Mycobacterium tuberculosis H37Rv is a bacterium that was isolated from Human, Lung.
16S sequence Bacteria
SI-ID 15077
| @ref 20215 |
|
Last LPSN update
2026-02-09 11:41:13 |
| Domain Bacteria |
| Phylum Actinomycetota |
| Class Actinomycetes |
| Order Mycobacteriales |
| Family Mycobacteriaceae |
| Genus Mycobacterium |
| Species Mycobacterium tuberculosis |
| Full scientific name Mycobacterium tuberculosis (Zopf 1883) Lehmann and Neumann 1896 (Approved Lists 1980) |
| Synonyms (8) |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 20215 | Mycobacterium tuberculosis H37Rv 16S ribosomal RNA gene, partial sequence | MH794239 | 1537 |  | 83332 |  |
| 124043 | Mycobacterium tuberculosis 16S ribosomal RNA (rrs) gene, partial sequence. | AF059845 | 175 | | 1773 | |
| 124043 | Mycobacterium tuberculosis strain ATCC 27294 16S ribosomal RNA gene, partial sequence. | FJ468334 | 1439 | | 37915 | |
| 124043 | Mycobacterium tuberculosis strain ATCC 27294 16S ribosomal RNA gene, partial sequence. | FJ468336 | 1439 | | 37915 | |
| 124043 | Mycobacterium tuberculosis strain ATCC 27294 16S ribosomal RNA gene, partial sequence. | FJ468337 | 1440 | | 587879 | |
| 124043 | Mycobacterium tuberculosis strain ATCC 27294 16S ribosomal RNA gene, partial sequence. | FJ468338 | 1408 | | 587880 | |
| 124043 | Mycobacterium tuberculosis strain ATCC 27294 16S ribosomal RNA gene, partial sequence. | FJ468340 | 1437 | | 282305 | |
| 124043 | Mycobacterium tuberculosis strain ATCC 27294 16S ribosomal RNA gene, partial sequence. | FJ468345 | 1454 | | 1773 | |
| 124043 | Mycobacterium avium subsp. paratuberculosis strain IMR (M15/79) 16S ribosomal RNA gene, partial sequence. | JQ348116 | 214 | | 1765 | |
| 124043 | M.tuberculosis ribosomal RNA operon encoding 16S and 23S ribosomal RNA | X58890 | 2538 | | 1773 | |
| 124043 | Mycobacterium tuberculosis H37Rv strain ATCC 27294 16S ribosomal RNA gene, partial sequence. | JQ348114 | 215 | | 83332 | |
| 124043 | Mycobacterium tuberculosis subsp. tuberculosis strain CIP 64.31 16S ribosomal RNA gene, partial sequence. | AF547977 | 556 | | 182785 | |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| In vitro exposure to clofazimine can select for delamanid and pretomanid resistance in Mycobacterium tuberculosis. | Rupasinghe P, Ismail N, Mulders W, Warren RM, Joseph L, Ngcamu D, Gwala T, Omar SV, Vereecken J, de Jong BC, Rigouts L, Borroni E, Cirillo DM, Schon T, Miotto P, Koser CU. | Antimicrob Agents Chemother | 10.1128/aac.01113-25 | 2025 | | |
| In vitro assessment of Brazilian red propolis against mycobacteria: antibacterial potency, synergy, inhibition of biofilm formation, and intramacrophage effects. | Martins SB, Teixeira SC, de Souza G, Alhatlani BY, Abdallah EM, Ambrosio SR, Silva TS, Bastos JK, Tanimoto MH, Barbosa BF, Ferro EAV, Martins CHG. | Front Pharmacol | 10.3389/fphar.2025.1630134 | 2025 | | |
| Antimicrobial Activity of Solanum torvum Crude Extracts against Important Mycobacterial Strains. | Nguta JM. | Int J Mycobacteriol | 10.4103/ijmy.ijmy_69_25 | 2025 | | |
| Antimycobacterial Activity of Allium Cepa and Allium sativum Hydroethanolic Crude Extracts against Pathogenic and Nonpathogenic Mycobacterial Strains. | Nguta JM. | Int J Mycobacteriol | 10.4103/ijmy.ijmy_81_25 | 2025 | | |
| Whole genome sequence of a Mycobacterium tuberculosis M64 isolate harboring extensive deletions, including the katG-containing region. | Jeon S-M, Park S, Kim S. | Microbiol Resour Announc | 10.1128/mra.00745-24 | 2025 | | |
| Lefamulin harbors promising anti-tuberculosis activity against multidrug-resistant Mycobacterium tuberculosis isolates. | Wu J, Ji Y, Zhang W, Chen S, Dong Y, Yu X. | Microbiol Spectr | 10.1128/spectrum.02250-25 | 2025 | | |
| Enzymology | Comparative growth kinetics and drug susceptibility of Mycobacterium tuberculosis lineages prevalent in Ethiopia: implications for tuberculosis treatment and management. | Hailemariam TG, Tilahun M, Atnafu A, Gelanew T, Gebresilase TT, Tola MA, Ayele A, Siraj SM, Shibeshi W, Bobosha K, Wassie L, Hirutu Y, Engidawork E. | Front Microbiol | 10.3389/fmicb.2024.1512580 | 2024 | |
| Low-level BTZ-043 resistance in Mycobacterium tuberculosis and cross-resistance to bedaquiline and clofazimine. | Ghodousi A, Iannucci I, Saluzzo F, Dreisbach J, Mirold-Mei S, Hoelscher M, Cirillo DM. | IJTLD Open | 10.5588/ijtldopen.25.0301 | 2025 | | |
| Early preclinical development of Mycobacteriumtuberculosis amino acid biosynthesis pathway inhibitor DRILS-1398 as a potential anti-TB drug | Biswas D, Edwin R, Kumar K, Alam A, Kumar D, Chakraborty S, Bulusu G, Ahmad F, Shenoy G, Singh L, Agarwal M, Siraj F, Oruganti S, Misra P, Ehtesham N, Pal M, Hasnain S. | iScience | 2025 | | ||
| Reply to Schön et al., "Quality control and considering systematic MIC shifts are key when evaluating the role of mmpR5 (Rv0678) frameshifts in bedaquiline resistance". | Snobre J, Meehan CJ, Mulders W, Rigouts L, Buyl R, de Jong BC, Van Rie A, Tzfadia O. | Antimicrob Agents Chemother | 10.1128/aac.00317-25 | 2025 | | |
| Experimental system enables studies of Mycobacterium tuberculosis during aerogenic transmission. | Nuritdinov F, Woo J, Schmidt MJ, Odjourian NM, Cristaldo M, Dougher M, Antilus-Sainte R, Heldt T, Rhee K, Bourouiba L, Gengenbacher M. | mBio | 10.1128/mbio.00958-25 | 2025 | | |
| Tanshinones target drug-resistant tuberculosis: efficacy, selectivity, and potential mechanism of action. | Polinario G, Rosa MABC, Campos DL, Moraes LLS, de Campos MMA, Silva IGM, Barros-Cordeiro KB, Bao SN, Pavan FR. | RSC Med Chem | 10.1039/d5md00637f | 2025 | | |
| Gold Nanoparticle-Enhanced Recombinase Polymerase Amplification for Rapid Visual Detection of Mycobacterium tuberculosis. | Saikaew S, Sangboonruang S, Pongsararuk R, Srilohasin P, Butr-Indr B, Intorasoot S, Phunpae P, Tharinjaroen CS, Arunothong S, Panyasit W, Chaiprasert A, Tragoolpua K, Wattananandkul U. | Biosensors (Basel) | 10.3390/bios15090607 | 2025 | | |
| Transcriptome | Exploring the transcription start sites and other genomic features facilitates the accurate identification and annotation of small RNAs across multiple stress conditions in Mycobacterium tuberculosis. | Cheah HL, Citartan M, Lee LP, Ahmed SA, Salleh MZ, Teh LK, Tang TH. | Funct Integr Genomics | 10.1007/s10142-024-01437-5 | 2024 | |
| Genotypic diversity of Mycobacterium tuberculosis strains collected from immigrant patients in Mashhad, Iran using MIRU-VNTR method | Jangi M, Ghazvini K, Soleimanpour S, Ghavidel M, Hashemitabar G. | Iran J Microbiol | 2025 | | ||
| Genetics | Discrepancies in isoniazid susceptibility profiles: Bactec MGIT 960-resistant but GenoType MTBDRplus-susceptible Mycobacterium tuberculosis strains in Hunan, China. | Chen Z, Hu P, Guo J, Wang J, Liu B, Tan Y. | Microbiol Spectr | 10.1128/spectrum.01101-25 | 2025 | |
| Triple-synergy bactericidal action: a mannose-decorated bioinspired coating on silver-mesoporous silica for eradicating multidrug-resistant Mycobacterium tuberculosis. | Song Y, Yu D, Sheng Z, Song H, Xu J, Zhang J, Chen H, Xu P. | RSC Adv | 10.1039/d5ra07047c | 2025 | | |
| Determining the minimum inhibitory concentrations of pyrazinamide against Mycobacterium tuberculosis clinical isolates at a neutral pH of 6.8 using the broth microdilution method. | Tamblin M, Shi W, Chen L, Reynolds J. | Front Microbiol | 10.3389/fmicb.2025.1688772 | 2025 | | |
| Anti-tuberculosis activity of morusin: a promising flavonoid from white mulberry. | Yildirim K, Bozkurt S, Basibuyuk HH, Coban AY. | Int J Tuberc Lung Dis | 10.5588/ijtld.23.0224 | 2024 | | |
| A comprehensive evaluation of a novel targeted-sequencing workflow for Mycobacterium species identification and anti-tuberculosis drug-resistance detection. | Ou X, Pei S, Li H, Qin Z, Anthony R, Wang J, Song Z, Xing R, Zhang L, Teng C, Xia H, Zhou Y, Song Y, Zheng Y, Wang S, Zhao B, Zhao Y. | Front Cell Infect Microbiol | 10.3389/fcimb.2025.1584237 | 2025 | | |
| Investigation of delamanid, bedaquiline, and linezolid resistance rates and related gene mutations in multidrug-resistant Mycobacterium tuberculosis in regional tuberculosis reference laboratories of Iran. | Ahmad Khosravi N, Khosravi AD, Hashemzadeh M, Savari M, Saki M. | BMC Microbiol | 10.1186/s12866-025-04213-y | 2025 | | |
| Phylogeny | TBpore cluster: A novel phylogenetic pipeline for tuberculosis transmission studies using nanopore next-generation sequencing data. | Gagnon S, Ametepe E, Point F, Cloutier Charette W, Chakravarti A, Rivest P, Akochy PM, Soualhine H, Iqbal Z, Hall MB, Lapierre SG. | PLoS One | 10.1371/journal.pone.0325914 | 2025 | |
| Sustainable innovative nanofibers containing Cobalt-MOF: a dual-action solution for microbial and chemical wastewater contamination. | M Alqahtani S, Sur D, Altharawi A, Roopashree R, Hussein Zwamel A, Aldakhil T. | Front Chem | 10.3389/fchem.2025.1584064 | 2025 | | |
| Genetics | Sentinel-Site-Based Surveillance of Mycobacterium tuberculosis Drug Resistance and Epidemiology in Sichuan, China. | Wang Y, Liu C, Zhao B, Ou X, Xia H, Song Y, Zheng Y, Zhou Y, Xing R, Zhao Y, Zheng H. | Antibiotics (Basel) | 10.3390/antibiotics14070625 | 2025 | |
| Design, synthesis and characterization of ethyl 3-benzoyl-7-morpholinoindolizine-1-carboxylate as anti-tubercular agents: In silico screening for possible target identification. | Tiwari P, Mangubhai GS, Kidwai S, Singh R, Chandrashekharappa S. | Chem Biol Drug Des | 10.1111/cbdd.14512 | 2024 | | |
| Off-label evaluation of the BD MAX MDR-TB assay for rapid diagnosis of rifampicin and isoniazid resistance of Mycobacterium tuberculosis clinical isolates in a high-volume reference laboratory. | Brandao AP, Ferreira FMdA, Simeao FCdS, Ferrazoli L, Chimara E, de Oliveira RS, Pinhata JMW. | J Clin Microbiol | 10.1128/jcm.00912-25 | 2025 | | |
| Discovery of 1,2,3-triazole incorporated indole-piperazines as potent antitubercular agents: Design, synthesis, in vitro biological evaluation, molecular docking and ADME studies. | Reddyrajula R, Etikyala U, Manga V, Kumar Dalimba U. | Bioorg Med Chem | 10.1016/j.bmc.2023.117562 | 2024 | | |
| Synthesis and Anti-bacterial Activity of New Substituted 2-trifluoromethyl-4-quinolinylhydrazone Analogs against Mycobacterium tuberculosis Strains. | da Silva ET, de Andrade GF, Lourenco MCS, De Souza MVN. | Curr Med Chem | 10.2174/0109298673267136231003113803 | 2024 | | |
| TAK1 phosphorylation mediates macozinone (PBTZ169) induced innate immune activation against tuberculosis. | Li X, Luo X, Wang B, Fu L, Chen X, Lu Y. | mSphere | 10.1128/msphere.00513-25 | 2025 | | |
| In Vitro Antimicrobial Activity of Contezolid Against Mycobacterium tuberculosis and Absence of Cross-Resistance with Linezolid. | Wang L, Chen J, He Y, Zheng R, Wang J, Huang X, Sha W, Qin L. | Microorganisms | 10.3390/microorganisms13092216 | 2025 | | |
| Evaluation of the Xpert MTB/XDR test for detection of isoniazid, fluoroquinolones, and second-line injectable drugs resistance to Mycobacterium tuberculosis-Anhui Province, China. | Zhang R, Bao X, Bao F, Teng C, Xu D, Liu Z, Li Y, Zhao B, Xia H, Xing R, Ou X, Zhao Y. | PLoS One | 10.1371/journal.pone.0331264 | 2025 | | |
| Endogenous hepcidin plays an essential role in Mycobacterium tuberculosis Rv1876 antigen-induced antimicrobial activity in macrophages. | Park HS, Choi HG, Jang IT, Pham TA, Jiang Z, Son YJ, Kim K, Kim HJ. | Emerg Microbes Infect | 10.1080/22221751.2025.2539192 | 2025 | | |
| Protocol for the selection of Mycobacterium tuberculosis spontaneous resistant mutants to d-cycloserine. | Osorio-Gonzalez A, Alvarez N, Realpe T, Robledo J. | MethodsX | 10.1016/j.mex.2024.102690 | 2024 | | |
| Genetics | Surveillance and analysis of drug resistance and drug resistance levels in multidrug resistant tuberculosis on the tropical islands of China. | Wang J, Dong J, Chen Z, Xu Y, Qiu W, Chen S, Pei H, Zhong Y. | BMC Infect Dis | 10.1186/s12879-025-11312-8 | 2025 | |
| Microbiological evidence for the trisubstituted benzimidazoles targeting MmpL3 in Mycobacterium tuberculosis. | Zhang M, Zhang M, Allen R, Ames L, Engelhart CA, Quach D, Lv X, Xiao G, Wang H, Wang J, Zhou L, Pan M, Sugie J, Pogliano J, Schnappinger D, Parish T, Chen S. | Antimicrob Agents Chemother | 10.1128/aac.00368-25 | 2025 | | |
| Furan-thiazole hydrazone scaffolds as promising antitubercular and antibacterial agents: synthesis, characterization, bioevaluation and computational analysis. | Sable YR, Shinde RA, Yasin HKA, Ghanwate N, Mali SN, Ghotekar SK, Gawari DP, Sasane DA, Adole VA. | RSC Adv | 10.1039/d5ra04238k | 2025 | | |
| Design, Synthesis, and In Vitro Evaluation of 4-(Arylchalcogenyl)methyl)-1H-1,2,3-triazol-1-yl-menadione: Exploring Their Potential Against Tuberculosis. | Santos NLB, Gomes LS, Ribeiro RCB, Carvalho AS, Lourenco MCS, Marins LM, Valle SP, Doring TH, Andricopulo AD, Oliveira AS, Ferreira VF, da Silva FC, Forezi LDSM, Nascimento V. | Pharmaceuticals (Basel) | 10.3390/ph18060797 | 2025 | | |
| Fever-Induced Heat Shock Protein-70 Regulates Macrophage IL-1beta and IL-10 Secretion During Mycobacterium tuberculosis Infection. | Chong DLW, Shah SA, Kutschenreuter J, Cusman R, Pillai MM, Kirwan DE, Gilman RH, Friedland JS. | Eur J Immunol | 10.1002/eji.202551963 | 2025 | | |
| Identification of Mycobacterium tuberculosis intracellular survival-related virulence factors via CRISPR-based eukaryotic-like secretory protein mutant library screen. | Liu W, Wang Y, Zhao J, Zhang X, Li Z, Jia H, Zhu C, Zhang L, Pan L, Zhang Z. | Microbiol Spectr | 10.1128/spectrum.00767-25 | 2025 | | |
| Genetics | Comprehensive Whole Genome Sequencing Dataset of Mycobacterium tuberculosis Strains Collected Across Italy. | Ghodousi A, Cannas A, Tagliani E, Batignani V, Bisognin F, Borroni E, Butera O, Codecasa LR, Monte PD, De Maio F, Delogu G, Mattei G, Matteo G, Messina F, Omrani M, Perilli C, Sali M, Sotgiu G, Tadolini M, Torri S, Vismara C, Girardi E, Cirillo DM. | Sci Data | 10.1038/s41597-025-04966-1 | 2025 | |
| Polycytotoxic T cells mediate antimicrobial activity against intracellular Mycobacterium tuberculosis. | Zumwinkel M, Chirambo A, Zahnle M, Burger M, Grieshober M, Romahn V, Mwandumba H, Stenger S. | Infect Immun | 10.1128/iai.00297-24 | 2025 | | |
| Different Contributions of embB and ubiA Mutations to Variable Level of Ethambutol Resistance in Mycobacterium tuberculosis Isolates. | Nan XT, Li MC, Xiao TY, Liu HC, Lin SQ, Wang W, Qian C, Hang H, Li GL, Zhao XQ, Wan KL, Zhao LL. | Infect Drug Resist | 10.2147/idr.s466371 | 2024 | | |
| A vaccine targeting lung resident-memory CD4+ T cell phenotype protects against Mycobacterium tuberculosis in mice. | Ko KH, Baek SH, Bae HS, Kim YM, Gu SH, Jung YY, Kwak EH, Choi HG, Kim HJ, Shim TS, Kim DH, Bin Cha S. | NPJ Vaccines | 10.1038/s41541-025-01225-7 | 2025 | | |
| The Effect of Inoculum Size on Antimicrobial Susceptibility Testing of Mycobacterium tuberculosis. | Yildirim K, Atas C, Simsek E, Coban AY. | Microbiol Spectr | 10.1128/spectrum.00319-23 | 2023 | | |
| Therapeutic potential of Bacillus sonorensis PMC204 membrane vesicles against drug-resistant Mycobacterium tuberculosis. | Lee Y, Seo H, Lee S, Choi D, Kim S, Rahim MA, Song HY. | Med Microbiol Immunol | 10.1007/s00430-025-00851-1 | 2025 | | |
| Investigating the Mechanism of Antimycobacterial and Antiproliferative Activity of (E)-N'-Benzylidenepyrazine-2-Carbohydrazides and their Derivatives. | Houngbedji PA, Nawrot DE, Jandourek O, Konecna K, Novak M, Paterova P, Barta P, Rambaher MH, Novotna E, Castellano C, Mori M, Meneghetti F, Zahorszka M, Kordulakova J, Zitko J. | ChemMedChem | 10.1002/cmdc.202500085 | 2025 | | |
| Nifuroxazide and 4-Hydroxybenzhydrazone Derivatives as New Antiparasitic (Trypanosoma cruzi and Leishmania mexicana) and Anti-Mycobacterium tuberculosis Agents. | Delgado-Maldonado T, Navarrete-Carriola DV, Vazquez-Jimenez LK, Paz-Gonzalez AD, Wan B, Franzblau S, Mohammed OM, Rodriguez-Paez L, Aguirre-Alvarado C, Alcantara-Farfan V, Cordero-Martinez J, Bandyopadhyay D, Moreno-Rodriguez A, Rivera G. | Pharmaceutics | 10.3390/pharmaceutics17050621 | 2025 | | |
| Comprehensive evaluation of the MeltPro MTB/PZA assay for prediction of pyrazinamide resistance in multidrug-resistant tuberculosis. | He G, Tu C, Zhu Y, Zheng Q, Zhou Q, Zhou W, Huang O, Chen B, Liu Z, Xu Y, Jiang X. | Microbiol Spectr | 10.1128/spectrum.02745-24 | 2025 | | |
| Rapid and simple detection of HCV RNA: enhanced colorimetric RT-LAMP method using unmodified gold nanoparticles. | Altin H, Agel E, Tosun AI. | BMC Microbiol | 10.1186/s12866-025-04465-8 | 2025 | | |
| Development and preliminary assessment of the iFIND TBR: all-in- one molecular diagnostic assay for rapid detection of Mycobacterium tuberculosis and rifampicin resistance. | Ou X, Song Z, Xing R, Zhao B, Pei S, Teng C, Zhang L, Sun Q, Liu F, Xia H, Zhou Y, Zheng Y, Song Y, Zhang Z, Wang S, Anthony R, Zhao Y. | Front Cell Infect Microbiol | 10.3389/fcimb.2024.1439099 | 2024 | | |
| Validation study of a novel, rapid, open platform real-time LAMP assay for early diagnosis of pulmonary tuberculosis. | Nair SS, Varghese RE, Saji A, Thekkuveettil A. | Sci Rep | 10.1038/s41598-025-93565-6 | 2025 | | |
| Novel Antibacterial Activity of Febuxostat, an FDA-Approved Antigout Drug against Mycobacterium tuberculosis Infection. | Kim LH, Kang SM, Whang J, Kwon KW, Shin SJ. | Antimicrob Agents Chemother | 10.1128/aac.00762-22 | 2022 | | |
| Performance of a broth microdilution assay for routine minimum inhibitory concentration determination of 14 anti-tuberculous drugs against the Mycobacterium tuberculosis complex based on the EUCAST reference protocol. | Mansjo M, Espinosa-Gongora C, Samanci I, Groenheit R, Werngren J. | Antimicrob Agents Chemother | 10.1128/aac.00946-24 | 2025 | | |
| Sudapyridine (WX-081) inhibits Mycobacterium tuberculosis by targeting ATP synthase and upregulating host innate immunity. | Li X, Luo X, Wang B, Fu L, Chen X, Lu Y. | mSphere | 10.1128/msphere.00149-25 | 2025 | | |
| Kinetics of Granuloma, IFN-gamma and IP-10 in a Wistar Rat Model Infected with Mycobacterium Tuberculosis. | Singh B, Wasita B, Reviono R. | Med Arch | 10.5455/medarh.2022.76.248-251 | 2022 | | |
| Genetics | Genotypic and phenotypic drug resistance patterns of Mycobacterium tuberculosis isolated from presumptive pulmonary tuberculosis patients in Ethiopia: A multicenter study. | Yenew B, Kebede A, Alemu A, Diriba G, Mehammed Z, Amare M, Dagne B, Sinshaw W, Tesfaye E, Beyene D, Abegaz WE. | PLoS One | 10.1371/journal.pone.0303460 | 2024 | |
| Bioassay-guided isolation and structure elucidation of anti-mycobacterium tuberculosis compounds from Galatella grimmii (Regel & Schmalh.) Sennikov. | Shakeri A, Tajvar M, Tabrizi GT, Soleimanpour S, Davoodi J, Asili J, Amiri MS, Emami SA. | BMC Complement Med Ther | 10.1186/s12906-024-04632-w | 2024 | | |
| Sphingosine kills Mycobacteria and suppresses mycobacterial lung infections. | Wu Y, Schnitker F, Liu Y, Keitsch S, Caicci F, Schumacher F, Riehle A, Pollmeier B, Kehrmann J, Kleuser B, Kamler M, Szabo I, Grassme H, Gulbins E. | J Mol Med (Berl) | 10.1007/s00109-025-02534-z | 2025 | | |
| Mycobacterium tuberculosis Infection of Retinal Endothelial Cells Induces Interferon Signaling Activation: Insights Into Tubercular Retinal Vasculitis. | Putera I, Swagemakers SMA, Nagtzaam NMA, van Holten-Neelen C, La Distia Nora R, de Steenwinkel JEM, Rombach SM, van Hagen PM, Dik WA. | Invest Ophthalmol Vis Sci | 10.1167/iovs.66.9.48 | 2025 | | |
| Synthesis and pharmacological evaluation of 1,3-diaryl substituted pyrazole based (thio)urea derivatives as potent antimicrobial agents against multi-drug resistant Staphylococcus aureus and Mycobacterium tuberculosis. | Ommi O, Naiyaz Ahmad M, Gajula SNR, Wanjari P, Sau S, Agnivesh PK, Sahoo SK, Kalia NP, Sonti R, Nanduri S, Dasgupta A, Chopra S, Yaddanapudi VM. | RSC Med Chem | 10.1039/d3md00079f | 2023 | | |
| Synthesis and biological evaluation of new naphthalimide-thiourea derivatives as potent antimicrobial agents active against multidrug-resistant Staphylococcus aureus and Mycobacterium tuberculosis. | Rana P, Parupalli R, Akhir A, Saxena D, Maitra R, Imran M, Malik P, Mahammad Ghouse S, Joshi SV, Srikanth D, Madhavi YV, Dasgupta A, Chopra S, Nanduri S. | RSC Med Chem | 10.1039/d4md00062e | 2024 | | |
| Utility of Rapid Molecular Assays for Detecting Multidrug-Resistant Mycobacterium tuberculosis in Extrapulmonary Samples. | Kania K, Wojcik K, Drozdz K, Klesiewicz K. | Diagnostics (Basel) | 10.3390/diagnostics15091113 | 2025 | | |
| Evaluation of in vitro susceptibility to sparteine in four strains of Mycobacterium tuberculosis. | Hidalgo M, Asmat Marrufo P, Lezama Asencio P, Ramos C, Chimoy Tunoque CA, Zolla G. | Rev Peru Med Exp Salud Publica | 10.17843/rpmesp.2022.391.10136 | 2022 | | |
| Predicting fitness in Mycobacterium tuberculosis with transcriptional regulatory network-informed interpretable machine learning. | Bustad E, Petry E, Gu O, Griebel BT, Rustad TR, Sherman DR, Yang JH, Ma S. | Front Tuberc | 10.3389/ftubr.2025.1500899 | 2025 | | |
| A simplified pyrazinamidase test for Mycobacterium tuberculosis pyrazinamide antimicrobial susceptibility testing. | Chan H-H, Wang Y-C, Jou R. | J Clin Microbiol | 10.1128/jcm.01227-24 | 2024 | | |
| In Vitro and In Vivo Activity of Gepotidacin against Drug-Resistant Mycobacterial Infections. | Ahmad MN, Garg T, Singh S, Shukla R, Malik P, Krishnamurthy RV, Kaur P, Chopra S, Dasgupta A. | Antimicrob Agents Chemother | 10.1128/aac.00564-22 | 2022 | | |
| Host Translational Control by Stress Granules Promotes Mycobacterium tuberculosis Pathogenesis. | Kim J, Son SH, Choi JA, Lee J, Jo S, Cho SN, Nguyen DT, Son D, Kim KK, Song CH. | MedComm (2020) | 10.1002/mco2.70479 | 2025 | | |
| A new N-acylhydrazone oxadiazole derivative with activity against mycobacteria. | Souza IV, Froes da Motta Dacome ML, Frederico Rozada AM, Rosa JS, Sampiron EG, Ferreira DG, Gauze GF, Norman Negri MF, de Lima Scodro RB, Cardoso RF, Caleffi-Ferracioli KR. | Future Microbiol | 10.1080/17460913.2024.2412439 | 2025 | | |
| The Repurposing of FDA-Approved Drugs as FtsZ Inhibitors against Mycobacterium tuberculosis: An In Silico and In Vitro Study. | Tovar-Nieto AM, Flores-Padilla LE, Rivas-Santiago B, Trujillo-Paez JV, Lara-Ramirez EE, Jacobo-Delgado YM, Lopez-Ramos JE, Rodriguez-Carlos A. | Microorganisms | 10.3390/microorganisms12081505 | 2024 | | |
| Hydrazineyl-linked imidazole[1,2-a]pyrimidine-thiazole hybrids: design, synthesis, and in vitro biological evaluation studies. | P D, Naik S, D U, B C R, Ranjan V, Veeranagaiah NS. | RSC Adv | 10.1039/d5ra04692k | 2025 | | |
| The Parkinson's drug benztropine possesses histamine receptor 1-dependent host-directed antimicrobial activity against Mycobacterium tuberculosis. | Sahile HA, Christofferson M, Alford MA, Rens C, Haghdadi H, Chao JD, Langdon G, Hancock REW, Chen J, Av-Gay Y. | NPJ Antimicrob Resist | 10.1038/s44259-025-00143-x | 2025 | | |
| Pathogenicity | Mycobacterium tuberculosis protein Rv2652c enhances intracellular survival by inhibiting host immune responses. | Li J, Dou Y. | Immun Inflamm Dis | 10.1002/iid3.70012 | 2024 | |
| Efflux pumps positively contribute to rifampin resistance in rpoB mutant Mycobacterium tuberculosis | Meng F, Chen Y, Wei Z, Liu Z, Lai X, Lei J, Wu L, Deng L, Wang Q, Yang Y, Li H, Xie B, Gong L, Niu Q, Gao J, Wang N, Hu J. | Ann Clin Microbiol Antimicrob | 2025 | | ||
| Nosiheptide Harbors Potent In Vitro and Intracellular Inhbitory Activities against Mycobacterium tuberculosis. | Yu X, Zhu R, Geng Z, Kong Y, Wang F, Dong L, Zhao L, Xue Y, Ma X, Huang H. | Microbiol Spectr | 10.1128/spectrum.01444-22 | 2022 | | |
| Development of CRISPR/Cas12b-Based Multiple Cross Displacement Amplification Technique for the Detection of Mycobacterium tuberculosis Complex in Clinical Settings. | Yang X, Huang J, Chen Y, Ying X, Tan Q, Chen X, Zeng X, Lei S, Wang Y, Li S. | Microbiol Spectr | 10.1128/spectrum.03475-22 | 2023 | | |
| Rapid detection of drug-resistant Mycobacterium tuberculosis by Modified MODS assay suitable for resource-poor settings. | Fomda BA, Bashir G, Baqal S, Mir YB, Ali R, Khan AH, Khan A, Bashir A, Chuloo GM. | PLoS Negl Trop Dis | 10.1371/journal.pntd.0011852 | 2024 | | |
| Discordant results between Xpert MTB/RIF assay and Bactec MGIT 960 culture system regarding the detection of rifampin-resistant Mycobacterium tuberculosis isolates in Wenzhou, China. | He G, Zheng Q, Wu J, Wu L, Geng Z, Jiang G, Huang H, Jiang X, Yu X. | Microbiol Spectr | 10.1128/spectrum.03859-23 | 2024 | | |
| Rapid and Visual Differentiation of Mycobacterium tuberculosis From the Mycobacterium tuberculosis Complex Using Multiplex Loop-Mediated Isothermal Amplification Coupled With a Nanoparticle-Based Lateral Flow Biosensor. | Yang X, Huang J, Chen X, Xiao Z, Wang X, Chen Y, Zheng W, Chen W, Chen H, Lei S, Hu Y, Li S. | Front Microbiol | 10.3389/fmicb.2021.708658 | 2021 | | |
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| Optimization, characterization, and cytotoxicity studies of novel anti-tubercular agent-loaded liposomal vesicles. | Obiedallah MM, Mironov MA, Belyaev DV, Ene A, Vakhrusheva DV, Krasnoborova SY, Bershitsky SY, Shchepkin DV, Minin AS, Ishmetova RI, Ignatenko NK, Tolshchina SG, Fedorova OV, Rusinov GL. | Sci Rep | 10.1038/s41598-023-49576-2 | 2024 | | |
| Triazolopyrimidines Target Aerobic Respiration in Mycobacterium tuberculosis. | Shelton C, McNeil M, Allen R, Flint L, Russell D, Berube B, Korkegian A, Ovechkina Y, Parish T. | Antimicrob Agents Chemother | 10.1128/aac.02041-21 | 2022 | | |
| Contezolid can replace linezolid in a novel combination with bedaquiline and pretomanid in a murine model of tuberculosis. | Almeida D, Li S-Y, Lee J, Hafkin B, Mdluli K, Fotouhi N, Nuermberger EL. | Antimicrob Agents Chemother | 10.1128/aac.00789-23 | 2023 | | |
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| Synthesis, Characterisation, Biological Evaluation and In Silico Studies of Quinoline-1,2,3-Triazole-Anilines as Potential Antitubercular and Anti-HIV Agents. | Magwaza SS, Naidu D, Oyeneyin OE, Senzani S, Mkhwanazi NP, Tukulula M. | Molecules | 10.3390/molecules30102119 | 2025 | | |
| HadBD dehydratase from Mycobacterium tuberculosis fatty acid synthase type II: A singular structure for a unique function. | Bories P, Rima J, Tranier S, Marcoux J, Grimoire Y, Tomaszczyk M, Launay A, Fata K, Marrakchi H, Burlet-Schiltz O, Mourey L, Ducoux-Petit M, Bardou F, Bon C, Quemard A. | Protein Sci | 10.1002/pro.4964 | 2024 | | |
| Immune Response to the Recombinant Apa Protein from Mycobacterium tuberculosis Expressed in Streptomyces lividans After Intranasal Administration in Mice. Induction of Protective Response to Tubercle Bacillus Aerosols Exposure. | Martinez-Sotelo JA, Vallecillo AJ, Parada C, Segura E, Campuzano J, Silva-Miranda M, Servin-Gonzalez L, Espitia C. | Curr Microbiol | 10.1007/s00284-024-03697-7 | 2024 | | |
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| Analysis of relative genes expression and mutation of pstB and efpA efflux pumps in Mycobacterium simiae isolates from suspected tuberculosis patients by using quantitative Real-time PCR. | Hashemzadeh M, Hasanvand M, Montazeri EA. | BMC Microbiol | 10.1186/s12866-025-03843-6 | 2025 | | |
| Two Cases of Mycobacterium shinjukuense Pulmonary Disease With a Long-Term Response to Treatment With Clarithromycin, Rifampicin, and Ethambutol. | Imakura T, Kakiuchi S, Kagawa H, Murakami N, Haku T. | Cureus | 10.7759/cureus.52888 | 2024 | | |
| Histone deacetylase (HDAC) inhibitors- based drugs are effective to control Mycobacterium tuberculosis infection and promote the sensibility for rifampicin in MDR strain. | Rodriguez-Carlos A, Jacobo-Delgado Y, Santos-Mena AO, Garcia-Hernandez MH, De Jesus-Gonzalez LA, Lara-Ramirez EE, Rivas-Santiago B. | Mem Inst Oswaldo Cruz | 10.1590/0074-02760230143 | 2023 | | |
| A smooth tubercle bacillus from Ethiopia phylogenetically close to the Mycobacterium tuberculosis complex. | Yenew B, Ghodousi A, Diriba G, Tesfaye E, Cabibbe AM, Amare M, Moga S, Alemu A, Dagne B, Sinshaw W, Mollalign H, Meaza A, Tadesse M, Gamtesa DF, Abebaw Y, Seid G, Zerihun B, Getu M, Chiacchiaretta M, Gaudin C, Marceau M, Didelot X, Tolera G, Abdella S, Kebede A, Getahun M, Mehammed Z, Supply P, Cirillo DM. | Nat Commun | 10.1038/s41467-023-42755-9 | 2023 | | |
| The implications of mutations in multiple genes associated with ethambutol resistance among multidrug-resistant tuberculosis isolates from China. | Li MC, Wang W, Xiao TY, Liu HC, Lin SQ, Hang H, Bo XL, Nan XT, Qian C, Fan XT, Zhao XQ, Li GL, Wan KL, Zhao LL. | BMC Microbiol | 10.1186/s12866-025-03821-y | 2025 | | |
| Detection of Mycobacterium tuberculosis Rifampicin Resistance Conferred by Borderline rpoB Mutations: Xpert MTB/RIF is Superior to Phenotypic Drug Susceptibility Testing. | Xia H, Song Y, Zheng Y, Wang S, Zhao B, He W, Liu D, Ou X, Zhou Y, Zhao Y. | Infect Drug Resist | 10.2147/idr.s358301 | 2022 | | |
| Repurposing an Antioxidant to Kill Mycobacterium tuberculosis by Targeting the 50S Subunit of the Ribosome. | Dong W, Wang G, Bai Y, Li Y, Zhao L, Lu W, Wang C, Zhang Z, Lu H, Wang X, Chen H, Tan C. | Biomolecules | 10.3390/biom13121793 | 2023 | | |
| Genetics | Bedaquiline Resistance and Molecular Characterization of Rifampicin-Resistant Mycobacterium Tuberculosis Isolates in Zhejiang, China. | Tong E, Zhou Y, Liu Z, Zhu Y, Zhang M, Wu K, Pan J, Jiang J. | Infect Drug Resist | 10.2147/idr.s429003 | 2023 | |
| Drug resistance and the genotypic characteristics of rpoB and katG in rifampicin- and/or isoniazid-resistant Mycobacterium tuberculosis isolates in central Vietnam. | Nguyen TBN, Nguyen TKD, Truong VH, Tran TTN, Phan VBT, Nguyen TT, Nguyen HB, Ngo VQT, Mai VT, Molicotti P. | Osong Public Health Res Perspect | 10.24171/j.phrp.2023.0124 | 2023 | | |
| The importance of heteroresistance and efflux pumps in bedaquiline-resistant Mycobacterium tuberculosis isolates from Iran. | Madadi-Goli N, Ahmadi K, Kamakoli MK, Azizi M, Khanipour S, Dizaji SP, Nasehi M, Siadat SD, Fateh A, Vaziri F. | Ann Clin Microbiol Antimicrob | 10.1186/s12941-024-00694-3 | 2024 | | |
| 5-Fluoroindole Reduces the Bacterial Burden in a Murine Model of Mycobacterium tuberculosis Infection. | Neves CE, Paz JD, Abbadi BL, Rambo RS, Czeczot AM, Sperotto NDM, Dadda AS, Silva RBM, Perello MA, Goncalves GA, Gonzalez LC, Bizarro CV, Machado P, Basso LA. | ACS Omega | 10.1021/acsomega.4c03981 | 2024 | | |
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| Multiple mechanisms enable broad-spectrum activity of the Pelargonium sidoides root extract EPs 7630 against acute respiratory tract infections. | Cinatl J, Wass MN, Michaelis M. | Front Pharmacol | 10.3389/fphar.2024.1455870 | 2024 | | |
| In vitro Activity of Repurposed Nitroxoline Against Clinically Isolated Mycobacteria Including Multidrug-Resistant Mycobacterium tuberculosis. | Hoffmann AM, Wolke M, Rybniker J, Plum G, Fuchs F. | Front Pharmacol | 10.3389/fphar.2022.906097 | 2022 | | |
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| Two target genes based multiple cross displacement amplification combined with a lateral flow biosensor for the detection of Mycobacterium tuberculosis complex. | Huang J, Xiao Z, Yang X, Chen X, Wang X, Chen Y, Zheng W, Chen W, Chen H, Li S. | BMC Microbiol | 10.1186/s12866-021-02328-6 | 2021 | | |
| Crystal structure of dihydroneopterin aldolase from Mycobacterium tuberculosis associated with 8-mercaptoguanine, and development of novel S8-functionalized analogues as inhibitors: Synthesis, enzyme inhibition, in vitro toxicity and antitubercular activity. | Czeczot AM, Muniz MN, Perello MA, Silva EED, Timmers LFSM, Berger A, Gonzalez LC, Arrache Goncalves G, Moura S, Machado P, Bizarro CV, Basso LA. | J Enzyme Inhib Med Chem | 10.1080/14756366.2024.2388207 | 2024 | | |
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| Exploring the potential of Lactocaseibacillus rhamnosus PMC203 in inducing autophagy to reduce the burden of Mycobacterium tuberculosis. | Rahim MA, Seo H, Kim S, Barman I, Ghorbanian F, Hossain MS, Shuvo MSH, Lee S, Song HY. | Med Microbiol Immunol | 10.1007/s00430-024-00794-z | 2024 | | |
| Identification of a phenyl ester covalent inhibitor of caseinolytic protease and analysis of the ClpP1P2 inhibition in mycobacteria. | Xiao G, Cui Y, Zhou L, Niu C, Wang B, Wang J, Zhou S, Pan M, Chan CK, Xia Y, Xu L, Lu Y, Chen S. | mLife | 10.1002/mlf2.12169 | 2025 | | |
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| Antimycobacterial Activity of Hedeoma drummondii against Mycobacterium tuberculosis and Non-Tuberculous Mycobacteria. | Molina-Torres C, Pedraza-Rodriguez C, Vera-Cabrera L, Ocampo-Candiani J, Rivas-Morales C, Viveros-Valdez E. | Antibiotics (Basel) | 10.3390/antibiotics12050833 | 2023 | | |
| Toxoplasma gondii macrophage migration inhibitory factor shows anti-Mycobacterium tuberculosis potential via AZIN1/STAT1 interaction. | Yoon C, Kim HK, Ham YS, Gil WJ, Mun SJ, Cho E, Yuk JM, Yang CS. | Sci Adv | 10.1126/sciadv.adq0101 | 2024 | | |
| New Rufomycins from Streptomyces atratus MJM3502 Expand Anti-Mycobacterium tuberculosis Structure-Activity Relationships. | Zhou B, Shetye G, Wolf NM, Chen SN, Qader M, Ray GJ, Lankin DC, Cho S, Cheng J, Suh JW, Franzblau SG, McAlpine JB, Pauli GF. | Org Lett | 10.1021/acs.orglett.2c02493 | 2022 | | |
| Rv1453 is associated with clofazimine resistance in Mycobacterium tuberculosis. | Zhang L, Zhang Y, Li Y, Huo F, Chen X, Zhu H, Guo S, Fu L, Wang B, Lu Y. | Microbiol Spectr | 10.1128/spectrum.00002-23 | 2023 | | |
| Serine protease Rv2569c facilitates transmission of Mycobacterium tuberculosis via disrupting the epithelial barrier by cleaving E-cadherin. | Zang X, Zhang J, Jiang Y, Feng T, Cui Y, Wang H, Cui Z, Dang G, Liu S. | PLoS Pathog | 10.1371/journal.ppat.1012214 | 2024 | | |
| Indole-fused spirochromenes as potential anti-tubercular agents: design, synthesis and in vitro evaluation. | Dogamanti A, Chiranjeevi P, Aamate VK, Vagolu SK, Sriram D, Balasubramanian S, Sarasija M. | Mol Divers | 10.1007/s11030-020-10108-z | 2021 | | |
| Potential Anti-Mycobacterium tuberculosis Activity of Plant Secondary Metabolites: Insight with Molecular Docking Interactions. | Kumar M, Singh SK, Singh PP, Singh VK, Rai AC, Srivastava AK, Shukla L, Kesawat MS, Kumar Jaiswal A, Chung SM, Kumar A. | Antioxidants (Basel) | 10.3390/antiox10121990 | 2021 | | |
