Name: Bordetella pertussis 18323
Creator: BacDive
License: http://creativecommons.org/licenses/by-nc/4.0/

Strain identifier

BacDive ID: 374

Type strain:

Species: Bordetella pertussis

Strain Designation: 18323

Culture col. no.: DSM 5571, ATCC 9797, CCUG 30873, CCUG 17764, NCTC 10739, LMG 14455, CIP 63.1

Strain history: <- ATCC <- M. Pittman; 18323 <- P. Kendrick

NCBI tax ID(s): 520 (species)

Other strains from Bordetella pertussis

Section

Bordetella pertussis 18323 is a mesophilic, rod-shaped bacterium of the family Alcaligenaceae.

rod-shaped
mesophilic
16S sequence
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	25-08-2022 (DD-MM-YYYY)
	Domain	Bacteria
	Phylum	Pseudomonadota
	Class	Betaproteobacteria
	Order	Burkholderiales
	Family	Alcaligenaceae
	Genus	Bordetella
	Species	Bordetella pertussis
	Full Scientific Name (PNU)	Bordetella pertussis (Bergey et al. 1923) Moreno-López 1952 (Approved Lists 1980)

Synonym

Hemophilus pertussis

Information on morphological and physiological properties Morphology

[Ref.: #22906]	Cell length	1.4 µm
[Ref.: #22906]	Cell width	0.8 µm
[Ref.: #22906]	Cell shape	rod-shaped
[Ref.: #22906]	Flagellum arrangement	monotrichous

[Ref.: #2227]	Type of hemolysis	alpha
[Ref.: #2227]	Incubation period	1-2 days

Information on culture and growth conditions Culture and growth conditions

[Ref.: #2227]

Culture medium

BORDET-GENGOU-MEDIUM (DIFCO) (DSMZ Medium 438)

[Ref.: #2227]

Culture medium growth

[Ref.: #2227]

Culture medium link

Medium recipe at MediaDive

[Ref.: #2227]

Culture medium composition

expand / minimize

[Ref.: #39796]

Culture medium

MEDIUM 440 - for Bordetella

[Ref.: #39796]

Culture medium growth

[Ref.: #39796]

Culture medium composition

expand / minimize

[Ref.: #2227]

Culture medium

COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)

[Ref.: #2227]

Culture medium growth

[Ref.: #2227]

Culture medium link

Medium recipe at MediaDive

[Ref.: #2227]

Culture medium composition

expand / minimize

		Temperature
[Ref.: #2227]	growth	37 °C
[Ref.: #39796]	growth	37 °C
[Ref.: #50311]	growth	37 °C

[Ref.: #2227]	Temperature range	mesophilic
[Ref.: #39796]	Temperature range	mesophilic
[Ref.: #50311]	Temperature range	mesophilic

