Streptomyces hiroshimensis 201 is an obligate aerobe, spore-forming, mesophilic prokaryote that builds an aerial mycelium and was isolated from soil.
spore-forming Gram-positive rod-shaped obligate aerobe mesophilic genome sequence 16S sequence
SI-ID 38289
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 9116 | GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) | Medium recipe at MediaDive  | Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water | ||
| 19391 | ISP 2 | Name: ISP 2 / Yeast Malt Agar (5265); 5265 Composition Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l Agar 15.0 g/l Preparation: Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.0 Usage: Maintenance and Taxonomy Organisms: All Actinomycetes | |||
| 19391 | ISP 3 | Name: ISP 3; 5315 Composition Dog oat flakes 20.0 g/l Trace element solution (5314) 2.5 ml/l Agar 18.0 g/l Preparation: Oat flakes are cooked for 20 minutes, trace element solution and agar are added (in the case of non rolled oat flakes the suspension has to bee filtrated). Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.8 Usage: Maintenance and taxonomy (e.g. SEM As liquid medium for metabolite production) Organisms: All Actinomycetes Trace element solution 5314 Name: Trace element solution 5314; 5314 Composition CaCl2 x H2O 3.0 g/l Fe-III-citrate 1.0 g/l MnSO4 0.2 g/l ZnCl2 0.1 g/l CuSO4 x 5 H2O 0.025 g/l Sodium tetra borate 0.2 g/l CoCl2 x 6 H2O 0.004 g/l Sodium molybdate 0.01 g/l Preparation: Use double destillated water. Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Trace element solution for different media Organisms: | |||
| 19391 | ISP 4 | Name: ISP 4; DSM 547 Solution I: Difco soluble starch, 10.0 g. Make a paste of the starch with a small amount of cold distilled water and bring to a volume of 500 ml. Solution II: CaCO3 2.0 g K2HPO4 (anhydrous) 1.0 g MgSO4 x 7 H2O 1.0 g NaCl 1.0 g (NH4)2SO4 2.0 g Distilled water 500.0 ml Trace salt solution (see below) 1.0 ml The pH should be between 7.0 and 7.4. Do not adjust if it is within this range. Mix solutions I and II together. Add 20.0 g agar. Liquify agar by steaming at 100°C for 10 to 20 min. Trace element solution: FeSO4 x 7 H2O 0.1 g MnCl2 x 4 H2O 0.1 g ZnSO4 x 7 H2O 0.1 g Distilled water 100.0 ml | |||
| 19391 | ISP 5 | Name: ISP 5 (5323) Composition L-Asparagine 1.0 g/l Glycerol 10.0 g/l K2HPO4 1.0 g/l Salt solution (see preparation) 1.0 ml/l Agar 20.0 g/l Preparation: Salt solution 1.0 g FeSO4 x 7 H2O 1.0 g MnCl2 x 4 H2O 1.0 g ZNSO4 x 7 H2O in 100 ml water Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.2 Usage: Maintenance and taxonomy Organisms: All Actinomycetes | |||
| 19391 | ISP 6 | Name: ISP 6 (5318) Composition Peptone 15.0 g/l Proteose peptose 5.0 g/l Ferric ammonium citrate 0.5 g/l Sodium glycerophosphate 1.0 g/l Sodium thiosulfate 0.08 g/l Yeast extract 1.0 g/l Agar 15.0 g/l Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Production of melanoid pigments Organisms: All Actinomycetes | |||
