251.2002	2002
	Interaction of ArmZ with the DNA-binding domain of MexZ induces expression of mexXY multidrug efflux pump genes and antimicrobial resistance in Pseudomonas aeruginosa.	Kawalek A, Modrzejewska M, Zieniuk B, Bartosik AA, Jagura-Burdzy G.	Antimicrob Agents Chemother	10.1128/aac.01199-19	2019
Metabolism	The type 2 secretion Pseudopilin, gspJ, is required for multihost pathogenicity of Burkholderia cenocepacia AU1054.	Somvanshi VS, Viswanathan P, Jacobs JL, Mulks MH, Sundin GW, Ciche TA.	Infect Immun	10.1128/iai.00558-10	2010
	Identification of genes regulated by the cepIR quorum-sensing system in Burkholderia cenocepacia by high-throughput screening of a random promoter library.	Subsin B, Chambers CE, Visser MB, Sokol PA.	J Bacteriol	10.1128/jb.01201-06	2007
Enzymology	Dual color fluorescence in situ hybridization (FISH) assays for detecting Mycobacterium tuberculosis and Mycobacterium avium complexes and related pathogens in cultures.	Shah J, Weltman H, Narciso P, Murphy C, Poruri A, Baliga S, Sharon L, York M, Cunningham G, Miller S, Caviedes L, Gilman R, Desmond E, Ramasamy R.	PLoS One	10.1371/journal.pone.0174989	2017
Enzymology	Species abundance and diversity of Burkholderia cepacia complex in the environment.	Ramette A, LiPuma JJ, Tiedje JM.	Appl Environ Microbiol	10.1128/aem.71.3.1193-1201.2005	2005
Pathogenicity	Treatment and prevention of Staphylococcus epidermidis experimental biomaterial-associated infection by bactericidal peptide 2.	Kwakman PH, te Velde AA, Vandenbroucke-Grauls CM, van Deventer SJ, Zaat SA.	Antimicrob Agents Chemother	10.1128/aac.00575-06	2006
	A locked nucleic acid (LNA)-based real-time PCR assay for the rapid detection of multiple bacterial antibiotic resistance genes directly from positive blood culture.	Zhu L, Shen D, Zhou Q, Li Z, Fang X, Li QZ.	PLoS One	10.1371/journal.pone.0120464	2015
Phylogeny	Fourier transform infrared spectroscopy for rapid identification of nonfermenting gram-negative bacteria isolated from sputum samples from cystic fibrosis patients.	Bosch A, Minan A, Vescina C, Degrossi J, Gatti B, Montanaro P, Messina M, Franco M, Vay C, Schmitt J, Naumann D, Yantorno O.	J Clin Microbiol	10.1128/jcm.02267-07	2008
Cultivation	Identification of Burkholderia cepacia isolates from patients with cystic fibrosis and use of a simple new selective medium.	Henry DA, Campbell ME, LiPuma JJ, Speert DP.	J Clin Microbiol	10.1128/jcm.35.3.614-619.1997	1997
Metabolism	Iron Acquisition Mechanisms and Their Role in the Virulence of Burkholderia Species.	Butt AT, Thomas MS.	Front Cell Infect Microbiol	10.3389/fcimb.2017.00460	2017
	Lipopolysaccharide of Burkholderia cepacia and its unique character to stimulate murine macrophages with relative lack of interleukin-1beta-inducing ability.	Shimomura H, Matsuura M, Saito S, Hirai Y, Isshiki Y, Kawahara K.	Infect Immun	10.1128/iai.69.6.3663-3669.2001	2001
Pathogenicity	Aminomethyl spectinomycins as therapeutics for drug-resistant respiratory tract and sexually transmitted bacterial infections.	Bruhn DF, Waidyarachchi SL, Madhura DB, Shcherbakov D, Zheng Z, Liu J, Abdelrahman YM, Singh AP, Duscha S, Rathi C, Lee RB, Belland RJ, Meibohm B, Rosch JW, Bottger EC, Lee RE.	Sci Transl Med	10.1126/scitranslmed.3010572	2015
	Priming of neutrophil respiratory burst activity by lipopolysaccharide from Burkholderia cepacia.	Hughes JE, Stewart J, Barclay GR, Govan JR.	Infect Immun	10.1128/iai.65.10.4281-4287.1997	1997
Metabolism	gfp-based N-acyl homoserine-lactone sensor systems for detection of bacterial communication.	Andersen JB, Heydorn A, Hentzer M, Eberl L, Geisenberger O, Christensen BB, Molin S, Givskov M.	Appl Environ Microbiol	10.1128/aem.67.2.575-585.2001	2001
