Streptomyces lavendulae subsp. lavendulae (DSM 40069, ATCC 14158, ATCC 19777)

Cell morphology

Multimedia

• @ref:	9267
  multimedia content:	DSM_40069.jpg
  multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_40069.jpg
  caption:	Medium 65 28°C
  intellectual property rights:	© Leibniz-Institut DSMZ
  manual_annotation:	1

Culture medium

@ref	Name	Growth	Medium link	Composition
9267	ISP 5 MEDIUM (DSMZ Medium 993)		Medium recipe at MediaDive	Name: ISP 5 MEDIUM (DSMZ Medium 993) Composition: Agar 20.0 g/l Glycerol 10.0 g/l K2HPO4 1.0 g/l L-Asparagine 1.0 g/l FeSO4 x 7 H2O 0.001 g/l MnCl2 x 4 H2O 0.001 g/l ZnSO4 x 7 H2O 0.001 g/l Distilled water
9267	STARCH - MINERAL SALT - AGAR (STMS) (DSMZ Medium 252)		Medium recipe at MediaDive	Name: STARCH - MINERAL SALT - AGAR (STMS) (DSMZ Medium 252) Composition: Agar 20.0 g/l Starch 10.0 g/l (NH4)2SO4 2.0 g/l CaCO3 2.0 g/l K2HPO4 1.0 g/l MgSO4 x 7 H2O 1.0 g/l NaCl 1.0 g/l FeSO4 x 7 H2O 0.001 g/l MnCl2 x 4 H2O 0.001 g/l ZnSO4 x 7 H2O 0.001 g/l Distilled water
9267	ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84)		Medium recipe at MediaDive	Name: ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84) Composition: Agar 20.0 g/l Rolled oats 20.0 g/l ZnSO4 x 7 H2O 0.001 g/l MnCl2 x 4 H2O 0.001 g/l FeSO4 x 7 H2O 0.001 g/l Distilled water
9267	GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)		Medium recipe at MediaDive	Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 20.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water

Culture temp

Oxygen tolerance

Spore formation

Compound production

Observation

Metabolite production

@ref	Chebi-ID	Metabolite	Production
67770	26789 ChEBI	streptothricin

Isolation source categories

Isolation

Risk assessment

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	Streptomyces lavendulae lavendulae NBRC 12789	complete			2582581651	58340	96.07
67770	ASM71815v1 assembly for Streptomyces lavendulae subsp. lavendulae NRRL B-2774	contig	GCA_000718155	58340.12	2862351378	58340	7.5
66792	ASM131352v1 assembly for Streptomyces lavendulae subsp. lavendulae JCM 4055	contig	GCA_001313525	1303691.7	2734481950	1303691

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20218	Streptomyces sp. 14 16S ribosomal RNA gene, partial sequence	DQ304486	1154		361319
20218	Streptomyces lavendulae partial 16S rRNA	X53173	1329		1914
20218	Streptomyces lavendulae DNA for 16S rRNA, strain IFO 12343	D85111	1514		1914
20218	Streptomyces lavendulae DNA for 16S rRNA, strain IFO 12789	D85116	1514		1914
20218	Streptomyces lavendulae subsp. lavendulae 16S-23S ribosomal RNA gene spacer, partial sequence	U93347	280		58340
20218	Streptomyces lavendulae subsp. lavendulae gene for 16S ribosomal RNA, partial sequence, strain: JCM 4589	D44250	121		58340
20218	Streptomyces lavendulae subsp. lavendulae gene for 16S ribosomal RNA, partial sequence, strain: JCM 4664	D44293	120		58340
20218	Streptomyces lavendulae subsp. lavendulae gene for 16S rRNA, partial sequence, strain: NBRC 12789	AB184146	1435		58340
20218	Streptomyces lavendulae subsp. lavendulae gene for 16S rRNA, partial sequence, strain: NBRC 12903	AB249971	1457		58340
20218	Streptomyces lavendulae strain NRRL B-1230 16S ribosomal RNA gene, partial sequence	HQ426713	1530		1914
124043	Streptomyces lavendulae subsp. lavendulae ISP 5069 gene for 16S rRNA, partial sequence.	LC600146	1446		58340