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| Antibacterial activity of new substituted 4-N-alkylated-2-trifluoromethyl-quinoline analogues against sensitive and resistant Mycobacterium tuberculosis strains. | da Silva ET, de Andrade GF, Araujo ADS, Lourenco MCS, de Souza MVN. | Eur J Pharm Sci | 10.1016/j.ejps.2020.105596 | 2021 | | |
| Genetics | Whole Genomic Analysis Revealed High Genetic Diversity and Drug-Resistant Characteristics of Mycobacterium tuberculosis in Guangxi, China. | Liang D, Song Z, Liang X, Qin H, Huang L, Ye J, Lan R, Luo D, Zhao Y, Lin M. | Infect Drug Resist | 10.2147/idr.s410828 | 2023 | |
| A potent phenylalkylamine disrupts mycobacterial membrane bioenergetics and augments bactericidal activity of bedaquiline. | Phua ZY, Li M, Ali A, Cheong CCS, Goh KJ, Seto MYK, Ng ASY, Sarathy JP, Goh BC, Go ML, Chui WK, Dick T, Lam Y. | iScience | 10.1016/j.isci.2025.112915 | 2025 | | |
| Pathogenicity | Modulation of Cystatin F in Human Macrophages Impacts Cathepsin-Driven Killing of Multidrug-Resistant Mycobacterium tuberculosis. | Mandal M, Pires D, Catalao MJ, Azevedo-Pereira JM, Anes E. | Microorganisms | 10.3390/microorganisms11071861 | 2023 | |
| Enzymology | Population pharmacokinetics and dose evaluations of linezolid in the treatment of multidrug-resistant tuberculosis. | Zhang H, He Y, Davies Forsman L, Paues J, Werngren J, Niward K, Schon T, Bruchfeld J, Alffenaar JW, Hu Y. | Front Pharmacol | 10.3389/fphar.2022.1032674 | 2022 | |
| Exploring intracellular anti-mycobacterium activity of lactoferricin-loaded niosomes: proteomics insights into Immunomodulation. | Sangboonruang S, Semakul N, Poomanee W, Thavanapong T, Roytrakul S, Charoenlappanit S, Thaisakun S, Khantipongse J, Netirat N, Tongsong A, Wattananandkul U, Intorasoot S, Phunpae P, Tragoolpua K. | Sci Rep | 10.1038/s41598-025-04673-2 | 2025 | | |
| Synthesis and evaluation of triazole congeners of nitro-benzothiazinones potentially active against drug resistant Mycobacterium tuberculosis demonstrating bactericidal efficacy. | Sahoo SK, Ahmad MN, Kaul G, Nanduri S, Dasgupta A, Chopra S, Yaddanapudi VM. | RSC Med Chem | 10.1039/d1md00387a | 2022 | | |
| IFNgamma-secreting T cells that highly express IL-2 potently inhibit the growth of intracellular M. tuberculosis in macrophages. | Zhu L, Wang B, Gu J, Zhou J, Wu Y, Xu W, Yang M, Cai X, Shen H, Lu L, Wang F. | Front Immunol | 10.3389/fimmu.2024.1469118 | 2024 | | |
| Rapid, ultrasensitive, and highly specific identification of Brucella abortus utilizing multiple cross displacement amplification combined with a gold nanoparticles-based lateral flow biosensor. | Yang X, Wang Y, Liu Y, Huang J, Wei X, Tan Q, Zeng X, Ying X, Li S. | Front Microbiol | 10.3389/fmicb.2022.1071928 | 2022 | | |
| Nucleotidyltransferase toxin MenT extends aminoacyl acceptor ends of serine tRNAs to control Mycobacterium tuberculosis growth. | Xu X, Barriot R, Voisin B, Arrowsmith TJ, Usher B, Gutierrez C, Han X, Pages C, Redder P, Blower TR, Neyrolles O, Genevaux P. | Nat Commun | 10.1038/s41467-024-53931-w | 2024 | | |
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| Spontaneous mutational patterns and novel mutations for bedaquiline and clofazimine resistance in Mycobacterium tuberculosis. | Shi J, Liu Y, Wu T, Li L, Han S, Peng X, Shang Y, Guo Y, Pang Y, Gao M, Lu J. | Microbiol Spectr | 10.1128/spectrum.00090-23 | 2023 | | |
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| Flavonoids of Chromolaena odorata (L.) R.M.King & H.Rob. as potential leads for treatment against tuberculosis. | Omokhua-Uyi AG, Madikizela B, Aro AO, Abdalla MA, Van Staden J, McGaw LJ. | S Afr J Bot | 10.1016/j.sajb.2023.05.002 | 2023 | | |
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| Unveiling the Antimycobacterial Potential of Novel 4-Alkoxyquinolines: Insights into Selectivity, Mechanism of Action, and In Vivo Exposure. | da Silva FF, Paz JD, Rambo RS, Goncalves GA, Muniz MN, de Matos Czeczot A, Perello MA, Berger A, Gonzalez LC, Duarte LS, da Silva AB, Ferreira CAS, de Oliveira SD, Moura S, Bizarro CV, Basso LA, Machado P. | J Med Chem | 10.1021/acs.jmedchem.4c01302 | 2024 | | |
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| Phenotype | Splenic marginal zone B cells restrict Mycobacterium tuberculosis infection by shaping the cytokine pattern and cell-mediated immunity. | Tsai CY, Oo M, Peh JH, Yeo BCM, Aptekmann A, Lee B, Liu JJJ, Tsao WS, Dick T, Fink K, Gengenbacher M. | Cell Rep | 10.1016/j.celrep.2024.114426 | 2024 | |
| Proteome | UHPLC-HRMS/MS Chemical Fingerprinting of the Bioactive Partition from Cultivated Piper aduncum L. | de Luna AV, Fagundes TDSF, Ramos YJ, de Araujo MH, Muzitano MF, Calixto SD, Simao TLBV, de Queiroz GA, Guimaraes EF, Marques AM, Moreira DL. | Molecules | 10.3390/molecules29081690 | 2024 | |
| Investigation of the antimycobacterial activity of African medicinal plants combined with chemometric analysis to identify potential leads. | Moyo P, Ofori M, Bodede OS, Wooding M, Khorommbi NK, McGaw LJ, Danquah CA, Maharaj VJ. | Sci Rep | 10.1038/s41598-024-65369-7 | 2024 | | |
| The effect of isolated probiotics from Indonesian Passiflora edulis sims. on interferon gamma levels in peripheral blood mononuclear cell of adult tuberculosis patients in vitro. | Nurrosyidah IH, Mertaniasih NM, Isnaeni I. | J Public Health Afr | 10.4081/jphia.2023.2504 | 2023 | | |
| Mercuric-sulphide based metallopharmaceutical formulation as an alternative therapeutic to combat viral and multidrug-resistant (MDR) bacterial infections. | Malarvizhi K, Ramyadevi D, Vedha Hari BN, Sarveswari HB, Solomon AP, Fang H, Luo RH, Zheng YT. | Sci Rep | 10.1038/s41598-023-43103-z | 2023 | | |
| Prediction of pyrazinamide resistance in Mycobacterium tuberculosis using structure-based machine-learning approaches. | Carter JJ, Walker TM, Walker AS, Whitfield MG, Morlock GP, Lynch CI, Adlard D, Peto TEA, Posey JE, Crook DW, Fowler PW. | JAC Antimicrob Resist | 10.1093/jacamr/dlae037 | 2024 | | |
| Clinical Validation of the Xpert MTB/RIF Test for Identification of the Mycobacterium tuberculosis Complex in Acid-Fast Bacillus Smear-Positive MGIT Broth Cultures. | Armstrong DT, Fisher S, Totten M, Schwartz M, Gnanashanmugam D, Parrish N. | J Clin Microbiol | 10.1128/jcm.02164-21 | 2022 | | |
| Synthesis of Novel Triazine-Based Chalcones and 8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepines as Potential Leads in the Search of Anticancer, Antibacterial and Antifungal Agents. | Moreno LM, Quiroga J, Abonia R, Crespo MDP, Aranaga C, Martinez-Martinez L, Sortino M, Barreto M, Burbano ME, Insuasty B. | Int J Mol Sci | 10.3390/ijms25073623 | 2024 | | |
| Unlocking the biological potential of transition metal complexes with Thiosemicarbazone ligands: Insights from computational studies. | Khurana D, Kumar B, Devi J, Antil N, Patil RB, Singh K, Singh Y. | Heliyon | 10.1016/j.heliyon.2024.e33150 | 2024 | | |
| NMI-SO2Cl2-Mediated Amide Bond Formation: Facile Synthesis of Some Dihydrotriazolopyrimidine Amide Derivatives as Potential Anti-Inflammatory and Anti-Tubercular Agents. | Babu A, Sunil K, Sajith AM, Reddy EK, Santra S, Zyryanov GV, Venkatesh T, Bhadrachari S, Nibin Joy M. | Pharmaceuticals (Basel) | 10.3390/ph17050548 | 2024 | | |
| ZDHHC2 promoted antimycobacterial responses by selective autophagic degradation of B-RAF and C-RAF in macrophages. | Sheng J, You X, Nie D, Fu Y, Ling Q, Yang X, Chen Y, Ma L, Hu S. | Sci Adv | 10.1126/sciadv.adq7706 | 2025 | | |
| Expression and epitope prediction of MPT64 recombinant proteins from clinical isolates of Mycobacterium tuberculosis as immunoserodiagnostic candidates. | Fihiruddin F, Inayati N, Jannah R, Unsunnidhal L, Kusumawati A. | Vet World | 10.14202/vetworld.2022.2376-2383 | 2022 | | |
| A comprehensive update to the Mycobacterium tuberculosis H37Rv reference genome. | Chitale P, Lemenze AD, Fogarty EC, Shah A, Grady C, Odom-Mabey AR, Johnson WE, Yang JH, Eren AM, Brosch R, Kumar P, Alland D. | Nat Commun | 10.1038/s41467-022-34853-x | 2022 | | |
| Rifampicin resistance in Mycobacterium tuberculosis in Iran: a two-centre study. | Bahraminia F, Zangiabadian M, Nasiri MJ, Fattahi M, Goudarzi M, Ranjbar R, Imani Fooladi AA. | New Microbes New Infect | 10.1016/j.nmni.2021.100909 | 2021 | | |
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| rpoB Mutations are Associated with Variable Levels of Rifampin and Rifabutin Resistance in Mycobacterium tuberculosis. | Li MC, Wang XY, Xiao TY, Lin SQ, Liu HC, Qian C, Xu D, Li GL, Zhao XQ, Liu ZG, Zhao LL, Wan KL. | Infect Drug Resist | 10.2147/idr.s386863 | 2022 | | |
| Activity of Semi-Synthetic Mulinanes against MDR, Pre-XDR, and XDR Strains of Mycobacterium tuberculosis. | Martinez-Gonzalez MA, Pena-Rodriguez LM, Uc-Cachon AH, Borquez J, Simirgiotis MJ, Barrios-Garcia HB, Hernandez-Pando R, Loyola LA, Areche C, Dzul-Beh AJ, Barrios-Payan JA, Mata-Espinosa D, Escalante-Erosa F, Garcia-Sosa K, Molina-Salinas GM. | Metabolites | 10.3390/metabo11120876 | 2021 | | |
| Genetic Characterization Conferred Co-Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis Isolates from Southern Xinjiang, China. | Cao B, Mijiti X, Deng LL, Wang Q, Yu JJ, Anwaierjiang A, Qian C, Li M, Fang DA, Jiang Y, Zhao LL, Zhao X, Wan K, Liu H, Li G, Yuan X. | Infect Drug Resist | 10.2147/idr.s407525 | 2023 | | |
| Genetics | Mycobacterium tuberculosis Intra-Host Evolution Among Drug-Resistant Tuberculosis Patients Failing Treatment. | Perumal R, Khan A, Naidoo K, Ngema SL, Nandlal L, Padayatchi N, Dookie N. | Infect Drug Resist | 10.2147/idr.s408976 | 2023 | |
| Genetics | Insight into the drug-resistant characteristics and genetic diversity of multidrug-resistant Mycobacterium tuberculosis in China. | Song Z, Liu C, He W, Pei S, Liu D, Cao X, Wang Y, He P, Zhao B, Ou X, Xia H, Wang S, Zhao Y. | Microbiol Spectr | 10.1128/spectrum.01324-23 | 2023 | |
| ZNFX1 promotes AMPK-mediated autophagy against Mycobacterium tuberculosis by stabilizing Prkaa2 mRNA. | Liu H, Han Z, Chen L, Zhang J, Zhang Z, Chen Y, Liu F, Wang K, Liu J, Sai N, Zhou X, Zhou C, Hu S, Wen Q, Ma L. | JCI Insight | 10.1172/jci.insight.171850 | 2024 | | |
| Emergence of Canonical and Noncanonical Genomic Variants following In Vitro Exposure of Clinical Mycobacterium tuberculosis Strains to Bedaquiline or Clofazimine. | Ismail N, Ismail N, Dippenaar A, Warren RM, Peters RPH, Omar SV. | Antimicrob Agents Chemother | 10.1128/aac.01368-22 | 2023 | | |
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| HIV infection impairs the host response to Mycobacterium tuberculosis infection by altering surfactant protein D function in the human lung alveolar mucosa. | Akhter A, Moliva JI, Azad AK, Olmo-Fontanez A, Garcia-Vilanova A, Scordo JM, Gavrilin MA, Diaz PT, Endsley JJ, Weintraub ST, Schlesinger LS, Wewers MD, Torrelles JB. | Mucosal Immunol | 10.1016/j.mucimm.2023.12.003 | 2024 | | |
| Phylogeny | Traditional Medicinal Plants as a Source of Antituberculosis Drugs: A System Review. | Xu Y, Liang B, Kong C, Sun Z. | Biomed Res Int | 10.1155/2021/9910365 | 2021 | |
| Mycobacterium tuberculosis Adaptation in Response to Isoniazid Treatment in a Multi-Stress System That Mimics the Host Environment. | Yimcharoen M, Saikaew S, Wattananandkul U, Phunpae P, Intorasoot S, Tayapiwatana C, Butr-Indr B. | Antibiotics (Basel) | 10.3390/antibiotics12050852 | 2023 | | |
| Susceptibility pattern of Mycobacterium tuberculosis over a period of five years at Indus Hospital and Health Network, Karachi, Pakistan. | Khursheed N, Asif S, Bano S, Ali MM, Adnan F. | Pak J Med Sci | 10.12669/pjms.38.icon-2022.5778 | 2022 | | |
| Novel fusion protein REA induces robust prime protection against tuberculosis in mice. | Gurmessa SK, Choi HG, Back YW, Jiang Z, Pham TA, Choi S, Kim HJ. | NPJ Vaccines | 10.1038/s41541-025-01077-1 | 2025 | | |
| Synthesis, antimycobacterial evaluation, and molecular docking study of 1,2,4-triazole derivatives. | Xia MY, Cai YX, Chen JX, Zhao X, Dong HM, Yang ZC. | J Enzyme Inhib Med Chem | 10.1080/14756366.2023.2229070 | 2023 | | |
| Metabolism | Determining Minimum Inhibitory Concentrations in Liquid Cultures or on Solid Medium. | Wang Q, Boshoff HIM. | Methods Mol Biol | 10.1007/978-1-0716-1460-0_26 | 2021 | |
| Traditional uses, phytochemicals, and biological properties of Saba senegalensis. | Dang-I AY, Atta IO, Mbaadawu OH, Ibrahim S, Abugri J, Adu-Frimpong M. | Heliyon | 10.1016/j.heliyon.2024.e34934 | 2024 | | |
| Anti-Microbial Activity of Aliphatic Alcohols from Chinese Black Cardamom (Amomum tsao-ko) against Mycobacterium tuberculosis H37Rv | Lee SY, Shetye GS, Son SR, Lee H, Klein LL, Yoshihara JK, Ma R, Franzblau SG, Cho S, Jang DS. | Plants (Basel) | 10.3390/plants12010034 | 2022 | | |
| Quantification of Isoniazid-Heteroresistant Mycobacterium tuberculosis Using Droplet Digital PCR. | Zhang S, Chen X, Lin Z, Tan Y, Liang B, Pan Y, Huang M, Su B, Hu X, Xu Y, Li Q. | J Clin Microbiol | 10.1128/jcm.01884-22 | 2023 | | |
| Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria. | Junk L, Schmiedel VM, Guha S, Fischel K, Greb P, Vill K, Krisilia V, van Geelen L, Rumpel K, Kaur P, Krishnamurthy RV, Narayanan S, Shandil RK, Singh M, Kofink C, Mantoulidis A, Biber P, Gmaschitz G, Kazmaier U, Meinhart A, Leodolter J, Hoi D, Junker S, Morreale FE, Clausen T, Kalscheuer R, Weinstabl H, Boehmelt G. | Nat Commun | 10.1038/s41467-024-46218-7 | 2024 | | |
| Increased Susceptibility of Mycobacterium tuberculosis to Ethionamide by Expressing PPs-Induced Rv0560c. | Seo H, Kim S, Mahmud HA, Sultana OF, Lee Y, Yoon Y, Rahim MA, Jo S, Choi J, Lee S, Song HY. | Antibiotics (Basel) | 10.3390/antibiotics11101349 | 2022 | | |
| Pathogenicity | Anti-tubercular profile of new selenium-menadione conjugates against Mycobacterium tuberculosis H37Rv (ATCC 27294) strain and multidrug-resistant clinical isolates. | Ribeiro RCB, de Marins DB, Di Leo I, da Silva Gomes L, de Moraes MG, Abbadi BL, Villela AD, da Silva WF, da Silva LCRP, Machado P, Bizarro CV, Basso LA, Cristina de Moraes M, Ferreira VF, da Silva FC, Nascimento V. | Eur J Med Chem | 10.1016/j.ejmech.2020.112859 | 2021 | |
| Pathogenicity | Molecular hybridization approach for phenothiazine incorporated 1,2,3-triazole hybrids as promising antimicrobial agents: Design, synthesis, molecular docking and in silico ADME studies. | Reddyrajula R, Dalimba U, Madan Kumar S. | Eur J Med Chem | 10.1016/j.ejmech.2019.02.010 | 2019 | |
| Progress in the study of mefloquine as an antibiotic adjuvant for combination bacterial inhibition treatment. | Liang X, Liu Z, Wang Y, Zhang Y, Deng W, Liu Q, Lu Z, Li K, Chang Y, Wei L. | Front Cell Infect Microbiol | 10.3389/fcimb.2024.1470891 | 2024 | | |
| Novel hybrids of 1,2,3-triazole-benzoxazole: design, synthesis, and assessment of DprE1 enzyme inhibitors using fluorometric assay and computational analysis. | Singh M, Batt SM, Canales CSC, Pavan FR, Kumar SA, Akshatha HS, Bhagyalalitha M, Pujar KG, Bidye D, Pujar GV, Besra GS. | J Enzyme Inhib Med Chem | 10.1080/14756366.2024.2403744 | 2024 | | |
| Attenuated Cytokine-Induced Memory-Like Natural Killer Cell Responses to Mycobacterium tuberculosis in Tuberculosis Patients. | Liang C, Li S, Yuan J, Song Y, Ren W, Wang W, Shang Y, Tang S, Pang Y. | Infect Drug Resist | 10.2147/idr.s407742 | 2023 | | |
| Bactericidal and sterilizing activity of sudapyridine-clofazimine-TB47 combined with linezolid or pyrazinamide in a murine model of tuberculosis. | Yu W, Ju Y, Han X, Tian X, Ding J, Wang S, Hameed HMA, Gao Y, Li L, Li Y, Zhong N, Zhang T. | Antimicrob Agents Chemother | 10.1128/aac.00124-24 | 2024 | | |
| Pathogenicity | Development of Chitosan Particles Loaded with siRNA for Cystatin C to Control Intracellular Drug-Resistant Mycobacterium tuberculosis. | Pires D, Mandal M, Matos AI, Peres C, Catalao MJ, Azevedo-Pereira JM, Satchi-Fainaro R, Florindo HF, Anes E. | Antibiotics (Basel) | 10.3390/antibiotics12040729 | 2023 | |
| Discovery of pyrimidine-tethered benzothiazole derivatives as novel anti-tubercular agents towards multi- and extensively drug resistant Mycobacterium tuberculosis. | Hemeda LR, El Hassab MA, Abdelgawad MA, Khaleel EF, Abdel-Aziz MM, Binjubair FA, Al-Rashood ST, Eldehna WM, El-Ashrey MK. | J Enzyme Inhib Med Chem | 10.1080/14756366.2023.2250575 | 2023 | | |
| Molecular mechanism of a triazole-containing inhibitor of Mycobacterium tuberculosis DNA gyrase. | Gedeon A, Yab E, Dinut A, Sadowski E, Capton E, Dreneau A, Petit J, Gioia B, Piveteau C, Djaout K, Lecat E, Wehenkel AM, Gubellini F, Mechaly A, Alzari PM, Deprez B, Baulard A, Aubry A, Willand N, Petrella S. | iScience | 10.1016/j.isci.2024.110967 | 2024 | | |
| Pathogenicity | Drug-Resistant Characteristics, Genetic Diversity, and Transmission Dynamics of Rifampicin-Resistant Mycobacterium tuberculosis in Hunan, China, Revealed by Whole-Genome Sequencing. | He W, Tan Y, Liu C, Wang Y, He P, Song Z, Liu D, Zheng H, Ma A, Zhao B, Ou X, Xia H, Wang S, Zhao Y. | Microbiol Spectr | 10.1128/spectrum.01543-21 | 2022 | |
| An insight into the recent developments in anti-infective potential of indole and associated hybrids. | Mathada BS, Somappa SB. | J Mol Struct | 10.1016/j.molstruc.2022.132808 | 2022 | | |
| Spermine enhances the activity of anti-tuberculosis drugs. | Sao Emani C, Reiling N. | Microbiol Spectr | 10.1128/spectrum.03568-23 | 2024 | | |
| Evaluation Study of xMAP TIER Assay on a Microsphere-Based Platform for Detecting First-Line Anti-Tuberculosis Drug Resistance. | Ou X, Zhang Z, Zhao B, Song Z, Wang S, He W, Pei S, Liu D, Xing R, Xia H, Zhao Y. | Int J Environ Res Public Health | 10.3390/ijerph192417068 | 2022 | | |
| Pathogenicity | Liposomal Delivery of Saquinavir to Macrophages Overcomes Cathepsin Blockade by Mycobacterium tuberculosis and Helps Control the Phagosomal Replicative Niches. | Pires D, Mandal M, Pinho J, Catalao MJ, Almeida AJ, Azevedo-Pereira JM, Gaspar MM, Anes E. | Int J Mol Sci | 10.3390/ijms24021142 | 2023 | |
| Rifampin resistance among individuals with extrapulmonary tuberculosis: 4 years of experience from a reference laboratory. | Baghbanbashi S, Mousavi SMJ, Dabiri H, Hakemi-Vala M, Goudarzi H, Hamzehloo G, Amini S, Nasiri MJ. | New Microbes New Infect | 10.1016/j.nmni.2021.100841 | 2021 | | |
| Natural Polymorphisms in Mycobacterium tuberculosis Conferring Resistance to Delamanid in Drug-Naive Patients. | Reichmuth ML, Homke R, Zurcher K, Sander P, Avihingsanon A, Collantes J, Loiseau C, Borrell S, Reinhard M, Wilkinson RJ, Yotebieng M, Fenner L, Bottger EC, Gagneux S, Egger M, Keller PM. | Antimicrob Agents Chemother | 10.1128/aac.00513-20 | 2020 | | |
| Structure-Based Analysis of Semisynthetic Anti-TB Rufomycin Analogues. | Zhou B, Shetye G, Klein LL, Wolf NM, Lee H, McAlpine JB, Harris G, Chen SN, Suh JW, Cho SH, Franzblau SG, Abad-Zapatero C, Pauli GF. | J Nat Prod | 10.1021/acs.jnatprod.4c01266 | 2025 | | |
| Glycogen synthase kinase 3 inhibition controls Mycobacterium tuberculosis infection. | Pena-Diaz S, Chao JD, Rens C, Haghdadi H, Zheng X, Flanagan K, Ko M, Shapira T, Richter A, Maestre-Batlle D, Canseco JO, Gutierrez MG, Duc KD, Pelech S, Av-Gay Y. | iScience | 10.1016/j.isci.2024.110555 | 2024 | | |
| Synthesis, Anticancer and Antitubercular Properties of New Chalcones and Their Nitrogen-Containing Five-Membered Heterocyclic Hybrids Bearing Sulfonamide Moiety. | Castano LF, Quiroga J, Abonia R, Insuasty D, Vidal OM, Sena R, Rubio V, Puerto G, Nogueras M, Cobo J, Guzman J, Insuasty A, Insuasty B. | Int J Mol Sci | 10.3390/ijms232012589 | 2022 | | |
| Genetics | Co-resistance to isoniazid and second-line anti-tuberculosis drugs in isoniazid-resistant tuberculosis at a tertiary care hospital in Thailand. | Prommi A, Wongjarit K, Petsong S, Somsukpiroh U, Faksri K, Kawkitinarong K, Payungporn S, Rotcheewaphan S. | Microbiol Spectr | 10.1128/spectrum.03462-23 | 2024 | |
| (2Z)-3-Hydroxy-3-(4-R-Phenyl)-Prop-2-Enedithioic Acids as New Antituberculosis Compounds. | Pretelin-Castillo G, Silva Miranda M, Espitia C, Chavez-Santos RM, Suarez-Castro A, Chacon-Garcia L, Aguayo-Ortiz R, Martinez R. | Infect Drug Resist | 10.2147/idr.s328132 | 2021 | | |
| Resistance characteristics of culture-positive tuberculosis from 2015 to 2022 | Wang Z, Xu L, Guo T, Li L, Zhang Q, Liu J, Zu X, Zhao Z, Xue Y. | Front Public Health | 2025 | | ||
| Description, validation, and review of a decade of experience with a laboratory-developed PCR test for detection of Mycobacterium tuberculosis complex in pulmonary and extrapulmonary specimens. | Buckwalter SP, Connelly BJ, Louison LK, Kolesch JM, Herring SA, Woodliff ED, Bolster LaSalle CM, Grys TE, Deml SM, Wohlfiel SL, Steinmetz LK, Wengenack NL. | J Clin Tuberc Other Mycobact Dis | 10.1016/j.jctube.2022.100340 | 2022 | | |
| Mechanisms of a Mycobacterium tuberculosis Active Peptide. | Rao KU, Li P, Welinder C, Tenland E, Gourdon P, Sturegard E, Ho JCS, Godaly G. | Pharmaceutics | 10.3390/pharmaceutics15020540 | 2023 | | |
| Enzymology | Detection of Mycobacterium kansasii using a combination of loop-mediated isothermal amplification (LAMP) and lateral flow biosensors. | Chen C, Lu J, Long B, Rao Z, Gao Y, Wang W, Gao W, Yang J, Zhang S. | Int Microbiol | 10.1007/s10123-020-00143-z | 2021 | |
| Pathogenicity | Synthesis and Antibacterial Activity of Mefloquine-Based Analogs Against Sensitive and Resistant Mycobacterium tuberculosis Strains. | da Silva Araujo A, Moraes AM, Lourenco MCS, Pessoa CO, da Silva ET, de Souza MVN. | Curr Top Med Chem | 10.2174/1568026619666190304124952 | 2019 | |
| Genetics | The Emergence of Novel Spoligotypes of Highly Drug-Resistant Mycobacterium tuberculosis Isolates in Fujian, China. | Lin S, Wei S, Zhao Y, Dai Z, Lin J, Pang Y. | Infect Drug Resist | 10.2147/idr.s380950 | 2022 | |
| Advancements in the design and development of pyrazoline-based antimycobacterial agents: an update and future perspectives. | Rakshit G, Chakraborty S, Bhakta S, Jayaprakash V. | RSC Adv | 10.1039/d5ra03759j | 2025 | | |
| Establishing Compliance between Spectral, Colourimetric and Photometric Indicators in Resazurin Reduction Test. | Sychev AV, Lavrova AI, Dogonadze MZ, Postnikov EB. | Bioengineering (Basel) | 10.3390/bioengineering10080962 | 2023 | | |
| Detection of genomic mutations in katG and rpoB genes among multidrug-resistant Mycobacterium tuberculosis isolates from Tehran, Iran. | Motavaf B, Keshavarz N, Ghorbanian F, Firuzabadi S, Hosseini F, Zaker Bostanabad S. | New Microbes New Infect | 10.1016/j.nmni.2021.100879 | 2021 | | |
| SigH stress response mediates killing of Mycobacterium tuberculosis by activating nitronaphthofuran prodrugs via induction of Mrx2 expression. | Cioetto-Mazzabo L, Boldrin F, Beauvineau C, Speth M, Marina A, Namouchi A, Segafreddo G, Cimino M, Favre-Rochex S, Balasingham S, Trastoy B, Munier-Lehmann H, Griffiths G, Gicquel B, Guerin ME, Manganelli R, Alonso-Rodriguez N. | Nucleic Acids Res | 10.1093/nar/gkac1173 | 2023 | | |
| Pathogenicity | Persistence of Mycobacterium tuberculosis in response to infection burden and host-induced stressors. | Parbhoo T, Schurz H, Mouton JM, Sampson SL. | Front Cell Infect Microbiol | 10.3389/fcimb.2022.981827 | 2022 | |
| GenSeizer: a Multiplex PCR-Based Targeted Gene Sequencing Platform for Rapid and Accurate Identification of Major Mycobacterium Species. | Li B, Xu L, Guo Q, Chen J, Zhang Y, Huang W, Zhang Z, Han L, Xu X, Chu H. | J Clin Microbiol | 10.1128/jcm.00584-20 | 2021 | | |
| Latent Tuberculosis: A Promising New Compound to Treat Non-Replicating and Intramacrophagic Mycobacteria. | Campos DL, Demarqui FM, Solcia MC, de Souza PC, da Silva Maia PI, Deflon VM, Pavan FR. | Biomedicines | 10.3390/biomedicines10102398 | 2022 | | |
| Metabolism | Antimycobacterial activity of an anthracycline produced by an endophyte isolated from Amphipterygium adstringens. | Trenado-Uribe M, Silva-Miranda M, Rivero-Cruz JF, Rodriguez-Pena K, Espitia-Pinzon CI, Rodriguez-Sanoja R, Sanchez S. | Mol Biol Rep | 10.1007/s11033-018-4424-0 | 2018 | |
| Pathogenicity | Application of serial tests for Mycobacterium tuberculosis detection to active lung tuberculosis cases in Indonesia. | Sari NIP, Mertaniasih NM, Soedarsono, Maruyama F. | BMC Res Notes | 10.1186/s13104-019-4350-9 | 2019 | |
| Bioprotective and Functional Activities of Postbiotics From Lactic Acid Bacteria Derived From Artisanal Dairy Products. | Tariq A, Tahran MN, Ozturkoglu-Budak S. | Food Sci Nutr | 10.1002/fsn3.70647 | 2025 | | |
| Resistance against Membrane-Inserting MmpL3 Inhibitor through Upregulation of MmpL5 in Mycobacterium tuberculosis. | Li M, Nyantakyi SA, Go ML, Dick T. | Antimicrob Agents Chemother | 10.1128/aac.01100-20 | 2020 | | |
| Investigation of the Rv3065, Rv2942, Rv1258c, Rv1410c, and Rv2459 efflux pump genes expression among multidrug-resistant Mycobacterium tuberculosis clinical isolates. | Shahi F, Khosravi AD, Tabandeh MR, Salmanzadeh S. | Heliyon | 10.1016/j.heliyon.2021.e07566 | 2021 | | |
| Synthetic approaches to potent heterocyclic inhibitors of tuberculosis: A decade review. | Dasmahapatra U, Chanda K. | Front Pharmacol | 10.3389/fphar.2022.1021216 | 2022 | | |
| Fluoroquinolone Derivatives in the Treatment of Mycobacterium tuberculosis Infection. | Pais JP, Policarpo M, Pires D, Francisco AP, Madureira AM, Testa B, Anes E, Constantino L. | Pharmaceuticals (Basel) | 10.3390/ph15101213 | 2022 | | |
| Transcriptome | Clinical strains of Mycobacterium tuberculosis exhibit differential lipid metabolism-associated transcriptome changes in in vitro cholesterol and infection models. | Moopanar K, Nyide ANG, Senzani S, Mvubu NE. | Pathog Dis | 10.1093/femspd/ftac046 | 2023 | |
| Evaluation of the broth microdilution plate methodology for susceptibility testing of Mycobacterium tuberculosis in Peru. | Puyen ZM, Santos-Lazaro D, Vigo AN, Coronel J, Alarcon MJ, Cotrina VV, Moore DAJ. | BMC Infect Dis | 10.1186/s12879-022-07677-9 | 2022 | | |
| Clickable conjugates of bile acids and nucleosides: Synthesis, characterization, in vitro anticancer and antituberculosis studies. | Agarwal DS, Siva Krishna V, Sriram D, Yogeeswari P, Sakhuja R. | Steroids | 10.1016/j.steroids.2018.09.006 | 2018 | | |
| A novel multi-component protein vaccine ECP001 containing a protein polypeptide antigen nPstS1 riching in T-cell epitopes showed good immunogenicity and protection in mice. | Yu J, Fan X, Luan X, Wang R, Cao B, Qian C, Li G, Li M, Zhao X, Liu H, Wan K, Yuan X. | Front Immunol | 10.3389/fimmu.2023.1138818 | 2023 | | |
| Novel Organic Salts Based on Mefloquine: Synthesis, Solubility, Permeability, and In Vitro Activity against Mycobacterium tuberculosis. | Silva D, Lopes MVC, Petrovski Z, Santos MM, Santos JP, Yamada-Ogatta SF, Bispo MLF, de Souza MVN, Duarte ARC, Lourenco MCS, Goncalves RSB, Branco LC. | Molecules | 10.3390/molecules27165167 | 2022 | | |
| Impaired mitophagy induces antimicrobial responses in macrophages infected with Mycobacterium tuberculosis. | Lee J, Lee SA, Son SH, Choi JA, Nguyen TD, Kim J, Son D, Song CH. | Cell Biosci | 10.1186/s13578-023-01107-2 | 2023 | | |
| Rapid Detection of Mycobacterium tuberculosis in Pleural Fluid Using Resuscitation-Promoting Factor-Based Thin Layer Agar Culture Method. | Du F, Xing A, Li Z, Pan L, Jia H, Du B, Sun Q, Wei R, Liu Z, Zhang Z. | Front Microbiol | 10.3389/fmicb.2022.803521 | 2022 | | |
| Biological Properties, Health Benefits and Semisynthetic Derivatives of Edible Astraeus Mushrooms (Diplocystidiaceae): A Comprehensive Review. | Ung AT, Chen H. | Chem Biodivers | 10.1002/cbdv.202401295 | 2024 | | |
| Synthesis, Antibacterial Effects, and Toxicity of Licochalcone C. | Ozanique PR, Helena AL, Menezes RP, Goncalves DS, Santiago MB, Dilarri G, Sardi JCO, Ferreira H, Martins CHG, Regasini LO. | Pharmaceuticals (Basel) | 10.3390/ph17050634 | 2024 | | |
| Bedaquiline and clofazimine resistance in Mycobacterium tuberculosis: an in-vitro and in-silico data analysis. | Sonnenkalb L, Carter JJ, Spitaleri A, Iqbal Z, Hunt M, Malone KM, Utpatel C, Cirillo DM, Rodrigues C, Nilgiriwala KS, Fowler PW, Merker M, Niemann S, Comprehensive Resistance Prediction for Tuberculosis: an International Consortium. | Lancet Microbe | 10.1016/s2666-5247(23)00002-2 | 2023 | | |
| Semisynthetic modifications of antitubercular lanostane triterpenoids from Ganoderma. | Chinthanom P, Vichai V, Dokladda K, Sappan M, Thongpanchang C, Isaka M. | J Antibiot (Tokyo) | 10.1038/s41429-021-00422-5 | 2021 | | |
| Design, Synthesis and Antimicrobial Evaluation of New N-(1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)(hetero)aryl-2-carboxamides as Potential Inhibitors of Mycobacterial Leucyl-tRNA Synthetase. | Slechta P, Needle AA, Jand'ourek O, Paterova P, Konecna K, Barta P, Kunes J, Kubicek V, Dolezal M, Kucerova-Chlupacova M. | Int J Mol Sci | 10.3390/ijms24032951 | 2023 | | |
| Discovery of potent antimycobacterial agents targeting lumazine synthase (RibH) of Mycobacterium tuberculosis. | Singh M, Dhanwal A, Verma A, Augustin L, Kumari N, Chakraborti S, Agarwal N, Sriram D, Dey RJ. | Sci Rep | 10.1038/s41598-024-63051-6 | 2024 | | |
| Luteolin as a potential host-directed immunotherapy adjunct to isoniazid treatment of tuberculosis. | Singh DK, Tousif S, Bhaskar A, Devi A, Negi K, Moitra B, Ranganathan A, Dwivedi VP, Das G. | PLoS Pathog | 10.1371/journal.ppat.1009805 | 2021 | | |
| In silico repurposing of a Novobiocin derivative for activity against latency associated Mycobacterium tuberculosis drug target nicotinate-nucleotide adenylyl transferase (Rv2421c). | Cloete R, Shahbaaz M, Grobbelaar M, Sampson SL, Christoffels A. | PLoS One | 10.1371/journal.pone.0259348 | 2021 | | |
| Phenotypic and Genotypic Drug Susceptibility Assessment of Mycobacterium bovis Bacillus Calmette-Guérin Clinical Strains. | Sisco MC, Gomes da Silva M, Distasio de Carvalho L, Dias Campos CE, De Souza Caldas PC, Lopez B, Arguelles C, Carvalho AC, de Waard J, Suffys P, Silva Duarte R. | Infect Drug Resist | 10.2147/idr.s248096 | 2021 | | |
| Population pharmacokinetics and model-based dosing evaluation of bedaquiline in multidrug-resistant tuberculosis patients. | Shao G, Bao Z, Davies Forsman L, Paues J, Werngren J, Niward K, Schon T, Bruchfeld J, Alffenaar JW, Hu Y. | Front Pharmacol | 10.3389/fphar.2023.1022090 | 2023 | | |
| Design, synthesis, antitubercular and antiviral properties of new spirocyclic indole derivatives. | Cihan-Ustundag G, Naesens L, Satana D, Erkose-Genc G, Mataraci-Kara E, Capan G. | Monatsh Chem | 10.1007/s00706-019-02457-9 | 2019 | | |
| Mycobacterium tuberculosis Inhibitors Based on Arylated Quinoline Carboxylic Acid Backbones with Anti-Mtb Gyrase Activity. | Quimque MTJ, Go AD, Lim JAK, Vidar WS, Macabeo APG. | Int J Mol Sci | 10.3390/ijms241411632 | 2023 | | |
| Combined Locked Nucleic Acid Probes and High-Resolution Melting Curve Analysis for Detection of Rifampicin-Resistant Tuberculosis in Northern Thailand. | Thant YM, Saikaew S, Tharinjaroen CS, Phunpae P, Pongsararuk R, Preechasuth K, Butr-Indr B, Intorasoot S, Tragoolpua K, Chaiprasert A, Wattananandkul U. | Diagnostics (Basel) | 10.3390/diagnostics12102307 | 2022 | | |
| Heterologous prime-boost BCG with DNA vaccine expressing fusion antigens Rv2299c and Ag85A improves protective efficacy against Mycobacterium tuberculosis in mice. | Wu J, Hu Z, Lu SH, Fan XY. | Front Microbiol | 10.3389/fmicb.2022.927031 | 2022 | | |
| Synthesis, Biological Evaluation and Computational Studies of New Hydrazide Derivatives Containing 1,3,4-Oxadiazole as Antitubercular Agents. | Zampieri D, Fortuna S, Romano M, De Logu A, Cabiddu G, Sanna A, Mamolo MG. | Int J Mol Sci | 10.3390/ijms232315295 | 2022 | | |
| Brassicasterol with Dual Anti-Infective Properties against HSV-1 and Mycobacterium tuberculosis, and Cardiovascular Protective Effect: Nonclinical In Vitro and In Silico Assessments. | Hassan STS. | Biomedicines | 10.3390/biomedicines8050132 | 2020 | | |
| Design, synthesis and in vitro anti-tuberculosis activity of benzo[6,7]cyclohepta[1,2-b]pyridine-1,2,3-triazole derivatives. | Sajja Y, Vanguru S, Vulupala HR, Bantu R, Yogeswari P, Sriram D, Nagarapu L. | Bioorg Med Chem Lett | 10.1016/j.bmcl.2017.10.071 | 2017 | | |
| The Transcription Factor Rv1453 Regulates the Expression of qor and Confers Resistant to Clofazimine in Mycobacterium tuberculosis. | Li Y, Fu L, Zhang W, Chen X, Lu Y. | Infect Drug Resist | 10.2147/idr.s324043 | 2021 | | |
| Lipobiotin-capture magnetic bead assay for isolation, enrichment and detection of Mycobacterium tuberculosis from saliva. | Hansen J, Kolbe K, Konig IR, Scherliess R, Hellfritzsch M, Malm S, Muller-Loennies S, Zallet J, Hillemann D, Wiesmuller KH, Herzmann C, Brandenburg J, Reiling N. | PLoS One | 10.1371/journal.pone.0265554 | 2022 | | |
| Pathogenicity | Bis-spirochromanones as potent inhibitors of Mycobacterium tuberculosis: synthesis and biological evaluation. | Dongamanti A, Aamate VK, Devulapally MG, Gundu S, Balabadra S, Manga V, Yogeeswari P, Sriram D, Balasubramanian S. | Mol Divers | 10.1007/s11030-017-9779-y | 2017 | |
| Evaluation of Aptamer Fluorescence Microscopy in the Diagnosis of Pulmonary Tuberculosis. | Zheng R, Xu F, Huang X, Wang J, Feng Y, Huang J, Qin L. | Microbiol Spectr | 10.1128/spectrum.02602-21 | 2022 | | |
| Determination of critical concentration for drug susceptibility testing of Mycobacterium tuberculosis against para-aminosalicylic acid with clinical isolates with thyA, folC and dfrA mutations. | Wang W, Li S, Ge Q, Guo H, Shang Y, Ren W, Wang Y, Xue Z, Lu J, Pang Y. | Ann Clin Microbiol Antimicrob | 10.1186/s12941-022-00537-z | 2022 | | |
| Exploration of newly synthesized transition metal(II) complexes for infectious diseases. | Kumar B, Devi J, Dubey A, Kumar M. | Future Med Chem | 10.1080/17568919.2024.2389766 | 2024 | | |
| In vitro antimycobacterial activity of medicinal plants Lantana camara, Cryptolepis sanguinolenta, and Zanthoxylum leprieurii. | Tuyiringire N, Taremwa Mugisha I, Tusubira D, Munyampundu JP, Mambo Muvunyi C, Vander Heyden Y. | J Clin Tuberc Other Mycobact Dis | 10.1016/j.jctube.2022.100307 | 2022 | | |
| Pathogenicity | Isoniazid Resistance in Mycobacterium tuberculosis Is a Heterogeneous Phenotype Composed of Overlapping MIC Distributions with Different Underlying Resistance Mechanisms. | Ghodousi A, Tagliani E, Karunaratne E, Niemann S, Perera J, Koser CU, Cirillo DM. | Antimicrob Agents Chemother | 10.1128/aac.00092-19 | 2019 | |
| Genotypic Distribution and the Epidemiology of Multidrug Resistant Tuberculosis in Upper Northern Thailand. | Saikaew S, Thongprachum A, Pongsararuk R, Thanraka A, Kunyanone N, Chaiyasirinroje B, Luangsook P, Butr-Indr B, Phunpae P, Wattananandkul U. | Antibiotics (Basel) | 10.3390/antibiotics11121733 | 2022 | | |
