Mycobacterium tuberculosis BCGT is a prokaryote of the family Mycobacteriaceae.
| @ref 20215 |
|
|
| Domain Bacteria |
| Phylum Actinomycetota |
| Class Actinomycetes |
| Order Mycobacteriales |
| Family Mycobacteriaceae |
| Genus Mycobacterium |
| Species Mycobacterium tuberculosis |
| Full scientific name Mycobacterium tuberculosis (Zopf 1883) Lehmann and Neumann 1896 (Approved Lists 1980) |
| Synonyms (8) |
| @ref: | 11440 |
| multimedia content: | DSM_43990-1.jpg |
| multimedia.multimedia content: | https://www.dsmz.de/microorganisms/photos/DSM_43990-1.jpg |
| intellectual property rights: | © Leibniz-Institut DSMZ |
| manual_annotation: | 1 |
| @ref: | 11440 |
| multimedia content: | DSM_43990-2.jpg |
| multimedia.multimedia content: | https://www.dsmz.de/microorganisms/photos/DSM_43990-2.jpg |
| intellectual property rights: | © Leibniz-Institut DSMZ |
| manual_annotation: | 1 |
| @ref: | 11440 |
| multimedia content: | DSM_43990.jpg |
| multimedia.multimedia content: | https://www.dsmz.de/microorganisms/photos/DSM_43990.jpg |
| caption: | Medium 645 37°C |
| intellectual property rights: | © Leibniz-Institut DSMZ |
| manual_annotation: | 1 |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| S-Adenosylmethionine (SAM)-Dependent Methyltransferase MftM is Responsible for Methylation of the Redox Cofactor Mycofactocin. | Ellerhorst M, Barth SA, Graca AP, Al-Jammal WK, Pena-Ortiz L, Vilotijevic I, Lackner G. | ACS Chem Biol | 10.1021/acschembio.2c00659 | 2022 | ||
| Metabolism | Metabolic activity of mature biofilms of Mycobacterium tuberculosis and other non-tuberculous mycobacteria. | Solokhina A, Bruckner D, Bonkat G, Braissant O. | Sci Rep | 10.1038/s41598-017-10019-4 | 2017 | |
| Pathogenicity | Structure-Activity Relationship and Mode-Of-Action Studies Highlight 1-(4-Biphenylylmethyl)-1H-imidazole-Derived Small Molecules as Potent CYP121 Inhibitors. | Walter I, Adam S, Gentilini MV, Kany AM, Brengel C, Thomann A, Sparwasser T, Kohnke J, Hartmann RW. | ChemMedChem | 10.1002/cmdc.202100283 | 2021 | |
| Genetics | Population Structure of Mycobacterium bovis in Germany: a Long-Term Study Using Whole-Genome Sequencing Combined with Conventional Molecular Typing Methods. | Kohl TA, Kranzer K, Andres S, Wirth T, Niemann S, Moser I. | J Clin Microbiol | 10.1128/jcm.01573-20 | 2020 | |
| Metabolism | Effects of Halide Ions on the Carbamidocyclophane Biosynthesis in Nostoc sp. CAVN2. | Preisitsch M, Heiden SE, Beerbaum M, Niedermeyer TH, Schneefeld M, Herrmann J, Kumpfmuller J, Thurmer A, Neidhardt I, Wiesner C, Daniel R, Muller R, Bange FC, Schmieder P, Schweder T, Mundt S. | Mar Drugs | 10.3390/md14010021 | 2016 | |
| Metabolism | Mycobacterium bovis BCG Interferes with miR-3619-5p Control of Cathepsin S in the Process of Autophagy. | Pawar K, Sharbati J, Einspanier R, Sharbati S. | Front Cell Infect Microbiol | 10.3389/fcimb.2016.00027 | 2016 | |
| Region of difference 4 in alpine Mycobacterium caprae isolates indicates three variants. | Domogalla J, Prodinger WM, Blum H, Krebs S, Gellert S, Muller M, Neuendorf E, Sedlmaier F, Buttner M. | J Clin Microbiol | 10.1128/jcm.02966-12 | 2013 | ||
| Down regulated lncRNA MEG3 eliminates mycobacteria in macrophages via autophagy. | Pawar K, Hanisch C, Palma Vera SE, Einspanier R, Sharbati S. | Sci Rep | 10.1038/srep19416 | 2016 | ||
| Enzymology | Biochemical characterization of the maltokinase from Mycobacterium bovis BCG. | Mendes V, Maranha A, Lamosa P, da Costa MS, Empadinhas N. | BMC Biochem | 10.1186/1471-2091-11-21 | 2010 | |
| A comprehensive evaluation of a novel targeted-sequencing workflow for Mycobacterium species identification and anti-tuberculosis drug-resistance detection. | Ou X, Pei S, Li H, Qin Z, Anthony R, Wang J, Song Z, Xing R, Zhang L, Teng C, Xia H, Zhou Y, Song Y, Zheng Y, Wang S, Zhao B, Zhao Y. | Front Cell Infect Microbiol | 10.3389/fcimb.2025.1584237 | 2025 | ||
