Streptomyces netropsis (DSM 40093, ATCC 19756, CBS 494.68)

Multimedia

• @ref:	9305
  multimedia content:	DSM_40093.jpg
  multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_40093.jpg
  caption:	Medium 65 28°C
  intellectual property rights:	© Leibniz-Institut DSMZ
  manual_annotation:	1

Culture medium

@ref	Name	Growth	Medium link	Composition
9305	GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)		Medium recipe at MediaDive	Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water

Culture temp

Compound production

Metabolite production

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions	external links
66794	cellulose degradation	100	5 of 5
66794	adipate degradation	100	2 of 2
66794	glycolate and glyoxylate degradation	100	6 of 6
66794	phenylacetate degradation (aerobic)	100	5 of 5
66794	aminopropanol phosphate biosynthesis	100	2 of 2
66794	threonine metabolism	100	10 of 10
66794	1,4-dihydroxy-6-naphthoate biosynthesis	100	6 of 6
66794	myo-inositol biosynthesis	100	10 of 10
66794	glycogen metabolism	100	5 of 5
66794	palmitate biosynthesis	100	22 of 22
66794	valine metabolism	100	9 of 9
66794	cis-vaccenate biosynthesis	100	2 of 2
66794	enterobactin biosynthesis	100	3 of 3
66794	molybdenum cofactor biosynthesis	100	9 of 9
66794	cardiolipin biosynthesis	100	7 of 7
66794	ppGpp biosynthesis	100	4 of 4
66794	biotin biosynthesis	100	4 of 4
66794	UDP-GlcNAc biosynthesis	100	3 of 3
66794	reductive acetyl coenzyme A pathway	100	7 of 7
66794	suberin monomers biosynthesis	100	2 of 2
66794	taurine degradation	100	1 of 1
66794	folate polyglutamylation	100	1 of 1
66794	aerobactin biosynthesis	100	1 of 1
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	butanoate fermentation	100	4 of 4
66794	CDP-diacylglycerol biosynthesis	100	2 of 2
66794	ethanol fermentation	100	2 of 2
66794	acetate fermentation	100	4 of 4
66794	glycine betaine biosynthesis	100	5 of 5
66794	formaldehyde oxidation	100	3 of 3
66794	methylglyoxal degradation	100	5 of 5
66794	coenzyme A metabolism	100	4 of 4
66794	glutamate and glutamine metabolism	92.86	26 of 28
66794	leucine metabolism	92.31	12 of 13
66794	phenylalanine metabolism	92.31	12 of 13
66794	pentose phosphate pathway	90.91	10 of 11
66794	starch degradation	90	9 of 10
66794	Entner Doudoroff pathway	90	9 of 10
66794	d-mannose degradation	88.89	8 of 9
66794	NAD metabolism	88.89	16 of 18
66794	serine metabolism	88.89	8 of 9
66794	chorismate metabolism	88.89	8 of 9
66794	aspartate and asparagine metabolism	88.89	8 of 9
66794	gluconeogenesis	87.5	7 of 8
66794	C4 and CAM-carbon fixation	87.5	7 of 8
66794	peptidoglycan biosynthesis	86.67	13 of 15
66794	flavin biosynthesis	86.67	13 of 15
66794	alanine metabolism	86.21	25 of 29
66794	aclacinomycin biosynthesis	85.71	6 of 7
66794	citric acid cycle	85.71	12 of 14
66794	heme metabolism	85.71	12 of 14
66794	ubiquinone biosynthesis	85.71	6 of 7
66794	photosynthesis	85.71	12 of 14
66794	vitamin B12 metabolism	85.29	29 of 34
66794	purine metabolism	82.98	78 of 94
66794	proline metabolism	81.82	9 of 11
66794	metabolism of disaccharids	81.82	9 of 11
66794	metabolism of amino sugars and derivatives	80	4 of 5
66794	factor 420 biosynthesis	80	4 of 5
66794	ethylmalonyl-CoA pathway	80	4 of 5
66794	glutathione metabolism	78.57	11 of 14
66794	CO2 fixation in Crenarchaeota	77.78	7 of 9
66794	allantoin degradation	77.78	7 of 9
66794	pyrimidine metabolism	77.78	35 of 45
66794	lipid metabolism	77.42	24 of 31
66794	urea cycle	76.92	10 of 13
66794	glycolysis	76.47	13 of 17
