Mycobacterium abscessus subsp. massiliense (DSM 45103, CCUG 48898, CIP 108297)

Name: Mycobacterium abscessus subsp. massiliense (DSM 45103, CCUG 48898, CIP 108297)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 8546

Type strain

Culture col. no. DSM 45103 CCUG 48898 CIP 108297 KCTC 19086 JCM 15300 2 more

NCBI tax ID(s) 1962118

Special Collections DSMZ CCUG JCM KCTC CIP

History DSMZ <- CCUG <- M. Drancourt, Timone, Marseille JCM <-- CCUG 48898 <-- M. Drancourt. KCTC <- CCUG <- M Drancourt, Timone, Marseille, France 12 Mar 2004 CIP <- 2004, M. Drancourt, Timone Hosp., Marseille, France: strain LB, Mycobacterium massiliense

Links

Mycobacterium abscessus subsp. massiliense DSM 45103 is a microaerophile, Gram-positive human pathogen that was isolated from human sputum and bronchial alveolar lavage of 50 year old woman.

Gram-positive microaerophile human pathogen genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 134242

CCUG 48898,CIP 108297,KCTC 19086,DSM 45103,JCM 15300

@ref 20215

Last LPSN update 2026-05-29 08:26:53

Domain Bacteria

Phylum Actinomycetota

Class Actinomycetes

Order Mycobacteriales

Family Mycobacteriaceae

Genus Mycobacterium

Species Mycobacterium abscessus subsp. massiliense

Full scientific name Mycobacterium abscessus subsp. massiliense (Adékambi et al. 2006) Tortoli et al. 2016

Synonyms (2)

Mycobacteroides abscessus subsp. massiliense
Mycobacterium massiliense

BacDive ID	Other strains from **Mycobacterium abscessus subsp. massiliense** (2)	Type strain
169568	M. abscessus subsp. massiliense 19005109, DSM 113267
169569	M. abscessus subsp. massiliense 20004644, DSM 113268

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Confidence
67771	positive
115979	positive	rod-shaped
125438			92

Colony morphology

@ref	Incubation period	Hemolysis ability
58389	2-3 days
115979		1

Multimedia

@ref:	12345
multimedia content:	DSM_45103-1.jpg
multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_45103-1.jpg
intellectual property rights:	© Leibniz-Institut DSMZ
manual_annotation:	1

@ref:	12345
multimedia content:	DSM_45103-2.jpg
multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_45103-2.jpg
intellectual property rights:	© Leibniz-Institut DSMZ
manual_annotation:	1

@ref:	12345
multimedia content:	DSM_45103-3.jpg
multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_45103-3.jpg
intellectual property rights:	© Leibniz-Institut DSMZ
manual_annotation:	1

@ref:	12345
multimedia content:	DSM_45103-5.jpg
multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_45103-5.jpg
intellectual property rights:	© Leibniz-Institut DSMZ
manual_annotation:	1

@ref:	12345
multimedia content:	DSM_45103.jpg
multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_45103.jpg
caption:	Medium 645 37°C
intellectual property rights:	© Leibniz-Institut DSMZ
manual_annotation:	1

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
12345	MIDDLEBROOK MEDIUM (DSMZ Medium 645)	Medium recipe at MediaDive	Name: MIDDLEBROOK MEDIUM (DSMZ Medium 645) Composition: Bacto Middlebrook 7H10 agar 20.9945 g/l Glycerol Distilled water
115979	CIP Medium 45	Medium recipe at CIP
115979	CIP Medium 55	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
12345	positive	growth	37
58389	positive	growth	37
67770	positive	growth	37
67771	positive	growth	37

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
58389	microaerophile
67771	aerobe
115979	obligate aerobe
125439	obligate aerobe	94.599

Spore formation

@ref	Spore formation	Confidence
125439		96.789

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
115979	17632 ChEBI	nitrate	-	reduction
115979	16301 ChEBI	nitrite	-	reduction

Metabolite production

@ref	Chebi-ID	Metabolite	Production
115979	35581 ChEBI	indole

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
115979	alcohol dehydrogenase	-	1.1.1.1
68382	alkaline phosphatase	-	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68382	beta-galactosidase	-	3.2.1.23	from API zym
68382	beta-glucosidase	-	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
115979	catalase	+	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
115979	lysine decarboxylase	-	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
115979	ornithine decarboxylase	-	4.1.1.17
115979	oxidase	-
68382	trypsin	-	3.4.21.4	from API zym
115979	urease	-	3.5.1.5
68382	valine arylamidase	-		from API zym

