Micromonospora carbonacea (DSM 43815, ATCC 27115, IFO 14107)

Name: Micromonospora carbonacea (DSM 43815, ATCC 27115, IFO 14107)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 7884

Type strain

Culture col. no. DSM 43815 ATCC 27115 IFO 14107 JCM 3168 KCC A-0168 10 more

NCBI tax ID(s) 3454472

Special Collections DSMZ JCM KCTC JMRC

History DSMZ <- NRRL <- A. Woyciesjes JCM <-- KCC A-0168 <-- NRRL 2997 <-- Schering Corp..

Links

Micromonospora carbonacea DSM 43815 is a bacterium that was isolated from soil.

genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 38818

MTCC 1054,ATCC 27115,NRRL 2997,DSM 43815,JCM 3168,IFO 14107,CCRC 12628,NCIMB 12664,KCTC 9547,NBRC 14107,BCRC 12628

@ref 20215

Last LPSN update 2026-05-29 08:26:45

Domain Bacteria

Phylum Actinomycetota

Class Actinomycetes

Order Micromonosporales

Family Micromonosporaceae

Genus Micromonospora

Species Micromonospora carbonacea

Full scientific name Micromonospora carbonacea Luedemann and Brodsky 1965 (Approved Lists 1980)

Synonyms (1)

Micromonospora carbonacea subsp. aurantiaca

Morphology

Cell morphology

@ref	Confidence	Gram stain
125439	97.165
125439	99.814	positive
125438	91.5
125438	91.316	positive

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
11288	YEAST-STARCH-AGAR(B) (DSMZ Medium 656)	Medium recipe at MediaDive	Name: YEAST-STARCH-AGAR(B) (DSMZ Medium 656) Composition: Starch 15.0 g/l Agar 15.0 g/l Yeast extract 4.0 g/l MgSO4 x 7 H2O 0.5 g/l K2HPO4 0.5 g/l Distilled water
11288	GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)	Medium recipe at MediaDive	Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 20.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water
11288	N-Z-AMINE-MEDIUM (DSMZ Medium 554)	Medium recipe at MediaDive	Name: N-Z-AMINE-MEDIUM (DSMZ Medium 554) Composition: Starch 20.0 g/l Agar 20.0 g/l Glucose 10.0 g/l N-Z amine 5.0 g/l Yeast extract 5.0 g/l CaCO3 1.0 g/l Distilled water

Culture temp

@ref	Growth	Type	Temperature (°C)
11288	positive	growth	28
67770	positive	growth	28

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
125439	facultative anaerobe	99.346

Spore formation

@ref	Spore formation	Confidence
125438		93.696

Compound production

@ref	Compound
11288	everninomicins
11288	restriction endonuclease McaAI
20216	Everninimycin

Observation

67770

Observationquinones: MK-9(H₄), MK-9(H₆)

Metabolite production

@ref	Chebi-ID	Metabolite	Production
67770	29581 ChEBI	everninomicin

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Environmental	#Terrestrial	#Soil

Isolation

@ref	Sample type
11288	soil
67770	Soil

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
11288	1	Risk group (German classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
124043	ASM1338976v1 assembly for Micromonospora carbonacea subsp. aurantiaca	complete	GCA_013389765	47853.8	8121664990	3454472	95.55
66792	ASM1420516v1 assembly for Micromonospora carbonacea subsp. aurantiaca DSM 43815	contig	GCA_014205165	47853.9	2870855028	47853	75.55

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20218	Micromonospora carbonacea subsp. aurantiaca 16S-23S ribosomal RNA spacer region	AF004001	385		47853
11288	M.carbonacea 16S rRNA gene (isolate DSM 43815)	X92606	1459		47853

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: ASM1338976v1 assembly for Micromonospora carbonacea subsp. aurantiaca
NCBI: GCA_013389765

