Capnocytophaga sputigena 4 is an anaerobe, mesophilic, Gram-negative prokaryote that was isolated from periodontal lesions.
Gram-negative rod-shaped anaerobe mesophilic genome sequence 16S sequence| @ref 20215 |
|
|
| Domain Pseudomonadati |
| Phylum Bacteroidota |
| Class Flavobacteriia |
| Order Flavobacteriales |
| Family Flavobacteriaceae |
| Genus Capnocytophaga |
| Species Capnocytophaga sputigena |
| Full scientific name Capnocytophaga sputigena Leadbetter et al. 1982 |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 3090 | CAPNOCYTOPHAGA MEDIUM (DSMZ Medium 340) | Medium recipe at MediaDive | Name: CAPNOCYTOPHAGA MEDIUM (DSMZ Medium 340) Composition: Trypticase 17.0 g/l KNO3 3.0 g/l NaCl 3.0 g/l Glucose 3.0 g/l Yeast extract 3.0 g/l Haemin 0.003 g/l Distilled water | ||
| 37924 | MEDIUM 20 - for Anaerobic bacteria | Agar (15.000 g);Glucose (5.000 g);Yeast extract (20.000 g);Tryptone (30.000 g);Cysteine hydrochloride (0.500 g);distilled water (1000.000 ml);Hemin solution -M00149 (25.000 ml) | |||
| 3090 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | Medium recipe at MediaDive | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base | ||
| 123285 | CIP Medium 45 | Medium recipe at CIP | |||
| 123285 | CIP Medium 20 | Medium recipe at CIP |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68377 | 15824 ChEBI | D-fructose | + | builds acid from | from API NH |
| 68377 | 17634 ChEBI | D-glucose | + | builds acid from | from API NH |
| 68377 | 17306 ChEBI | maltose | + | builds acid from | from API NH |
| 123285 | 17632 ChEBI | nitrate | + | reduction | |
| 123285 | 16301 ChEBI | nitrite | - | reduction | |
| 68377 | 18257 ChEBI | ornithine | - | degradation | from API NH |
| 68377 | 27897 ChEBI | tryptophan | - | energy source | from API NH |
| 68377 | 16199 ChEBI | urea | - | hydrolysis | from API NH |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 68377 | alkaline phosphatase | + | 3.1.3.1 | from API NH |
| 68382 | alkaline phosphatase | + | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | - | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 68377 | beta-galactosidase | + | 3.2.1.23 | from API NH |
| 68382 | beta-glucosidase | - | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 123285 | catalase | + | 1.11.1.6 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 68382 | esterase (C 4) | - | from API zym | |
| 68382 | esterase lipase (C 8) | + | from API zym | |
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 68382 | lipase (C 14) | - | from API zym | |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | - | from API zym | |
| 68377 | ornithine decarboxylase | - | 4.1.1.17 | from API NH |
| 123285 | oxidase | - | ||
| 68377 | proline-arylamidase | + | 3.4.11.5 | from API NH |
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 68377 | tryptophan deaminase | - | 4.1.99.1 | from API NH |
| 123285 | urease | + | 3.5.1.5 | |
| 68377 | urease | - | 3.5.1.5 | from API NH |
| 68382 | valine arylamidase | - | from API zym |
| Cat1 | Cat2 | Cat3 | |
|---|---|---|---|
| #Host Body-Site | #Oral cavity and airways | - | |
| #Host Body-Site | #Other | #Wound |
Global distribution of 16S sequence NR_026095 (>99% sequence identity) for Capnocytophaga sputigena subclade from Microbeatlas ![]()
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 66792 | 48903_C01 assembly for Capnocytophaga sputigena NCTC11653 | contig | 1019 | 77.41 | ||||
| 67770 | ASM17367v1 assembly for Capnocytophaga sputigena ATCC 33612 | contig | 553177 | 65.77 |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 20218 | Capnocytophaga sputigena gene for 16S ribosomal RNA, partial sequence, strain: JCM 12967 | AB671762 | 1477 | 1019 | ||