Information on physiology and metabolism Physiology and metabolism

	Metabolite	Utilization activity	Kind of utilization tested
[Ref.: #22905]	2-dehydro-D-gluconate ChEBI	-	growth
[Ref.: #22906]	3-hydroxybutyrate ChEBI	+	growth
[Ref.: #22905]	5-dehydro-D-gluconate ChEBI	-	growth
[Ref.: #22905]	5-oxoproline ChEBI	-	other
[Ref.: #22906]	acetate ChEBI	-	growth
[Ref.: #22905]	adipate ChEBI	-	growth
[Ref.: #22906]	adipate ChEBI	-	growth
[Ref.: #22906]	arabinose ChEBI	-	growth
[Ref.: #22905]	arginine ChEBI	+	other
[Ref.: #22906]	citrate ChEBI	+	growth
[Ref.: #22905]	cysteine ChEBI	-	other
[Ref.: #68377]	D-fructose ChEBI	-	builds acid from	* from API NH
[Ref.: #22905]	D-gluconate ChEBI	-	growth
[Ref.: #22905]	D-glucose ChEBI	-	growth
[Ref.: #22906]	D-glucose ChEBI	+	growth
[Ref.: #68377]	D-glucose ChEBI	-	builds acid from	* from API NH
[Ref.: #22906]	D-mannitol ChEBI	-	growth
[Ref.: #22906]	D-ribose ChEBI	-	growth
[Ref.: #22906]	D-sorbitol ChEBI	-	growth
[Ref.: #22905]	D-xylose ChEBI	-	growth
[Ref.: #22905]	decanoate ChEBI	-	growth
[Ref.: #22906]	decanoate ChEBI	-	growth
[Ref.: #22905]	esculin ChEBI	-	growth
[Ref.: #22906]	gelatin ChEBI	-	growth
[Ref.: #22906]	gluconate ChEBI	+/-	growth
[Ref.: #22905]	glucose ChEBI	-	fermentation
[Ref.: #22906]	glucose ChEBI	-	builds acid from
[Ref.: #22905]	glutamyl-glutamic acid ChEBI	+	other
[Ref.: #22906]	glycogen ChEBI	-	growth
[Ref.: #22906]	itaconate ChEBI	-	growth
[Ref.: #22906]	L-alanine ChEBI	-	growth
[Ref.: #22906]	L-arabinose ChEBI	-	growth
[Ref.: #22905]	L-aspartate ChEBI	+	other
[Ref.: #22906]	L-fucose ChEBI	-	growth
[Ref.: #22906]	L-histidine ChEBI	+	growth
[Ref.: #22905]	L-malate ChEBI	-	growth
[Ref.: #22906]	L-proline ChEBI	+	growth
[Ref.: #22906]	L-rhamnose ChEBI	-	growth
[Ref.: #22906]	L-serine ChEBI	+	growth
[Ref.: #22906]	lactate ChEBI	-	growth
[Ref.: #22905]	leucylglycine ChEBI	+	other
[Ref.: #22906]	malate ChEBI	+	growth
[Ref.: #22906]	malonate ChEBI	-	growth
[Ref.: #22906]	maltose ChEBI	-	growth
[Ref.: #68377]	maltose ChEBI	-	builds acid from	* from API NH
[Ref.: #22906]	mannose ChEBI	-	growth
[Ref.: #22906]	melibiose ChEBI	-	growth
[Ref.: #22906]	myo-inositol ChEBI	-	growth
[Ref.: #22906]	N-acetyl-D-glucosamine ChEBI	-	growth
[Ref.: #22905]	nitrate ChEBI	-	reduction
[Ref.: #22906]	O-nitrophenyl-beta-D-galactopyranosid	-	growth
[Ref.: #22905]	phenylacetate ChEBI	-	growth
[Ref.: #22906]	phenylacetate ChEBI	-	growth
[Ref.: #22905]	phenylalanine ChEBI	+	other
[Ref.: #22906]	propionate ChEBI	+	growth
[Ref.: #22906]	salicin ChEBI	-	growth
[Ref.: #22905]	serine ChEBI	+	other
[Ref.: #22906]	suberate ChEBI	+	growth
[Ref.: #22906]	sucrose ChEBI	-	growth
[Ref.: #68377]	tryptophan ChEBI	-	energy source	* from API NH
[Ref.: #22905]	tyrosine ChEBI	+	other
[Ref.: #68377]	urea ChEBI	-	hydrolysis	* from API NH
[Ref.: #22906]	valerate ChEBI	+	growth
[Ref.: #22905]	valine ChEBI	-	other
	Only first 10 entries are displayed. Click here to see all.

	Metabolite production	Metabolite
[Ref.: #22906]		hydrogen sulfide ChEBI
[Ref.: #68377]		indole ChEBI	* from API NH

	Physiological tests	Metabolite	Indole test
[Ref.: #68377]		indole ChEBI	-	* from API NH

	Enzyme	Enzyme activity	EC number
[Ref.: #22906]	acid phosphatase	-	3.1.3.2
[Ref.: #22906]	alkaline phosphatase	-	3.1.3.1
[Ref.: #68377]	alkaline phosphatase	-	3.1.3.1	* from API NH
[Ref.: #22906]	alpha-galactosidase	-	3.2.1.22
[Ref.: #22906]	arginine dihydrolase	+	3.5.3.6
[Ref.: #68377]	beta-galactosidase	-	3.2.1.23	* from API NH
[Ref.: #68377]	beta-lactamase	-	3.5.2.6	* from API NH
[Ref.: #2227]	catalase	+	1.11.1.6
[Ref.: #22906]	cystine arylamidase	-	3.4.11.3
[Ref.: #2227]	cytochrome-c oxidase	+	1.9.3.1
[Ref.: #22906]	esterase Lipase (C 8)	+/-
[Ref.: #22906]	leucine arylamidase	+/-	3.4.11.1
[Ref.: #68377]	lipase	-		* from API NH
[Ref.: #22905]	lysine decarboxylase	-	4.1.1.18
[Ref.: #22906]	naphthol-AS-BI-phosphohydrolase	+/-
[Ref.: #68377]	tryptophan deaminase	-	4.1.99.1	* from API NH
[Ref.: #22905]	urease	-	3.5.1.5
[Ref.: #68377]	urease	-	3.5.1.5	* from API NH
	Only first 10 entries are displayed. Click here to see all.

