Actinobacillus suis (DSM 19774, ATCC 15557, JCM 2433)

Name: Actinobacillus suis (DSM 19774, ATCC 15557, JCM 2433)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 11681

Type strain

Strain Designation 1208

Culture col. no. DSM 19774 ATCC 15557 JCM 2433 1208 GTC 00492

NCBI tax ID(s) 716

Special Collections DSMZ JCM

History DSMZ <- JCM <- R. Sakazaki <- ATCC <- A. D. Alexander; 1208 (Actinobacillus lignieresii) <- H. Baker and J. Evans JCM <-- R. Sakazaki <-- ATCC 15557 <-- A. D. Alexander 1208 (Actinobacillus lignieresii) <-- H. Baker and J. Evans.

Links

Actinobacillus suis 1208 is a human pathogen that was isolated from blood of swine.

human pathogen genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 105400

ATCC 15557,JCM 2433,DSM 19774

@ref 20215

Last LPSN update 2026-05-29 08:27:37

Domain Bacteria

Phylum Pseudomonadota

Class Gammaproteobacteria

Order Pasteurellales

Family Pasteurellaceae

Genus Actinobacillus

Species Actinobacillus suis

Full scientific name Actinobacillus suis van Dorssen and Jaartsveld 1962 (Approved Lists 1980)

BacDive ID	Other strains from **Actinobacillus suis** (10)	Type strain
11682	A. suis 1276/61, DSM 22433, ATCC 33415, CCM 5586, ... (type strain)
134801	A. suis 24576, CIP 66.28
135663	A. suis 443, CIP 69.36
137502	A. suis 443, CIP 67.9
139148	A. suis CIP 101371
139346	A. suis PG97-2(2), 9642367, CIP 105099
144139	A. suis CCUG 23136
144397	A. suis CCUG 24856, MCCM 00183
152808	A. suis CCUG 47662
152809	A. suis CCUG 47663

Morphology

Cell morphology

@ref	Gram stain	Confidence
125438	negative	97

Culture and growth conditions

Culture medium

@ref	Name	Growth	Medium link	Composition
8309	BHI MEDIUM (DSMZ Medium 215)		Medium recipe at MediaDive	Name: BHI MEDIUM (DSMZ Medium 215) Composition: Brain heart infusion 37.0 g/l Distilled water

Culture temp

@ref	Growth	Type	Temperature (°C)
8309	positive	growth	37
67770	positive	growth	37

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
125439	obligate aerobe	97.039

Spore formation

@ref	Spore formation	Confidence
125439		98.761

Compound production

67770

CompoundHemolysin

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68377	15824 ChEBI	D-fructose	+	builds acid from	from API NH
68377	17634 ChEBI	D-glucose	+	builds acid from	from API NH
68377	17306 ChEBI	maltose	+	builds acid from	from API NH
68377	27897 ChEBI	tryptophan	-	energy source	from API NH
68377	16199 ChEBI	urea	+	hydrolysis	from API NH

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68377	35581 ChEBI	indole		from API NH

Metabolite tests

@ref	Chebi-ID	Metabolite	Indole test
68377	35581 ChEBI	indole	-	from API NH

Enzymes

@ref	Value	Activity	Ec
68377	alkaline phosphatase	+	3.1.3.1	from API NH
68377	gamma-glutamyltransferase	-	2.3.2.2	from API NH
68377	lipase	+		from API NH
68377	proline-arylamidase	-	3.4.11.5	from API NH
68377	tryptophan deaminase	-	4.1.99.1	from API NH
68377	urease	+	3.5.1.5	from API NH

API NH

@ref	PEN	GLU	FRU	MAL	SAC	ODC	URE	LIP	PAL	beta GAL	ProA	GGT	IND
8309	+	+	+	+	-	+	+	+	+	-	-	-	-
8309	-	+	+	+	+	-	+	+	+	+	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Host	#Mammals	#Suidae (Pig,Swine)
#Host Body Product	#Fluids	#Blood

Isolation

@ref	Sample type	Country	Country ISO 3 Code	Continent
8309	blood of swine	USA	USA	North America
67770	Blood of adult swine killed by atomic blast

Taxonmaps

69479

Global distribution of 16S sequence LC383928 (>99% sequence identity) for Actinobacillus suis from Microbeatlas

Aquatic Samples	45
Soil Samples	7
Animal Samples	1302
Plant Samples	2
Total Samples	1356

Interaction and safety

Risk assessment

@ref	Pathogenicity human	Pathogenicity animal	Biosafety level	Biosafety level comment
8309			2	Risk group (German classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	NCBI tax ID	Score
67770	ASM208168v1 assembly for Actinobacillus suis ATCC 15557	contig	GCA_002081685	716.11	716	63.06

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Actinobacillus suis strain ATCC 15557 16S ribosomal RNA gene, partial sequence	M75071	1478	716
8309	Actinobacillus suis 16S ribosomal RNA gene, partial sequence	AF015299	1341	743972
67770	Actinobacillus suis JCM 2433 gene for 16S ribosomal RNA, partial sequence	LC383928	1462	716

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: ASM208168v1 assembly for Actinobacillus suis ATCC 15557
NCBI: GCA_002081685

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	97.04	no
125439	gram_stain	BacteriaNetⓘ	negative	46.64	no
125439	motility	BacteriaNetⓘ	no	72.59	no
125439	spore_formation	BacteriaNetⓘ	no	98.76	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Actinobacillus suis strain ATCC 15557
PATRIC: 716.11