| 20218 | Capnocytophaga sputigena 16S ribosomal RNA | L14636 | 1465 | 1019 | ||
| 20218 | C.sputigena gene for 16S rRNA | X67609 | 1489 | 553177 | ||
| 3090 | Capnocytophaga sputigena ATCC 33612 16S ribosomal RNA, partial sequence | NR_026095 | 1489 | 553177 |
| @ref | Trait | Model | Prediction | Confidence in % | In training data |
|---|---|---|---|---|---|
| 125439 | oxygen_tolerance | BacteriaNetⓘ | facultative anaerobe | 66.30 | no |
| 125439 | gram_stain | BacteriaNetⓘ | negative | 99.20 | no |
| 125439 | motility | BacteriaNetⓘ | no | 64.10 | no |
| 125439 | spore_formation | BacteriaNetⓘ | no | 99.70 | no |
| @ref | Trait | Model | Prediction | Confidence in % | In training data |
|---|---|---|---|---|---|
| 125438 | gram-positive | gram-positiveⓘ | no | 96.67 | no |
| 125438 | anaerobic | anaerobicⓘ | no | 87.08 | no |
| 125438 | spore-forming | spore-formingⓘ | no | 93.71 | no |
| 125438 | aerobic | aerobicⓘ | no | 75.06 | no |
| 125438 | thermophilic | thermophileⓘ | no | 96.00 | yes |
| 125438 | flagellated | motile2+ⓘ | no | 92.00 | no |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Evaluation of microbiota associated with Herpesviruses in active sites of generalized aggressive periodontitis. | Passariello C, Gigola P, Testarelli L, Puttini M, Schippa S, Petti S. | Ann Stomatol (Roma) | 10.11138/ads/2017.8.2.071 | 2017 | ||
| Antimicrobial Activity of Methylene Blue Associated with Photodynamic Therapy: In Vitro Study in Multi-Species Oral Biofilm. | Bueno-Silva B, Parma-Garcia J, Frigo L, Suarez LJ, Macedo TT, Uyeda FH, Melo MARDC, Sacco R, Mourao CF, Feres M, Shibli JA, Figueiredo LC. | Pathogens | 10.3390/pathogens13040342 | 2024 | ||
| Pathogenicity | Antibacterial Activity of a Bioactive Tooth-Coating Material Containing Surface Pre-Reacted Glass in a Complex Multispecies Subgingival Biofilm. | Tanaka CJ, Rodrigues JA, Pingueiro JMS, Macedo TT, Feres M, Shibli JA, Bueno-Silva B. | Pharmaceutics | 10.3390/pharmaceutics15061727 | 2023 | |
| Evaluation of the Microbial Profile on the Polydioxanone Membrane and the Collagen Membrane Exposed to Multi-Species Subgingival Biofilm: An In Vitro Study. | Cintra Moreira MV, Figueiredo LC, da Cunha Melo MAR, Uyeda FH, da Silva LDA, Macedo TT, Sacco R, Mourao CF, Shibli JA, Bueno-Silva B. | Membranes (Basel) | 10.3390/membranes13120907 | 2023 | ||
| Lactobacillus acidophilus impairs the establishment of pathogens in a subgingival multispecies biofilm. | Bueno MR, Dudu-Silva G, Macedo TT, Gomes APAP, Rodrigues Oliveira Braga A, Aguiar Silva LD, Bueno-Silva B. | Front Dent Med | 10.3389/fdmed.2023.1212773 | 2023 | ||
| Metabolism | In vitro Increased Respiratory Activity of Selected Oral Bacteria May Explain Competitive and Collaborative Interactions in the Oral Microbiome. | Hernandez-Sanabria E, Slomka V, Herrero ER, Kerckhof FM, Zaidel L, Teughels W, Boon N. | Front Cell Infect Microbiol | 10.3389/fcimb.2017.00235 | 2017 | |
| Propolis, Aloe Vera, Green Tea, Cranberry, Calendula, Myrrha and Salvia Properties against Periodontal Microorganisms. | Figueiredo LC, Freitas Figueiredo N, da Cruz DF, Baccelli GT, Sarachini GE, Bueno MR, Feres M, Bueno-Silva B. | Microorganisms | 10.3390/microorganisms10112172 | 2022 | ||
| Genetics | Genome sequence of the halotolerant bacterium Imtechella halotolerans K1T. | Kumar S, Vikram S, Subramanian S, Raghava GP, Pinnaka AK. | J Bacteriol | 10.1128/jb.00506-12 | 2012 | |