API® NH:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Penicillinase productionPEN	Acid from D-glucoseGLU	Acid from D-fructoseFRU	Acid from maltoseMAL	Acid from sucroseSAC	Ornithine decarboxylaseODC	Urease/urea hydrolysisURE	LipaseLIP	Alkaline phosphatasePAL	beta-Galactosidasebeta GAL	Proline arylamidaseProA	gamma-Glutamyl transferaseGGT	Indole productionIND
[Ref.: #2227]	4055	-	-	-	-	-	-	-	-	-	-	-	+	-
[Ref.: #2227]	3992	-	-	-	-	-	-	-	-	-	-	-	+	-
[Ref.: #2227]	3962	-	-	-	-	-	-	-	-	-	-	-	+	-
[Ref.: #2227]	3961	-	-	-	-	-	-	-	-	-	-	-	+	-
[Ref.: #2227]	3960	-	-	-	-	-	-	-	-	-	-	-	+	-
[Ref.: #2227]	3959	-	-	-	-	-	+/-	-	-	-	-	-	+	-
[Ref.: #2227]	3958	-	-	-	-	-	-	-	-	-	-	-	+	-
[Ref.: #2227]	4087	-	-	-	-	-	-	-	-	-	-	+	-	-
[Ref.: #2227]	4088	-	-	-	-	-	-	-	-	-	-	+	-	-
[Ref.: #2227]	4089	-	-	-	-	-	-	-	-	-	-	+	-	-
[Ref.: #2227]	4090	-	-	-	-	-	-	-	-	-	-	+	-	-
[Ref.: #2227]	4091	-	-	-	-	+/-	-	-	-	-	-	+	-	-
[Ref.: #2227]	4352	-	-	-	-	-	-	-	-	-	-	-	+	-

Information on possible application of the strain and its possible interaction with e.g. potential hosts Safety information

[Ref.: #2227]

Biosafety level

Risk group (German classification)
According to TRBA 466

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

16S Sequence information:

	Sequence accession description	Seq. accession number	Sequence length (bp)	Sequence database	Associated NCBI tax ID
[Ref.: #2227]	Bordetella pertussis ATCC 9797 16S rRNA, partial sequence	U04950	1464	ENA	520 tax ID

Genome sequence information:

	Sequence accession description	Seq. accession number	Assembly level (bp)	Sequence database	Associated NCBI tax ID
[Ref.: #66792]	Bordetella pertussis 18323 18323	GCA_000306945	complete	GenBank	568706 tax ID	*
[Ref.: #66792]	Bordetella pertussis 18323	568706.3	complete	PATRIC	568706 tax ID	*
[Ref.: #66792]	Bordetella pertussis 18323	568706.6	wgs	PATRIC	568706 tax ID	*
[Ref.: #66792]	Bordetella pertussis 18323	2912183561	draft	JGI IMG/M	568706 tax ID	*

[Ref.: #22906]

GC-content

63.8 mol%

Availability in culture collections External links

[Ref.: #2227]

Culture collection no.

DSM 5571, ATCC 9797, CCUG 30873, CCUG 17764, NCTC 10739, LMG 14455, CIP 63.1

[Ref.: #20218]

Associated Passport(s) in StrainInfo

38926, 38922

Literature:

Only first 10 entries are displayed. Click here to see all.

