Bordetella pertussis Sato is a mesophilic, Gram-negative, rod-shaped prokaryote of the family Alcaligenaceae.
Gram-negative rod-shaped mesophilic 16S sequence| @ref 20215 |
Last LPSN update
2025-12-16 10:03:14 |
| Domain Pseudomonadati |
| Phylum Pseudomonadota |
| Class Betaproteobacteria |
| Order Burkholderiales |
| Family Alcaligenaceae |
| Genus Bordetella |
| Species Bordetella pertussis |
| Full scientific name Bordetella pertussis (Bergey et al. 1923) Moreno-López 1952 (Approved Lists 1980) |
| Synonyms (1) |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68371 | 27613 ChEBI | amygdalin | - | builds acid from | from API 50CH acid |
| 68371 | 18305 ChEBI | arbutin | - | builds acid from | from API 50CH acid |
| 68371 | 17057 ChEBI | cellobiose | - | builds acid from | from API 50CH acid |
| 68371 | 17108 ChEBI | D-arabinose | - | builds acid from | from API 50CH acid |
| 68371 | 18333 ChEBI | D-arabitol | - | builds acid from | from API 50CH acid |
| 68371 | 15824 ChEBI | D-fructose | - | builds acid from | from API 50CH acid |
| 68371 | 28847 ChEBI | D-fucose | - | builds acid from | from API 50CH acid |
| 68371 | 12936 ChEBI | D-galactose | - | builds acid from | from API 50CH acid |
| 68371 | 17634 ChEBI | D-glucose | - | builds acid from | from API 50CH acid |
| 68371 | 62318 ChEBI | D-lyxose | - | builds acid from | from API 50CH acid |
| 68371 | 16899 ChEBI | D-mannitol | - | builds acid from | from API 50CH acid |
| 68371 | 16024 ChEBI | D-mannose | - | builds acid from | from API 50CH acid |
| 68371 | 16988 ChEBI | D-ribose | - | builds acid from | from API 50CH acid |
| 68371 | 17924 ChEBI | D-sorbitol | - | builds acid from | from API 50CH acid |
| 68371 | 16443 ChEBI | D-tagatose | - | builds acid from | from API 50CH acid |
| 68371 | 65327 ChEBI | D-xylose | - | builds acid from | from API 50CH acid |
| 68371 | 17113 ChEBI | erythritol | - | builds acid from | from API 50CH acid |
| 41116 | 4853 ChEBI | esculin | - | hydrolysis | |
| 68371 | 4853 ChEBI | esculin | - | builds acid from | from API 50CH acid |
| 68371 | 16813 ChEBI | galactitol | - | builds acid from | from API 50CH acid |
| 68371 | 28066 ChEBI | gentiobiose | - | builds acid from | from API 50CH acid |
| 68371 | 24265 ChEBI | gluconate | - | builds acid from | from API 50CH acid |
| 41116 | 17234 ChEBI | glucose | - | degradation | |
| 68371 | 17754 ChEBI | glycerol | - | builds acid from | from API 50CH acid |
| 68371 | 28087 ChEBI | glycogen | - | builds acid from | from API 50CH acid |
| 41116 | 606565 ChEBI | hippurate | + | hydrolysis | |
| 68371 | 15443 ChEBI | inulin | - | builds acid from | from API 50CH acid |
| 68371 | 30849 ChEBI | L-arabinose | - | builds acid from | from API 50CH acid |
| 68371 | 18403 ChEBI | L-arabitol | - | builds acid from | from API 50CH acid |
| 68371 | 18287 ChEBI | L-fucose | - | builds acid from | from API 50CH acid |
| 68371 | 62345 ChEBI | L-rhamnose | - | builds acid from | from API 50CH acid |
| 68371 | 17266 ChEBI | L-sorbose | - | builds acid from | from API 50CH acid |
| 68371 | 65328 ChEBI | L-xylose | - | builds acid from | from API 50CH acid |
| 68371 | 17716 ChEBI | lactose | - | builds acid from | from API 50CH acid |
| 68371 | 17306 ChEBI | maltose | - | builds acid from | from API 50CH acid |
| 68371 | 6731 ChEBI | melezitose | - | builds acid from | from API 50CH acid |
| 68371 | 28053 ChEBI | melibiose | - | builds acid from | from API 50CH acid |
| 68371 | 320061 ChEBI | methyl alpha-D-glucopyranoside | - | builds acid from | from API 50CH acid |
| 68371 | 43943 ChEBI | methyl alpha-D-mannoside | - | builds acid from | from API 50CH acid |
| 68371 | 74863 ChEBI | methyl beta-D-xylopyranoside | - | builds acid from | from API 50CH acid |