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	97.00	no
125438	anaerobic	anaerobicⓘ	no	92.29	no
125438	spore-forming	spore-formingⓘ	no	88.61	no
125438	aerobic	aerobicⓘ	no	73.53	no
125438	thermophilic	thermophileⓘ	no	98.00	yes
125438	flagellated	motile2+ⓘ	no	89.32	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Actinobacillus suis isolated from diseased pigs are phylogenetically related but harbour different number of toxin gene copies in their genomes.	Kulathunga DGRS, Fakher AA, Costa MO.	Vet Rec Open	10.1002/vro2.45	2022
Phylogeny	In silico-derived Actinobacillus equuli-specific DNA markers and development of associated PCR assays.	Songsungthong W, Pornthanakasem W, Leartsakulpanich U, Srijuntongsiri G.	J Vet Diagn Invest	10.1177/10406387251382186	2025
	Identification of putative adhesins of Actinobacillus suis and their homologues in other members of the family Pasteurellaceae.	Bujold AR, MacInnes JI.	BMC Res Notes	10.1186/s13104-015-1659-x	2015
Enzymology	Novel DNA Markers for Identification of Actinobacillus pleuropneumoniae.	Srijuntongsiri G, Mhoowai A, Samngamnim S, Assavacheep P, Bosse JT, Langford PR, Posayapisit N, Leartsakulpanich U, Songsungthong W.	Microbiol Spectr	10.1128/spectrum.01311-21	2022
Metabolism	The availability of purine nucleotides regulates natural competence by controlling translation of the competence activator Sxy.	Sinha S, Mell J, Redfield R.	Mol Microbiol	10.1111/mmi.12245	2013
	Comparative pathogenicity of different Actinobacillus suis O/K serotypes.	Slavic D, DeLay J, Hayes MA, MacInnes JI.	Can J Vet Res		2000
Enzymology	Isolation of Actinobacillus suis from a cat's lung.	Daignault D, Chouinard L, Moller K, Ahrens P, Messier S, Higgins R.	Can Vet J		1999
Enzymology	Actinobacillus suis strains isolated from healthy and diseased swine are clonal and carry apxICABDvar. suis and apxIICAvar. suis toxin genes.	Van Ostaaijen J, Frey J, Rosendal S, MacInnes JI.	J Clin Microbiol	10.1128/jcm.35.5.1131-1137.1997	1997
	Evaluation and field validation of PCR tests for detection of Actinobacillus pleuropneumoniae in subclinically infected pigs.	Fittipaldi N, Broes A, Harel J, Kobisch M, Gottschalk M.	J Clin Microbiol	10.1128/jcm.41.11.5085-5093.2003	2003
	Phylogeny of 54 representative strains of species in the family Pasteurellaceae as determined by comparison of 16S rRNA sequences.	Dewhirst FE, Paster BJ, Olsen I, Fraser GJ.	J Bacteriol	10.1128/jb.174.6.2002-2013.1992	1992
	Analysis of major antigens of Haemophilus (Actinobacillus) pleuropneumoniae and related organisms.	MacInnes JI, Rosendal S.	Infect Immun	10.1128/iai.55.7.1626-1634.1987	1987
Phylogeny	Serology of oral Actinobacillus actinomycetemcomitans and serotype distribution in human periodontal disease.	Zambon JJ, Slots J, Genco RJ.	Infect Immun	10.1128/iai.41.1.19-27.1983	1983
	Cellular fatty acid and soluble protein composition of Actinobacillus actinomycetemcomitans and related organisms.	Calhoon DA, Mayberry WR, Slots J.	J Clin Microbiol	10.1128/jcm.14.4.376-382.1981	1981
	Construction of a DNA probe and detection of Actinobacillus pleuropneumoniae by using polymerase chain reaction.	Sirois M, Lemire EG, Levesque RC.	J Clin Microbiol	10.1128/jcm.29.6.1183-1187.1991	1991
Enzymology	Enzymatic characterization of some oral and nonoral gram-negative bacteria with the API ZYM system.	Slots J.	J Clin Microbiol	10.1128/jcm.14.3.288-294.1981	1981
	Compilation of small ribosomal subunit RNA structures.	Neefs JM, Van de Peer Y, De Rijk P, Chapelle S, De Wachter R.	Nucleic Acids Res	10.1093/nar/21.13.3025	1993
Phylogeny	Analysis of non-porcine isolates of Actinobacillus suis.	Jeannotte ME, Slavic D, Frey J, Kuhnert P, MacInnes JI	Vet Microbiol	10.1016/s0378-1135(01)00484-9	2002
	Synergistic effects of Actinobacillus suis cells in combination with 5-fluorouracil on mice bearing murine L1210 leukemia cells.	Watanabe T, Itoh S	Cancer Immunol Immunother	10.1007/s002620050376	1997

References

#8309	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 19774
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68377	Automatically annotated from API NH .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Actinobacillus suis (DSM 19774, ATCC 15557, JCM 2433)

Name and taxonomic classification

Morphology

Cell morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Compound production

Metabolite utilization

Metabolite production

Metabolite tests

Enzymes

API NH

Isolation, sampling and environmental information

Isolation source categories

Isolation

Taxonmaps

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_002081685

16S sequences

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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