GC content

Predictions

Literature

Topic	Title	Authors	Journal	DOI	Year
Metabolism	Proteolytic Processing, Maturation, and Unique Synteny of the Streptomyces Hemagglutinin SHA.	Fujita-Yamaguchi Y, Muramatsu H, Tapia A, Bagramyan K, Desai M, Takehana Y, Igarashi M, Yamaguchi Y, Kalkum M.	Microbiol Spectr	10.1128/spectrum.00766-21	2021
Metabolism	Mass spectrometric revival of an l-rhamnose- and d-galactose-specific lectin from a lost strain of Streptomyces.	Fujita-Yamaguchi Y, Bagramyan K, Yamaguchi Y, Ikeda A, Dohmae N, Hong TB, Kalkum M.	J Biol Chem	10.1074/jbc.m117.812719	2018
Metabolism	Streptothricin biosynthesis is catalyzed by enzymes related to nonribosomal peptide bond formation.	Fernandez-Moreno MA, Vallin C, Malpartida F.	J Bacteriol	10.1128/jb.179.22.6929-6936.1997	1997
	Steroids. 159. Antimicrobial properties of 21,21-dimethoxy progesterone and other progesterone analogues.	CASAS-CAMPILLO C, BALANDRANO D, GALARZA A.	J Bacteriol	10.1128/jb.81.3.366-375.1961	1961
	The bla gene of the cephamycin cluster of Streptomyces clavuligerus encodes a class A beta-lactamase of low enzymatic activity.	Perez-Llarena F, Martin JF, Galleni M, Coque JJ, Fuente JL, Frere JM, Liras P.	J Bacteriol	10.1128/jb.179.19.6035-6040.1997	1997
	Compilation of small ribosomal subunit RNA structures.	Neefs JM, Van de Peer Y, De Rijk P, Chapelle S, De Wachter R.	Nucleic Acids Res	10.1093/nar/21.13.3025	1993
Metabolism	Incorporation of carboxyl and methyl carbon-13 labeled acetates into racemomycin A by Streptomyces lavendulae ISP 5069.	Sawada Y, Kawakami S, Taniyama H, Inamori Y.	J Antibiot (Tokyo)	10.7164/antibiotics.30.630	1977
	Diversity and function of culturable actinobacteria in the root-associated of Salvia miltiorrhiza Bunge.	Wu YR, Li CB, Wu YH, Li L, Li B, Li WB, Ma BJ, Yan ZY.	PeerJ	10.7717/peerj.11749	2021
	Streptomyces lavendulae and Streptomyces venezuelae.	SANCHEZ-MARROQUIN A.	J Bacteriol	10.1128/jb.75.4.383-389.1958	1958
	Algicidal activity of a novel actinomycete strain, Streptomyces lavendulae, against the toxic cyanobacterium Anabaena lutea.	Butsat W, Somdee T, Somdee T.	Environ Sci Pollut Res Int	10.1007/s11356-025-36091-2	2025
	Copper inactivates DcsB by oxidizing the metal ligand Cys86 to sulfinic acid.	Oda K, Komaguchi K, Matoba Y.	FEBS J	10.1111/febs.17325	2024
	Evaluation of Collagenase Activity from Crab Hepatopancreas in Different Model Systems.	Plekhova NG, Chernenko IN, Korolev DV, Kozlovskaya EP, Stepanyugina AK, Shevchenko OV, Dmitrenok PS, Shumatov VB.	Bull Exp Biol Med	10.1007/s10517-024-06046-7	2024
	Identification and expression of key genes related to 1-deoxynojirimycin biosynthesis in Streptomyces lavendulae	Xin X, Jiang X, Niu B, Zhang M, Xu X, Zhang R, Li H, Gui Z.	Electron J Biotechnol		2023
	Streptothricin-F Inhibition of FtsZ Function: A Promising Approach for Controlling Pseudomonas syringae pv. actinidiae.	Wang H, Mi Q, Mao Y, Tan Y, Yang M, Liu W, Wang N, Tian X, Huang L.	J Agric Food Chem	10.1021/acs.jafc.3c08474	2024
	A new approach to osteoarthritis: gut microbiota.	Aydin M, Avci GA, Yilmaz UI, Avci E.	Rev Assoc Med Bras (1992)	10.1590/1806-9282.20241528	2025
	Identification of a critical gene involved in the biosynthesis of the polyene macrolide lavencidin in Streptomyces lavendulae FRI-5 using the Target-AID (activation-induced cytidine deaminase) base editing technology.	Otsuka R, Sato Y, Okano K, Okamura E, Tomita H, Honda K, Kitani S.	Appl Environ Microbiol	10.1128/aem.00975-24	2025
	Single cell mutant selection for metabolic engineering of actinomycetes.	Akhgari A, Baral B, Koroleva A, Siitonen V, Fewer DP, Melancon CE, Rahkila J, Metsa-Ketela M.	Metab Eng	10.1016/j.ymben.2022.07.002	2022
Metabolism	Lavencidin, a polyene macrolide antibiotic from Streptomyces lavendulae FRI-5.	Yoshioka T, Igarashi Y, Namba T, Ueda S, Pait IGU, Nihira T, Kitani S.	J Antibiot (Tokyo)	10.1038/s41429-020-00404-z	2021
	O-methyltransferase CbzMT catalyzes iterative 3,4-dimethylations for carbazomycin biosynthesis.	Lin B, Zhang D, Wang J, Qiao Y, Wang J, Deng Z, Kong L, You D.	Eng Microbiol	10.1016/j.engmic.2024.100150	2024
	Enzymatic synthesis of mono- and trifluorinated alanine enantiomers expands the scope of fluorine biocatalysis.	Nieto-Dominguez M, Sako A, Enemark-Rasmussen K, Gotfredsen CH, Rago D, Nikel PI.	Commun Chem	10.1038/s42004-024-01188-1	2024
	Biosurfactant Production by Bacillus amyloliquefaciens C11 and Streptomyces lavendulae C27 Isolated from a Biopurification System for Environmental Applications.	Diez MC, Llafquen C, Fincheira P, Lamilla C, Briceno G, Schalchli H.	Microorganisms	10.3390/microorganisms10101892	2022
Metabolism	Establishing Conserved Biosynthetic Gene Clusters of the Phylum Myxococcota	Pokharel S, Shehata N, Ahearne A, Knehans T, Bailey C, Boudreau P, Stevens D.	bioRxiv		2025
Genetics	Unveiling the hidden allies of industrial chicory-a metagenomic exploration of rhizosphere microbiota and their impact on productivity and plant health.	Leclercq L, Debarre S, Lloret E, Taminiau B, Daube G, Rambaud C, Drider D, Siah A, Desprez B, Hilbert JL, Lucau-Danila A.	Front Microbiol	10.3389/fmicb.2025.1509094	2025
	Chemo-enzymatic total synthesis: current approaches toward the integration of chemical and enzymatic transformations.	Tanifuji R, Oguri H.	Beilstein J Org Chem	10.3762/bjoc.20.151	2024
Metabolism	Cell-Free Synthesis of Natural Compounds from Genomic DNA of Biosynthetic Gene Clusters.	Siebels I, Nowak S, Heil CS, Tufar P, Cortina NS, Bode HB, Grininger M.	ACS Synth Biol	10.1021/acssynbio.0c00186	2020
	A lectin produced by a Streptomyces species targets mammalian pancreatic acinar cells in mice and humans.	Quijano JC, Natsuyama H, Tapia A, Bagramyan K, Ortiz JA, Mares J, Kalkum M, Fujita-Yamaguchi Y, Ku HT.	Sci Rep	10.1038/s41598-024-80889-y	2025
Proteome	Development and application of an LC-MS/MS method for quantification of fosmidomycin in human and rat plasma.	Pfaffendorf C, Sackmann KD, Mischlinger J, Dejon-Agobe JC, Maiga-Ascofare O, Ahenkan E, Adegnika AA, Ramharter M, Uhl P, Fricker G, Wicha SG.	Malar J	10.1186/s12936-025-05489-1	2025
	Coupling of cyclo-l-Trp-l-Trp with Hypoxanthine Increases the Structure Diversity of Guanitrypmycins.	Yu H, Xie X, Li SM.	Org Lett	10.1021/acs.orglett.9b03491	2019
Metabolism	Isolation of depsipeptides and optimization for enhanced production of valinomycin from the North-Western Himalayan cold desert strain Streptomyces lavendulae.	Singh VP, Sharma R, Sharma V, Raina C, Kapoor KK, Kumar A, Chaubey A, Singh D, Vishwakarma RA.	J Antibiot (Tokyo)	10.1038/s41429-019-0183-y	2019
	Improving the bacillomycin L production in Bacillus amyloliquefaciens by atmospheric and room-temperature plasma combined with Box-Behnken design.	Zhang A, Yang B, Ma Y, Li R, Zhou Z, Luo C, Zhang Y, Zhang Y, Dan Y, Sun Q.	Microb Cell Fact	10.1186/s12934-025-02774-1	2025
	Targeting antimalarial metabolites from the actinomycetes associated with the Red Sea sponge Callyspongia siphonella using a metabolomic method.	Gamaleldin NM, Bahr HS, Millan-Aguinaga N, Danesh M, Othman EM, Dandekar T, Hassan HM, Abdelmohsen UR.	BMC Microbiol	10.1186/s12866-023-03094-3	2023
	Programmed assembly of long DNA synthons: design, mechanism, and online monitoring.	Shchur VV, Burankova YP, Shapira MA, Klevzhits DV, Usanov SA, Yantsevich AV.	Appl Microbiol Biotechnol	10.1007/s00253-019-10099-4	2019
	Structural and mechanistic insights into KslB, a bacterial Pictet-Spenglerase in kitasetaline biosynthesis.	Kim W, Zheng Z, Kim K, Lee YH, Liu HW, Zhang YJ.	RSC Chem Biol	10.1039/d5cb00070j	2025
	Control of Cucumber Powdery Mildew Using Resistant Cultivars and Organic Agricultural Materials.	Kim MJ, Kim YK, Park SH, Park JH, Hong SJ, Shim CK.	J Microbiol Biotechnol	10.4014/jmb.2409.09030	2024
	A Multi-omics Approach Reveals the Effects of Bio- and Chemical- Pesticides on Rice Yield and Quality under Disease Stress.	Lu C, Yue Y, Liu B, Jiang Y, Li Z, Latif MZ, Zhang X, Chen D, Dai L, Kong L, Du Q, Yin Z, Li Y, Dong H, Ding X.	Rice (N Y)	10.1186/s12284-025-00822-3	2025
Metabolism	Discovery of a new diol-containing polyketide by heterologous expression of a silent biosynthetic gene cluster from Streptomyces lavendulae FRI-5.	Pait IGU, Kitani S, Roslan FW, Ulanova D, Arai M, Ikeda H, Nihira T.	J Ind Microbiol Biotechnol	10.1007/s10295-017-1997-x	2018
	Revelation and cloning of valinomycin synthetase genes in Streptomyces lavendulae ACR-DA1 and their expression analysis under different fermentation and elicitation conditions.	Sharma R, Jamwal V, Singh VP, Wazir P, Awasthi P, Singh D, Vishwakarma RA, Gandhi SG, Chaubey A.	J Biotechnol	10.1016/j.jbiotec.2017.05.008	2017
	Control of sweet potato Fusarium wilt and black rot by endophytic Bacillus velezensis with improved lipopeptide production.	Lee JG, Ji JH, Ryu S, Park JW, Paul NC, Park S, Im S, Han GH, Sang H.	BMC Microbiol	10.1186/s12866-025-04334-4	2025
Metabolism	Identification and characterization of lbpA, an indigoidine biosynthetic gene in the gamma-butyrolactone signaling system of Streptomyces lavendulae FRI-5.	Pait IGU, Kitani S, Kurniawan YN, Asa M, Iwai T, Ikeda H, Nihira T.	J Biosci Bioeng	10.1016/j.jbiosc.2017.04.020	2017
	Complete Genome Sequence of Streptomyces lavendulae subsp. lavendulae CCM 3239 (Formerly "Streptomyces aureofaciens CCM 3239"), a Producer of the Angucycline-Type Antibiotic Auricin.	Busche T, Novakova R, Al'Dilaimi A, Homerova D, Feckova L, Rezuchova B, Mingyar E, Csolleiova D, Bekeova C, Winkler A, Sevcikova B, Kalinowski J, Kormanec J, Ruckert C.	Genome Announc	10.1128/genomea.00103-18	2018
	Dinoflagellate Phosphopantetheinyl Transferase (PPTase) and Thiolation Domain Interactions Characterized Using a Modified Indigoidine Synthesizing Reporter.	Williams E, Bachvaroff T, Place A.	Microorganisms	10.3390/microorganisms10040687	2022
Metabolism	Identification and characterization of a new agar-degrading strain with the novel properties of saccharides inhibition and nitrogen fixation.	Wu H, Chen G, Bian Y, Zeng W, Sun B, Liang Z.	J Microbiol	10.1007/s12275-017-6464-x	2017
	Insights into the Activities and Usefulness of Deoxynojirimycin and Morus alba: A Comprehensive Review	Tricase A, Cavalluzzi M, Catalano A, De Bellis M, De Palma A, Basile G, Sinicropi M, Lentini G.	Molecules		2025
Transcriptome	Antifungal efficacy and mechanisms of Bacillus licheniformis BL06 against Ceratocystis fimbriata.	Gao F, Yang D, Chen J, Zhou X, Zhang C, Ma J, Tang W, Liang Z, Wu Y, Liu H, Sun H.	Front Plant Sci	10.3389/fpls.2025.1535296	2025
Genetics	Whole genomes of deep-sea sponge-associated bacteria exhibit high novel natural product potential.	Hesketh-Best PJ, January GG, Koch MJ, Warburton PJ, Howell KL, Upton M.	FEMS Microbes	10.1093/femsmc/xtad005	2023
	Optimization of Nutrient and Fermentation Parameters for Antifungal Activity by Streptomyces lavendulae Xjy and Its Biocontrol Efficacies against Fulvia fulva and Botryosphaeria dothidea	Gao X, He Q, Jiang Y, Huang L.	Journal of phytopathology.		2016
	(S)-3-aminopiperidine-2,6-dione is a biosynthetic intermediate of microbial blue pigment indigoidine.	Zhang Z, Li P, Wang M, Zhang Y, Wu B, Tao Y, Pan G, Chen Y.	mLife	10.1002/mlf2.12023	2022
Metabolism	Discovering potential Streptomyces hormone producers by using disruptants of essential biosynthetic genes as indicator strains.	Thao NB, Kitani S, Nitta H, Tomioka T, Nihira T.	J Antibiot (Tokyo)	10.1038/ja.2017.85	2017
	Structural and functional investigation of DinG containing a 3'-5' exonuclease domain.	Gao T, Hao W, Gao J, Sun Y, Sun Y, Yang J, Cheng K.	mBio	10.1128/mbio.00884-25	2025
Phylogeny	Production of the antimalarial drug precursor amorphadiene by microbial terpene synthase-like from the moss Sanionia uncinata.	Kim H, Lee Y, Yu J, Park JY, Lee J, Kim SG, Hyun Y.	Planta	10.1007/s00425-024-04558-0	2024