| Phylogeny | Three-reaction high-resolution melting assay for rapid differentiation of Mycobacterium tuberculosis complex members. | Landolt P, Stephan R, Stevens MJA, Scherrer S. | Microbiologyopen | 10.1002/mbo3.919 | 2019 | |
| BCG Substrains Change Their Outermost Surface as a Function of Growth Media. | Guallar-Garrido S, Alminana-Rapun F, Campo-Perez V, Torrents E, Luquin M, Julian E. | Vaccines (Basel) | 10.3390/vaccines10010040 | 2021 | ||
| Field Trial with Vaccine Candidates Against Bovine Tuberculosis Among Likely Infected Cattle in a Natural Transmission Setting. | Ferrara Muniz X, Garcia E, Blanco FC, Garbaccio S, Garro C, Zumarraga M, Dellagostin O, Trangoni M, Marfil MJ, Bianco MV, Abdala A, Revelli J, Bergamasco M, Soutullo A, Marini R, Rocha RV, Sanchez A, Bigi F, Canal AM, Eirin ME, Cataldi AA. | Vaccines (Basel) | 10.3390/vaccines12101173 | 2024 | ||
| Enzymology | Culture and molecular method for detection of Mycobacterium tuberculosis complex and Mycobacterium avium subsp. paratuberculosis in milk and dairy products. | Messelhausser U, Kampf P, Hormansdorfer S, Wagner B, Schalch B, Busch U, Holler C, Wallner P, Barth G, Rampp A. | Appl Environ Microbiol | 10.1128/aem.06322-11 | 2012 | |
| Epidemiological tracing of bovine tuberculosis in Switzerland, multilocus variable number of tandem repeat analysis of Mycobacterium bovis and Mycobacterium caprae. | Ghielmetti G, Scherrer S, Friedel U, Frei D, Suter D, Perler L, Wittenbrink MM. | PLoS One | 10.1371/journal.pone.0172474 | 2017 | ||
| Pathogenicity | CHEMICAL CHARACTERIZATION AND EVALUATION OF ANTIBACTERIAL, ANTIFUNGAL, ANTIMYCOBACTERIAL, AND CYTOTOXIC ACTIVITIES OF Talinum paniculatum. | Dos Reis LF, Cerdeira CD, De Paula BF, Silva JJ, Coelho LF, Silva MA, Marques VB, Chavasco JK, Alves-Da-Silva G. | Rev Inst Med Trop Sao Paulo | 10.1590/s0036-46652015000500005 | 2015 | |
| Bayesian Assessment of the Accuracy of a PCR-Based Rapid Diagnostic Test for Bovine Tuberculosis in Swine. | Barandiaran S, Perez Aguirreburualde MS, Marfil MJ, Martinez Vivot M, Aznar N, Zumarraga M, Perez AM. | Front Vet Sci | 10.3389/fvets.2019.00204 | 2019 | ||
| Synthesis and evaluation of a pyrazinoic acid prodrug in Mycobacterium tuberculosis. | Fernandes JP, Pavan FR, Leite CQ, Felli VM. | Saudi Pharm J | 10.1016/j.jsps.2013.12.005 | 2014 | ||
| Pathogenicity | Evaluation of antimicrobial and cytotoxic activities of plant extracts from southern Minas Gerais cerrado. | Chavasco JM, Prado E Feliphe BH, Cerdeira CD, Leandro FD, Coelho LF, Silva JJ, Chavasco JK, Dias AL. | Rev Inst Med Trop Sao Paulo | 10.1590/s0036-46652014000100002 | 2014 | |
| Development of a Recombinase Polymerase Amplification Assay for Rapid Detection of the Mycobacterium avium subsp. paratuberculosis. | Hansen S, Schafer J, Fechner K, Czerny CP, Abd El Wahed A. | PLoS One | 10.1371/journal.pone.0168733 | 2016 | ||
| Pulmonary tuberculosis due to Mycobacterium bovis subsp. caprae in captive Siberian tiger. | Lantos A, Niemann S, Mezosi L, Sos E, Erdelyi K, David S, Parsons LM, Kubica T, Rusch-Gerdes S, Somoskovi A. | Emerg Infect Dis | 10.3201/eid0911.030297 | 2003 | ||
| Pathogenicity | In vitro antimycobacterial activity of 5-chloropyrazinamide. | Cynamon MH, Speirs RJ, Welch JT. | Antimicrob Agents Chemother | 10.1128/aac.42.2.462 | 1998 | |
| Mycobacterium bovis in Swine: Spoligotyping of Isolates from Argentina. | Barandiaran S, Martinez Vivot M, Moras EV, Cataldi AA, Zumarraga MJ. | Vet Med Int | 10.4061/2011/979647 | 2011 | ||
| Phylogeny | Evaluation of genotype MTBC assay for differentiation of clinical Mycobacterium tuberculosis complex isolates. | Richter E, Weizenegger M, Rusch-Gerdes S, Niemann S. | J Clin Microbiol | 10.1128/jcm.41.6.2672-2675.2003 | 2003 | |