| Antibody-Mediated LILRB2-Receptor Antagonism Induces Human Myeloid-Derived Suppressor Cells to Kill Mycobacterium tuberculosis. | Singh VK, Khan A, Xu Y, Mai S, Zhang L, Mishra A, Restrepo BI, Pan PY, Chen SH, Jagannath C. | Front Immunol | 10.3389/fimmu.2022.865503 | 2022 | | |
| Two New Dihydrosphingosine Analogs Against Mycobacterium tuberculosis Affect gltA1, lprQ, and rpsO Expression. | Penuelas-Urquides K, Bermudez de Leon M, Silva-Ramirez B, Castorena-Torres F, Molina-Salinas GM, Castro-Garza J, Becerril-Montes P, Del Olmo E, San Feliciano A, Gonzalez-Escalante LA, Villarreal-Trevino L, Said-Fernandez S. | Front Microbiol | 10.3389/fmicb.2021.742867 | 2021 | | |
| rpoB gene mutations in rifampin-resistant Mycobacterium tuberculosis isolates from rural areas of Zhejiang, China. | Zeng MC, Jia QJ, Tang LM. | J Int Med Res | 10.1177/0300060521997596 | 2021 | | |
| Pathogenicity | Antimycobacterial Activity of Laurinterol and Aplysin from Laurencia johnstonii. | Garcia-Davis S, Leal-Lopez K, Molina-Torres CA, Vera-Cabrera L, Diaz-Marrero AR, Fernandez JJ, Carranza-Rosales P, Viveros-Valdez E. | Mar Drugs | 10.3390/md18060287 | 2020 | |
| Metabolism | Rapid and visual detection of Mycobacterium tuberculosis complex using recombinase polymerase amplification combined with lateral flow strips. | Ma Q, Liu H, Ye F, Xiang G, Shan W, Xing W. | Mol Cell Probes | 10.1016/j.mcp.2017.08.004 | 2017 | |
| In Vitro Profiling of Antitubercular Compounds by Rapid, Efficient, and Nondestructive Assays Using Autoluminescent Mycobacterium tuberculosis. | Shetye GS, Choi KB, Kim CY, Franzblau SG, Cho S. | Antimicrob Agents Chemother | 10.1128/aac.00282-21 | 2021 | | |
| Pathogenicity | Activity of Riminophenazines against Mycobacterium tuberculosis: A Review of Studies that Might be Contenders for Use as Antituberculosis Agents. | Bvumbi MV. | ChemMedChem | 10.1002/cmdc.202000580 | 2020 | |
| Metabolism | Mycobacterial acyl carrier protein suppresses TFEB activation and upregulates miR-155 to inhibit host defense. | Paik S, Kim KT, Kim IS, Kim YJ, Kim HJ, Choi S, Kim HJ, Jo EK. | Front Immunol | 10.3389/fimmu.2022.946929 | 2022 | |
| Copper mediated one-pot synthesis of quinazolinones and exploration of piperazine linked quinazoline derivatives as anti-mycobacterial agents. | Malasala S, Gour J, Ahmad MN, Gatadi S, Shukla M, Kaul G, Dasgupta A, Madhavi YV, Chopra S, Nanduri S. | RSC Adv | 10.1039/d0ra08644d | 2020 | | |
| Para-aminosalicylic acid increases the susceptibility to isoniazid in clinical isolates of Mycobacterium tuberculosis. | Zhang T, Jiang G, Wen S, Huo F, Wang F, Huang H, Pang Y. | Infect Drug Resist | 10.2147/idr.s200697 | 2019 | | |
| Investigation of Copaifera genus as a new source of antimycobaterial agents. | Alves JA, Abrao F, da Silva Moraes T, Damasceno JL, Dos Santos Moraes MF, Sola Veneziani RC, Ambrosio SR, Bastos JK, Dantas Miranda ML, Gomes Martins CH. | Future Sci OA | 10.2144/fsoa-2020-0018 | 2020 | | |
| Pathogenicity | Luteolin-mediated Kv1.3 K+ channel inhibition augments BCG vaccine efficacy against tuberculosis by promoting central memory T cell responses in mice. | Singh DK, Dwivedi VP, Singh SP, Kumari A, Sharma SK, Ranganathan A, Kaer LV, Das G. | PLoS Pathog | 10.1371/journal.ppat.1008887 | 2020 | |
| A Mycobacterium tuberculosis NBTI DNA Gyrase Inhibitor Is Active against Mycobacterium abscessus. | Ganapathy US, Del Rio RG, Cacho-Izquierdo M, Ortega F, Lelievre J, Barros-Aguirre D, Aragaw WW, Zimmerman MD, Lindman M, Dartois V, Gengenbacher M, Dick T. | Antimicrob Agents Chemother | 10.1128/aac.01514-21 | 2021 | | |
| Pathogenicity | Three new platinum complexes containing fluoroquinolones and DMSO: Cytotoxicity and evaluation against drug-resistant tuberculosis. | de Oliveira LP, Carneiro ZA, Ribeiro CM, Lima MF, Paixao DA, Pivatto M, de Souza MVN, Teixeira LR, Lopes CD, de Albuquerque S, Pavan FR, Guerra W. | J Inorg Biochem | 10.1016/j.jinorgbio.2018.03.010 | 2018 | |
| Pathogenicity | High prevalence of phenotypic pyrazinamide resistance and its association with pncA gene mutations in Mycobacterium tuberculosis isolates from Uganda. | Naluyange R, Mboowa G, Komakech K, Semugenze D, Kateete DP, Ssengooba W. | PLoS One | 10.1371/journal.pone.0232543 | 2020 | |
| Pathogenicity | A Microbiological, Toxicological, and Biochemical Study of the Effects of Fucoxanthin, a Marine Carotenoid, on Mycobacterium tuberculosis and the Enzymes Implicated in Its Cell Wall: A Link Between Mycobacterial Infection and Autoimmune Diseases. | Sudomova M, Shariati MA, Echeverria J, Berindan-Neagoe I, Nabavi SM, Hassan STS. | Mar Drugs | 10.3390/md17110641 | 2019 | |
| The human proton pump inhibitors inhibit Mycobacterium tuberculosis rifampicin efflux and macrophage-induced rifampicin tolerance. | Lake MA, Adams KN, Nie F, Fowler E, Verma AK, Dei S, Teodori E, Sherman DR, Edelstein PH, Spring DR, Troll M, Ramakrishnan L. | Proc Natl Acad Sci U S A | 10.1073/pnas.2215512120 | 2023 | | |
| Identification of benzothiazones containing a hexahydropyrrolo[3,4-c]pyrrol moiety as antitubercular agents against MDR-MTB. | Ma X, Han B, Wang A, Yang L, Huang M, Chowdhury K, Gu J, Zhang K, Lv K. | RSC Adv | 10.1039/d0ra00750a | 2020 | | |
| Metabolism | Rationally Designed Novel Phenyloxazoline Synthase Inhibitors: Chemical Synthesis and Biological Evaluation to Accelerate the Discovery of New Antimycobacterial Antibiotics. | Shyam M, Bhattacharje G, Daniel C, Kumar A, Yadav P, Mukherjee P, Singh S, Das AK, Narender T, Singh A, Jayaprakash V, Bhakta S. | Molecules | 10.3390/molecules28248115 | 2023 | |
| Potential Efficacy of beta-Amyrin Targeting Mycobacterial Universal Stress Protein by In Vitro and In Silico Approach. | Beg MA, Shivangi, Afzal O, Akhtar MS, Altamimi ASA, Hussain A, Imam MA, Ahmad MN, Chopra S, Athar F. | Molecules | 10.3390/molecules27144581 | 2022 | | |
| Evaluation of the effect of Pulicaria gnaphalodes and Perovskia abrotanoides essential oil extracts against Mycobacterium tuberculosis strains. | Hozoorbakhsh F, Esfahani BN, Moghim S, Asghari G. | Adv Biomed Res | 10.4103/2277-9175.180991 | 2016 | | |
| DNA Methyltransferase HsdM Induce Drug Resistance on Mycobacterium tuberculosis via Multiple Effects. | Chu H, Hu Y, Zhang B, Sun Z, Zhu B. | Antibiotics (Basel) | 10.3390/antibiotics10121544 | 2021 | | |
| Characterization of the most common embCAB gene mutations associated with ethambutol resistance in Mycobacterium tuberculosis isolates from Iran. | Khosravi AD, Sirous M, Abdi M, Ahmadkhosravi N. | Infect Drug Resist | 10.2147/idr.s196800 | 2019 | | |
| GaMF1.39's antibiotic efficacy and its enhanced antitubercular activity in combination with clofazimine, Telacebec, ND-011992, or TBAJ-876. | Ragunathan P, Shuyi Ng P, Singh S, Poh WH, Litty D, Kalia NP, Larsson S, Harikishore A, Rice SA, Ingham PW, Muller V, Moraski G, Miller MJ, Dick T, Pethe K, Gruber G. | Microbiol Spectr | 10.1128/spectrum.02282-23 | 2023 | | |
| Building Optimal Three-Drug Combination Chemotherapy Regimens To Eradicate Mycobacterium tuberculosis in Its Slow-Growth Acid Phase. | Kim S, Yamada WM, Duncanson B, Nole J, Rogers S, Parker S, Bacci M, Mtchedlidze N, Peloquin CA, Louie A, Schmidt S, Drusano GL, Neely MN. | Antimicrob Agents Chemother | 10.1128/aac.00693-21 | 2021 | | |
| Drug resistance characteristics of Mycobacterium tuberculosis isolates obtained between 2018 and 2020 in Sichuan, China. | Zhou R, Zheng T, Luo D, Zhu M, Li Q, Xu Y, Wang D, Luo J, Zeng C, Wei G, Tang M, Zhao X, Zhou M, Zuo H, Pei X. | Epidemiol Infect | 10.1017/s0950268822000127 | 2022 | | |
| In Vitro Activities of Enantiopure and Racemic 1'-Acetoxychavicol Acetate against Clinical Isolates of Mycobacterium tuberculosis. | Warit S, Rukseree K, Prammananan T, Hongmanee P, Billamas P, Jaitrong S, Chaiprasert A, Jaki BU, Pauli GF, Franzblau SG, Palittapongarnpim P. | Sci Pharm | 10.3390/scipharm85030032 | 2017 | | |
| Ancient and recent differences in the intrinsic susceptibility of Mycobacterium tuberculosis complex to pretomanid. | Bateson A, Ortiz Canseco J, McHugh TD, Witney AA, Feuerriegel S, Merker M, Kohl TA, Utpatel C, Niemann S, Andres S, Kranzer K, Maurer FP, Ghodousi A, Borroni E, Cirillo DM, Wijkander M, Toro JC, Groenheit R, Werngren J, Machado D, Viveiros M, Warren RM, Sirgel F, Dippenaar A, Koser CU, Sun E, Timm J. | J Antimicrob Chemother | 10.1093/jac/dkac070 | 2022 | | |
| Hollow-fibre system model of tuberculosis reproducibility and performance specifications for best practice in drug and combination therapy development. | Gumbo T, Srivastava S, Deshpande D, Pasipanodya JG, Berg A, Romero K, Hermann D, Hanna D. | J Antimicrob Chemother | 10.1093/jac/dkad029 | 2023 | | |
| Elevated Natural Killer Cell-Mediated Cytotoxicity Is Associated with Cavity Formation in Pulmonary Tuberculosis Patients. | Li S, Wang D, Wei P, Liu R, Guo J, Yang B, Zhang H, Lu J, Gao M, Pang Y. | J Immunol Res | 10.1155/2021/7925903 | 2021 | | |
| Analysis on Drug-Resistance-Associated Mutations among Multidrug-Resistant Mycobacterium tuberculosis Isolates in China. | Jia H, Xu Y, Sun Z. | Antibiotics (Basel) | 10.3390/antibiotics10111367 | 2021 | | |
| A Label-Based Polymer Nanoparticles Biosensor Combined with Loop-Mediated Isothermal Amplification for Rapid, Sensitive, and Highly Specific Identification of Brucella abortus. | Yang X, Wang Y, Liu Y, Huang J, Tan Q, Ying X, Hu Y, Li S. | Front Bioeng Biotechnol | 10.3389/fbioe.2021.758564 | 2021 | | |
| Dose Fractionation of Moxifloxacin for Treatment of Tuberculosis: Impact of Dosing Interval and Elimination Half-Life on Microbial Kill and Resistance Suppression. | Drusano GL, Rogers S, Brown D, Peloquin CA, Neely M, Yamada W, Kim S, Almoslem M, Schmidt S, Louie A. | Antimicrob Agents Chemother | 10.1128/aac.02533-20 | 2021 | | |
| Pathogenicity | The Protective Action of Piperlongumine Against Mycobacterial Pulmonary Tuberculosis in Its Mitigation of Inflammation and Macrophage Infiltration in Male BALB/c Mice. | Lu N, Yang Y, Li X, Li J, Cheng J, Lv Z, Du Y. | J Vet Res | 10.2478/jvetres-2021-0061 | 2021 | |
| Phylogeny | Occurrence and risk factors of nontuberculous mycobacteria in tuberculosis-suspected patients in the north of Iran. | Shafipour M, Shirzad-Aski H, Ghaemi EA, Sohrabi A, Taziki M, Kochkaksaraei MB, Rahimi S. | Iran J Microbiol | 10.18502/ijm.v13i2.5980 | 2021 | |
| NSC19723, a Thiacetazone-Like Benzaldehyde Thiosemicarbazone Improves the Efficacy of TB Drugs In Vitro and In Vivo. | Singh P, Rawat S, Agrahari AK, Singh M, Chugh S, Gurcha S, Singh A, Abrahams K, Besra GS, Asthana S, Rawat DS, Singh R. | Microbiol Spectr | 10.1128/spectrum.02592-22 | 2022 | | |
| High-resolution melt curve analysis for rapid detection of rifampicin resistance in Mycobacterium tuberculosis: a single-centre study in Iran. | Arefzadeh S, Azimi T, Nasiri MJ, Nikpor Z, Dabiri H, Doustdar F, Goudarzi H, Allahyartorkaman M. | New Microbes New Infect | 10.1016/j.nmni.2020.100665 | 2020 | | |
| Effect of specimen processing, growth supplement, and different metabolic population on Mycobacterium tuberculosis laboratory diagnosis. | Srivastava S, Chapagain M, Gumbo T. | PLoS One | 10.1371/journal.pone.0230927 | 2020 | | |
| Antibacterial Activity of Isobavachalcone (IBC) Is Associated with Membrane Disruption. | Assis LR, Theodoro RDS, Costa MBS, Nascentes JAS, Rocha MDD, Bessa MAS, Menezes RP, Dilarri G, Hypolito GB, Santos VRD, Duque C, Ferreira H, Martins CHG, Regasini LO. | Membranes (Basel) | 10.3390/membranes12030269 | 2022 | | |
| Antimycobacterial potentials of quercetin and rutin against Mycobacterium tuberculosis H37Rv. | Sasikumar K, Ghosh AR, Dusthackeer A. | 3 Biotech | 10.1007/s13205-018-1450-5 | 2018 | | |
| Treatment of Clinically Important Bacteria With Cold Atmospheric Plasma. | Ding R, Song J, Huang X, Tan L, Rao X, Yang Y. | Microb Biotechnol | 10.1111/1751-7915.70219 | 2025 | | |
| Pathogenicity | Accuracy of a reverse dot blot hybridization assay for simultaneous detection of the resistance of four anti-tuberculosis drugs in Mycobacterium tuberculosis isolated from China. | Wan L, Guo Q, Wei JH, Liu HC, Li MC, Jiang Y, Zhao LL, Zhao XQ, Liu ZG, Wan KL, Li GL, Guan CX. | Infect Dis Poverty | 10.1186/s40249-020-00652-z | 2020 | |
| Pathogenicity | In Vitro and In Vivo Activities of Contezolid (MRX-I) against Mycobacterium tuberculosis. | Shoen C, DeStefano M, Hafkin B, Cynamon M. | Antimicrob Agents Chemother | 10.1128/aac.00493-18 | 2018 | |
| Pathogenicity | Anti-Tuberculosis Activity of Pediococcus acidilactici Isolated from Young Radish Kimchi against Mycobacterium tuberculosis. | Yoon Y, Seo H, Kim S, Lee Y, Rahim MA, Lee S, Song HY. | J Microbiol Biotechnol | 10.4014/jmb.2107.07044 | 2021 | |
| Therapeutic potential of oxadiazole or furadiazole containing compounds. | Siwach A, Verma PK. | BMC Chem | 10.1186/s13065-020-00721-2 | 2020 | | |
| Genetics | Detection of Beijing strains of MDR M. tuberculosis and their association with drug resistance mutations in katG, rpoB, and embB genes. | Gupta A, Sinha P, Nema V, Gupta PK, Chakraborty P, Kulkarni S, Rastogi N, Anupurba S. | BMC Infect Dis | 10.1186/s12879-020-05479-5 | 2020 | |
| Pathogenicity | Modulation of Cystatin C in Human Macrophages Improves Anti-Mycobacterial Immune Responses to Mycobacterium tuberculosis Infection and Coinfection With HIV. | Pires D, Calado M, Velez T, Mandal M, Catalao MJ, Neyrolles O, Lugo-Villarino G, Verollet C, Azevedo-Pereira JM, Anes E. | Front Immunol | 10.3389/fimmu.2021.742822 | 2021 | |
| Synthesis, Activity, Toxicity, and In Silico Studies of New Antimycobacterial N-Alkyl Nitrobenzamides. | Pais JP, Antoniuk O, Pires D, Delgado T, Fortuna A, Costa PJ, Anes E, Constantino L. | Pharmaceuticals (Basel) | 10.3390/ph17050608 | 2024 | | |
| Evaluation of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase (DAHPS) as a Vulnerable Target in Mycobacterium tuberculosis. | Galina L, Hopf FSM, Abbadi BL, Sperotto NDM, Czeczot AM, Duque-Villegas MA, Perello MA, Matter LB, de Souza EV, Parish T, Machado P, Basso LA, Bizarro CV. | Microbiol Spectr | 10.1128/spectrum.00728-22 | 2022 | | |
| Development of New Drugs to Treat Tuberculosis Based on the Dinitrobenzamide Scaffold. | Delgado T, Pais JP, Pires D, Estrada FGA, Guedes RC, Anes E, Constantino L. | Pharmaceuticals (Basel) | 10.3390/ph17050559 | 2024 | | |
| Exploring Benzo[h]chromene Derivatives as Agents against Protozoal and Mycobacterial Infections. | Pertino MW, F de la Torre A, Schmeda-Hirschmann G, Vega Gomez C, Rolon M, Coronel C, Rojas de Arias A, Molina-Torres CA, Vera-Cabrera L, Viveros-Valdez E. | Pharmaceuticals (Basel) | 10.3390/ph17101375 | 2024 | | |
| A Nanostructured Lipid System to Improve the Oral Bioavailability of Ruthenium(II) Complexes for the Treatment of Infections Caused by Mycobacterium tuberculosis. | da Silva PB, de Freitas ES, Solcia MC, de Souza PC, da Silva MM, Batista AA, Eismann CE, Rolisola AMCM, Menegario AA, Cardoso RF, Chorilli M, Pavan FR. | Front Microbiol | 10.3389/fmicb.2018.02930 | 2018 | | |
| Moxifloxacin Activates the SOS Response in Mycobacterium tuberculosis in a Dose- and Time-Dependent Manner. | Iacobino A, Piccaro G, Pardini M, Fattorini L, Giannoni F. | Microorganisms | 10.3390/microorganisms9020255 | 2021 | | |
| Phylogeny | Culture-Free Enumeration of Mycobacterium tuberculosis in Mouse Tissues Using the Molecular Bacterial Load Assay for Preclinical Drug Development. | Evangelopoulos D, Shoen CM, Honeyborne I, Clark S, Williams A, Mukamolova GV, Cynamon MH, McHugh TD. | Microorganisms | 10.3390/microorganisms10020460 | 2022 | |
| Whole genome sequencing-based drug resistance predictions of multidrug-resistant Mycobacterium tuberculosis isolates from Tanzania. | Mbelele PM, Utpatel C, Sauli E, Mpolya EA, Mutayoba BK, Barilar I, Dreyer V, Merker M, Sariko ML, Swema BM, Mmbaga BT, Gratz J, Addo KK, Pletschette M, Niemann S, Houpt ER, Mpagama SG, Heysell SK. | JAC Antimicrob Resist | 10.1093/jacamr/dlac042 | 2022 | | |
| Benzoic Acid Derivatives as Prodrugs for the Treatment of Tuberculosis. | Pais JP, Magalhaes M, Antoniuk O, Barbosa I, Freire R, Pires D, Valente E, Testa B, Anes E, Constantino L. | Pharmaceuticals (Basel) | 10.3390/ph15091118 | 2022 | | |
| Pathogenicity | Detection of low-frequency resistance-mediating SNPs in next-generation sequencing data of Mycobacterium tuberculosis complex strains with binoSNP. | Dreyer V, Utpatel C, Kohl TA, Barilar I, Groschel MI, Feuerriegel S, Niemann S. | Sci Rep | 10.1038/s41598-020-64708-8 | 2020 | |
| Enhancement in anti-tubercular activity of indole based thiosemicarbazones on complexation with copper(I) and silver(I) halides: Structure elucidation, evaluation and molecular modelling. | Khan A, Jasinski JP, Smolenski VA, Hotchkiss EP, Kelley PT, Shalit ZA, Kaur M, Paul K, Sharma R. | Bioorg Chem | 10.1016/j.bioorg.2018.06.027 | 2018 | | |
| Isolation of bioactive compounds from medicinal plants used in traditional medicine: Rautandiol B, a potential lead compound against Plasmodium falciparum. | Dawurung CJ, Nguyen MTH, Pengon J, Dokladda K, Bunyong R, Rattanajak R, Kamchonwongpaisan S, Nguyen PTM, Pyne SG. | BMC Complement Med Ther | 10.1186/s12906-021-03406-y | 2021 | | |
| Pathogenicity | Design, development of new synthetic methodology, and biological evaluation of substituted quinolines as new anti-tubercular leads. | Tanwar B, Kumar A, Yogeeswari P, Sriram D, Chakraborti AK. | Bioorg Med Chem Lett | 10.1016/j.bmcl.2016.10.082 | 2016 | |
| QMAC-DST for Rapid Detection of Drug Resistance in Pulmonary Tuberculosis Patients: A Multicenter Pre-Post Comparative Study. | Kwak N, Lee S, Kim S, Song E, Yim JJ, Shim TS, Jeon D, Jhun BW, Seok KH, Kim S, Kwon S, Mok J. | J Clin Med | 10.3390/jcm13102941 | 2024 | | |
| A data compendium associating the genomes of 12,289 Mycobacterium tuberculosis isolates with quantitative resistance phenotypes to 13 antibiotics. | The CRyPTIC Consortium. | PLoS Biol | 10.1371/journal.pbio.3001721 | 2022 | | |
| Role of Hydrogen Peroxide Vapor (HPV) for the Disinfection of Hospital Surfaces Contaminated by Multiresistant Bacteria. | Totaro M, Casini B, Profeti S, Tuvo B, Privitera G, Baggiani A. | Pathogens | 10.3390/pathogens9050408 | 2020 | | |
| Nitrobenzoates and Nitrothiobenzoates with Activity against M. tuberculosis. | Pais JP, Antoniuk O, Freire R, Pires D, Valente E, Anes E, Constantino L. | Microorganisms | 10.3390/microorganisms11040969 | 2023 | | |
| Enzymology | Validation of a Multiplex Real-Time PCR Assay for Detection of Mycobacterium spp., Mycobacterium tuberculosis Complex, and Mycobacterium avium Complex Directly from Clinical Samples by Use of the BD Max Open System. | Rocchetti TT, Silbert S, Gostnell A, Kubasek C, Widen R. | J Clin Microbiol | 10.1128/jcm.00241-16 | 2016 | |
| Enzymology | Molecular Bacterial Load Assay Concurs with Culture on NaOH-Induced Loss of Mycobacterium tuberculosis Viability. | Mtafya B, Sabiiti W, Sabi I, John J, Sichone E, Ntinginya NE, Gillespie SH. | J Clin Microbiol | 10.1128/jcm.01992-18 | 2019 | |
| Predominance of Escherichia-Shigella in Gut Microbiome and Its Potential Correlation with Elevated Level of Plasma Tumor Necrosis Factor Alpha in Patients with Tuberculous Meningitis. | Li S, Guo J, Liu R, Zhang F, Wen S, Liu Y, Ren W, Zhang X, Shang Y, Gao M, Lu J, Pang Y. | Microbiol Spectr | 10.1128/spectrum.01926-22 | 2022 | | |
| The relationship between embb306 and embb406 mutations and ethambutol resistant in Mycobacterium tuberculosis isolated from patiens in west of Iran. | Mohammadi B, Mohajeri P, Rouhi S, Ramazanzadeh R. | Med J Islam Repub Iran | 10.14196/mjiri.32.117 | 2018 | | |
| Premature termination of transcription is shaped by Rho and translated uORFS in Mycobacterium tuberculosis. | D'Halluin A, Polgar P, Kipkorir T, Patel Z, Cortes T, Arnvig KB. | iScience | 10.1016/j.isci.2023.106465 | 2023 | | |
| Isoxazole carboxylic acid methyl ester-based urea and thiourea derivatives as promising antitubercular agents. | Sahoo SK, Ommi O, Maddipatla S, Singh P, Ahmad MN, Kaul G, Nanduri S, Dasgupta A, Chopra S, Yaddanapudi VM. | Mol Divers | 10.1007/s11030-022-10543-0 | 2023 | | |
| Activation of transcription factor CREB in human macrophages by Mycobacterium tuberculosis promotes bacterial survival, reduces NF-kB nuclear transit and limits phagolysosome fusion by reduced necroptotic signaling. | Leopold Wager CM, Bonifacio JR, Simper J, Naoun AA, Arnett E, Schlesinger LS. | PLoS Pathog | 10.1371/journal.ppat.1011297 | 2023 | | |
| A novel class of antimicrobial drugs selectively targets a Mycobacterium tuberculosis PE-PGRS protein. | Seo H, Kim S, Mahmud HA, Islam MI, Yoon Y, Cho HD, Nam KW, Choi J, Gil YS, Lee BE, Song HY. | PLoS Biol | 10.1371/journal.pbio.3001648 | 2022 | | |
| Pathogenicity | Diphenyleneiodonium chloride (DPIC) displays broad-spectrum bactericidal activity. | Pandey M, Singh AK, Thakare R, Talwar S, Karaulia P, Dasgupta A, Chopra S, Pandey AK. | Sci Rep | 10.1038/s41598-017-11575-5 | 2017 | |
| Enzymology | Mycobacterium tuberculosis PanD Structure-Function Analysis and Identification of a Potent Pyrazinoic Acid-Derived Enzyme Inhibitor. | Ragunathan P, Cole M, Latka C, Aragaw WW, Hegde P, Shin J, Subramanian Manimekalai MS, Rishikesan S, Aldrich CC, Dick T, Gruber G. | ACS Chem Biol | 10.1021/acschembio.1c00131 | 2021 | |
| Activity of Clofazimine and TBI-166 against Mycobacterium tuberculosis in Different Administration Intervals in Mouse Tuberculosis Models. | Zhu H, Fu L, Wang B, Chen X, Zhao J, Huang H, Lu Y. | Antimicrob Agents Chemother | 10.1128/aac.02164-20 | 2021 | | |
| Developing New Drugs for Mycobacterium tuberculosis Therapy: What Information Do We Get from Preclinical Animal Models? | Drusano GL, Duncanson B, Scanga CA, Kim S, Schmidt S, Neely MN, Yamada WM, Vicchiarelli M, Peloquin CA, Louie A. | Antimicrob Agents Chemother | 10.1128/aac.01376-20 | 2020 | | |
| Characteristics of Drug-sensitive and Drug-resistant Tuberculosis Cases among Adults at Tuberculosis Referral Hospitals in Indonesia. | Burhan E, Karyana M, Karuniawati A, Kusmiati T, Wibisono BH, Handayani D, Riyanto BS, Sajinadiyasa IGK, Sinaga BYM, Djaharuddin I, Indah Sugiyono R, Susanto NH, Diana A, Kosasih H, Lokida D, Siswanto, Neal A, Lau CY, Siddiqui S. | Am J Trop Med Hyg | 10.4269/ajtmh.22-0142 | 2022 | | |
| Pathogenicity | Discovery of a novel type IIb RelBE toxin-antitoxin system in Mycobacterium tuberculosis defined by co-regulation with an antisense RNA. | Dawson CC, Cummings JE, Starkey JM, Slayden RA. | Mol Microbiol | 10.1111/mmi.14917 | 2022 | |
| Naphthoquinone Derivatives as Scaffold to Develop New Drugs for Tuberculosis Treatment. | Halicki PCB, Ferreira LA, De Moura KCG, Carneiro PF, Del Rio KP, Carvalho TDSC, Pinto MDCFR, da Silva PEA, Ramos DF. | Front Microbiol | 10.3389/fmicb.2018.00673 | 2018 | | |
| Characterization of Drug-Resistant Lipid-Dependent Differentially Detectable Mycobacterium tuberculosis. | Mesman AW, Baek SH, Huang CC, Kim YM, Cho SN, Ioerger TR, Barreda NN, Calderon R, Sassetti CM, Murray MB. | J Clin Med | 10.3390/jcm10153249 | 2021 | | |
| Patterns of rpoC Mutations in Drug-Resistant Mycobacterium tuberculosis Isolated from Patients in South Korea. | Yun YJ, Lee JS, Yoo JC, Cho E, Park D, Kook YH, Lee KH. | Tuberc Respir Dis (Seoul) | 10.4046/trd.2017.0042 | 2018 | | |
| Antimicrobial Susceptibility Testing Using the MYCO Test System and MIC Distribution of 8 Drugs against Clinical Isolates of Nontuberculous Mycobacteria from Shanghai. | Ying R, Yang J, Wu X, Yu F, Sha W. | Microbiol Spectr | 10.1128/spectrum.02549-22 | 2023 | | |
| Antimycobacterial Activity of Solid Lipid Microparticles Loaded with Ursolic Acid and Oleanolic Acid: In Vitro, In Vivo, and Toxicity Assessments. | Saini V, Mata Espinosa D, Pandey A, Dighe V, Barrios Payan J, Prasad Myneedu V, Valdez Zarate I, Rajani DP, Anande LD, Hernandez Pando R, Srivastava R. | Microorganisms | 10.3390/microorganisms12112140 | 2024 | | |
| Pathogenicity | 8-Mercaptoguanine-based inhibitors of Mycobacterium tuberculosis dihydroneopterin aldolase: synthesis, in vitro inhibition and docking studies. | Czeczot AM, Roth CD, Ducati RG, Pissinate K, Rambo RS, Timmers LFSM, Abbadi BL, Macchi FS, Pestana VZ, Basso LA, Machado P, Bizarro CV. | J Enzyme Inhib Med Chem | 10.1080/14756366.2021.1900157 | 2021 | |
| Pathogenicity | Characterization of mutations in the rpoB gene conferring rifampicin resistance in Mycobacterium tuberculosis complex isolated from lymph nodes of slaughtered cattle from South Africa. | Bhembe NL, Green E. | Braz J Microbiol | 10.1007/s42770-020-00356-4 | 2020 | |
| Pathogenicity | Synthesis and biological activity of furoxan derivatives against Mycobacterium tuberculosis. | Fernandes GFDS, de Souza PC, Marino LB, Chegaev K, Guglielmo S, Lazzarato L, Fruttero R, Chung MC, Pavan FR, Dos Santos JL. | Eur J Med Chem | 10.1016/j.ejmech.2016.07.039 | 2016 | |
| The Role of Next-Generation Sequencing (NGS) in the Management of Tuberculosis: Practical Review for Implementation in Routine. | Beviere M, Reissier S, Penven M, Dejoies L, Guerin F, Cattoir V, Piau C. | Pathogens | 10.3390/pathogens12080978 | 2023 | | |
| Pathogenicity | Pyrazinamide Is Active against Mycobacterium tuberculosis Cultures at Neutral pH and Low Temperature. | den Hertog AL, Menting S, Pfeltz R, Warns M, Siddiqi SH, Anthony RM. | Antimicrob Agents Chemother | 10.1128/aac.00654-16 | 2016 | |
| Antimycobacterial, Enzyme Inhibition, and Molecular Interaction Studies of Psoromic Acid in Mycobacterium tuberculosis: Efficacy and Safety Investigations. | Hassan STS, Sudomova M, Berchova-Bimova K, Gowrishankar S, Rengasamy KRR. | J Clin Med | 10.3390/jcm7080226 | 2018 | | |
| Pathogenicity | In Vitro Susceptibility of Mycobacterium tuberculosis to Amikacin, Kanamycin, and Capreomycin. | Dijkstra JA, van der Laan T, Akkerman OW, Bolhuis MS, de Lange WCM, Kosterink JGW, van der Werf TS, Alffenaar JWC, van Soolingen D. | Antimicrob Agents Chemother | 10.1128/aac.01724-17 | 2018 | |
| Introducing the NUATEI Consortium: A Mexican Research Program for the Identification of Natural and Synthetic Antimicrobial Compounds for Prevalent Infectious Diseases. | Carrero JC, Espinoza B, Huerta L, Silva-Miranda M, Guzman-Gutierrez SL, Dorazco-Gonzalez A, Reyes-Chilpa R, Espitia C, Sanchez S. | Pharmaceuticals (Basel) | 10.3390/ph17070957 | 2024 | | |
| 3D Imaging of the Transparent Mycobacterium tuberculosis-Infected Lung Verifies the Localization of Innate Immune Cells With Granuloma. | Kang GY, Rhyu HJ, Choi HH, Shin SJ, Hyun YM. | Front Cell Infect Microbiol | 10.3389/fcimb.2020.00226 | 2020 | | |
| LILRB1-HLA-G axis defines a checkpoint driving natural killer cell exhaustion in tuberculosis. | Wang J, Chai Q, Lei Z, Wang Y, He J, Ge P, Lu Z, Qiang L, Zhao D, Yu S, Qiu C, Zhong Y, Li BX, Zhang L, Pang Y, Gao GF, Liu CH. | EMBO Mol Med | 10.1038/s44321-024-00106-1 | 2024 | | |
| Evaluation of Peripheral Blood Parameters of Pulmonary Tuberculosis Patients at St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia: Comparative Study. | Kahase D, Solomon A, Alemayehu M. | J Blood Med | 10.2147/jbm.s237317 | 2020 | | |
| Early detection of Mycobacterium tuberculosis complex in BACTEC MGIT cultures using nucleic acid amplification. | Lin SY, Hwang SC, Yang YC, Wang CF, Chen YH, Chen TC, Lu PL. | Eur J Clin Microbiol Infect Dis | 10.1007/s10096-016-2625-9 | 2016 | | |
| Enzymology | Designing and Construction of a Cloning Vector Encoding mtb32C and mpt51 Fragments of Mycobacterium tuberculosis as a DNA Vaccine Candidate. | Hasanzadeh Haghighi F, Aryan E, Derakhshan M, Gholoobi A, Meshkat Z. | Iran J Pathol | 2018 | | |
| Pathogenicity | Synthesis, molecular docking, antimycobacterial and antimicrobial evaluation of new pyrrolo[3,2-c]pyridine Mannich bases. | Jose G, Suresha Kumara TH, Sowmya HBV, Sriram D, Guru Row TN, Hosamani AA, More SS, Janardhan B, Harish BG, Telkar S, Ravikumar YS. | Eur J Med Chem | 10.1016/j.ejmech.2017.03.015 | 2017 | |
| Antimicrobial Triterpenoids and Ingol Diterpenes from Propolis of Semi-Arid Region of Morocco. | Chimshirova R, Popova M, Chakir A, Valcheva V, Dimitrov S, Trusheva B, Romane A, Bankova V. | Molecules | 10.3390/molecules27072206 | 2022 | | |
| In vitro Antimicrobial Activity Comparison of Linezolid, Tedizolid, Sutezolid and Delpazolid Against Slowly Growing Mycobacteria Isolated in Beijing, China. | Yu X, Huo F, Wang F, Wen S, Jiang G, Xue Y, Dong L, Zhao L, Zhu R, Huang H. | Infect Drug Resist | 10.2147/idr.s332835 | 2021 | | |
| Transcriptome signature of cell viability predicts drug response and drug interaction in Mycobacterium tuberculosis. | Srinivas V, Ruiz RA, Pan M, Immanuel SRC, Peterson EJR, Baliga NS. | Cell Rep Methods | 10.1016/j.crmeth.2021.100123 | 2021 | | |
| Pathogenicity | Repurposing Saquinavir for Host-Directed Therapy to Control Mycobacterium Tuberculosis Infection. | Pires D, Valente S, Calado M, Mandal M, Azevedo-Pereira JM, Anes E. | Front Immunol | 10.3389/fimmu.2021.647728 | 2021 | |
| Synthesis and evaluation of copper(II) complexes with isoniazid-derived hydrazones as anticancer and antitubercular agents. | Firmino GS, de Souza MV, Pessoa C, Lourenco MC, Resende JA, Lessa JA. | Biometals | 10.1007/s10534-016-9968-7 | 2016 | | |
| Phylogeny | Sub-Lineage Specific Phenolic Glycolipid Patterns in the Mycobacterium tuberculosis Complex Lineage 1. | Gisch N, Utpatel C, Gronbach LM, Kohl TA, Schombel U, Malm S, Dobos KM, Hesser DC, Diel R, Gotsch U, Gerdes S, Shuaib YA, Ntinginya NE, Khosa C, Viegas S, Kerubo G, Ali S, Al-Hajoj SA, Ndung'u PW, Rachow A, Hoelscher M, Maurer FP, Schwudke D, Niemann S, Reiling N, Homolka S. | Front Microbiol | 10.3389/fmicb.2022.832054 | 2022 | |
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant Mycobacterium tuberculosis. | Lu X, Hu X, Liu Z, Zhang T, Wang R, Wan B, Franzblau SG, You Q. | Medchemcomm | 10.1039/c7md00146k | 2017 | | |
| A Hydrazine-Hydrazone Adamantine Compound Shows Antimycobacterial Activity and Is a Probable Inhibitor of MmpL3. | Briffotaux J, Xu Y, Huang W, Hui Z, Wang X, Gicquel B, Liu S. | Molecules | 10.3390/molecules27207130 | 2022 | | |
| Pathogenicity | Validating a 14-Drug Microtiter Plate Containing Bedaquiline and Delamanid for Large-Scale Research Susceptibility Testing of Mycobacterium tuberculosis. | Rancoita PMV, Cugnata F, Gibertoni Cruz AL, Borroni E, Hoosdally SJ, Walker TM, Grazian C, Davies TJ, Peto TEA, Crook DW, Fowler PW, Cirillo DM, CRyPTIC Consortiumfor the CRyPTIC Consortiumfor the CRyPTIC Consortium. | Antimicrob Agents Chemother | 10.1128/aac.00344-18 | 2018 | |
| Pathogenicity | Antimycobacterial and Nitric Oxide Production Inhibitory Activities of Triterpenes and Alkaloids from Psychotria nuda (Cham. & Schltdl.) Wawra. | de Carvalho Junior AR, Oliveira Ferreira R, de Souza Passos M, da Silva Boeno SI, Gloria das Virgens LL, Ventura TLB, Calixto SD, Lassounskaia E, de Carvalho MG, Braz-Filho R, Curcino Vieira IJ. | Molecules | 10.3390/molecules24061026 | 2019 | |
| Pathogenicity | TBAJ-876 Displays Bedaquiline-Like Mycobactericidal Potency without Retaining the Parental Drug's Uncoupler Activity. | Sarathy JP, Ragunathan P, Cooper CB, Upton AM, Gruber G, Dick T. | Antimicrob Agents Chemother | 10.1128/aac.01540-19 | 2020 | |
| Non-Thermal Plasma Jet-Treated Medium Induces Selective Cytotoxicity against Mycobacterium tuberculosis-Infected Macrophages. | Lee CB, Lee KI, Kim YJ, Jang IT, Gurmessa SK, Choi EH, Kaushik NK, Kim HJ. | Biomedicines | 10.3390/biomedicines10061243 | 2022 | | |
| Pathogenicity | Combinations of Respiratory Chain Inhibitors Have Enhanced Bactericidal Activity against Mycobacterium tuberculosis. | Berube BJ, Parish T. | Antimicrob Agents Chemother | 10.1128/aac.01677-17 | 2018 | |
| Pathogenicity | Novel 1-(4-substituted benzylidene)-4-(1-(substituted methyl)-2,3-dioxoindolin-5-yl)semicarbazide derivatives for use against Mycobacterium tuberculosis H37Rv (ATCC 27294) and MDR-TB strain. | Raja S, Prakash CR. | Arch Pharm Res | 10.1007/s12272-013-0062-1 | 2013 | |
| Pathogenicity | Novel MenA Inhibitors Are Bactericidal against Mycobacterium tuberculosis and Synergize with Electron Transport Chain Inhibitors. | Berube BJ, Russell D, Castro L, Choi SR, Narayanasamy P, Parish T. | Antimicrob Agents Chemother | 10.1128/aac.02661-18 | 2019 | |
| Pathogenicity | Acquisition of Cross-Resistance to Bedaquiline and Clofazimine following Treatment for Tuberculosis in Pakistan. | Ghodousi A, Rizvi AH, Baloch AQ, Ghafoor A, Khanzada FM, Qadir M, Borroni E, Trovato A, Tahseen S, Cirillo DM. | Antimicrob Agents Chemother | 10.1128/aac.00915-19 | 2019 | |
| Effect of Lagerstroemia tomentosa and Diospyros virginiana methanolic extracts on different drug-resistant strains of Mycobacterium tuberculosis. | Esfahani BN, Hozoorbakhsh F, Rashed Kh, Havaei SA, Heidari K, Moghim Sh. | Res Pharm Sci | 2014 | | ||
| The Funnel: a Screening Technique for Identifying Optimal Two-Drug Combination Chemotherapy Regimens. | Drusano GL, Kim S, Almoslem M, Schmidt S, D'Argenio DZ, Myrick J, Duncanson B, Nole J, Brown D, Peloquin CA, Neely M, Yamada W, Louie A. | Antimicrob Agents Chemother | 10.1128/aac.02172-20 | 2021 | | |
| Antibacterial, Antitubercular and Antiviral Activity Evaluations of Some Arylidenehydrazide Derivatives Bearing Imidazo[2,1-b]thiazole Moiety. | Ulusoy Guzeldemirci N, Karaman B, Kucukbasmaci O. | Turk J Pharm Sci | 10.4274/tjps.25743 | 2017 | | |
| emPAI-assisted strategy enhances screening and assessment of Mycobacterium tuberculosis infection serological markers. | Ma G, Wang P, Yang Y, Wang W, Ma J, Zhou L, Ouyang J, Li R, Zhang S. | Microb Biotechnol | 10.1111/1751-7915.13829 | 2021 | | |
| Metabolism | Mycobacterium tuberculosis Rv2145c Promotes Intracellular Survival by STAT3 and IL-10 Receptor Signaling. | Park HS, Back YW, Jang IT, Lee KI, Son YJ, Choi HG, Dang TB, Kim HJ. | Front Immunol | 10.3389/fimmu.2021.666293 | 2021 | |
| Comparison Of drrA And drrB Efflux Pump Genes Expression In Drug-Susceptible And -Resistant Mycobacterium tuberculosis Strains Isolated From Tuberculosis Patients In Iran. | Khosravi AD, Sirous M, Absalan Z, Tabandeh MR, Savari M. | Infect Drug Resist | 10.2147/idr.s221823 | 2019 | | |