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
115979	-	-	+	+	-	+	-	-	-	-	+	+	-	-	-	+	-	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Host	#Human	#Female
#Host Body Product	#Oral cavity and Airways	#Bronchial wash
#Host Body Product	#Fluids	#Sputum

Isolation

@ref	Sample type	Host species	Geographic location	Country	Country ISO 3 Code	Continent	Isolation date
12345	human sputum and bronchial alveolar lavage of 50 year old woman	Homo sapiens		France	FRA	Europe
58389	Human sputum and bronchial alveolar lavage,50y.w.	Homo sapiens	Marseille	France	FRA	Europe
67770	Sputum of a patient with hemoptoic pneumonia	Homo sapiens
67771	From Human sputum and bronchial alveolar lavage, 50y.w.	Homo sapiens	Marseille	France	FRA	Europe
115979	Human, Sputum	Homo sapiens	Marseille	France	FRA	Europe	2001

Taxonmaps

69479

Global distribution of 16S sequence AY593980 (>99% sequence identity) for Mycobacteroides from Microbeatlas

Aquatic Samples	6199
Soil Samples	7046
Animal Samples	7007
Plant Samples	1742
Total Samples	21994

Interaction and safety

Risk assessment

@ref	Pathogenicity human	Pathogenicity animal	Biosafety level	Biosafety level comment
12345			2	Risk group (German classification) According to TRBA 466
115979			2	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM49726v2 assembly for Mycobacteroides abscessus subsp. massiliense CCUG 48898 = JCM 15300	complete	GCA_000497265	1001714.4	2956067641	1001714	98.78
67770	ASM23905v2 assembly for Mycobacteroides abscessus subsp. massiliense CCUG 48898 = JCM 15300	contig	GCA_000239055	1001714.3	2526164611	1001714	75.28
67770	ASM208637v1 assembly for Mycobacteroides abscessus subsp. massiliense CCUG 48898	contig	GCA_002086375	1962118.3	8110856292	1962118	74
67770	ASM27066v1 assembly for Mycobacteroides abscessus subsp. massiliense CCUG 48898 = JCM 15300	contig	GCA_000270665	1001714.6	2531839070	1001714	73.28
66792	ASM179262v1 assembly for Mycobacteroides abscessus subsp. massiliense CIP 108297	contig	GCA_001792625	319705.17	8112313327	1962118	63.04

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Mycobacterium massiliense 16S-23S ribosomal RNA intergenic spacer, partial sequence	AY593978	258	319705
20218	Mycobacterium massiliense strain CIP 108297 16S ribosomal RNA gene, partial sequence	EU191912	457	319705
12345	Mycobacterium abscessus subsp. bolletii strain CCUG 48898 16S ribosomal RNA gene, partial sequence	AY593980	1481	1962118
67770	Mycobacterium abscessus subsp. bolletii gene for 16S ribosomal RNA, partial sequence, strain: JCM 15300	AB548602	1468	1001714

GC content

@ref	GC-content (mol%)	Method
12345	64.09	sequence analysis
67770	64.1	genome sequence analysis
67770	62-68	high performance liquid chromatography (HPLC)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: ASM49726v2 assembly for Mycobacteroides abscessus subsp. massiliense CCUG 48898 = JCM 15300
BV-BRC: 1001714.4

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	94.60	no
125439	gram_stain	BacteriaNetⓘ	positive	58.62	no
125439	motility	BacteriaNetⓘ	yes	41.16	no
125439	spore_formation	BacteriaNetⓘ	no	96.79	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Mycobacteroides abscessus subsp. massiliense CCUG 48898 = JCM 15300 JCM 15300
NCBI: GCA_000497265.2