| 19391 | ISP 7 | Name: ISP 7 (5322) Composition Glycerol 15.0 g/l L-Tyrosine 0.5 g/l L-Asparagine 1.0 g/l K2HPO4 0.5 g/l NaCl 0.5 g/l FeSO4 x 7 H2O 0.01 g/l Trace element solution 5343 1.0 ml/l Agar 20.0 Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.3 Usage: Production of melanoid pigments Organisms: All Actinomycetes | |||
| 37416 | MEDIUM 57 - for Streptomyces, Nocardioides, Lentzea albidocapillata and Streptoverticillium reticulum | Distilled water make up to (1000.000 ml);Agar (15.000 g);Glucose (4.000g);Yeast extract (4.000 g);Malt extract (10.000 g);Calcium carbonate (2.000 g) | |||
| 9116 | ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84) | Medium recipe at MediaDive | Name: ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84) Composition: Agar 20.0 g/l Rolled oats 20.0 g/l ZnSO4 x 7 H2O 0.001 g/l MnCl2 x 4 H2O 0.001 g/l FeSO4 x 7 H2O 0.001 g/l Distilled water | ||
| 119910 | CIP Medium 57 | Medium recipe at CIP |
| @ref | Compound | Percentage | |
|---|---|---|---|
| 19391 | Lysozyme | 1 |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 19391 | 22599 ChEBI | arabinose | - | ||
| 68368 | 29016 ChEBI | arginine | - | hydrolysis | from API 20E |
| 19391 | 62968 ChEBI | cellulose | - | ||
| 119910 | 16947 ChEBI | citrate | - | carbon source | |
| 68368 | 16947 ChEBI | citrate | - | assimilation | from API 20E |
| 119910 | 4853 ChEBI | esculin | + | hydrolysis | |
| 19391 | 28757 ChEBI | fructose | - | ||
| 68368 | 5291 ChEBI | gelatin | - | hydrolysis | from API 20E |
| 19391 | 17234 ChEBI | glucose | + | ||
| 68368 | 25094 ChEBI | lysine | - | degradation | from API 20E |
| 19391 | 29864 ChEBI | mannitol | - | ||
| 19391 | 17268 ChEBI | myo-inositol | - | ||
| 119910 | 17632 ChEBI | nitrate | - | reduction | |
| 119910 | 17632 ChEBI | nitrate | - | respiration | |
| 119910 | 16301 ChEBI | nitrite | - | reduction | |
| 68368 | 18257 ChEBI | ornithine | - | degradation | from API 20E |
| 19391 | 16634 ChEBI | raffinose | - | ||
| 19391 | 26546 ChEBI | rhamnose | - | ||
| 19391 | 17992 ChEBI | sucrose | - | ||
| 68368 | 27897 ChEBI | tryptophan | - | energy source | from API 20E |
| 68368 | 16199 ChEBI | urea | - | hydrolysis | from API 20E |
| 19391 | 18222 ChEBI | xylose | - |
| @ref | Metabolite | Is sensitive | Is resistant | |
|---|---|---|---|---|
| 119910 | 0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate) |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 119910 | alcohol dehydrogenase | - | 1.1.1.1 | |
| 68382 | alkaline phosphatase | + | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | - | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 119910 | amylase | + | ||
| 68368 | arginine dihydrolase | - | 3.5.3.6 | from API 20E |
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 119910 | beta-galactosidase | - | 3.2.1.23 | |
| 68368 | beta-galactosidase | - | 3.2.1.23 | from API 20E |
| 68382 | beta-glucosidase | - | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 119910 | caseinase | - | 3.4.21.50 | |
| 119910 | catalase | + | 1.11.1.6 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 119910 | DNase | - | ||
| 68382 | esterase (C 4) | + | from API zym | |
| 68382 | esterase lipase (C 8) | + | from API zym | |
| 119910 | gelatinase | +/- | ||
| 68368 | gelatinase | - | from API 20E | |