	Identification of Rhizospheric Actinomycete Streptomyces lavendulae SPS-33 and the Inhibitory Effect of its Volatile Organic Compounds against Ceratocystis Fimbriata in Postharvest Sweet Potato (Ipomoea Batatas (L.) Lam.).	Li X, Li B, Cai S, Zhang Y, Xu M, Zhang C, Yuan B, Xing K, Qin S.	Microorganisms	10.3390/microorganisms8030319	2020
Enzymology	Characterization and overproduction of cell-associated cholesterol oxidase ChoD from Streptomyces lavendulae YAKB-15.	Yamada K, Koroleva A, Laughlin M, Oksanen N, Akhgari A, Safronova V, Yakovleva E, Kolodyaznaya V, Buldakova T, Metsa-Ketela M.	Sci Rep	10.1038/s41598-019-48132-1	2019
Metabolism	Regulation of production of the blue pigment indigoidine by the pseudo gamma-butyrolactone receptor FarR2 in Streptomyces lavendulae FRI-5.	Kurniawan YN, Kitani S, Iida A, Maeda A, Lycklama a Nijeholt J, Lee YJ, Nihira T.	J Biosci Bioeng	10.1016/j.jbiosc.2015.08.013	2016
	[Genome-wide prediction and analysis of the secretory proteins and ORFs signal peptide of ginkgo endophyte KM-1-2]	Lu W, Liu C, Huang L, Yan X.	Wei Sheng Wu Xue Bao		2017
	Effects of actinomycetes on the growth, antioxidant and genes expression in Fritillaria taipaiensis P. Y. li.	Kong X, Han L, Yang L, Shi Z, Lang J, Ye M, Xiao B, Chen X, Zhou N.	Heliyon	10.1016/j.heliyon.2024.e34846	2024
	Investigating the initial steps of auricin biosynthesis using synthetic biology.	Csolleiova D, Javorova R, Novakova R, Feckova L, Matulova M, Opaterny F, Rezuchova B, Sevcikova B, Kormanec J.	AMB Express	10.1186/s13568-023-01591-2	2023
Metabolism	The structural and mutational analyses of O-ureido-L-serine synthase necessary for D-cycloserine biosynthesis.	Uda N, Matoba Y, Oda K, Kumagai T, Sugiyama M.	FEBS J	10.1111/febs.13386	2015
Pathogenicity	A Comparison of Dinoflagellate Thiolation Domain Binding Proteins Using In Vitro and Molecular Methods.	Williams E, Bachvaroff T, Place A.	Mar Drugs	10.3390/md20090581	2022
Metabolism	Differential contributions of two SARP family regulatory genes to indigoidine biosynthesis in Streptomyces lavendulae FRI-5.	Kurniawan YN, Kitani S, Maeda A, Nihira T.	Appl Microbiol Biotechnol	10.1007/s00253-014-5988-9	2014
	Structural-Based Virtual Screening of FDA-Approved Drugs Repository for NSP16 Inhibitors, Essential for SARS-COV-2 Invasion Into Host Cells: Elucidation From MM/PBSA Calculation.	Kumar S, Singh H, Prajapat M, Sarma P, Bhattacharyya A, Kaur H, Kaur G, Shekhar N, Kaushal K, Kumari K, Bansal S, Mahendiratta S, Chauhan A, Singh A, Soloman Singh R, Sharma S, Thota P, Avti P, Prakash A, Kuhad A, Medhi B.	Bioinform Biol Insights	10.1177/11779322231171777	2023
Enzymology	Unveiling aminopeptidase P from Streptomyces lavendulae: molecular cloning, expression and biochemical characterization.	Nandan AS, Nampoothiri KM.	Enzyme Microb Technol	10.1016/j.enzmictec.2013.11.003	2014
Metabolism	A Novel Strategy to Regulate 1-Deoxynojirimycin Production Based on Its Biosynthetic Pathway in Streptomyces lavendulae.	Wu H, Guo Y, Chen L, Chen G, Liang Z.	Front Microbiol	10.3389/fmicb.2019.01968	2019
Metabolism	A Structural Analysis of the Angucycline-Like Antibiotic Auricin from Streptomyces lavendulae Subsp. Lavendulae CCM 3239 Revealed Its High Similarity to Griseusins.	Matulova M, Feckova L, Novakova R, Mingyar E, Csolleiova D, Zduriencikova M, Sedlak J, Patoprsty V, Sasinkova V, Uhliarikova I, Sevcikova B, Rezuchova B, Homerova D, Kormanec J.	Antibiotics (Basel)	10.3390/antibiotics8030102	2019
	Systematic Evaluation of Biodegradation of Azo Dyes by Microorganisms: Efficient Species, Physicochemical Factors, and Enzymatic Systems	Carrascal-Hernandez D, Orozco-Beltran E, Insuasty D, Marquez E, Grande-Tovar C.	Int J Mol Sci		2025
Metabolism	Histidine residues at the copper-binding site in human tyrosinase are essential for its catalytic activities.	Noh H, Lee SJ, Jo HJ, Choi HW, Hong S, Kong KH.	J Enzyme Inhib Med Chem	10.1080/14756366.2020.1740691	2020
Transcriptome	Inhibitory Properties of Cinnamon Bark Oil against Postharvest Pathogen Penicillium digitatum In Vitro.	Zhou T, Pan J, Wang J, Yu Q, Zhang P, Lai T.	J Fungi (Basel)	10.3390/jof10040249	2024
	Optimization of the Fermentation Conditions of Metarhizium robertsii and Its Biological Control of Wolfberry Root Rot Disease.	He J, Zhang X, Wang Q, Li N, Ding D, Wang B.	Microorganisms	10.3390/microorganisms11102380	2023
Genetics	Whole Genome Sequencing and Metabolomic Study of Cave Streptomyces Isolates ICC1 and ICC4.	Gosse JT, Ghosh S, Sproule A, Overy D, Cheeptham N, Boddy CN.	Front Microbiol	10.3389/fmicb.2019.01020	2019
	Luobuma Leaf Spot Disease Caused by Alternaria tenuissima in China.	Lan Y, Yan Z, Duan T.	J Fungi (Basel)	10.3390/jof9111062	2023
	Screening and Identification of a Streptomyces Strain with Quorum-Sensing Inhibitory Activity and Effect of the Crude Extracts on Virulence Factors of Pseudomonas aeruginosa.	Zhang Z, Sun Y, Yi Y, Bai X, Zhu L, Zhu J, Gu M, Zhu Y, Jiang L.	Microorganisms	10.3390/microorganisms11082079	2023
Enzymology	Dihydrofolate reductase-like protein inactivates hemiaminal pharmacophore for self-resistance in safracin biosynthesis.	Shao N, Ma X, Zhang YY, Yang D, Ma M, Tang GL.	Acta Pharm Sin B	10.1016/j.apsb.2022.10.005	2023
	Discovery of a New Antibiotic Demethoxytetronasin Using a Dual-Sided Agar Plate Assay (DAPA).	Lee JH, Ma R, Nguyen L, Khan S, Qader M, Mpofu E, Shetye G, Krull NK, Augustinovic M, Omarsdottir S, Cho S, Franzblau SG, Murphy BT.	ACS Infect Dis	10.1021/acsinfecdis.3c00171	2023
	Proteomics fingerprinting reveals importance of iron and oxidative stress in Streptomyces scabies-Solanum tuberosum interactions.	Giroux L, Isayenka I, Lerat S, Beaudoin N, Beaulieu C.	Front Microbiol	10.3389/fmicb.2024.1466927	2024
Enzymology	Proline-specific extracellular aminopeptidase purified from Streptomyces lavendulae.	Nandan A, Pandey A, Nampoothiri KM.	Appl Biochem Biotechnol	10.1007/s12010-010-9103-0	2011
	Neural transcriptomic signature of chronic wasting disease in white-tailed deer.	O'Hara E, Herbst A, Kommadath A, Aiken JM, McKenzie D, Goodarzi N, Skinner P, Stothard P.	BMC Genomics	10.1186/s12864-022-08306-0	2022
Pathogenicity	Improving the simultaneous production of laccase and lignin peroxidase from Streptomyces lavendulae by medium optimization.	Jing D.	Bioresour Technol	10.1016/j.biortech.2010.04.087	2010
Metabolism	Development of fed-batch strategies for the production of streptavidin by Streptomyces avidinii based on power input and oxygen supply studies.	Muller JM, Risse JM, Jussen D, Flaschel E.	J Biotechnol	10.1016/j.jbiotec.2012.10.021	2013
	Apicoplast-Resident Processes: Exploiting the Chink in the Armour of Plasmodium falciparum Parasites.	Mamudu CO, Tebamifor ME, Sule MO, Dokunmu TM, Ogunlana OO, Iheagwam FN.	Adv Pharmacol Pharm Sci	10.1155/2024/9940468	2024
	Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides.	Hansen MH, Adamek M, Iftime D, Petras D, Schuseil F, Grond S, Stegmann E, Cryle MJ, Ziemert N.	Nat Commun	10.1038/s41467-023-43451-4	2023
	Process Development for 6-Aminopenicillanic Acid Production Using Lentikats-Encapsulated Escherichia coli Cells Expressing Penicillin V Acylase.	Sawant AM, Sunder AV, Vamkudoth KR, Ramasamy S, Pundle A.	ACS Omega	10.1021/acsomega.0c02813	2020
	Extending the Salinilactone Family.	Schlawis C, Harig T, Ehlers S, Guillen-Matus DG, Creamer KE, Jensen PR, Schulz S.	Chembiochem	10.1002/cbic.201900764	2020
Enzymology	Plant-Derived Cell-Free Biofactories for the Production of Secondary Metabolites.	Buntru M, Hahnengress N, Croon A, Schillberg S.	Front Plant Sci	10.3389/fpls.2021.794999	2021
Enzymology	A novel reporter system for bacterial and mammalian cells based on the non-ribosomal peptide indigoidine.	Muller M, Auslander S, Auslander D, Kemmer C, Fussenegger M.	Metab Eng	10.1016/j.ymben.2012.04.002	2012
	1-Deoxy-d-xylulose 5-phosphate reductoisomerase as target for anti Toxoplasma gondii agents: crystal structure, biochemical characterization and biological evaluation of inhibitors.	Mazzone F, Hoeppner A, Reiners J, Gertzen CGW, Applegate V, Abdullaziz MA, Gottstein J, Degrandi D, Wesemann M, Kurz T, Smits SHJ, Pfeffer K.	Biochem J	10.1042/bcj20240110	2024
Metabolism	Control of secondary metabolism by farX, which is involved in the gamma-butyrolactone biosynthesis of Streptomyces lavendulae FRI-5.	Kitani S, Doi M, Shimizu T, Maeda A, Nihira T.	Arch Microbiol	10.1007/s00203-010-0550-3	2010
Biotechnology	An Efficient Markerless Deletion System Suitable for the Industrial Strains of Streptomyces.	Dong J, Wei J, Li H, Zhao S, Guan W.	J Microbiol Biotechnol	10.4014/jmb.2106.06083	2021
	A rational multi-target combination strategy for synergistic improvement of non-ribosomal peptide production.	Yan H, Xin Z, Sang Z, Li X, Xie J, Wu J, Pang S, Wen Y, Wang W.	Nat Commun	10.1038/s41467-025-57073-5	2025
	Catalytic mechanism of DcsB: Arginase framework used for hydrolyzing its inhibitor.	Oda K, Sakaguchi T, Matoba Y.	Protein Sci	10.1002/pro.4338	2022
Metabolism	A functional screen for recovery of 4'-phosphopantetheinyl transferase and associated natural product biosynthesis genes from metagenome libraries.	Owen JG, Robins KJ, Parachin NS, Ackerley DF.	Environ Microbiol	10.1111/j.1462-2920.2012.02699.x	2012
	Current Trends in Clinical Trials of Prodrugs.	Boreski D, Schmid VF, Bosquesi PL, Dos Santos JL, Scarim CB, Reshetnikov V, Chin CM.	Pharmaceuticals (Basel)	10.3390/ph18020210	2025
Pathogenicity	Medium optimization by orthogonal array and response surface methodology for cholesterol oxidase production by Streptomyces lavendulae NCIM 2499.	Chauhan AK, Survase SA, Kishenkumar J, Annapure US.	J Gen Appl Microbiol	10.2323/jgam.55.171	2009
Metabolism	In vitro antimicrobial, antioxidant and cytotoxic properties of Streptomyces lavendulae strain SCA5.	Saravana Kumar P, Al-Dhabi NA, Duraipandiyan V, Balachandran C, Praveen Kumar P, Ignacimuthu S.	BMC Microbiol	10.1186/s12866-014-0291-6	2014
	Biocontrol activity of Bacillus halotolerans strain Pl7 against Botryosphaeria dothidea causing apple postharvest decay and potential mechanisms.	Yuan H, Yuan M, Shi B, Wang Z, Huang T, Zhu J, Hou H, Wang L, Tu H.	Front Microbiol	10.3389/fmicb.2022.1058167	2022
Metabolism	Fosmidomycin biosynthesis diverges from related phosphonate natural products.	Parkinson EI, Erb A, Eliot AC, Ju KS, Metcalf WW.	Nat Chem Biol	10.1038/s41589-019-0343-1	2019
	Stable isotope and chemical inhibition analyses suggested the existence of a non-mevalonate-like pathway in the yeast Yarrowia lipolytica.	Dissook S, Kuzuyama T, Nishimoto Y, Kitani S, Putri S, Fukusaki E.	Sci Rep	10.1038/s41598-021-85170-0	2021
	Regulation Mechanism of Nicotine Catabolism in Sphingomonas melonis TY by a Dual Role Transcriptional Regulator NdpR.	Wang H, Wang X, Tang Q, Wang L, Mei C, Shao Y, Xu Y, Lu Z, Zhong W.	Appl Environ Microbiol	10.1128/aem.00324-23	2023
Enzymology	Safety and Efficacy of s-MOX Regimen in Patients with Colorectal Cancer Who Developed Cardiotoxicity Following Fluoropyrimidine Administration: A Case Series.	Ehrlich MI, Kaley K, Smith M, Saif MW.	Arch Med Case Rep	10.33696/casereports.2.008	2020
Enzymology	Molecular cloning and functional analysis of minD gene from streptomyces lavendulae ATCC25233.	Nguyen TH, Kumagai T, Matoba Y, Suzaki T, Sugiyama M.	J Biosci Bioeng	10.1263/jbb.106.303	2008
Metabolism	A novel transglutaminase substrate from Streptomyces mobaraensis inhibiting papain-like cysteine proteases.	Sarafeddinov A, Arif A, Peters A, Fuchsbauer HL.	J Microbiol Biotechnol	10.4014/jmb.1012.12004	2011
	Bioactive Potential of Several Actinobacteria Isolated from Microbiologically Barely Explored Desert Habitat, Saudi Arabia.	Almuhayawi MS, Mohamed MSM, Abdel-Mawgoud M, Selim S, Al Jaouni SK, AbdElgawad H.	Biology (Basel)	10.3390/biology10030235	2021
Metabolism	Identification of cholesterol-assimilating actinomycetes strain and application of statistical modeling approaches for improvement of cholesterol oxidase production by Streptomyces anulatus strain NEAE-94.	El-Naggar NE, El-Shweihy NM.	BMC Microbiol	10.1186/s12866-020-01775-x	2020