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	facultative anaerobe	99.35	no
125439	gram_stain	BacteriaNetⓘ	positive	99.81	no
125439	motility	BacteriaNetⓘ	no	97.17	no
125439	spore_formation	BacteriaNetⓘ	yes	76.82	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Micromonospora carbonacea strain aurantiaca
PATRIC: 47853.8

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	91.32	no
125438	anaerobic	anaerobicⓘ	no	93.93	no
125438	spore-forming	spore-formingⓘ	yes	93.70	no
125438	aerobic	aerobicⓘ	yes	86.84	no
125438	thermophilic	thermophileⓘ	no	92.48	no
125438	flagellated	motile2+ⓘ	no	91.50	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Genetics	Metabolomic and genomic insights into Micromonospora carbonacea subsp. caeruleus for anti-colorectal compound.	Kongsaya T, Emthomya N, Ngamcharungchit C, Aroonsri A, Uawisetwathana U, Pruksatrakul T, Euanorasetr J, Intra B.	Appl Microbiol Biotechnol	10.1007/s00253-025-13427-z	2025
Metabolism	The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains.	Starbird CA, Perry NA, Chen Q, Berndt S, Yamakawa I, Loukachevitch LV, Limbrick EM, Bachmann BO, Iverson TM, McCulloch KM.	Biochemistry	10.1021/acs.biochem.8b00836	2018
Metabolism	A two-component system MCNtrB/MCNtrC related to nitrogen metabolism in Micromonospora carbonacea.	Xiang W, Long Y, Zheng X, Ni H, Zou L, Huang Y, Long ZE.	FEMS Microbiol Lett	10.1093/femsle/fnaf016	2025
	Characterization of Dichloroisoeverninic Acid Biosynthesis and Chemoenzymatic Synthesis of New Orthosomycins.	Ynigez-Gutierrez AE, Wurm JE, Froese JT, Rosenthal NE, Bachmann BO.	ACS Chem Biol	10.1021/acschembio.3c00693	2024
	De Novo Whole-Genome Sequence of Micromonospora carbonacea JXNU-1 with Broad-Spectrum Antimicrobial Activity, Isolated from Soil Samples.	Jiang Y, Huang YH, Long ZE.	Genome Announc	10.1128/genomea.00174-15	2015
Metabolism	Bifunctional Nitrone-Conjugated Secondary Metabolite Targeting the Ribosome.	Limbrick EM, Graf M, Derewacz DK, Nguyen F, Spraggins JM, Wieland M, Ynigez-Gutierrez AE, Reisman BJ, Zinshteyn B, McCulloch KM, Iverson TM, Green R, Wilson DN, Bachmann BO.	J Am Chem Soc	10.1021/jacs.0c04675	2020
Phylogeny	The epithet aurantiaca in Micromonospora aurantiaca Sveshnikova et al. 1969 (Approved Lists 1980) is illegitimate and requires a replacement epithet. Opinion 89. Judicial Commission of the International Committee on Systematics of Prokaryotes.	Tindall BJ.	Int J Syst Evol Microbiol	10.1099/ijs.0.069153-0	2014
Metabolism	Biosynthesis of the Thiopeptins and Identification of an F₄₂₀H₂-Dependent Dehydropiperidine Reductase.	Ichikawa H, Bashiri G, Kelly WL.	J Am Chem Soc	10.1021/jacs.8b04238	2018
Metabolism	Isolation and screening of potential actinobacteria for rapid composting of rice straw.	Kausar H, Sariah M, Saud HM, Alam MZ, Ismail MR.	Biodegradation	10.1007/s10532-010-9407-3	2011
	Heterologous Expression of a Cryptic Gene Cluster from Streptomyces leeuwenhoekii C34^T Yields a Novel Lasso Peptide, Leepeptin.	Gomez-Escribano JP, Castro JF, Razmilic V, Jarmusch SA, Saalbach G, Ebel R, Jaspars M, Andrews B, Asenjo JA, Bibb MJ.	Appl Environ Microbiol	10.1128/aem.01752-19	2019