Metabolism	Indole Biodegradation in Acinetobacter sp. Strain O153: Genetic and Biochemical Characterization.	Sadauskas M, Vaitekunas J, Gasparaviciute R, Meskys R.	Appl Environ Microbiol	10.1128/aem.01453-17	2017
Pathogenicity	A complete lipopolysaccharide inner core oligosaccharide is required for resistance of Burkholderia cenocepacia to antimicrobial peptides and bacterial survival in vivo.	Loutet SA, Flannagan RS, Kooi C, Sokol PA, Valvano MA.	J Bacteriol	10.1128/jb.188.6.2073-2080.2006	2006
Metabolism	Biosynthetic Genes for the Tetrodecamycin Antibiotics.	Gverzdys T, Nodwell JR.	J Bacteriol	10.1128/jb.00140-16	2016
Pathogenicity	Structure-guided discovery of novel aminoglycoside mimetics as antibacterial translation inhibitors.	Zhou Y, Gregor VE, Sun Z, Ayida BK, Winters GC, Murphy D, Simonsen KB, Vourloumis D, Fish S, Froelich JM, Wall D, Hermann T.	Antimicrob Agents Chemother	10.1128/aac.49.12.4942-4949.2005	2005
Metabolism	Pseudomonas aeruginosa alginate promotes Burkholderia cenocepacia persistence in cystic fibrosis transmembrane conductance regulator knockout mice.	Chattoraj SS, Murthy R, Ganesan S, Goldberg JB, Zhao Y, Hershenson MB, Sajjan US.	Infect Immun	10.1128/iai.01192-09	2010
Enzymology	Specific and rapid detection by fluorescent in situ hybridization of bacteria in clinical samples obtained from cystic fibrosis patients.	Hogardt M, Trebesius K, Geiger AM, Hornef M, Rosenecker J, Heesemann J.	J Clin Microbiol	10.1128/jcm.38.2.818-825.2000	2000
	Identification of IS1356, a new insertion sequence, and its association with IS402 in epidemic strains of Burkholderia cepacia infecting cystic fibrosis patients.	Tyler SD, Rozee KR, Johnson WM.	J Clin Microbiol	10.1128/jcm.34.7.1610-1616.1996	1996
Metabolism	A fusion promoter created by a new insertion sequence, IS1490, activates transcription of 2,4,5-trichlorophenoxyacetic acid catabolic genes in Burkholderia cepacia AC1100.	Hubner A, Hendrickson W.	J Bacteriol	10.1128/jb.179.8.2717-2723.1997	1997
	Cable pili and the 22-kilodalton adhesin are required for Burkholderia cenocepacia binding to and transmigration across the squamous epithelium.	Urban TA, Goldberg JB, Forstner JF, Sajjan US.	Infect Immun	10.1128/iai.73.9.5426-5437.2005	2005
Pathogenicity	Cold atmospheric air plasma sterilization against spores and other microorganisms of clinical interest.	Klampfl TG, Isbary G, Shimizu T, Li YF, Zimmermann JL, Stolz W, Schlegel J, Morfill GE, Schmidt HU.	Appl Environ Microbiol	10.1128/aem.00583-12	2012
Phylogeny	PCR-based detection and identification of Burkholderia cepacia complex pathogens in sputum from cystic fibrosis patients.	McDowell A, Mahenthiralingam E, Moore JE, Dunbar KE, Webb AK, Dodd ME, Martin SL, Millar BC, Scott CJ, Crowe M, Elborn JS.	J Clin Microbiol	10.1128/jcm.39.12.4247-4255.2001	2001
Pathogenicity	Covalent dimer species of beta-defensin Defr1 display potent antimicrobial activity against multidrug-resistant bacterial pathogens.	Taylor K, McCullough B, Clarke DJ, Langley RJ, Pechenick T, Hill A, Campopiano DJ, Barran PE, Dorin JR, Govan JR.	Antimicrob Agents Chemother	10.1128/aac.01531-06	2007
Enzymology	The alkane hydroxylase gene of Burkholderia cepacia RR10 is under catabolite repression control.	Marin MM, Smits TH, van Beilen JB, Rojo F.	J Bacteriol	10.1128/jb.183.14.4202-4209.2001	2001
Enzymology	Burkholderia cenocepacia ZmpB is a broad-specificity zinc metalloprotease involved in virulence.	Kooi C, Subsin B, Chen R, Pohorelic B, Sokol PA.	Infect Immun	10.1128/iai.00297-06	2006
Metabolism	Responses of well-differentiated airway epithelial cell cultures from healthy donors and patients with cystic fibrosis to Burkholderia cenocepacia infection.	Sajjan U, Keshavjee S, Forstner J.	Infect Immun	10.1128/iai.72.7.4188-4199.2004	2004
Pathogenicity	Biological properties of structurally related alpha-helical cationic antimicrobial peptides.	Scott MG, Yan H, Hancock RE.	Infect Immun	10.1128/iai.67.4.2005-2009.1999	1999