Metabolism	Elevation of Fatty Acid Biosynthesis Metabolism Contributes to Zhongshengmycin Resistance in Xanthomonas oryzae.	Wang Q, Lin M, Shen P, Guan Y.	Antibiotics (Basel)	10.3390/antibiotics10101166	2021
	N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry.	Wang YL, Chang CY, Hsu NS, Lo IW, Lin KH, Chen CL, Chang CF, Wang ZC, Ogasawara Y, Dairi T, Maruyama C, Hamano Y, Li TL.	Nat Commun	10.1038/s41467-023-38218-w	2023
Pathogenicity	The Chemistry and Biology of Cyclophostin, the Cyclipostins and Related Compounds.	Spilling CD.	Molecules	10.3390/molecules24142579	2019
Metabolism	Identification of genes involved in the butyrolactone autoregulator cascade that modulates secondary metabolism in Streptomyces lavendulae FRI-5.	Kitani S, Iida A, Izumi TA, Maeda A, Yamada Y, Nihira T.	Gene	10.1016/j.gene.2008.07.043	2008
	Microorganism-Derived Molecules as Enzyme Inhibitors to Target Alzheimer's Diseases Pathways.	Nguyen TH, Wang SL, Nguyen VB.	Pharmaceuticals (Basel)	10.3390/ph16040580	2023
Enzymology	Heterocyclic Iminoquinones and Quinones from the National Cancer Institute (NCI, USA) COMPARE Analysis.	Haji N, Faizi M, Koutentis PA, Carty MP, Aldabbagh F.	Molecules	10.3390/molecules28135202	2023
Metabolism	Identification and characterization of an indigoidine-like gene for a blue pigment biosynthesis in Streptomyces aureofaciens CCM 3239.	Novakova R, Odnogova Z, Kutas P, Feckova L, Kormanec J.	Folia Microbiol (Praha)	10.1007/s12223-010-0018-5	2010
Metabolism	Production efficiency of the bacterial non-ribosomal peptide indigoidine relies on the respiratory metabolic state in S. cerevisiae.	Wehrs M, Prahl JP, Moon J, Li Y, Tanjore D, Keasling JD, Pray T, Mukhopadhyay A.	Microb Cell Fact	10.1186/s12934-018-1045-1	2018
Genetics	Discovery of Antimicrobial Phosphonopeptide Natural Products from Bacillus velezensis by Genome Mining.	Wilson J, Cui J, Nakao T, Kwok H, Zhang Y, Kayrouz CM, Pham TM, Roodhouse H, Ju KS.	Appl Environ Microbiol	10.1128/aem.00338-23	2023
	Heterologous production of the D-cycloserine intermediate O-acetyl-L-serine in a human type II pulmonary cell model.	Robbins L, Balaram A, Dejneka S, McMahon M, Najibi Z, Pawlowicz P, Conrad WH.	Sci Rep	10.1038/s41598-023-35632-4	2023
	An Unusual Oxidative Rearrangement Catalyzed by a Divergent Member of the 2-Oxoglutarate-Dependent Dioxygenase Superfamily during Biosynthesis of Dehydrofosmidomycin.	Parkinson EI, Lakkis HG, Alwali AA, Metcalf MEM, Modi R, Metcalf WW.	Angew Chem Int Ed Engl	10.1002/anie.202206173	2022
Metabolism	Differential regulation of undecylprodigiosin biosynthesis in the yeast-scavenging Streptomyces strain MBK6.	Bikash B, Vilja S, Mitchell L, Keith Y, Mikael I, Mikko MK, Jarmo N.	FEMS Microbiol Lett	10.1093/femsle/fnab044	2021
Pathogenicity	Identification and characterisation of a Streptomyces sp. isolate exhibiting activity against methicillin-resistant Staphylococcus aureus.	Higginbotham SJ, Murphy CD.	Microbiol Res	10.1016/j.micres.2008.12.004	2010
	Actinomycetes from the Red Sea Sponge Coscinoderma mathewsi: Isolation, Diversity, and Potential for Bioactive Compounds Discovery.	Shamikh YI, El Shamy AA, Gaber Y, Abdelmohsen UR, Madkour HA, Madkour HA, Horn H, Hassan HM, Elmaidomy AH, Alkhalifah DHM, Hozzein WN.	Microorganisms	10.3390/microorganisms8050783	2020
	A high-throughput colorimetric-based bioassay method for determination of fosmidomycin in plasma and urine and application for pharmacokinetic study.	Cheoymang A, Na-Bangchang K.	J Pharmacol Toxicol Methods	10.1016/j.vascn.2010.02.012	2010
Enzymology	Overexpression of penicillin V acylase from Streptomyces lavendulae and elucidation of its catalytic residues.	Torres-Bacete J, Hormigo D, Torres-Guzman R, Arroyo M, Castillon MP, Garcia L, Acebal C, de la Mata I.	Appl Environ Microbiol	10.1128/aem.02352-14	2015
	[Screen, identification and optimized fermentation condition of an actinomycete strain against pathogenic fungus Fulvia fulva].	Jiang Y, Huang LL, Chen CQ, Qiao HP, Kang ZS.	Wei Sheng Wu Xue Bao		2007
	Inhibition of DXR in the MEP pathway with lipophilic N-alkoxyaryl FR900098 analogs.	Bague D, Wang R, Hodge D, Mikati MO, Roma JS, Boshoff HI, Dailey AL, Girma M, Couch RD, Odom John AR, Dowd CS.	RSC Med Chem	10.1039/d3md00642e	2024
Metabolism	Analysis of a parallel branch in the mitomycin biosynthetic pathway involving the mitN-encoded aziridine N-methyltransferase.	Sitachitta N, Lopanik NB, Mao Y, Sherman DH.	J Biol Chem	10.1074/jbc.m702456200	2007
Pathogenicity	Inhibitory Activity of Plant Essential Oils against E. coli 1-Deoxy-d-xylulose-5-phosphate reductoisomerase.	Yan G, Zhu BR, Tian FL, Hui X, Li H, Li YM, Gao WY.	Molecules	10.3390/molecules24142518	2019
	Biosynthesis of 3-hydroxy-5-methyl-o-methyltyrosine in the saframycin/ safracin biosynthetic pathway.	Fu CY, Tang MC, Peng C, Li L, He YL, Liu W, Tang GL.	J Microbiol Biotechnol	10.4014/jmb.0808.484	2009
	Mechanism of Action of N-Acyl and N-Alkoxy Fosmidomycin Analogs: Mono- and Bisubstrate Inhibition of IspC from Plasmodium falciparum, a Causative Agent of Malaria.	Girma MB, Ball HS, Wang X, Brothers RC, Jackson ER, Meyers MJ, Dowd CS, Couch RD.	ACS Omega	10.1021/acsomega.1c01711	2021
Metabolism	A bacterial DNA repair pathway specific to a natural antibiotic.	Burby PE, Simmons LA.	Mol Microbiol	10.1111/mmi.14158	2019
Pathogenicity	3-Methylarginine from Pseudomonas syringae pv. syringae 22d/93 suppresses the bacterial blight caused by its close relative Pseudomonas syringae pv. glycinea.	Braun SD, Volksch B, Nuske J, Spiteller D.	Chembiochem	10.1002/cbic.200800080	2008
	A novel catalytic heme cofactor in SfmD with a single thioether bond and a bis-His ligand set revealed by a de novo crystal structural and spectroscopic study.	Shin I, Davis I, Nieves-Merced K, Wang Y, McHardy S, Liu A.	Chem Sci	10.1039/d0sc06369j	2021
Enzymology	Optimization of culture medium and conditions for penicillin acylase production by Streptomyces lavendulae ATCC 13664.	Torres-Bacete J, Arroyo M, Torres-Guzman R, De La Mata I, Acebal C, Castillon MP.	Appl Biochem Biotechnol	10.1385/abab:126:2:119	2005
	Diversity, mechanisms and beneficial features of phosphate-solubilizing Streptomyces in sustainable agriculture: A review.	Chouyia FE, Ventorino V, Pepe O.	Front Plant Sci	10.3389/fpls.2022.1035358	2022
	Characterizing the mucin-degrading capacity of the human gut microbiota.	Glover JS, Ticer TD, Engevik MA.	Sci Rep	10.1038/s41598-022-11819-z	2022
	Maize-soybean relay strip intercropping reshapes the rhizosphere bacterial community and recruits beneficial bacteria to suppress Fusarium root rot of soybean.	Chang X, Wei D, Zeng Y, Zhao X, Hu Y, Wu X, Song C, Gong G, Chen H, Yang C, Zhang M, Liu T, Chen W, Yang W.	Front Microbiol	10.3389/fmicb.2022.1009689	2022
	Genome sequence of Epibacterium ulvae strain DSM 24752T, an indigoidine-producing, macroalga-associated member of the marine Roseobacter group.	Breider S, Sehar S, Berger M, Thomas T, Brinkhoff T, Egan S.	Environ Microbiome	10.1186/s40793-019-0343-5	2019
Phylogeny	[Research on the classification of streptomyces strain ZG0429 and purification of streptavidin].	Zhang L, Liu CQ, Gao ZH, Cao Y, Bai G.	Wei Sheng Wu Xue Bao		2007
	Teaching an old 'doc' new tricks for algal biotechnology: Strategic filter use enables multi-scale fluorescent protein signal detection.	Gutierrez S, Wellman GB, Lauersen KJ.	Front Bioeng Biotechnol	10.3389/fbioe.2022.979607	2022
	Characterization of Streptomyces sp. KB1 and its cultural optimization for bioactive compounds production.	Lertcanawanichakul M, Sahabuddeen T.	PeerJ	10.7717/peerj.14909	2023
Enzymology	A thermostable laccase from Streptomyces lavendulae REN-7: purification, characterization, nucleotide sequence, and expression.	Suzuki T, Endo K, Ito M, Tsujibo H, Miyamoto K, Inamori Y.	Biosci Biotechnol Biochem	10.1271/bbb.67.2167	2003
Metabolism	Self-protection mechanism in D-cycloserine-producing Streptomyces lavendulae. Gene cloning, characterization, and kinetics of its alanine racemase and D-alanyl-D-alanine ligase, which are target enzymes of D-cycloserine.	Noda M, Kawahara Y, Ichikawa A, Matoba Y, Matsuo H, Lee DG, Kumagai T, Sugiyama M.	J Biol Chem	10.1074/jbc.m404603200	2004
Metabolism	In Bacillus subtilis, the SatA (Formerly YyaR) Acetyltransferase Detoxifies Streptothricin via Lysine Acetylation.	Burckhardt RM, Escalante-Semerena JC.	Appl Environ Microbiol	10.1128/aem.01590-17	2017
Metabolism	High-Level Heterologous Production of D-Cycloserine by Escherichia coli.	Kumagai T, Ozawa T, Tanimoto M, Noda M, Matoba Y, Sugiyama M.	Appl Environ Microbiol	10.1128/aem.02187-15	2015
	Hydroxyquinone O-methylation in mitomycin biosynthesis.	Gruschow S, Chang LC, Mao Y, Sherman DH.	J Am Chem Soc	10.1021/ja0700193	2007
Enzymology	Novel family of cholesterol esterases produced by actinomycetes bacteria.	Xiang H, Masuo S, Hoshino T, Takaya N.	Biochim Biophys Acta	10.1016/j.bbapap.2006.11.001	2007
	Salient features of the aza-Wacker cyclization reaction.	Thomas AA, Nagamalla S, Sathyamoorthi S.	Chem Sci	10.1039/d0sc02554b	2020
Enzymology	Fluostatins C-E, novel members of the fluostatin family produced by Streptomyces strain Acta 1383.	Baur S, Niehaus J, Karagouni AD, Katsifas EA, Chalkou K, Meintanis C, Jones AL, Goodfellow M, Ward AC, Beil W, Schneider K, Sussmuth RD, Fiedler HP.	J Antibiot (Tokyo)	10.1038/ja.2006.41	2006
	Cloning and characterization of a Streptomyces single module type non-ribosomal peptide synthetase catalyzing a blue pigment synthesis.	Takahashi H, Kumagai T, Kitani K, Mori M, Matoba Y, Sugiyama M.	J Biol Chem	10.1074/jbc.m611319200	2007
	Investigating and Optimizing the Lysate-Based Expression of Nonribosomal Peptide Synthetases Using a Reporter System.	Dinglasan JLN, Sword TT, Barker JW, Doktycz MJ, Bailey CB.	ACS Synth Biol	10.1021/acssynbio.2c00658	2023
Metabolism	Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions.	Eger E, Simon A, Sharma M, Yang S, Breukelaar WB, Grogan G, Houk KN, Kroutil W.	J Am Chem Soc	10.1021/jacs.9b08704	2020
Metabolism	DNA sequencing and transcriptional analysis of the kasugamycin biosynthetic gene cluster from Streptomyces kasugaensis M338-M1.	Ikeno S, Aoki D, Hamada M, Hori M, Tsuchiya KS.	J Antibiot (Tokyo)	10.1038/ja.2006.4	2006
Metabolism	Substrate specificity of penicillin acylase from Streptomyces lavendulae.	Torres-Guzman R, de la Mata I, Torres-Bacete J, Arroyo M, Castillon MP, Acebal C.	Biochem Biophys Res Commun	10.1006/bbrc.2002.6485	2002
Metabolism	Bioactivity-HiTES Unveils Cryptic Antibiotics Encoded in Actinomycete Bacteria.	Moon K, Xu F, Zhang C, Seyedsayamdost MR.	ACS Chem Biol	10.1021/acschembio.9b00049	2019
Metabolism	Improved 1-Deoxynojirimycin (DNJ) production in mulberry leaves fermented by microorganism.	Jiang YG, Wang CY, Jin C, Jia JQ, Guo X, Zhang GZ, Gui ZZ.	Braz J Microbiol	10.1590/s1517-83822014000200048	2014
	A four-protein metabolon assembled by a small peptide protein creates the pentacyclic carbonate ring of aldgamycins.	Wang Q, Tang X, Dai P, Wang C, Zhang W, Chen G, Hong K, Hu D, Gao H, Yao X.	Acta Pharm Sin B	10.1016/j.apsb.2020.07.015	2021
	The Amipurimycin and Miharamycin Biosynthetic Gene Clusters: Unraveling the Origins of 2-Aminopurinyl Peptidyl Nucleoside Antibiotics.	Romo AJ, Shiraishi T, Ikeuchi H, Lin GM, Geng Y, Lee YH, Liem PH, Ma T, Ogasawara Y, Shin-Ya K, Nishiyama M, Kuzuyama T, Liu HW.	J Am Chem Soc	10.1021/jacs.9b03021	2019
	Novel Bifunctional Acylase from Actinoplanes utahensis: A Versatile Enzyme to Synthesize Antimicrobial Compounds and Use in Quorum Quenching Processes.	Serrano-Aguirre L, Velasco-Bucheli R, Garcia-Alvarez B, Saborido A, Arroyo M, de la Mata I.	Antibiotics (Basel)	10.3390/antibiotics10080922	2021
	Targeted and high-throughput gene knockdown in diverse bacteria using synthetic sRNAs.	Cho JS, Yang D, Prabowo CPS, Ghiffary MR, Han T, Choi KR, Moon CW, Zhou H, Ryu JY, Kim HU, Lee SY.	Nat Commun	10.1038/s41467-023-38119-y	2023