| Pathogenicity | Synthesis and anti-mycobacterial activity of 2-chloronicotinaldehydes based novel 1H-1,2,3-triazolylbenzohydrazides. | Suman P, Dayakar C, Rajkumar K, Yashwanth B, Yogeeswari P, Sriram D, Rao JV, Raju BC. | Bioorg Med Chem Lett | 10.1016/j.bmcl.2015.04.009 | 2015 | |
| Wild mouse gut microbiota limits initial tuberculosis infection in BALB/c mice. | Xie M, Tsai CY, McAdams ZL, Oo M, Hansen M, Dougher M, Sansano A, Watson A, LoMauro K, Antilus-Sainte R, Ericsson A, Dartois V, Gengenbacher M. | PLoS One | 10.1371/journal.pone.0288290 | 2023 | | |
| Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection. | Bohrer AC, Castro E, Tocheny CE, Assmann M, Schwarz B, Bohrnsen E, Makiya MA, Legrand F, Hilligan KL, Baker PJ, Torres-Juarez F, Hu Z, Ma H, Wang L, Niu L, Wen Z, Lee SH, Kamenyeva O, Tuberculosis Imaging Program, Kauffman KD, Donato M, Sher A, Barber DL, Via LE, Scriba TJ, Khatri P, Song Y, Wong KW, Bosio CM, Klion AD, Mayer-Barber KD. | Cell Rep | 10.1016/j.celrep.2022.111144 | 2022 | | |
| Enzymology | Plasma Levels of Rifampin Correlate with the Tuberculosis Drug Activity Assay. | Niward K, Ek Blom L, Davies Forsman L, Bruchfeld J, Eliasson E, Schon T, Chryssanthou E, Paues J. | Antimicrob Agents Chemother | 10.1128/aac.00218-18 | 2018 | |
| Genetics | Whole-Genome Sequencing for Resistance Level Prediction in Multidrug-Resistant Tuberculosis. | Li J, Yang T, Hong C, Yang Z, Wu L, Gao Q, Yang H, Tan W. | Microbiol Spectr | 10.1128/spectrum.02714-21 | 2022 | |
| Pathogenicity | Super-Resolution Microscopy Reveals a Direct Interaction of Intracellular Mycobacterium tuberculosis with the Antimicrobial Peptide LL-37. | Deshpande D, Grieshober M, Wondany F, Gerbl F, Noschka R, Michaelis J, Stenger S. | Int J Mol Sci | 10.3390/ijms21186741 | 2020 | |
| Pathogenicity | Linezolid Kills Acid-Phase and Nonreplicative-Persister-Phase Mycobacterium tuberculosis in a Hollow-Fiber Infection Model. | Drusano GL, Myrick J, Maynard M, Nole J, Duncanson B, Brown D, Schmidt S, Neely M, Scanga CA, Peloquin C, Louie A. | Antimicrob Agents Chemother | 10.1128/aac.00221-18 | 2018 | |
| Characterization of Streptomyces sp. LS462 with high productivity of echinomycin, a potent antituberculosis and synergistic antifungal antibiotic. | Chen C, Chen X, Ren B, Guo H, Abdel-Mageed WM, Liu X, Song F, Zhang L. | J Ind Microbiol Biotechnol | 10.1093/jimb/kuab079 | 2021 | | |
| Phylogeny | Flavonoids from Clerodendrum genus and their biological activities. | Mamuaja MN, Herlina T, Rumampuk RJ, Maksum IP, Rukayadi Y. | ADMET DMPK | 10.5599/admet.2442 | 2024 | |
| Novel copper(II) complexes with hydrazides and heterocyclic bases: Synthesis, structure and biological studies. | Paixao DA, Marzano IM, Jaimes EHL, Pivatto M, Campos DL, Pavan FR, Deflon VM, Maia PIDS, Da Costa Ferreira AM, Uehara IA, Silva MJB, Botelho FV, Pereira-Maia EC, Guilardi S, Guerra W. | J Inorg Biochem | 10.1016/j.jinorgbio.2017.04.024 | 2017 | | |
| Pathogenicity | In vitro activity of isoimperatorin, alone and in combination, against Mycobacterium tuberculosis. | Guo N, Wu J, Fan J, Yuan P, Shi Q, Jin K, Cheng W, Zhao X, Zhang Y, Li W, Tang X, Yu L. | Lett Appl Microbiol | 10.1111/lam.12195 | 2014 | |
| Pathogenicity | Reinvestigation of the structure-activity relationships of isoniazid. | Hegde P, Boshoff HIM, Rusman Y, Aragaw WW, Salomon CE, Dick T, Aldrich CC. | Tuberculosis (Edinb) | 10.1016/j.tube.2021.102100 | 2021 | |
| Isolation of anti-mycobacterial compounds from Curtisia dentata (Burm.f.) C.A.Sm (Curtisiaceae). | Fadipe VO, Mongalo NI, Opoku AR, Dikhoba PM, Makhafola TJ. | BMC Complement Altern Med | 10.1186/s12906-017-1818-9 | 2017 | | |
| Pathogenicity | Novel Assay Platform to Evaluate Intracellular Killing of Mycobacterium tuberculosis: In Vitro and In Vivo Validation. | Horvati K, Fodor K, Palyi B, Henczko J, Balka G, Gyulai G, Kiss E, Biri-Kovacs B, Senoner Z, Bosze S. | Front Immunol | 10.3389/fimmu.2021.750496 | 2021 | |
| Characterization of pncA Mutations and Prediction of PZA Resistance in Mycobacterium tuberculosis Clinical Isolates From Chongqing, China. | Li K, Yang Z, Gu J, Luo M, Deng J, Chen Y. | Front Microbiol | 10.3389/fmicb.2020.594171 | 2020 | | |
| Single-nucleotide polymorphisms and activities of indoleamine 2,3-dioxygenase isoforms, IDO1 and IDO2, in tuberculosis patients. | Cao T, Dai G, Chu H, Kong C, Duan H, Tian N, Sun Z. | Hereditas | 10.1186/s41065-022-00219-y | 2022 | | |
| Minocycline intra-bacterial pharmacokinetic hysteresis as a basis for pharmacologic memory and a backbone for once-a-week pan-tuberculosis therapy. | Deshpande D, Srivastava S, Pasipanodya JG, Gumbo T. | Front Pharmacol | 10.3389/fphar.2022.1024608 | 2022 | | |
| Metabolism | Human Macrophages Exhibit GM-CSF Dependent Restriction of Mycobacterium tuberculosis Infection via Regulating Their Self-Survival, Differentiation and Metabolism. | Mishra A, Singh VK, Jagannath C, Subbian S, Restrepo BI, Gauduin MC, Khan A. | Front Immunol | 10.3389/fimmu.2022.859116 | 2022 | |
| Whole-genome sequence analysis and comparisons between drug-resistance mutations and minimum inhibitory concentrations of Mycobacterium tuberculosis isolates causing M/XDR-TB. | Nonghanphithak D, Kaewprasert O, Chaiyachat P, Reechaipichitkul W, Chaiprasert A, Faksri K. | PLoS One | 10.1371/journal.pone.0244829 | 2020 | | |
| A mycobacterial effector promotes ferroptosis-dependent pathogenicity and dissemination. | Qiang L, Zhang Y, Lei Z, Lu Z, Tan S, Ge P, Chai Q, Zhao M, Zhang X, Li B, Pang Y, Zhang L, Liu CH, Wang J. | Nat Commun | 10.1038/s41467-023-37148-x | 2023 | | |
| Structure Characterization and Biological Activity of 2-Arylbenzofurans from an Indonesian Plant, Sesbania grandiflora (L.) Pers. | Noviany N, Samadi A, Yuliyan N, Hadi S, Aziz M, Purwitasari N, Mohamad S, Ismail NN, Gable KP, Mahmud T. | Phytochem Lett | 10.1016/j.phytol.2019.12.008 | 2020 | | |
| Rapid Detection of Streptomycin-Resistant Mycobacterium tuberculosis by rpsL-Restriction Fragment Length Polymorphism. | Karimi S, Mirhendi H, Zaniani FR, Manesh SE, Salehi M, Esfahani BN. | Adv Biomed Res | 10.4103/abr.abr_240_16 | 2017 | | |
| Discovery of a Natural Product That Binds to the Mycobacterium tuberculosis Protein Rv1466 Using Native Mass Spectrometry. | Elnaas AR, Grice D, Han J, Feng Y, Capua AD, Mak T, Laureanti JA, Buchko GW, Myler PJ, Cook G, Quinn RJ, Liu M. | Molecules | 10.3390/molecules25102384 | 2020 | | |
| Optimized APEX2 peroxidase-mediated proximity labeling in fast- and slow-growing mycobacteria. | Ahamed M, Jaisinghani N, Li M, Winkeler I, Silva S, Previti ML, Seeliger JC. | Methods Enzymol | 10.1016/bs.mie.2021.11.021 | 2022 | | |
| Metabolism | In vivo virulence of Mycobacterium tuberculosis depends on a single homologue of the LytR-CpsA-Psr proteins. | Malm S, Maass S, Schaible UE, Ehlers S, Niemann S. | Sci Rep | 10.1038/s41598-018-22012-6 | 2018 | |
| Elucidating the Antimycobacterial Mechanism of Action of Decoquinate Derivative RMB041 Using Metabolomics. | Knoll KE, Lindeque Z, Adeniji AA, Oosthuizen CB, Lall N, Loots DT. | Antibiotics (Basel) | 10.3390/antibiotics10060693 | 2021 | | |
| Phylogeny | Clonality and genetic profiles of drug-resistant Mycobacterium tuberculosis in the Eastern Cape Province, South Africa. | Bhembe NL, Nwodo UU, Okoh AI, Obi CL, Mabinya LV, Green E. | Microbiologyopen | 10.1002/mbo3.449 | 2019 | |
| Building Optimal Three-Drug Combination Chemotherapy Regimens. | Drusano GL, Neely MN, Kim S, Yamada WM, Schmidt S, Duncanson B, Nole J, Mtchedlidze N, Peloquin CA, Louie A. | Antimicrob Agents Chemother | 10.1128/aac.01610-20 | 2020 | | |
| Pathogenicity | Mutations of folC cause increased susceptibility to sulfamethoxazole in Mycobacterium tuberculosis. | Wang R, Li K, Yu J, Deng J, Chen Y. | Sci Rep | 10.1038/s41598-020-80213-4 | 2021 | |
| Unbiased Identification of Angiogenin as an Endogenous Antimicrobial Protein With Activity Against Virulent Mycobacterium tuberculosis. | Noschka R, Gerbl F, Loffler F, Kubis J, Rodriguez AA, Mayer D, Grieshober M, Holch A, Raasholm M, Forssmann WG, Spellerberg B, Wiese S, Weidinger G, Standker L, Stenger S. | Front Microbiol | 10.3389/fmicb.2020.618278 | 2020 | | |
| Pathogenicity | Synthesis and Antimycobacterial Activity of 3-Phenyl-1H-indoles. | Jardim Etchart R, Rambo RS, Lopes Abbadi B, Sperotto N, Ev Neves C, Fries Silva F, Dornelles M, Duarte L, Souza Macchi F, Alberton Perello M, Vescia Lourega R, Valim Bizarro C, Basso LA, Machado P. | Molecules | 10.3390/molecules26175148 | 2021 | |
| Metabolism | Human mesenchymal stem cell based intracellular dormancy model of Mycobacterium tuberculosis. | Singh VK, Mishra A, Bark S, Mani A, Subbian S, Hunter RL, Jagannath C, Khan A. | Microbes Infect | 10.1016/j.micinf.2020.05.015 | 2020 | |
| Synthesis, biological evaluation and molecular docking studies of 6-(4-nitrophenoxy)-1H-imidazo[4,5-b]pyridine derivatives as novel antitubercular agents: future DprE1 inhibitors. | Gawad J, Bonde C. | Chem Cent J | 10.1186/s13065-018-0515-1 | 2018 | | |
| Safety and pharmacokinetics-pharmacodynamics of a shorter tuberculosis treatment with high-dose pyrazinamide and rifampicin: a study protocol of a phase II clinical trial (HighShort-RP). | Ekqvist D, Bornefall A, Augustinsson D, Sonnerbrandt M, Nordvall MJ, Fredrikson M, Carlsson B, Sandstedt M, Simonsson USH, Alffenaar JC, Paues J, Niward K. | BMJ Open | 10.1136/bmjopen-2021-054788 | 2022 | | |
| Antitubercular Activity of the Fungus Gliocladium sp. MR41 Strain. | Uc-Cachon AH, Gamboa-Angulo M, Borges-Argaez R, Reyes-Estebanez M, Said-Fernandez S, Molina-Salinas GM. | Iran J Pharm Res | 10.22037/ijpr.2019.1100667 | 2019 | | |
| Pathogenicity | In Vitro Activity of Copper(II) Complexes, Loaded or Unloaded into a Nanostructured Lipid System, against Mycobacterium tuberculosis. | Silva PB, Souza PC, Calixto GM, Lopes Ede O, Frem RC, Netto AV, Mauro AE, Pavan FR, Chorilli M. | Int J Mol Sci | 10.3390/ijms17050745 | 2016 | |
| Doubly end-on azido bridged mixed-valence cobalt trinuclear complex: Spectral study, VTM, inhibitory effect and antimycobacterial activity on human carcinoma and tuberculosis cells. | Datta A, Das K, Sen C, Karan NK, Huang JH, Lin CH, Garribba E, Sinha C, Askun T, Celikboyun P, Mane SB. | Spectrochim Acta A Mol Biomol Spectrosc | 10.1016/j.saa.2015.04.014 | 2015 | | |
| A Leucyl-tRNA Synthetase Inhibitor with Broad-Spectrum Anti-Mycobacterial Activity. | Ganapathy US, Del Rio RG, Cacho-Izquierdo M, Ortega F, Lelievre J, Barros-Aguirre D, Lindman M, Dartois V, Gengenbacher M, Dick T. | Antimicrob Agents Chemother | 10.1128/aac.02420-20 | 2023 | | |
| Genetics | Whole Genome Sequencing Results Associated with Minimum Inhibitory Concentrations of 14 Anti-Tuberculosis Drugs among Rifampicin-Resistant Isolates of Mycobacterium Tuberculosis from Iran. | Kardan-Yamchi J, Kazemian H, Battaglia S, Abtahi H, Foroushani AR, Hamzelou G, Cirillo DM, Ghodousi A, Feizabadi MM. | J Clin Med | 10.3390/jcm9020465 | 2020 | |
| Direct Resazurin Microplate Assay in Drug Susceptibility Testing of Smear-Positive Sputum Samples against Mycobacterium tuberculosis. | Jamil NIN, Wahab WNAWA, Ali IA, Yahaya ML. | Malays J Med Sci | 10.21315/mjms2018.25.6.6 | 2018 | | |
| Genetics | Genetic and Virulence Characteristics of Linezolid and Pretomanid Dual Drug-Resistant Strains Induced from Mycobacterium tuberculosis in vitro. | Hu M, Fu L, Wang B, Xu J, Guo S, Zhao J, Li Y, Chen X, Lu Y. | Infect Drug Resist | 10.2147/idr.s257145 | 2020 | |
| Pathogenicity | Bioactivity of pyridine-2-thiolato-1-oxide metal complexes: Bi(III), Fe(III) and Ga(III) complexes as potent anti-Mycobacterium tuberculosis prospective agents. | Machado I, Marino LB, Demoro B, Echeverria GA, Piro OE, Leite CQ, Pavan FR, Gambino D. | Eur J Med Chem | 10.1016/j.ejmech.2014.09.067 | 2014 | |
| Inhibition of DXR in the MEP pathway with lipophilic N-alkoxyaryl FR900098 analogs. | Bague D, Wang R, Hodge D, Mikati MO, Roma JS, Boshoff HI, Dailey AL, Girma M, Couch RD, Odom John AR, Dowd CS. | RSC Med Chem | 10.1039/d3md00642e | 2024 | | |
| Tuberculostearic Acid-Containing Phosphatidylinositols as Markers of Bacterial Burden in Tuberculosis. | Brandenburg J, Heyckendorf J, Marwitz F, Zehethofer N, Linnemann L, Gisch N, Karakose H, Reimann M, Kranzer K, Kalsdorf B, Sanchez-Carballo P, Weinkauf M, Scholz V, Malm S, Homolka S, Gaede KI, Herzmann C, Schaible UE, Holscher C, Reiling N, Schwudke D. | ACS Infect Dis | 10.1021/acsinfecdis.2c00075 | 2022 | | |
| Lactococcus lactis FNBPA+ (pValac:e6ag85a) Induces Cellular and Humoral Immune Responses After Oral Immunization of Mice. | de Castro CP, Souza BM, Mancha-Agresti P, Pereira VB, Zurita-Turk M, Preisser TM, da Cunha VP, Dos Santos JSC, Leclercq SY, Azevedo V, Miyoshi A. | Front Microbiol | 10.3389/fmicb.2021.676172 | 2021 | | |
| Gran1: A Granulysin-Derived Peptide with Potent Activity against Intracellular Mycobacterium tuberculosis. | Noschka R, Wondany F, Kizilsavas G, Weil T, Weidinger G, Walther P, Michaelis J, Stenger S. | Int J Mol Sci | 10.3390/ijms22168392 | 2021 | | |
| Detection of Resistance to Fluoroquinolones and Second-Line Injectable Drugs Among Mycobacterium tuberculosis by a Reverse Dot Blot Hybridization Assay. | Li G, Guo Q, Liu H, Wan L, Jiang Y, Li M, Zhao LL, Zhao X, Liu Z, Wan K. | Infect Drug Resist | 10.2147/idr.s270209 | 2020 | | |
| Fluoroquinolones' Biological Activities against Laboratory Microbes and Cancer Cell Lines. | Suaifan GARY, Mohammed AAM, Alkhawaja BA. | Molecules | 10.3390/molecules27051658 | 2022 | | |
| Pathogenicity | Intra- and extracellular activities of trimethoprim-sulfamethoxazole against susceptible and multidrug-resistant Mycobacterium tuberculosis. | Davies Forsman L, Schon T, Simonsson US, Bruchfeld J, Larsson M, Jureen P, Sturegard E, Giske CG, Angeby K. | Antimicrob Agents Chemother | 10.1128/aac.02995-14 | 2014 | |
| Pathogenicity | Clofazimine Exposure In Vitro Selects Efflux Pump Mutants and Bedaquiline Resistance. | Ismail N, Peters RPH, Ismail NA, Omar SV. | Antimicrob Agents Chemother | 10.1128/aac.02141-18 | 2019 | |
| In vitro anti-tuberculosis effect of probiotic Lacticaseibacillus rhamnosus PMC203 isolated from vaginal microbiota. | Rahim MA, Seo H, Kim S, Tajdozian H, Barman I, Lee Y, Lee S, Song HY. | Sci Rep | 10.1038/s41598-022-12413-z | 2022 | | |
| Pathogenicity | Activity of Moxifloxacin against Mycobacterium tuberculosis in Acid Phase and Nonreplicative-Persister Phenotype Phase in a Hollow-Fiber Infection Model. | Louie A, Duncanson B, Myrick J, Maynard M, Nole J, Brown D, Schmidt S, Neely M, Scanga CA, Peloquin C, Drusano GL. | Antimicrob Agents Chemother | 10.1128/aac.01470-18 | 2018 | |
| Performance of Tuberculosis Molecular Bacterial Load Assay Compared to Alere TB-LAM in Urine of Pulmonary Tuberculosis Patients with HIV Co-Infections. | Mapamba DA, Sauli E, Lalashowi J, Buza J, John J, Mwaisango Z, Tarmo P, Sabi I, Rachow A, Ntinginya NE, Mtafya B. | Int J Mol Sci | 10.3390/ijms24043715 | 2023 | | |
| Performance of MTBDRplus assay in detecting multidrug resistant tuberculosis at hospital level. | Kebede A, Demisse D, Assefa M, Getachew Z, Yenew B, Tedla Y, Ameni G. | BMC Res Notes | 10.1186/s13104-017-2989-7 | 2017 | | |
| Pathogenicity | Using Mycobacterium tuberculosis Single-Nucleotide Polymorphisms To Predict Fluoroquinolone Treatment Response. | Seifert M, Capparelli E, Catanzaro DG, Rodwell TC. | Antimicrob Agents Chemother | 10.1128/aac.00076-19 | 2019 | |
| Genetics | Genotypic Distribution and a Potential Diagnostic Assay of Multidrug-Resistant Tuberculosis in Northern Thailand. | Anukool U, Phunpae P, Tharinjaroen CS, Butr-Indr B, Saikaew S, Netirat N, Intorasoot S, Suthachai V, Tragoolpua K, Chaiprasert A. | Infect Drug Resist | 10.2147/idr.s263082 | 2020 | |
| Genetics | Rifampicin-Monoresistant Tuberculosis Is Not the Same as Multidrug-Resistant Tuberculosis: a Descriptive Study from Khayelitsha, South Africa. | Salaam-Dreyer Z, Streicher EM, Sirgel FA, Menardo F, Borrell S, Reinhard M, Doetsch A, Cudahy PGT, Mohr-Holland E, Daniels J, Dippenaar A, Nicol MP, Gagneux S, Warren RM, Cox H. | Antimicrob Agents Chemother | 10.1128/aac.00364-21 | 2021 | |
| Measuring of Mycobacterium tuberculosis growth. A correlation of the optical measurements with colony forming units. | Penuelas-Urquides K, Villarreal-Trevino L, Silva-Ramirez B, Rivadeneyra-Espinoza L, Said-Fernandez S, de Leon MB. | Braz J Microbiol | 10.1590/s1517-83822013000100042 | 2013 | | |
| Genetics | In Vivo-Selected Pyrazinoic Acid-Resistant Mycobacterium tuberculosis Strains Harbor Missense Mutations in the Aspartate Decarboxylase PanD and the Unfoldase ClpC1. | Gopal P, Tasneen R, Yee M, Lanoix JP, Sarathy J, Rasic G, Li L, Dartois V, Nuermberger E, Dick T. | ACS Infect Dis | 10.1021/acsinfecdis.7b00017 | 2017 | |
| Novel Role for Macrophage Galactose-Type Lectin-1 to Regulate Innate Immunity against Mycobacterium tuberculosis. | Naqvi KF, Huante MB, Saito TB, Endsley MA, Gelman BB, Endsley JJ. | J Immunol | 10.4049/jimmunol.2001276 | 2021 | | |
| EST12 regulates Myc expression and enhances anti-mycobacterial inflammatory response via RACK1-JNK-AP1-Myc immune pathway. | Wu J, Luo FL, Xie Y, Xiong H, Gao Y, Liu G, Zhang XL. | Front Immunol | 10.3389/fimmu.2022.943174 | 2022 | | |
| Antimicrobial Activity of Quinoline-Based Hydroxyimidazolium Hybrids. | Insuasty D, Vidal O, Bernal A, Marquez E, Guzman J, Insuasty B, Quiroga J, Svetaz L, Zacchino S, Puerto G, Abonia R. | Antibiotics (Basel) | 10.3390/antibiotics8040239 | 2019 | | |
| A Phenotarget Approach for Identifying an Alkaloid Interacting with the Tuberculosis Protein Rv1466. | Xie Y, Feng Y, Di Capua A, Mak T, Buchko GW, Myler PJ, Liu M, Quinn RJ. | Mar Drugs | 10.3390/md18030149 | 2020 | | |
| MiR-25 blunts autophagy and promotes the survival of Mycobacterium tuberculosis by regulating NPC1. | Dong W, Wang G, Feng J, Li P, Wang R, Lu H, Lu W, Wang C, Wang X, Chen H, Xiang Y, Tan C. | iScience | 10.1016/j.isci.2022.104279 | 2022 | | |
| The Anti-Mycobacterial Activity Of Ag, ZnO, And Ag- ZnO Nanoparticles Against MDR- And XDR-Mycobacterium tuberculosis. | Heidary M, Zaker Bostanabad S, Amini SM, Jafari A, Ghalami Nobar M, Ghodousi A, Kamalzadeh M, Darban-Sarokhalil D. | Infect Drug Resist | 10.2147/idr.s221408 | 2019 | | |
| Carbonyl Cyanide 3-Chlorophenylhydrazone (CCCP) Exhibits Direct Antibacterial Activity Against Mycobacterium abscessus. | Chen S, Teng T, Zhang Z, Shang Y, Xiao H, Jiang G, Wang F, Jia J, Dong L, Zhao L, Chu N, Huang H. | Infect Drug Resist | 10.2147/idr.s303113 | 2021 | | |
| A Dendritic Cell-Activating Rv1876 Protein Elicits Mycobacterium Bovis BCG-Prime Effect via Th1-Immune Response. | Choi S, Choi HG, Back YW, Park HS, Lee KI, Gurmessa SK, Pham TA, Kim HJ. | Biomolecules | 10.3390/biom11091306 | 2021 | | |
| OPC-167832, a Novel Carbostyril Derivative with Potent Antituberculosis Activity as a DprE1 Inhibitor. | Hariguchi N, Chen X, Hayashi Y, Kawano Y, Fujiwara M, Matsuba M, Shimizu H, Ohba Y, Nakamura I, Kitamoto R, Shinohara T, Uematsu Y, Ishikawa S, Itotani M, Haraguchi Y, Takemura I, Matsumoto M. | Antimicrob Agents Chemother | 10.1128/aac.02020-19 | 2020 | | |
| Molecular characterization of genetic mutations with fitness loss in pulmonary tuberculosis patients associated with HIV co-infection in Northwest Amhara, Ethiopia. | Seid A, Kassa M, Girma Y, Dereb E, Nureddin S, Abebe A, Berhane N. | SAGE Open Med | 10.1177/20503121231208266 | 2023 | | |
| Pathogenicity | A rapid culture system uninfluenced by an inoculum effect increases reliability and convenience for drug susceptibility testing of Mycobacterium tuberculosis. | Jung YG, Kim H, Lee S, Kim S, Jo E, Kim EG, Choi J, Kim HJ, Yoo J, Lee HJ, Kim H, Jung H, Ryoo S, Kwon S. | Sci Rep | 10.1038/s41598-018-26419-z | 2018 | |
| Pathogenicity | Synthesis, antimycobacterial and antibacterial activity of fluoroquinolone derivatives containing an 3-alkoxyimino-4-(cyclopropylanimo)methylpyrrolidine moiety. | Zhang T, Shen W, Liu M, Zhang R, Wang M, Li L, Wang B, Guo H, Lu Y. | Eur J Med Chem | 10.1016/j.ejmech.2015.09.030 | 2015 | |
| Pathogenicity | Fast detection of drug interaction in Mycobacterium tuberculosis by a checkerboard resazurin method. | Caleffi-Ferracioli KR, Maltempe FG, Siqueira VL, Cardoso RF. | Tuberculosis (Edinb) | 10.1016/j.tube.2013.09.001 | 2013 | |
| Pathogenicity | Value of pyrazinamide for composition of new treatment regimens for multidrug-resistant Mycobacterium tuberculosis in China. | Xia H, van den Hof S, Cobelens F, Zhou Y, Zhao B, Wang S, Zhao Y. | BMC Infect Dis | 10.1186/s12879-020-4758-9 | 2020 | |
| Pathogenicity | Antimycobacterial activity of Citrullus colocynthis (L.) Schrad. against drug sensitive and drug resistant Mycobacterium tuberculosis and MOTT clinical isolates. | Mehta A, Srivastva G, Kachhwaha S, Sharma M, Kothari SL. | J Ethnopharmacol | 10.1016/j.jep.2013.06.022 | 2013 | |
| Pathogenicity | A novel derivative of the fungal antimicrobial peptide plectasin is active against Mycobacterium tuberculosis. | Tenland E, Krishnan N, Ronnholm A, Kalsum S, Puthia M, Morgelin M, Davoudi M, Otrocka M, Alaridah N, Glegola-Madejska I, Sturegard E, Schmidtchen A, Lerm M, Robertson BD, Godaly G. | Tuberculosis (Edinb) | 10.1016/j.tube.2018.10.008 | 2018 | |
| Pathogenicity | Genotype analysis of ofloxacin-resistant multidrug-resistant Mycobacterium tuberculosis isolates in a multicentered study from India. | Gupta A, Sinha P, Rathod S, Shanmugam SK, Uma Devi KR, Anupurba S, Nema V. | Indian J Med Res | 10.4103/ijmr.ijmr_493_18 | 2020 | |
| Novel Antiviral and Antibacterial Activities of Hibiscus schizopetalus. | El-Shiekh RA, Abdelmohsen UR, Ashour HM, Ashour RM. | Antibiotics (Basel) | 10.3390/antibiotics9110756 | 2020 | | |
| Pathogenicity | Evaluation of the Efficiency of the Sample Inactivation Reagent in the Abbott RealTime MTB Assay for Inactivation of Mycobacterium tuberculosis. | Qi C, Wallis C, Pahalawatta V, Frank A, Ramdin N, Viana R, Abravaya K, Leckie G, Tang N. | J Clin Microbiol | 10.1128/jcm.00598-15 | 2015 | |
| Pulmonary tuberculosis caused by Mycobacterium bovis in China. | Jiang G, Wang G, Chen S, Yu X, Wang X, Zhao L, Ma Y, Dong L, Huang H. | Sci Rep | 10.1038/srep08538 | 2015 | | |
| Efficacy of integrating short-course chemotherapy with Chinese herbs to treat multi-drug resistant pulmonary tuberculosis in China: a study protocol. | Zhang SX, Qiu L, Li C, Zhou W, Tian LM, Zhang HY, Ma ZF, Wu XW, Huang X, Jiang YW, Zhang SY, Lu ZH. | Infect Dis Poverty | 10.1186/s40249-021-00913-5 | 2021 | | |
| Pathogenicity | Desertomycin G, a New Antibiotic with Activity against Mycobacterium tuberculosis and Human Breast Tumor Cell Lines Produced by Streptomyces althioticus MSM3, Isolated from the Cantabrian Sea Intertidal Macroalgae Ulva sp. | Brana AF, Sarmiento-Vizcaino A, Perez-Victoria I, Martin J, Otero L, Palacios-Gutierrez JJ, Fernandez J, Mohamedi Y, Fontanil T, Salmon M, Cal S, Reyes F, Garcia LA, Blanco G. | Mar Drugs | 10.3390/md17020114 | 2019 | |
| The Relation Between the Emergence of Fluoroquinolone Resistance and Fluoroquinolone Exposure in New Cases of Active Pulmonary Tuberculosis. | Aydin Kayali R, Ozkan SA, Bicmen C, Erer OF. | Turk Thorac J | 10.5152/turkthoracj.2021.19128 | 2021 | | |
| Pathogenicity | Synthesis and antimycobacterial activity of isoniazid derivatives from renewable fatty acids. | Rodrigues MO, Cantos JB, D'Oca CR, Soares KL, Coelho TS, Piovesan LA, Russowsky D, da Silva PA, D'Oca MG. | Bioorg Med Chem | 10.1016/j.bmc.2013.09.034 | 2013 | |
| Mycobacterium tuberculosis Rv3628 isan effective adjuvant via activationof dendritic cells for cancer immunotherapy. | Wu J, Yang H, Xu JC, Hu Z, Gu WF, Chen ZY, Xia JX, Lowrie DB, Lu SH, Fan XY. | Mol Ther Oncolytics | 10.1016/j.omto.2021.10.003 | 2021 | | |
| Pathogenicity | ODELAM, rapid sequence-independent detection of drug resistance in isolates of Mycobacterium tuberculosis. | Herricks T, Donczew M, Mast FD, Rustad T, Morrison R, Sterling TR, Sherman DR, Aitchison JD. | Elife | 10.7554/elife.56613 | 2020 | |
| Pathogenicity | Novel 1,2,3-triazole derivatives for use against Mycobacterium tuberculosis H37Rv (ATCC 27294) strain. | Boechat N, Ferreira VF, Ferreira SB, de Lourdes G Ferreira M, de C da Silva F, Bastos MM, Dos S Costa M, Lourenco MC, Pinto AC, Krettli AU, Aguiar AC, Teixeira BM, da Silva NV, Martins PR, Bezerra FA, Camilo AL, da Silva GP, Costa CC. | J Med Chem | 10.1021/jm2003624 | 2011 | |
| The ethanolic extract of ashitaba stem (Angelica keskei [Miq.] Koidz) as future antituberculosis. | Kusuma SAF, Iskandar Y, Dewanti MA. | J Adv Pharm Technol Res | 10.4103/japtr.japtr_283_17 | 2018 | | |
| Interaction of Mycobacteria With Host Cell Inflammasomes. | Rastogi S, Briken V. | Front Immunol | 10.3389/fimmu.2022.791136 | 2022 | | |
| Mycobacterium tuberculosis clinical isolates of the Beijing and East-African Indian lineage induce fundamentally different host responses in mice compared to H37Rv. | Mourik BC, de Steenwinkel JEM, de Knegt GJ, Huizinga R, Verbon A, Ottenhoff THM, van Soolingen D, Leenen PJM. | Sci Rep | 10.1038/s41598-019-56300-6 | 2019 | | |
| A global proficiency testing programme for Xpert® MTB/RIF using dried tube specimens, 2013-2015. | Klein K, DeGruy K, Rey Z, Hall P, Kim A, Gutreuter S, Alexander H. | Afr J Lab Med | 10.4102/ajlm.v9i1.1167 | 2020 | | |
| Antimicrobial Action Mechanisms of Natural Compounds Isolated from Endophytic Microorganisms. | Eshboev F, Mamadalieva N, Nazarov PA, Hussain H, Katanaev V, Egamberdieva D, Azimova S. | Antibiotics (Basel) | 10.3390/antibiotics13030271 | 2024 | | |
| Pathogenicity | In Vitro Susceptibility Testing of GSK656 against Mycobacterium Species. | Dong W, Li S, Wen S, Jing W, Shi J, Ma Y, Huo F, Gao F, Pang Y, Lu J. | Antimicrob Agents Chemother | 10.1128/aac.01577-19 | 2020 | |
| Pathogenicity | Repurposing ethyl bromopyruvate as a broad-spectrum antibacterial. | Kumar A, Boradia VM, Thakare R, Singh AK, Gani Z, Das S, Patidar A, Dasgupta A, Chopra S, Raje M, Raje CI. | J Antimicrob Chemother | 10.1093/jac/dky555 | 2019 | |
| Unveiling the Pharmacological Significance of Marine Streptomyces violaceusniger KS20: Isolation, Characterization, and Assessment of Its Biomedical Applications. | Chakraborty B, Shashiraj KN, Kumar RS, Bhat MP, Basavarajappa DS, Almansour AI, Perumal K, Nayaka S. | Metabolites | 10.3390/metabo13091022 | 2023 | | |
| Clinical Validation of the QMAC-DST System for Testing the Drug Susceptibility of Mycobacterium tuberculosis to First- and Second-Line Drugs. | Lee S, Chu D, Choi YM, Jo E, Kim S, Kim H, Kim HJ, Chang J, Sung H, Kang G, Jin B, Kim EG, Kwon S, Kim MN. | Front Microbiol | 10.3389/fmicb.2019.00706 | 2019 | | |
| Pathogenicity | Delamanid, Bedaquiline, and Linezolid Minimum Inhibitory Concentration Distributions and Resistance-related Gene Mutations in Multidrug-resistant and Extensively Drug-resistant Tuberculosis in Korea. | Yang JS, Kim KJ, Choi H, Lee SH. | Ann Lab Med | 10.3343/alm.2018.38.6.563 | 2018 | |
| Model-Based Meta-Analysis of Relapsing Mouse Model Studies from the Critical Path to Tuberculosis Drug Regimens Initiative Database. | Berg A, Clary J, Hanna D, Nuermberger E, Lenaerts A, Ammerman N, Ramey M, Hartley D, Hermann D. | Antimicrob Agents Chemother | 10.1128/aac.01793-21 | 2022 | | |
| Pathogenicity | MenT nucleotidyltransferase toxins extend tRNA acceptor stems and can be inhibited by asymmetrical antitoxin binding. | Xu X, Usher B, Gutierrez C, Barriot R, Arrowsmith TJ, Han X, Redder P, Neyrolles O, Blower TR, Genevaux P. | Nat Commun | 10.1038/s41467-023-40264-3 | 2023 | |
| Intracellular and in vivo activities of oxazolidinone drugs against Mycobacterium avium complex infection. | Lee JM, Kim LH, Kim SY, Jhun BW, Lee W, Shin SJ. | Sci Rep | 10.1038/s41598-023-48001-y | 2023 | | |
| Fundamental Cell Morphologies Examined With Cryo-TEM of the Species in the Novel Five Genera Robustly Correlate With New Classification in Family Mycobacteriaceae. | Yamada H, Chikamatsu K, Aono A, Murata K, Miyazaki N, Kayama Y, Bhatt A, Fujiwara N, Maeda S, Mitarai S. | Front Microbiol | 10.3389/fmicb.2020.562395 | 2020 | | |
| Pathogenicity | Functionalized Dioxonaphthoimidazoliums: A Redox Cycling Chemotype with Potent Bactericidal Activities against Mycobacterium tuberculosis. | Fridianto KT, Li M, Hards K, Negatu DA, Cook GM, Dick T, Lam Y, Go ML. | J Med Chem | 10.1021/acs.jmedchem.1c01383 | 2021 | |
| Mycobacterium tuberculosis Rv3463 induces mycobactericidal activity in macrophages by enhancing phagolysosomal fusion and exhibits therapeutic potential. | Park HS, Back YW, Shin KW, Bae HS, Lee KI, Choi HG, Choi S, Lee HH, Choi CH, Park JK, Kim HJ. | Sci Rep | 10.1038/s41598-019-38982-0 | 2019 | | |
| Metabolism | Specific Binding Peptides from Rv3632: A Strategy for Blocking Mycobacterium tuberculosis Entry to Target Cells? | Sanchez-Barinas CD, Ocampo M, Tabares L, Bermudez M, Patarroyo MA, Patarroyo ME. | Biomed Res Int | 10.1155/2019/8680935 | 2019 | |
| Synthesis of Chalcones Derivatives and Their Biological Activities: A Review. | Elkanzi NAA, Hrichi H, Alolayan RA, Derafa W, Zahou FM, Bakr RB. | ACS Omega | 10.1021/acsomega.2c01779 | 2022 | | |
| Molecular detection of rifampin, isoniazid, and ofloxacin resistance in Iranian isolates of Mycobacterium tuberculosis by high-resolution melting analysis. | Sirous M, Khosravi AD, Tabandeh MR, Salmanzadeh S, Ahmadkhosravi N, Amini S. | Infect Drug Resist | 10.2147/idr.s178831 | 2018 | | |
| Pathogenicity | Comparison of In Vitro Activity and MIC Distributions between the Novel Oxazolidinone Delpazolid and Linezolid against Multidrug-Resistant and Extensively Drug-Resistant Mycobacterium tuberculosis in China. | Zong Z, Jing W, Shi J, Wen S, Zhang T, Huo F, Shang Y, Liang Q, Huang H, Pang Y. | Antimicrob Agents Chemother | 10.1128/aac.00165-18 | 2018 | |
| Brocaeloid D, a novel compound isolated from a wheat pathogenic fungus, Microdochium majus 99049. | Zhang J, Wang Z, Song Z, Karthik L, Hou C, Zhu G, Jiang L, Han J, Ma R, Li L, Zhang L, Liu X, Hsiang T. | Synth Syst Biotechnol | 10.1016/j.synbio.2019.09.001 | 2019 | | |
| Recent advances on anticancer and antimicrobial activities of directly-fluorinated five-membered heterocycles and their benzo-fused systems. | Abbas AA, Farghaly TA, Dawood KM. | RSC Adv | 10.1039/d4ra01387e | 2024 | | |
| Fusion of Dendritic Cells Activating Rv2299c Protein Enhances the Protective Immunity of Ag85B-ESAT6 Vaccine Candidate against Tuberculosis. | Back YW, Bae HS, Choi HG, Binh DT, Son YJ, Choi S, Kim HJ. | Pathogens | 10.3390/pathogens9110865 | 2020 | | |
| Comparative analysis of the leprosy detection rate regarding its clinical spectrum through PCR using the 16S rRNA gene: a scientometrics and meta-analysis. | Silva MJA, Brasil TP, Silva CS, Frota CC, Sardinha DM, Figueira LRT, Neves KAS, Dos Santos EC, Lima KVB, Ghisi NC, Lima LNGC. | Front Microbiol | 10.3389/fmicb.2024.1497319 | 2024 | | |
| Genetics | Characterization of Genomic Variants Associated with Resistance to Bedaquiline and Delamanid in Naive Mycobacterium tuberculosis Clinical Strains. | Battaglia S, Spitaleri A, Cabibbe AM, Meehan CJ, Utpatel C, Ismail N, Tahseen S, Skrahina A, Alikhanova N, Mostofa Kamal SM, Barbova A, Niemann S, Groenheit R, Dean AS, Zignol M, Rigouts L, Cirillo DM. | J Clin Microbiol | 10.1128/jcm.01304-20 | 2020 | |
| Pathogenicity | Pyrazinamide triggers degradation of its target aspartate decarboxylase. | Gopal P, Sarathy JP, Yee M, Ragunathan P, Shin J, Bhushan S, Zhu J, Akopian T, Kandror O, Lim TK, Gengenbacher M, Lin Q, Rubin EJ, Gruber G, Dick T. | Nat Commun | 10.1038/s41467-020-15516-1 | 2020 | |
| Design and Synthesis of Some Novel Fluorobenzimidazoles Substituted with Structural Motifs Present in Physiologically Active Natural Products for Antitubercular Activity. | Nandha B, Nargund LG, Nargund SL, Bhat K. | Iran J Pharm Res | 2017 | | ||
| Enzymology | Multiparameter Responses to Tedizolid Monotherapy and Moxifloxacin Combination Therapy Models of Children With Intracellular Tuberculosis. | Deshpande D, Srivastava S, Nuermberger E, Koeuth T, Martin KR, Cirrincione KN, Lee PS, Gumbo T. | Clin Infect Dis | 10.1093/cid/ciy612 | 2018 | |
| Enzymology | Evaluation of GeneXpert MTB/RIF for detecting Mycobacterium tuberculosis in a hospital in China. | Tang T, Liu F, Lu X, Huang Q. | J Int Med Res | 10.1177/0300060517698618 | 2017 | |
| Pathogenicity | Effects of the encapsulation of usnic acid into liposomes and interactions with antituberculous agents against multidrug-resistant tuberculosis clinical isolates. | Ferraz-Carvalho RS, Pereira MA, Linhares LA, Lira-Nogueira MC, Cavalcanti IM, Santos-Magalhaes NS, Montenegro LM. | Mem Inst Oswaldo Cruz | 10.1590/0074-02760150454 | 2016 | |
| Metabolism | Synthesis and biological evaluation of orally active prodrugs and analogs of para-aminosalicylic acid (PAS). | Hegde PV, Howe MD, Zimmerman MD, Boshoff HIM, Sharma S, Remache B, Jia Z, Pan Y, Baughn AD, Dartois V, Aldrich CC. | Eur J Med Chem | 10.1016/j.ejmech.2022.114201 | 2022 | |
| SIRPalpha maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis. | Wang D, Lin Y, Xu F, Zhang H, Zhu X, Liu Z, Hu Y, Dong G, Sun B, Yu Y, Ma G, Tang Z, Legarda D, Ting A, Liu Y, Hou J, Dong L, Xiong H. | EBioMedicine | 10.1016/j.ebiom.2022.104278 | 2022 | | |
| Metabolism | Potency boost of a Mycobacterium tuberculosis dihydrofolate reductase inhibitor by multienzyme F420H2-dependent reduction. | Aragaw WW, Lee BM, Yang X, Zimmerman MD, Gengenbacher M, Dartois V, Chui WK, Jackson CJ, Dick T. | Proc Natl Acad Sci U S A | 10.1073/pnas.2025172118 | 2021 | |
| Pathogenicity | Molecular Investigation of Resistance to Second-Line Injectable Drugs in Multidrug-Resistant Clinical Isolates of Mycobacterium tuberculosis in France. | Brossier F, Pham A, Bernard C, Aubry A, Jarlier V, Veziris N, Sougakoff W, CNR-MyRMA. | Antimicrob Agents Chemother | 10.1128/aac.01299-16 | 2017 | |
| Pathogenicity | Antimicrobial Activity of Cyclic-Monomeric and Dimeric Derivatives of the Snail-Derived Peptide Cm-p5 against Viral and Multidrug-Resistant Bacterial Strains. | Gonzalez-Garcia M, Morales-Vicente F, Pico ED, Garay H, Rivera DG, Grieshober M, Raluca Olari L, Gross R, Conzelmann C, Kruger F, Zech F, Prelli Bozzo C, Muller JA, Zelikin A, Raber H, Kubiczek D, Rosenau F, Munch J, Stenger S, Spellerberg B, Franco OL, Rodriguez Alfonso AA, Standker L, Otero-Gonzalez AJ. | Biomolecules | 10.3390/biom11050745 | 2021 | |
