Corynebacterium propinquum (JCM 12106, DSM 44285, ATCC 51488)

Name: Corynebacterium propinquum (JCM 12106, DSM 44285, ATCC 51488)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 3172

Type strain

Strain Designation Riegel B 77159, B 77159

Culture col. no. JCM 12106 DSM 44285 ATCC 51488 CCUG 33048 CIP 103792 3 more

NCBI tax ID(s) 1121367 43769

Special Collections DSMZ CCUG JCM CIP Wink compendium Literature strains

History <- CCUG <- P. Riegel, ULP Strasbourg, B 77159 1993, H. Monteil, Strasbourg Hosp., France: strain B 77159 CCUG 33048 <-- P. Riegel B 77159. CIP <- 1993, H. Monteil, Strasbourg Hosp., Strasbourg, France: strain B 77159

Links

Corynebacterium propinquum Riegel B 77159 is an obligate aerobe, mesophilic, Gram-positive prokaryote that was isolated from human respiratory tract.

Gram-positive rod-shaped obligate aerobe mesophilic genome sequence 16S sequence

Name and taxonomic classification

SI-ID 13102

LMG 19069,ATCC 51488,CCUG 33048,CIP 103792,DSM 44285,JCM 12106

@ref 20215

Last LPSN update 2026-02-09 11:18:26

Domain Bacteria

Phylum Actinomycetota

Class Actinomycetes

Order Mycobacteriales

Family Corynebacteriaceae

Genus Corynebacterium

Species Corynebacterium propinquum

Full scientific name Corynebacterium propinquum Riegel et al. 1994

BacDive ID	Other strains from **Corynebacterium propinquum** (7)	Type strain
3173	C. propinquum Riegel B 65299, DSM 44286, CCUG 33049
146812	C. propinquum CCUG 32163
146941	C. propinquum CCUG 32509
147206	C. propinquum CCUG 33050
147207	C. propinquum CCUG 33051
151717	C. propinquum CCUG 44703
156456	C. propinquum CCUG 61888

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Confidence
23176	positive	rod-shaped
121963	positive	rod-shaped
125438			94
125438	positive		91.817

Colony morphology

@ref	Colony color	Incubation period	Medium used
19644	Beige	10-14 days	ISP 2
19644	Beige	10-14 days	ISP 3
19644	Beige	10-14 days	ISP 4
19644	Beige	10-14 days	ISP 5
19644	Beige	10-14 days	ISP 6
19644	Beige	10-14 days	ISP 7
23176		1 day

Multicellular morphology

@ref	Forms multicellular complex	Medium name
19644		ISP 2
19644		ISP 3
19644		ISP 4
19644		ISP 5
19644		ISP 6
19644		ISP 7