Metabolism	Genes for 2,4,5-trichlorophenoxyacetic acid metabolism in Burkholderia cepacia AC1100: characterization of the tftC and tftD genes and locations of the tft operons on multiple replicons.	Hubner A, Danganan CE, Xun L, Chakrabarty AM, Hendrickson W.	Appl Environ Microbiol	10.1128/aem.64.6.2086-2093.1998	1998
Enzymology	A novel alkaliphilic bacillus esterase belongs to the 13(th) bacterial lipolytic enzyme family.	Rao L, Xue Y, Zheng Y, Lu JR, Ma Y.	PLoS One	10.1371/journal.pone.0060645	2013
Metabolism	Chlamydomonas reinhardtii thermal tolerance enhancement mediated by a mutualistic interaction with vitamin B12-producing bacteria.	Xie B, Bishop S, Stessman D, Wright D, Spalding MH, Halverson LJ.	ISME J	10.1038/ismej.2013.43	2013
	Experimental adaptation of Burkholderia cenocepacia to onion medium reduces host range.	Ellis CN, Cooper VS.	Appl Environ Microbiol	10.1128/aem.01930-09	2010
Enzymology	Rapid detection, identification, and enumeration of Escherichia coli cells in municipal water by chemiluminescent in situ hybridization.	Stender H, Broomer AJ, Oliveira K, Perry-O'Keefe H, Hyldig-Nielsen JJ, Sage A, Coull J.	Appl Environ Microbiol	10.1128/aem.67.1.142-147.2001	2001
	Arbitrarily primed polymerase chain reaction as a rapid method to differentiate crossed from independent Pseudomonas cepacia infections in cystic fibrosis patients.	Bingen EH, Weber M, Derelle J, Brahimi N, Lambert-Zechovsky NY, Vidailhet M, Navarro J, Elion J.	J Clin Microbiol	10.1128/jcm.31.10.2589-2593.1993	1993
Metabolism	Burkholderia spp. alter Pseudomonas aeruginosa physiology through iron sequestration.	Weaver VB, Kolter R.	J Bacteriol	10.1128/jb.186.8.2376-2384.2004	2004
Pathogenicity	Conservation of the multidrug resistance efflux gene oprM in Pseudomonas aeruginosa.	Bianco N, Neshat S, Poole K.	Antimicrob Agents Chemother	10.1128/aac.41.4.853	1997
Enzymology	Multivariate analyses of Burkholderia species in soil: effect of crop and land use history.	Salles JF, van Veen JA, van Elsas JD.	Appl Environ Microbiol	10.1128/aem.70.7.4012-4020.2004	2004
	Identification of potential CepR regulated genes using a cep box motif-based search of the Burkholderia cenocepacia genome.	Chambers CE, Lutter EI, Visser MB, Law PP, Sokol PA.	BMC Microbiol	10.1186/1471-2180-6-104	2006
Phylogeny	Development of a PCR assay for identification of staphylococci at genus and species levels.	Martineau F, Picard FJ, Ke D, Paradis S, Roy PH, Ouellette M, Bergeron MG.	J Clin Microbiol	10.1128/jcm.39.7.2541-2547.2001	2001
Phylogeny	Staph ID/R: a rapid method for determining staphylococcus species identity and detecting the mecA gene directly from positive blood culture.	Pasko C, Hicke B, Dunn J, Jaeckel H, Nieuwlandt D, Weed D, Woodruff E, Zheng X, Jenison R.	J Clin Microbiol	10.1128/jcm.05534-11	2012
	Role of ornibactin biosynthesis in the virulence of Burkholderia cepacia: characterization of pvdA, the gene encoding L-ornithine N(5)-oxygenase.	Sokol PA, Darling P, Woods DE, Mahenthiralingam E, Kooi C.	Infect Immun	10.1128/iai.67.9.4443-4455.1999	1999
Metabolism	Sensitive detection of a novel class of toluene-degrading denitrifiers, Azoarcus tolulyticus, with small-subunit rRNA primers and probes.	Zhou J, Palumbo AV, Tiedje JM.	Appl Environ Microbiol	10.1128/aem.63.6.2384-2390.1997	1997
	Characterization of genes involved in biosynthesis of a novel antibiotic from Burkholderia cepacia BC11 and their role in biological control of Rhizoctonia solani.	Kang Y, Carlson R, Tharpe W, Schell MA.	Appl Environ Microbiol	10.1128/aem.64.10.3939-3947.1998	1998
Phylogeny	Detection and characterization of human Ureaplasma species and serovars by real-time PCR.	Xiao L, Glass JI, Paralanov V, Yooseph S, Cassell GH, Duffy LB, Waites KB.	J Clin Microbiol	10.1128/jcm.01877-09	2010