| Sensitive detection of the IS6110 sequence of Mycobacterium tuberculosis complex based on PCR-magnetic bead ELISA. | Kyaw SP, Hanthamrongwit J, Jangpatarapongsa K, Khaenam P, Leepiyasakulchai C. | RSC Adv | 10.1039/c8ra06599c | 2018 | | |
| Evaluation of crystal violet decolorization assay and resazurin microplate assay for antimycobacterial screening. | Rakhmawatie MD, Wibawa T, Lisdiyanti P, Pratiwi WR, Mustofa. | Heliyon | 10.1016/j.heliyon.2019.e02263 | 2019 | | |
| Antimicrobial activity, phytochemical characterization and gas chromatography-mass spectrometry analysis of Aspilia pluriseta Schweinf. extracts. | Njeru SN, Muema JM. | Heliyon | 10.1016/j.heliyon.2020.e05195 | 2020 | | |
| Host MKRN1-Mediated Mycobacterial PPE Protein Ubiquitination Suppresses Innate Immune Response. | Dou Y, Xie Y, Zhang L, Liu S, Xu D, Wei Y, Li Y, Zhang XL. | Front Immunol | 10.3389/fimmu.2022.880315 | 2022 | | |
| Identification of N-(2-Phenoxyethyl)imidazo[1,2-a]pyridine-3-carboxamides as New Antituberculosis Agents. | Wu Z, Lu Y, Li L, Zhao R, Wang B, Lv K, Liu M, You X. | ACS Med Chem Lett | 10.1021/acsmedchemlett.6b00330 | 2016 | | |
| Metabolism | Vitamin B1 Helps to Limit Mycobacterium tuberculosis Growth via Regulating Innate Immunity in a Peroxisome Proliferator-Activated Receptor-gamma-Dependent Manner. | Hu S, He W, Du X, Huang Y, Fu Y, Yang Y, Hu C, Li S, Wang Q, Wen Q, Zhou X, Zhou C, Zhong XP, Ma L. | Front Immunol | 10.3389/fimmu.2018.01778 | 2018 | |
| Biotechnology | Coumarins as Fungal Metabolites with Potential Medicinal Properties. | Tsivileva OM, Koftin OV, Evseeva NV. | Antibiotics (Basel) | 10.3390/antibiotics11091156 | 2022 | |
| Pathogenicity | Meropenem-clavulanic acid has high in vitro activity against multidrug-resistant Mycobacterium tuberculosis. | Davies Forsman L, Giske CG, Bruchfeld J, Schon T, Jureen P, Angeby K. | Antimicrob Agents Chemother | 10.1128/aac.00171-15 | 2015 | |
| Metabolism | 1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in Mycobacterium tuberculosis. | Khonde LP, Muller R, Boyle GA, Reddy V, Nchinda AT, Eyermann CJ, Fienberg S, Singh V, Myrick A, Abay E, Njoroge M, Lawrence N, Su Q, Myers TG, Boshoff HIM, Barry CE, Sirgel FA, van Helden PD, Massoudi LM, Robertson GT, Lenaerts AJ, Basarab GS, Ghorpade SR, Chibale K. | J Med Chem | 10.1021/acs.jmedchem.1c00837 | 2021 | |
| Enzymology | Multiplex-PCR for differentiation of Mycobacterium bovis from Mycobacterium tuberculosis complex. | Spositto FL, Campanerut PA, Ghiraldi LD, Leite CQ, Hirata MH, Hirata RD, Siqueira VL, Cardoso RF. | Braz J Microbiol | 10.1590/s1517-83822014000300012 | 2014 | |
| Therapeutic Modulation of Arginase with nor-NOHA Alters Immune Responses in Experimental Mouse Models of Pulmonary Tuberculosis including in the Setting of Human Immunodeficiency Virus (HIV) Co-Infection. | Chauhan S, Nusbaum RJ, Huante MB, Holloway AJ, Endsley MA, Gelman BB, Lisinicchia JG, Endsley JJ. | Trop Med Infect Dis | 10.3390/tropicalmed9060129 | 2024 | | |
| High Sequence Variability of the ppE18 Gene of Clinical Mycobacterium tuberculosis Complex Strains Potentially Impacts Effectivity of Vaccine Candidate M72/AS01E. | Homolka S, Ubben T, Niemann S. | PLoS One | 10.1371/journal.pone.0152200 | 2016 | | |
| Pathogenicity | MDR M. tuberculosis outbreak clone in Eswatini missed by Xpert has elevated bedaquiline resistance dated to the pre-treatment era. | Beckert P, Sanchez-Padilla E, Merker M, Dreyer V, Kohl TA, Utpatel C, Koser CU, Barilar I, Ismail N, Omar SV, Klopper M, Warren RM, Hoffmann H, Maphalala G, Ardizzoni E, de Jong BC, Kerschberger B, Schramm B, Andres S, Kranzer K, Maurer FP, Bonnet M, Niemann S. | Genome Med | 10.1186/s13073-020-00793-8 | 2020 | |
| Expression and Clinical Significance of lncRNA NEAT1 in Patients with Spinal Tuberculosis. | Zheng J, Wang X, Shi J, Tian J, Chang X, Wang X, Ye Q. | Dis Markers | 10.1155/2022/5748756 | 2022 | | |
| Comparison of immunogenicity and vaccine efficacy between heat-shock proteins, HSP70 and GrpE, in the DnaK operon of Mycobacterium tuberculosis. | Kim WS, Kim JS, Kim HM, Kwon KW, Eum SY, Shin SJ. | Sci Rep | 10.1038/s41598-018-32799-z | 2018 | | |
| Enzymology | Development of a One-Step Multiplex PCR Assay for Differential Detection of Major Mycobacterium Species. | Chae H, Han SJ, Kim SY, Ki CS, Huh HJ, Yong D, Koh WJ, Shin SJ. | J Clin Microbiol | 10.1128/jcm.00549-17 | 2017 | |
| Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity. | Dos Santos Fernandes GF, de Souza PC, Moreno-Viguri E, Santivanez-Veliz M, Paucar R, Perez-Silanes S, Chegaev K, Guglielmo S, Lazzarato L, Fruttero R, Man Chin C, da Silva PB, Chorilli M, Solcia MC, Ribeiro CM, Silva CSP, Marino LB, Bosquesi PL, Hunt DM, de Carvalho LPS, de Souza Costa CA, Cho SH, Wang Y, Franzblau SG, Pavan FR, Dos Santos JL. | J Med Chem | 10.1021/acs.jmedchem.7b01332 | 2017 | | |
| Potential cannabidiol (CBD) repurposing as antibacterial and promising therapy of CBD plus polymyxin B (PB) against PB-resistant gram-negative bacilli. | Abichabki N, Zacharias LV, Moreira NC, Bellissimo-Rodrigues F, Moreira FL, Benzi JRL, Ogasawara TMC, Ferreira JC, Ribeiro CM, Pavan FR, Pereira LRL, Brancini GTP, Braga GUL, Zuardi AW, Hallak JEC, Crippa JAS, Lanchote VL, Canton R, Darini ALC, Andrade LN. | Sci Rep | 10.1038/s41598-022-10393-8 | 2022 | | |
| Enzymology | Association between pncA gene mutations, pyrazinamidase activity, and pyrazinamide susceptibility testing in Mycobacterium tuberculosis. | Aono A, Chikamatsu K, Yamada H, Kato T, Mitarai S. | Antimicrob Agents Chemother | 10.1128/aac.02394-14 | 2014 | |
| Pathogenicity | Anti-Mycobacterium tuberculosis Activity of Esters of Quinoxaline 1,4-Di-N-Oxide. | Palos I, Luna-Herrera J, Lara-Ramirez EE, Loera-Piedra A, Fernandez-Ramirez E, Aguilera-Arreola MG, Paz-Gonzalez AD, Monge A, Wan B, Franzblau S, Rivera G. | Molecules | 10.3390/molecules23061453 | 2018 | |
| Pathogenicity | Comparison of the Efficacy of Two Novel Antitubercular Agents in Free and Liposome-Encapsulated Formulations. | Kosa N, Zolcsak A, Voszka I, Csik G, Horvati K, Horvath L, Bosze S, Herenyi L. | Int J Mol Sci | 10.3390/ijms22052457 | 2021 | |
| Pathogenicity | Efficacy Versus Hepatotoxicity of High-dose Rifampin, Pyrazinamide, and Moxifloxacin to Shorten Tuberculosis Therapy Duration: There Is Still Fight in the Old Warriors Yet! | Srivastava S, Deshpande D, Magombedze G, Gumbo T. | Clin Infect Dis | 10.1093/cid/ciy627 | 2018 | |
| Enzymology | Blocking Bacterial Naphthohydroquinone Oxidation and ADP-Ribosylation Improves Activity of Rifamycins against Mycobacterium abscessus. | Ganapathy US, Lan T, Krastel P, Lindman M, Zimmerman MD, Ho H, Sarathy JP, Evans JC, Dartois V, Aldrich CC, Dick T. | Antimicrob Agents Chemother | 10.1128/aac.00978-21 | 2021 | |
| Metabolism | Advances in Research on Bioactivity, Toxicity, Metabolism, and Pharmacokinetics of Usnic Acid In Vitro and In Vivo. | Wang H, Xuan M, Huang C, Wang C. | Molecules | 10.3390/molecules27217469 | 2022 | |
| Synthesis and evaluation of a pyrazinoic acid prodrug in Mycobacterium tuberculosis. | Fernandes JP, Pavan FR, Leite CQ, Felli VM. | Saudi Pharm J | 10.1016/j.jsps.2013.12.005 | 2014 | | |
| Imidazoles Induce Reactive Oxygen Species in Mycobacterium tuberculosis Which Is Not Associated with Cell Death. | Howell Wescott HA, Roberts DM, Allebach CL, Kokoczka R, Parish T. | ACS Omega | 10.1021/acsomega.6b00212 | 2017 | | |
| In Vitro Activity of the Sudapyridine (WX-081) against Non-Tuberculous Mycobacteria Isolated in Beijing, China. | Zhu R, Shang Y, Chen S, Xiao H, Ren R, Wang F, Xue Y, Li L, Li Y, Chu N, Huang H. | Microbiol Spectr | 10.1128/spectrum.01372-22 | 2022 | | |
| Antibacterial and Antitubercular Activities of Cinnamylideneacetophenones. | Polaquini CR, Torrezan GS, Santos VR, Nazare AC, Campos DL, Almeida LA, Silva IC, Ferreira H, Pavan FR, Duque C, Regasini LO. | Molecules | 10.3390/molecules22101685 | 2017 | | |
| Mutations in fbiD (Rv2983) as a Novel Determinant of Resistance to Pretomanid and Delamanid in Mycobacterium tuberculosis. | Rifat D, Li SY, Ioerger T, Shah K, Lanoix JP, Lee J, Bashiri G, Sacchettini J, Nuermberger E. | Antimicrob Agents Chemother | 10.1128/aac.01948-20 | 2020 | | |
| The burden of pre-extensively and extensively drug-resistant tuberculosis among MDR-TB patients in the Amhara region, Ethiopia. | Shibabaw A, Gelaw B, Gebreyes W, Robinson R, Wang SH, Tessema B. | PLoS One | 10.1371/journal.pone.0229040 | 2020 | | |
| Pathogenicity | Antibacterial activity of selected Cameroonian dietary spices ethno-medically used against strains of Mycobacterium tuberculosis. | Tekwu EM, Askun T, Kuete V, Nkengfack AE, Nyasse B, Etoa FX, Beng VP. | J Ethnopharmacol | 10.1016/j.jep.2012.05.003 | 2012 | |
| Dynamic microfluidic single-cell screening identifies pheno-tuning compounds to potentiate tuberculosis therapy. | Mistretta M, Cimino M, Campagne P, Volant S, Kornobis E, Hebert O, Rochais C, Dallemagne P, Lecoutey C, Tisnerat C, Lepailleur A, Ayotte Y, LaPlante SR, Gangneux N, Zahorszka M, Kordulakova J, Vichier-Guerre S, Bonhomme F, Pokorny L, Albert M, Tinevez JY, Manina G. | Nat Commun | 10.1038/s41467-024-48269-2 | 2024 | | |
| Pathogenicity | Duration of pretomanid/moxifloxacin/pyrazinamide therapy compared with standard therapy based on time-to-extinction mathematics. | Srivastava S, Deshpande D, Magombedze G, van Zyl J, Cirrincione K, Martin K, Bendet P, Berg A, Hanna D, Romero K, Hermann D, Gumbo T. | J Antimicrob Chemother | 10.1093/jac/dkz460 | 2020 | |
| Metabolism | Diarylethenes Display In Vitro Anti-TB Activity and Are Efficient Hits Targeting the Mycobacterium tuberculosis HU Protein. | Suarez MA, Valencia J, Cadena CC, Maiti R, Datta C, Puerto G, Isaza JH, San Juan H, Nagaraja V, Guzman JD. | Molecules | 10.3390/molecules22081245 | 2017 | |
| Clinical diagnostic value of simultaneous amplification and testing for the diagnosis of sputum-scarce pulmonary tuberculosis. | Yan L, Zhang Q, Xiao H. | BMC Infect Dis | 10.1186/s12879-017-2647-7 | 2017 | | |
| Improving Antimicrobial Activity and Physico-Chemical Properties by Isosteric Replacement of 2-Aminothiazole with 2-Aminooxazole. | Juhas M, Bachtikova A, Nawrot DE, Hatokova P, Pallabothula VSK, Diepoltova A, Jandourek O, Barta P, Konecna K, Paterova P, Sestak V, Zitko J. | Pharmaceuticals (Basel) | 10.3390/ph15050580 | 2022 | | |
| Genetics | Genomic Analysis Identifies Mutations Concerning Drug-Resistance and Beijing Genotype in Multidrug-Resistant Mycobacterium tuberculosis Isolated From China. | Wan L, Liu H, Li M, Jiang Y, Zhao X, Liu Z, Wan K, Li G, Guan CX. | Front Microbiol | 10.3389/fmicb.2020.01444 | 2020 | |
| Pathogenicity | Vitamin B5 Reduces Bacterial Growth via Regulating Innate Immunity and Adaptive Immunity in Mice Infected with Mycobacterium tuberculosis. | He W, Hu S, Du X, Wen Q, Zhong XP, Zhou X, Zhou C, Xiong W, Gao Y, Zhang S, Wang R, Yang J, Ma L. | Front Immunol | 10.3389/fimmu.2018.00365 | 2018 | |
| Metabolism | The Expression of lncRNA NEAT1 in Human Tuberculosis and Its Antituberculosis Effect. | Huang S, Huang Z, Luo Q, Qing C. | Biomed Res Int | 10.1155/2018/9529072 | 2018 | |
| Novel Halogenated Pyrazine-Based Chalcones as Potential Antimicrobial Drugs. | Kucerova-Chlupacova M, Vyskovska-Tyllova V, Richterova-Finkova L, Kunes J, Buchta V, Vejsova M, Paterova P, Semelkova L, Jandourek O, Opletalova V. | Molecules | 10.3390/molecules21111421 | 2016 | | |
| Novel antimycobacterial C-21 amide derivatives of the antibiotic fusidic acid: synthesis, pharmacological evaluation and rationalization of media-dependent activity using molecular docking studies in the binding site of human serum albumin. | Dziwornu GA, Kamunya S, Ntsabo T, Chibale K. | Medchemcomm | 10.1039/c9md00161a | 2019 | | |
| High Resolution Melting Curve Analysis for Rapid Detection of Streptomycin and Ethambutol Resistance in Mycobacterium tuberculosis. | Rezaei F, Haeili M, Fooladi AI, Feizabadi MM. | Maedica (Bucur) | 2017 | | ||
| Genetics | Prevalence, risk and genetic characteristics of drug-resistant tuberculosis in a tertiary care tuberculosis hospital in China. | Zhao LL, Huang MX, Xiao TY, Liu HC, Li MC, Zhao XQ, Liu ZG, Jiang Y, Wan KL. | Infect Drug Resist | 10.2147/idr.s209971 | 2019 | |
| Superior Efficacy of a TBI-166, Bedaquiline, and Pyrazinamide Combination Regimen in a Murine Model of Tuberculosis. | Ding Y, Zhu H, Fu L, Zhang W, Wang B, Guo S, Chen X, Wang N, Liu H, Lu Y. | Antimicrob Agents Chemother | 10.1128/aac.00658-22 | 2022 | | |
| A small mycobacteriophage-derived peptide and its improved isomer restrict mycobacterial infection via dual mycobactericidal-immunoregulatory activities. | Yang Y, Liu Z, He X, Yang J, Wu J, Yang H, Li M, Qian Q, Lai R, Xu W, Wei L. | J Biol Chem | 10.1074/jbc.ra118.006968 | 2019 | | |
| Pathogenicity | CD44 receptor targeted nanoparticles augment immunity against tuberculosis in mice. | Singh VK, Chau E, Mishra A, DeAnda A, Hegde VL, Sastry JK, Haviland D, Jagannath C, Godin B, Khan A. | J Control Release | 10.1016/j.jconrel.2022.07.040 | 2022 | |
| Performance of an in-house real-time polymerase chain reaction for identification of Mycobacterium tuberculosis isolates in laboratory routine diagnosis from a high burden setting. | Gallo JF, Pinhata JM, Chimara E, Goncalves MG, Fukasawa LO, Oliveira RS. | Mem Inst Oswaldo Cruz | 10.1590/0074-02760160048 | 2016 | | |
| Metabolism | Mycobacterium tuberculosis induces connective tissue growth factor expression through the TLR2-JNK-AP-1 pathway in human lung fibroblasts. | Lee HS, Hua HS, Wang CH, Yu MC, Chen BC, Lin CH. | FASEB J | 10.1096/fj.201900487r | 2019 | |
| Potency Increase of Spiroketal Analogs of Membrane Inserting Indolyl Mannich Base Antimycobacterials Is Due to Acquisition of MmpL3 Inhibition. | Li M, Phua ZY, Xi Y, Xu Z, Nyantakyi SA, Li W, Jackson M, Wong MW, Lam Y, Chng SS, Go ML, Dick T. | ACS Infect Dis | 10.1021/acsinfecdis.0c00121 | 2020 | | |
| Enzymology | Highly Sensitive Detection of Isoniazid Heteroresistance in Mycobacterium tuberculosis by DeepMelt Assay. | Liang B, Tan Y, Li Z, Tian X, Du C, Li H, Li G, Yao X, Wang Z, Xu Y, Li Q. | J Clin Microbiol | 10.1128/jcm.01239-17 | 2018 | |
| Mycobacterium Growth Inhibition Assay of Human Alveolar Macrophages as a Correlate of Immune Protection Following Mycobacterium bovis Bacille Calmette-Guérin Vaccination. | Radloff J, Heyckendorf J, van der Merwe L, Sanchez Carballo P, Reiling N, Richter E, Lange C, Kalsdorf B. | Front Immunol | 10.3389/fimmu.2018.01708 | 2018 | | |
| Synthesis, antitubercular and anticancer activity of new Baylis-Hillman adduct-derived N-cinnamyl-substituted isatin derivatives. | Kumar SB, Ravinder M, Kishore G, Jayathirtha Rao V, Yogeeswari P, Sriram D. | Med Chem Res | 10.1007/s00044-013-0787-x | 2014 | | |
| Pathogenicity | Evaluation of the microscopic observation drug susceptibility assay for detection of Mycobacterium tuberculosis resistance to pyrazinamide. | Ghiraldi LD, Campanerut PA, Spositto FL, Sato DN, Leite CQ, Hirata M, Hirata RD, Cardoso RF. | Clin Microbiol Infect | 10.1111/j.1469-0691.2011.03508.x | 2011 | |
| Antibacterial effects of biologically active ingredients in hop provide promising options to fight infections by pathogens including multi-drug resistant bacteria. | Fahle A, Bereswill S, Heimesaat MM. | Eur J Microbiol Immunol (Bp) | 10.1556/1886.2022.00006 | 2022 | | |
| Pathogenicity | Mycobacterium tuberculosis H37Rv LpqG Protein Peptides Can Inhibit Mycobacterial Entry through Specific Interactions. | Sanchez-Barinas CD, Ocampo M, Vanegas M, Castaneda-Ramirez JJ, Patarroyo MA, Patarroyo ME. | Molecules | 10.3390/molecules23030526 | 2018 | |
| Genetic diversity and drug resistance pattern of Mycobacterium tuberculosis strains isolated from pulmonary tuberculosis patients in the Benishangul Gumuz region and its surroundings, Northwest Ethiopia. | Lobie TA, Woldeamanuel Y, Asrat D, Beyene D, Bjoras M, Aseffa A. | PLoS One | 10.1371/journal.pone.0231320 | 2020 | | |
| Pathogenicity | In Vitro Activity and MIC of Sitafloxacin against Multidrug-Resistant and Extensively Drug-Resistant Mycobacterium tuberculosis Isolated in Thailand. | Leechawengwongs M, Prammananan T, Jaitrong S, Billamas P, Makhao N, Thamnongdee N, Thanormchat A, Phurattanakornkul A, Rattanarangsee S, Ratanajaraya C, Disratthakit A, Chaiprasert A. | Antimicrob Agents Chemother | 10.1128/aac.00825-17 | 2018 | |
| Enzymology | Mycobacterium tuberculosis infection of domesticated Asian elephants, Thailand. | Angkawanish T, Wajjwalku W, Sirimalaisuwan A, Mahasawangkul S, Kaewsakhorn T, Boonsri K, Rutten VP. | Emerg Infect Dis | 10.3201/eid1612.100862 | 2010 | |
| Fragmentation Study, Dual Anti-Bactericidal and Anti-Viral Effects and Molecular Docking of Cobalt(III) Complexes. | Fernandes LP, Silva JMB, Martins DOS, Santiago MB, Martins CHG, Jardim ACG, Oliveira GS, Pivatto M, Souza RAC, Franca EF, Deflon VM, Machado AEH, Oliveira CG. | Int J Mol Sci | 10.3390/ijms21218355 | 2020 | | |
| Mutations in Streptomycin Resistance Genes and Their Relationship to Streptomycin Resistance and Lineage of Mycobacterium tuberculosis Thai Isolates. | Hlaing YM, Tongtawe P, Tapchaisri P, Thanongsaksrikul J, Thawornwan U, Archanachan B, Srimanote P. | Tuberc Respir Dis (Seoul) | 10.4046/trd.2017.80.2.159 | 2017 | | |
| Enzymology | First insights on the genetic diversity of MDR Mycobacterium tuberculosis in Lebanon. | Panossian B, Salloum T, Araj GF, Khazen G, Tokajian S. | BMC Infect Dis | 10.1186/s12879-018-3626-3 | 2018 | |
| Antimicrobial Lavandulylated Flavonoids from a Sponge-Derived Streptomyces sp. G248 in East Vietnam Sea. | Cao DD, Trinh TTV, Mai HDT, Vu VN, Le HM, Thi QV, Nguyen MA, Duong TT, Tran DT, Chau VM, Ma R, Shetye G, Cho S, Murphy BT, Pham VC. | Mar Drugs | 10.3390/md17090529 | 2019 | | |
| Plasma concentrations of second-line antituberculosis drugs in relation to minimum inhibitory concentrations in multidrug-resistant tuberculosis patients in China: a study protocol of a prospective observational cohort study. | Davies Forsman L, Niward K, Hu Y, Zheng R, Zheng X, Ke R, Cai W, Hong C, Li Y, Gao Y, Werngren J, Paues J, Kuhlin J, Simonsson USH, Eliasson E, Alffenaar JW, Mansjo M, Hoffner S, Xu B, Schon T, Bruchfeld J. | BMJ Open | 10.1136/bmjopen-2018-023899 | 2018 | | |
| Pathogenicity | Assessing the Combined Antibacterial Effect of Isoniazid and Rifampin on Four Mycobacterium tuberculosis Strains Using In Vitro Experiments and Response-Surface Modeling. | Genestet C, Ader F, Pichat C, Lina G, Dumitrescu O, Goutelle S. | Antimicrob Agents Chemother | 10.1128/aac.01413-17 | 2018 | |
| Hydrazide-hydrazones as potential antimicrobial agents: overview of the literature since 2010. | Popiolek L. | Med Chem Res | 10.1007/s00044-016-1756-y | 2017 | | |
| Metabolism | Discovery of a novel dehydratase of the fatty acid synthase type II critical for ketomycolic acid biosynthesis and virulence of Mycobacterium tuberculosis. | Lefebvre C, Frigui W, Slama N, Lauzeral-Vizcaino F, Constant P, Lemassu A, Parish T, Eynard N, Daffe M, Brosch R, Quemard A. | Sci Rep | 10.1038/s41598-020-58967-8 | 2020 | |
| Metabolism | WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis. | Brandenburg J, Marwitz S, Tazoll SC, Waldow F, Kalsdorf B, Vierbuchen T, Scholzen T, Gross A, Goldenbaum S, Holscher A, Hein M, Linnemann L, Reimann M, Kispert A, Leitges M, Rupp J, Lange C, Niemann S, Behrends J, Goldmann T, Heine H, Schaible UE, Holscher C, Schwudke D, Reiling N. | J Clin Invest | 10.1172/jci141833 | 2021 | |
| Rifapentine Polylactic Acid Sustained-Release Microsphere Complex for Spinal Tuberculosis Therapy: Preparation, in vitro and in vivo Studies. | Wang Z, Maimaitiaili A, Wang T, Song X. | Infect Drug Resist | 10.2147/idr.s304864 | 2021 | | |
| Enzymology | Comparison of the genedia MTB detection kit and the cobas TaqMan MTB assay for detection of Mycobacterium tuberculosis in respiratory specimens. | Huh HJ, Kwon HJ, Ki CS, Lee NY. | J Clin Microbiol | 10.1128/jcm.03163-14 | 2015 | |
| Phylogeny | New Mycobacterium tuberculosis Complex Sublineage, Brazzaville, Congo. | Malm S, Linguissi LS, Tekwu EM, Vouvoungui JC, Kohl TA, Beckert P, Sidibe A, Rusch-Gerdes S, Madzou-Laboum IK, Kwedi S, Penlap Beng V, Frank M, Ntoumi F, Niemann S. | Emerg Infect Dis | 10.3201/eid2303.160679 | 2017 | |
| Crystal structures and Hirshfeld surface analyses of (E)-N'-benzyl-idene-2-oxo-2H-chromene-3-carbo-hydrazide and the disordered hemi-DMSO solvate of (E)-2-oxo-N'-(3,4,5-trimeth-oxybenzyl-idene)-2H-chromene-3-carbohydrazide: lattice energy and inter-molecular inter-action energy calculations for the former. | Gomes LR, Low JN, Wardell JL, Capelini C, Camara VRF, da Silva EF, Carvalho SA. | Acta Crystallogr E Crystallogr Commun | 10.1107/s2056989019012015 | 2019 | | |
| Pathogenicity | Synergy between Circular Bacteriocin AS-48 and Ethambutol against Mycobacterium tuberculosis. | Aguilar-Perez C, Gracia B, Rodrigues L, Vitoria A, Cebrian R, Deboosere N, Song OR, Brodin P, Maqueda M, Ainsa JA. | Antimicrob Agents Chemother | 10.1128/aac.00359-18 | 2018 | |
| Pathogenicity | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. | Sirisha K, Bikshapathi D, Achaiah G, Reddy VM. | Eur J Med Chem | 10.1016/j.ejmech.2011.02.003 | 2011 | |
| Dual-target inhibitors of mycobacterial aminoacyl-tRNA synthetases among N-benzylidene-N'-thiazol-2-yl-hydrazines. | Kovalenko OP, Volynets GP, Rybak MY, Starosyla SA, Gudzera OI, Lukashov SS, Bdzhola VG, Yarmoluk SM, Boshoff HI, Tukalo MA. | Medchemcomm | 10.1039/c9md00347a | 2019 | | |
| Synthesis and Characterization of Phenylalanine Amides Active against Mycobacterium abscessus and Other Mycobacteria. | Lang M, Ganapathy US, Mann L, Abdelaziz R, Seidel RW, Goddard R, Sequenzia I, Hoenke S, Schulze P, Aragaw WW, Csuk R, Dick T, Richter A. | J Med Chem | 10.1021/acs.jmedchem.3c00009 | 2023 | | |
| Metabolism | Rapid detection of resistance to pyrazinamide in Mycobacterium tuberculosis using the resazurin microtitre assay. | Campanerut PA, Ghiraldi LD, Spositto FL, Sato DN, Leite CQ, Hirata MH, Hirata RD, Cardoso RF. | J Antimicrob Chemother | 10.1093/jac/dkr057 | 2011 | |
| Enzymology | Population Pharmacokinetics and Dose Evaluation of Cycloserine among Patients with Multidrug-Resistant Tuberculosis under Standardized Treatment Regimens. | Zhu Y, Zhu L, Davies Forsman L, Paues J, Werngren J, Niward K, Schon T, Bruchfeld J, Xiong H, Alffenaar JW, Hu Y. | Antimicrob Agents Chemother | 10.1128/aac.01700-22 | 2023 | |
| Rolling circle amplification for direct detection of rpoB gene mutations in Mycobacterium tuberculosis isolates from clinical specimens. | Chen X, Wang B, Yang W, Kong F, Li C, Sun Z, Jelfs P, Gilbert GL. | J Clin Microbiol | 10.1128/jcm.00065-14 | 2014 | | |
| Effective delivery of the anti-mycobacterial peptide NZX in mesoporous silica nanoparticles. | Tenland E, Pochert A, Krishnan N, Umashankar Rao K, Kalsum S, Braun K, Glegola-Madejska I, Lerm M, Robertson BD, Linden M, Godaly G. | PLoS One | 10.1371/journal.pone.0212858 | 2019 | | |
| Pathogenicity | Antimycobacterial activity of 2-phenoxy-1-phenylethanone, a synthetic analogue of neolignan, entrapped in polymeric microparticles. | Minarini PR, de Souza AO, Soares EG, Barata LE, Silva CL, Bentley MV. | Drug Dev Ind Pharm | 10.3109/03639045.2011.598535 | 2012 | |
| Mycobacterial biomaterials and resources for researchers. | Hazbon MH, Rigouts L, Schito M, Ezewudo M, Kudo T, Itoh T, Ohkuma M, Kiss K, Wu L, Ma J, Hamada M, Strong M, Salfinger M, Daley CL, Nick JA, Lee JS, Rastogi N, Couvin D, Hurtado-Ortiz R, Bizet C, Suresh A, Rodwell T, Albertini A, Lacourciere KA, Deheer-Graham A, Alexander S, Russell JE, Bradford R, Riojas MA. | Pathog Dis | 10.1093/femspd/fty042 | 2018 | | |
| Pathogenicity | Synthesis and Anti-Mycobacterium tuberculosis Evaluation of Aza-Stilbene Derivatives. | Pavan FR, de Carvalho GS, da Silva AD, Leite CQ. | ScientificWorldJournal | 10.1100/tsw.2011.110 | 2011 | |
| Enzymology | Novel vaccine potential of Rv3131, a DosR regulon-encoded putative nitroreductase, against hyper-virulent Mycobacterium tuberculosis strain K. | Kwon KW, Kim WS, Kim H, Han SJ, Hahn MY, Lee JS, Nam KT, Cho SN, Shin SJ. | Sci Rep | 10.1038/srep44151 | 2017 | |
| Pathogenicity | Evaluation of the BD Bactec MGIT 320 system for detection of mycobacteria and drug susceptibility testing of Mycobacterium tuberculosis. | Duque A, Lin SY, Desmond E, Rienthong S, Rienthong D, Boonin C. | J Clin Microbiol | 10.1128/jcm.01357-13 | 2013 | |
| Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis. | Plumlee CR, Duffy FJ, Gern BH, Delahaye JL, Cohen SB, Stoltzfus CR, Rustad TR, Hansen SG, Axthelm MK, Picker LJ, Aitchison JD, Sherman DR, Ganusov VV, Gerner MY, Zak DE, Urdahl KB. | Cell Host Microbe | 10.1016/j.chom.2020.10.003 | 2021 | | |
| Pathogenicity | Synthesis, evaluation, molecular docking, and molecular dynamics studies of novel N-(4-[pyridin-2-yloxy]benzyl)arylamine derivatives as potential antitubercular agents. | Verma R, Boshoff HIM, Arora K, Bairy I, Tiwari M, Varadaraj BG, Shenoy GG. | Drug Dev Res | 10.1002/ddr.21623 | 2020 | |
| Pathogenicity | Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating Mycobacterium tuberculosis. | Lopez Quezada L, Li K, McDonald SL, Nguyen Q, Perkowski AJ, Pharr CW, Gold B, Roberts J, McAulay K, Saito K, Somersan Karakaya S, Javidnia PE, Porras de Francisco E, Amieva MM, Di Az SP, Mendoza Losana A, Zimmerman M, Liang HH, Zhang J, Dartois V, Sans S, Lagrange S, Goullieux L, Roubert C, Nathan C, Aube J. | ACS Infect Dis | 10.1021/acsinfecdis.9b00112 | 2019 | |
| Genetics | Prevalence of nontuberculous mycobacteria among extrapulmonary tuberculosis cases in tertiary care centers in Northern India. | Maurya AK, Nag VL, Kant S, Kushwaha RA, Kumar M, Singh AK, Dhole TN. | Biomed Res Int | 10.1155/2015/465403 | 2015 | |
| Pathogenicity | d-Cycloserine Pharmacokinetics/Pharmacodynamics, Susceptibility, and Dosing Implications in Multidrug-resistant Tuberculosis: A Faustian Deal. | Deshpande D, Alffenaar JC, Koser CU, Dheda K, Chapagain ML, Simbar N, Schon T, Sturkenboom MGG, McIlleron H, Lee PS, Koeuth T, Mpagama SG, Banu S, Foongladda S, Ogarkov O, Pholwat S, Houpt ER, Heysell SK, Gumbo T. | Clin Infect Dis | 10.1093/cid/ciy624 | 2018 | |
| Development of New Antimycobacterial Sulfonyl Hydrazones and 4-Methyl-1,2,3-thiadiazole-Based Hydrazone Derivatives. | Angelova VT, Pencheva T, Vassilev N, K-Yovkova E, Mihaylova R, Petrov B, Valcheva V. | Antibiotics (Basel) | 10.3390/antibiotics11050562 | 2022 | | |
| Allium sativum Constituents Exhibit Anti-tubercular Activity In vitro and in RAW 264.7 Mouse Macrophage Cells Infected with Mycobacterium tuberculosis H37Rv. | Nair SS, Gaikwad SS, Kulkarni SP, Mukne AP. | Pharmacogn Mag | 10.4103/pm.pm_435_16 | 2017 | | |
| Lnc-EST12, which is negatively regulated by mycobacterial EST12, suppresses antimycobacterial innate immunity through its interaction with FUBP3. | Yao Q, Xie Y, Xu D, Qu Z, Wu J, Zhou Y, Wei Y, Xiong H, Zhang XL. | Cell Mol Immunol | 10.1038/s41423-022-00878-x | 2022 | | |
| Phenolic Compounds as Promising Drug Candidates in Tuberculosis Therapy. | Mazlun MH, Sabran SF, Mohamed M, Abu Bakar MF, Abdullah Z. | Molecules | 10.3390/molecules24132449 | 2019 | | |
| Multiple PCR assay based on the cigR gene for detection of Salmonella spp. and Salmonella Pullorum/Gallinarum identification. | Zhou YY, Kang XL, Meng C, Xiong D, Xu Y, Geng SZ, Pan ZM, Jiao XA. | Poult Sci | 10.1016/j.psj.2020.07.026 | 2020 | | |
| Enzymology | Accurate and effective multidrug-resistant Mycobacterium tuberculosis detection method using gap-filling ligation coupled with high-resolution capillary electrophoresis-based single strand conformation polymorphism. | Choi W, Lee J, Cho E, Jung GY. | Sci Rep | 10.1038/srep46090 | 2017 | |
| Metabolism | Inhibition of CorA-Dependent Magnesium Homeostasis Is Cidal in Mycobacterium tuberculosis. | Park Y, Ahn YM, Jonnala S, Oh S, Fisher JM, Goodwin MB, Ioerger TR, Via LE, Bayliss T, Green SR, Ray PC, Wyatt PG, Barry CE, Boshoff HI. | Antimicrob Agents Chemother | 10.1128/aac.01006-19 | 2019 | |
| Design of peptides interfering with iron-dependent regulator (IdeR) and evaluation of Mycobacterium tuberculosis growth inhibition. | Salimizand H, Jamehdar SA, Nik LB, Sadeghian H. | Iran J Basic Med Sci | 10.22038/ijbms.2017.8859 | 2017 | | |
| Field Trial with Vaccine Candidates Against Bovine Tuberculosis Among Likely Infected Cattle in a Natural Transmission Setting. | Ferrara Muniz X, Garcia E, Blanco FC, Garbaccio S, Garro C, Zumarraga M, Dellagostin O, Trangoni M, Marfil MJ, Bianco MV, Abdala A, Revelli J, Bergamasco M, Soutullo A, Marini R, Rocha RV, Sanchez A, Bigi F, Canal AM, Eirin ME, Cataldi AA. | Vaccines (Basel) | 10.3390/vaccines12101173 | 2024 | | |
| Pathogenicity | Identifying Regimens Containing TBI-166, a New Drug Candidate against Mycobacterium tuberculosis In Vitro and In Vivo. | Zhang Y, Zhu H, Fu L, Wang B, Guo S, Chen X, Liu Z, Huang H, Yang T, Lu Y. | Antimicrob Agents Chemother | 10.1128/aac.02496-18 | 2019 | |
| Pathogenicity | In Vitro Activity of PBTZ169 against Multiple Mycobacterium Species. | Shi J, Lu J, Wen S, Zong Z, Huo F, Luo J, Liang Q, Li Y, Huang H, Pang Y. | Antimicrob Agents Chemother | 10.1128/aac.01314-18 | 2018 | |
| Metabolism | Compromised Metabolic Reprogramming Is an Early Indicator of CD8+ T Cell Dysfunction during Chronic Mycobacterium tuberculosis Infection. | Russell SL, Lamprecht DA, Mandizvo T, Jones TT, Naidoo V, Addicott KW, Moodley C, Ngcobo B, Crossman DK, Wells G, Steyn AJC. | Cell Rep | 10.1016/j.celrep.2019.11.034 | 2019 | |
| Pathogenicity | Synthesis and antituberculosis activity of some N-pyridyl-N'-thiazolylhydrazine derivatives. | Turan-Zitouni G, Kaplancikli ZA, Ozdemir A. | Eur J Med Chem | 10.1016/j.ejmech.2010.01.017 | 2010 | |
| Pathogenicity | Activity of beta-lapachone derivatives against rifampicin-susceptible and -resistant strains of Mycobacterium tuberculosis. | Coelho TS, Silva RS, Pinto AV, Pinto MC, Scaini CJ, Moura KC, Almeida da Silva P. | Tuberculosis (Edinb) | 10.1016/j.tube.2010.06.001 | 2010 | |
| Pathogenicity | Synthesis and antimycobacterial evaluation of N'-(E)-heteroaromaticpyrazine-2-carbohydrazide derivatives. | Lima CH, Henriques MG, Candea AL, Lourenco MC, Bezerra FA, Ferreira ML, Kaiser CR, de Souza MV. | Med Chem | 10.2174/157340611795564303 | 2011 | |
| In vitro synergistic activity between 8-methoxypsoralen and ethambutol, isoniazid, and rifampin when used in combination against Mycobacterium tuberculosis | Ge F, Zeng F, Guo N, Fan J, Song Y, Liu S, Wu X, Wang X, Deng X, Jin Q, Yu L. | World J Microbiol Biotechnol | 10.1007/s11274-009-0214-0 | 2010 | | |
| Enzymology | In Vitro Antimycobacterial Activity and Physicochemical Characterization of Diaryl Ether Triclosan Analogues as Potential InhA Reductase Inhibitors. | Ibrahim TS, Taher ES, Samir E, M Malebari A, Khayyat AN, Mohamed MFA, Bokhtia RM, AlAwadh MA, Seliem IA, Asfour HZ, Alhakamy NA, Panda SS, Al-Mahmoudy AMM. | Molecules | 10.3390/molecules25143125 | 2020 | |
| Strains of Mycobacterium tuberculosis differ in affinity for human osteoblasts and alveolar cells in vitro. | Sarkar S, Dlamini MG, Bhattacharya D, Ashiru OT, Sturm AW, Moodley P. | Springerplus | 10.1186/s40064-016-1819-z | 2016 | | |
| Metabolism | Bioenergetic Heterogeneity in Mycobacterium tuberculosis Residing in Different Subcellular Niches. | Akela AK, Kumar A. | mBio | 10.1128/mbio.01088-21 | 2021 | |
| Metabolism | CitE Enzymes Are Essential for Mycobacterium tuberculosis to Establish Infection in Macrophages and Guinea Pigs. | Arora G, Chaudhary D, Kidwai S, Sharma D, Singh R. | Front Cell Infect Microbiol | 10.3389/fcimb.2018.00385 | 2018 | |
| Metabolism | A Lysine Acetyltransferase Contributes to the Metabolic Adaptation to Hypoxia in Mycobacterium tuberculosis. | Rittershaus ESC, Baek SH, Krieger IV, Nelson SJ, Cheng YS, Nambi S, Baker RE, Leszyk JD, Shaffer SA, Sacchettini JC, Sassetti CM. | Cell Chem Biol | 10.1016/j.chembiol.2018.09.009 | 2018 | |
| Synthesis and Biological Activities of Camphor Hydrazone and Imine Derivatives. | da Silva ET, da Silva Araujo A, Moraes AM, de Souza LA, Silva Lourenco MC, de Souza MV, Wardell JL, Wardell SM. | Sci Pharm | 10.3390/scipharm84030467 | 2015 | | |
| The Antimicrobial Properties of Cannabis and Cannabis-Derived Compounds and Relevance to CB2-Targeted Neurodegenerative Therapeutics. | Hong H, Sloan L, Saxena D, Scott DA. | Biomedicines | 10.3390/biomedicines10081959 | 2022 | | |
| Metabolism | EBP50 induces apoptosis in macrophages by upregulating nitric oxide production to eliminate intracellular Mycobacterium tuberculosis. | Guo Y, Deng Y, Huang Z, Luo Q, Peng Y, Chen J, Jiang H, Ye J, Li J. | Sci Rep | 10.1038/srep18961 | 2016 | |
| Pathogenicity | Rifabutin and rifampin resistance levels and associated rpoB mutations in clinical isolates of Mycobacterium tuberculosis complex. | Berrada ZL, Lin SY, Rodwell TC, Nguyen D, Schecter GF, Pham L, Janda JM, Elmaraachli W, Catanzaro A, Desmond E. | Diagn Microbiol Infect Dis | 10.1016/j.diagmicrobio.2016.01.019 | 2016 | |
| Pathogenicity | Influence of vehicles used for oral dosing of test molecules on the progression of Mycobacterium tuberculosis infection in mice. | Singh S, Dwivedi R, Chaturvedi V. | Antimicrob Agents Chemother | 10.1128/aac.01702-12 | 2012 | |
| New 1,3-oxazolo[4,5-c]quinoline derivatives: synthesis and evaluation of antibacterial and antituberculosis properties. | Eswaran S, Adhikari AV, Ajay Kumar R. | Eur J Med Chem | 10.1016/j.ejmech.2009.11.036 | 2010 | | |
| Genetics | Frequency of multi-drug resistance and mutations in Mycobacterium tuberculosis isolates from Punjab state of India. | Singhal R, Arora J, Sah GC, Bhalla M, Sarin R, Prasad Myneedu V. | J Epidemiol Glob Health | 10.1016/j.jegh.2017.05.002 | 2017 | |
| Phylogeny | Variation among genome sequences of H37Rv strains of Mycobacterium tuberculosis from multiple laboratories. | Ioerger TR, Feng Y, Ganesula K, Chen X, Dobos KM, Fortune S, Jacobs WR, Mizrahi V, Parish T, Rubin E, Sassetti C, Sacchettini JC. | J Bacteriol | 10.1128/jb.00166-10 | 2010 | |
| Genetics | Comparative Whole-Genomic Analysis of an Ancient L2 Lineage Mycobacterium tuberculosis Reveals a Novel Phylogenetic Clade and Common Genetic Determinants of Hypervirulent Strains. | Rajwani R, Yam WC, Zhang Y, Kang Y, Wong BKC, Leung KSS, Tam KKG, Tulu KT, Zhu L, Siu GKH. | Front Cell Infect Microbiol | 10.3389/fcimb.2017.00539 | 2017 | |