Genetics	Bioactive Metabolites from Terrestrial and Marine Actinomycetes.	Ngamcharungchit C, Chaimusik N, Panbangred W, Euanorasetr J, Intra B.	Molecules	10.3390/molecules28155915	2023
	Degradation of chlorpyriphos and polyethylene by endosymbiotic bacteria from citrus mealybug.	Ibrahim S, Gupta RK, War AR, Hussain B, Kumar A, Sofi T, Noureldeen A, Darwish H.	Saudi J Biol Sci	10.1016/j.sjbs.2021.03.058	2021
Metabolism	[The carbohydrate-containing cell wall polymers of some species from the cluster "Streptomyces lavendulae"].	Shashkov AS, Kozlova IuI, Streshinskaia GM, Kosmachevskaia LN, Bueva OV, Evtushenko LI, Naumova IB.	Mikrobiologiia	10.1023/a:1010478009924	2001
Enzymology	Novel selection marker for mammalian cell transfection.	Baumann RP, Sherman DH, Sartorelli AC.	Biotechniques	10.2144/02325st03	2002
	Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein.	Martin TW, Dauter Z, Devedjiev Y, Sheffield P, Jelen F, He M, Sherman DH, Otlewski J, Derewenda ZS, Derewenda U.	Structure	10.1016/s0969-2126(02)00778-5	2002
Metabolism	Activation and stabilization of penicillin V acylase from streptomyces lavendulae in the presence of glycerol and glycols.	Arroyo M, Torres-Guzman R, de La Mata I, Castillon MP, Acebal C.	Biotechnol Prog	10.1021/bp000023h	2000
	Inhibitory effects of carbohydrates on cholesterol esterase biosynthesis in Streptomyces lavendulae H646-SY2.	Nishimura M, Inouye S.	J Biosci Bioeng	10.1016/s1389-1723(01)80042-6	2000
Metabolism	Functional and Structural Analysis of Phenazine O-Methyltransferase LaPhzM from Lysobacter antibioticus OH13 and One-Pot Enzymatic Synthesis of the Antibiotic Myxin.	Jiang J, Guiza Beltran D, Schacht A, Wright S, Zhang L, Du L.	ACS Chem Biol	10.1021/acschembio.8b00062	2018
Phylogeny	Streptomyces globosus DK15 and Streptomyces ederensis ST13 as new producers of factumycin and tetrangomycin antibiotics.	Charousova I, Medo J, Hleba L, Javorekova S.	Braz J Microbiol	10.1016/j.bjm.2017.12.007	2018
Enzymology	Enhanced production of penicillin V acylase from Streptomyces lavendulae.	Torres R, Ramon F, de la Mata I, Acebal C, Castillon MP.	Appl Microbiol Biotechnol	10.1007/s002530051618	1999
Enzymology	Crystallization and preliminary X-ray diffraction analysis of alanine racemase from Pseudomonas putida YZ-26.	Liu J, Feng L, Shi Y, Feng W.	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/s1744309112036974	2012
Metabolism	Molecular cloning and heterologous expression of a biosynthetic gene cluster for the antitubercular agent D-cycloserine produced by Streptomyces lavendulae.	Kumagai T, Koyama Y, Oda K, Noda M, Matoba Y, Sugiyama M.	Antimicrob Agents Chemother	10.1128/aac.01226-09	2010
Phylogeny	Efficient transformation procedure of a newly isolated Streptomyces sp. TN58 strain producing antibacterial activities.	Mellouli L, Karray-Rebai I, Sioud S, Ben Ameur-Mehdi R, Naili B, Bejar S.	Curr Microbiol	10.1007/s00284-004-4292-9	2004
Enzymology	Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.	Noda M, Matoba Y, Kumagai T, Sugiyama M.	J Biol Chem	10.1074/jbc.m404605200	2004
	Rapid and specific method for evaluating Streptomyces competitive dynamics in complex soil communities.	Schlatter DC, Samac DA, Tesfaye M, Kinkel LL.	Appl Environ Microbiol	10.1128/aem.02320-09	2010
Enzymology	Crystallization and preliminary X-ray study of a thermostable alanine racemase from Thermoanaerobacter tengcongensis MB4.	Dong H, Xu S, Lu X, He G, Zhao R, Chen S, Fu S, Ju J.	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/s1744309113011743	2013
	Distribution and functional analysis of the phosphopantetheinyl transferase superfamily in Actinomycetales microorganisms.	Kim JH, Komatsu M, Shin-Ya K, Omura S, Ikeda H.	Proc Natl Acad Sci U S A	10.1073/pnas.1800715115	2018
	Development of genetic tools for heterologous protein expression in a pentose-utilizing environmental isolate of Pseudomonas putida.	Gauttam R, Eng T, Zhao Z, Ul Ain Rana Q, Simmons BA, Yoshikuni Y, Mukhopadhyay A, Singer SW.	Microb Biotechnol	10.1111/1751-7915.14205	2023
	Regulation of Antibiotic Production by Signaling Molecules in Streptomyces.	Kong D, Wang X, Nie J, Niu G.	Front Microbiol	10.3389/fmicb.2019.02927	2019
	Determination of d-Cycloserine Impurities in Pharmaceutical Dosage Forms: Comparison of the International Pharmacopoeia HPLC-UV Method and the DOSY NMR Method.	Makuc D, Svab Z, Naumoska K, Plavec J, Casar Z.	Molecules	10.3390/molecules25071684	2020
Metabolism	Rhodosporidium toruloides - A potential red yeast chassis for lipids and beyond.	Wen Z, Zhang S, Odoh CK, Jin M, Zhao ZK.	FEMS Yeast Res	10.1093/femsyr/foaa038	2020
Phylogeny	The planctomycete Stieleria maiorica Mal15T employs stieleriacines to alter the species composition in marine biofilms.	Kallscheuer N, Jeske O, Sandargo B, Boedeker C, Wiegand S, Bartling P, Jogler M, Rohde M, Petersen J, Medema MH, Surup F, Jogler C.	Commun Biol	10.1038/s42003-020-0993-2	2020
	Identification of a novel structure-specific endonuclease AziN that contributes to the repair of azinomycin B-mediated DNA interstrand crosslinks.	Chen X, Sun Y, Wang S, Ying K, Xiao L, Liu K, Zuo X, He J.	Nucleic Acids Res	10.1093/nar/gkz1067	2020
Metabolism	Optimization of 6-aminopenicillanic acid (6-APA) production by using a new immobilized penicillin acylase.	Torres-Bacete J, Arroyo M, Torres-Guzman R, de La Mata I, Castillon MP, Acebal C.	Biotechnol Appl Biochem	10.1042/ba20000042	2000
Metabolism	Studies on the formation and incorporation of streptolidine in the biosynthesis of the peptidyl nucleoside antibiotic streptothricin F.	Jackson MD, Gould SJ, Zabriskie TM.	J Org Chem	10.1021/jo016182c	2002
Enzymology	Therapeutic and biotechnological applications of substrate specific microbial aminopeptidases.	Nandan A, Nampoothiri KM.	Appl Microbiol Biotechnol	10.1007/s00253-020-10641-9	2020
	Bilateral symmetry of linear streptomycete chromosomes.	Algora-Gallardo L, Schniete JK, Mark DR, Hunter IS, Herron PR.	Microb Genom	10.1099/mgen.0.000692	2021
Metabolism	Inducible synthesis of the mitomycin C resistance gene product (MCRA) from Streptomyces lavendulae.	August PR, Rahn JA, Flickinger MC, Sherman DH.	Gene	10.1016/0378-1119(96)00172-2	1996
	Quorum sensing interference by phenolic compounds - A matter of bacterial misunderstanding.	Lima EMF, Winans SC, Pinto UM.	Heliyon	10.1016/j.heliyon.2023.e17657	2023
	Prediction of penicillin V acylase stability in water-organic co-solvent monophasic systems as a function of solvent composition.	Arroyo M, Torres-Guzman R, de la Mata I, Castillon MP, Acebal C.	Enzyme Microb Technol	10.1016/s0141-0229(00)00183-6	2000
Metabolism	Functional Cross-Talk of MbtH-Like Proteins During Thaxtomin Biosynthesis in the Potato Common Scab Pathogen Streptomyces scabiei.	Li Y, Tahlan K, Bignell DRD.	Front Microbiol	10.3389/fmicb.2020.585456	2020
	Structural characterization of the mitomycin 7-O-methyltransferase.	Singh S, Chang A, Goff RD, Bingman CA, Gruschow S, Sherman DH, Phillips GN, Thorson JS.	Proteins	10.1002/prot.23040	2011
	Adaptive Enrichment of a Thermophilic Bacterial Isolate for Enhanced Enzymatic Activity.	Govil T, Saxena P, Samanta D, Singh SS, Kumar S, Salem DR, Sani RK.	Microorganisms	10.3390/microorganisms8060871	2020
	Isothiourea-catalysed enantioselective pyrrolizine synthesis: synthetic and computational studies.	Stark DG, Williamson P, Gayner ER, Musolino SF, Kerr RW, Taylor JE, Slawin AM, O'Riordan TJ, Macgregor SA, Smith AD.	Org Biomol Chem	10.1039/c6ob01557c	2016
Metabolism	Bioactivities of Halometabolites from Marine Actinobacteria.	Kasanah N, Triyanto T.	Biomolecules	10.3390/biom9060225	2019
Phylogeny	Identification of biosynthetic gene clusters from metagenomic libraries using PPTase complementation in a Streptomyces host.	Bitok JK, Lemetre C, Ternei MA, Brady SF.	FEMS Microbiol Lett	10.1093/femsle/fnx155	2017
	Investigation of the Autoregulator-Receptor System in the Pristinamycin Producer Streptomyces pristinaespiralis.	Handel F, Kulik A, Mast Y.	Front Microbiol	10.3389/fmicb.2020.580990	2020
Metabolism	Viability studies on actinomycetes.	Taddei A, Tremarias MM, Hartung de Capriles C.	Mycopathologia	10.1023/a:1006907815425	1998
	Cloning, nucleotide sequence and expression of a beta-lactamase gene from Streptomyces lavendulae.	Sendouda A, Urabe H, Ogawara H.	FEMS Microbiol Lett	10.1111/j.1574-6968.1993.tb06473.x	1993
Metabolism	Involvement of amfC in physiological and morphological development in Streptomyces coelicolor A3(2).	Yonekawa T, Ohnishi Y, Horinouchi S.	Microbiology (Reading)	10.1099/00221287-145-9-2273	1999
Metabolism	Interplay between siderophores and colibactin genotoxin biosynthetic pathways in Escherichia coli.	Martin P, Marcq I, Magistro G, Penary M, Garcie C, Payros D, Boury M, Olier M, Nougayrede JP, Audebert M, Chalut C, Schubert S, Oswald E.	PLoS Pathog	10.1371/journal.ppat.1003437	2013
	Biosynthesis of alpha-Glucosidase Inhibitors by a Newly Isolated Bacterium, Paenibacillus sp. TKU042 and Its Effect on Reducing Plasma Glucose in a Mouse Model.	Nguyen VB, Nguyen AD, Kuo YH, Wang SL.	Int J Mol Sci	10.3390/ijms18040700	2017
Genetics	The Genome Analysis of the Human Lung-Associated Streptomyces sp. TR1341 Revealed the Presence of Beneficial Genes for Opportunistic Colonization of Human Tissues.	Lara AC, Corretto E, Kotrbova L, Lorenc F, Petrickova K, Grabic R, Chronakova A.	Microorganisms	10.3390/microorganisms9081547	2021
Enzymology	Cloning, sequence and expression of the argG gene from Streptomyces lavendulae.	Ogawara H, Kasama H, Nashimoto K, Ohtsubo M, Higashi K, Urabe H.	Gene	10.1016/0378-1119(93)90751-n	1993
Genetics	Discovery of an Antibiotic-Related Small Protein of Biocontrol Strain Pseudomonas sp. Os17 by a Genome-Mining Strategy.	Takeuchi K, Tsuchiya W, Fujimoto Z, Yamada K, Someya N, Yamazaki T.	Front Microbiol	10.3389/fmicb.2020.605705	2020
Phylogeny	Isolation and Molecular Identification of Streptomyces spp. with Antibacterial Activity from Northwest of Iran.	Maleki H, Dehnad A, Hanifian S, Khani S.	Bioimpacts	10.5681/bi.2013.017	2013
	Horizontal gene transfer involved in the convergent evolution of the plasmid-encoded enantioselective 6-hydroxynicotine oxidases.	Schenk S, Decker K.	J Mol Evol	10.1007/pl00006456	1999
Metabolism	Heme protein and hydroxyarginase necessary for biosynthesis of D-cycloserine.	Kumagai T, Takagi K, Koyama Y, Matoba Y, Oda K, Noda M, Sugiyama M.	Antimicrob Agents Chemother	10.1128/aac.00614-12	2012
Enzymology	Expression, crystallization and preliminary crystallographic data analysis of PigF, an O-methyltransferase from the prodigiosin-synthetic pathway in Serratia.	Liu S, Ran T, Shen X, Xu L, Wang W, Xu D.	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/s1744309112024001	2012
	Leisingera sp. JC1, a Bacterial Isolate from Hawaiian Bobtail Squid Eggs, Produces Indigoidine and Differentially Inhibits Vibrios.	Gromek SM, Suria AM, Fullmer MS, Garcia JL, Gogarten JP, Nyholm SV, Balunas MJ.	Front Microbiol	10.3389/fmicb.2016.01342	2016
Enzymology	Structural insights into phosphopantetheinyl hydrolase PptH from Mycobacterium tuberculosis.	Mosior J, Bourland R, Soma S, Nathan C, Sacchettini J.	Protein Sci	10.1002/pro.3813	2020
Metabolism	Comparative Investigation into Formycin A and Pyrazofurin A Biosynthesis Reveals Branch Pathways for the Construction of C-Nucleoside Scaffolds.	Zhang M, Zhang P, Xu G, Zhou W, Gao Y, Gong R, Cai YS, Cong H, Deng Z, Price NPJ, Mao X, Chen W.	Appl Environ Microbiol	10.1128/aem.01971-19	2020
	Atomic resolution structure of EhpR: phenazine resistance in Enterobacter agglomerans Eh1087 follows principles of bleomycin/mitomycin C resistance in other bacteria.	Yu S, Vit A, Devenish S, Mahanty HK, Itzen A, Goody RS, Blankenfeldt W.	BMC Struct Biol	10.1186/1472-6807-11-33	2011
Enzymology	Characterization of the sat4 gene encoding a streptothricin acetyltransferase in Campylobacter coli BE/G4.	Jacob J, Evers S, Bischoff K, Carlier C, Courvalin P.	FEMS Microbiol Lett	10.1111/j.1574-6968.1994.tb07000.x	1994