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	89.30	no
125438	anaerobic	anaerobicⓘ	no	96.58	no
125438	aerobic	aerobicⓘ	yes	87.57	no
125438	spore-forming	spore-formingⓘ	no	63.82	no
125438	thermophilic	thermophileⓘ	no	97.00	yes
125438	flagellated	motile2+ⓘ	no	92.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	In Vitro Activity of the Sudapyridine (WX-081) against Non-Tuberculous Mycobacteria Isolated in Beijing, China.	Zhu R, Shang Y, Chen S, Xiao H, Ren R, Wang F, Xue Y, Li L, Li Y, Chu N, Huang H.	Microbiol Spectr	10.1128/spectrum.01372-22	2022
	Molecular longitudinal tracking of Mycobacterium abscessus spp. during chronic infection of the human lung.	Kreutzfeldt KM, McAdam PR, Claxton P, Holmes A, Seagar AL, Laurenson IF, Fitzgerald JR.	PLoS One	10.1371/journal.pone.0063237	2013
Phylogeny	Phylogenomics and Comparative Genomic Studies Robustly Support Division of the Genus Mycobacterium into an Emended Genus Mycobacterium and Four Novel Genera.	Gupta RS, Lo B, Son J.	Front Microbiol	10.3389/fmicb.2018.00067	2018
Genetics	Genomic-enabled classification of three Mycobacteroides abscessus subspecies and an effective subspecies-specific identification method.	Yu Z, Wang R.	J Clin Microbiol	10.1128/jcm.00697-25	2025
	Aortic endograft infection by Mycobacterium abscessus subsp. massiliense with acquired clarithromycin resistance: a case report.	Akiyama Y, Iwamoto N, Kamada K, Yoshida A, Osugi A, Mitarai S, Suzuki T, Yamamoto K, Nagashima M, Horai T, Ohmagari N.	BMC Infect Dis	10.1186/s12879-023-08702-1	2023
	A potent phenylalkylamine disrupts mycobacterial membrane bioenergetics and augments bactericidal activity of bedaquiline.	Phua ZY, Li M, Ali A, Cheong CCS, Goh KJ, Seto MYK, Ng ASY, Sarathy JP, Goh BC, Go ML, Chui WK, Dick T, Lam Y.	iScience	10.1016/j.isci.2025.112915	2025
	Broad-Spectrum In Vitro Activity of Nalpha-Aroyl-N-Aryl-Phenylalanine Amides against Non-Tuberculous Mycobacteria and Comparative Analysis of RNA Polymerases.	Lang M, Ganapathy US, Abdelaziz R, Dick T, Richter A.	Antibiotics (Basel)	10.3390/antibiotics13050404	2024
Genetics	Transposon-sequencing across multiple Mycobacterium abscessus isolates reveals significant functional genomic diversity among strains.	Akusobi C, Choudhery S, Benghomari BS, Wolf ID, Singhvi S, Ioerger TR, Rubin EJ.	mBio	10.1128/mbio.03376-24	2025
	Toward a Bactericidal Oral Drug Combination for the Treatment of Mycobacterium abscessus Lung Disease.	Sarathy JP, Xie M, Wong CF, Negatu DA, Rodriguez S, Zimmerman MD, Jimenez DC, Alshiraihi IM, Gonzalez-Juarrero M, Dartois V, Dick T.	ACS Infect Dis	10.1021/acsinfecdis.4c00948	2025
	Carbonyl Cyanide 3-Chlorophenylhydrazone (CCCP) Exhibits Direct Antibacterial Activity Against Mycobacterium abscessus.	Chen S, Teng T, Zhang Z, Shang Y, Xiao H, Jiang G, Wang F, Jia J, Dong L, Zhao L, Chu N, Huang H.	Infect Drug Resist	10.2147/idr.s303113	2021
	Mycobacterium tuberculosis DprE1 Inhibitor OPC-167832 Is Active against Mycobacterium abscessus In Vitro.	Sarathy JP, Zimmerman MD, Gengenbacher M, Dartois V, Dick T.	Antimicrob Agents Chemother	10.1128/aac.01237-22	2022
	Disulfiram Is Effective against Drug-Resistant Mycobacterium abscessus in a Zebrafish Embryo Infection Model.	Winters CG, Basnet RM, Faasuamalie PE, Shallom SJ, Zelazny AM, Gupta S, Olivier KN.	Antimicrob Agents Chemother	10.1128/aac.00539-22	2022
Pathogenicity	TBAJ-876, a 3,5-Dialkoxypyridine Analogue of Bedaquiline, Is Active against Mycobacterium abscessus.	Sarathy JP, Ganapathy US, Zimmerman MD, Dartois V, Gengenbacher M, Dick T.	Antimicrob Agents Chemother	10.1128/aac.02404-19	2020