| 119910 | lecithinase | + | ||
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 119910 | lipase | - | ||
| 68382 | lipase (C 14) | - | from API zym | |
| 119910 | lysine decarboxylase | - | 4.1.1.18 | |
| 68368 | lysine decarboxylase | - | 4.1.1.18 | from API 20E |
| 68382 | N-acetyl-beta-glucosaminidase | + | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 119910 | ornithine decarboxylase | - | 4.1.1.17 | |
| 68368 | ornithine decarboxylase | - | 4.1.1.17 | from API 20E |
| 119910 | oxidase | - | ||
| 119910 | phenylalanine ammonia-lyase | - | 4.3.1.24 | |
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 119910 | tryptophan deaminase | - | ||
| 68368 | tryptophan deaminase | - | 4.1.99.1 | from API 20E |
| 119910 | tween esterase | + | ||
| 119910 | urease | - | 3.5.1.5 | |
| 68368 | urease | - | 3.5.1.5 | from API 20E |
| 68382 | valine arylamidase | - | from API zym |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 66792 | ASM1465033v1 assembly for Streptomyces hiroshimensis JCM 4586 | scaffold | GCA_014650335   | 66424.5  | 2989981811  | 66424 | 67.95 | |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 20218 | Streptomyces hiroshimensis strain CGMCC 4.1948 16S ribosomal RNA gene, partial sequence | HQ244459 | 1488 |  | 66424 | |
| 20218 | Streptomyces hiroshimensis gene for 16S ribosomal RNA, partial sequence, strain: JCM 4098 | D44005 | 120 | | 66424 | |
| 20218 | Streptomyces hiroshimensis gene for 16S rRNA, partial sequence, strain: NBRC 12785 | AB184144 | 1429 | | 66424 | |
| 20218 | Streptomyces hiroshimensis strain NBRC 12785 16S ribosomal RNA gene, partial sequence | JN566033 | 1488 | | 66424 | |
| 20218 | Streptomyces hiroshimensis gene for 16S rRNA, partial sequence, strain: NBRC 3720 | AB184789 | 1467 | | 66424 | |
| 20218 | Streptomyces hiroshimensis gene for 16S rRNA, partial sequence, strain: NBRC 3839 | AB184802 | 1454 | | 66424 | |
| 20218 | Streptomyces hiroshimensis strain NRRL B-1823 16S ribosomal RNA gene, partial sequence | EF178677 | 1325 | | 66424 | |
| 124043 | Streptomyces hiroshimensis strain JCM 4586 16S ribosomal RNA gene, partial sequence. | MT760577 | 1389 | | 66424 | |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Enzymology | Scope and Synthetic Applications of the Aryl-Alcohol Oxidase from Streptomyces hiroshimensis (ShAAO). | Ascaso-Alegre C, Cinca-Fernando P, Roberts TL, Lopez-Fernandez P, Herrera RP, Cosgrove SC, Ferreira P, Mangas-Sanchez J. | Org Lett | 10.1021/acs.orglett.5c03814 | 2025 | |
| Hirocidins, Cytotoxic Metabolites from Streptomyces hiroshimensis, Induce Mitochondrion-Mediated Apoptosis. | Han EJ, Jeong M, Lee SR, Sorensen EJ, Seyedsayamdost MR. | Angew Chem Int Ed Engl | 10.1002/anie.202405367 | 2024 | | |
| Integration of Transcriptomics and Proteomics to Elucidate Inhibitory Effect and Mechanism of Antifungalmycin B from Marine Streptomyces hiroshimensis in Treating Talaromyces marneffei. | Li Q, Wang Z, Jiang C, Yin J, Liu Y, Qu X, Yi X, Gao C. | Mar Drugs | 10.3390/md23020076 | 2025 | | |