Phylogeny	Application of the random amplified polymorphic DNA using the polymerase chain reaction for efficient elimination of duplicate strains in microbial screening. II. Actinomycetes.	Anzai Y, Okuda T, Watanabe J.	J Antibiot (Tokyo)	10.7164/antibiotics.47.183	1994
Metabolism	Protein tyrosine phosphorylation in streptomycetes.	Waters B, Vujaklija D, Gold MR, Davies J.	FEMS Microbiol Lett	10.1111/j.1574-6968.1994.tb07028.x	1994
Pathogenicity	Fosmidomycin, an inhibitor of isoprenoid synthesis, induces persistence in Chlamydia by inhibiting peptidoglycan assembly.	Slade JA, Brockett M, Singh R, Liechti GW, Maurelli AT.	PLoS Pathog	10.1371/journal.ppat.1008078	2019
	Validation of an HPLC-MS/MS and wipe procedure for mitomycin C contamination.	B'Hymer C, Connor T, Stinson D, Pretty J.	J Chromatogr Sci	10.1093/chromsci/bmu095	2015
Pathogenicity	Assessing the effectiveness of functional genetic screens for the identification of bioactive metabolites.	Penesyan A, Ballestriero F, Daim M, Kjelleberg S, Thomas T, Egan S.	Mar Drugs	10.3390/md11010040	2012
Phylogeny	A taxonomic review of the genera Kitasatosporia and Streptoverticillium by analysis of ribosomal protein AT-L30.	Ochi K, Hiranuma H.	Int J Syst Bacteriol	10.1099/00207713-44-2-285	1994
Enzymology	Bacterial ribonuclease: mutagenic effect in microbial test-systems.	Ilinskaya O, Ivanchenko OB, Karamova NS.	Mutagenesis	10.1093/mutage/10.3.165	1995
	Extracellular cholesterol oxidase production by Streptomyces aegyptia, in vitro anticancer activities against rhabdomyosarcoma, breast cancer cell-lines and in vivo apoptosis.	El-Naggar NE, Soliman HM, El-Shweihy NM.	Sci Rep	10.1038/s41598-018-20786-3	2018
	Recent Advances in Strategies for Activation and Discovery/Characterization of Cryptic Biosynthetic Gene Clusters in Streptomyces.	Nguyen CT, Dhakal D, Pham VTT, Nguyen HT, Sohng JK.	Microorganisms	10.3390/microorganisms8040616	2020
	Quorum Sensing versus Quenching Bacterial Isolates Obtained from MBR Plants Treating Leachates from Municipal Solid Waste.	Soler A, Arregui L, Arroyo M, Mendoza JA, Muras A, Alvarez C, Garcia-Vera C, Marquina D, Santos A, Serrano S.	Int J Environ Res Public Health	10.3390/ijerph15051019	2018
Metabolism	Complestatin, a potent anti-complement substance produced by Streptomyces lavendulae. I. Fermentation, isolation and biological characterization.	Kaneko I, Kamoshida K, Takahashi S.	J Antibiot (Tokyo)	10.7164/antibiotics.42.236	1989
Metabolism	Genome-scale metabolic rewiring improves titers rates and yields of the non-native product indigoidine at scale.	Banerjee D, Eng T, Lau AK, Sasaki Y, Wang B, Chen Y, Prahl JP, Singan VR, Herbert RA, Liu Y, Tanjore D, Petzold CJ, Keasling JD, Mukhopadhyay A.	Nat Commun	10.1038/s41467-020-19171-4	2020
	Potential risk of mitomycin C at high concentrations on peripheral nerve structure.	Sui T, Zhang J, Du S, Su C, Que J, Cao X.	Neural Regen Res	10.4103/1673-5374.131598	2014
Metabolism	Microbial and mammalian metabolism studies of the semisynthetic antimalarial, anhydrodihydroartemisinin.	Khalifa SI, Baker JK, Rogers RD, el-Feraly FS, Hufford CD.	Pharm Res	10.1023/a:1018979202933	1994
	Molecular Cloning, Expression of minD Gene from Lactobacillus acidophilus VTCC-B-871 and Analyses to Identify Lactobacillus rhamnosus PN04 from Vietnam Hottuynia cordata Thunb.	Nguyen TH, Doan VT, Ha LD, Nguyen HN.	Indian J Microbiol	10.1007/s12088-013-0384-1	2013
	MEPicides: alpha,beta-Unsaturated Fosmidomycin Analogues as DXR Inhibitors against Malaria.	Wang X, Edwards RL, Ball H, Johnson C, Haymond A, Girma M, Manikkam M, Brothers RC, McKay KT, Arnett SD, Osbourn DM, Alvarez S, Boshoff HI, Meyers MJ, Couch RD, Odom John AR, Dowd CS.	J Med Chem	10.1021/acs.jmedchem.8b01026	2018
Enzymology	Purification and biochemical characterization of streptothricin acetyltransferase coded by the cloned streptothricin-resistance gene of Streptomyces lavendulae.	Kobayashi T, Horinouchi S, Uozumi T, Beppu T.	J Antibiot (Tokyo)	10.7164/antibiotics.40.1016	1987
	Sequence and transcriptional analysis of the nourseothricin acetyltransferase-encoding gene nat1 from Streptomyces noursei.	Krugel H, Fiedler G, Smith C, Baumberg S.	Gene	10.1016/0378-1119(93)90627-f	1993
Enzymology	Comparative studies on the primary structures and inhibitory properties of subtilisin-trypsin inhibitors from Streptomyces.	Taguchi S, Kojima S, Terabe M, Miura K, Momose H.	Eur J Biochem	10.1111/j.1432-1033.1994.tb18694.x	1994
Phylogeny	Polyacrylamide gel electrophoresis analysis of ribosomal protein: a new approach for actinomycete taxonomy.	Ochi K.	Gene	10.1016/0378-1119(92)90568-a	1992
Enzymology	The structure of alanine racemase from Acinetobacter baumannii.	Davis E, Scaletti-Hutchinson E, Opel-Reading H, Nakatani Y, Krause KL.	Acta Crystallogr F Struct Biol Commun	10.1107/s2053230x14017725	2014
Enzymology	luxS in bacteria isolated from 25- to 40-million-year-old amber.	Santiago-Rodriguez TM, Patricio AR, Rivera JI, Coradin M, Gonzalez A, Tirado G, Cano RJ, Toranzos GA.	FEMS Microbiol Lett	10.1111/1574-6968.12275	2014
Metabolism	A screening method to identify antibiotics of the aminoglycoside family.	Etienne G, Armau E, Dassain M, Tiraby G.	J Antibiot (Tokyo)	10.7164/antibiotics.44.1357	1991
	Cloning and characterization of the streptothricin-resistance gene which encodes streptothricin acetyltransferase from Streptomyces lavendulae.	Kobayashi T, Uozumi T, Beppu T.	J Antibiot (Tokyo)	10.7164/antibiotics.39.688	1986
	Rational Reprogramming of O-Methylation Regioselectivity for Combinatorial Biosynthetic Tailoring of Benzenediol Lactone Scaffolds.	Wang X, Wang C, Duan L, Zhang L, Liu H, Xu YM, Liu Q, Mao T, Zhang W, Chen M, Lin M, Gunatilaka AAL, Xu Y, Molnar I.	J Am Chem Soc	10.1021/jacs.8b12967	2019
Pathogenicity	Activation and products of the cryptic secondary metabolite biosynthetic gene clusters by rifampin resistance (rpoB) mutations in actinomycetes.	Tanaka Y, Kasahara K, Hirose Y, Murakami K, Kugimiya R, Ochi K.	J Bacteriol	10.1128/jb.00147-13	2013
Enzymology	Preparation and purification of the proteinase inhibitor, leupeptin, from culture filtrates of Streptomyces lavendulae.	Ning MC, Beynon RJ.	Int J Biochem	10.1016/0020-711x(86)90058-3	1986
	Controlling the simultaneous production of laccase and lignin peroxidase from Streptomyces cinnamomensis by medium formulation.	Jing D, Wang J.	Biotechnol Biofuels	10.1186/1754-6834-5-15	2012
Enzymology	HIV-1 protease inhibitory activity of L-694,746, a novel metabolite of L-689,502.	Lingham RB, Arison BH, Colwell LF, Hsu A, Dezeny G, Thompson WJ, Garrity GM, Gagliardi MM, Hartner FW, Darke PL.	Biochem Biophys Res Commun	10.1016/0006-291x(91)92103-q	1991
Phylogeny	Heterogeneity of ribosomal proteins among Streptomyces species and its application to identification.	Ochi K.	J Gen Microbiol	10.1099/00221287-135-10-2635	1989
	Discovery of a regioselectivity switch in nitrating P450s guided by molecular dynamics simulations and Markov models.	Dodani SC, Kiss G, Cahn JK, Su Y, Pande VS, Arnold FH.	Nat Chem	10.1038/nchem.2474	2016
Metabolism	Structure elucidation and thermospray high-performance liquid chromatography/mass spectroscopy (HPLC/MS) of the microbial and mammalian metabolites of the antimalarial arteether.	Hufford CD, Lee IS, ElSohly HN, Chi HT, Baker JK.	Pharm Res	10.1023/a:1015993722846	1990
	Molecular analysis of beta-lactamases from four species of Streptomyces: comparison of amino acid sequences with those of other beta-lactamases.	Forsman M, Haggstrom B, Lindgren L, Jaurin B.	J Gen Microbiol	10.1099/00221287-136-3-589	1990
	Transcriptome analysis and identification of key genes involved in 1-deoxynojirimycin biosynthesis of mulberry (Morus alba L.).	Wang D, Zhao L, Wang D, Liu J, Yu X, Wei Y, Ouyang Z.	PeerJ	10.7717/peerj.5443	2018
Metabolism	Biosynthetic studies on saframycin A, a quinone antitumor antibiotic produced by Streptomyces lavendulae.	Mikami Y, Takahashi K, Yazawa K, Arai T, Namikoshi M, Iwasaki S, Okuda S.	J Biol Chem	10.1016/s0021-9258(18)89738-1	1985
	Isolation and characterization of a pock-forming plasmid pTA4001 from Streptomyces lavendulae.	Kobayashi T, Shimotsu H, Horinouchi S, Uozumi T, Beppu T.	J Antibiot (Tokyo)	10.7164/antibiotics.37.368	1984
Metabolism	In vitro analysis of the butyrolactone autoregulator receptor protein (FarA) of Streptomyces lavendulae FRI-5 reveals that FarA acts as a DNA-binding transcriptional regulator that controls its own synthesis.	Kitani S, Kinoshita H, Nihira T, Yamada Y.	J Bacteriol	10.1128/jb.181.16.5081-5084.1999	1999
Pathogenicity	Synthesis and Antiplasmodial Activity of Novel Fosmidomycin Derivatives and Conjugates with Artemisinin and Aminochloroquinoline.	Palla D, Antoniou AI, Baltas M, Menendez C, Grellier P, Mouray E, Athanassopoulos CM.	Molecules	10.3390/molecules25204858	2020
	Fusion of protoplasts of Streptomyces lavendulae.	Nakano MM, Ishihara H, Ogawara H.	J Antibiot (Tokyo)	10.7164/antibiotics.35.359	1982
Pathogenicity	Mitomycin resistance in Streptomyces lavendulae includes a novel drug-binding-protein-dependent export system.	Sheldon PJ, Mao Y, He M, Sherman DH.	J Bacteriol	10.1128/jb.181.8.2507-2512.1999	1999
	Cycad Coralloid Roots Contain Bacterial Communities Including Cyanobacteria and Caulobacter spp. That Encode Niche-Specific Biosynthetic Gene Clusters.	Gutierrez-Garcia K, Bustos-Diaz ED, Corona-Gomez JA, Ramos-Aboites HE, Selem-Mojica N, Cruz-Morales P, Perez-Farrera MA, Barona-Gomez F, Cibrian-Jaramillo A.	Genome Biol Evol	10.1093/gbe/evy266	2019
Metabolism	Mode of action of saframycin antitumor antibiotics: sequence selectivities in the covalent binding of saframycins A and S to deoxyribonucleic acid.	Rao KE, Lown JW.	Chem Res Toxicol	10.1021/tx00015a012	1990
Enzymology	Bioinformatic analysis reveals high diversity of bacterial genes for laccase-like enzymes.	Ausec L, Zakrzewski M, Goesmann A, Schluter A, Mandic-Mulec I.	PLoS One	10.1371/journal.pone.0025724	2011
Metabolism	Gene replacement analysis of the butyrolactone autoregulator receptor (FarA) reveals that FarA acts as a Novel regulator in secondary metabolism of Streptomyces lavendulae FRI-5.	Kitani S, Yamada Y, Nihira T.	J Bacteriol	10.1128/jb.183.14.4357-4363.2001	2001
Enzymology	Isolation and structural elucidation of new saframycins Y3, Yd-1, Yd-2, Ad-1, Y2b and Y2b-d.	Yazawa K, Takahashi K, Mikami Y, Arai T, Saito N, Kubo A.	J Antibiot (Tokyo)	10.7164/antibiotics.39.1639	1986
	FR-900098, an antimalarial development candidate that inhibits the non-mevalonate isoprenoid biosynthesis pathway, shows no evidence of acute toxicity and genotoxicity.	Wiesner J, Ziemann C, Hintz M, Reichenberg A, Ortmann R, Schlitzer M, Fuhst R, Timmesfeld N, Vilcinskas A, Jomaa H.	Virulence	10.1080/21505594.2016.1195537	2016
	Multiple effects induced by unstable mutation in Streptomyces lavendulae.	Nakano MM, Ogawara H.	J Antibiot (Tokyo)	10.7164/antibiotics.33.420	1980
Metabolism	A new antibiotic K-82 A and minor components, produced by Streptomyces lavendulae, strain No. K-82.	Shibata M, Uyeda M, Kido Y, Toya N, Nakashima R, Terazumi R.	J Antibiot (Tokyo)	10.7164/antibiotics.33.1231	1980
Metabolism	Insights into the Function of the N-Acetyltransferase SatA That Detoxifies Streptothricin in Bacillus subtilis and Bacillus anthracis.	Burckhardt RM, Escalante-Semerena JC.	Appl Environ Microbiol	10.1128/aem.03029-18	2019
	Plant-Growth Promotion and Biocontrol Properties of Three Streptomyces spp. Isolates to Control Bacterial Rice Pathogens.	Suarez-Moreno ZR, Vinchira-Villarraga DM, Vergara-Morales DI, Castellanos L, Ramos FA, Guarnaccia C, Degrassi G, Venturi V, Moreno-Sarmiento N.	Front Microbiol	10.3389/fmicb.2019.00290	2019
Enzymology	Purification and characterization of a collagenolytic enzyme from a pathogen of the great barrier reef sponge, Rhopaloeides odorabile.	Mukherjee J, Webster N, Llewellyn LE.	PLoS One	10.1371/journal.pone.0007177	2009