	Conditions for natural transformation of Ralstonia solanacearum.	Bertolla F, Van Gijsegem F, Nesme X, Simonet P.	Appl Environ Microbiol	10.1128/aem.63.12.4965-4968.1997	1997
	Psychrotolerant bacteria isolated from arctic soil that degrade polychlorinated biphenyls at low temperatures	Master ER, Mohn WW.	Appl Environ Microbiol	10.1128/aem.64.12.4823-4829.1998	1998
Enzymology	Use of tuf sequences for genus-specific PCR detection and phylogenetic analysis of 28 streptococcal species.	Picard FJ, Ke D, Boudreau DK, Boissinot M, Huletsky A, Richard D, Ouellette M, Roy PH, Bergeron MG.	J Clin Microbiol	10.1128/jcm.42.8.3686-3695.2004	2004
	Activities of LL-37, a cathelin-associated antimicrobial peptide of human neutrophils.	Turner J, Cho Y, Dinh NN, Waring AJ, Lehrer RI.	Antimicrob Agents Chemother	10.1128/aac.42.9.2206	1998
	Enzyme-linked immunofiltration assay To estimate attachment of thiobacilli to pyrite	Dziurla MA, Achouak W, Lam BT, Heulin T, Berthelin J.	Appl Environ Microbiol	10.1128/aem.64.8.2937-2942.1998	1998
Enzymology	Rapid concentration and molecular enrichment approach for sensitive detection of Escherichia coli and Shigella species in potable water samples.	Maheux AF, Bissonnette L, Boissinot M, Bernier JL, Huppe V, Picard FJ, Berube E, Bergeron MG.	Appl Environ Microbiol	10.1128/aem.02337-10	2011
Metabolism	Functional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1.	Mavrodi DV, Bonsall RF, Delaney SM, Soule MJ, Phillips G, Thomashow LS.	J Bacteriol	10.1128/jb.183.21.6454-6465.2001	2001
Metabolism	Diversity and evolution of the phenazine biosynthesis pathway.	Mavrodi DV, Peever TL, Mavrodi OV, Parejko JA, Raaijmakers JM, Lemanceau P, Mazurier S, Heide L, Blankenfeldt W, Weller DM, Thomashow LS.	Appl Environ Microbiol	10.1128/aem.02009-09	2010
Pathogenicity	New real-time PCR assay for rapid detection of methicillin-resistant Staphylococcus aureus directly from specimens containing a mixture of staphylococci.	Huletsky A, Giroux R, Rossbach V, Gagnon M, Vaillancourt M, Bernier M, Gagnon F, Truchon K, Bastien M, Picard FJ, van Belkum A, Ouellette M, Roy PH, Bergeron MG.	J Clin Microbiol	10.1128/jcm.42.5.1875-1884.2004	2004
Pathogenicity	Discovery of a novel class of boron-based antibacterials with activity against gram-negative bacteria.	Hernandez V, Crepin T, Palencia A, Cusack S, Akama T, Baker SJ, Bu W, Feng L, Freund YR, Liu L, Meewan M, Mohan M, Mao W, Rock FL, Sexton H, Sheoran A, Zhang Y, Zhang YK, Zhou Y, Nieman JA, Anugula MR, Keramane el M, Savariraj K, Reddy DS, Sharma R, Subedi R, Singh R, O'Leary A, Simon NL, De Marsh PL, Mushtaq S, Warner M, Livermore DM, Alley MR, Plattner JJ.	Antimicrob Agents Chemother	10.1128/aac.02058-12	2013
	Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia.	Govan JR, Deretic V.	Microbiol Rev	10.1128/mr.60.3.539-574.1996	1996
	Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.	O'Grady EP, Viteri DF, Malott RJ, Sokol PA.	BMC Genomics	10.1186/1471-2164-10-441	2009
	A highly selective PCR protocol for detecting 16S rRNA genes of the genus Pseudomonas (sensu stricto) in environmental samples.	Widmer F, Seidler RJ, Gillevet PM, Watrud LS, Di Giovanni GD.	Appl Environ Microbiol	10.1128/aem.64.7.2545-2553.1998	1998
	Antimicrobial peptides and proteins of the horse--insights into a well-armed organism.	Bruhn O, Grotzinger J, Cascorbi I, Jung S.	Vet Res	10.1186/1297-9716-42-98	2011
	Linkage analysis of geographic and clinical clusters in Pseudomonas cepacia infections by multilocus enzyme electrophoresis and ribotyping.	Johnson WM, Tyler SD, Rozee KR.	J Clin Microbiol	10.1128/jcm.32.4.924-930.1994	1994
	Chromogenic hydroxyanthraquinone-based enzyme substrates for the detection of microbial beta-d-galactosidase, beta-d-glucuronidase and beta-d-ribosidase.	Burton M, Garcha A, Marrs ECL, Perry JD, Stanforth SP, Turnbull G, Turner HJ.	RSC Adv	10.1039/d4ra06418f	2025