	Rifabutin Suppresses Inducible Clarithromycin Resistance in Mycobacterium abscessus by Blocking Induction of whiB7 and erm41.	Aziz DB, Go ML, Dick T.	Antibiotics (Basel)	10.3390/antibiotics9020072	2020
	Genomic epidemiology of Mycobacterium abscessus in a Canadian cystic fibrosis centre.	Waglechner N, Tullis E, Stephenson AL, Waters V, McIntosh F, Ma J, Jamieson FB, Behr MA, Batt J, Lee RS.	Sci Rep	10.1038/s41598-022-19666-8	2022
Pathogenicity	Rifabutin Is Active against Mycobacterium abscessus Complex.	Aziz DB, Low JL, Wu ML, Gengenbacher M, Teo JWP, Dartois V, Dick T.	Antimicrob Agents Chemother	10.1128/aac.00155-17	2017
	Complete Genome Sequence of Mycobacterium abscessus subsp. bolletii.	Caverly LJ, Spilker T, LiPuma JJ.	Genome Announc	10.1128/genomea.00543-16	2016
Phylogeny	Phylogenomics of Brazilian epidemic isolates of Mycobacterium abscessus subsp. bolletii reveals relationships of global outbreak strains.	Davidson RM, Hasan NA, de Moura VC, Duarte RS, Jackson M, Strong M.	Infect Genet Evol	10.1016/j.meegid.2013.09.012	2013
	Teicoplanin - Tigecycline Combination Shows Synergy Against Mycobacterium abscessus.	Aziz DB, Teo JWP, Dartois V, Dick T.	Front Microbiol	10.3389/fmicb.2018.00932	2018
	Increased Virulence of Outer Membrane Porin Mutants of Mycobacterium abscessus.	de Moura VCN, Verma D, Everall I, Brown KP, Belardinelli JM, Shanley C, Stapleton M, Parkhill J, Floto RA, Ordway DJ, Jackson M.	Front Microbiol	10.3389/fmicb.2021.706207	2021
	A Two-Step Real-Time PCR Method To Identify Mycobacterium tuberculosis Infections and Six Dominant Nontuberculous Mycobacterial Infections from Clinical Specimens.	Park J, Kwak N, Chae JC, Yoon EJ, Jeong SH.	Microbiol Spectr	10.1128/spectrum.01606-23	2023
Phylogeny	New rapid scheme for distinguishing the subspecies of the Mycobacterium abscessus group and identifying Mycobacterium massiliense isolates with inducible clarithromycin resistance.	Shallom SJ, Gardina PJ, Myers TG, Sebastian Y, Conville P, Calhoun LB, Tettelin H, Olivier KN, Uzel G, Sampaio EP, Holland SM, Zelazny AM.	J Clin Microbiol	10.1128/jcm.01132-13	2013
	Genome Sequence of an Epidemic Isolate of Mycobacterium abscessus subsp. bolletii from Rio de Janeiro, Brazil.	Davidson RM, Reynolds PR, Farias-Hesson E, Duarte RS, Jackson M, Strong M.	Genome Announc	10.1128/genomea.00617-13	2013
Genetics	GenoType NTM-DR Performance Evaluation for Identification of Mycobacterium avium Complex and Mycobacterium abscessus and Determination of Clarithromycin and Amikacin Resistance.	Huh HJ, Kim SY, Shim HJ, Kim DH, Yoo IY, Kang OK, Ki CS, Shin SY, Jhun BW, Shin SJ, Daley CL, Koh WJ, Lee NY.	J Clin Microbiol	10.1128/jcm.00516-19	2019
Metabolism	Comprehensive Comparative Analysis of Cholesterol Catabolic Genes/Proteins in Mycobacterial Species.	van Wyk R, van Wyk M, Mashele SS, Nelson DR, Syed K.	Int J Mol Sci	10.3390/ijms20051032	2019
	Inducible and Acquired Clarithromycin Resistance in the Mycobacterium abscessus Complex.	Rubio M, March F, Garrigo M, Moreno C, Espanol M, Coll P.	PLoS One	10.1371/journal.pone.0140166	2015
Phylogeny	Variation among human, veterinary and environmental Mycobacterium chelonae-abscessus complex isolates observed using core genome phylogenomic analysis, targeted gene comparison, and anti-microbial susceptibility patterns.	Fogelson SB, Camus AC, Lorenz WW, Vasireddy R, Vasireddy S, Smith T, Brown-Elliott BA, Wallace RJ, Hasan NA, Reischl U, Sanchez S.	PLoS One	10.1371/journal.pone.0214274	2019
Phylogeny	Phylogenetic analysis of Mycobacterium massiliense strains having recombinant rpoB gene laterally transferred from Mycobacterium abscessus.	Kim BJ, Kim GN, Kim BR, Shim TS, Kook YH, Kim BJ.	PLoS One	10.1371/journal.pone.0179237	2017