| Pathogenicity | Metabolomics evaluation of the impact of smokeless tobacco exposure on the oral bacterium Capnocytophaga sputigena. | Sun J, Jin J, Beger RD, Cerniglia CE, Yang M, Chen H. | Toxicol In Vitro | 10.1016/j.tiv.2016.07.020 | 2016 | |
| Brazilian Red Propolis Is as Effective as Amoxicillin in Controlling Red-Complex of Multispecies Subgingival Mature Biofilm In Vitro. | de Figueiredo KA, da Silva HDP, Miranda SLF, Goncalves FJDS, de Sousa AP, de Figueiredo LC, Feres M, Bueno-Silva B. | Antibiotics (Basel) | 10.3390/antibiotics9080432 | 2020 | ||
| Metabolic activity of hydro-carbon-oxo-borate on a multispecies subgingival periodontal biofilm: a short communication. | Shibli JA, Rocha TF, Coelho F, de Oliveira Capote TS, Saska S, Melo MA, Pingueiro JMS, de Faveri M, Bueno-Silva B. | Clin Oral Investig | 10.1007/s00784-021-03900-0 | 2021 | ||
| Analysing the Relationship between Nutrition and the Microbial Composition of the Oral Biofilm-Insights from the Analysis of Individual Variability. | Vach K, Al-Ahmad A, Anderson A, Woelber JP, Karygianni L, Wittmer A, Hellwig E. | Antibiotics (Basel) | 10.3390/antibiotics9080479 | 2020 | ||
| Pathogenicity | Effect of smokeless tobacco products on human oral bacteria growth and viability. | Liu M, Jin J, Pan H, Feng J, Cerniglia CE, Yang M, Chen H. | Anaerobe | 10.1016/j.anaerobe.2016.10.006 | 2016 | |
| Modulation of Neutrophil Extracellular Trap and Reactive Oxygen Species Release by Periodontal Bacteria. | Hirschfeld J, White PC, Milward MR, Cooper PR, Chapple ILC. | Infect Immun | 10.1128/iai.00297-17 | 2017 | ||
| Nucleotide sequences of 16S rRNA encoding genes from Capnocytophaga ochracea ATCC 33596, Capnocytophaga sputigena ATCC 33612 and Capnocytophaga gingivalis ATCC 33624. | Conrads G, Lutticken R. | Nucleic Acids Res | 10.1093/nar/20.21.5847 | 1992 | ||
| Filifactor alocis--involvement in periodontal biofilms. | Schlafer S, Riep B, Griffen AL, Petrich A, Hubner J, Berning M, Friedmann A, Gobel UB, Moter A. | BMC Microbiol | 10.1186/1471-2180-10-66 | 2010 | ||
| An in vitro biofilm model of subgingival plaque. | Walker C, Sedlacek MJ. | Oral Microbiol Immunol | 10.1111/j.1399-302x.2007.00336.x | 2007 | ||
| Transcriptome | Gene expression of bacterial collagenolytic proteases in root caries. | Dame-Teixeira N, Parolo CCF, Maltz M, Rup AG, Devine DA, Do T. | J Oral Microbiol | 10.1080/20002297.2018.1424475 | 2018 | |
| Phylogeny | Only a subset of C. canimorsus strains is dangerous for humans. | Renzi F, Dol M, Raymackers A, Manfredi P, Cornelis GR. | Emerg Microbes Infect | 10.1038/emi.2015.48 | 2015 | |
| Effects of azithromycin, metronidazole, amoxicillin, and metronidazole plus amoxicillin on an in vitro polymicrobial subgingival biofilm model. | Soares GM, Teles F, Starr JR, Feres M, Patel M, Martin L, Teles R. | Antimicrob Agents Chemother | 10.1128/aac.04974-14 | 2015 | ||
| The vaginal microflora in relation to gingivitis. | Persson R, Hitti J, Verhelst R, Vaneechoutte M, Persson R, Hirschi R, Weibel M, Rothen M, Temmerman M, Paul K, Eschenbach D. | BMC Infect Dis | 10.1186/1471-2334-9-6 | 2009 | ||
| Metabolism | Periodontal pathogens produce quorum sensing signal molecules. | Frias J, Olle E, Alsina M. | Infect Immun | 10.1128/iai.69.5.3431-3434.2001 | 2001 | |
| Phylogeny | Are putative periodontal pathogens reliable diagnostic markers? | Riep B, Edesi-Neuss L, Claessen F, Skarabis H, Ehmke B, Flemmig TF, Bernimoulin JP, Gobel UB, Moter A. | J Clin Microbiol | 10.1128/jcm.01387-08 | 2009 | |
| Pathogenicity | A lactotransferrin single nucleotide polymorphism demonstrates biological activity that can reduce susceptibility to caries. | Fine DH, Toruner GA, Velliyagounder K, Sampathkumar V, Godboley D, Furgang D. | Infect Immun | 10.1128/iai.01063-12 | 2013 | |