| Pathogenicity | In vitro synergistic interactions of oleanolic acid in combination with isoniazid, rifampicin or ethambutol against Mycobacterium tuberculosis. | Ge F, Zeng F, Liu S, Guo N, Ye H, Song Y, Fan J, Wu X, Wang X, Deng X, Jin Q, Yu L. | J Med Microbiol | 10.1099/jmm.0.014837-0 | 2010 | |
| Pathogenicity | In vitro antimicrobial activities of animal-used quinoxaline 1,4-di-N-oxides against mycobacteria, mycoplasma and fungi. | Zhao Y, Cheng G, Hao H, Pan Y, Liu Z, Dai M, Yuan Z. | BMC Vet Res | 10.1186/s12917-016-0812-7 | 2016 | |
| In vivo evolution of drug-resistant Mycobacterium tuberculosis in patients during long-term treatment. | Xu Y, Liu F, Chen S, Wu J, Hu Y, Zhu B, Sun Z. | BMC Genomics | 10.1186/s12864-018-5010-5 | 2018 | | |
| Elucidating the Antimycobacterial Mechanism of Action of Ciprofloxacin Using Metabolomics. | Knoll KE, Lindeque Z, Adeniji AA, Oosthuizen CB, Lall N, Loots DT. | Microorganisms | 10.3390/microorganisms9061158 | 2021 | | |
| Validation of Cycloserine Efficacy in Treatment of Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis in Beijing, China. | Yu X, Zeng X, Shi W, Hu Y, Nie W, Chu N, Huang H. | Antimicrob Agents Chemother | 10.1128/aac.01824-17 | 2018 | | |
| Viability of stressed Mycobacterium tuberculosis and association with multidrug resistance. | Martins MC, Giampaglia CM, Chimara E, Oliveira RS, Vedovello D, Sakamoto SM, Ferrazoli L. | Braz J Microbiol | 10.1590/s1517-83822013000200019 | 2013 | | |
| Synthesis and antimicrobial activity evaluation of new 1,2,4-triazoles and 1,3,4-thiadiazoles bearing imidazo[2,1-b]thiazole moiety. | Guzeldemirci NU, Kucukbasmaci O. | Eur J Med Chem | 10.1016/j.ejmech.2009.09.024 | 2010 | | |
| Mycobacterial resistance to zinc poisoning requires assembly of P-ATPase-containing membrane metal efflux platforms. | Boudehen YM, Faucher M, Marechal X, Miras R, Rech J, Rombouts Y, Seneque O, Wallat M, Demange P, Bouet JY, Saurel O, Catty P, Gutierrez C, Neyrolles O. | Nat Commun | 10.1038/s41467-022-32085-7 | 2022 | | |
| Viral coinfection promotes tuberculosis immunopathogenesis by type I IFN signaling-dependent impediment of Th1 cell pulmonary influx. | Kang TG, Kwon KW, Kim K, Lee I, Kim MJ, Ha SJ, Shin SJ. | Nat Commun | 10.1038/s41467-022-30914-3 | 2022 | | |
| Isoniazid and rifampin drug susceptibility testing: application of 2,3,5-triphenyl tetrazolium chloride assay and microscopic-observation drug-susceptibility assay directly on Ziehl-Neelsen smear positive sputum specimens. | Shinu P, Singh V, Nair A. | Braz J Infect Dis | 10.1016/j.bjid.2015.09.006 | 2016 | | |
| Pathogenicity | Synthesis of alpha- and beta-pyran naphthoquinones as a new class of antitubercular agents. | Ferreira SB, de Carvalho da Silva F, Bezerra FA, Lourenco MC, Kaiser CR, Pinto AC, Ferreira VF. | Arch Pharm (Weinheim) | 10.1002/ardp.200900162 | 2010 | |
| Parenteral Vaccination With a Tuberculosis Subunit Vaccine in Presence of Retinoic Acid Provides Early but Transient Protection to M. Tuberculosis Infection. | Riccomi A, Piccaro G, Christensen D, Palma C, Andersen P, Vendetti S. | Front Immunol | 10.3389/fimmu.2019.00934 | 2019 | | |
| Pathogenicity | Wild-Type and Non-Wild-Type Mycobacterium tuberculosis MIC Distributions for the Novel Fluoroquinolone Antofloxacin Compared with Those for Ofloxacin, Levofloxacin, and Moxifloxacin. | Yu X, Wang G, Chen S, Wei G, Shang Y, Dong L, Schon T, Moradigaravand D, Parkhill J, Peacock SJ, Koser CU, Huang H. | Antimicrob Agents Chemother | 10.1128/aac.00393-16 | 2016 | |
| Pathogenicity | A novel resistance mutation in eccC5 of the ESX-5 secretion system confers ofloxacin resistance in Mycobacterium tuberculosis. | Eilertson B, Maruri F, Blackman A, Guo Y, Herrera M, van der Heijden Y, Shyr Y, Sterling TR. | J Antimicrob Chemother | 10.1093/jac/dkw168 | 2016 | |
| Pharmacological Activities of Zingiber officinale Roscoe: Inhibition of HSA Protein Glycation, Structure Stability and Function Restoration. | Khan MWA, Sherwani S, Alshammari MHE, Alsukaibi AKD, Khan WA, Haque A, Alenezi KM, Shahab U. | Pharmaceuticals (Basel) | 10.3390/ph17111469 | 2024 | | |
| Pathogenicity | 2(3H)-furanones and 2(3H)-pyrrolones: synthesis and antimycobacterial evaluation. | Husain A, Alam MM, Hasan SM, Yar MS. | Acta Pol Pharm | 2009 | | |
| Design and synthesis of novel quinoxaline derivatives as potential candidates for treatment of multidrug-resistant and latent tuberculosis. | Santivanez-Veliz M, Perez-Silanes S, Torres E, Moreno-Viguri E. | Bioorg Med Chem Lett | 10.1016/j.bmcl.2016.03.066 | 2016 | | |
| Metabolism | Biofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis. | Chakraborty P, Bajeli S, Kaushal D, Radotra BD, Kumar A. | Nat Commun | 10.1038/s41467-021-21748-6 | 2021 | |
| Structure based design of effective HtpG-derived vaccine antigens against M. tuberculosis. | Ruggiero A, Choi HG, Barra G, Squeglia F, Back YW, Kim HJ, Berisio R. | Front Mol Biosci | 10.3389/fmolb.2022.964645 | 2022 | | |
| Pathogenicity | Evaluation of BACTEC MGIT 960 system for testing susceptibility of Mycobacterium tuberculosis to first-line drugs in China. | Zhao P, Fang F, Yu Q, Guo J, Zhang JH, Qu J, Liu Y. | PLoS One | 10.1371/journal.pone.0099659 | 2014 | |
| Association between embB Codon 306 Mutations, Phenotypic Resistance Profiles, and Genotypic Characterization in Clinical Mycobacterium tuberculosis Isolates from Hebei, China. | Li Y, Wang Y, Zhang Z, Gao H, Wang H, Cao J, Zhang S, Liu Y, Lu J, Xu Z, Dai E. | Antimicrob Agents Chemother | 10.1128/aac.00532-16 | 2016 | | |
| Metabolism | Two Faces of CwlM, an Essential PknB Substrate, in Mycobacterium tuberculosis. | Turapov O, Forti F, Kadhim B, Ghisotti D, Sassine J, Straatman-Iwanowska A, Bottrill AR, Moynihan PJ, Wallis R, Barthe P, Cohen-Gonsaud M, Ajuh P, Vollmer W, Mukamolova GV. | Cell Rep | 10.1016/j.celrep.2018.09.004 | 2018 | |
| Pathogenicity | Isoniazid induces apoptosis of activated CD4+ T cells: implications for post-therapy tuberculosis reactivation and reinfection. | Tousif S, Singh DK, Ahmad S, Moodley P, Bhattacharyya M, Van Kaer L, Das G. | J Biol Chem | 10.1074/jbc.c114.598946 | 2014 | |
| Metabolism | Role of the Cys154Arg Substitution in Ribosomal Protein L3 in Oxazolidinone Resistance in Mycobacterium tuberculosis. | Makafe GG, Cao Y, Tan Y, Julius M, Liu Z, Wang C, Njire MM, Cai X, Liu T, Wang B, Pang W, Tan S, Zhang B, Yew WW, Lamichhane G, Guo J, Zhang T. | Antimicrob Agents Chemother | 10.1128/aac.00152-16 | 2016 | |
| Enzymology | Early Bactericidal Activity Trial of Nitazoxanide for Pulmonary Tuberculosis. | Walsh KF, McAulay K, Lee MH, Vilbrun SC, Mathurin L, Jean Francois D, Zimmerman M, Kaya F, Zhang N, Saito K, Ocheretina O, Savic R, Dartois V, Johnson WD, Pape JW, Nathan C, Fitzgerald DW. | Antimicrob Agents Chemother | 10.1128/aac.01956-19 | 2020 | |
| Antimicrobial Peptide against Mycobacterium Tuberculosis That Activates Autophagy Is an Effective Treatment for Tuberculosis. | Pelaez Coyotl EA, Barrios Palacios J, Mucino G, Moreno-Blas D, Costas M, Montiel Montes T, Diener C, Uribe-Carvajal S, Massieu L, Castro-Obregon S, Espinosa OR, Mata Espinosa D, Barrios-Payan J, Leon Contreras JC, Corzo G, Hernandez-Pando R, Del Rio G. | Pharmaceutics | 10.3390/pharmaceutics12111071 | 2020 | | |
| Genetics | Role of GenoType(®) Mycobacterium Common Mycobacteria/Additional Species Assay for Rapid Differentiation Between Mycobacterium tuberculosis Complex and Different Species of Non-Tuberculous Mycobacteria. | Singh AK, Maurya AK, Umrao J, Kant S, Kushwaha RA, Nag VL, Dhole TN. | J Lab Physicians | 10.4103/0974-2727.119847 | 2013 | |
| Antibacterial constituents of three Cameroonian medicinal plants: Garcinia nobilis, Oricia suaveolens and Balsamocitrus camerunensis. | Fouotsa H, Mbaveng AT, Mbazoa CD, Nkengfack AE, Farzana S, Iqbal CM, Meyer JJ, Lall N, Kuete V. | BMC Complement Altern Med | 10.1186/1472-6882-13-81 | 2013 | | |
| Pathogenicity | Intracellular activity of tedizolid phosphate and ACH-702 versus Mycobacterium tuberculosis infected macrophages. | Molina-Torres CA, Barba-Marines A, Valles-Guerra O, Ocampo-Candiani J, Cavazos-Rocha N, Pucci MJ, Castro-Garza J, Vera-Cabrera L. | Ann Clin Microbiol Antimicrob | 10.1186/1476-0711-13-13 | 2014 | |
| Drug resistance characteristics of Mycobacterium tuberculosis isolates between 2014 and 2017 in Sichuan, China: A retrospective study. | Zhou M, Liu S, Li Q, Wang Q, Zhu M, Cao L, Wang D, Xu Y, Zheng T, Ye Q, Hu X, Zuo H, Pei X. | PLoS One | 10.1371/journal.pone.0209902 | 2018 | | |
| Pathogenicity | Linezolid resistance in patients with drug-resistant TB and treatment failure in South Africa. | Wasserman S, Louw G, Ramangoaela L, Barber G, Hayes C, Omar SV, Maartens G, Barry C, Song T, Meintjes G. | J Antimicrob Chemother | 10.1093/jac/dkz206 | 2019 | |
| High rates of nontuberculous mycobacteria isolation from patients with presumptive tuberculosis in Iran. | Nasiri MJ, Dabiri H, Fooladi AAI, Amini S, Hamzehloo G, Feizabadi MM. | New Microbes New Infect | 10.1016/j.nmni.2017.08.008 | 2018 | | |
| Biological Activities of Bismuth Compounds: An Overview of the New Findings and the Old Challenges Not Yet Overcome. | Rosario JDS, Moreira FH, Rosa LHF, Guerra W, Silva-Caldeira PP. | Molecules | 10.3390/molecules28155921 | 2023 | | |
| Metabolism | Mycobacterium tuberculosis Rv2882c Protein Induces Activation of Macrophages through TLR4 and Exhibits Vaccine Potential. | Choi HG, Choi S, Back YW, Park HS, Bae HS, Choi CH, Kim HJ. | PLoS One | 10.1371/journal.pone.0164458 | 2016 | |
| Pathogenicity | In vitro activity of rifampicin and verapamil combination in multidrug-resistant mycobacterium tuberculosis. | Demitto Fde O, do Amaral RC, Maltempe FG, Siqueira VL, Scodro RB, Lopes MA, Caleffi-Ferracioli KR, Canezin PH, Cardoso RF. | PLoS One | 10.1371/journal.pone.0116545 | 2015 | |
| sncRNA-1 Is a Small Noncoding RNA Produced by Mycobacterium tuberculosis in Infected Cells That Positively Regulates Genes Coupled to Oleic Acid Biosynthesis. | Coskun FS, Srivastava S, Raj P, Dozmorov I, Belkaya S, Mehra S, Golden NA, Bucsan AN, Chapagain ML, Wakeland EK, Kaushal D, Gumbo T, van Oers NSC. | Front Microbiol | 10.3389/fmicb.2020.01631 | 2020 | | |
| Pathogenicity | Genome-Wide Gene Expression Analysis of Mtb-Infected DC Highlights the Rapamycin-Driven Modulation of Regulatory Cytokines via the mTOR/GSK-3beta Axis. | Etna MP, Severa M, Licursi V, Pardini M, Cruciani M, Rizzo F, Giacomini E, Macchia G, Palumbo O, Stallone R, Carella M, Livingstone M, Negri R, Pellegrini S, Coccia EM. | Front Immunol | 10.3389/fimmu.2021.649475 | 2021 | |
| Pathogenicity | Synthesis and antituberculosis activity of new hydrazide derivatives. | Kaplancikli ZA, Turan-Zitouni G, Ozdemir A, Teulade JC. | Arch Pharm (Weinheim) | 10.1002/ardp.200800048 | 2008 | |
| Metabolism | Hydrogen sulfide-induced GAPDH sulfhydration disrupts the CCAR2-SIRT1 interaction to initiate autophagy. | Iqbal IK, Bajeli S, Sahu S, Bhat SA, Kumar A. | Autophagy | 10.1080/15548627.2021.1876342 | 2021 | |
| Pathogenicity | Effect of coadministration of moxifloxacin and rifampin on Mycobacterium tuberculosis in a murine aerosol infection model. | Balasubramanian V, Solapure S, Gaonkar S, Mahesh Kumar KN, Shandil RK, Deshpande A, Kumar N, Vishwas KG, Panduga V, Reddy J, Ganguly S, Louie A, Drusano GL. | Antimicrob Agents Chemother | 10.1128/aac.06383-11 | 2012 | |
| Cumulative Fraction of Response for Once- and Twice-Daily Delamanid in Patients with Pulmonary Multidrug-Resistant Tuberculosis. | Mallikaarjun S, Chapagain ML, Sasaki T, Hariguchi N, Deshpande D, Srivastava S, Berg A, Hirota K, Inoue Y, Matsumoto M, Hafkin J, Geiter L, Wang X, Gumbo T, Liu Y. | Antimicrob Agents Chemother | 10.1128/aac.01207-20 | 2020 | | |
| Metabolism | A Novel In Vitro Mouse Model to Study Mycobacterium tuberculosis Dissemination Across Brain Vessels: A Combination Granuloma and Blood-Brain Barrier Mouse Model. | Walter FR, Gilpin TE, Herbath M, Deli MA, Sandor M, Fabry Z. | Curr Protoc Immunol | 10.1002/cpim.101 | 2020 | |
| Design of novel iron compounds as potential therapeutic agents against tuberculosis. | Tarallo MB, Urquiola C, Monge A, Costa BP, Ribeiro RR, Costa-Filho AJ, Mercader RC, Pavan FR, Leite CQ, Torre MH, Gambino D. | J Inorg Biochem | 10.1016/j.jinorgbio.2010.07.005 | 2010 | | |
| Pathogenicity | IFN-alpha Boosting of Mycobacterium bovis Bacillus Calmette Güerin-Vaccine Promoted Th1 Type Cellular Response and Protection against M. tuberculosis Infection. | Rivas-Santiago CE, Guerrero GG. | Biomed Res Int | 10.1155/2017/8796760 | 2017 | |
| Detection of multi-drug resistance & characterization of mutations in Mycobacterium tuberculosis isolates from North- Eastern States of India using GenoType MTBDRplus assay. | Singhal R, Myneedu VP, Arora J, Singh N, Sah GC, Sarin R. | Indian J Med Res | 2014 | | ||
| Pathogenicity | QSAR modeling of a set of pyrazinoate esters as antituberculosis prodrugs. | Fernandes JP, Pasqualoto KF, Felli VM, Ferreira EI, Brandt CA. | Arch Pharm (Weinheim) | 10.1002/ardp.200900216 | 2010 | |
| Enzymology | Differentially Detectable Mycobacterium tuberculosis Cells in Sputum from Treatment-Naive Subjects in Haiti and Their Proportionate Increase after Initiation of Treatment. | McAulay K, Saito K, Warrier T, Walsh KF, Mathurin LD, Royal-Mardi G, Lee MH, Ocheretina O, Pape JW, Fitzgerald DW, Nathan CF. | mBio | 10.1128/mbio.02192-18 | 2018 | |
| Mycolicibacterium smegmatis, Basonym Mycobacterium smegmatis, Expresses Morphological Phenotypes Much More Similar to Escherichia coli Than Mycobacterium tuberculosis in Quantitative Structome Analysis and CryoTEM Examination. | Yamada H, Yamaguchi M, Igarashi Y, Chikamatsu K, Aono A, Murase Y, Morishige Y, Takaki A, Chibana H, Mitarai S. | Front Microbiol | 10.3389/fmicb.2018.01992 | 2018 | | |
| Metabolism | Coupling of Peptidoglycan Synthesis to Central Metabolism in Mycobacteria: Post-transcriptional Control of CwlM by Aconitase. | Bancroft PJ, Turapov O, Jagatia H, Arnvig KB, Mukamolova GV, Green J. | Cell Rep | 10.1016/j.celrep.2020.108209 | 2020 | |
| Anti-Mycobacterium tuberculosis activity of fungus Phomopsis stipata. | de Prince KA, Sordi R, Pavan FR, Barreto Santos AC, Araujo AR, Leite SR, Leite CQ. | Braz J Microbiol | 10.1590/s1517-838220120001000024 | 2012 | | |
| Pathogenicity | Tissue Distribution of Doxycycline in Animal Models of Tuberculosis. | Gengenbacher M, Zimmerman MD, Sarathy JP, Kaya F, Wang H, Mina M, Carter C, Hossen MA, Su H, Trujillo C, Ehrt S, Schnappinger D, Dartois V. | Antimicrob Agents Chemother | 10.1128/aac.02479-19 | 2020 | |
| Pathogenicity | Prevalence and extent of heteroresistance by next generation sequencing of multidrug-resistant tuberculosis. | Operario DJ, Koeppel AF, Turner SD, Bao Y, Pholwat S, Banu S, Foongladda S, Mpagama S, Gratz J, Ogarkov O, Zhadova S, Heysell SK, Houpt ER. | PLoS One | 10.1371/journal.pone.0176522 | 2017 | |
| Pathogenicity | Mycobacterium tuberculosis Proteome Response to Antituberculosis Compounds Reveals Metabolic "Escape" Pathways That Prolong Bacterial Survival. | Danelishvili L, Shulzhenko N, Chinison JJJ, Babrak L, Hu J, Morgun A, Burrows G, Bermudez LE. | Antimicrob Agents Chemother | 10.1128/aac.00430-17 | 2017 | |
| Pathogenicity | Synthesis and antimycobacterial activity of N'-[(E)-(monosubstituted-benzylidene)]-2-pyrazinecarbohydrazide derivatives. | Vergara FM, Lima CH, Henriques Md, Candea AL, Lourenco MC, Ferreira Mde L, Kaiser CR, de Souza MV. | Eur J Med Chem | 10.1016/j.ejmech.2009.08.009 | 2009 | |
| Design, synthesis and in vitro evaluation of antitubercular and antimicrobial activity of some novel pyranopyrimidines. | Kamdar NR, Haveliwala DD, Mistry PT, Patel SK. | Eur J Med Chem | 10.1016/j.ejmech.2010.08.014 | 2010 | | |
| Pathogenicity | Reduced susceptibility of clinical strains of Mycobacterium tuberculosis to reactive nitrogen species promotes survival in activated macrophages. | Idh J, Andersson B, Lerm M, Raffetseder J, Eklund D, Woksepp H, Werngren J, Mansjo M, Sundqvist T, Stendahl O, Schon T. | PLoS One | 10.1371/journal.pone.0181221 | 2017 | |
| Pathogenicity | Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase. | Santa Maria JP, Park Y, Yang L, Murgolo N, Altman MD, Zuck P, Adam G, Chamberlin C, Saradjian P, Dandliker P, Boshoff HIM, Barry CE, Garlisi C, Olsen DB, Young K, Glick M, Nickbarg E, Kutchukian PS. | ACS Chem Biol | 10.1021/acschembio.7b00468 | 2017 | |
| Pathogenicity | Plants in our combating strategies against Mycobacterium tuberculosis: progress made and obstacles met. | Gupta VK, Kumar MM, Bisht D, Kaushik A. | Pharm Biol | 10.1080/13880209.2017.1309440 | 2017 | |
| Systematic Evolution of Ligands by Exponential Enrichment Technologies and Aptamer-Based Applications: Recent Progress and Challenges in Precision Medicine of Infectious Diseases. | Xu Y, Jiang X, Zhou Y, Ma M, Wang M, Ying B. | Front Bioeng Biotechnol | 10.3389/fbioe.2021.704077 | 2021 | | |
| Enzymology | Population Pharmacokinetics of Levofloxacin and Moxifloxacin, and the Probability of Target Attainment in Ethiopian Patients with Multidrug-Resistant Tuberculosis. | Sidamo T, Rao PS, Aklillu E, Shibeshi W, Park Y, Cho YS, Shin JG, Heysell SK, Mpagama SG, Engidawork E. | Infect Drug Resist | 10.2147/idr.s389442 | 2022 | |
| Evaluation of phytochemical composition, toxicity in Drosophila melanogaster and effects on antibiotics modulation of Plathymenia reticulata Benth extract. | Luna EM, Freitas TS, Campina FF, Costa MS, Rocha JE, Cruz RP, Sena Junior DL, Silveira ZS, Macedo NS, Pinheiro JCA, Pereira-Junior FN, Lisboa MAN, Cruz GV, Calixto Junior JT, Teixeira AMR, Coutinho HDM. | Toxicol Rep | 10.1016/j.toxrep.2021.03.020 | 2021 | | |
| Genetics | Endogenous relapse and exogenous reinfection in recurrent pulmonary tuberculosis: A retrospective study revealed by whole genome sequencing. | He W, Tan Y, Song Z, Liu B, Wang Y, He P, Xia H, Huang F, Liu C, Zheng H, Pei S, Liu D, Ma A, Cao X, Zhao B, Ou X, Wang S, Zhao Y. | Front Microbiol | 10.3389/fmicb.2023.1115295 | 2023 | |
| New N-phenylacetamide-incorporated 1,2,3-triazoles: [Et3NH][OAc]-mediated efficient synthesis and biological evaluation. | Akolkar SV, Nagargoje AA, Krishna VS, Sriram D, Sangshetti JN, Damale M, Shingate BB. | RSC Adv | 10.1039/c9ra03425k | 2019 | | |
| Mycobacterium tuberculosis Protein Rv3841 Activates Dendritic Cells and Contributes to a T Helper 1 Immune Response. | Choi S, Choi HG, Shin KW, Back YW, Park HS, Lee JH, Kim HJ. | J Immunol Res | 10.1155/2018/3525302 | 2018 | | |
| Epidemiological cut-off values for a 96-well broth microdilution plate for high-throughput research antibiotic susceptibility testing of M. tuberculosis. | CRyPTIC Consortium. | Eur Respir J | 10.1183/13993003.00239-2022 | 2022 | | |
| Pathogenicity | PLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infection. | Ashhurst AS, Parumasivam T, Chan JGY, Lin LCW, Florido M, West NP, Chan HK, Britton WJ. | PLoS One | 10.1371/journal.pone.0194620 | 2018 | |
| Antimicrobial and cytotoxicity properties of the organic solvent fractions of Clerodendrum myricoides (Hochst.) R. Br. ex Vatke: Kenyan traditional medicinal plant. | Njeru SN, Obonyo M, Nyambati S, Ngari S, Mwakubambanya R, Mavura H. | J Intercult Ethnopharmacol | 10.5455/jice.20160416122003 | 2016 | | |
| The anti-tubercular activity of Melia azedarach L. and Lobelia chinensis Lour. and their potential as effective anti-Mycobacterium tuberculosis candidate agents. | Choi WH, Lee IA. | Asian Pac J Trop Biomed | 10.1016/j.apjtb.2016.08.007 | 2016 | | |
| Therapeutic Outcomes of Isatin and Its Derivatives against Multiple Diseases: Recent Developments in Drug Discovery. | Cheke RS, Patil VM, Firke SD, Ambhore JP, Ansari IA, Patel HM, Shinde SD, Pasupuleti VR, Hassan MI, Adnan M, Kadri A, Snoussi M. | Pharmaceuticals (Basel) | 10.3390/ph15030272 | 2022 | | |
| Pathogenicity | Evaluation of pseudopteroxazole and pseudopterosin derivatives against Mycobacterium tuberculosis and other pathogens. | McCulloch MWB, Haltli B, Marchbank DH, Kerr RG. | Mar Drugs | 10.3390/md10081711 | 2012 | |
| Enzymology | 1-(1-Arylethylpiperidin-4-yl)thymine Analogs as Antimycobacterial TMPK Inhibitors. | Jian Y, Hulpia F, D P Risseeuw M, Forbes HE, Caljon G, Munier-Lehmann H, I M Boshoff H, Van Calenbergh S. | Molecules | 10.3390/molecules25122805 | 2020 | |
| Transcriptome | The Diversified O-Superfamily in Californiconus californicus Presents a Conotoxin with Antimycobacterial Activity. | Bernaldez-Sarabia J, Figueroa-Montiel A, Duenas S, Cervantes-Luevano K, Beltran JA, Ortiz E, Jimenez S, Possani LD, Paniagua-Solis JF, Gonzalez-Canudas J, Licea-Navarro A. | Toxins (Basel) | 10.3390/toxins11020128 | 2019 | |
| Pathogenicity | The potential use of rifabutin for treatment of patients diagnosed with rifampicin-resistant tuberculosis. | Whitfield MG, Warren RM, Mathys V, Scott L, De Vos E, Stevens W, Stevens W, Streicher EM, Groenen G, Sirgel FA, Van Rie A. | J Antimicrob Chemother | 10.1093/jac/dky248 | 2018 | |
| Pathogenicity | Comparative Genomic Analysis of Two Clonally Related Multidrug Resistant Mycobacterium tuberculosis by Single Molecule Real Time Sequencing. | Leung KS, Siu GK, Tam KK, To SW, Rajwani R, Ho PL, Wong SS, Zhao WW, Ma OC, Yam WC. | Front Cell Infect Microbiol | 10.3389/fcimb.2017.00478 | 2017 | |
| A Clofazimine-Containing Regimen Confers Improved Treatment Outcomes in Macrophages and in a Murine Model of Chronic Progressive Pulmonary Infection Caused by the Mycobacterium avium Complex. | Lee JM, Park J, Choi S, Jhun BW, Kim SY, Jo KW, Hong JJ, Kim LH, Shin SJ. | Front Microbiol | 10.3389/fmicb.2020.626216 | 2020 | | |
| Pathogenicity | Antimycobacterial activity of natural and semi-synthetic lignans. | Silva ML, Martins CH, Lucarini R, Sato DN, Pavanb FR, Freitas NH, Andrade LN, Pereira AC, Bianco TN, Vinholis AH, Cunha WR, Bastos JK, Silva R, Da Silva Filho AA. | Z Naturforsch C J Biosci | 10.1515/znc-2009-11-1204 | 2009 | |
| Pathogenicity | Rufomycin Targets ClpC1 Proteolysis in Mycobacterium tuberculosis and M. abscessus. | Choules MP, Wolf NM, Lee H, Anderson JR, Grzelak EM, Wang Y, Ma R, Gao W, McAlpine JB, Jin YY, Cheng J, Lee H, Suh JW, Duc NM, Paik S, Choe JH, Jo EK, Chang CL, Lee JS, Jaki BU, Pauli GF, Franzblau SG, Cho S. | Antimicrob Agents Chemother | 10.1128/aac.02204-18 | 2019 | |
| Pathogenicity | Antibacterial activity of ergosterol peroxide against Mycobacterium tuberculosis: dependence upon system and medium employed. | Duarte N, Ferreira MJ, Martins M, Viveiros M, Amaral L. | Phytother Res | 10.1002/ptr.2119 | 2007 | |
| Pathogenicity | In Vitro Activities of Bedaquiline and Delamanid against Nontuberculous Mycobacteria Isolated in Beijing, China. | Yu X, Gao X, Li C, Luo J, Wen S, Zhang T, Ma Y, Dong L, Wang F, Huang H. | Antimicrob Agents Chemother | 10.1128/aac.00031-19 | 2019 | |
| Pathogenicity | Preliminary antimycobacterial study on selected Turkish plants (Lamiaceae) against Mycobacterium tuberculosis and search for some phenolic constituents. | Askun T, Tekwu EM, Satil F, Modanlioglu S, Aydeniz H. | BMC Complement Altern Med | 10.1186/1472-6882-13-365 | 2013 | |
| Association of Mycobacterium Proteins with Lipid Droplets. | Armstrong RM, Carter DC, Atkinson SN, Terhune SS, Zahrt TC. | J Bacteriol | 10.1128/jb.00240-18 | 2018 | | |
| Metabolism | TGFbeta restricts expansion, survival, and function of T cells within the tuberculous granuloma. | Gern BH, Adams KN, Plumlee CR, Stoltzfus CR, Shehata L, Moguche AO, Busman-Sahay K, Hansen SG, Axthelm MK, Picker LJ, Estes JD, Urdahl KB, Gerner MY. | Cell Host Microbe | 10.1016/j.chom.2021.02.005 | 2021 | |
| Discovery of quinolone derivatives as antimycobacterial agents. | Liu KL, Teng F, Xiong L, Li X, Gao C, Yu LT. | RSC Adv | 10.1039/d0ra09250a | 2021 | | |
| Pathogenicity | Characterization of antibacterial and hemolytic activity of synthetic pandinin 2 variants and their inhibition against Mycobacterium tuberculosis. | Rodriguez A, Villegas E, Montoya-Rosales A, Rivas-Santiago B, Corzo G. | PLoS One | 10.1371/journal.pone.0101742 | 2014 | |
| Phosphorus-nitrogen compounds. 18. Syntheses, stereogenic properties, structural and electrochemical investigations, biological activities, and DNA interactions of new spirocyclic mono- and bisferrocenylphosphazene derivatives. | Asmafiliz N, Kilic Z, Ozturk A, Hokelek T, Koc LY, Acik L, Kisa O, Albay A, Ustundag Z, Solak AO. | Inorg Chem | 10.1021/ic901039k | 2009 | | |
| Humanized Mouse Model Mimicking Pathology of Human Tuberculosis for in vivo Evaluation of Drug Regimens. | Arrey F, Lowe D, Kuhlmann S, Kaiser P, Moura-Alves P, Krishnamoorthy G, Lozza L, Maertzdorf J, Skrahina T, Skrahina A, Gengenbacher M, Nouailles G, Kaufmann SHE. | Front Immunol | 10.3389/fimmu.2019.00089 | 2019 | | |
| Phytochemical screening of five medicinal legumes and their evaluation for in vitro anti-tubercular activity. | Kumar JK, Devi Prasad AG, Chaturvedi V. | Ayu | 10.4103/0974-8520.141952 | 2014 | | |
| A nucleotidyltransferase toxin inhibits growth of Mycobacterium tuberculosis through inactivation of tRNA acceptor stems. | Cai Y, Usher B, Gutierrez C, Tolcan A, Mansour M, Fineran PC, Condon C, Neyrolles O, Genevaux P, Blower TR. | Sci Adv | 10.1126/sciadv.abb6651 | 2020 | | |
| Metabolism | Synthesis of some 4-arylidenamino-4H-1,2,4-triazole-3-thiols and their antituberculosis activity. | Ozdemir A, Turan-Zitouni G, Kaplancikli ZA, Chevallet P. | J Enzyme Inhib Med Chem | 10.1080/14756360601178424 | 2007 | |
| Metabolism | Mesenchymal stem cells internalize Mycobacterium tuberculosis through scavenger receptors and restrict bacterial growth through autophagy. | Khan A, Mann L, Papanna R, Lyu MA, Singh CR, Olson S, Eissa NT, Cirillo J, Das G, Hunter RL, Jagannath C. | Sci Rep | 10.1038/s41598-017-15290-z | 2017 | |
| Pathogenicity | In vitro and in vivo activities of ruthenium(II) phosphine/diimine/picolinate complexes (SCAR) against Mycobacterium tuberculosis. | Pavan FR, Poelhsitz GV, da Cunha LV, Barbosa MI, Leite SR, Batista AA, Cho SH, Franzblau SG, de Camargo MS, Resende FA, Varanda EA, Leite CQ. | PLoS One | 10.1371/journal.pone.0064242 | 2013 | |
| Pathogenicity | Genome-wide transcription analyses in Mycobacterium tuberculosis treated with lupulone. | Wei J, Liang J, Shi Q, Yuan P, Meng R, Tang X, Yu L, Guo N. | Braz J Microbiol | 10.1590/s1517-83822014005000032 | 2014 | |
| Metabolism | Anaerobic Mycobacterium tuberculosis Cell Death Stems from Intracellular Acidification Mitigated by the DosR Regulon. | Reichlen MJ, Leistikow RL, Scobey MS, Born SEM, Voskuil MI. | J Bacteriol | 10.1128/jb.00320-17 | 2017 | |
| [Protein profiling of human dendritic cells infected with mycobacterium tuberculosis]. | Bao JL, Le J, Tian YP, Yang YP, Wang HH. | Wei Sheng Wu Xue Bao | 2005 | | ||
| The tuberculocidal activity of polyaniline and functionalised polyanilines. | Robertson J, Dalton J, Wiles S, Gizdavic-Nikolaidis M, Swift S. | PeerJ | 10.7717/peerj.2795 | 2016 | | |
| CXCR6-Deficiency Improves the Control of Pulmonary Mycobacterium tuberculosis and Influenza Infection Independent of T-Lymphocyte Recruitment to the Lungs. | Ashhurst AS, Florido M, Lin LCW, Quan D, Armitage E, Stifter SA, Stambas J, Britton WJ. | Front Immunol | 10.3389/fimmu.2019.00339 | 2019 | | |
| Comparison of single-copy and multicopy real-time PCR targets for detection of Mycobacterium tuberculosis in paraffin-embedded tissue. | Luo RF, Scahill MD, Banaei N. | J Clin Microbiol | 10.1128/jcm.02449-09 | 2010 | | |
| Boromycin Kills Mycobacterial Persisters without Detectable Resistance. | Moreira W, Aziz DB, Dick T. | Front Microbiol | 10.3389/fmicb.2016.00199 | 2016 | | |
| Pathogenicity | Evaluation of Chemical Composition and Antileishmanial and Antituberculosis Activities of Essential Oils of Piper Species. | Bernuci KZ, Iwanaga CC, Fernadez-Andrade CM, Lorenzetti FB, Torres-Santos EC, Faioes VD, Goncalves JE, do Amaral W, Deschamps C, Scodro RB, Cardoso RF, Baldin VP, Cortez DA. | Molecules | 10.3390/molecules21121698 | 2016 | |
| Pathogenicity | Evaluation of Direct Colorimetric MTT Assay for Rapid Detection of Rifampicin and Isoniazid Resistance in Mycobacterium tuberculosis. | Hundie GB, Woldemeskel D, Gessesse A. | PLoS One | 10.1371/journal.pone.0169188 | 2016 | |
| NLRC3 negatively regulates CD4+ T cells and impacts protective immunity during Mycobacterium tuberculosis infection. | Hu S, Du X, Huang Y, Fu Y, Yang Y, Zhan X, He W, Wen Q, Zhou X, Zhou C, Zhong XP, Yang J, Xiong W, Wang R, Gao Y, Ma L. | PLoS Pathog | 10.1371/journal.ppat.1007266 | 2018 | | |
| Phylogeny | Multidrug-Resistant Mycobacterium tuberculosis of the Latin American Mediterranean Lineage, Wrongly Identified as Mycobacterium pinnipedii (Spoligotype International Type 863 [SIT863]), Causing Active Tuberculosis in South Brazil. | Dalla Costa ER, Vasconcelos SE, Esteves LS, Gomes HM, Gomes LL, da Silva PA, Perdigao J, Portugal I, Viveiros M, McNerney R, Pain A, Clark TG, Rastogi N, Unis G, Rossetti ML, Suffys PN. | J Clin Microbiol | 10.1128/jcm.02012-15 | 2015 | |
| Nitric Oxide in the Pathogenesis and Treatment of Tuberculosis. | Jamaati H, Mortaz E, Pajouhi Z, Folkerts G, Movassaghi M, Moloudizargari M, Adcock IM, Garssen J. | Front Microbiol | 10.3389/fmicb.2017.02008 | 2017 | | |
| An attenuated Mycobacterium tuberculosis clinical strain with a defect in ESX-1 secretion induces minimal host immune responses and pathology. | Clemmensen HS, Knudsen NPH, Rasmussen EM, Winkler J, Rosenkrands I, Ahmad A, Lillebaek T, Sherman DR, Andersen PL, Aagaard C. | Sci Rep | 10.1038/srep46666 | 2017 | | |
| A highly effective and inexpensive standardized treatment of multidrug-resistant tuberculosis: a multicenter prospective study in China. | Sun W, Wu Z, Zhou Y, Xia F, Tang Q, Wang J, Yang J, Yu F, Yang H, Xiao H, Fan L. | BMC Infect Dis | 10.1186/s12879-021-06553-2 | 2021 | | |
| Enzymology | Early and efficient detection of Mycobacterium tuberculosis in sputum by microscopic observation of broth cultures. | Kidenya BR, Kabangila R, Peck RN, Mshana SE, Webster LE, Koenig SP, Johnson WD, Fitzgerald DW. | PLoS One | 10.1371/journal.pone.0057527 | 2013 | |
| Pathogenicity | Gut Microbiota Metabolite Indole Propionic Acid Targets Tryptophan Biosynthesis in Mycobacterium tuberculosis. | Negatu DA, Yamada Y, Xi Y, Go ML, Zimmerman M, Ganapathy U, Dartois V, Gengenbacher M, Dick T. | mBio | 10.1128/mbio.02781-18 | 2019 | |
| Association of gyrA/B mutations and resistance levels to fluoroquinolones in clinical isolates of Mycobacterium tuberculosis. | Li J, Gao X, Luo T, Wu J, Sun G, Liu Q, Jiang Y, Zhang Y, Mei J, Gao Q. | Emerg Microbes Infect | 10.1038/emi.2014.21 | 2014 | | |
| Pathogenicity | Verapamil Targets Membrane Energetics in Mycobacterium tuberculosis. | Chen C, Gardete S, Jansen RS, Shetty A, Dick T, Rhee KY, Dartois V. | Antimicrob Agents Chemother | 10.1128/aac.02107-17 | 2018 | |
| Pathogenicity | CHEMICAL CHARACTERIZATION AND EVALUATION OF ANTIBACTERIAL, ANTIFUNGAL, ANTIMYCOBACTERIAL, AND CYTOTOXIC ACTIVITIES OF Talinum paniculatum. | Dos Reis LF, Cerdeira CD, De Paula BF, Silva JJ, Coelho LF, Silva MA, Marques VB, Chavasco JK, Alves-Da-Silva G. | Rev Inst Med Trop Sao Paulo | 10.1590/s0036-46652015000500005 | 2015 | |
| Primary macrophages and J774 cells respond differently to infection with Mycobacterium tuberculosis. | Andreu N, Phelan J, de Sessions PF, Cliff JM, Clark TG, Hibberd ML. | Sci Rep | 10.1038/srep42225 | 2017 | | |
| Metabolism | NOD2/RIG-I Activating Inarigivir Adjuvant Enhances the Efficacy of BCG Vaccine Against Tuberculosis in Mice. | Khan A, Singh VK, Mishra A, Soudani E, Bakhru P, Singh CR, Zhang D, Canaday DH, Sheri A, Padmanabhan S, Challa S, Iyer RP, Jagannath C. | Front Immunol | 10.3389/fimmu.2020.592333 | 2020 | |
| Phylogeny | Novel DNA chip based on a modified DigiTag2 assay for high-throughput species identification and genotyping of Mycobacterium tuberculosis complex isolates. | Srilohasin P, Chaiprasert A, Tokunaga K, Nao N, Prammananan T. | J Clin Microbiol | 10.1128/jcm.00153-14 | 2014 | |
| MmpL3 as a Target for the Treatment of Drug-Resistant Nontuberculous Mycobacterial Infections. | Li W, Yazidi A, Pandya AN, Hegde P, Tong W, Calado Nogueira de Moura V, North EJ, Sygusch J, Jackson M. | Front Microbiol | 10.3389/fmicb.2018.01547 | 2018 | | |
| Transcription of genes involved in sulfolipid and polyacyltrehalose biosynthesis of Mycobacterium tuberculosis in experimental latent tuberculosis infection. | Rodriguez JE, Ramirez AS, Salas LP, Helguera-Repetto C, Gonzalez-y-Merchand J, Soto CY, Hernandez-Pando R. | PLoS One | 10.1371/journal.pone.0058378 | 2013 | | |
| Pathogenicity | Whole-Cell Screen of Fragment Library Identifies Gut Microbiota Metabolite Indole Propionic Acid as Antitubercular. | Negatu DA, Liu JJJ, Zimmerman M, Kaya F, Dartois V, Aldrich CC, Gengenbacher M, Dick T. | Antimicrob Agents Chemother | 10.1128/aac.01571-17 | 2018 | |
| Enzymology | glpx Gene in Mycobacterium tuberculosis Is Required for In Vitro Gluconeogenic Growth and In Vivo Survival. | Gutka HJ, Wang Y, Franzblau SG, Movahedzadeh F. | PLoS One | 10.1371/journal.pone.0138436 | 2015 | |
| Metabolism | IL-36/LXR axis modulates cholesterol metabolism and immune defense to Mycobacterium tuberculosis. | Ahsan F, Maertzdorf J, Guhlich-Bornhof U, Kaufmann SHE, Moura-Alves P. | Sci Rep | 10.1038/s41598-018-19476-x | 2018 | |
| Histopathological Study of the Lungs of Mice Receiving Human Secretory IgA and Challenged with Mycobacterium tuberculosis. | Alvarez N, Infante JF, Borrero R, Mata D, Payan JB, Hossain MM, Mohd Nor N, Sarmiento ME, Hernandez-Pando R, Acosta A. | Malays J Med Sci | 2014 | | ||
| Novel Acetamide Indirectly Targets Mycobacterial Transporter MmpL3 by Proton Motive Force Disruption. | Shetty A, Xu Z, Lakshmanan U, Hill J, Choong ML, Chng SS, Yamada Y, Poulsen A, Dick T, Gengenbacher M. | Front Microbiol | 10.3389/fmicb.2018.02960 | 2018 | | |
| Molecular typing of Iranian mycobacteria isolates by polymerase chain reaction-restriction fragment length polymorphism analysis of 360-bp rpoB gene. | Hadifar S, Moghim S, Fazeli H, GhasemianSafaei H, Havaei SA, Farid F, Esfahani BN. | Adv Biomed Res | 10.4103/2277-9175.161579 | 2015 | | |
| Bayesian Assessment of the Accuracy of a PCR-Based Rapid Diagnostic Test for Bovine Tuberculosis in Swine. | Barandiaran S, Perez Aguirreburualde MS, Marfil MJ, Martinez Vivot M, Aznar N, Zumarraga M, Perez AM. | Front Vet Sci | 10.3389/fvets.2019.00204 | 2019 | | |