Cultivation	Evaluation of Three Culture Media for Isolation of Burkholderia cepacia Complex from Respiratory Samples of Patients with Cystic Fibrosis.	Marrs ECL, Perry A, Perry JD.	Microorganisms	10.3390/microorganisms9122604	2021
Metabolism	The Synthesis of L-Alanyl and beta-Alanyl Derivatives of 2-Aminoacridone and Their Application in the Detection of Clinically-Important Microorganisms.	Cellier M, James AL, Orenga S, Perry JD, Turnbull G, Stanforth SP.	PLoS One	10.1371/journal.pone.0158378	2016
	Evaluation of a Rapid Diagnostic Test for Detection of Burkholderia pseudomallei in the Lao People's Democratic Republic.	Woods KL, Boutthasavong L, NicFhogartaigh C, Lee SJ, Davong V, AuCoin DP, Dance DAB.	J Clin Microbiol	10.1128/jcm.02002-17	2018
Enzymology	Evaluation of a simple blood culture amplification and antigen detection method for diagnosis of Salmonella enterica serovar typhi bacteremia.	Castonguay-Vanier J, Davong V, Bouthasavong L, Sengdetka D, Simmalavong M, Seupsavith A, Dance DA, Baker S, Le Thi Phuong T, Vongsouvath M, Newton PN.	J Clin Microbiol	10.1128/jcm.02360-12	2013
Enzymology	Evaluation of Molecular Methods To Improve the Detection of Burkholderia pseudomallei in Soil and Water Samples from Laos.	Knappik M, Dance DA, Rattanavong S, Pierret A, Ribolzi O, Davong V, Silisouk J, Vongsouvath M, Newton PN, Dittrich S.	Appl Environ Microbiol	10.1128/aem.04204-14	2015
Enzymology	Novel selective medium for isolation of Burkholderia pseudomallei.	Howard K, Inglis TJ.	J Clin Microbiol	10.1128/jcm.41.7.3312-3316.2003	2003
	Diagnosing Fungal Keratitis and Simultaneously Identifying Fusarium and Aspergillus Keratitis with a Dot Hybridization Array.	Kuo MT, Hsu SL, You HL, Kuo SF, Fang PC, Yu HJ, Chen A, Tseng CY, Lai YH, Chen JL.	J Fungi (Basel)	10.3390/jof8010064	2022
Enzymology	Acanthamoeba-Campylobacter coculture as a novel method for enrichment of Campylobacter species.	Axelsson-Olsson D, Ellstrom P, Waldenstrom J, Haemig PD, Brudin L, Olsen B.	Appl Environ Microbiol	10.1128/aem.01305-07	2007
	Development of multiplex cross displacement amplification combined with lateral flow biosensor assay for detection of virulent shigella sonnei.	Wang Y, He Z, Ablimit P, Ji S, Jin D.	Front Cell Infect Microbiol	10.3389/fcimb.2022.1012105	2022
Metabolism	In vivo fluorescence imaging of bacteriogenic cyanide in the lungs of live mice infected with cystic fibrosis pathogens.	Nam SW, Chen X, Lim J, Kim SH, Kim ST, Cho YH, Yoon J, Park S.	PLoS One	10.1371/journal.pone.0021387	2011
	In vitro susceptibility of Burkholderia cepacia to ceftazidime-avibactam: A systematic review.	Zomorodi AR, Ghanbari Afra L, Faridafshar H, Faraji SN, Zarepour F, Mavaei M, Rahmanian M.	New Microbes New Infect	10.1016/j.nmni.2025.101601	2025
	Single and dual RPA-CRISPR/Cas assays for point-of-need detection of Stewart's wilt pathogen (Pantoea stewartii subsp. stewartii) of corn and Maize dwarf mosaic virus.	Tian Q, Zhou H, Zhao Z, Zhang Y, Zhao W, Cai L, Guo T.	Pest Manag Sci	10.1002/ps.8597	2025
	Screening of bacterial endophytes of larch against Neofusicoccum laricinum and validation of their safety.	Liu Y, Han S, Song L, Li L, Wang H, Pan M, Tan J.	Microbiol Spectr	10.1128/spectrum.04112-23	2024
	Evaluation of Burkholderia cepacia Complex Bacteria Pathogenicity Using Caenorhabditis elegans.	Tedesco P, Di Schiavi E, Esposito FP, de Pascale D.	Bio Protoc	10.21769/bioprotoc.1964	2016
	Potential PGPR Properties of Cellulolytic, Nitrogen-Fixing, Phosphate-Solubilizing Bacteria in Rehabilitated Tropical Forest Soil.	Tang A, Haruna AO, Majid NMA, Jalloh MB.	Microorganisms	10.3390/microorganisms8030442	2020
