Bilophila wadsworthia RZATAU is an anaerobe, mesophilic human pathogen that was isolated from anaerobic mud, sewage plant.
anaerobe mesophilic human pathogen 16S sequence| @ref 20215 |
Last LPSN update
2025-12-16 09:47:43 |
| Domain Pseudomonadati |
| Phylum Thermodesulfobacteriota |
| Class Desulfovibrionia |
| Order Desulfovibrionales |
| Family Desulfovibrionaceae |
| Genus Bilophila |
| Species Bilophila wadsworthia |
| Full scientific name Bilophila wadsworthia Baron et al. 1990 |
| BacDive ID | Other strains from Bilophila wadsworthia (6) | Type strain |
|---|---|---|
| 146880 | B. wadsworthia CCUG 32349, ATCC 49260 (type strain) | |
| 151266 | B. wadsworthia CCUG 43589 | |
| 151302 | B. wadsworthia CCUG 43686 | |
| 151841 | B. wadsworthia CCUG 45035 | |
| 151848 | B. wadsworthia CCUG 45045 | |
| 160478 | B. wadsworthia Cla-CZ-104, DSM 109342 |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 4167 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | Medium recipe at MediaDive  | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base | ||
| 4167 | FASTIDIOUS ANAEROBE AGAR (DSMZ Medium 1203) | Medium recipe at MediaDive | Name: FASTIDIOUS ANAEROBE AGAR (DSMZ Medium 1203) Composition: Horse blood 100.0 g/l Fastidious Anaerobe Agar 45.7 g/l Distilled water | ||
| 4167 | ANAEROBIC FRESHWATER (FWM) MEDIUM (DSMZ Medium 503) | Medium recipe at MediaDive | Name: ANAEROBIC FRESHWATER (FWM) MEDIUM (DSMZ Medium 503; with strain-specific modifications) Composition: D-Glucose 4.98504 g/l Na-formate 4.08043 g/l Na2CO3 1.49551 g/l Taurine 1.25148 g/l NaCl 0.997008 g/l KCl 0.498505 g/l MgCl2 x 6 H2O 0.398803 g/l Na2S x 9 H2O 0.299103 g/l NH4Cl 0.249252 g/l KH2PO4 0.199402 g/l CaCl2 x 2 H2O 0.149552 g/l HCl 0.00249252 g/l FeCl2 x 4 H2O 0.00149551 g/l Sodium resazurin 0.000498505 g/l NaOH 0.000498504 g/l Pyridoxine hydrochloride 0.000299103 g/l Nicotinic acid 0.000199402 g/l Thiamine-HCl x 2 H2O 0.000199402 g/l CoCl2 x 6 H2O 0.000189432 g/l MnCl2 x 4 H2O 9.97009e-05 g/l Vitamin B12 9.97009e-05 g/l Calcium pantothenate 9.97009e-05 g/l p-Aminobenzoic acid 7.97607e-05 g/l ZnCl2 6.97906e-05 g/l Na2MoO4 x 2 H2O 3.58923e-05 g/l NiCl2 x 6 H2O 2.39282e-05 g/l D-(+)-biotin 1.99402e-05 g/l H3BO3 5.98205e-06 g/l Na2WO4 x 2 H2O 3.98804e-06 g/l Na2SeO3 x 5 H2O 2.99103e-06 g/l CuCl2 x 2 H2O 1.99402e-06 g/l 1,4-Naphthoquinone Distilled water |
| @ref | Growth | Type | Temperature (°C) | Range | |
|---|---|---|---|---|---|
| 4167 | positive | growth | 37 | mesophilic |
| Cat1 | Cat2 | Cat3 | |
|---|---|---|---|
| #Engineered | #Waste | #Water treatment plant | |
| #Environmental | #Terrestrial | #Mud (Sludge) | |
| #Condition | #Anoxic (anaerobic) | - |
| @ref | Sample type | Country | Country ISO 3 Code | Continent | |
|---|---|---|---|---|---|
| 4167 | anaerobic mud, sewage plant | Germany | DEU | Europe |
Global distribution of 16S sequence AB117562 (>99% sequence identity) for Bilophila wadsworthia subclade from Microbeatlas 
 Aquatic Samples |
7361 |
 Soil Samples |
2066 |
 Animal Samples |
238547 |
 Plant Samples |
713 |
| Total Samples | 248687 |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 4167 | Bilophila wadsworthia gene for 16S rRNA, partial sequence, strain:NB-12 | AB117562 | 1445 |   | 35833 |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Bacterial microcompartments and energy metabolism drive gut colonization by Bilophila wadsworthia | Sayavedra L, Yasir M, Goldson A, Brion A, Le Gall G, Moreno-Gonzalez M, Altera A, Paxhia M, Warren M, Savva G, Turner A, Beraza N, Narbad A. | Nat Commun | 2025 |  | ||
| Bacterial cysteate dissimilatory pathway involves a racemase and d-cysteate sulfo-lyase. | Liu C, Ma K, Jiang L, Liu X, Tong Y, Yang S, Jin X, Wei Y, Zhang Y. | J Biol Chem | 10.1016/j.jbc.2024.107371 | 2024 | | |
| Isethionate is an intermediate in the degradation of sulfoacetate by the human gut pathobiont Bilophila wadsworthia. | Liu X, Wei Y, Zhang J, Zhou Y, Du Y, Zhang Y. | J Biol Chem | 10.1016/j.jbc.2023.105010 | 2023 | | |