| Pathogenicity | Prevalence and drug resistance of mycobacteria in Turkish cystic fibrosis patients. | Satana D, Erkose-Genc G, Tamay Z, Uzun M, Guler N, Erturan Z. | Ann Clin Microbiol Antimicrob | 10.1186/1476-0711-13-28 | 2014 | |
| Bortezomib Warhead-Switch Confers Dual Activity against Mycobacterial Caseinolytic Protease and Proteasome and Selectivity against Human Proteasome. | Moreira W, Santhanakrishnan S, Dymock BW, Dick T. | Front Microbiol | 10.3389/fmicb.2017.00746 | 2017 | | |
| Pathogenicity | Anti-Mycobacterium tuberculosis activity and cytotoxicity of Calophyllum brasiliense Cambess (Clusiaceae). | Pires CT, Brenzan MA, Scodro RB, Cortez DA, Lopes LD, Siqueira VL, Cardoso RF. | Mem Inst Oswaldo Cruz | 10.1590/0074-0276130323 | 2014 | |
| An Insight into Fluorinated Imines and Hydrazones as Antibacterial Agents. | Sztanke M, Wilk A, Sztanke K. | Int J Mol Sci | 10.3390/ijms25063341 | 2024 | | |
| Activity of a Long-Acting Injectable Bedaquiline Formulation in a Paucibacillary Mouse Model of Latent Tuberculosis Infection. | Kaushik A, Ammerman NC, Tyagi S, Saini V, Vervoort I, Lachau-Durand S, Nuermberger E, Andries K. | Antimicrob Agents Chemother | 10.1128/aac.00007-19 | 2019 | | |
| Rapid identification of mycobacteria and drug-resistant Mycobacterium tuberculosis by use of a single multiplex PCR and DNA sequencing. | Perez-Osorio AC, Boyle DS, Ingham ZK, Ostash A, Gautom RK, Colombel C, Houze Y, Leader BT. | J Clin Microbiol | 10.1128/jcm.05570-11 | 2012 | | |
| Prevalence and Drug Resistance Patterns of Mycobacterium tuberculosis among New Smear Positive Pulmonary Tuberculosis Patients in Eastern Ethiopia. | Seyoum B, Demissie M, Worku A, Bekele S, Aseffa A. | Tuberc Res Treat | 10.1155/2014/753492 | 2014 | | |
| Mycobacterium tuberculosis-Induced Polarization of Human Macrophage Orchestrates the Formation and Development of Tuberculous Granulomas In Vitro. | Huang Z, Luo Q, Guo Y, Chen J, Xiong G, Peng Y, Ye J, Li J. | PLoS One | 10.1371/journal.pone.0129744 | 2015 | | |
| Synthesis and antituberculosis activity of new thiazolylhydrazone derivatives. | Turan-Zitouni G, Ozdemir A, Kaplancikli ZA, Benkli K, Chevallet P, Akalin G. | Eur J Med Chem | 10.1016/j.ejmech.2007.07.001 | 2008 | | |
| Pathogenicity | Correlation of different phenotypic drug susceptibility testing methods for four fluoroquinolones in Mycobacterium tuberculosis. | Coeck N, de Jong BC, Diels M, de Rijk P, Ardizzoni E, Van Deun A, Rigouts L. | J Antimicrob Chemother | 10.1093/jac/dkv499 | 2016 | |
| Enzymology | Performance of nucleic acid amplification following extraction of 5 milliliters of whole blood for diagnosis of Mycobacterium tuberculosis bacteremia. | Crump JA, Tuohy MJ, Morrissey AB, Ramadhani HO, Njau BN, Maro VP, Reller LB, Procop GW. | J Clin Microbiol | 10.1128/jcm.05963-11 | 2012 | |
| Pathogenicity | Locked Nucleic Acid Probe-Based Real-Time PCR Assay for the Rapid Detection of Rifampin-Resistant Mycobacterium tuberculosis. | Zhao Y, Li G, Sun C, Li C, Wang X, Liu H, Zhang P, Zhao X, Wang X, Jiang Y, Yang R, Wan K, Zhou L. | PLoS One | 10.1371/journal.pone.0143444 | 2015 | |
| A novel recombinant DNA vaccine encoding Mycobacterium tuberculosis ESAT-6 and FL protects against Mycobacterium tuberculosis challenge in mice. | Jiang Q, Zhang J, Chen X, Xia M, Lu Y, Qiu W, Feng G, Zhao D, Li Y, He F, Peng G, Wang Y. | J Biomed Res | 10.7555/jbr.27.20120114 | 2013 | | |
| Pathogenicity | Nanostructured lipid carriers for incorporation of copper(II) complexes to be used against Mycobacterium tuberculosis. | Sato MR, Oshiro Junior JA, Machado RT, de Souza PC, Campos DL, Pavan FR, da Silva PB, Chorilli M. | Drug Des Devel Ther | 10.2147/dddt.s127048 | 2017 | |
| Clinical utility of RD1, RD9 and hsp65 based PCR assay for the identification of BCG in vaccinated children. | Teo JW, Cheng JW, Jureen R, Lin RT. | BMC Res Notes | 10.1186/1756-0500-6-434 | 2013 | | |
| Pathogenicity | Antibacterial and Sterilizing Effect of Benzylpenicillin in Tuberculosis. | Deshpande D, Srivastava S, Bendet P, Martin KR, Cirrincione KN, Lee PS, Pasipanodya JG, Dheda K, Gumbo T. | Antimicrob Agents Chemother | 10.1128/aac.02232-17 | 2018 | |
| Pathogenicity | Multicenter evaluation of Bactec MGIT 960 system for second-line drug susceptibility testing of Mycobacterium tuberculosis complex. | Lin SY, Desmond E, Bonato D, Gross W, Siddiqi S. | J Clin Microbiol | 10.1128/jcm.00803-09 | 2009 | |
| Transcriptome | Antimycobacterial Activity: A New Pharmacological Target for Conotoxins Found in the First Reported Conotoxin from Conasprella ximenes. | Figueroa-Montiel A, Bernaldez J, Jimenez S, Ueberhide B, Gonzalez LJ, Licea-Navarro A. | Toxins (Basel) | 10.3390/toxins10020051 | 2018 | |
| Pathogenicity | Nanostructured lipid systems as a strategy to improve the in vitro cytotoxicity of ruthenium(II) compounds. | de Freitas ES, da Silva PB, Chorilli M, Batista AA, de Oliveira Lopes E, da Silva MM, Leite CQ, Pavan FR. | Molecules | 10.3390/molecules19055999 | 2014 | |
| The alr-groEL1 operon in Mycobacterium tuberculosis: an interplay of multiple regulatory elements. | Bhat AH, Pathak D, Rao A. | Sci Rep | 10.1038/srep43772 | 2017 | | |
| Pathogenicity | Potential mechanism of action of meso-dihydroguaiaretic acid on Mycobacterium tuberculosis H37Rv. | Clemente-Soto AF, Balderas-Renteria I, Rivera G, Segura-Cabrera A, Garza-Gonzalez E, del Rayo Camacho-Corona M. | Molecules | 10.3390/molecules191220170 | 2014 | |
| Enzymology | Analytical Performance of a Loop-Mediated Isothermal Amplification Assay for Leishmania DNA Detection in Sandflies and Direct Smears of Patients with Cutaneous Leishmaniasis. | Leon CM, Munoz M, Tabares JH, Hernandez C, Florez C, Ayala MS, Ramirez JD. | Am J Trop Med Hyg | 10.4269/ajtmh.17-0808 | 2018 | |
| Pathogenicity | A 24-well plate assay for simultaneous testing of first and second line drugs against Mycobacterium tuberculosis in a high endemic setting. | Wedajo W, Schon T, Bedru A, Kiros T, Hailu E, Mebrahtu T, Yamuah L, Angeby K, Werngren J, Onyebujoh P, Dagne K, Aseffa A. | BMC Res Notes | 10.1186/1756-0500-7-512 | 2014 | |
| Enzymology | Novel multiplex PCR using dual-priming oligonucleotides for detection and discrimination of the Mycobacterium tuberculosis complex and M. bovis BCG. | Lee HR, Kim SY, Chang HE, Song SH, Lee HS, Park KU, Song J, Kim EC. | J Clin Microbiol | 10.1128/jcm.00872-10 | 2010 | |
| Antimycobacterial and cytotoxicity activity of microcystins. | Ramos DF, Matthiensen A, Colvara W, de Votto AP, Trindade GS, da Silva PE, Yunes JS. | J Venom Anim Toxins Incl Trop Dis | 10.1186/s40409-015-0009-8 | 2015 | | |
| Novel Pharmacological Activity of Artesunate and Artemisinin: Their Potential as Anti-Tubercular Agents. | Choi WH. | J Clin Med | 10.3390/jcm6030030 | 2017 | | |
| Pathogenicity | A Multilaboratory, Multicountry Study To Determine MIC Quality Control Ranges for Phenotypic Drug Susceptibility Testing of Selected First-Line Antituberculosis Drugs, Second-Line Injectables, Fluoroquinolones, Clofazimine, and Linezolid. | Kaniga K, Cirillo DM, Hoffner S, Ismail NA, Kaur D, Lounis N, Metchock B, Pfyffer GE, Venter A. | J Clin Microbiol | 10.1128/jcm.01138-16 | 2016 | |
| Pathogenicity | Analysis of embCAB mutations associated with ethambutol resistance in multidrug-resistant mycobacterium tuberculosis isolates from China. | Zhao LL, Sun Q, Liu HC, Wu XC, Xiao TY, Zhao XQ, Li GL, Jiang Y, Zeng CY, Wan KL. | Antimicrob Agents Chemother | 10.1128/aac.04933-14 | 2015 | |
| Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity. | Govender P, Muller R, Singh K, Reddy V, Eyermann CJ, Fienberg S, Ghorpade SR, Koekemoer L, Myrick A, Schnappinger D, Engelhart C, Meshanni J, Byl JAW, Osheroff N, Singh V, Chibale K, Basarab GS. | J Med Chem | 10.1021/acs.jmedchem.2c00266 | 2022 | | |
| Pathogenicity | Phenotypic and genotypic characterization of pyrazinamide resistance among multidrug-resistant Mycobacterium tuberculosis isolates in Zhejiang, China. | Xia Q, Zhao LL, Li F, Fan YM, Chen YY, Wu BB, Liu ZW, Pan AZ, Zhu M. | Antimicrob Agents Chemother | 10.1128/aac.04541-14 | 2015 | |
| Enzymology | [Chemical constituents and anti-tuberculosis activity of root of Rhodiola kirilowii]. | Wong YC, Zhao M, Zong YY, Chan CY, Che CT. | Zhongguo Zhong Yao Za Zhi | 2008 | | |
| Mycobacterium tuberculosis GrpE, A Heat-Shock Stress Responsive Chaperone, Promotes Th1-Biased T Cell Immune Response via TLR4-Mediated Activation of Dendritic Cells. | Kim WS, Jung ID, Kim JS, Kim HM, Kwon KW, Park YM, Shin SJ. | Front Cell Infect Microbiol | 10.3389/fcimb.2018.00095 | 2018 | | |
| Pathogenicity | Comparison and development of pyrazinamide susceptibility testing methods for tuberculosis in Thailand. | Foongladda S, Klayut W, Pholwat S, Houpt E. | Diagn Microbiol Infect Dis | 10.1016/j.diagmicrobio.2015.07.008 | 2015 | |
| Curcumin Nanoparticles Enhance Mycobacterium bovis BCG Vaccine Efficacy by Modulating Host Immune Responses. | Ahmad S, Bhattacharya D, Kar S, Ranganathan A, Van Kaer L, Das G. | Infect Immun | 10.1128/iai.00291-19 | 2019 | | |
| Pathogenicity | Functional, thermodynamics, structural and biological studies of in silico-identified inhibitors of Mycobacterium tuberculosis enoyl-ACP(CoA) reductase enzyme. | Martinelli LKB, Rotta M, Villela AD, Rodrigues-Junior VS, Abbadi BL, Trindade RV, Petersen GO, Danesi GM, Nery LR, Pauli I, Campos MM, Bonan CD, de Souza ON, Basso LA, Santos DS. | Sci Rep | 10.1038/srep46696 | 2017 | |
| Cell wall skeleton of Mycobacterium bovis BCG enhances the vaccine potential of antigen 85B against tuberculosis by inducing Th1 and Th17 responses. | Back YW, Choi S, Choi HG, Shin KW, Son YJ, Paik TH, Kim HJ. | PLoS One | 10.1371/journal.pone.0213536 | 2019 | | |
| Enzymology | Protein-coding housekeeping gene Rv2461c can be used as an amplification target in loop-mediated isothermal amplification assay for the detection of Mycobacterium tuberculosis in sputum samples. | Li D, Zhao J, Nie X, Wan T, Xu W, Zhao Y. | Int J Clin Exp Pathol | 2014 | | |
| One-Step PCR Detection of Salmonella Pullorum/Gallinarum Using a Novel Target: The Flagellar Biosynthesis Gene flhB. | Xiong D, Song L, Geng S, Tao J, An S, Pan Z, Jiao X. | Front Microbiol | 10.3389/fmicb.2016.01863 | 2016 | | |
| Pathogenicity | Ureidopyrazine Derivatives: Synthesis and Biological Evaluation as Anti-Infectives and Abiotic Elicitors. | Bouz G, Juhas M, Niklova P, Jandourek O, Paterova P, Janousek J, Tumova L, Kovalikova Z, Kastner P, Dolezal M, Zitko J. | Molecules | 10.3390/molecules22101797 | 2017 | |
| Evaluation of the effect of Humulus lupulus alcoholic extract on rifampin-sensitive and resistant isolates of Mycobacterium tuberculosis. | Serkani JE, Isfahani BN, Safaei HG, Kermanshahi RK, Asghari G. | Res Pharm Sci | 2012 | | ||
| Comparative Study of a Real-Time PCR Assay Targeting senX3-regX3 versus Other Molecular Strategies Commonly Used in the Diagnosis of Tuberculosis. | Sanjuan-Jimenez R, Toro-Peinado I, Bermudez P, Colmenero JD, Morata P. | PLoS One | 10.1371/journal.pone.0143025 | 2015 | | |
| Metabolism | Naturally Occurring Calanolides: Occurrence, Biosynthesis, and Pharmacological Properties Including Therapeutic Potential. | Nahar L, Talukdar AD, Nath D, Nath S, Mehan A, Ismail FMD, Sarker SD. | Molecules | 10.3390/molecules25214983 | 2020 | |
| Rapid diagnosis of Mycoplasma pneumonia infection by denaturation bubble-mediated strand exchange amplification: comparison with LAMP and real-time PCR. | Shi W, Wei M, Wang Q, Wang H, Ma C, Shi C. | Sci Rep | 10.1038/s41598-018-36751-z | 2019 | | |
| Pathogenicity | Mycobacterium tuberculosis gyrase inhibitors as a new class of antitubercular drugs. | Blanco D, Perez-Herran E, Cacho M, Ballell L, Castro J, Gonzalez Del Rio R, Lavandera JL, Remuinan MJ, Richards C, Rullas J, Vazquez-Muniz MJ, Woldu E, Zapatero-Gonzalez MC, Angulo-Barturen I, Mendoza A, Barros D. | Antimicrob Agents Chemother | 10.1128/aac.03913-14 | 2015 | |
| Enzymology | Proteomics Analysis of Three Different Strains of Mycobacterium tuberculosis under In vitro Hypoxia and Evaluation of Hypoxia Associated Antigen's Specific Memory T Cells in Healthy Household Contacts. | Devasundaram S, Gopalan A, Das SD, Raja A. | Front Microbiol | 10.3389/fmicb.2016.01275 | 2016 | |
| Development of a Duplex TaqMan Real-Time Polymerase Chain Reaction for Accurate Identification and Quantification of Salmonella Enteritidis from Laboratory Samples and Contaminated Chicken Eggs. | Xiong D, Zhou Y, Song L, Liu B, Matchawe C, Chen X, Pelle R, Jiao X, Pan Z. | Foods | 10.3390/foods11050742 | 2022 | | |
| Pathogenicity | Synthesis of novel 5-aryl-2-thio-1,3,4-oxadiazoles and the study of their structure-anti-mycobacterial activities. | Macaev F, Rusu G, Pogrebnoi S, Gudima A, Stingaci E, Vlad L, Shvets N, Kandemirli F, Dimoglo A, Reynolds R. | Bioorg Med Chem | 10.1016/j.bmc.2005.05.011 | 2005 | |
| Pathogenicity | Anti-mycobacterial activity of marine fungus-derived 4-deoxybostrycin and nigrosporin. | Wang C, Wang J, Huang Y, Chen H, Li Y, Zhong L, Chen Y, Chen S, Wang J, Kang J, Peng Y, Yang B, Lin Y, She Z, Lai X. | Molecules | 10.3390/molecules18021728 | 2013 | |
| Pathogenicity | Esters of Pyrazinoic Acid Are Active against Pyrazinamide-Resistant Strains of Mycobacterium tuberculosis and Other Naturally Resistant Mycobacteria In Vitro and Ex Vivo within Macrophages. | Pires D, Valente E, Simoes MF, Carmo N, Testa B, Constantino L, Anes E. | Antimicrob Agents Chemother | 10.1128/aac.00936-15 | 2015 | |
| Phylogeny | Single-nucleotide polymorphisms in Rv2629 are specific for Mycobacterium tuberculosis genotypes Beijing and Ghana but not associated with rifampin resistance. | Homolka S, Koser C, Archer J, Rusch-Gerdes S, Niemann S. | J Clin Microbiol | 10.1128/jcm.01237-08 | 2009 | |
| Synthesis and preliminary screening of carbohydrazides and hydrazones of pyrrole derivatives as potential tuberculostatics. | Bijev A. | Arzneimittelforschung | 10.1055/s-0031-1296708 | 2006 | | |
| Metabolism | Engineering more stable, selectable marker-free autoluminescent mycobacteria by one step. | Yang F, Njire MM, Liu J, Wu T, Wang B, Liu T, Cao Y, Liu Z, Wan J, Tu Z, Tan Y, Tan S, Zhang T. | PLoS One | 10.1371/journal.pone.0119341 | 2015 | |
| Prevalence and drug resistance profile of Mycobacterium tuberculosis isolated from pulmonary tuberculosis patients attending two public hospitals in East Gojjam zone, northwest Ethiopia. | Adane K, Ameni G, Bekele S, Abebe M, Aseffa A. | BMC Public Health | 10.1186/s12889-015-1933-9 | 2015 | | |
| Metabolism | Rapid and spontaneous loss of phthiocerol dimycocerosate (PDIM) from Mycobacterium tuberculosis grown in vitro: implications for virulence studies. | Domenech P, Reed MB. | Microbiology (Reading) | 10.1099/mic.0.029199-0 | 2009 | |
| Pathogenicity | Synthesis, tuberculosis inhibitory activity, and SAR study of N-substituted-phenyl-1,2,3-triazole derivatives. | Costa MS, Boechat N, Rangel EA, da Silva Fde C, de Souza AM, Rodrigues CR, Castro HC, Junior IN, Lourenco MC, Wardell SM, Ferreira VF. | Bioorg Med Chem | 10.1016/j.bmc.2006.08.019 | 2006 | |
| Performance Evaluation of the PowerChek MERS (upE & ORF1a) Real-Time PCR Kit for the Detection of Middle East Respiratory Syndrome Coronavirus RNA. | Huh HJ, Kim JY, Kwon HJ, Yun SA, Lee MK, Ki CS, Lee NY, Kim JW. | Ann Lab Med | 10.3343/alm.2017.37.6.494 | 2017 | | |
| Pathogenicity | Molecular analysis of codon 548 in the rpoB gene involved in Mycobacterium tuberculosis resistance to rifampin. | Horng YT, Jeng WY, Chen YY, Liu CH, Dou HY, Lee JJ, Chang KC, Chien CC, Soo PC. | Antimicrob Agents Chemother | 10.1128/aac.04374-14 | 2015 | |
| Synthesis and antituberculosis activity of new 3-alkylsulfanyl-1,2,4-triazole derivatives. | Kaplancikli ZA, Turan-Zitouni G, Chevallet P. | J Enzyme Inhib Med Chem | 10.1080/14756360500043471 | 2005 | | |
| Metabolism | Rifampin induces hydroxyl radical formation in Mycobacterium tuberculosis. | Piccaro G, Pietraforte D, Giannoni F, Mustazzolu A, Fattorini L. | Antimicrob Agents Chemother | 10.1128/aac.03169-14 | 2014 | |
| Metabolism | Impact of Mycobacterium tuberculosis RD1-locus on human primary dendritic cell immune functions. | Etna MP, Giacomini E, Pardini M, Severa M, Bottai D, Cruciani M, Rizzo F, Calogero R, Brosch R, Coccia EM. | Sci Rep | 10.1038/srep17078 | 2015 | |
| Phylogeny | Mycobacterium bovis isolates with M. tuberculosis specific characteristics. | Kubica T, Agzamova R, Wright A, Rakishev G, Rusch-Gerdes S, Niemann S. | Emerg Infect Dis | 10.3201/eid1205.050200 | 2006 | |
| Metabolism | Unique Regulation of the DosR Regulon in the Beijing Lineage of Mycobacterium tuberculosis. | Domenech P, Zou J, Averback A, Syed N, Curtis D, Donato S, Reed MB. | J Bacteriol | 10.1128/jb.00696-16 | 2017 | |
| Fragment-Based Whole Cell Screen Delivers Hits against M. tuberculosis and Non-tuberculous Mycobacteria. | Moreira W, Lim JJ, Yeo SY, Ramanujulu PM, Dymock BW, Dick T. | Front Microbiol | 10.3389/fmicb.2016.01392 | 2016 | | |
| Structome analysis of virulent Mycobacterium tuberculosis, which survives with only 700 ribosomes per 0.1 fl of cytoplasm. | Yamada H, Yamaguchi M, Chikamatsu K, Aono A, Mitarai S. | PLoS One | 10.1371/journal.pone.0117109 | 2015 | | |
| Antitubercular agents. Part 1: synthesis of phthalimido- and naphthalimido-linked phenazines as new prototype antitubercular agents. | Kamal A, Hari Babu A, Venkata Ramana A, Sinha R, Yadav JS, Arora SK. | Bioorg Med Chem Lett | 10.1016/j.bmcl.2005.01.085 | 2005 | | |
| High Persister Mutants in Mycobacterium tuberculosis. | Torrey HL, Keren I, Via LE, Lee JS, Lewis K. | PLoS One | 10.1371/journal.pone.0155127 | 2016 | | |
| Pathogenicity | Mutations Found in embCAB, embR, and ubiA Genes of Ethambutol-Sensitive and -Resistant Mycobacterium tuberculosis Clinical Isolates from China. | Xu Y, Jia H, Huang H, Sun Z, Zhang Z. | Biomed Res Int | 10.1155/2015/951706 | 2015 | |
| Pathogenicity | Antimicrobial and cytotoxicity properties of the crude extracts and fractions of Premna resinosa (Hochst.) Schauer (Compositae): Kenyan traditional medicinal plant. | Njeru SN, Obonyo MA, Nyambati SO, Ngari SM. | BMC Complement Altern Med | 10.1186/s12906-015-0811-4 | 2015 | |
| A study of Mycobacterium tuberculosis genotypic diversity & drug resistance mutations in Varanasi, north India. | Gupta A, Kulkarni S, Rastogi N, Anupurba S. | Indian J Med Res | 2014 | | ||
| Enzymology | Comparison of six methods of extracting Mycobacterium tuberculosis DNA from processed sputum for testing by quantitative real-time PCR. | Aldous WK, Pounder JI, Cloud JL, Woods GL. | J Clin Microbiol | 10.1128/jcm.43.5.2471-2473.2005 | 2005 | |
| Pathogenicity | In vitro postantibiotic effects of rifapentine, isoniazid, and moxifloxacin against Mycobacterium tuberculosis. | Chan CY, Au-Yeang C, Yew WW, Leung CC, Cheng AF. | Antimicrob Agents Chemother | 10.1128/aac.48.1.340-343.2004 | 2004 | |
| Enzymology | Performance of Xpert MTB/RIF RUO assay and IS6110 real-time PCR for Mycobacterium tuberculosis detection in clinical samples. | Miller MB, Popowitch EB, Backlund MG, Ager EP. | J Clin Microbiol | 10.1128/jcm.05212-11 | 2011 | |
| Pathogenicity | Synthesis and antituberculosis activity of cycloalkylidenehydrazide and 4-aza-1-thiaspiro[4.5]decan-3-one derivatives of imidazo[2,1-b]thiazole. | Ulusoy N. | Arzneimittelforschung | 10.1055/s-0031-1299931 | 2002 | |
| Metabolism | Evaluation of peptide nucleic acid probe-based real-time PCR for detection of Mycobacterium tuberculosis complex and nontuberculous mycobacteria in respiratory specimens. | Choi YJ, Kim HJ, Shin HB, Nam HS, Lee SH, Park JS, Park KS, Baek KA. | Ann Lab Med | 10.3343/alm.2012.32.4.257 | 2012 | |
| Derivatives of 3-Aminopyrazine-2-carboxamides: Synthesis, Antimicrobial Evaluation, and in Vitro Cytotoxicity. | Bouz G, Semelkova L, Jandourek O, Konecna K, Paterova P, Navratilova L, Kubicek V, Kunes J, Dolezal M, Zitko J. | Molecules | 10.3390/molecules24071212 | 2019 | | |
| Enzymology | Pyrazinamide susceptibility testing of Mycobacterium tuberculosis by high resolution melt analysis. | Pholwat S, Stroup S, Gratz J, Trangan V, Foongladda S, Kumburu H, Juma SP, Kibiki G, Houpt E. | Tuberculosis (Edinb) | 10.1016/j.tube.2013.10.006 | 2014 | |
| A Review of Modifications of Quinoline Antimalarials: Mefloquine and (hydroxy)Chloroquine. | Kucharski DJ, Jaszczak MK, Boratynski PJ. | Molecules | 10.3390/molecules27031003 | 2022 | | |
| Metabolism | Rv2744c Is a PspA Ortholog That Regulates Lipid Droplet Homeostasis and Nonreplicating Persistence in Mycobacterium tuberculosis. | Armstrong RM, Adams KL, Zilisch JE, Bretl DJ, Sato H, Anderson DM, Zahrt TC. | J Bacteriol | 10.1128/jb.01001-15 | 2016 | |
| Role of pncA and rpsA gene sequencing in detection of pyrazinamide resistance in Mycobacterium tuberculosis isolates from southern China. | Tan Y, Hu Z, Zhang T, Cai X, Kuang H, Liu Y, Chen J, Yang F, Zhang K, Tan S, Zhao Y. | J Clin Microbiol | 10.1128/jcm.01903-13 | 2014 | | |
| Pathogenicity | Bactericidal activity and mechanism of action of AZD5847, a novel oxazolidinone for treatment of tuberculosis. | Balasubramanian V, Solapure S, Iyer H, Ghosh A, Sharma S, Kaur P, Deepthi R, Subbulakshmi V, Ramya V, Ramachandran V, Balganesh M, Wright L, Melnick D, Butler SL, Sambandamurthy VK. | Antimicrob Agents Chemother | 10.1128/aac.01903-13 | 2014 | |
| Metabolism | Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes. | Howard NC, Marin ND, Ahmed M, Rosa BA, Martin J, Bambouskova M, Sergushichev A, Loginicheva E, Kurepina N, Rangel-Moreno J, Chen L, Kreiswirth BN, Klein RS, Klein RS, Balada-Llasat JM, Torrelles JB, Amarasinghe GK, Mitreva M, Artyomov MN, Hsu FF, Mathema B, Khader SA. | Nat Microbiol | 10.1038/s41564-018-0245-0 | 2018 | |
| Roles of endoplasmic reticulum stress-mediated apoptosis in M1-polarized macrophages during mycobacterial infections. | Lim YJ, Yi MH, Choi JA, Lee J, Han JY, Jo SH, Oh SM, Cho HJ, Kim DW, Kang MW, Song CH. | Sci Rep | 10.1038/srep37211 | 2016 | | |
| Pathogenicity | In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis that are susceptible or resistant to first-line antituberculous drugs. | Alcala L, Ruiz-Serrano MJ, Perez-Fernandez Turegano C, Garcia De Viedma D, Diaz-Infantes M, Marin-Arriaza M, Bouza E. | Antimicrob Agents Chemother | 10.1128/aac.47.1.416-417.2003 | 2003 | |
| Metabolism | HIV-1 Tat protein vaccination in mice infected with Mycobacterium tuberculosis is safe, immunogenic and reduces bacterial lung pathology. | Cafaro A, Piccaro G, Altavilla G, Gigantino V, Matarese G, Olivieri E, Ferrantelli F, Ensoli B, Palma C. | BMC Infect Dis | 10.1186/s12879-016-1724-7 | 2016 | |
| Metabolism | Rv1218c, an ABC transporter of Mycobacterium tuberculosis with implications in drug discovery. | Balganesh M, Kuruppath S, Marcel N, Sharma S, Nair A, Sharma U. | Antimicrob Agents Chemother | 10.1128/aac.00610-10 | 2010 | |
| Pathogenicity | Versatility of 7-Substituted Coumarin Molecules as Antimycobacterial Agents, Neuronal Enzyme Inhibitors and Neuroprotective Agents. | Kapp E, Visser H, Sampson SL, Malan SF, Streicher EM, Foka GB, Warner DF, Omoruyi SI, Enogieru AB, Ekpo OE, Zindo FT, Joubert J. | Molecules | 10.3390/molecules22101644 | 2017 | |
| Rv2629 Overexpression Delays Mycobacterium smegmatis and Mycobacteria tuberculosis Entry into Log-Phase and Increases Pathogenicity of Mycobacterium smegmatis in Mice. | Liu D, Hao K, Wang W, Peng C, Dai Y, Jin R, Xu W, He L, Wang H, Wang H, Zhang L, Wang Q. | Front Microbiol | 10.3389/fmicb.2017.02231 | 2017 | | |
| Enzymology | Accurate, rapid and low-cost diagnosis of Mycoplasma pneumoniae via fast narrow-thermal-cycling denaturation bubble-mediated strand exchange amplification. | Yang C, Li Y, Deng J, Li M, Ma C, Shi C. | Anal Bioanal Chem | 10.1007/s00216-020-02977-y | 2020 | |
| Relatively low primary drug resistant tuberculosis in southwestern Ethiopia. | Abebe G, Abdissa K, Abdissa A, Apers L, Agonafir M, de-Jong BC, Colebunders R. | BMC Res Notes | 10.1186/1756-0500-5-225 | 2012 | | |
| Pathogenicity | In vitro activities of cloxyquin (5-chloroquinolin-8-ol) against Mycobacterium tuberculosis. | Hongmanee P, Rukseree K, Buabut B, Somsri B, Palittapongarnpim P. | Antimicrob Agents Chemother | 10.1128/aac.01310-06 | 2007 | |
| Rapid genotypic detection of rpoB and katG gene mutations in Mycobacterium tuberculosis clinical isolates from Northern India as determined by MAS-PCR. | Gupta A, Prakash P, Singh SK, Anupurba S. | J Clin Lab Anal | 10.1002/jcla.21558 | 2013 | | |
| Challenge in the Discovery of New Drugs: Antimicrobial Peptides against WHO-List of Critical and High-Priority Bacteria. | Roque-Borda CA, da Silva PB, Rodrigues MC, Azevedo RB, Di Filippo L, Duarte JL, Chorilli M, Festozo Vicente E, Pavan FR. | Pharmaceutics | 10.3390/pharmaceutics13060773 | 2021 | | |
| Pathogenicity | Activity of a new class of isonicotinoylhydrazones used alone and in combination with isoniazid, rifampicin, ethambutol, para-aminosalicylic acid and clofazimine against Mycobacterium tuberculosis. | De Logu A, Onnis V, Saddi B, Congiu C, Schivo ML, Cocco MT. | J Antimicrob Chemother | 10.1093/jac/49.2.275 | 2002 | |
| Discovery of Indeno[1,2-c]quinoline Derivatives as Potent Dual Antituberculosis and Anti-Inflammatory Agents. | Tseng CH, Tung CW, Wu CH, Tzeng CC, Chen YH, Hwang TL, Chen YL. | Molecules | 10.3390/molecules22061001 | 2017 | | |
| Unprecedented in Vitro Antitubercular Activitiy of Manganese(II) Complexes Containing 1,10-Phenanthroline and Dicarboxylate Ligands: Increased Activity, Superior Selectivity, and Lower Toxicity in Comparison to Their Copper(II) Analogs. | McCarron P, McCann M, Devereux M, Kavanagh K, Skerry C, Karakousis PC, Aor AC, Mello TP, Santos ALS, Campos DL, Pavan FR. | Front Microbiol | 10.3389/fmicb.2018.01432 | 2018 | | |
| Pathogenicity | Antiprotozoal and antimycobacterial activities of Persea americana seeds. | Jimenez-Arellanes A, Luna-Herrera J, Ruiz-Nicolas R, Cornejo-Garrido J, Tapia A, Yepez-Mulia L. | BMC Complement Altern Med | 10.1186/1472-6882-13-109 | 2013 | |
| Pathogenicity | Fast test for assessing the susceptibility of Mycobacterium tuberculosis to isoniazid and rifampin by real-time PCR. | Goncalves MG, Fukasawa LO, Oliveira RS, Salgado MM, Harrison LH, Shutt KA, Sacchi CT. | Mem Inst Oswaldo Cruz | 10.1590/s0074-02762012000700011 | 2012 | |
| Antimycobacterial activity of 1-substituted indolizines. | Gundersen LL, Negussie AH, Rise F, OStby OB. | Arch Pharm (Weinheim) | 10.1002/ardp.200390019 | 2003 | | |
| Phylogeny | Mycobacterium tuberculosis of the RDRio genotype is the predominant cause of tuberculosis and associated with multidrug resistance in Porto Alegre City, South Brazil. | Dalla Costa ER, Lazzarini LC, Perizzolo PF, Diaz CA, Spies FS, Costa LL, Ribeiro AW, Barroco C, Schuh SJ, da Silva Pereira MA, Dias CF, Gomes HM, Unis G, Zaha A, Almeida da Silva PE, Suffys PN, Rossetti ML. | J Clin Microbiol | 10.1128/jcm.01511-12 | 2013 | |
| Differential influence of nutrient-starved Mycobacterium tuberculosis on adaptive immunity results in progressive tuberculosis disease and pathology. | Dietrich J, Roy S, Rosenkrands I, Lindenstrom T, Filskov J, Rasmussen EM, Cassidy J, Andersen P. | Infect Immun | 10.1128/iai.01055-15 | 2015 | | |
| Pathogenicity | Development of small-molecule inhibitors of fatty acyl-AMP and fatty acyl-CoA ligases in Mycobacterium tuberculosis. | Baran M, Grimes KD, Sibbald PA, Fu P, Boshoff HIM, Wilson DJ, Aldrich CC. | Eur J Med Chem | 10.1016/j.ejmech.2020.112408 | 2020 | |
| Synthesis and structure activity relationships of cyanopyridone based anti-tuberculosis agents. | Jian Y, Hulpia F, Risseeuw MDP, Forbes HE, Munier-Lehmann H, Caljon G, Boshoff HIM, Van Calenbergh S. | Eur J Med Chem | 10.1016/j.ejmech.2020.112450 | 2020 | | |
| Pathogenicity | Synthesis and evaluation of in vitro antimycobacterial activity of some 5-(5-nitro-2-thienyl)-2-(piperazinyl, piperidinyl and morpholinyl)-1,3,4-thiadiazole derivatives. | Foroumadi A, Soltani F, Rezaee MA, Moshafi MH. | Boll Chim Farm | 2003 | | |
| First-line anti-tubercular drug resistance of mycobacterial strains from re-treatment cases that were smear-positive at 4(th) month onwards under the Revised National Tuberculosis Control Program. | Lahiri S, Mukherjee A, Hazra S, Jana P, Roy S, Saha BK. | Lung India | 10.4103/0970-2113.152619 | 2015 | | |
| Pathogenicity | Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis. | Ordway D, Viveiros M, Leandro C, Bettencourt R, Almeida J, Martins M, Kristiansen JE, Molnar J, Amaral L. | Antimicrob Agents Chemother | 10.1128/aac.47.3.917-922.2003 | 2003 | |
| Pathogenicity | Sterilizing Effect of Ertapenem-Clavulanate in a Hollow-Fiber Model of Tuberculosis and Implications on Clinical Dosing. | van Rijn SP, Srivastava S, Wessels MA, van Soolingen D, Alffenaar JC, Gumbo T. | Antimicrob Agents Chemother | 10.1128/aac.02039-16 | 2017 | |
| Metabolism | Synthesis and in vitro biological evaluation of ring B abeo-sterols as novel inhibitors of Mycobacterium tuberculosis. | Wei X, Rodriguez AD, Wang Y, Franzblau SG. | Bioorg Med Chem Lett | 10.1016/j.bmcl.2008.09.029 | 2008 | |
| Anti-tuberculosis and cytotoxic evaluation of the seaweed Sargassum boveanum. | Akbari V, Zafari S, Yegdaneh A. | Res Pharm Sci | 10.4103/1735-5362.220965 | 2018 | | |
| Pathogenicity | 2-((3,5-Dinitrobenzyl)thio)quinazolinones: Potent Antimycobacterial Agents Activated by Deazaflavin (F420)-Dependent Nitroreductase (Ddn). | Jian Y, Forbes HE, Hulpia F, Risseeuw MDP, Caljon G, Munier-Lehmann H, Boshoff HIM, Van Calenbergh S. | J Med Chem | 10.1021/acs.jmedchem.0c01374 | 2021 | |
| Characterization of Intracellular Activity of Antitubercular Constituents the Roots of Euclea natalensis. | Lall N, Meyer JJM, Wang Y, Bapela NB, van Rensburg CEJ, Fourie B, Franzblau SG. | Pharm Biol | 10.1080/13880200590951829 | 2005 | | |
| Metabolism | Blockade of translationally controlled tumor protein attenuated the aggressiveness of fibroblast-like synoviocytes and ameliorated collagen-induced arthritis. | Kim M, Choe Y, Lee H, Jeon MG, Park JH, Noh HS, Cheon YH, Park HJ, Park J, Shin SJ, Lee K, Lee SI. | Exp Mol Med | 10.1038/s12276-020-00546-y | 2021 | |
| Hydride-induced Meisenheimer complex formation reflects activity of nitro aromatic anti-tuberculosis compounds. | Liu R, Markley L, Miller PA, Franzblau S, Shetye G, Ma R, Savkova K, Mikusova K, Lee BS, Pethe K, Moraski GC, Miller MJ. | RSC Med Chem | 10.1039/d0md00390e | 2021 | | |
| Pathogenicity | Design, Synthesis and Antimycobacterial Activity of Novel Imidazo[1,2-a]pyridine Amide-Cinnamamide Hybrids. | Li L, Li Z, Liu M, Shen W, Wang B, Guo H, Lu Y. | Molecules | 10.3390/molecules21010049 | 2015 | |
| Pathogenicity | Triterpenes and the antimycobacterial activity of Duroia macrophylla Huber (Rubiaceae). | Martins D, Carrion LL, Ramos DF, Salome KS, da Silva PE, Barison A, Nunez CV. | Biomed Res Int | 10.1155/2013/605831 | 2013 | |
| Pathogenicity | Structure-aided optimization of non-nucleoside M. tuberculosis thymidylate kinase inhibitors. | Song L, Merceron R, Hulpia F, Lucia A, Gracia B, Jian Y, Risseeuw MDP, Verstraelen T, Cos P, Ainsa JA, Boshoff HI, Munier-Lehmann H, Savvides SN, Van Calenbergh S. | Eur J Med Chem | 10.1016/j.ejmech.2021.113784 | 2021 | |
| Effect of an Oxadiazoline and a Lignan on Mycolic Acid Biosynthesis and Ultrastructural Changes of Mycobacterium tuberculosis. | Baquero E, Quinones W, Ribon W, Caldas ML, Sarmiento L, Echeverri F. | Tuberc Res Treat | 10.1155/2011/986409 | 2011 | | |
| Pathogenicity | Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis. | Viveiros M, Portugal I, Bettencourt R, Victor TC, Jordaan AM, Leandro C, Ordway D, Amaral L. | Antimicrob Agents Chemother | 10.1128/aac.46.9.2804-2810.2002 | 2002 | |
| Metabolism | Mycobacterium tuberculosis-induced miR-155 subverts autophagy by targeting ATG3 in human dendritic cells. | Etna MP, Sinigaglia A, Grassi A, Giacomini E, Romagnoli A, Pardini M, Severa M, Cruciani M, Rizzo F, Anastasiadou E, Di Camillo B, Barzon L, Fimia GM, Manganelli R, Coccia EM. | PLoS Pathog | 10.1371/journal.ppat.1006790 | 2018 | |
| Endoplasmic reticulum stress pathway-mediated apoptosis in macrophages contributes to the survival of Mycobacterium tuberculosis. | Lim YJ, Choi JA, Choi HH, Cho SN, Kim HJ, Jo EK, Park JK, Song CH. | PLoS One | 10.1371/journal.pone.0028531 | 2011 | | |
| T cells from Programmed Death-1 deficient mice respond poorly to Mycobacterium tuberculosis infection. | Tousif S, Singh Y, Prasad DV, Sharma P, Van Kaer L, Das G. | PLoS One | 10.1371/journal.pone.0019864 | 2011 | | |
| Nitric Oxide Production Inhibition and Anti-Mycobacterial Activity of Extracts and Halogenated Sesquiterpenes from the Brazilian Red Alga Laurencia Dendroidea J. Agardh. | Bia Ventura TL, da Silva Machado FL, de Araujo MH, de Souza Gestinari LM, Kaiser CR, de Assis Esteves F, Lasunskaia EB, Soares AR, Muzitano MF. | Pharmacogn Mag | 10.4103/0973-1296.172972 | 2015 | | |
| High-Throughput Screening of Natural Product and Synthetic Molecule Libraries for Antibacterial Drug Discovery. | Ayon NJ. | Metabolites | 10.3390/metabo13050625 | 2023 | | |
| Pathogenicity | Evaluation of the performance of nitrate reductase assay for rapid drug-susceptibility testing of mycobacterium tuberculosis in north India. | Gupta A, Sen MR, Mohapatra TM, Anupurba S. | J Health Popul Nutr | 10.3329/jhpn.v29i1.7563 | 2011 | |
| Phylogeny | Novel real-time simultaneous amplification and testing method to accurately and rapidly detect Mycobacterium tuberculosis complex. | Cui Z, Wang Y, Fang L, Zheng R, Huang X, Liu X, Zhang G, Rui D, Ju J, Hu Z. | J Clin Microbiol | 10.1128/jcm.05853-11 | 2012 | |
| Pathogenicity | Second-line drug susceptibility breakpoints for Mycobacterium tuberculosis using the MODS assay. | Trollip AP, Moore D, Coronel J, Caviedes L, Klages S, Victor T, Romancenco E, Crudu V, Ajbani K, Vineet VP, Rodrigues C, Jackson RL, Eisenach K, Garfein RS, Rodwell TC, Desmond E, Groessl EJ, Ganiats TG, Catanzaro A. | Int J Tuberc Lung Dis | 10.5588/ijtld.13.0229 | 2014 | |
| Pathogenicity | A Novel Small-Molecule Inhibitor of the Mycobacterium tuberculosis Demethylmenaquinone Methyltransferase MenG Is Bactericidal to Both Growing and Nutritionally Deprived Persister Cells. | Sukheja P, Kumar P, Mittal N, Li SG, Singleton E, Russo R, Perryman AL, Shrestha R, Awasthi D, Husain S, Soteropoulos P, Brukh R, Connell N, Freundlich JS, Alland D. | mBio | 10.1128/mbio.02022-16 | 2017 | |