| Enzymology | ARTP mutagenesis of phospholipase D-producing strain Streptomyces hiroshimensis SK43.001, and its enzymatic properties. | Li C, Xia Y, Li M, Zhang T. | Heliyon | 10.1016/j.heliyon.2022.e12587 | 2022 | |
| New Polyene Macrolide Compounds from Mangrove-Derived Strain Streptomyces hiroshimensis GXIMD 06359: Isolation, Antifungal Activity, and Mechanism against Talaromyces marneffei. | Wang Z, Yin J, Bai M, Yang J, Jiang C, Yi X, Liu Y, Gao C. | Mar Drugs | 10.3390/md22010038 | 2024 | | |
| Enzymology | Discovery, characterization, and synthetic potential of two novel bacterial aryl-alcohol oxidases. | Cinca-Fernando P, Ascaso-Alegre C, Sevilla E, Martinez-Julvez M, Mangas-Sanchez J, Ferreira P. | Appl Microbiol Biotechnol | 10.1007/s00253-024-13314-z | 2024 | |
| Metabolism | Characterization of the N-methyltransferases involved in the biosynthesis of toxoflavin, fervenulin and reumycin from Streptomyces hiroshimensis ATCC53615. | Su C, Yan Y, Guo X, Luo J, Liu C, Zhang Z, Xiang WS, Huang SX. | Org Biomol Chem | 10.1039/c8ob02847h | 2019 | |
| Transcriptome | Genomic and Transcriptomic Analysis of Mutant Bacillus subtilis with Enhanced Nattokinase Production via ARTP Mutagenesis. | Guo L, Chen Y, He Z, Wang Z, Chen Q, Chen J, Oz F, Xu Z, Zeng M. | Foods | 10.3390/foods14050898 | 2025 | |
| Enhancing Protease and Amylase Activities in Bacillus licheniformis XS-4 for Traditional Soy Sauce Fermentation Using ARTP Mutagenesis. | Zhang A, Ma Y, Deng Y, Zhou Z, Cao Y, Yang B, Bai J, Sun Q. | Foods | 10.3390/foods12122381 | 2023 | | |
| Enzymology | Aryl-alcohol oxidases: catalysis, diversity, structure-function and emerging biotechnological applications. | Cinca-Fernando P, Vazquez-Rodriguez A, Mangas-Sanchez J, Ferreira P. | Appl Microbiol Biotechnol | 10.1007/s00253-025-13538-7 | 2025 | |
| Antifungal Natural Products Originating from Endophytic and Rhizospheric Microbes Isolated from Coastal Vegetation. | Jayaweera SLD, Van TTH, Dias DA. | J Xenobiot | 10.3390/jox15010032 | 2025 | | |
| Metabolism | Bioactivity-HiTES Unveils Cryptic Antibiotics Encoded in Actinomycete Bacteria. | Moon K, Xu F, Zhang C, Seyedsayamdost MR. | ACS Chem Biol | 10.1021/acschembio.9b00049 | 2019 | |
| Enzymology | Isolation and characterization of Streptomyces hiroshimensis strain TI-C3 with anti-tyrosinase activity. | Chang TS, Tseng M, Ding HY, Shou-Ku Tai S. | J Cosmet Sci | 10.1111/j.1468-2494.2008.00446_3.x | 2008 | |
| Genetics | Whole genome analysis of Streptomyces sp. RerS4, a Rehmannia glutinosa rhizosphere microbe producing a new lipopeptide. | He H, Huang J, Zhao Z, Du P, Li J, Xin J, Xu H, Feng W, Zheng X. | Heliyon | 10.1016/j.heliyon.2023.e19543 | 2023 | |
| Metabolism | The correlations between TCA-glyoxalate metabolite and antibiotic production of Streptomyces sp. M4018 grown in glycerol, glucose, and starch mediums. | Tarhan L, Kayali HA, Sazak A, Sahin N. | Appl Biochem Biotechnol | 10.1007/s12010-010-9137-3 | 2011 | |
| Miramides A-D: Identification of Detoxin-like Depsipeptides after Heterologous Expression of a Hybrid NRPS-PKS Gene Cluster from Streptomyces mirabilis Lu17588. | Paulus C, Myronovskyi M, Zapp J, Rodriguez Estevez M, Lopatniuk M, Rosenkranzer B, Palusczak A, Luzhetskyy A. | Microorganisms | 10.3390/microorganisms10091752 | 2022 | | |