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
11532	TRYPTICASE SOY BROTH AGAR (DSMZ Medium 535)	Medium recipe at MediaDive	Name: TRYPTICASE SOY BROTH AGAR (DSMZ Medium 535; with strain-specific modifications) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Tween 80 2.0 g/l Distilled water
11532	TRYPTICASE SOY BROTH AGAR+BLOOD (DSMZ Medium 535a)	Medium recipe at MediaDive	Name: TRYPTICASE SOY BROTH AGAR+BLOOD (DSMZ Medium 535a) Composition: None 50.0 g/l Trypticase soy broth 30.0 g/l Agar 15.0 g/l Distilled water
19644	ISP 2		Name: ISP 2 / Yeast Malt Agar (5265); 5265 Composition Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l Agar 15.0 g/l Preparation: Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.0 Usage: Maintenance and Taxonomy Organisms: All Actinomycetes
19644	ISP 3		Name: ISP 3; 5315 Composition Dog oat flakes 20.0 g/l Trace element solution (5314) 2.5 ml/l Agar 18.0 g/l Preparation: Oat flakes are cooked for 20 minutes, trace element solution and agar are added (in the case of non rolled oat flakes the suspension has to bee filtrated). Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.8 Usage: Maintenance and taxonomy (e.g. SEM As liquid medium for metabolite production) Organisms: All Actinomycetes Trace element solution 5314 Name: Trace element solution 5314; 5314 Composition CaCl2 x H2O 3.0 g/l Fe-III-citrate 1.0 g/l MnSO4 0.2 g/l ZnCl2 0.1 g/l CuSO4 x 5 H2O 0.025 g/l Sodium tetra borate 0.2 g/l CoCl2 x 6 H2O 0.004 g/l Sodium molybdate 0.01 g/l Preparation: Use double destillated water. Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Trace element solution for different media Organisms:
19644	ISP 4		Name: ISP 4; DSM 547 Solution I: Difco soluble starch, 10.0 g. Make a paste of the starch with a small amount of cold distilled water and bring to a volume of 500 ml. Solution II: CaCO3 2.0 g K2HPO4 (anhydrous) 1.0 g MgSO4 x 7 H2O 1.0 g NaCl 1.0 g (NH4)2SO4 2.0 g Distilled water 500.0 ml Trace salt solution (see below) 1.0 ml The pH should be between 7.0 and 7.4. Do not adjust if it is within this range. Mix solutions I and II together. Add 20.0 g agar. Liquify agar by steaming at 100°C for 10 to 20 min. Trace element solution: FeSO4 x 7 H2O 0.1 g MnCl2 x 4 H2O 0.1 g ZnSO4 x 7 H2O 0.1 g Distilled water 100.0 ml
19644	ISP 5		Name: ISP 5 (5323) Composition L-Asparagine 1.0 g/l Glycerol 10.0 g/l K2HPO4 1.0 g/l Salt solution (see preparation) 1.0 ml/l Agar 20.0 g/l Preparation: Salt solution 1.0 g FeSO4 x 7 H2O 1.0 g MnCl2 x 4 H2O 1.0 g ZNSO4 x 7 H2O in 100 ml water Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.2 Usage: Maintenance and taxonomy Organisms: All Actinomycetes
19644	ISP 6		Name: ISP 6 (5318) Composition Peptone 15.0 g/l Proteose peptose 5.0 g/l Ferric ammonium citrate 0.5 g/l Sodium glycerophosphate 1.0 g/l Sodium thiosulfate 0.08 g/l Yeast extract 1.0 g/l Agar 15.0 g/l Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Production of melanoid pigments Organisms: All Actinomycetes
19644	ISP 7		Name: ISP 7 (5322) Composition Glycerol 15.0 g/l L-Tyrosine 0.5 g/l L-Asparagine 1.0 g/l K2HPO4 0.5 g/l NaCl 0.5 g/l FeSO4 x 7 H2O 0.01 g/l Trace element solution 5343 1.0 ml/l Agar 20.0 Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.3 Usage: Production of melanoid pigments Organisms: All Actinomycetes
38156	MEDIUM 3 - Columbia agar		Columbia agar (39.000 g);distilled water (1000.000 ml)
121963	CIP Medium 72	Medium recipe at CIP
121963	CIP Medium 3	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
11532	positive	growth	37	mesophilic
19644	positive	optimum	37	mesophilic
23176	positive	growth	25-37	mesophilic
23176	negative	growth	42
38156	positive	growth	37	mesophilic
67770	positive	growth	37	mesophilic
121963	positive	growth	37	mesophilic
121963	negative	growth	5
121963	negative	growth	41

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
121963	obligate aerobe
125439	microaerophile	93.3

Spore formation

@ref	Spore formation	Confidence
121963
125439		97

Halophily

@ref	Salt	Growth	Tested relation	Concentration
121963	NaCl	positive	growth	6.5 %

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68379	17634 ChEBI	D-glucose	-	fermentation	from API Coryne
68379	16899 ChEBI	D-mannitol	-	fermentation	from API Coryne
68379	16988 ChEBI	D-ribose	-	fermentation	from API Coryne
68379	65327 ChEBI	D-xylose	-	fermentation	from API Coryne
68379	4853 ChEBI	esculin	-	hydrolysis	from API Coryne
121963	4853 ChEBI	esculin	-	hydrolysis
68379	5291 ChEBI	gelatin	-	hydrolysis	from API Coryne
68379	28087 ChEBI	glycogen	-	fermentation	from API Coryne
68379	17716 ChEBI	lactose	-	fermentation	from API Coryne
68379	17306 ChEBI	maltose	-	fermentation	from API Coryne
23176	17632 ChEBI	nitrate	-	reduction
68379	17632 ChEBI	nitrate	-	reduction	from API Coryne
121963	17632 ChEBI	nitrate	+	reduction
121963	17632 ChEBI	nitrate	-	respiration
121963	16301 ChEBI	nitrite	-	reduction
68379	17992 ChEBI	sucrose	+	fermentation	from API Coryne
68379	16199 ChEBI	urea	+	hydrolysis	from API Coryne

Antibiotic resistance

@ref	Metabolite	Is sensitive	Is resistant
121963	0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)

Metabolite production

@ref	Chebi-ID	Metabolite	Production
121963	35581 ChEBI	indole

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Methylred-test
121963	15688 ChEBI	acetoin	-
121963	17234 ChEBI	glucose		-