| Phylogeny | Molecular typing of Mycobacterium abscessus based on tandem-repeat polymorphism. | Wong YL, Ong CS, Ngeow YF. | J Clin Microbiol | 10.1128/jcm.00753-12 | 2012 | |
| Increase of leishmanicidal and tubercular activities using steroids linked to aminoquinoline. | Antinarelli LM, Carmo AM, Pavan FR, Leite CQ, Da Silva AD, Coimbra ES, Salunke DB. | Org Med Chem Lett | 10.1186/2191-2858-2-16 | 2012 | | |
| Enzymology | Pharmacokinetic mismatch does not lead to emergence of isoniazid- or rifampin-resistant Mycobacterium tuberculosis but to better antimicrobial effect: a new paradigm for antituberculosis drug scheduling. | Srivastava S, Sherman C, Meek C, Leff R, Gumbo T. | Antimicrob Agents Chemother | 10.1128/aac.00269-11 | 2011 | |
| Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis. | Chauhan R, Ravi J, Datta P, Chen T, Schnappinger D, Bassler KE, Balazsi G, Gennaro ML. | Nat Commun | 10.1038/ncomms11062 | 2016 | | |
| Anthraquinones and Their Analogues from Marine-Derived Fungi: Chemistry and Biological Activities. | Hafez Ghoran S, Taktaz F, Ayatollahi SA, Kijjoa A. | Mar Drugs | 10.3390/md20080474 | 2022 | | |
| Pathogenicity | Combining computational methods for hit to lead optimization in Mycobacterium tuberculosis drug discovery. | Ekins S, Freundlich JS, Hobrath JV, Lucile White E, Reynolds RC. | Pharm Res | 10.1007/s11095-013-1172-7 | 2014 | |
| Mulinane- and Azorellane-Type Diterpenoids: A Systematic Review of Their Biosynthesis, Chemistry, and Pharmacology. | Dzul-Beh AJ, Uc-Cachon AH, Borquez J, Loyola LA, Pena-Rodriguez LM, Molina-Salinas GM. | Biomolecules | 10.3390/biom10091333 | 2020 | | |
| Cultivation | Multi-probe real-time PCR identification of common Mycobacterium species in blood culture broth. | Foongladda S, Pholwat S, Eampokalap B, Kiratisin P, Sutthent R. | J Mol Diagn | 10.2353/jmoldx.2009.080081 | 2009 | |
| Enzymology | 2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization. | Murugesan D, Ray PC, Bayliss T, Prosser GA, Harrison JR, Green K, Soares de Melo C, Feng TS, Street LJ, Chibale K, Warner DF, Mizrahi V, Epemolu O, Scullion P, Ellis L, Riley J, Shishikura Y, Ferguson L, Osuna-Cabello M, Read KD, Green SR, Lamprecht DA, Finin PM, Steyn AJC, Ioerger TR, Sacchettini J, Rhee KY, Arora K, Barry CE, Wyatt PG, Boshoff HIM. | ACS Infect Dis | 10.1021/acsinfecdis.7b00275 | 2018 | |
| Synthesis and Biological Activity of New Thiopyrano[2,3-d]thiazoles Containing a Naphthoquinone Moiety. | Atamanyuk D, Zimenkovsky B, Atamanyuk V, Nektegayev I, Lesyk R. | Sci Pharm | 10.3797/scipharm.1301-13 | 2013 | | |
| Enzymology | Evaluation of hsp65 nested PCR-restriction analysis (PRA) for diagnosing tuberculosis in a high burden country. | Macente S, Fujimura Leite CQ, Santos AC, Siqueira VL, Machado LN, Marcondes NR, Hirata MH, Hirata RD, Cardoso RF. | Biomed Res Int | 10.1155/2013/391549 | 2013 | |
| Pathogenicity | Indolyl Azaspiroketal Mannich Bases Are Potent Antimycobacterial Agents with Selective Membrane Permeabilizing Effects and in Vivo Activity. | Nyantakyi SA, Li M, Gopal P, Zimmerman M, Dartois V, Gengenbacher M, Dick T, Go ML. | J Med Chem | 10.1021/acs.jmedchem.8b00777 | 2018 | |
| Enzymology | Chlorinated coumarins from the polypore mushroom Fomitopsis officinalis and their activity against Mycobacterium tuberculosis. | Hwang CH, Jaki BU, Klein LL, Lankin DC, McAlpine JB, Napolitano JG, Fryling NA, Franzblau SG, Cho SH, Stamets PE, Wang Y, Pauli GF. | J Nat Prod | 10.1021/np400497f | 2013 | |
| Synthesis of novel indolo[3,2-c]isoquinoline derivatives bearing pyrimidine, piperazine rings and their biological evaluation and docking studies against COVID-19 virus main protease. | Verma VA, Saundane AR, Meti RS, Vennapu DR. | J Mol Struct | 10.1016/j.molstruc.2020.129829 | 2021 | | |
| Pathogenicity | Evaluation of the anti-mycobacterium tuberculosis activity and in vivo acute toxicity of Annona sylvatic. | Araujo RC, Neves FA, Formagio AS, Kassuya CA, Stefanello ME, Souza VV, Pavan FR, Croda J. | BMC Complement Altern Med | 10.1186/1472-6882-14-209 | 2014 | |
| Pathogenicity | Enhancement of the antimycobacterial activity of macrophages by ajoene. | Choi JA, Cho SN, Lim YJ, Lee J, Go D, Kim SH, Song CH. | Innate Immun | 10.1177/1753425917747975 | 2018 | |
| Metabolism | Specific interaction between Mycobacterium tuberculosis lipoprotein-derived peptides and target cells inhibits mycobacterial entry in vitro. | Ocampo M, Curtidor H, Vanegas M, Patarroyo MA, Patarroyo ME. | Chem Biol Drug Des | 10.1111/cbdd.12365 | 2014 | |
| Enzymology | Novel methodology to assess sputum smear microscopy quality in private laboratories. | Codlin AJ, Javaid M, Qazi F, Khan MS. | BMC Infect Dis | 10.1186/1471-2334-12-331 | 2012 | |
| Pathogenicity | The cyclic peptide ecumicin targeting ClpC1 is active against Mycobacterium tuberculosis in vivo. | Gao W, Kim JY, Anderson JR, Akopian T, Hong S, Jin YY, Kandror O, Kim JW, Lee IA, Lee SY, McAlpine JB, Mulugeta S, Sunoqrot S, Wang Y, Yang SH, Yoon TM, Goldberg AL, Pauli GF, Suh JW, Franzblau SG, Cho S. | Antimicrob Agents Chemother | 10.1128/aac.04054-14 | 2015 | |
| Changes in the major cell envelope components of Mycobacterium tuberculosis during in vitro growth. | Yang L, Sinha T, Carlson TK, Keiser TL, Torrelles JB, Schlesinger LS. | Glycobiology | 10.1093/glycob/cwt029 | 2013 | | |
| Enzymology | Establishing Virulence Associated Polyphosphate Kinase 2 as a drug target for Mycobacterium tuberculosis. | Singh M, Tiwari P, Arora G, Agarwal S, Kidwai S, Singh R. | Sci Rep | 10.1038/srep26900 | 2016 | |
| Antioxidant and antimicrobial activities of 7-hydroxy-calamenene-rich essential oils from Croton cajucara Benth. | Azevedo MM, Chaves FC, Almeida CA, Bizzo HR, Duarte RS, Campos-Takaki GM, Alviano CS, Alviano DS. | Molecules | 10.3390/molecules18011128 | 2013 | | |
| Pathogenicity | Evaluation of methods for rapid detection of resistance to isoniazid and rifampin in Mycobacterium tuberculosis isolates collected in the Caribbean. | Akpaka PE, Baboolal S, Clarke D, Francis L, Rastogi N. | J Clin Microbiol | 10.1128/jcm.01455-08 | 2008 | |
| Pathogenicity | Evaluation of antimicrobial and cytotoxic activities of plant extracts from southern Minas Gerais cerrado. | Chavasco JM, Prado E Feliphe BH, Cerdeira CD, Leandro FD, Coelho LF, Silva JJ, Chavasco JK, Dias AL. | Rev Inst Med Trop Sao Paulo | 10.1590/s0036-46652014000100002 | 2014 | |
| Metabolism | An NAD+ Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death. | Freire DM, Gutierrez C, Garza-Garcia A, Grabowska AD, Sala AJ, Ariyachaokun K, Panikova T, Beckham KSH, Colom A, Pogenberg V, Cianci M, Tuukkanen A, Boudehen YM, Peixoto A, Botella L, Svergun DI, Schnappinger D, Schneider TR, Genevaux P, de Carvalho LPS, Wilmanns M, Parret AHA, Neyrolles O. | Mol Cell | 10.1016/j.molcel.2019.01.028 | 2019 | |
| Screening of TB Actives for Activity against Nontuberculous Mycobacteria Delivers High Hit Rates. | Low JL, Wu ML, Aziz DB, Laleu B, Dick T. | Front Microbiol | 10.3389/fmicb.2017.01539 | 2017 | | |
| Metabolism | Increased vitamin D receptor expression from macrophages after stimulation with M. tuberculosis among persons who have recovered from extrapulmonary tuberculosis. | Fiske CT, Blackman A, Maruri F, Rebeiro PF, Huaman M, Kator J, Scott Algood HM, Sterling TR. | BMC Infect Dis | 10.1186/s12879-019-3958-7 | 2019 | |
| The rationale for using rifabutin in the treatment of MDR and XDR tuberculosis outbreaks. | Sirgel FA, Warren RM, Bottger EC, Klopper M, Victor TC, van Helden PD. | PLoS One | 10.1371/journal.pone.0059414 | 2013 | | |
| Pathogenicity | Reduced drug uptake in phenotypically resistant nutrient-starved nonreplicating Mycobacterium tuberculosis. | Sarathy J, Dartois V, Dick T, Gengenbacher M. | Antimicrob Agents Chemother | 10.1128/aac.02202-12 | 2013 | |
| Pathogenicity | Comparative Proteomics Analysis of Human Macrophages Infected with Virulent Mycobacterium bovis. | Li P, Wang R, Dong W, Hu L, Zong B, Zhang Y, Wang X, Guo A, Zhang A, Xiang Y, Chen H, Tan C. | Front Cell Infect Microbiol | 10.3389/fcimb.2017.00065 | 2017 | |
| Pathogenicity | Polymorphisms in isoniazid and prothionamide resistance genes of the Mycobacterium tuberculosis complex. | Projahn M, Koser CU, Homolka S, Summers DK, Archer JA, Niemann S. | Antimicrob Agents Chemother | 10.1128/aac.00555-11 | 2011 | |
| A novel protein kinase inhibitor IMB-YH-8 with anti-tuberculosis activity. | Xu J, Wang JX, Zhou JM, Xu CL, Huang B, Xing Y, Wang B, Luo R, Wang YC, You XF, Lu Y, Yu LY. | Sci Rep | 10.1038/s41598-017-04108-7 | 2017 | | |
| Pathogenicity | Pharmacokinetic and pharmacodynamic evaluation of AZD5847 in a mouse model of tuberculosis. | Balasubramanian V, Solapure S, Shandil R, Gaonkar S, Mahesh KN, Reddy J, Deshpande A, Bharath S, Kumar N, Wright L, Melnick D, Butler SL. | Antimicrob Agents Chemother | 10.1128/aac.00137-14 | 2014 | |
| Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis. | Tran AT, Watson EE, Pujari V, Conroy T, Dowman LJ, Giltrap AM, Pang A, Wong WR, Linington RG, Mahapatra S, Saunders J, Charman SA, West NP, Bugg TD, Tod J, Dowson CG, Roper DI, Crick DC, Britton WJ, Payne RJ. | Nat Commun | 10.1038/ncomms14414 | 2017 | | |
| Pathogenicity | A multi-antigenic MVA vaccine increases efficacy of combination chemotherapy against Mycobacterium tuberculosis. | Leung-Theung-Long S, Coupet CA, Gouanvic M, Schmitt D, Ray A, Hoffmann C, Schultz H, Tyagi S, Soni H, Converse PJ, Arias L, Kleinpeter P, Sansas B, Mdluli K, Vilaplana C, Cardona PJ, Nuermberger E, Marchand JB, Silvestre N, Inchauspe G. | PLoS One | 10.1371/journal.pone.0196815 | 2018 | |
| An Efficient Multiplex PCR-Based Assay as a Novel Tool for Accurate Inter-Serovar Discrimination of Salmonella Enteritidis, S. Pullorum/Gallinarum and S. Dublin. | Xiong D, Song L, Tao J, Zheng H, Zhou Z, Geng S, Pan Z, Jiao X. | Front Microbiol | 10.3389/fmicb.2017.00420 | 2017 | | |
| Pathogenicity | Rv2299c, a novel dendritic cell-activating antigen of Mycobacterium tuberculosis, fused-ESAT-6 subunit vaccine confers improved and durable protection against the hypervirulent strain HN878 in mice. | Choi HG, Choi S, Back YW, Paik S, Park HS, Kim WS, Kim H, Cha SB, Choi CH, Shin SJ, Kim HJ. | Oncotarget | 10.18632/oncotarget.15256 | 2017 | |
| Synthesis and antimycobacterial activity of new S-alkylisothiosemicarbazone derivatives. | Cocco MT, Congiu C, Onnis V, Pellerano ML, De Logu A. | Bioorg Med Chem | 10.1016/s0968-0896(01)00310-8 | 2002 | | |
| Pathogenicity | Direct inhibitors of InhA are active against Mycobacterium tuberculosis. | Manjunatha UH, S Rao SP, Kondreddi RR, Noble CG, Camacho LR, Tan BH, Ng SH, Ng PS, Ma NL, Lakshminarayana SB, Herve M, Barnes SW, Yu W, Kuhen K, Blasco F, Beer D, Walker JR, Tonge PJ, Glynne R, Smith PW, Diagana TT. | Sci Transl Med | 10.1126/scitranslmed.3010597 | 2015 | |
| Enzymology | 2-aminoimidazoles potentiate ß-lactam antimicrobial activity against Mycobacterium tuberculosis by reducing ß-lactamase secretion and increasing cell envelope permeability. | Jeon AB, Obregon-Henao A, Ackart DF, Podell BK, Belardinelli JM, Jackson M, Nguyen TV, Blackledge MS, Melander RJ, Melander C, Johnson BK, Abramovitch RB, Basaraba RJ. | PLoS One | 10.1371/journal.pone.0180925 | 2017 | |
| Pathogenicity | Residual Complexity Does Impact Organic Chemistry and Drug Discovery: The Case of Rufomyazine and Rufomycin. | Choules MP, Klein LL, Lankin DC, McAlpine JB, Cho SH, Cheng J, Lee H, Suh JW, Jaki BU, Franzblau SG, Pauli GF. | J Org Chem | 10.1021/acs.joc.8b00988 | 2018 | |
| Pathogenicity | Immunodeficiency and Intermittent Dosing Promote Acquired Rifamycin Monoresistance in Murine Tuberculosis. | Park SW, Tasneen R, Converse PJ, Nuermberger EL. | Antimicrob Agents Chemother | 10.1128/aac.01502-17 | 2017 | |
| Shedding light on the performance of a pyrosequencing assay for drug-resistant tuberculosis diagnosis. | Georghiou SB, Seifert M, Lin SY, Catanzaro D, Garfein RS, Jackson RL, Crudu V, Rodrigues C, Victor TC, Catanzaro A, Rodwell TC. | BMC Infect Dis | 10.1186/s12879-016-1781-y | 2016 | | |
| Metabolism | CD82 hypomethylation is essential for tuberculosis pathogenesis via regulation of RUNX1-Rab5/22. | Koh HJ, Kim YR, Kim JS, Yun JS, Kim S, Kim SY, Jang K, Yang CS. | Exp Mol Med | 10.1038/s12276-018-0091-4 | 2018 | |
| Pathogenicity | Evaluation of methods for testing the susceptibility of clinical Mycobacterium tuberculosis isolates to pyrazinamide. | Cui Z, Wang J, Lu J, Huang X, Zheng R, Hu Z. | J Clin Microbiol | 10.1128/jcm.03197-12 | 2013 | |
| Differential Identification of Mycobacterial Species Using High-Resolution Melting Analysis. | Khosravi AD, Hashemzadeh M, Hashemi Shahraki A, Teimoori A. | Front Microbiol | 10.3389/fmicb.2017.02045 | 2017 | | |
| Evaluation of a High-Intensity Green Fluorescent Protein Fluorophage Method for Drug- Resistance Diagnosis in Tuberculosis for Isoniazid, Rifampin, and Streptomycin. | Yu X, Gu Y, Jiang G, Ma Y, Zhao L, Sun Z, Jain P, O'Donnell M, Larsen M, Jacobs WR, Huang H. | Front Microbiol | 10.3389/fmicb.2016.00922 | 2016 | | |
| Enzymology | A high-throughput screen against pantothenate synthetase (PanC) identifies 3-biphenyl-4-cyanopyrrole-2-carboxylic acids as a new class of inhibitor with activity against Mycobacterium tuberculosis. | Kumar A, Casey A, Odingo J, Kesicki EA, Abrahams G, Vieth M, Masquelin T, Mizrahi V, Hipskind PA, Sherman DR, Parish T. | PLoS One | 10.1371/journal.pone.0072786 | 2013 | |
| Metabolism | Deciphering the metabolic response of Mycobacterium tuberculosis to nitrogen stress. | Williams KJ, Jenkins VA, Barton GR, Bryant WA, Krishnan N, Robertson BD. | Mol Microbiol | 10.1111/mmi.13091 | 2015 | |
| Pathogenicity | Utility of the REBA MTB-Rifa® assay for rapid detection of rifampicin resistant Mycobacterium tuberculosis. | Cho E, Shamputa IC, Kwak HK, Lee J, Lee M, Hwang S, Jeon D, Kim CT, Cho S, Via LE, Barry CE, Lee JS. | BMC Infect Dis | 10.1186/1471-2334-13-478 | 2013 | |
| Pathogenicity | Some Nigerian anti-tuberculosis ethnomedicines: a preliminary efficacy assessment. | Ibekwe NN, Nvau JB, Oladosu PO, Usman AM, Ibrahim K, Boshoff HI, Dowd CS, Orisadipe AT, Aiyelaagbe O, Adesomoju AA, Barry CE, Okogun JI, collaboration with 73 Visited Herbalists. | J Ethnopharmacol | 10.1016/j.jep.2014.05.059 | 2014 | |
| Ethnopharmacology, Antimicrobial Potency, and Phytochemistry of African Combretum and Pteleopsis Species (Combretaceae): A Review. | Silen H, Salih EYA, Mgbeahuruike EE, Fyhrqvist P. | Antibiotics (Basel) | 10.3390/antibiotics12020264 | 2023 | | |
| Synthesis, in vitro antimycobacterial and antibacterial evaluation of IMB-070593 derivatives containing a substituted benzyloxime moiety. | Wei Z, Wang J, Liu M, Li S, Sun L, Guo H, Wang B, Lu Y. | Molecules | 10.3390/molecules18043872 | 2013 | | |
| Synthesis of 1,3-thiazine derivatives and their evaluation as potential antimycobacterial agents. | Koketsu M, Tanaka K, Takenaka Y, Kwong CD, Ishihara H. | Eur J Pharm Sci | 10.1016/s0928-0987(02)00014-3 | 2002 | | |
| Metabolism | Clofazimine enhances the efficacy of BCG revaccination via stem cell-like memory T cells. | Ahmad S, Bhattacharya D, Gupta N, Rawat V, Tousif S, Van Kaer L, Das G. | PLoS Pathog | 10.1371/journal.ppat.1008356 | 2020 | |
| Improved identification of rapidly growing mycobacteria by a 16S-23S internal transcribed spacer region PCR and capillary gel electrophoresis. | Gray TJ, Kong F, Jelfs P, Sintchenko V, Chen SC. | PLoS One | 10.1371/journal.pone.0102290 | 2014 | | |
| Pathogenicity | Surveillance of pyrazinamide susceptibility among multidrug-resistant Mycobacterium tuberculosis isolates from Siriraj Hospital, Thailand. | Jonmalung J, Prammananan T, Leechawengwongs M, Chaiprasert A. | BMC Microbiol | 10.1186/1471-2180-10-223 | 2010 | |
| Therapeutic immunization against Mycobacterium tuberculosis is an effective adjunct to antibiotic treatment. | Coler RN, Bertholet S, Pine SO, Orr MT, Reese V, Windish HP, Davis C, Kahn M, Baldwin SL, Reed SG. | J Infect Dis | 10.1093/infdis/jis425 | 2013 | | |
| Rapid PCR Detection of Mycoplasma hominis, Ureaplasma urealyticum, and Ureaplasma parvum. | Cunningham SA, Mandrekar JN, Rosenblatt JE, Patel R. | Int J Bacteriol | 10.1155/2013/168742 | 2013 | | |
| Metabolism | Comparative transcriptional study of the putative mannose donor biosynthesis genes in virulent Mycobacterium tuberculosis and attenuated Mycobacterium bovis BCG strains. | Keiser TL, Azad AK, Guirado E, Bonacci R, Schlesinger LS. | Infect Immun | 10.1128/iai.05635-11 | 2011 | |
| Antimycobacterial Activities of N-Substituted-Glycinyl 1H-1,2,3-Triazolyl Oxazolidinones and Analytical Method Development and Validation for a Representative Compound. | Al-Tannak NF, Phillips OA. | Sci Pharm | 10.3390/scipharm85040034 | 2017 | | |
| The Chemical Components of Sesbania grandiflora Root and Their Antituberculosis Activity. | Hasan N, Osman H, Mohamad S, Chong WK, Awang K, Zahariluddin AS. | Pharmaceuticals (Basel) | 10.3390/ph5080882 | 2012 | | |
| Metabolism | Integration of Metabolomics and Transcriptomics Reveals a Complex Diet of Mycobacterium tuberculosis during Early Macrophage Infection. | Zimmermann M, Kogadeeva M, Gengenbacher M, McEwen G, Mollenkopf HJ, Zamboni N, Kaufmann SHE, Sauer U. | mSystems | 10.1128/msystems.00057-17 | 2017 | |
| Pathogenicity | LL-37 immunomodulatory activity during Mycobacterium tuberculosis infection in macrophages. | Torres-Juarez F, Cardenas-Vargas A, Montoya-Rosales A, Gonzalez-Curiel I, Garcia-Hernandez MH, Enciso-Moreno JA, Hancock RE, Rivas-Santiago B. | Infect Immun | 10.1128/iai.00936-15 | 2015 | |
| Pathogenicity | Thr202Ala in thyA is a marker for the Latin American Mediterranean lineage of the Mycobacterium tuberculosis complex rather than para-aminosalicylic acid resistance. | Feuerriegel S, Koser C, Trube L, Archer J, Rusch Gerdes S, Richter E, Niemann S. | Antimicrob Agents Chemother | 10.1128/aac.00738-10 | 2010 | |
| Pathogenicity | Multiplex PCR amplimer conformation analysis for rapid detection of gyrA mutations in fluoroquinolone-resistant Mycobacterium tuberculosis clinical isolates. | Cheng AF, Yew WW, Chan EW, Chin ML, Hui MM, Chan RC. | Antimicrob Agents Chemother | 10.1128/aac.48.2.596-601.2004 | 2004 | |
| Phylogeny | Identification and genotyping of Mycobacterium tuberculosis complex species by use of a SNaPshot Minisequencing-based assay. | Bouakaze C, Keyser C, de Martino SJ, Sougakoff W, Veziris N, Dabernat H, Ludes B. | J Clin Microbiol | 10.1128/jcm.02255-09 | 2010 | |
| Genetics | What Is Resistance? Impact of Phenotypic versus Molecular Drug Resistance Testing on Therapy for Multi- and Extensively Drug-Resistant Tuberculosis. | Heyckendorf J, Andres S, Koser CU, Olaru ID, Schon T, Sturegard E, Beckert P, Schleusener V, Kohl TA, Hillemann D, Moradigaravand D, Parkhill J, Peacock SJ, Niemann S, Lange C, Merker M. | Antimicrob Agents Chemother | 10.1128/aac.01550-17 | 2018 | |
| Pathogenicity | Multidrug-resistant tuberculosis not due to noncompliance but to between-patient pharmacokinetic variability. | Srivastava S, Pasipanodya JG, Meek C, Leff R, Gumbo T. | J Infect Dis | 10.1093/infdis/jir658 | 2011 | |
| Pathogenicity | Canadian multicenter laboratory study for standardized second-line antimicrobial susceptibility testing of Mycobacterium tuberculosis. | Sharma M, Thibert L, Chedore P, Shandro C, Jamieson F, Tyrrell G, Christianson S, Soualhine H, Wolfe J. | J Clin Microbiol | 10.1128/jcm.05195-11 | 2011 | |
| Enzymology | Colorimetric detection of multidrug-resistant or extensively drug-resistant tuberculosis by use of malachite green indicator dye. | Farnia P, Masjedi MR, Masjedi MR, Mohammadi F, Tabarsei P, Farnia P, Mohammadzadeh AR, Baghei P, Varahram M, Hoffner S, Velayati AA. | J Clin Microbiol | 10.1128/jcm.01435-07 | 2008 | |
| Molecular characterization of isoniazid resistance in Mycobacterium tuberculosis: identification of a novel mutation in inhA. | Leung ET, Ho PL, Yuen KY, Woo WL, Lam TH, Kao RY, Seto WH, Yam WC. | Antimicrob Agents Chemother | 10.1128/aac.50.3.1075-1078.2006 | 2006 | | |
| Aloe vera-An Extensive Review Focused on Recent Studies. | Catalano A, Ceramella J, Iacopetta D, Marra M, Conforti F, Lupi FR, Gabriele D, Borges F, Sinicropi MS. | Foods | 10.3390/foods13132155 | 2024 | | |
| Pathogenicity | N-Pyrazinoyl Substituted Amino Acids as Potential Antimycobacterial Agents-The Synthesis and Biological Evaluation of Enantiomers. | Juhas M, Kucerova L, Horacek O, Jandourek O, Kubicek V, Konecna K, Kucera R, Barta P, Janousek J, Paterova P, Kunes J, Dolezal M, Zitko J. | Molecules | 10.3390/molecules25071518 | 2020 | |
| Differential in vivo expression of mycobacterial antigens in Mycobacterium tuberculosis infected lungs and lymph node tissues. | Mustafa T, Leversen NA, Sviland L, Wiker HG. | BMC Infect Dis | 10.1186/1471-2334-14-535 | 2014 | | |
| Pathogenicity | Assessment of Mycobacterium tuberculosis pantothenate kinase vulnerability through target knockdown and mechanistically diverse inhibitors. | Reddy BK, Landge S, Ravishankar S, Patil V, Shinde V, Tantry S, Kale M, Raichurkar A, Menasinakai S, Mudugal NV, Ambady A, Ghosh A, Tunduguru R, Kaur P, Singh R, Kumar N, Bharath S, Sundaram A, Bhat J, Sambandamurthy VK, Bjorkelid C, Jones TA, Das K, Bandodkar B, Malolanarasimhan K, Mukherjee K, Ramachandran V. | Antimicrob Agents Chemother | 10.1128/aac.00140-14 | 2014 | |
| Effect of 1.5% sodium hydroxide final concentration on recovery rate of Mycobacterial Species and decontamination of other Bacterial and Fungal contaminants on sputum. | Addise D, Bitew A, Yaregal Z, Yenew B, Mollalign H, Diriba G, Kebede A. | Ethiop J Public Health Nutr | 2016 | | ||
| Association of mutation patterns in gyrA/B genes and ofloxacin resistance levels in Mycobacterium tuberculosis isolates from East China in 2009. | Cui Z, Wang J, Lu J, Huang X, Hu Z. | BMC Infect Dis | 10.1186/1471-2334-11-78 | 2011 | | |
| Pathogenicity | The pyrazinamide susceptibility breakpoint above which combination therapy fails. | Gumbo T, Chigutsa E, Pasipanodya J, Visser M, van Helden PD, Sirgel FA, McIlleron H. | J Antimicrob Chemother | 10.1093/jac/dku136 | 2014 | |
| Pathogenicity | Enhancing hit identification in Mycobacterium tuberculosis drug discovery using validated dual-event Bayesian models. | Ekins S, Reynolds RC, Franzblau SG, Wan B, Freundlich JS, Bunin BA. | PLoS One | 10.1371/journal.pone.0063240 | 2013 | |
| Enzymology | Pyrosequencing for rapid detection of extensively drug-resistant Mycobacterium tuberculosis in clinical isolates and clinical specimens. | Lin SY, Rodwell TC, Victor TC, Rider EC, Pham L, Catanzaro A, Desmond EP. | J Clin Microbiol | 10.1128/jcm.01821-13 | 2014 | |
| New Non-Toxic Semi-Synthetic Derivatives from Natural Diterpenes Displaying Anti-Tuberculosis Activity. | Matos PM, Mahoney B, Chan Y, Day DP, Cabral MM, Martins CH, Santos RA, Bastos JK, Page PC, Heleno VC. | Molecules | 10.3390/molecules201018264 | 2015 | | |
| Genetics | Population structure and circulating genotypes of drug-sensitive and drug-resistant Mycobacterium tuberculosis clinical isolates in São Paulo state, Brazil. | Martins MC, Giampaglia CM, Oliveira RS, Simonsen V, Latrilha FO, Moniz LL, Couvin D, Rastogi N, Ferrazoli L. | Infect Genet Evol | 10.1016/j.meegid.2012.10.015 | 2013 | |
| Pathogenicity | Nitrotriazole- and imidazole-based amides and sulfonamides as antitubercular agents. | Papadopoulou MV, Bloomer WD, Rosenzweig HS, Arena A, Arrieta F, Rebolledo JC, Smith DK. | Antimicrob Agents Chemother | 10.1128/aac.03644-14 | 2014 | |
| Pathogenicity | Characterization of mutations conferring extensive drug resistance to Mycobacterium tuberculosis isolates in Pakistan. | Ali A, Hasan R, Jabeen K, Jabeen N, Qadeer E, Hasan Z. | Antimicrob Agents Chemother | 10.1128/aac.05101-11 | 2011 | |
| Pathogenicity | Pyrazinamide Resistance Is Caused by Two Distinct Mechanisms: Prevention of Coenzyme A Depletion and Loss of Virulence Factor Synthesis. | Gopal P, Yee M, Sarathy J, Low JL, Sarathy JP, Kaya F, Dartois V, Gengenbacher M, Dick T. | ACS Infect Dis | 10.1021/acsinfecdis.6b00070 | 2016 | |
| Antimycobacterial Activities of Novel 5-(1H-1,2,3-Triazolyl)Methyl Oxazolidinones. | Phillips OA, Udo EE, Varghese R. | Tuberc Res Treat | 10.1155/2012/289136 | 2012 | | |
| Phylogeny | Molecular detection and identification of mycobacterium tuberculosis complex and four clinically important nontuberculous mycobacterial species in smear-negative clinical samples by the genotype mycobacteria direct test. | Bicmen C, Gunduz AT, Coskun M, Senol G, Cirak AK, Ozsoz A. | J Clin Microbiol | 10.1128/jcm.00612-11 | 2011 | |
| Genetics | A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic. | Klopper M, Heupink TH, Hill-Cawthorne G, Streicher EM, Dippenaar A, de Vos M, Abdallah AM, Limberis J, Merker M, Burns S, Niemann S, Dheda K, Posey J, Pain A, Warren RM. | BMC Med | 10.1186/s12916-019-1487-2 | 2020 | |
| Use of mycobacteriophage quantitative PCR on MGIT broths for a rapid tuberculosis antibiogram. | Foongladda S, Klayut W, Chinli R, Pholwat S, Houpt ER. | J Clin Microbiol | 10.1128/jcm.03637-13 | 2014 | | |
| Antimicrobial and Antimycobacterial Activities of Methyl Caffeate Isolated from Solanum torvum Swartz. Fruit. | Balachandran C, Duraipandiyan V, Al-Dhabi NA, Balakrishna K, Kalia NP, Rajput VS, Khan IA, Ignacimuthu S. | Indian J Microbiol | 10.1007/s12088-012-0313-8 | 2012 | | |
| Mycobacterial EST12 activates a RACK1-NLRP3-gasdermin D pyroptosis-IL-1beta immune pathway. | Qu Z, Zhou J, Zhou Y, Xie Y, Jiang Y, Wu J, Luo Z, Liu G, Yin L, Zhang XL. | Sci Adv | 10.1126/sciadv.aba4733 | 2020 | | |
| Pathogenicity | Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis. | Trivedi A, Mavi PS, Bhatt D, Kumar A. | Nat Commun | 10.1038/ncomms11392 | 2016 | |
| Metabolism | Enhanced immune response and protective effects of nano-chitosan-based DNA vaccine encoding T cell epitopes of Esat-6 and FL against Mycobacterium tuberculosis infection. | Feng G, Jiang Q, Xia M, Lu Y, Qiu W, Zhao D, Lu L, Peng G, Wang Y. | PLoS One | 10.1371/journal.pone.0061135 | 2013 | |
| Pathogenicity | Pyrazinamide resistance among South African multidrug-resistant Mycobacterium tuberculosis isolates. | Mphahlele M, Syre H, Valvatne H, Stavrum R, Mannsaker T, Muthivhi T, Weyer K, Fourie PB, Grewal HM. | J Clin Microbiol | 10.1128/jcm.00973-08 | 2008 | |
| Metabolism | Transgenic mice enriched in omega-3 fatty acids are more susceptible to pulmonary tuberculosis: impaired resistance to tuberculosis in fat-1 mice. | Bonilla DL, Fan YY, Chapkin RS, McMurray DN. | J Infect Dis | 10.1086/650344 | 2010 | |
| Pathogenicity | E-2-[3-(3,4-dichlorophenyl)-1-oxo-2-propenyl]-3-methylquinoxaline-1,4-dioxide: a lead antitubercular agent which alters mitochondrial respiration in rat liver. | Das U, Das S, Bandy B, Gorecki DK, Dimmock JR. | Eur J Med Chem | 10.1016/j.ejmech.2010.07.030 | 2010 | |
| Screening ancient tuberculosis with qPCR: challenges and opportunities. | Harkins KM, Buikstra JE, Campbell T, Bos KI, Johnson ED, Krause J, Stone AC. | Philos Trans R Soc Lond B Biol Sci | 10.1098/rstb.2013.0622 | 2015 | | |
| Pathogenicity | Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India. | Khanna A, Raj VS, Tarai B, Sood R, Pareek PK, Upadhyay DJ, Sharma P, Rattan A, Saini KS, Singh H. | Antimicrob Agents Chemother | 10.1128/aac.00661-10 | 2010 | |
| Metabolism | Mycobacterium tuberculosis Ser/Thr protein kinase B mediates an oxygen-dependent replication switch. | Ortega C, Liao R, Anderson LN, Rustad T, Ollodart AR, Wright AT, Sherman DR, Grundner C. | PLoS Biol | 10.1371/journal.pbio.1001746 | 2014 | |
| Proteome | Detection and accurate identification of Mycobacterium species by flow injection tandem mass spectrometry (FIA-MS/MS) analysis of mycolic acids. | Rafal S, Magdalena D, Karol M, Bartlomiej S, Konrad K. | Sci Rep | 10.1038/s41598-025-96867-x | 2025 | |
| Multispacer sequence typing for Mycobacterium tuberculosis genotyping. | Djelouadji Z, Arnold C, Gharbia S, Raoult D, Drancourt M. | PLoS One | 10.1371/journal.pone.0002433 | 2008 | | |
| Genotypic study of isolated resistance to isoniazid in the Mycobacterium tuberculosis complex in a Moroccan hospital. | Amri A, Benaissa E, Benlahlou Y, Bsaibis F, Maleb A, Chadli M, Elouenass M. | Access Microbiol | 10.1099/acmi.0.000928.v5 | 2025 | | |
| Emergence of phenotypic and genotypic antimicrobial resistance in Mycobacterium tuberculosis. | Kloprogge F, Ortiz Canseco J, Phee L, Sadouki Z, Kipper K, Witney AA, Stoker N, McHugh TD. | Sci Rep | 10.1038/s41598-022-25827-6 | 2022 | | |
| Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates. | White AD, Tran AC, Sibley L, Sarfas C, Morrison AL, Lawrence S, Dennis M, Clark S, Zadi S, Lanni F, Rayner E, Copland A, Hart P, Diogo GR, Paul MJ, Kim M, Gleeson F, Salguero FJ, Singh M, Stehr M, Cutting SM, Basile JI, Rottenberg ME, Williams A, Sharpe SA, Reljic R. | Front Immunol | 10.3389/fimmu.2023.1246826 | 2023 | | |
| Molecular mechanism of interaction of Mycobacterium tuberculosis with host macrophages under high glucose conditions. | Kundu J, Verma A, Verma I, Bhadada SK, Sharma S. | Biochem Biophys Rep | 10.1016/j.bbrep.2021.100997 | 2021 | | |
| Enzymology | Determination of the Pharmacokinetics and Pharmacodynamics of Isoniazid, Rifampicin, Pyrazinamide and Ethambutol in a Cross-Over Cynomolgus Macaque Model of Mycobacterium tuberculosis Infection. | Sibley L, White AD, Sarfas C, Gullick J, Gleeson F, Lanni F, Clark S, Rayner E, Ferrer-Bazaga S, Ortega-Muro F, Alameda L, Rullas J, Sousa V, Martinez M, Angulo-Barturen I, Garcia A, Vaquero JJ, Pertinez HE, Davies G, Dennis M, Williams A, Sharpe S. | Pharmaceutics | 10.3390/pharmaceutics14122666 | 2022 | |
| Phylogeny | Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts. | Orgeur M, Frigui W, Pawlik A, Clark S, Williams A, Ates LS, Ma L, Bouchier C, Parkhill J, Brodin P, Brosch R. | Microb Genom | 10.1099/mgen.0.000505 | 2021 | |
| Immunological aspects of host-pathogen crosstalk in the co-pathogenesis of diabetes and latent tuberculosis. | Verma A, Kaur M, Luthra P, Singh L, Aggarwal D, Verma I, Radotra BD, Bhadada SK, Sharma S. | Front Cell Infect Microbiol | 10.3389/fcimb.2022.957512 | 2022 | | |
| Implications of drug-induced phenotypical resistance: Is isoniazid radicalizing M. tuberculosis? | Hammond R, Kloprogge F, Pasqua OD, Gillespie SH. | Front Antibiot | 10.3389/frabi.2022.928365 | 2022 | | |
| Pathogenicity | The effect of growth rate on pyrazinamide activity in Mycobacterium tuberculosis - insights for early bactericidal activity? | Pullan ST, Allnutt JC, Devine R, Hatch KA, Jeeves RE, Hendon-Dunn CL, Marsh PD, Bacon J. | BMC Infect Dis | 10.1186/s12879-016-1533-z | 2016 | |
| Pathogenicity | Assessment of vaccine testing at three laboratories using the guinea pig model of tuberculosis. | Grover A, Troudt J, Arnett K, Izzo L, Lucas M, Strain K, McFarland C, Hall Y, McMurray D, Williams A, Dobos K, Izzo A. | Tuberculosis (Edinb) | 10.1016/j.tube.2011.09.003 | 2012 | |
| Pathogenicity | Mycobacterium tuberculosis DNA repair in response to subinhibitory concentrations of ciprofloxacin. | O'Sullivan DM, Hinds J, Butcher PD, Gillespie SH, McHugh TD. | J Antimicrob Chemother | 10.1093/jac/dkn387 | 2008 | |
| Pathogenicity | Mycobactericidal activity of selected disinfectants using a quantitative suspension test. | Griffiths PA, Babb JR, Fraise AP. | J Hosp Infect | 10.1016/s0195-6701(99)90048-8 | 1999 | |
| Metabolism | Isolation, identification and characterization of Paenibacillus polymyxa CR1 with potentials for biopesticide, biofertilization, biomass degradation and biofuel production. | Weselowski B, Nathoo N, Eastman AW, MacDonald J, Yuan ZC. | BMC Microbiol | 10.1186/s12866-016-0860-y | 2016 | |
| Genomic fingerprinting of Mycobacterium bovis from cattle by restriction fragment length polymorphism analysis. | Skuce RA, Brittain D, Hughes MS, Beck LA, Neill SD. | J Clin Microbiol | 10.1128/jcm.32.10.2387-2392.1994 | 1994 | | |
| Demonstration of homology between IS6110 of Mycobacterium tuberculosis and DNAs of other Mycobacterium spp.? | Kent L, McHugh TD, Billington O, Dale JW, Gillespie SH. | J Clin Microbiol | 10.1128/jcm.33.9.2290-2293.1995 | 1995 | | |
| Enzymology | Detection of Mycobacterium tuberculosis group organisms in human and mouse joint tissue by reverse transcriptase PCR: prevalence in diseased synovial tissue suggests lack of specific association with rheumatoid arthritis. | Kempsell KE, Cox CJ, McColm AA, Bagshaw JA, Reece R, Veale DJ, Emery P, Isaacs JD, Gaston JS, Crowe JS. | Infect Immun | 10.1128/iai.69.3.1821-1831.2001 | 2001 | |
| Phylogeny | Assessment of genetic markers for species differentiation within the Mycobacterium tuberculosis complex. | Liebana E, Aranaz A, Francis B, Cousins D. | J Clin Microbiol | 10.1128/jcm.34.4.933-938.1996 | 1996 | |
| Identification of a Mycobacterium bovis BCG auxotrophic mutant that protects guinea pigs against M. bovis and hematogenous spread of Mycobacterium tuberculosis without sensitization to tuberculin. | Chambers MA, Williams A, Gavier-Widen D, Whelan A, Hall G, Marsh PD, Bloom BR, Jacobs WR, Hewinson RG. | Infect Immun | 10.1128/iai.68.12.7094-7099.2000 | 2000 | | |
| Pathogenicity | Signature gene expression profiles discriminate between isoniazid-, thiolactomycin-, and triclosan-treated Mycobacterium tuberculosis. | Betts JC, McLaren A, Lennon MG, Kelly FM, Lukey PT, Blakemore SJ, Duncan K. | Antimicrob Agents Chemother | 10.1128/aac.47.9.2903-2913.2003 | 2003 | |
| Metabolism | Expression and characterization of the Mycobacterium tuberculosis serine/threonine protein kinase PknB. | Av-Gay Y, Jamil S, Drews SJ. | Infect Immun | 10.1128/iai.67.11.5676-5682.1999 | 1999 | |
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| Expression of a gene for a porin-like protein of the OmpA family from Mycobacterium tuberculosis H37Rv. | Senaratne RH, Mobasheri H, Papavinasasundaram KG, Jenner P, Lea EJ, Draper P. | J Bacteriol | 10.1128/jb.180.14.3541-3547.1998 | 1998 | | |
| Pathogenicity | In vitro activities of two glycylcyclines. | Wise R, Andrews JM. | Antimicrob Agents Chemother | 10.1128/aac.38.5.1096 | 1994 | |
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How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive170314.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
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