Enzymology	Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition.	Ballinger E, Mosior J, Hartman T, Burns-Huang K, Gold B, Morris R, Goullieux L, Blanc I, Vaubourgeix J, Lagrange S, Fraisse L, Sans S, Couturier C, Bacque E, Rhee K, Scarry SM, Aube J, Yang G, Ouerfelli O, Schnappinger D, Ioerger TR, Engelhart CA, McConnell JA, McAulay K, Fay A, Roubert C, Sacchettini J, Nathan C.	Science	10.1126/science.aau8959	2019
	SbbR/SbbA, an Important ArpA/AfsA-Like System, Regulates Milbemycin Production in Streptomyces bingchenggensis.	He H, Ye L, Li C, Wang H, Guo X, Wang X, Zhang Y, Xiang W.	Front Microbiol	10.3389/fmicb.2018.01064	2018
Metabolism	Novel glycosidase inhibitors, nojirimycin B and D-mannonic-delta-lactam. Isolation, structure determination and biological property.	Niwa T, Tsuruoka T, Goi H, Kodama Y, Itoh J, Inouye S, Yamada Y, Niida T, Nobe M, Ogawa Y.	J Antibiot (Tokyo)	10.7164/antibiotics.37.1579	1984
Pathogenicity	Characterization of a mitomycin-binding drug resistance mechanism from the producing organism, Streptomyces lavendulae.	Sheldon PJ, Johnson DA, August PR, Liu HW, Sherman DH.	J Bacteriol	10.1128/jb.179.5.1796-1804.1997	1997
Genetics	Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes.	Ju KS, Gao J, Doroghazi JR, Wang KK, Thibodeaux CJ, Li S, Metzger E, Fudala J, Su J, Zhang JK, Lee J, Cioni JP, Evans BS, Hirota R, Labeda DP, van der Donk WA, Metcalf WW.	Proc Natl Acad Sci U S A	10.1073/pnas.1500873112	2015
	Total synthesis of complestatin: development of a Pd(0)-mediated indole annulation for macrocyclization.	Shimamura H, Breazzano SP, Garfunkle J, Kimball FS, Trzupek JD, Boger DL.	J Am Chem Soc	10.1021/ja102304p	2010
Metabolism	Biochemical studies of the multicopper oxidase (small laccase) from Streptomyces coelicolor using bioactive phytochemicals and site-directed mutagenesis.	Sherif M, Waung D, Korbeci B, Mavisakalyan V, Flick R, Brown G, Abou-Zaid M, Yakunin AF, Master ER.	Microb Biotechnol	10.1111/1751-7915.12068	2013
Metabolism	Portability of the thiolation domain in recombinant pyoverdine non-ribosomal peptide synthetases.	Calcott MJ, Ackerley DF.	BMC Microbiol	10.1186/s12866-015-0496-3	2015
Enzymology	[Cholesterol breakdown by enzyme preparations extracted from Streptomyces lavendulae].	Imshenetskii AA, Nazarova TS, Nikitin LE.	Mikrobiologiia		1976
	Metabologenomics: Correlation of Microbial Gene Clusters with Metabolites Drives Discovery of a Nonribosomal Peptide with an Unusual Amino Acid Monomer.	Goering AW, McClure RA, Doroghazi JR, Albright JC, Haverland NA, Zhang Y, Ju KS, Thomson RJ, Metcalf WW, Kelleher NL.	ACS Cent Sci	10.1021/acscentsci.5b00331	2016
	Natural Products from Actinobacteria Associated with Fungus-Growing Termites.	Benndorf R, Guo H, Sommerwerk E, Weigel C, Garcia-Altares M, Martin K, Hu H, Kufner M, de Beer ZW, Poulsen M, Beemelmanns C.	Antibiotics (Basel)	10.3390/antibiotics7030083	2018
	[Discovery and development of unknown potentialities of microorganisms with special reference to saframycin group antitumor antibiotics].	Arai T.	Gan To Kagaku Ryoho		1984
Metabolism	Characterization of hydrocortisone biometabolites and 18S rRNA gene in Chlamydomonas reinhardtii cultures.	Ghasemi Y, Rasoul-Amini S, Morowvat MH, Raee MJ, Ghoshoon MB, Nouri F, Negintaji N, Parvizi R, Mosavi-Azam SB.	Molecules	10.3390/molecules13102416	2008
	The structure of a novel antitumor antibiotic, saframycin A.	Arai T, Takahashi K, Nakahara S, Kubo A.	Experientia	10.1007/bf01965946	1980
	Inadequate efficacy of a new formulation of fosmidomycin-clindamycin combination in Mozambican children less than three years old with uncomplicated Plasmodium falciparum malaria.	Lanaspa M, Moraleda C, Machevo S, Gonzalez R, Serrano B, Macete E, Cistero P, Mayor A, Hutchinson D, Kremsner PG, Alonso P, Menendez C, Bassat Q.	Antimicrob Agents Chemother	10.1128/aac.00018-12	2012
Metabolism	Isolation and characterization of satellite antibiotics, mimosamycin and chlorocarcins from Streptomyces lavendulae, streptothricin source.	Arai T, Yazawa K, Mikami Y.	J Antibiot (Tokyo)	10.7164/antibiotics.29.398	1976
	Recombination between short direct repeats in Streptomyces lavendulae plasmid DNA.	Nakano MM, Ogawara H, Sekiya T.	J Bacteriol	10.1128/jb.157.2.658-660.1984	1984
Metabolism	Characterization of a quinone reductase activity for the mitomycin C binding protein (MRD): Functional switching from a drug-activating enzyme to a drug-binding protein.	He M, Sheldon PJ, Sherman DH.	Proc Natl Acad Sci U S A	10.1073/pnas.98.3.926	2001
Enzymology	Characterization of a novel DNA glycosylase from S. sahachiroi involved in the reduction and repair of azinomycin B induced DNA damage.	Wang S, Liu K, Xiao L, Yang L, Li H, Zhang F, Lei L, Li S, Feng X, Li A, He J.	Nucleic Acids Res	10.1093/nar/gkv949	2016
	Detection and quantification of a mycorrhization helper bacterium and a mycorrhizal fungus in plant-soil microcosms at different levels of complexity.	Kurth F, Zeitler K, Feldhahn L, Neu TR, Weber T, Kristufek V, Wubet T, Herrmann S, Buscot F, Tarkka MT.	BMC Microbiol	10.1186/1471-2180-13-205	2013
Enzymology	Functional expression of a penicillin acylase from the extreme thermophile Thermus thermophilus HB27 in Escherichia coli.	Torres LL, Ferreras ER, Cantero A, Hidalgo A, Berenguer J.	Microb Cell Fact	10.1186/1475-2859-11-105	2012
	Identification of a Pantoea biosynthetic cluster that directs the synthesis of an antimicrobial natural product.	Walterson AM, Smith DD, Stavrinides J.	PLoS One	10.1371/journal.pone.0096208	2014
	Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster.	Chiu HT, Hubbard BK, Shah AN, Eide J, Fredenburg RA, Walsh CT, Khosla C.	Proc Natl Acad Sci U S A	10.1073/pnas.151246498	2001
Metabolism	Mitomycin resistance in mammalian cells expressing the bacterial mitomycin C resistance protein MCRA.	Belcourt MF, Penketh PG, Hodnick WF, Johnson DA, Sherman DH, Rockwell S, Sartorelli AC.	Proc Natl Acad Sci U S A	10.1073/pnas.96.18.10489	1999
Metabolism	In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.	Ottavi S, Scarry SM, Mosior J, Ling Y, Roberts J, Singh A, Zhang D, Goullieux L, Roubert C, Bacque E, Lagiakos HR, Vendome J, Moraca F, Li K, Perkowski AJ, Ramesh R, Bowler MM, Tracy W, Feher VA, Sacchettini JC, Gold BS, Nathan CF, Aube J.	J Med Chem	10.1021/acs.jmedchem.1c01565	2022
Enzymology	Studies on new phosphonic acid antibiotics. III. Isolation and characterization of FR-31564, FR-32863 and FR-33289.	Okuhara M, Kuroda Y, Goto T, Okamoto M, Terano H, Kohsaka M, Aoki H, Imanaka H.	J Antibiot (Tokyo)	10.7164/antibiotics.33.24	1980
Metabolism	Increased production of saframycin A and isolation of saframycin S.	Arai T, Takahashi K, Ishiguro K, Yazawa K.	J Antibiot (Tokyo)	10.7164/antibiotics.33.951	1980
Metabolism	Studies on new phosphonic acid antibiotics. II. Taxonomic studies on producing organisms of the phosphonic acid and related compounds.	Iguchi E, Okuhara M, Kohsaka M, Aoki H, Imanaka H.	J Antibiot (Tokyo)	10.7164/antibiotics.33.18	1980
Metabolism	Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743.	Rath CM, Janto B, Earl J, Ahmed A, Hu FZ, Hiller L, Dahlgren M, Kreft R, Yu F, Wolff JJ, Kweon HK, Christiansen MA, Hakansson K, Williams RM, Ehrlich GD, Sherman DH.	ACS Chem Biol	10.1021/cb200244t	2011
Enzymology	Cloning and analysis of a locus (mcr) involved in mitomycin C resistance in Streptomyces lavendulae.	August PR, Flickinger MC, Sherman DH.	J Bacteriol	10.1128/jb.176.14.4448-4454.1994	1994
Metabolism	Green methods of lignocellulose pretreatment for biorefinery development.	Capolupo L, Faraco V.	Appl Microbiol Biotechnol	10.1007/s00253-016-7884-y	2016
	Methyl 1-(7-acetamido-5,8-dimeth-oxy-quinolin-2-yl)-4-methyl-beta-carboline-3-carboxyl-ate.	Nissen F, Schollmeyer D, Detert H.	Acta Crystallogr Sect E Struct Rep Online	10.1107/s1600536811018794	2011
Enzymology	I. Isolation and characterization of the transformation products of maridomycin III.	Shibata M, Uyeda M, Mori S.	J Antibiot (Tokyo)	10.7164/antibiotics.28.434	1975
Metabolism	Identification of producer and biological activities of new antibiotics, mimosamycin and chlorocarcins.	Mikami Y, Yokoyama K, Omi A, Arai T.	J Antibiot (Tokyo)	10.7164/antibiotics.29.408	1976
Enzymology	Engineering the substrate specificity of a thermophilic penicillin acylase from thermus thermophilus.	Torres LL, Cantero A, del Valle M, Marina A, Lopez-Gallego F, Guisan JM, Berenguer J, Berenguer J, Hidalgo A.	Appl Environ Microbiol	10.1128/aem.03215-12	2013
	alpha,beta-Dehydroamino acids in naturally occurring peptides.	Siodlak D.	Amino Acids	10.1007/s00726-014-1846-4	2015
Metabolism	Deciphering the late biosynthetic steps of antimalarial compound FR-900098.	Johannes TW, DeSieno MA, Griffin BM, Thomas PM, Kelleher NL, Metcalf WW, Zhao H.	Chem Biol	10.1016/j.chembiol.2009.12.009	2010
Metabolism	Fum3p, a 2-ketoglutarate-dependent dioxygenase required for C-5 hydroxylation of fumonisins in Fusarium verticillioides.	Ding Y, Bojja RS, Du L.	Appl Environ Microbiol	10.1128/aem.70.4.1931-1934.2004	2004
Metabolism	Directed biosynthesis of new saframycin derivatives with resting cells of Streptomyces lavendulae.	Arai T, Yazawa K, Takahashi K, Maeda A, Mikami Y.	Antimicrob Agents Chemother	10.1128/aac.28.1.5	1985
Enzymology	Structures of an alanine racemase from Bacillus anthracis (BA0252) in the presence and absence of (R)-1-aminoethylphosphonic acid (L-Ala-P).	Au K, Ren J, Walter TS, Harlos K, Nettleship JE, Owens RJ, Stuart DI, Esnouf RM.	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/s1744309108007252	2008
Metabolism	Alkane inducible proteins in Geobacillus thermoleovorans B23.	Kato T, Miyanaga A, Kanaya S, Morikawa M.	BMC Microbiol	10.1186/1471-2180-9-60	2009
Metabolism	The actinomycin biosynthetic gene cluster of Streptomyces chrysomallus: a genetic hall of mirrors for synthesis of a molecule with mirror symmetry.	Keller U, Lang M, Crnovcic I, Pfennig F, Schauwecker F.	J Bacteriol	10.1128/jb.01526-09	2010
Enzymology	Unstable mutation of beta-lactamase production in Streptomyces lavendulae.	Matsubara-Nakano M, Kataoka Y, Ogawara H.	Antimicrob Agents Chemother	10.1128/aac.17.2.124	1980
Enzymology	Synthesis of a 3-Amino-2,3-dihydropyrid-4-one and Related Heterocyclic Analogues as Mechanism-Based Inhibitors of BioA, a Pyridoxal Phosphate-Dependent Enzyme.	Eiden CG, Aldrich CC.	J Org Chem	10.1021/acs.joc.7b00847	2017
Metabolism	Production of the antimicrobial secondary metabolite indigoidine contributes to competitive surface colonization by the marine roseobacter Phaeobacter sp. strain Y4I.	Cude WN, Mooney J, Tavanaei AA, Hadden MK, Frank AM, Gulvik CA, May AL, Buchan A.	Appl Environ Microbiol	10.1128/aem.00297-12	2012
	Synthesis and biological evaluation of a phosphonate analog of the natural acetyl cholinesterase inhibitor cyclophostin.	Bandyopadhyay S, Dutta S, Spilling CD, Dupureur CM, Rath NP.	J Org Chem	10.1021/jo801453v	2008
Enzymology	Genetic localization and molecular characterization of two key genes (mitAB) required for biosynthesis of the antitumor antibiotic mitomycin C.	Mao Y, Varoglu M, Sherman DH.	J Bacteriol	10.1128/jb.181.7.2199-2208.1999	1999
Enzymology	Biochemical and structural characterization of alanine racemase from Bacillus anthracis (Ames).	Counago RM, Davlieva M, Strych U, Hill RE, Krause KL.	BMC Struct Biol	10.1186/1472-6807-9-53	2009
Metabolism	Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes.	Foulston LC, Bibb MJ.	Proc Natl Acad Sci U S A	10.1073/pnas.1008285107	2010
	Fungal laccases and their applications in bioremediation.	Viswanath B, Rajesh B, Janardhan A, Kumar AP, Narasimha G.	Enzyme Res	10.1155/2014/163242	2014
Enzymology	Structural and kinetic studies on RosA, the enzyme catalysing the methylation of 8-demethyl-8-amino-d-riboflavin to the antibiotic roseoflavin.	Tongsook C, Uhl MK, Jankowitsch F, Mack M, Gruber K, Macheroux P.	FEBS J	10.1111/febs.13690	2016