Title	Authors	Journal	DOI	Year	Mesh	Topic	Topic2
[Isolation and purification of a preparation possessing leukocytosis-stimulating properties from pertussis bacteria].	Trofimova NP, Demina AA, Igonina IuA, Dolomanova MS, Syresina GI	Zh Mikrobiol Epidemiol Immunobiol		1977	Animals, Antigens, Bacterial/isolation & purification, Bacterial Proteins/isolation & purification, Bacterial Toxins/isolation & purification, Body Weight, Bordetella pertussis/analysis, Leukocytosis/chemically induced, Mice, Pertussis Vaccine/isolation & purification, Vaccination, Whooping Cough/prevention & control	Enzymology	Phylogeny	*
Bordetella pertussis extract induces increase in the activities of glycolytic enzymes in mouse liver.	Shyamala S, Sengupta SR, Ramakrishnan P	Indian J Biochem Biophys		1992	Animals, Bordetella pertussis, Glucokinase/metabolism, Glucosephosphate Dehydrogenase/metabolism, Glyceraldehyde-3-Phosphate Dehydrogenases/metabolism, Glycolysis/drug effects, L-Lactate Dehydrogenase/metabolism, Liver/drug effects/enzymology, Male, Mice, Pertussis Vaccine/pharmacology, Phosphofructokinase-1/metabolism, Pyruvate Kinase/metabolism, Time Factors	Metabolism	Enzymology	*
Pertussis whole cell vaccine: relation between intracerebral protection in mice and antibody response to pertussis toxin, filamentous hemagglutinin and adenylate cyclase.	Dellepiane NI, Manghi MA, Eriksson PV, di Paola G, Cangelosi A	Zentralbl Bakteriol	10.1016/s0934-8840(11)80872-8	1992	Adenylate Cyclase Toxin, Adenylyl Cyclases/immunology, Animals, Antibodies, Bacterial/biosynthesis, Antigens, Bacterial/immunology, Brain Diseases/immunology/microbiology/prevention & control, Female, Hemagglutinins/immunology, Male, Mice, Pertussis Toxin, Pertussis Vaccine/immunology/standards, Virulence Factors, Bordetella/immunology, Whooping Cough/mortality/prevention & control/veterinary			*
A vir-repressed gene of Bordetella pertussis is required for virulence.	Beattie DT, Shahin R, Mekalanos JJ	Infect Immun	10.1128/iai.60.2.571-577.1992	1992	Amino Acid Sequence, Base Sequence, Bordetella pertussis/genetics/pathogenicity, Cloning, Molecular, Gene Expression, Genes, Bacterial, Molecular Sequence Data, Mutation, Virulence	Enzymology	Genetics	*
[Structural organization of a segment of chromosome, containing the vir gene of Bordetella pertussis].	Karataev GI, Shumakov IuL, Kirillov MIu, Volgina TI, Lapaeva IA	Mol Gen Mikrobiol Virusol		1990	Bordetella pertussis/genetics/pathogenicity, Chromosomes, Bacterial, Cloning, Molecular, DNA, Bacterial/genetics/isolation & purification, Deoxyribonuclease BamHI/genetics, Genes, Bacterial, Nucleic Acid Hybridization, Operon, Plasmids, Restriction Mapping	Enzymology	Phylogeny	*
Pertussis toxin analog with reduced enzymatic and biological activities is a protective immunogen.	Kimura A, Mountzouros KT, Schad PA, Cieplak W, Cowell JL	Infect Immun	10.1128/iai.58.10.3337-3347.1990	1990	Anaphylaxis/etiology, Animals, Bacterial Vaccines/immunology/isolation & purification/metabolism, Bordetella Infections/prevention & control, Bordetella pertussis/immunology, Cells, Cultured, Chi-Square Distribution, Colony Count, Microbial, Enzyme-Linked Immunosorbent Assay, Hemagglutination Tests, Histamine/administration & dosage, Hypersensitivity, Immediate/chemically induced, Immunization, Immunization, Passive, Leukocyte Count, Mice, Mice, Inbred BALB C, Mitogens, Mixed Function Oxygenases/metabolism, Neutralization Tests, Poly(ADP-ribose) Polymerases/metabolism, Toxoids/immunology/isolation & purification/metabolism	Metabolism	Enzymology	*
Characterization of the protective capacity and immunogenicity of the 69-kD outer membrane protein of Bordetella pertussis.	Shahin RD, Brennan MJ, Li ZM, Meade BD, Manclark CR	J Exp Med	10.1084/jem.171.1.63	1990	Animals, Antibodies, Monoclonal, Bacterial Outer Membrane Proteins/immunology/isolation & purification/metabolism, Bordetella pertussis/immunology/pathogenicity/physiology, Immunization, Immunization, Passive, Mice, Mice, Inbred BALB C, Molecular Weight, Whooping Cough/*immunology	Enzymology	Phylogeny	*