Genetics	MabsBase: a Mycobacterium abscessus genome and annotation database.	Heydari H, Wee WY, Lokanathan N, Hari R, Mohamed Yusoff A, Beh CY, Yazdi AH, Wong GJ, Ngeow YF, Choo SW.	PLoS One	10.1371/journal.pone.0062443	2013
	beta-Lactam Combinations That Exhibit Synergy against Mycobacteroides abscessus Clinical Isolates.	Story-Roller E, Galanis C, Lamichhane G.	Antimicrob Agents Chemother	10.1128/aac.02545-20	2021
Phylogeny	Diversity of pulsed-field gel electrophoresis patterns of Mycobacterium abscessus type 2 clinical isolates.	Matsumoto CK, Chimara E, Bombarda S, Duarte RS, Leao SC.	J Clin Microbiol	10.1128/jcm.01665-10	2011
Genetics	Genome analysis reveals three genomospecies in Mycobacterium abscessus.	Sassi M, Drancourt M.	BMC Genomics	10.1186/1471-2164-15-359	2014
Phylogeny	Multilocus sequence typing scheme versus pulsed-field gel electrophoresis for typing Mycobacterium abscessus isolates.	Machado GE, Matsumoto CK, Chimara E, Duarte Rda S, de Freitas D, Palaci M, Hadad DJ, Lima KV, Lopes ML, Ramos JP, Campos CE, Caldas PC, Heym B, Leao SC.	J Clin Microbiol	10.1128/jcm.00688-14	2014
	The detection and sequencing of a broad-host-range conjugative IncP-1beta plasmid in an epidemic strain of Mycobacterium abscessus subsp. bolletii.	Leao SC, Matsumoto CK, Carneiro A, Ramos RT, Nogueira CL, Lima JD, Lima KV, Lopes ML, Schneider H, Azevedo VA, da Costa da Silva A.	PLoS One	10.1371/journal.pone.0060746	2013
Phylogeny	New Mycobacteroides abscessus subsp. massiliense strains with recombinant hsp65 gene laterally transferred from Mycobacteroides abscessus subsp. abscessus: Potential for misidentification of M. abscessus strains with the hsp65-based method.	Kim BJ, Kim GN, Kim BR, Shim TS, Kook YH, Kim BJ.	PLoS One	10.1371/journal.pone.0220312	2019
Pathogenicity	Multidrug-resistant nontuberculous mycobacteria isolated from cystic fibrosis patients.	Candido PH, Nunes Lde S, Marques EA, Folescu TW, Coelho FS, de Moura VC, da Silva MG, Gomes KM, Lourenco MC, Aguiar FS, Chitolina F, Armstrong DT, Leao SC, Neves FP, Mello FC, Duarte RS.	J Clin Microbiol	10.1128/jcm.00549-14	2014
Genetics	Genomic reconnaissance of clinical isolates of emerging human pathogen Mycobacterium abscessus reveals high evolutionary potential.	Choo SW, Wee WY, Ngeow YF, Mitchell W, Tan JL, Wong GJ, Zhao Y, Xiao J.	Sci Rep	10.1038/srep04061	2014
Enzymology	An enoyl-ACP reductase inhibitor, NITD-916, expresses anti-Mycobacterium abscessus activity.	Jia Y, Fan J, Tan Z, Li A, He S, Lin Y, Li J, Zhang Z, Li B, Chu H.	Antimicrob Agents Chemother	10.1128/aac.00249-25	2025
	TBAJ-587, a novel diarylquinoline, is active against Mycobacterium abscessus.	Fan J, Tan Z, He S, Li A, Jia Y, Li J, Zhang Z, Li B, Chu H.	Antimicrob Agents Chemother	10.1128/aac.00945-24	2024
	A Novel Leucyl-tRNA Synthetase Inhibitor, MRX-6038, Expresses Anti-Mycobacterium abscessus Activity In Vitro and In Vivo.	Wu W, He S, Li A, Guo Q, Tan Z, Liu S, Wang X, Zhang Z, Li B, Chu H.	Antimicrob Agents Chemother	10.1128/aac.00601-22	2022
	Analysis of Phenotypic and Genotypic Susceptibility to Clarithromycin and Amikacin of Mycobacterium abscessus Complex Strains Isolated from Cystic Fibrosis Patients.	Cao Yao JC, Navas Mendez J, Tortola Fernandez MT.	Microorganisms	10.3390/microorganisms11122897	2023
	Sitafloxacin Expresses Potent Anti-Mycobacterium abscessus Activity.	He S, Guo Q, Zhao L, Xu L, Fan J, Wu W, Zhang Z, Li B, Chu H.	Front Microbiol	10.3389/fmicb.2021.779531	2021
	Omadacycline, Eravacycline, and Tigecycline Express Anti-Mycobacterium abscessus Activity In Vitro.	Li A, He S, Li J, Zhang Z, Li B, Chu H.	Microbiol Spectr	10.1128/spectrum.00718-23	2023