| Enzymology | Enzymatic and antigenic characterization of immunoglobulin A1 proteases from Bacteroides and Capnocytophaga spp. | Frandsen EV, Reinholdt J, Kilian M. | Infect Immun | 10.1128/iai.55.3.631-638.1987 | 1987 | |
| Intergeneric coaggregation of oral Treponema spp. with Fusobacterium spp. and intrageneric coaggregation among Fusobacterium spp. | Kolenbrander PE, Parrish KD, Andersen RN, Greenberg EP. | Infect Immun | 10.1128/iai.63.12.4584-4588.1995 | 1995 | ||
| Intrageneric coaggregation among strains of human oral bacteria: potential role in primary colonization of the tooth surface. | Kolenbrander PE, Andersen RN, Moore LV. | Appl Environ Microbiol | 10.1128/aem.56.12.3890-3894.1990 | 1990 | ||
| Enzymology | Sialidase (neuraminidase) activity among gram-negative anaerobic and capnophilic bacteria. | Moncla BJ, Braham P, Hillier SL. | J Clin Microbiol | 10.1128/jcm.28.3.422-425.1990 | 1990 | |
| Enzymology | Use of synthetic oligonucleotide DNA probes for identification and direct detection of Bacteroides forsythus in plaque samples. | Moncla BJ, Motley ST, Braham P, Ewing L, Adams TH, Vermeulen NM. | J Clin Microbiol | 10.1128/jcm.29.10.2158-2162.1991 | 1991 | |
| Growth of Porphyromonas gingivalis, Treponema denticola, T. pectinovorum, T. socranskii, and T. vincentii in a chemically defined medium. | Wyss C. | J Clin Microbiol | 10.1128/jcm.30.9.2225-2229.1992 | 1992 | ||
| Coaggregation of Fusobacterium nucleatum, Selenomonas flueggei, Selenomonas infelix, Selenomonas noxia, and Selenomonas sputigena with strains from 11 genera of oral bacteria. | Kolenbrander PE, Andersen RN, Moore LV. | Infect Immun | 10.1128/iai.57.10.3194-3203.1989 | 1989 | ||
| Coaggregation properties of human oral Veillonella spp.: relationship to colonization site and oral ecology. | Hughes CV, Kolenbrander PE, Andersen RN, Moore LV. | Appl Environ Microbiol | 10.1128/aem.54.8.1957-1963.1988 | 1988 | ||
| Compilation of small ribosomal subunit RNA structures. | Neefs JM, Van de Peer Y, De Rijk P, Chapelle S, De Wachter R. | Nucleic Acids Res | 10.1093/nar/21.13.3025 | 1993 | ||
| Bacteriology of experimental gingivitis in young adult humans. | Moore WE, Holdeman LV, Smibert RM, Good IJ, Burmeister JA, Palcanis KG, Ranney RR. | Infect Immun | 10.1128/iai.38.2.651-667.1982 | 1982 | ||
| Pathogenicity | Role of DNA gyrase and topoisomerase IV mutations in fluoroquinolone resistance of Capnocytophaga spp. clinical isolates and laboratory mutants. | Ehrmann E, Jolivet-Gougeon A, Bonnaure-Mallet M, Fosse T | J Antimicrob Chemother | 10.1093/jac/dkx119 | 2017 |
| #3090 | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 7273 |
| #20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 ) |
| #20218 | Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 ) |
| #37924 | ; Curators of the CIP; |
| #45230 | Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 9714 |
| #66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) . |
| #67770 | Japan Collection of Microorganism (JCM) ; Curators of the JCM; |
| #68377 | Automatically annotated from API NH . |
| #68382 | Automatically annotated from API zym . |
| #69479 | João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta . |
| #123285 | Collection of Institut Pasteur ; Curators of the CIP; CIP 110086 |
| #125438 | Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 ) |
| #125439 | Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 . |
| #126262 | A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 ) |
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