| 68371 | 17268 ChEBI | myo-inositol | - | builds acid from | from API 50CH acid |
| 68371 | 59640 ChEBI | N-acetylglucosamine | - | builds acid from | from API 50CH acid |
| 41116 | 17632 ChEBI | nitrate | - | builds gas from | |
| 41116 | 17632 ChEBI | nitrate | - | reduction | |
| 41116 | 16301 ChEBI | nitrite | - | builds gas from | |
| 41116 | 16301 ChEBI | nitrite | - | reduction | |
| 68371 | Potassium 2-ketogluconate | - | builds acid from | from API 50CH acid | |
| 68371 | Potassium 5-ketogluconate | - | builds acid from | from API 50CH acid | |
| 68371 | 16634 ChEBI | raffinose | - | builds acid from | from API 50CH acid |
| 68371 | 15963 ChEBI | ribitol | - | builds acid from | from API 50CH acid |
| 68371 | 17814 ChEBI | salicin | - | builds acid from | from API 50CH acid |
| 68371 | 28017 ChEBI | starch | - | builds acid from | from API 50CH acid |
| 68371 | 17992 ChEBI | sucrose | - | builds acid from | from API 50CH acid |
| 68371 | 27082 ChEBI | trehalose | - | builds acid from | from API 50CH acid |
| 68371 | 32528 ChEBI | turanose | - | builds acid from | from API 50CH acid |
| 68371 | 17151 ChEBI | xylitol | - | builds acid from | from API 50CH acid |
| @ref | Metabolite | Is antibiotic | Is sensitive | Is resistant | |
|---|---|---|---|---|---|
| 41116 | 0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate) |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 41116 | alcohol dehydrogenase | - | 1.1.1.1 | |
| 68382 | alkaline phosphatase | - | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | + | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 41116 | beta-galactosidase | - | 3.2.1.23 | |
| 68382 | beta-glucosidase | - | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 41116 | catalase | + | 1.11.1.6 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 68382 | esterase (C 4) | + | from API zym | |
| 68382 | esterase lipase (C 8) | + | from API zym | |
| 41116 | gamma-glutamyltransferase | + | 2.3.2.2 | |
| 41116 | gelatinase | - | ||
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 68382 | lipase (C 14) | - | from API zym | |
| 41116 | lysine decarboxylase | - | 4.1.1.18 | |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 41116 | ornithine decarboxylase | - | 4.1.1.17 | |
| 41116 | oxidase | + | ||
| 41116 | phenylalanine ammonia-lyase | - | 4.3.1.24 | |
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 41116 | tryptophan deaminase | - | ||
| 41116 | urease | - | 3.5.1.5 | |
| 68382 | valine arylamidase | - | from API zym |
| @ref | ControlQ | GLY | ERY | DARA | LARA | RIB | DXYL | LXYL | ADO | MDX | GAL | GLU | FRU | MNE | SBE | RHA | DUL | INO | MAN | SOR | MDM | MDG | NAG | AMY | ARB | ESC | SAL | CEL | MAL | LAC | MEL | SAC | TRE | INU | MLZ | RAF | AMD | GLYG | XLT | GEN | TUR | LYX | TAG | DFUC | LFUC | DARL | LARL | GNT | 2KG | 5KG | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 41116 | not determinedn.d. | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 124043 | Bordetella pertussis strain Tohama 16S ribosomal RNA gene, partial sequence. | AF142326 | 1477 |  | 520 | |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Less reactogenic whole-cell pertussis vaccine confers protection from Bordetella pertussis infection. | Skopova K, Holubova J, Bockova B, Slivenecka E, Santos de Barros JM, Stanek O, Sebo P. | mSphere | 10.1128/msphere.00639-24 | 2025 | | |
| Limited response of primary nasal epithelial cells to Bordetella pertussis infection. | Zmuda M, Malcova I, Pravdova B, Cerny O, Vondrova D, Kamanova J. | Microbiol Spectr | 10.1128/spectrum.01267-25 | 2025 | | |