Pathogenicity	Transport of nanoparticles and tobramycin-loaded liposomes in Burkholderia cepacia complex biofilms.	Messiaen AS, Forier K, Nelis H, Braeckmans K, Coenye T.	PLoS One	10.1371/journal.pone.0079220	2013
	Effect of beta-Lactamase inhibitors on in vitro activity of beta-Lactam antibiotics against Burkholderia cepacia complex species.	Everaert A, Coenye T.	Antimicrob Resist Infect Control	10.1186/s13756-016-0142-3	2016
	Detection of beta-alanyl aminopeptidase as a biomarker for Pseudomonas aeruginosa in the sputum of patients with cystic fibrosis using exogenous volatile organic compound evolution.	Thompson R, Stephenson D, Sykes HE, Perry JD, Stanforth SP, Dean JR.	RSC Adv	10.1039/c9ra08386c	2020
	New Antimicrobial Strategies to Treat Multi-Drug Resistant Infections Caused by Gram-Negatives in Cystic Fibrosis.	Scoffone VC, Barbieri G, Irudal S, Trespidi G, Buroni S.	Antibiotics (Basel)	10.3390/antibiotics13010071	2024
Metabolism	The Role of Reactive Oxygen Species in Antibiotic-Induced Cell Death in Burkholderia cepacia Complex Bacteria.	Van Acker H, Gielis J, Acke M, Cools F, Cos P, Coenye T.	PLoS One	10.1371/journal.pone.0159837	2016
Pathogenicity	Investigating the Role of the Host Multidrug Resistance Associated Protein Transporter Family in Burkholderia cepacia Complex Pathogenicity Using a Caenorhabditis elegans Infection Model.	Tedesco P, Visone M, Parrilli E, Tutino ML, Perrin E, Maida I, Fani R, Ballestriero F, Santos R, Pinilla C, Di Schiavi E, Tegos G, de Pascale D.	PLoS One	10.1371/journal.pone.0142883	2015
	Exploring the Anti-Burkholderia cepacia Complex Activity of Essential Oils: A Preliminary Analysis.	Maida I, Lo Nostro A, Pesavento G, Barnabei M, Calonico C, Perrin E, Chiellini C, Fondi M, Mengoni A, Maggini V, Vannacci A, Gallo E, Bilia AR, Flamini G, Gori L, Firenzuoli F, Fani R.	Evid Based Complement Alternat Med	10.1155/2014/573518	2014
	Antimicrobial Activity of Monoramnholipids Produced by Bacterial Strains Isolated from the Ross Sea (Antarctica).	Tedesco P, Maida I, Palma Esposito F, Tortorella E, Subko K, Ezeofor CC, Zhang Y, Tabudravu J, Jaspars M, Fani R, de Pascale D.	Mar Drugs	10.3390/md14050083	2016
	1-Aminocyclopropane-1-carboxylate deaminase producers associated to maize and other Poaceae species.	Bouffaud ML, Renoud S, Dubost A, Moenne-Loccoz Y, Muller D.	Microbiome	10.1186/s40168-018-0503-7	2018
Pathogenicity	Antibacterial activity of a lectin-like Burkholderia cenocepacia protein.	Ghequire MG, De Canck E, Wattiau P, Van Winge I, Loris R, Coenye T, De Mot R.	Microbiologyopen	10.1002/mbo3.95	2013
Phylogeny	Novel pan-genomic analysis approach in target selection for multiplex PCR identification and detection of Burkholderia pseudomallei, Burkholderia thailandensis, and Burkholderia cepacia complex species: a proof-of-concept study.	Ho CC, Lau CC, Martelli P, Chan SY, Tse CW, Wu AK, Yuen KY, Lau SK, Woo PC.	J Clin Microbiol	10.1128/jcm.01702-10	2011
	Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability.	Menard A, de Los Santos PE, Graindorge A, Cournoyer B.	BMC Genomics	10.1186/1471-2164-8-308	2007
	Burkholderia cepacia complex bacteria from clinical and environmental sources in Italy: genomovar status and distribution of traits related to virulence and transmissibility.	Bevivino A, Dalmastri C, Tabacchioni S, Chiarini L, Belli ML, Piana S, Materazzo A, Vandamme P, Manno G.	J Clin Microbiol	10.1128/jcm.40.3.846-851.2002	2002
Genetics	Multilocus sequence typing breathes life into a microbial metagenome.	Mahenthiralingam E, Baldwin A, Drevinek P, Vanlaere E, Vandamme P, LiPuma JJ, Dowson CG.	PLoS One	10.1371/journal.pone.0000017	2006
Enzymology	Low rates of Pseudomonas aeruginosa misidentification in isolates from cystic fibrosis patients.	Kidd TJ, Ramsay KA, Hu H, Bye PT, Elkins MR, Grimwood K, Harbour C, Marks GB, Nissen MD, Robinson PJ, Rose BR, Sloots TP, Wainwright CE, Bell SC, ACPinCF Investigators.	J Clin Microbiol	10.1128/jcm.00014-09	2009