Metabolism	Andrimid producers encode an acetyl-CoA carboxyltransferase subunit resistant to the action of the antibiotic.	Liu X, Fortin PD, Walsh CT.	Proc Natl Acad Sci U S A	10.1073/pnas.0806873105	2008
Metabolism	Mannitol oxidation in two Micromonospora isolates and in representative species of other actinomycetes.	Mehta RJ, Fare LR, Shearer ME, Nash CH.	Appl Environ Microbiol	10.1128/aem.33.4.1013-1015.1977	1977
Metabolism	Extracellular Streptomyces vesicles: amphorae for survival and defence.	Schrempf H, Koebsch I, Walter S, Engelhardt H, Meschke H.	Microb Biotechnol	10.1111/j.1751-7915.2011.00251.x	2011
	Evolutionary relationships among actinophages and a putative adaptation for growth in Streptomyces spp.	Smith MC, Hendrix RW, Dedrick R, Mitchell K, Ko CC, Russell D, Bell E, Gregory M, Bibb MJ, Pethick F, Jacobs-Sera D, Herron P, Buttner MJ, Hatfull GF.	J Bacteriol	10.1128/jb.00618-13	2013
	Synthesis of new quinolinequinone derivatives and preliminary exploration of their cytotoxic properties.	Keyari CM, Kearns AK, Duncan NS, Eickholt EA, Abbott G, Beall HD, Diaz P.	J Med Chem	10.1021/jm301689x	2013
Metabolism	The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.	Medema MH, Trefzer A, Kovalchuk A, van den Berg M, Muller U, Heijne W, Wu L, Alam MT, Ronning CM, Nierman WC, Bovenberg RA, Breitling R, Takano E.	Genome Biol Evol	10.1093/gbe/evq013	2010
Metabolism	"Pseudo" gamma-butyrolactone receptors respond to antibiotic signals to coordinate antibiotic biosynthesis.	Xu G, Wang J, Wang L, Tian X, Yang H, Fan K, Yang K, Tan H.	J Biol Chem	10.1074/jbc.m110.143081	2010
	Nucleotide sequence of the streptothricin acetyltransferase gene from Streptomyces lavendulae and its expression in heterologous hosts.	Horinouchi S, Furuya K, Nishiyama M, Suzuki H, Beppu T.	J Bacteriol	10.1128/jb.169.5.1929-1937.1987	1987
Metabolism	Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression.	Woong Park S, Klotzsche M, Wilson DJ, Boshoff HI, Eoh H, Manjunatha U, Blumenthal A, Rhee K, Barry CE, Aldrich CC, Ehrt S, Schnappinger D.	PLoS Pathog	10.1371/journal.ppat.1002264	2011
Enzymology	Crystal structures of lysine-preferred racemases, the non-antibiotic selectable markers for transgenic plants.	Wu HM, Kuan YC, Chu CH, Hsu WH, Wang WC.	PLoS One	10.1371/journal.pone.0048301	2012
Pathogenicity	Lipophilic prodrugs of FR900098 are antimicrobial against Francisella novicida in vivo and in vitro and show GlpT independent efficacy.	McKenney ES, Sargent M, Khan H, Uh E, Jackson ER, San Jose G, Couch RD, Dowd CS, van Hoek ML.	PLoS One	10.1371/journal.pone.0038167	2012
Enzymology	The crystal structure of alanine racemase from Streptococcus pneumoniae, a target for structure-based drug design.	Im H, Sharpe ML, Strych U, Davlieva M, Krause KL.	BMC Microbiol	10.1186/1471-2180-11-116	2011
Metabolism	Pleiotropic control of secondary metabolism and morphological development by KsbC, a butyrolactone autoregulator receptor homologue in Kitasatospora setae.	Aroonsri A, Kitani S, Hashimoto J, Kosone I, Izumikawa M, Komatsu M, Fujita N, Takahashi Y, Shin-ya K, Ikeda H, Nihira T.	Appl Environ Microbiol	10.1128/aem.02355-12	2012
Pathogenicity	Characterization of sparsomycin resistance in Streptomyces sparsogenes.	Lazaro E, Sanz E, Remacha M, Ballesta JP.	Antimicrob Agents Chemother	10.1128/aac.46.9.2914-2919.2002	2002
	Endophytic and epiphytic microbes as "sources" of bioactive agents.	Newman DJ, Cragg GM.	Front Chem	10.3389/fchem.2015.00034	2015
Pathogenicity	Cloning of the kanamycin resistance gene from a kanamycin-producing Streptomyces species.	Nakano MM, Mashiko H, Ogawara H.	J Bacteriol	10.1128/jb.157.1.79-83.1984	1984
Metabolism	Expression of the Streptomyces coelicolor SoxR regulon is intimately linked with actinorhodin production.	Dela Cruz R, Gao Y, Penumetcha S, Sheplock R, Weng K, Chander M.	J Bacteriol	10.1128/jb.00916-10	2010
Pathogenicity	Characterization of Escherichia coli D-cycloserine transport and resistant mutants.	Baisa G, Stabo NJ, Welch RA.	J Bacteriol	10.1128/jb.01598-12	2013
Enzymology	Halogenase genes in nonribosomal peptide synthetase gene clusters of Microcystis (cyanobacteria): sporadic distribution and evolution.	Cadel-Six S, Dauga C, Castets AM, Rippka R, Bouchier C, Tandeau de Marsac N, Welker M.	Mol Biol Evol	10.1093/molbev/msn150	2008
Metabolism	LccA, an archaeal laccase secreted as a highly stable glycoprotein into the extracellular medium by Haloferax volcanii.	Uthandi S, Saad B, Humbard MA, Maupin-Furlow JA.	Appl Environ Microbiol	10.1128/aem.01757-09	2010
Pathogenicity	Synthesis and biological evaluation of 1,4-naphthoquinones and quinoline-5,8-diones as antimalarial and schistosomicidal agents.	Lanfranchi DA, Cesar-Rodo E, Bertrand B, Huang HH, Day L, Johann L, Elhabiri M, Becker K, Williams DL, Davioud-Charvet E.	Org Biomol Chem	10.1039/c2ob25812a	2012
Metabolism	Biosynthesis of fusarubins accounts for pigmentation of Fusarium fujikuroi perithecia.	Studt L, Wiemann P, Kleigrewe K, Humpf HU, Tudzynski B.	Appl Environ Microbiol	10.1128/aem.00823-12	2012
Pathogenicity	Chronic adjunction of 1-deoxynojirimycin protects from age-related behavioral and biochemical changes in the SAMP8 mice.	Chen GH, Tong JJ, Wang F, Hu XQ, Li XW, Tao F, Wei ZJ.	Age (Dordr)	10.1007/s11357-015-9839-0	2015
Metabolism	Bacterial endosymbiosis in a chordate host: long-term co-evolution and conservation of secondary metabolism.	Kwan JC, Schmidt EW.	PLoS One	10.1371/journal.pone.0080822	2013
Metabolism	Characterization of pyoverdine and achromobactin in Pseudomonas syringae pv. phaseolicola 1448a.	Owen JG, Ackerley DF.	BMC Microbiol	10.1186/1471-2180-11-218	2011
Genetics	Complete genome sequence and lifestyle of black-pigmented Corynebacterium aurimucosum ATCC 700975 (formerly C. nigricans CN-1) isolated from a vaginal swab of a woman with spontaneous abortion.	Trost E, Gotker S, Schneider J, Schneiker-Bekel S, Szczepanowski R, Tilker A, Viehoever P, Arnold W, Bekel T, Blom J, Gartemann KH, Linke B, Goesmann A, Puhler A, Shukla SK, Tauch A.	BMC Genomics	10.1186/1471-2164-11-91	2010
	A bistable gene switch for antibiotic biosynthesis: the butyrolactone regulon in Streptomyces coelicolor.	Mehra S, Charaniya S, Takano E, Hu WS.	PLoS One	10.1371/journal.pone.0002724	2008
Metabolism	The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum.	Yu TW, Bai L, Clade D, Hoffmann D, Toelzer S, Trinh KQ, Xu J, Moss SJ, Leistner E, Floss HG.	Proc Natl Acad Sci U S A	10.1073/pnas.092697199	2002
Metabolism	Requirement of DNA repair mechanisms for survival of Burkholderia cepacia G4 upon degradation of trichloroethylene.	Yeager CM, Bottomley PJ, Arp DJ.	Appl Environ Microbiol	10.1128/aem.67.12.5384-5391.2001	2001
Phylogeny	Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution.	Rausch C, Hoof I, Weber T, Wohlleben W, Huson DH.	BMC Evol Biol	10.1186/1471-2148-7-78	2007
Metabolism	Involvement of a cytochrome P450 monooxygenase in thaxtomin A biosynthesis by Streptomyces acidiscabies.	Healy FG, Krasnoff SB, Wach M, Gibson DM, Loria R.	J Bacteriol	10.1128/jb.184.7.2019-2029.2002	2002
Metabolism	Cloning of a genetically unstable cytochrome P-450 gene cluster involved in degradation of the pollutant ethyl tert-butyl ether by Rhodococcus ruber.	Chauvaux S, Chevalier F, Le Dantec C, Fayolle F, Miras I, Kunst F, Beguin P.	J Bacteriol	10.1128/jb.183.22.6551-6557.2001	2001
	Synthesis and kinetic evaluation of cyclophostin and cyclipostins phosphonate analogs as selective and potent inhibitors of microbial lipases.	Point V, Malla RK, Diomande S, Martin BP, Delorme V, Carriere F, Canaan S, Rath NP, Spilling CD, Cavalier JF.	J Med Chem	10.1021/jm301216x	2012
Metabolism	CcaR is an autoregulatory protein that binds to the ccaR and cefD-cmcI promoters of the cephamycin C-clavulanic acid cluster in Streptomyces clavuligerus.	Santamarta I, Rodriguez-Garcia A, Perez-Redondo R, Martin JF, Liras P.	J Bacteriol	10.1128/jb.184.11.3106-3113.2002	2002
	Synthesis, metabolism and in vitro cytotoxicity studies on novel lavendamycin antitumor agents.	Cai W, Hassani M, Karki R, Walter ED, Koelsch KH, Seradj H, Lineswala JP, Mirzaei H, York JS, Olang F, Sedighi M, Lucas JS, Eads TJ, Rose AS, Charkhzarrin S, Hermann NG, Beall HD, Behforouz M.	Bioorg Med Chem	10.1016/j.bmc.2010.01.037	2010
	Intravesical Bacillus Calmette-Guérin versus mitomycin C for Ta and T1 bladder cancer.	Schmidt S, Kunath F, Coles B, Draeger DL, Krabbe LM, Dersch R, Kilian S, Jensen K, Dahm P, Meerpohl JJ.	Cochrane Database Syst Rev	10.1002/14651858.cd011935.pub2	2020
	Mitomycins syntheses: a recent update.	Andrez JC.	Beilstein J Org Chem	10.3762/bjoc.5.33	2009
Metabolism	Regulation of the Streptomyces coelicolor calcium-dependent antibiotic by absA, encoding a cluster-linked two-component system.	Ryding NJ, Anderson TB, Champness WC.	J Bacteriol	10.1128/jb.184.3.794-805.2002	2002
Metabolism	Characterization of indigoidine biosynthetic genes in Erwinia chrysanthemi and role of this blue pigment in pathogenicity.	Reverchon S, Rouanet C, Expert D, Nasser W.	J Bacteriol	10.1128/jb.184.3.654-665.2002	2002
Metabolism	Characterization of the protocatechuic acid catabolic gene cluster from Streptomyces sp. strain 2065.	Iwagami SG, Yang K, Davies J.	Appl Environ Microbiol	10.1128/aem.66.4.1499-1508.2000	2000
	Synthesis and evaluation of antitumor activity of novel N-acyllavendamycin analogues and quinoline-5,8-diones.	Behforouz M, Cai W, Mohammadi F, Stocksdale MG, Gu Z, Ahmadian M, Baty DE, Etling MR, Al-Anzi CH, Swiftney TM, Tanzer LR, Merriman RL, Behforouz NC.	Bioorg Med Chem	10.1016/j.bmc.2006.09.039	2007
Metabolism	Functional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1.	Mavrodi DV, Bonsall RF, Delaney SM, Soule MJ, Phillips G, Thomashow LS.	J Bacteriol	10.1128/jb.183.21.6454-6465.2001	2001
	Natural products synthesis: enabling tools to penetrate Nature's secrets of biogenesis and biomechanism.	Williams RM.	J Org Chem	10.1021/jo2003693	2011
Phylogeny	Analysis and functional classification of transcripts from the nematode Meloidogyne incognita.	McCarter JP, Mitreva MD, Martin J, Dante M, Wylie T, Rao U, Pape D, Bowers Y, Theising B, Murphy CV, Kloek AP, Chiapelli BJ, Clifton SW, Bird DM, Waterston RH.	Genome Biol	10.1186/gb-2003-4-4-r26	2003
Genetics	Genome-Based Taxonomic Classification of the Phylum Actinobacteria.	Nouioui I, Carro L, Garcia-Lopez M, Meier-Kolthoff JP, Woyke T, Kyrpides NC, Pukall R, Klenk HP, Goodfellow M, Goker M.	Front Microbiol	10.3389/fmicb.2018.02007	2018
Enzymology	Functional characterisation of twelve terpene synthases from actinobacteria.	Chhalodia AK, Xu H, Tabekoueng GB, Gu B, Taizoumbe KA, Lauterbach L, Dickschat JS.	Beilstein J Org Chem	10.3762/bjoc.19.100	2023
	Modifications of diketopiperazines assembled by cyclodipeptide synthases with cytochrome P450 enzymes.	Harken L, Li SM.	Appl Microbiol Biotechnol	10.1007/s00253-021-11178-1	2021
Metabolism	Denitrification by actinomycetes and purification of dissimilatory nitrite reductase and azurin from Streptomyces thioluteus.	Shoun H, Kano M, Baba I, Takaya N, Matsuo M.	J Bacteriol	10.1128/jb.180.17.4413-4415.1998	1998
Phylogeny	Real-time PCR for the detection and quantification of geodermatophilaceae from stone samples and identification of new members of the genus blastococcus.	Salazar O, Valverde A, Genilloud O.	Appl Environ Microbiol	10.1128/aem.72.1.346-352.2006	2006
Enzymology	A new site-specific endonuclease from Streptomyces lavendulae (SlaI).	Takahashi H, Shimizu M, Saito H, Ikeda Y, Sugisaki H	Gene	10.1016/0378-1119(79)90089-1	1979
Genetics	Streptomyces antarcticus sp. nov., isolated from Horseshoe Island, Antarctica.	Sahin SM, Saticioglu IB, Duman M, Ay H.	Int J Syst Evol Microbiol	10.1099/ijsem.0.006856	2025
Phylogeny	Reclassification of four subspecies in the genus Streptomyces to Streptomyces rubradiris sp. nov., Streptomyces asoensis sp. nov., Streptomyces fructofermentans sp. nov. and Streptomyces ossamyceticus sp. nov.	Komaki H, Tamura T	Int J Syst Evol Microbiol	10.1099/ijsem.0.005078	2021