Metabolism	Salinipyrone and Pacificanone Are Biosynthetic By-products of the Rosamicin Polyketide Synthase.	Awakawa T, Crusemann M, Munguia J, Ziemert N, Nizet V, Fenical W, Moore BS.	Chembiochem	10.1002/cbic.201500177	2015
	Development of the Micromonospora carbonacea var. africana ATCC 39149 bacteriophage pMLP1 integrase for site-specific integration in Micromonospora spp.	Alexander DC, Devlin DJ, Hewitt DD, Horan AC, Hosted TJ.	Microbiology (Reading)	10.1099/mic.0.26318-0	2003
	Insights into the phylogenetic diversity, biological activities, and biosynthetic potential of mangrove rhizosphere Actinobacteria from Hainan Island.	Ye JJ, Zou RJ, Zhou DD, Deng XL, Wu NL, Chen DD, Xu J.	Front Microbiol	10.3389/fmicb.2023.1157601	2023
Metabolism	Function of cytochrome P450 enzymes RosC and RosD in the biosynthesis of rosamicin macrolide antibiotic produced by Micromonospora rosaria.	Iizaka Y, Higashi N, Ishida M, Oiwa R, Ichikawa Y, Takeda M, Anzai Y, Kato F.	Antimicrob Agents Chemother	10.1128/aac.02092-12	2013
Enzymology	Characterization of the biosynthetic gene cluster for the oligosaccharide antibiotic, Evernimicin, in Micromonospora carbonacea var. africana ATCC39149.	Hosted TJ, Wang TX, Alexander DC, Horan AC.	J Ind Microbiol Biotechnol	10.1038/sj.jim.7000189	2001
Pathogenicity	Ziracin, a novel oligosaccharide antibiotic.	Ganguly AK.	J Antibiot (Tokyo)	10.7164/antibiotics.53.1038	2000
	Pharmacologic and bacteriologic properties of SCH-27899 (Ziracin), an investigational antibiotic from the everninomicin family.	Foster DR, Rybak MJ.	Pharmacotherapy	10.1592/phco.19.15.1111.30576	1999
Phylogeny	Intrageneric relationships among Micromonospora species deduced from gyrB-based phylogeny and DNA relatedness.	Kasai H, Tamura T, Harayama S.	Int J Syst Evol Microbiol	10.1099/00207713-50-1-127	2000
	Biological control of Sclerotinia minor using a chitinolytic bacterium and actinomycetes.	El-Tarabily KA, Soliman MH, Nassar AH, Al-Hassani HA, Sivasithamparam K, McKenna F, Hardy GESJ.	Plant Pathol	10.1046/j.1365-3059.2000.00494.x	2000
Metabolism	Antibiotics from microbes: converging to kill.	Fischbach MA.	Curr Opin Microbiol	10.1016/j.mib.2009.07.002	2009
Enzymology	Uncovering the potential of novel micromonosporae isolated from an extreme hyper-arid Atacama Desert soil.	Carro L, Castro JF, Razmilic V, Nouioui I, Pan C, Igual JM, Jaspars M, Goodfellow M, Bull AT, Asenjo JA, Klenk HP.	Sci Rep	10.1038/s41598-019-38789-z	2019
Metabolism	Cdc48-like protein of actinobacteria (Cpa) is a novel proteasome interactor in mycobacteria and related organisms.	Ziemski M, Jomaa A, Jomaa A, Mayer D, Rutz S, Giese C, Veprintsev D, Weber-Ban E.	Elife	10.7554/elife.34055	2018
	Biological Control of Mango Dieback Disease Caused by Lasiodiplodia theobromae Using Streptomycete and Non-streptomycete Actinobacteria in the United Arab Emirates.	Kamil FH, Saeed EE, El-Tarabily KA, AbuQamar SF.	Front Microbiol	10.3389/fmicb.2018.00829	2018
Phylogeny	Genome-based classification of micromonosporae with a focus on their biotechnological and ecological potential.	Carro L, Nouioui I, Sangal V, Meier-Kolthoff JP, Trujillo ME, Montero-Calasanz MDC, Sahin N, Smith DL, Kim KE, Peluso P, Deshpande S, Woyke T, Shapiro N, Kyrpides NC, Klenk HP, Goker M, Goodfellow M.	Sci Rep	10.1038/s41598-017-17392-0	2018