Phylogeny	Development of a recA gene-based identification approach for the entire Burkholderia genus.	Payne GW, Vandamme P, Morgan SH, Lipuma JJ, Coenye T, Weightman AJ, Jones TH, Mahenthiralingam E.	Appl Environ Microbiol	10.1128/aem.71.7.3917-3927.2005	2005
	Novel Conopeptides of Largely Unexplored Indo Pacific Conus sp.	Lebbe EK, Ghequire MG, Peigneur S, Mille BG, Devi P, Ravichandran S, Waelkens E, D'Souza L, De Mot R, Tytgat J.	Mar Drugs	10.3390/md14110199	2016
	Burkholderia thailandensis E125 harbors a temperate bacteriophage specific for Burkholderia mallei.	Woods DE, Jeddeloh JA, Fritz DL, DeShazer D.	J Bacteriol	10.1128/jb.184.14.4003-4017.2002	2002
Metabolism	The antimicrobial compound xantholysin defines a new group of Pseudomonas cyclic lipopeptides.	Li W, Rokni-Zadeh H, De Vleeschouwer M, Ghequire MG, Sinnaeve D, Xie GL, Rozenski J, Madder A, Martins JC, De Mot R.	PLoS One	10.1371/journal.pone.0062946	2013
Phylogeny	Genomic diversity of Burkholderia pseudomallei clinical isolates: subtractive hybridization reveals a Burkholderia mallei-specific prophage in B. pseudomallei 1026b.	DeShazer D.	J Bacteriol	10.1128/jb.186.12.3938-3950.2004	2004
Pathogenicity	Outer membrane vesicles produced by Burkholderia cepacia cultured with subinhibitory concentrations of ceftazidime enhance pro-inflammatory responses.	Kim SY, Kim MH, Son JH, Kim SI, Yun SH, Kim K, Kim S, Shin M, Lee JC	Virulence	10.1080/21505594.2020.1802193	2020
Enzymology	Enantioselective synthesis of a chiral intermediate of himbacine analogs by Burkholderia cepacia lipase A.	Chen Y, Gao F, Zheng G, Gao S	Biotechnol Lett	10.1007/s10529-020-02969-z	2020
	Antibacterial effects of microbial synthesized silver-copper nanoalloys on Escherichia coli, Burkholderia cepacia, Listeria monocytogenes and Brucella abortus.	Mohammadi S, Jazani NH, Kouhkan M, Babaganjeh LA	Iran J Microbiol		2018
Metabolism	Application of lipase from Burkholderia cepacia in the degradation of agro-industrial effluent.	Mello Bueno PR, de Oliveira TF, Castiglioni GL, Soares Junior MS, Ulhoa CJ	Water Sci Technol	10.2166/wst.2015.037	2015
	First Report of Bacterial Leaf Streak of Strelitzia reginae Caused by Burkholderia cepacia.	You CP, Xiang MM, Zhang YX	Plant Dis	10.1094/PDIS-02-13-0205-PDN	2014
Cultivation	Influence of Legionella pneumophila and other water bacteria on the survival and growth of Acanthamoeba polyphaga.	Anacarso I, Guerrieri E, Bondi M, de Niederhausern S, Iseppi R, Sabia C, Contri M, Borella P, Messi P	Arch Microbiol	10.1007/s00203-010-0618-0	2010
Enzymology	Isolation, heterologous expression and characterization of an endo-polygalacturonase produced by the phytopathogen Burkholderia cepacia.	Massa C, Degrassi G, Devescovi G, Venturi V, Lamba D	Protein Expr Purif	10.1016/j.pep.2007.03.019	2007
Pathogenicity	Identification of an RTX determinant of Burkholderia cenocepacia J2315 by subtractive hybridization.	Whitby PW, VanWagoner TM, Taylor AA, Seale TW, Morton DJ, LiPuma JJ, Stull TL	J Med Microbiol	10.1099/jmm.0.46138-0	2006
Metabolism	Identification of quorum-sensing-regulated genes of Burkholderia cepacia.	Aguilar C, Friscina A, Devescovi G, Kojic M, Venturi V	J Bacteriol	10.1128/JB.185.21.6456-6462.2003	2003
Metabolism	Transmissible Burkholderia cepacia genomovar IIIa strains bind and convert monomeric iron(III) protoporphyrin IX into the mu-oxo oligomeric form.	Smalley JW, Charalabous P, Hart CA, Silver J	Microbiology (Reading)	10.1099/mic.0.26160-0	2003
Metabolism	Quorum-sensing system and stationary-phase sigma factor (rpoS) of the onion pathogen Burkholderia cepacia genomovar I type strain, ATCC 25416.	Aguilar C, Bertani I, Venturi V	Appl Environ Microbiol	10.1128/AEM.69.3.1739-1747.2003	2003