Construction and characterization in vivo of Bordetella pertussis aroA mutants.	Roberts M, Maskell D, Novotny P, Dougan G	Infect Immun	10.1128/iai.58.3.732-739.1990	1990	Aerosols, Animals, Antibodies, Bacterial/analysis, Bacterial Vaccines/immunology, Bordetella pertussis/genetics/immunology/physiology, Escherichia coli/genetics, Female, Genotype, Lung/microbiology, Mice, *Mutation, Phenotype, Vaccination, Vaccines, Attenuated/immunology	Genetics	Phenotype	*
Purification of serotype 2 fimbriae of Bordetella pertussis and their identification as a mouse protective antigen.	Zhang JM, Cowell JL, Steven AC, Manclark CR	Dev Biol Stand		1985	Animals, Antigens, Bacterial/immunology/isolation & purification, Bordetella pertussis/classification/immunology/ultrastructure, Brain Diseases/prevention & control, Fimbriae, Bacterial/*immunology/ultrastructure, Hemagglutinins/isolation & purification, Immunization, Mice, Molecular Weight, Pertussis Vaccine/isolation & purification, Respiratory Tract Infections/prevention & control, Serotyping, Whooping Cough/prevention & control	Enzymology	Phylogeny	*
Studies on phase variation in Bordetella pertussis.	Goldman S, Hanski E, Fish F	Dev Biol Stand		1985	Adaptation, Physiological, Adenylate Cyclase Toxin, Bordetella pertussis/genetics/pathogenicity/*physiology, Culture Media, Genetic Variation, Hemagglutinins/isolation & purification, Hemolysin Proteins/isolation & purification, Pertussis Toxin, Phenotype, Species Specificity, Virulence Factors, Bordetella/isolation & purification	Phylogeny	Enzymology	*
Bordetella adenylate cyclase: a genus specific protective antigen and virulence factor.	Novotny P, Chubb AP, Cownley K, Montaraz JA, Beesley JE	Dev Biol Stand		1985	Adenylyl Cyclases/immunology/isolation & purification, Animals, Antigens, Bacterial/isolation & purification, Antigens, Surface/immunology, Bordetella/enzymology/immunology/pathogenicity, Bordetella Infections/prevention & control, Bordetella pertussis/enzymology/immunology/pathogenicity, Disease Models, Animal, Female, Immunity, Maternally-Acquired, Immunization, Passive, Mice, Pregnancy, Rhinitis, Atrophic/prevention & control, Species Specificity	Enzymology	Phylogeny	*
Antigenic heterogeneity in subunit S1 of pertussis toxin.	Perera VY, Wardlaw AC, Freer JH	J Gen Microbiol	10.1099/00221287-132-2-553	1986	Antigens, Bacterial/immunology, Bordetella pertussis/immunology, Enzyme-Linked Immunosorbent Assay, Macromolecular Substances, Pertussis Toxin, Virulence Factors, Bordetella/*immunology			*
Evolutionary relationships in the genus Bordetella.	Arico B, Gross R, Smida J, Rappuoli R	Mol Microbiol	10.1111/j.1365-2958.1987.tb01936.x	1987	Amino Acid Sequence, Base Sequence, Biological Evolution, Bordetella/genetics, Bordetella pertussis/genetics, DNA, Bacterial/genetics, Genes, Genes, Bacterial, Molecular Sequence Data, Pertussis Toxin, Species Specificity, Virulence Factors, Bordetella/genetics	Genetics	Phylogeny	*
Spontaneous phase variation in Bordetella pertussis is a multistep non-random process.	Goldman S, Hanski E, Fish F	EMBO J	10.1002/j.1460-2075.1984.tb01976.x	1984	Adenylate Cyclase Toxin, Adenylyl Cyclases/metabolism, Bacterial Toxins/analysis, Bordetella pertussis/genetics/pathogenicity, Gene Frequency, Genetic Variation, Hemagglutinins/analysis, Hemolysin Proteins/analysis, Pertussis Toxin, Phenotype, Virulence, Virulence Factors, Bordetella	Phenotype	Metabolism	*
Transplacental and transcolostral immunity to pertussis in a mouse model using acellular pertussis vaccine.	Oda M, Izumiya K, Sato Y, Hirayama M	J Infect Dis	10.1093/infdis/148.1.138	1983	Animals, Antibodies, Bacterial/biosynthesis, Body Weight, Bordetella pertussis/immunology, Disease Models, Animal, Female, Immunity, Maternally-Acquired, Lactation, Mice, Pertussis Vaccine/administration & dosage, Pregnancy, Time Factors, Whooping Cough/immunology/mortality/prevention & control			*