	2-Aminoimidazoles Inhibit Mycobacterium abscessus Biofilms in a Zinc-Dependent Manner.	Belardinelli JM, Li W, Martin KH, Zeiler MJ, Lian E, Avanzi C, Wiersma CJ, Nguyen TV, Angala B, de Moura VCN, Jones V, Borlee BR, Melander C, Jackson M.	Int J Mol Sci	10.3390/ijms23062950	2022
	Toward better cures for Mycobacterium abscessus lung disease.	Dartois V, Dick T.	Clin Microbiol Rev	10.1128/cmr.00080-23	2024
	A laboratory perspective on Mycobacterium abscessus biofilm culture, characterization and drug activity testing.	Meliefste HM, Mudde SE, Ammerman NC, de Steenwinkel JEM, Bax HI.	Front Microbiol	10.3389/fmicb.2024.1392606	2024
	Preclinical murine models for the testing of antimicrobials against Mycobacterium abscessus pulmonary infections: Current practices and recommendations.	Dartois V, Bonfield TL, Boyce JP, Daley CL, Dick T, Gonzalez-Juarrero M, Gupta S, Kramnik I, Lamichhane G, Laughon BE, Lore NI, Malcolm KC, Olivier KN, Tuggle KL, Jackson M.	Tuberculosis (Edinb)	10.1016/j.tube.2024.102503	2024
	Mycobacterium abscessus resists the innate cellular response by surviving cell lysis of infected phagocytes.	Toure H, Galindo LA, Lagune M, Glatigny S, Waterhouse RM, Guenal I, Herrmann JL, Girard-Misguich F, Szuplewski S.	PLoS Pathog	10.1371/journal.ppat.1011257	2023
Pathogenicity	Disinfectant Susceptibility Profiling of Glutaraldehyde-Resistant Nontuberculous Mycobacteria.	Burgess W, Margolis A, Gibbs S, Duarte RS, Jackson M.	Infect Control Hosp Epidemiol	10.1017/ice.2017.75	2017
	Comparing the Utilities of Different Multilocus Sequence Typing Schemes for Identifying Outbreak Strains of Mycobacterium abscessus subsp. massiliense.	Cheng A, Sun HY, Tsai YT, Chang SY, Wu UI, Hsueh PR, Sheng WH, Chen YC, Chang SC.	J Clin Microbiol	10.1128/jcm.01304-19	2019
Phylogeny	Classification algorithm for subspecies identification within the Mycobacterium abscessus species, based on matrix-assisted laser desorption ionization-time of flight mass spectrometry.	Fangous MS, Mougari F, Gouriou S, Calvez E, Raskine L, Cambau E, Payan C, Hery-Arnaud G.	J Clin Microbiol	10.1128/jcm.00788-14	2014
Genetics	Genome-wide mosaicism within Mycobacterium abscessus: evolutionary and epidemiological implications.	Sapriel G, Konjek J, Orgeur M, Bouri L, Frezal L, Roux AL, Dumas E, Brosch R, Bouchier C, Brisse S, Vandenbogaert M, Thiberge JM, Caro V, Ngeow YF, Tan JL, Herrmann JL, Gaillard JL, Heym B, Wirth T.	BMC Genomics	10.1186/s12864-016-2448-1	2016
	MmpL3 as a Target for the Treatment of Drug-Resistant Nontuberculous Mycobacterial Infections.	Li W, Yazidi A, Pandya AN, Hegde P, Tong W, Calado Nogueira de Moura V, North EJ, Sygusch J, Jackson M.	Front Microbiol	10.3389/fmicb.2018.01547	2018
Enzymology	Sacroiliitis secondary to catheter-related bacteremia due to Mycobacterium abscessus (sensu stricto).	Laurens C, Hery-Arnaud G, Chiron R, Oziol E, Jean-Pierre H, Bouzinbi N, Vande Perre P, Banuls AL, Godreuil S.	Ann Clin Microbiol Antimicrob	10.1186/1476-0711-13-9	2014
	Increased survival and proliferation of the epidemic strain Mycobacterium abscessus subsp. massiliense CRM0019 in alveolar epithelial cells.	Ribeiro GM, Matsumoto CK, Real F, Teixeira D, Duarte RS, Mortara RA, Leao SC, de Souza Carvalho-Wodarz C.	BMC Microbiol	10.1186/s12866-017-1102-7	2017
Enzymology	Mycobacterium massiliense bacteremia as a consequence of M. massiliense pneumonia in a patient with acute lymphoblastic leukemia.	Kim J, Park JS, Jeong YS, Kim DY, Sung H, Kim MN.	J Clin Microbiol	10.1128/jcm.03543-13	2014
Enzymology	Development of a One-Step Multiplex PCR Assay for Differential Detection of Major Mycobacterium Species.	Chae H, Han SJ, Kim SY, Ki CS, Huh HJ, Yong D, Koh WJ, Shin SJ.	J Clin Microbiol	10.1128/jcm.00549-17	2017