Enzymology	Construction of a deep-rough mutant of Burkholderia cepacia ATCC 25416 and characterization of its chemical and biological properties.	Gronow S, Noah C, Blumenthal A, Lindner B, Brade H	J Biol Chem	10.1074/jbc.M206942200	2002
Metabolism	Role of cytosine deaminase and beta-alanine-pyruvate transaminase in pyrimidine base catabolism by Burkholderia cepacia.	West TP	Antonie Van Leeuwenhoek	10.1023/a:1002062202282	2000
Phylogeny	Development of rRNA-based PCR assays for identification of Burkholderia cepacia complex isolates recovered from cystic fibrosis patients.	LiPuma JJ, Dulaney BJ, McMenamin JD, Whitby PW, Stull TL, Coenye T, Vandamme P	J Clin Microbiol	10.1128/JCM.37.10.3167-3170.1999	1999
Phylogeny	Isolation and characterisation of disodium (4-amino-4-deoxy-beta-L- arabinopyranosyl)-(1-->8)-(D-glycero-alpha-D-talo-oct-2-ulopyranosylona te)- (2-->4)-(methyl 3-deoxy-D-manno-oct-2-ulopyranosid)onate from the lipopolysaccharide of Burkholderia cepacia.	Isshiki Y, Kawahara K, Zahringer U	Carbohydr Res	10.1016/s0008-6215(98)00179-7	1998
Enzymology	Mobilization, cloning, and sequence determination of a plasmid-encoded polygalacturonase from a phytopathogenic Burkholderia (Pseudomonas) cepacia.	Gonzalez CF, Pettit EA, Valadez VA, Provin EM	Mol Plant Microbe Interact	10.1094/MPMI.1997.10.7.840	1997
Enzymology	Cloning and expression of the major porin protein gene opcP of Burkholderia (formerly Pseudomonas) cepacia in Escherichia coli.	Tsujimoto H, Gotoh N, Yamagishi J, Oyamada Y, Nishino T	Gene	10.1016/s0378-1119(96)00692-0	1997
Phylogeny	Systematic study of the genus Vogesella gen. nov. and its type species, Vogesella indigofera comb. nov.	Grimes DJ, Woese CR, MacDonell MT, Colwell RR	Int J Syst Bacteriol	10.1099/00207713-47-1-19	1997
Metabolism	Pyrimidine synthesis in Burkholderia cepacia ATCC 25416.	Li K, West TP	Lett Appl Microbiol	10.1111/j.1472-765x.1995.tb01075.x	1995
Metabolism	Isolation of uracil auxotrophs from Burkholderia cepacia ATCC 25416.	Li K, West TP	Lett Appl Microbiol	10.1111/j.1472-765x.1995.tb01074.x	1995
Metabolism	Ornibactin production and transport properties in strains of Burkholderia vietnamiensis and Burkholderia cepacia (formerly Pseudomonas cepacia).	Meyer JM, Van VT, Stintzi A, Berge O, Winkelmann G	Biometals	10.1007/BF00141604	1995
Enzymology	A physical genome map of the Burkholderia cepacia type strain.	Rodley PD, Romling U, Tummler B	Mol Microbiol	10.1111/j.1365-2958.1995.mmi_17010057.x	1995
Metabolism	Cepabactin from Pseudomonas cepacia, a new type of siderophore.	Meyer JM, Hohnadel D, Halle F	J Gen Microbiol	10.1099/00221287-135-6-1479	1989
Metabolism	Occurrence of succinyl derivatives in the catabolism of arginine in Pseudomonas cepacia.	Vander Wauven C, Stalon V	J Bacteriol	10.1128/jb.164.2.882-886.1985	1985
Phenotype	[Phenotype characteristics of 100 strains of Pseudomonas cepacia. Proposition of a biovars classification (author's transl)].	Richard C, Monteil H, Megraud F, Chatelain R, Laurent B	Ann Biol Clin (Paris)		1981
Phylogeny	Bordetella holmesii sp. nov., a new gram-negative species associated with septicemia.	Weyant RS, Hollis DG, Weaver RE, Amin MF, Steigerwalt AG, O'Connor SP, Whitney AM, Daneshvar MI, Moss CW, Brenner DJ.	J Clin Microbiol	10.1128/jcm.33.1.1-7.1995	1995

References

#3094	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 7288
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#37582	; Curators of the CIP;
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68369	Automatically annotated from API 20NE .
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#117247	Collection of Institut Pasteur ; Curators of the CIP; CIP 80.24
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Burkholderia cepacia (DSM 7288, ATCC 25416, DSM 9897)

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