66794	tryptophan metabolism	76.32	29 of 38
66794	histidine metabolism	75.86	22 of 29
66794	ketogluconate metabolism	75	6 of 8
66794	cyclohexanol degradation	75	3 of 4
66794	isoleucine metabolism	75	6 of 8
66794	glycogen biosynthesis	75	3 of 4
66794	lactate fermentation	75	3 of 4
66794	sulfopterin metabolism	75	3 of 4
66794	arginine metabolism	75	18 of 24
66794	non-pathway related	73.68	28 of 38
66794	methionine metabolism	73.08	19 of 26
66794	tetrahydrofolate metabolism	71.43	10 of 14
66794	propanol degradation	71.43	5 of 7
66794	propionate fermentation	70	7 of 10
66794	4-hydroxyphenylacetate degradation	70	7 of 10
66794	isoprenoid biosynthesis	69.23	18 of 26
66794	oxidative phosphorylation	69.23	63 of 91
66794	vitamin B1 metabolism	69.23	9 of 13
66794	cyanate degradation	66.67	2 of 3
66794	acetoin degradation	66.67	2 of 3
66794	4-hydroxymandelate degradation	66.67	6 of 9
66794	octane oxidation	66.67	2 of 3
66794	lysine metabolism	66.67	28 of 42
66794	degradation of aromatic, nitrogen containing compounds	66.67	8 of 12
66794	cysteine metabolism	66.67	12 of 18
66794	acetyl CoA biosynthesis	66.67	2 of 3
66794	methane metabolism	66.67	2 of 3
66794	IAA biosynthesis	66.67	2 of 3
66794	L-lactaldehyde degradation	66.67	2 of 3
66794	tyrosine metabolism	64.29	9 of 14
66794	cholesterol biosynthesis	63.64	7 of 11
66794	d-xylose degradation	63.64	7 of 11
66794	degradation of sugar alcohols	62.5	10 of 16
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	62.5	5 of 8
66794	dTDPLrhamnose biosynthesis	62.5	5 of 8
66794	coenzyme M biosynthesis	60	6 of 10
66794	vitamin K metabolism	60	3 of 5
66794	glycine metabolism	60	6 of 10
66794	lipoate biosynthesis	60	3 of 5
66794	arachidonate biosynthesis	60	3 of 5
66794	androgen and estrogen metabolism	56.25	9 of 16
66794	daunorubicin biosynthesis	55.56	5 of 9
66794	nitrate assimilation	55.56	5 of 9
66794	vitamin B6 metabolism	54.55	6 of 11
66794	phenylpropanoid biosynthesis	53.85	7 of 13
66794	3-phenylpropionate degradation	53.33	8 of 15
66794	mannosylglycerate biosynthesis	50	1 of 2
66794	ribulose monophosphate pathway	50	1 of 2
66794	pantothenate biosynthesis	50	3 of 6
66794	toluene degradation	50	2 of 4
66794	CMP-KDO biosynthesis	50	2 of 4
66794	grixazone biosynthesis	50	1 of 2
66794	quinate degradation	50	1 of 2
66794	vitamin E metabolism	50	2 of 4
66794	phenylmercury acetate degradation	50	1 of 2
66794	polyamine pathway	47.83	11 of 23
66794	bile acid biosynthesis, neutral pathway	47.06	8 of 17
66794	phosphatidylethanolamine bioynthesis	46.15	6 of 13
66794	phenol degradation	45	9 of 20
66794	lipid A biosynthesis	44.44	4 of 9
66794	degradation of hexoses	44.44	8 of 18
66794	benzoyl-CoA degradation	42.86	3 of 7
66794	carotenoid biosynthesis	40.91	9 of 22
66794	3-chlorocatechol degradation	40	2 of 5
66794	elloramycin biosynthesis	40	2 of 5
66794	gallate degradation	40	2 of 5
66794	bacilysin biosynthesis	40	2 of 5
66794	degradation of pentoses	39.29	11 of 28
66794	chlorophyll metabolism	38.89	7 of 18
66794	sulfate reduction	38.46	5 of 13
66794	carnitine metabolism	37.5	3 of 8
66794	ascorbate metabolism	36.36	8 of 22
66794	selenocysteine biosynthesis	33.33	2 of 6
66794	arachidonic acid metabolism	33.33	6 of 18
66794	sphingosine metabolism	33.33	2 of 6
66794	(5R)-carbapenem carboxylate biosynthesis	33.33	1 of 3
66794	sulfoquinovose degradation	33.33	1 of 3
66794	mevalonate metabolism	28.57	2 of 7
66794	degradation of sugar acids	28	7 of 25
66794	dolichyl-diphosphooligosaccharide biosynthesis	27.27	3 of 11