| Phylogeny | Mycobacterium africanum subtype II is associated with two distinct genotypes and is a major cause of human tuberculosis in Kampala, Uganda. | Niemann S, Rusch-Gerdes S, Joloba ML, Whalen CC, Guwatudde D, Ellner JJ, Eisenach K, Fumokong N, Johnson JL, Aisu T, Mugerwa RD, Okwera A, Schwander SK. | J Clin Microbiol | 10.1128/jcm.40.9.3398-3405.2002 | 2002 | |
| Genotyping Mycobacterium bovis from cattle in the Central Pampas of Argentina: temporal and regional trends. | Shimizu E, Macias A, Paolicchi F, Magnano G, Zapata L, Fernandez A, Canal A, Garbaccio S, Cataldi A, Caimi K, Zumarraga M. | Mem Inst Oswaldo Cruz | 10.1590/0074-0276140292 | 2014 | ||
| Comparison of PCR-generated fragments of the mce gene from Mycobacterium tuberculosis, M. avium, M. intracellulare, and M. scrofulaceum. | Parker SL, Tsai YL, Palmer CJ. | Clin Diagn Lab Immunol | 10.1128/cdli.2.6.770-775.1995 | 1995 | ||
| Pathogenicity | Activity of n-propyl pyrazinoate against pyrazinamide-resistant Mycobacterium tuberculosis: investigations into mechanism of action of and mechanism of resistance to pyrazinamide. | Speirs RJ, Welch JT, Cynamon MH. | Antimicrob Agents Chemother | 10.1128/aac.39.6.1269 | 1995 | |
| Activation of CD8 T cells with specificity for mycobacterial heat shock protein 60 in Mycobacterium bovis bacillus Calmette-Guérin-vaccinated mice. | Zugel U, Kaufmann SH. | Infect Immun | 10.1128/iai.65.9.3947-3950.1997 | 1997 | ||
| Role of interleukin-18 (IL-18) in mycobacterial infection in IL-18-gene-disrupted mice. | Sugawara I, Yamada H, Kaneko H, Mizuno S, Takeda K, Akira S. | Infect Immun | 10.1128/iai.67.5.2585-2589.1999 | 1999 | ||
| Lethal tuberculosis in interleukin-6-deficient mutant mice. | Ladel CH, Blum C, Dreher A, Reifenberg K, Kopf M, Kaufmann SH. | Infect Immun | 10.1128/iai.65.11.4843-4849.1997 | 1997 | ||
| Phylogeny | Mycobacterium bovis subsp. caprae caused one-third of human M. bovis-associated tuberculosis cases reported in Germany between 1999 and 2001. | Kubica T, Rusch-Gerdes S, Niemann S. | J Clin Microbiol | 10.1128/jcm.41.7.3070-3077.2003 | 2003 | |
| Influence of mouse strain and vaccine viability on T-cell responses induced by Mycobacterium bovis bacillus Calmette-Guérin. | Daugelat S, Ladel CH, Kaufmann SH. | Infect Immun | 10.1128/iai.63.5.2033-2040.1995 | 1995 | ||
| Attenuated activation of macrophage TLR9 by DNA from virulent mycobacteria. | Kiemer AK, Senaratne RH, Hoppstadter J, Diesel B, Riley LW, Tabeta K, Bauer S, Beutler B, Zuraw BL. | J Innate Immun | 10.1159/000142731 | 2009 | ||
| Enzymology | The superoxide dismutase gene, a target for detection and identification of mycobacteria by PCR. | Zolg JW, Philippi-Schulz S. | J Clin Microbiol | 10.1128/jcm.32.11.2801-2812.1994 | 1994 | |
| Subunit vaccination of mice against new world cutaneous leishmaniasis: comparison of three proteins expressed in amastigotes and six adjuvants. | Aebischer T, Wolfram M, Patzer SI, Ilg T, Wiese M, Overath P. | Infect Immun | 10.1128/iai.68.3.1328-1336.2000 | 2000 |
| #11440 | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 43990 |
| #20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 ) |
| #126262 | A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 ) |
You found an error in BacDive? Please tell us about it!
Note that changes will be reviewed and judged. If your changes are legitimate, changes will occur within the next BacDive update. Only proposed changes supported by the according reference will be reviewed. The BacDive team reserves the right to reject proposed changes.
Successfully sent
If you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive8542.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data