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
121963	alcohol dehydrogenase	-	1.1.1.1
68379	alkaline phosphatase	-	3.1.3.1	from API Coryne
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	-	3.2.1.20	from API zym
68379	alpha-glucosidase	-	3.2.1.20	from API Coryne
68382	alpha-mannosidase	-	3.2.1.24	from API zym
121963	amylase	-
68382	beta-galactosidase	-	3.2.1.23	from API zym
121963	beta-galactosidase	-	3.2.1.23
68379	beta-galactosidase	-	3.2.1.23	from API Coryne
68382	beta-glucosidase	-	3.2.1.21	from API zym
68379	beta-glucosidase	-	3.2.1.21	from API Coryne
68382	beta-glucuronidase	-	3.2.1.31	from API zym
68379	beta-glucuronidase	-	3.2.1.31	from API Coryne
23176	catalase	+	1.11.1.6
121963	catalase	+	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
23176	cytochrome oxidase	-	1.9.3.1
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
121963	gelatinase	-
68379	gelatinase	-		from API Coryne
68382	leucine arylamidase	+	3.4.11.1	from API zym
121963	lipase	-
121963	lysine decarboxylase	-	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68379	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API Coryne
121963	ornithine decarboxylase	-	4.1.1.17
121963	oxidase	-
23176	pyrazinamidase	+	3.5.1.B15
68379	pyrazinamidase	-	3.5.1.B15	from API Coryne
68379	pyrrolidonyl arylamidase	-	3.4.19.3	from API Coryne
68382	trypsin	-	3.4.21.4	from API zym
121963	urease	-	3.5.1.5
68379	urease	+	3.5.1.5	from API Coryne
68382	valine arylamidase	+		from API zym

API coryne

@ref	Reduction of nitrateNIT	PYZ	PYRA	PAL	beta GUR	beta GAL	alpha GLU	beta NAG	ESC	URE	GEL	Control fermentationControl	GLU	RIB	XYL	MAN	MAL	LAC	SAC	GLYG	CAT
19644	-	-	-	-	-	-	-	-	-	+	-	not determinedn.d.	-	-	-	-	-	-	+	-	not determinedn.d.

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
19644	not determinedn.d.	-	+	+	-	+	+	-	-	-	+	+	-	-	-	-	-	-	-	-
121963	-	+	+	+	+	+	+	-	-	-	+	-	-	-	-	-	-	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Host	#Human	-
#Host Body-Site	#Oral cavity and airways	#Airways

Isolation

@ref	Sample type	Geographic location	Country	Country ISO 3 Code	Continent	Isolation date
11532	human respiratory tract	Strasbourg	France	FRA	Europe
23176	Respiratory tract
51349	Human tracheal aspiration	Strasbourg	France	FRA	Europe
67770	Human respiratory tract
121963	Human, Tracheal aspiration	Strasbourg	France	FRA	Europe	1987

Taxonmaps

69479

Global distribution of 16S sequence X81917 (>99% sequence identity) for Corynebacterium propinquum from Microbeatlas

Aquatic Samples	2462
Soil Samples	2082
Animal Samples	42880
Plant Samples	422
Total Samples	47846

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
11532	2	Risk group (German classification) According to TRBA 466
19644	2	Risk group (german classification) According to TRBA 466
121963	2	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
124043	ASM1672866v1 assembly for Corynebacterium propinquum FDAARGOS_1112	complete	GCA_016728665	43769.22	8120470934	43769	99.3
67770	ASM37552v1 assembly for Corynebacterium propinquum DSM 44285	contig	GCA_000375525	1121367.3	2515154156	1121367	74.65

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Corynebacterium propinquum strain DSM 44285 16S-23S ribosomal RNA intergenic spacer, complete sequence	AF536506	389	1121367
20218	C.propinquum 16S rRNA gene (CIP 103792T)	X81917	1396	1121367
11532	Corynebacterium propinquum partial 16S rRNA gene, strain CIP 103792	X84438	1443	1121367
67770	Corynebacterium propinquum culture-collection NML:91-0122 16S ribosomal RNA gene, partial sequence	JX476064	1444	43769
124043	Corynebacterium propinquum gene for 16S rRNA, partial sequence.	AB470619	542	1121367
124043	Corynebacterium propinquum DNA, 16S-23S ribosomal RNA intergenic spacer, partial sequence.	AB477424	759	1121367
124043	Corynebacterium propinquum CIP 103792 gene for 16S rRNA, partial sequence.	LC752452	573	1121367