Phylogeny	Molecular characterization of Mycobacterium massiliense and Mycobacterium bolletii in isolates collected from outbreaks of infections after laparoscopic surgeries and cosmetic procedures.	Viana-Niero C, Lima KV, Lopes ML, Rabello MC, Marsola LR, Brilhante VC, Durham AM, Leao SC.	J Clin Microbiol	10.1128/jcm.02052-07	2008
Phylogeny	Cohort study of molecular identification and typing of Mycobacterium abscessus, Mycobacterium massiliense, and Mycobacterium bolletii.	Zelazny AM, Root JM, Shea YR, Colombo RE, Shamputa IC, Stock F, Conlan S, McNulty S, Brown-Elliott BA, Wallace RJ, Olivier KN, Holland SM, Sampaio EP.	J Clin Microbiol	10.1128/jcm.01688-08	2009
Pathogenicity	Assessment of clarithromycin susceptibility in strains belonging to the Mycobacterium abscessus group by erm(41) and rrl sequencing.	Bastian S, Veziris N, Roux AL, Brossier F, Gaillard JL, Jarlier V, Cambau E.	Antimicrob Agents Chemother	10.1128/aac.00861-10	2011
Enzymology	Outbreak of Mycobacterium massiliense infection associated with intramuscular injections.	Kim HY, Yun YJ, Park CG, Lee DH, Cho YK, Park BJ, Joo SI, Kim EC, Hur YJ, Kim BJ, Kook YH.	J Clin Microbiol	10.1128/jcm.00608-07	2007
Phylogeny	Proportions of Mycobacterium massiliense and Mycobacterium bolletii strains among Korean Mycobacterium chelonae-Mycobacterium abscessus group isolates.	Kim HY, Kook Y, Yun YJ, Park CG, Lee NY, Shim TS, Kim BJ, Kook YH.	J Clin Microbiol	10.1128/jcm.00319-08	2008
Metabolism	Mycobacterium massiliense Induces Macrophage Extracellular Traps with Facilitating Bacterial Growth.	Je S, Quan H, Yoon Y, Na Y, Kim BJ, Seok SH.	PLoS One	10.1371/journal.pone.0155685	2016
Phylogeny	Rapid identification of mycobacterial whole cells in solid and liquid culture media by matrix-assisted laser desorption ionization-time of flight mass spectrometry.	Lotz A, Ferroni A, Beretti JL, Dauphin B, Carbonnelle E, Guet-Revillet H, Veziris N, Heym B, Jarlier V, Gaillard JL, Pierre-Audigier C, Frapy E, Berche P, Nassif X, Bille E.	J Clin Microbiol	10.1128/jcm.01397-10	2010
Enzymology	Epidemic of postsurgical infections caused by Mycobacterium massiliense.	Duarte RS, Lourenco MC, Fonseca Lde S, Leao SC, Amorim Ede L, Rocha IL, Coelho FS, Viana-Niero C, Gomes KM, da Silva MG, Lorena NS, Pitombo MB, Ferreira RM, Garcia MH, de Oliveira GP, Lupi O, Vilaca BR, Serradas LR, Chebabo A, Marques EA, Teixeira LM, Dalcolmo M, Senna SG, Sampaio JL.	J Clin Microbiol	10.1128/jcm.00027-09	2009
Metabolism	Discovery of a novel hsp65 genotype within Mycobacterium massiliense associated with the rough colony morphology.	Kim BJ, Yi SY, Shim TS, Do SY, Yu HK, Park YG, Kook YH, Kim BJ.	PLoS One	10.1371/journal.pone.0038420	2012
Phylogeny	Development of a peptide nucleic acid-based multiprobe real-time PCR method targeting the hsp65 gene for differentiation among Mycobacterium abscessus strains.	Kim K, Kim BJ, Shim TS, Hong SH, Kook YH, Kim BJ.	J Clin Microbiol	10.1128/jcm.03424-14	2015
Genetics	Potential Cross-Transmission of Mycobacterium abscessus among Non-Cystic Fibrosis Patients at a Tertiary Hospital in Japan.	Fujiwara K, Yoshida M, Murase Y, Aono A, Furuuchi K, Tanaka Y, Ohta K, Ato M, Mitarai S, Morimoto K.	Microbiol Spectr	10.1128/spectrum.00097-22	2022
	Delineating Mycobacterium abscessus population structure and transmission employing high-resolution core genome multilocus sequence typing.	Diricks M, Merker M, Wetzstein N, Kohl TA, Niemann S, Maurer FP.	Nat Commun	10.1038/s41467-022-32122-5	2022
Pathogenicity	A novel DNA chromatography method to discriminate Mycobacterium abscessus subspecies and macrolide susceptibility.	Yoshida M, Sano S, Chien JY, Fukano H, Suzuki M, Asakura T, Morimoto K, Murase Y, Miyamoto S, Kurashima A, Hasegawa N, Hsueh PR, Mitarai S, Ato M, Hoshino Y.	EBioMedicine	10.1016/j.ebiom.2020.103187	2021