Tracheal colonization factor: a Bordetella pertussis secreted virulence determinant.	Finn TM, Stevens LA	Mol Microbiol	10.1111/j.1365-2958.1995.tb02425.x	1995	Amino Acid Sequence, Animals, Bacterial Proteins/biosynthesis/genetics, Base Sequence, Bordetella/genetics, Bordetella pertussis/genetics/pathogenicity, Cloning, Molecular, DNA, Bacterial/genetics, Genes, Bacterial, Lymphocytosis/etiology, Mice, Molecular Sequence Data, RNA, Bacterial/genetics, RNA, Messenger/genetics, Rabbits, Species Specificity, Trachea/microbiology, Virulence/genetics, Virulence Factors, Bordetella	Enzymology	Genetics	*
Identification of a Bordetella pertussis bvg-regulated porin-like protein.	Finn TM, Li Z, Kocsis E	J Bacteriol	10.1128/jb.177.3.805-809.1995	1995	Amino Acid Sequence, Animals, Base Sequence, Bordetella pertussis/genetics/pathogenicity, Cloning, Molecular, Electrophoresis, Polyacrylamide Gel, Genes, Bacterial, Mice, Molecular Sequence Data, Porins/analysis/chemistry/*genetics	Enzymology	Genetics	*
Vag8, a Bordetella pertussis bvg-regulated protein.	Finn TM, Amsbaugh DF	Infect Immun	10.1128/IAI.66.8.3985-3989.1998	1998	Alkaline Phosphatase/metabolism, Animals, Bacterial Proteins/genetics/immunology/metabolism, Base Sequence, Bordetella/metabolism, Bordetella pertussis/genetics/immunology/metabolism/physiology, Chloramphenicol O-Acetyltransferase/metabolism, Chromosomes, Bacterial, Cloning, Molecular, DNA, Bacterial, Female, Mice, Mice, Inbred BALB C, Molecular Sequence Data, Mutagenesis, Plasmids, Recombinant Fusion Proteins/genetics/immunology, Sequence Analysis, Sequence Analysis, DNA, Trans-Activators/metabolism	Metabolism	Transcriptome	*
Intranasal murine model of Bordetella pertussis infection: II. Sequence variation and protection induced by a tricomponent acellular vaccine.	Boursaux-Eude C, Thiberge S, Carletti G, Guiso N	Vaccine	10.1016/s0264-410x(99)00038-9	1999	Adhesins, Bacterial/genetics, Amino Acid Sequence, Animals, Bacterial Outer Membrane Proteins/genetics, Bordetella pertussis/classification, Diphtheria-Tetanus-Pertussis Vaccine/immunology, Female, Genes, Bacterial, Hemagglutinins/genetics, Lung/microbiology, Mice, Mice, Inbred BALB C, Molecular Sequence Data, Pertussis Toxin, Vaccines, Synthetic/immunology, Virulence Factors, Bordetella/genetics, Whooping Cough/prevention & control	Genetics	Phylogeny	*
The Pertussis Serological Potency Test. Collaborative study to evaluatereplacement of the Mouse Protection Test.	van der Ark A, van Straaten-van de Kappelle I, Olander RM, Enssle K, Jadhav S, van de Donk H, Hendriksen C	Biologicals	10.1006/biol.2000.0247	2000	Animal Testing Alternatives, Animals, Antibodies, Bacterial/biosynthesis, Biological Assay, Bordetella pertussis/immunology, Dose-Response Relationship, Immunologic, Enzyme-Linked Immunosorbent Assay, Evaluation Studies as Topic, Female, Male, Mice, Pertussis Vaccine/immunology/standards, Pilot Projects, Quality Control, Random Allocation, Reproducibility of Results, Safety, Whooping Cough/prevention & control, World Health Organization			*
Mass spectrometric analysis of recombinant adenylate cyclase toxin from Bordetella pertussis strain 18323/pHSP9.	Havlicek V, Higgins L, Chen W, Halada P, Sebo P, Sakamoto H, Hackett M	J Mass Spectrom	10.1002/jms.139	2001	Adenylate Cyclase Toxin, Adenylyl Cyclases/analysis, Amino Acid Sequence, Bacterial Proteins/chemistry, Bordetella pertussis/enzymology, Chromatography, High Pressure Liquid/methods, Molecular Sequence Data, Recombinant Proteins/chemistry, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods, Virulence Factors, Bordetella/*chemistry	Genetics	Enzymology	*
Mitochondrial alterations precede Bordetella pertussis-induced apoptosis.	Bachelet M, Richard MJ, Francois D, Polla BS	FEMS Immunol Med Microbiol	10.1111/j.1574-695X.2002.tb00544.x	2002	Adenosine Triphosphate/metabolism, Adenylate Cyclase Toxin, Apoptosis, Bordetella pertussis/physiology, Cells, Cultured, Cyclic AMP/metabolism, Humans, Intracellular Fluid/metabolism, Intracellular Membranes/drug effects/physiology, Membrane Potentials/drug effects/physiology, Microscopy, Electron, Mitochondria/drug effects/microbiology/*physiology/ultrastructure, Monocytes/cytology/metabolism/microbiology/physiology, Virulence Factors, Bordetella/pharmacology	Pathogenicity	Metabolism	*