GC content

@ref	GC-content (mol%)	Method
67770	57	high performance liquid chromatography (HPLC)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Corynebacterium propinquum DSM 44285
NCBI: GCA_000375525

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	microaerophile	93.30	no
125439	gram_stain	BacteriaNetⓘ	positive	84.40	no
125439	motility	BacteriaNetⓘ	no	71.70	no
125439	spore_formation	BacteriaNetⓘ	no	97.00	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Corynebacterium propinquum strain FDAARGOS_1112 strain Not applicable
PATRIC: 43769.22

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	91.82	yes
125438	anaerobic	anaerobicⓘ	no	95.95	yes
125438	spore-forming	spore-formingⓘ	no	84.88	no
125438	aerobic	aerobicⓘ	yes	69.98	no
125438	thermophilic	thermophileⓘ	no	93.36	yes
125438	flagellated	motile2+ⓘ	no	94.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Emulgel Containing Metronidazole and Clindamycin for the Treatment of Rosacea.	De Grau-Bassal G, Calpena-Campmany AC, Silva-Abreu M, Suner-Carbo J, Mallandrich-Miret M, Martinez-Ruiz S, Cordero C, Del Pozo A, Febrer NB.	Pharmaceutics	10.3390/pharmaceutics17020168	2025
	Diversity of Mycobacteriaceae from aquatic environment at the São Paulo Zoological Park Foundation in Brazil.	Romagnoli CL, Pellegrino KCM, Silva NM, Brianesi UA, Leao SC, Rabello MCDS, Viana-Niero C.	PLoS One	10.1371/journal.pone.0227759	2020
Pathogenicity	Cationic Intrinsically Disordered Antimicrobial Peptides (CIDAMPs) Represent a New Paradigm of Innate Defense with a Potential for Novel Anti-Infectives.	Latendorf T, Gerstel U, Wu Z, Bartels J, Becker A, Tholey A, Schroder JM.	Sci Rep	10.1038/s41598-019-39219-w	2019
Enzymology	Direct detection of Corynebacterium striatum, Corynebacterium propinquum, and Corynebacterium simulans in sputum samples by high-resolution melt curve analysis.	Xu S, Qiu X, Hou X, Zhou H, Chen D, Wang X, Han L, Li D, Sun L, Ji X, Li M, Zhang J, Li M, Li Z.	BMC Infect Dis	10.1186/s12879-020-05633-z	2021
Metabolism	Metabolic capabilities are highly conserved among human nasal-associated Corynebacterium species in pangenomic analyses.	Tran TH, F Escapa I, Roberts AQ, Gao W, Obawemimo AC, Segre JA, Kong HH, Conlan S, Kelly MS, Lemon KP.	mSystems	10.1128/msystems.01132-24	2024
Phylogeny	Pseudomonas mangrovi sp. nov., isolated from mangrove soil.	Ye Y, Chen C, Ren Y, Wang R, Zhang C, Han S, Ju Z, Zhao Z, Sun C, Wu M.	Int J Syst Evol Microbiol	10.1099/ijsem.0.003141	2019
Phylogeny	Taxonomic description and draft genome of Pseudomonas sediminis sp. nov., isolated from the rhizospheric sediment of Phragmites karka.	Behera P, Mahapatra M, Seuylemezian A, Vaishampayan P, Ramana VV, Joseph N, Joshi A, Shouche Y, Suar M, Pattnaik AK, Rastogi G.	J Microbiol	10.1007/s12275-018-7549-x	2018

References

#11532	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 44285
#19644	Wink, J.: Compendium of Actinobacteria. HZI-Helmholtz-Centre for Infection Research, Braunschweig .
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#23176	Kathryn Bernard, Ana Luisa Pacheco, Ian Cunningham, Navdeep Gill, Tamara Burdz, Deborah Wiebe: Emendation of the description of the species Corynebacterium propinquum to include strains which produce urease. IJSEM 63: 2146 - 2154 2013 ( DOI 10.1099/ijs.0.046979-0 , PubMed 23104363 )
#38156	; Curators of the CIP;
#51349	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 33048
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68379	Automatically annotated from API Coryne .
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#121963	Collection of Institut Pasteur ; Curators of the CIP; CIP 103792
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Corynebacterium propinquum (JCM 12106, DSM 44285, ATCC 51488)

Name and taxonomic classification

Morphology

Cell morphology

Colony morphology

Multicellular morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Halophily

Metabolite utilization

Antibiotic resistance

Metabolite production

Metabolite tests

Enzymes

API coryne

API zym

Isolation, sampling and environmental information

Isolation source categories

Isolation

Taxonmaps

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_016728665

16S sequences

GC content

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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