	Association between 16S rRNA gene mutations and susceptibility to amikacin in Mycobacterium avium Complex and Mycobacterium abscessus clinical isolates.	Kim SY, Kim DH, Moon SM, Song JY, Huh HJ, Lee NY, Shin SJ, Koh WJ, Jhun BW.	Sci Rep	10.1038/s41598-021-85721-5	2021
Pathogenicity	In Vitro Synergism of Rifabutin with Clarithromycin, Imipenem, and Tigecycline against the Mycobacterium abscessus Complex.	Cheng A, Tsai YT, Chang SY, Sun HY, Wu UI, Sheng WH, Chen YC, Chang SC.	Antimicrob Agents Chemother	10.1128/aac.02234-18	2019
Phylogeny	Emended description of Mycobacterium abscessus, Mycobacterium abscessus subsp. abscessus and Mycobacteriumabscessus subsp. bolletii and designation of Mycobacteriumabscessus subsp. massiliense comb. nov.	Tortoli E, Kohl TA, Brown-Elliott BA, Trovato A, Leao SC, Garcia MJ, Vasireddy S, Turenne CY, Griffith DE, Philley JV, Baldan R, Campana S, Cariani L, Colombo C, Taccetti G, Teri A, Niemann S, Wallace RJ Jr, Cirillo DM	Int J Syst Evol Microbiol	10.1099/ijsem.0.001376	2016
Genetics	Complete genome sequence and comparative genomic analysis of Mycobacterium massiliense JCM 15300 in the Mycobacterium abscessus group reveal a conserved genomic island MmGI-1 related to putative lipid metabolism.	Sekizuka T, Kai M, Nakanaga K, Nakata N, Kazumi Y, Maeda S, Makino M, Hoshino Y, Kuroda M	PLoS One	10.1371/journal.pone.0114848	2014
Genetics	Discrimination of Mycobacterium abscessus subsp. massiliense from Mycobacterium abscessus subsp. abscessus in clinical isolates by multiplex PCR.	Nakanaga K, Sekizuka T, Fukano H, Sakakibara Y, Takeuchi F, Wada S, Ishii N, Makino M, Kuroda M, Hoshino Y	J Clin Microbiol	10.1128/JCM.01327-13	2013
Genetics	Genomic insights into the emerging human pathogen Mycobacterium massiliense.	Tettelin H, Sampaio EP, Daugherty SC, Hine E, Riley DR, Sadzewicz L, Sengamalay N, Shefchek K, Su Q, Tallon LJ, Conville P, Olivier KN, Holland SM, Fraser CM, Zelazny AM	J Bacteriol	10.1128/JB.01200-12	2012
	Increased virulence of an epidemic strain of Mycobacterium massiliense in mice.	Shang S, Gibbs S, Henao-Tamayo M, Shanley CA, McDonnell G, Duarte RS, Ordway DJ, Jackson M	PLoS One	10.1371/journal.pone.0024726	2011
Transcriptome	Multilocus sequence analysis and rpoB sequencing of Mycobacterium abscessus (sensu lato) strains.	Macheras E, Roux AL, Bastian S, Leao SC, Palaci M, Sivadon-Tardy V, Gutierrez C, Richter E, Rusch-Gerdes S, Pfyffer G, Bodmer T, Cambau E, Gaillard JL, Heym B	J Clin Microbiol	10.1128/JCM.01274-10	2010
Genetics	The genome sequence of 'Mycobacterium massiliense' strain CIP 108297 suggests the independent taxonomic status of the Mycobacterium abscessus complex at the subspecies level.	Cho YJ, Yi H, Chun J, Cho SN, Daley CL, Koh WJ, Shin SJ	PLoS One	10.1371/journal.pone.0081560	2013
Phylogeny	Amoebal coculture of "Mycobacterium massiliense" sp. nov. from the sputum of a patient with hemoptoic pneumonia.	Adekambi T, Reynaud-Gaubert M, Greub G, Gevaudan MJ, La Scola B, Raoult D, Drancourt M	J Clin Microbiol	10.1128/JCM.42.12.5493-5501.2004	2004

References

#12345	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 45103
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#58389	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 48898
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#67771	Korean Collection for Type Cultures (KCTC) ; Curators of the KCTC;
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#115979	Collection of Institut Pasteur ; Curators of the CIP; CIP 108297
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Mycobacterium abscessus subsp. massiliense (DSM 45103, CCUG 48898, CIP 108297)

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