Isolation source categories

Isolation

Risk assessment

Genome sequences

@ref	Description	Assembly level	IMG accession	NCBI tax ID	Score
66792	Streptomyces netropsis NRRL 2820	complete	2563366704	55404	36.21

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20218	Streptomyces netropsis gene for 16S rRNA, partial sequence, strain: NBRC 12769	AB249911	1449		55404
20218	Streptomyces netropsis strain DSM 40093 16S ribosomal RNA gene, partial sequence	GU383218	779		55404
124043	Streptomyces netropsis gene for 16S ribosomal RNA, partial sequence, strain: JCM 4307.	D44049	120		55404

Literature

Topic	Title	Authors	Journal	DOI	Year
	Safety evaluation of the food enzyme phospholipase D from the non-genetically modified Streptomyces netropsis strain DSM 40093.	EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Fernandez-Fraguas C, Aguilera J, Andryszkiewicz M, Cavanna D, Liu Y.	EFSA J	10.2903/j.efsa.2025.9669	2025
	Update of the list of QPS-recommended biological agents intentionally added to food or feed as notified to EFSA 6: suitability of taxonomic units notified to EFSA until March 2017.	EFSA Panel on Biological Hazards (BIOHAZ), Ricci A, Allende A, Bolton D, Chemaly M, Davies R, Girones R, Koutsoumanis K, Lindqvist R, Norrung B, Robertson L, Ru G, Fernandez Escamez PS, Sanaa M, Simmons M, Skandamis P, Snary E, Speybroeck N, Ter Kuile B, Threlfall J, Wahlstrom H, Cocconcelli PS, Peixe L, Maradona MP, Querol A, Suarez JE, Sundh I, Vlak J, Correia S, Herman L.	EFSA J	10.2903/j.efsa.2017.4884	2017
Metabolism	Cloning of the netropsin resistance genes from Streptomyces flavopersicus NRRL 2820.	Stumpp T, Himbert S, Altenbuchner J	J Basic Microbiol	10.1002/jobm.200410529	2005
Metabolism	Enzymatic synthesis of aminoglycoside antibiotics: novel adenosylmethionine:2-deoxystreptamine N-methyltransferase activities in hygromycin B- and spectinomycin-producing Streptomyces spp. and uses of the methylated products.	Walker JB	Appl Environ Microbiol	10.1128/AEM.68.5.2404-2410.2002	2002
Metabolism	Enzymatic synthesis of aminocyclitol moieties of aminoglycoside antibiotics from inositol by Streptomyces spp.: detection of glutamine-aminocyclitol aminotransferase and diaminocyclitol aminotransferase activities in a spectinomycin producer.	Walker JB	J Bacteriol	10.1128/jb.177.3.818-822.1995	1995