| Metabolism | Study of sulfoglycolysis in Enterococcus gilvus reveals a widespread bifurcated pathway for dihydroxypropanesulfonate degradation. | Chen Y, Chu R, Ma K, Jiang L, Yang Q, Li Z, Hu M, Guo Q, Lu F, Wei Y, Zhang Y, Tong Y. | iScience | 10.1016/j.isci.2024.111010 | 2024 | |
| Multiplexed Quantitative Assessment of the Fate of Taurine and Sulfoquinovose in the Intestinal Microbiome. | Haange SB, Groeger N, Froment J, Rausch T, Burkhardt W, Gonnermann S, Braune A, Blaut M, von Bergen M, Rolle-Kampczyk U. | Metabolites | 10.3390/metabo10110430 | 2020 | | |
| Sulfoquinovose is a select nutrient of prominent bacteria and a source of hydrogen sulfide in the human gut. | Hanson BT, Dimitri Kits K, Loffler J, Burrichter AG, Fiedler A, Denger K, Frommeyer B, Herbold CW, Rattei T, Karcher N, Segata N, Schleheck D, Loy A. | ISME J | 10.1038/s41396-021-00968-0 | 2021 | | |
| Phylogeny | Berberine alters gut microbial function through modulation of bile acids. | Wolf PG, Devendran S, Doden HL, Ly LK, Moore T, Takei H, Nittono H, Murai T, Kurosawa T, Chlipala GE, Green SJ, Kakiyama G, Kashyap P, McCracken VJ, Gaskins HR, Gillevet PM, Ridlon JM. | BMC Microbiol | 10.1186/s12866-020-02020-1 | 2021 | |
| Metabolism | Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria. | Xing M, Wei Y, Zhou Y, Zhang J, Lin L, Hu Y, Hua G, N Nanjaraj Urs A, Liu D, Wang F, Guo C, Tong Y, Li M, Liu Y, Ang EL, Zhao H, Yuchi Z, Zhang Y. | Nat Commun | 10.1038/s41467-019-09618-8 | 2019 | |
| Metabolism | Two radical-dependent mechanisms for anaerobic degradation of the globally abundant organosulfur compound dihydroxypropanesulfonate. | Liu J, Wei Y, Lin L, Teng L, Yin J, Lu Q, Chen J, Zheng Y, Li Y, Xu R, Zhai W, Liu Y, Liu Y, Cao P, Ang EL, Zhao H, Yuchi Z, Zhang Y. | Proc Natl Acad Sci U S A | 10.1073/pnas.2003434117 | 2020 | |
| Metabolism | L-cysteate sulpho-lyase, a widespread pyridoxal 5'-phosphate-coupled desulphonative enzyme purified from Silicibacter pomeroyi DSS-3(T). | Denger K, Smits TH, Cook AM. | Biochem J | 10.1042/bj20051311 | 2006 | |
| Metabolism | Sulphoacetaldehyde acetyltransferase yields acetyl phosphate: purification from Alcaligenes defragrans and gene clusters in taurine degradation. | Ruff J, Denger K, Cook AM. | Biochem J | 10.1042/bj20021455 | 2003 | |
| Metabolism | The 'in vivo lifestyle' of bile acid 7alpha-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined microbial community in gnotobiotic mice. | Ridlon JM, Devendran S, Alves JM, Doden H, Wolf PG, Pereira GV, Ly L, Volland A, Takei H, Nittono H, Murai T, Kurosawa T, Chlipala GE, Green SJ, Hernandez AG, Fields CJ, Wright CL, Kakiyama G, Cann I, Kashyap P, McCracken V, Gaskins HR | Gut Microbes | 10.1080/19490976.2019.1618173 | 2019 | |
| Enzymology | Dissimilatory sulfite reductase (desulfoviridin) of the taurine-degrading, non-sulfate-reducing bacterium Bilophila wadsworthia RZATAU contains a fused DsrB-DsrD subunit. | Laue H, Friedrich M, Ruff J, Cook AM | J Bacteriol | 10.1128/JB.183.5.1727-1733.2001 | 2001 | |
| Metabolism | Biochemical and molecular characterization of taurine:pyruvate aminotransferase from the anaerobe Bilophila wadsworthia. | Laue H, Cook AM | Eur J Biochem | 10.1046/j.1432-1033.2000.01782.x | 2000 | |
| Enzymology | Purification, properties and primary structure of alanine dehydrogenase involved in taurine metabolism in the anaerobe Bilophila wadsworthia. | Laue H, Cook AM | Arch Microbiol | 10.1007/s002030000190 | 2000 | |
| Metabolism | Taurine reduction in anaerobic respiration of Bilophila wadsworthia RZATAU. | Laue H, Denger K, Cook AM | Appl Environ Microbiol | 10.1128/aem.63.5.2016-2021.1997 | 1997 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive4068.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
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