Metabolism	Regulation of the biosynthesis of the macrolide antibiotic spiramycin in Streptomyces ambofaciens.	Karray F, Darbon E, Nguyen HC, Gagnat J, Pernodet JL.	J Bacteriol	10.1128/jb.00712-10	2010
Genetics	Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules.	Kersten RD, Ziemert N, Gonzalez DJ, Duggan BM, Nizet V, Dorrestein PC, Moore BS.	Proc Natl Acad Sci U S A	10.1073/pnas.1315492110	2013
	Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.	McCulloch KM, McCranie EK, Smith JA, Sarwar M, Mathieu JL, Gitschlag BL, Du Y, Bachmann BO, Iverson TM.	Proc Natl Acad Sci U S A	10.1073/pnas.1500964112	2015
	Genetic dissection of the biosynthetic route to gentamicin A2 by heterologous expression of its minimal gene set.	Park JW, Hong JS, Parajuli N, Jung WS, Park SR, Lim SK, Sohng JK, Yoon YJ.	Proc Natl Acad Sci U S A	10.1073/pnas.0803164105	2008
Enzymology	Chitinases: An update.	Hamid R, Khan MA, Ahmad M, Ahmad MM, Abdin MZ, Musarrat J, Javed S.	J Pharm Bioallied Sci	10.4103/0975-7406.106559	2013
Cultivation	CHEMISTRY OF ANTIBIOTICS FROM MICROMONOSPORA. 3. ISOLATION AND CHARACTERIZATION OF EVERNINOMICIN D AND B.	HERZOG HL, MESECK E, DELORENZO S, MURAWSKI A, CHARNEY W, ROSSELET JP.	Appl Microbiol	10.1128/am.13.4.515-520.1965	1965
Metabolism	Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.	Zhang H, White-Phillip JA, Melancon CE, Kwon HJ, Yu WL, Liu HW.	J Am Chem Soc	10.1021/ja0744854	2007
	Micromonospora oryzae sp. nov., isolated from roots of upland rice.	Kittiwongwattana C, Thanaboripat D, Laosinwattana C, Koohakan P, Parinthawong N, Thawai C.	Int J Syst Evol Microbiol	10.1099/ijsem.0.000500	2015
Phylogeny	In Silico Analysis of PKS and NRPS Gene Clusters in Arisostatin- and Kosinostatin-Producers and Description of Micromonospora okii sp. nov.	Komaki H, Ichikawa N, Hosoyama A, Hamada M, Igarashi Y.	Antibiotics (Basel)	10.3390/antibiotics10121447	2021
Phylogeny	Micromonospora mirobrigensis sp. nov.	Trujillo ME, Fernandez-Molinero C, Velazquez E, Kroppenstedt RM, Schumann P, Mateos PF, Martinez-Molina E.	Int J Syst Evol Microbiol	10.1099/ijs.0.63361-0	2005
Phylogeny	Micromonospora haikouensis sp. nov., isolated from mangrove soil.	Xie QY, Qu Z, Lin HP, Li L, Hong K	Antonie Van Leeuwenhoek	10.1007/s10482-011-9682-y	2012

References

#11288	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 43815
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20216	Curators of the JMRC: Jena Microbial Resource Collection (JMRC):
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

Rate our new design

Content

About us

Micromonospora carbonacea (DSM 43815, ATCC 27115, IFO 14107)

Name and taxonomic classification

Morphology

Cell morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Compound production

Observation

Metabolite production

Isolation, sampling and environmental information

Isolation source categories

Isolation

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_013389765

16S sequences

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

Help

Social Media