| Small molecule inducers of actinobacteria natural product biosynthesis. | Alwali AY, Parkinson EI. | J Ind Microbiol Biotechnol | 10.1093/jimb/kuad019 | 2023 | | |
| Phylogeny | Culturable Endophytes Diversity Isolated from Paeonia ostii and the Genetic Basis for Their Bioactivity. | Yang RX, Zhang SW, Xue D, Xuan JH, Zhang YB, Peng BB. | Pol J Microbiol | 10.21307/pjm-2018-052 | 2018 | |
| Enantioselective sulfoxidation using Streptomyces glaucescens GLA.0. | Salama S, Dishisha T, Habib MH, Abdelazem AZ, Bakeer W, Abdel-Latif M, Gaber Y. | RSC Adv | 10.1039/d0ra05838f | 2020 | | |
| Discovery of Three 22-Membered Macrolides by Deciphering the Streamlined Genome of Mangrove-Derived Streptomyces sp. HM190. | Ye Y, Anwar N, Mao X, Wu S, Yan C, Zhao Z, Zhang R, Nie Y, Zhang J, Wang J, Wu M. | Front Microbiol | 10.3389/fmicb.2020.01464 | 2020 | | |
| Recent Approaches for Downplaying Antibiotic Resistance: Molecular Mechanisms. | Ahmed S, Ahmed MZ, Rafique S, Almasoudi SE, Shah M, Jalil NAC, Ojha SC. | Biomed Res Int | 10.1155/2023/5250040 | 2023 | | |
| Pathogenicity | Selective suppression by prodigiosin of the mitogenic response of murine splenocytes. | Nakamura A, Nagai K, Ando K, Tamura G. | J Antibiot (Tokyo) | 10.7164/antibiotics.39.1155 | 1986 | |
| Enzymology | Detection, distribution, and organohalogen compound discovery implications of the reduced flavin adenine dinucleotide-dependent halogenase gene in major filamentous actinomycete taxonomic groups. | Gao P, Huang Y. | Appl Environ Microbiol | 10.1128/aem.02958-08 | 2009 | |
| Enzymology | A novel protein with alkaline phosphatase and protease inhibitor activities in Streptomyces hiroshimensis. | Nitta M, Goto M, Shibuya N, Okawa Y | Biol Pharm Bull | 10.1248/bpb.25.833 | 2002 | |
| Phylogeny | Taxonomic re-evaluation of whorl-forming Streptomyces (formerly Streptoverticillium) species by using phenotypes, DNA-DNA hybridization and sequences of gyrB, and proposal of Streptomyces luteireticuli (ex Katoh and Arai 1957) corrig., sp. nov., nom. rev. | Hatano K, Nishii T, Kasai H. | Int J Syst Evol Microbiol | 10.1099/ijs.0.02238-0 | 2003 | |
| Phylogeny | Streptomyces zagrosensis sp. nov., isolated from soil. | Mohammadipanah F, Hamedi J, Sproer C, Rohde M, Montero-Calasanz MDC, Klenk HP | Int J Syst Evol Microbiol | 10.1099/ijs.0.064527-0 | 2014 | |
| Phylogeny | Polyphasic classification of the gifted natural product producer Streptomyces roseifaciens sp. nov. | van der Aart LT, Nouioui I, Kloosterman A, Igual JM, Willemse J, Goodfellow M, van Wezel GP | Int J Syst Evol Microbiol | 10.1099/ijsem.0.003215 | 2019 | |
| Phylogeny | Streptomyces gamaensis sp. nov., a novel actinomycete with antifungal activity isolated from soil in Gama, Chad. | Zhao S, Ye L, Liu C, Abagana AY, Zheng W, Sun P, Li J, Xiang W, Wang X | Antonie Van Leeuwenhoek | 10.1007/s10482-016-0816-0 | 2016 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive15293.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
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