Sequence variation and conservation in virulence-related genes of Bordetella pertussis isolates from the UK.	Packard ER, Parton R, Coote JG, Fry NK	J Med Microbiol	10.1099/jmm.0.05515-0	2004	Amino Acid Sequence, Bacterial Proteins/chemistry/genetics/metabolism, Bacterial Typing Techniques, Base Sequence, Bordetella pertussis/classification/genetics/pathogenicity, Conserved Sequence, Genetic Variation, Humans, Molecular Sequence Data, Pertussis Vaccine, Sequence Analysis, DNA, United Kingdom/epidemiology, Virulence/genetics, Whooping Cough/epidemiology/microbiology	Pathogenicity	Genetics	*
Evaluation of two serological methods for potency testing of whole cell pertussis vaccines.	von Hunolstein C, Gomez Miguel MJ, Pezzella C, Scopetti F, Behr-Gross ME, Halder M, Hoffmann S, Levels L, van der Gun J, Hendriksen C	Pharmeuropa Bio		2008	Animals, CHO Cells, Cricetinae, Cricetulus, Enzyme-Linked Immunosorbent Assay/methods/standards, Europe, Female, Guinea Pigs, Immunity, Cellular/immunology, Male, Mice, Pertussis Vaccine/immunology/standards, Serologic Tests/*methods			*
A natural pertactin deficient strain of Bordetella pertussis shows improved entry in human monocyte-derived dendritic cells.	Stefanelli P, Fazio C, Fedele G, Spensieri F, Ausiello CM, Mastrantonio P	New Microbiol		2009	Animals, Antigens, CD/biosynthesis, B7-1 Antigen/biosynthesis, Bacterial Outer Membrane Proteins/metabolism, Bordetella pertussis/isolation & purification/metabolism/pathogenicity, Cell Culture Techniques, Dendritic Cells/immunology/metabolism/microbiology, HLA-DR Antigens/biosynthesis, Humans, Immunoglobulins/biosynthesis, Infant, Interleukins/biosynthesis, Membrane Glycoproteins/biosynthesis, Mice, Monocytes/cytology/immunology, Virulence, Virulence Factors, Bordetella/metabolism, Whooping Cough/immunology/microbiology	Metabolism	Pathogenicity	*
Parapusillimonas granuli gen. nov., sp. nov., isolated from granules from a wastewater-treatment bioreactor.	Kim YJ, Kim MK, Im WT, Srinivasan S, Yang DC	Int J Syst Evol Microbiol	10.1099/ijs.0.009720-0	2009	Alcaligenaceae/classification/*genetics/isolation & purification, Base Sequence, Carboxylic Acids/metabolism, Cell Size, DNA, Bacterial/genetics, Enzymes/metabolism, Glucose/metabolism, Molecular Sequence Data, Phylogeny, Quinones/metabolism, RNA, Bacterial/genetics, RNA, Ribosomal, 16S/genetics	Phylogeny	Metabolism	*
Bactericidal activity of topical antiseptics and their gargles against Bordetella pertussis.	Suzuki T, Kataoka H, Ida T, Kamachi K, Mikuniya T	J Infect Chemother	10.1007/s10156-011-0312-4	2011	Administration, Topical, Anti-Infective Agents, Local/pharmacology, Benzalkonium Compounds/pharmacology, Benzethonium/pharmacology, Bordetella pertussis/drug effects/isolation & purification, Chlorhexidine/analogs & derivatives/pharmacology, Colony Count, Microbial, Humans, Mouthwashes/pharmacology, Povidone-Iodine/pharmacology, Whooping Cough/microbiology	Pathogenicity	Enzymology	*
The Bordetella pertussis type III secretion system tip complex protein Bsp22 is not a protective antigen and fails to elicit serum antibody responses during infection of humans and mice.	Villarino Romero R, Bibova I, Cerny O, Vecerek B, Wald T, Benada O, Zavadilova J, Osicka R, Sebo P	Infect Immun	10.1128/IAI.00353-13	2013	Animals, Antibodies, Bacterial/blood/immunology, Antibody Formation/immunology, Antigens, Bacterial/immunology, Bacterial Proteins/immunology, Bordetella Infections/immunology, Bordetella pertussis/immunology, Enzyme-Linked Immunosorbent Assay, Humans, Mice, Mice, Inbred BALB C, Whooping Cough/*immunology	Pathogenicity		*