| Proteome | Intranasal application of a bifunctional pertactin-RTX fusion antigen elicits protection of mouse airway mucosa against Bordetella pertussis colonization. | Espinosa-Vinals C, Holubova J, Stanek O, Osicka R, Masin J, Arellano Herencia FE, Sebo P. | mSphere | 10.1128/msphere.00959-24 | 2025 | |
| cAMP signaling of Bordetella adenylate cyclase toxin blocks M-CSF triggered upregulation of iron acquisition receptors on differentiating CD14+ monocytes. | Ahmad JN, Sebo P. | mSphere | 10.1128/msphere.00407-24 | 2024 | | |
| The Fim and FhaB adhesins play a crucial role in nasal cavity infection and Bordetella pertussis transmission in a novel mouse catarrhal infection model. | Holubova J, Stanek O, Juhasz A, Hamidou Soumana I, Makovicky P, Sebo P. | PLoS Pathog | 10.1371/journal.ppat.1010402 | 2022 | | |
| Latest Update on Outer Membrane Vesicles and Their Role in Horizontal Gene Transfer: A Mini-Review. | Marinacci B, Krzyzek P, Pellegrini B, Turacchio G, Grande R. | Membranes (Basel) | 10.3390/membranes13110860 | 2023 | | |
| Filamentous Hemagglutinin of Bordetella pertussis Does Not Interact with the beta2 Integrin CD11b/CD18. | Golshani M, Rahman WU, Osickova A, Holubova J, Lora J, Balashova N, Sebo P, Osicka R. | Int J Mol Sci | 10.3390/ijms232012598 | 2022 | | |
| Pathogenicity | Bordetella Adenylate Cyclase Toxin Inhibits Monocyte-to-Macrophage Transition and Dedifferentiates Human Alveolar Macrophages into Monocyte-like Cells. | Ahmad JN, Holubova J, Benada O, Kofronova O, Stehlik L, Vasakova M, Sebo P. | mBio | 10.1128/mbio.01743-19 | 2019 | |
| Metabolism | Selective Enhancement of the Cell-Permeabilizing Activity of Adenylate Cyclase Toxin Does Not Increase Virulence of Bordetella pertussis. | Holubova J, Juhasz A, Masin J, Stanek O, Jurnecka D, Osickova A, Sebo P, Osicka R. | Int J Mol Sci | 10.3390/ijms222111655 | 2021 | |
| Metabolism | Bordetella Adenylate Cyclase Toxin Elicits Airway Mucin Secretion through Activation of the cAMP Response Element Binding Protein. | Malandra A, Rahman WU, Klimova N, Streparola G, Holubova J, Osickova A, Bariselli S, Sebo P, Osicka R. | Int J Mol Sci | 10.3390/ijms22169064 | 2021 | |
| Pathogenicity | A Mutation Upstream of the rplN-rpsD Ribosomal Operon Downregulates Bordetella pertussis Virulence Factor Production without Compromising Bacterial Survival within Human Macrophages. | Novak J, Jurnecka D, Linhartova I, Holubova J, Stanek O, Stipl D, Dienstbier A, Vecerek B, Azevedo N, Provaznik J, Benes V, Sebo P. | mSystems | 10.1128/msystems.00612-20 | 2020 | |
| Pertussis toxin suppresses dendritic cell-mediated delivery of B. pertussis into lung-draining lymph nodes. | Klimova N, Holubova J, Streparola G, Tomala J, Brazdilova L, Stanek O, Bumba L, Sebo P. | PLoS Pathog | 10.1371/journal.ppat.1010577 | 2022 | | |
| Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins. | Lepesheva A, Osickova A, Holubova J, Jurnecka D, Knoblochova S, Espinosa-Vinals C, Bumba L, Skopova K, Fiser R, Osicka R, Sebo P, Masin J. | Sci Rep | 10.1038/s41598-021-99112-3 | 2021 | | |
| Metabolism | Bordetella pertussis Adenylate Cyclase Toxin Disrupts Functional Integrity of Bronchial Epithelial Layers. | Hasan S, Kulkarni NN, Asbjarnarson A, Linhartova I, Osicka R, Sebo P, Gudmundsson GH. | Infect Immun | 10.1128/iai.00445-17 | 2018 | |
| The rtxA toxin gene of Kingella kingae: a pertinent target for molecular diagnosis of osteoarticular infections. | Lehours P, Freydiere AM, Richer O, Burucoa C, Boisset S, Lanotte P, Prere MF, Ferroni A, Lafuente C, Vandenesch F, Megraud F, Menard A. | J Clin Microbiol | 10.1128/jcm.01657-10 | 2011 | | |
| Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes. | Arico B, Rappuoli R. | J Bacteriol | 10.1128/jb.169.6.2847-2853.1987 | 1987 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive139078.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
License