The RNA chaperone Hfq is required for virulence of Bordetella pertussis.	Bibova I, Skopova K, Masin J, Cerny O, Hot D, Sebo P, Vecerek B	Infect Immun	10.1128/IAI.00345-13	2013	Animals, Bacterial Load, Bordetella pertussis/genetics/pathogenicity, Disease Models, Animal, Gene Deletion, Gene Expression Regulation, Bacterial, Host Factor 1 Protein/genetics/metabolism, Lethal Dose 50, Lung/microbiology, Mice, Pertussis Toxin/metabolism, Survival Analysis, Virulence, Virulence Factors/genetics/*metabolism, Whooping Cough/microbiology/pathology	Metabolism	Pathogenicity	*
[Preclinical studies of an adsorbed diphtheria-tetanus-pertussis vaccine (ADTP-vaccine) with acellular pertussis component].	Zaitsev EM, Britsina MV, Bazhanova IG, Mertsalova NU, Ozeretskovskaia MN, Ermolova EV, Plekhanova NG, Mikhailova NA, Kolyshkin VA, Zverev VV	Zh Mikrobiol Epidemiol Immunobiol		2013	Adjuvants, Immunologic/adverse effects/pharmacology, Aluminum Hydroxide/adverse effects/pharmacology, Animals, Antigens, Bacterial/adverse effects/immunology/pharmacology, Bordetella pertussis, Diphtheria Toxin/immunology/toxicity, Diphtheria-Tetanus-acellular Pertussis Vaccines/adverse effects/immunology/pharmacology, Drug Evaluation, Preclinical, Female, Guinea Pigs, Humans, Male, Meningoencephalitis/immunology/prevention & control, Mice, Tetanus Toxin/immunology/toxicity	Pathogenicity		*
[Immunobiological properties of Bordetella pertussis lipopolysaccharide in the acellular pertussis vaccine].	Zaitsev EM, Poddubikov AV, Britsina MV, Mertsalova NU, Ozeretskovskaia MN, Bazhanova IG, Plekhanova NG	Zh Mikrobiol Epidemiol Immunobiol		2014	Animals, Antigens, Bacterial/chemistry/immunology/pharmacology, Bordetella pertussis/chemistry/immunology, Humans, Lipopolysaccharides/chemistry/immunology/pharmacology, Mice, Pertussis Vaccine/chemistry/immunology/pharmacology, Vaccines, Acellular/chemistry/immunology/pharmacology, Virulence Factors, Bordetella/chemistry/immunology/pharmacology, Whooping Cough/immunology/prevention & control	Pathogenicity		*
Genetic analysis of clinical and vaccine strains of Bordetella pertussis by Pulsed-Field Gel Electrophoresis (PFGE), Multi Locus Sequence Typing (MLST) and serotyping.	Bahmanjeh A, Noofeli M, Khaki P, Hassanzadeh SM	Comp Immunol Microbiol Infect Dis	10.1016/j.cimid.2019.03.010	2019	Bacterial Typing Techniques, Bordetella pertussis/classification/genetics, DNA Fingerprinting, Electrophoresis, Gel, Pulsed-Field, Genetic Profile, Genetic Variation, Genotype, Multilocus Sequence Typing, Pertussis Vaccine, Serotyping, Whooping Cough/microbiology	Enzymology	Genetics	*
Comparative Assessment of the Whole-cell Pertussis Vaccine Potency Using Serological and Intracerebral Mouse Protection Methods.	Mohammadbagher D, Noofeli M, Karimi G	Arch Razi Inst	10.22092/ari.2018.108852.1096	2019	Animals, Bordetella pertussis/immunology, Female, Immunization, Male, Mice, Pertussis Vaccine/pharmacology, Serologic Tests, Vaccine Potency			*

References

#2227

Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 5571

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#20218

Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )

#22905

P. VANDAMME, M. HEYNDRICKX, M. VANCANNEYT, B. HOSTE, P. DE VOS, E. FALSEN, K. KERSTERS, K.-H. HINZ: Bordetella trematum sp. nov., Isolated from Wounds and Ear Infections in Humans, and Reassessment of Alcaligenes denitrificans Rüger and Tan 1983. IJSEM 46: 849 - 858 1996 ( DOI 10.1099/00207713-46-4-849 , PubMed 8863408 )

#22906

Yeon-Ju Kim, Myung Kyum Kim, Wan-Taek Im, Sathiyaraj Srinivasan, Deok-Chun Yang: Parapusillimonas granuli gen. nov., sp. nov., isolated from granules from a wastewater-treatment bioreactor. IJSEM 60: 1401 - 1406 2010 ( DOI 10.1099/ijs.0.009720-0 , PubMed 19671719 )

#39796 ; Curators of the CIP;
#50311 Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 30873

#66792

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#68377

Automatically annotated from API NH .

* These data were automatically processed and therefore are not curated

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