Bordetella pertussis (CIP 81.32, CCUG 17138, Sato (Tohama Phase 1))
BacDive ID
139078
Type strain
Strain Designation
Sato (Tohama Phase 1)
NCBI tax ID(s)
520
History
CIP <- 1981, Lab. Ident. Inst. Pasteur, Paris, France <- E. Relyveld <- Bur. Biol., Bethesda, USA: BB4, strain Sato (Tohama Phase 1)
Links
Bordetella pertussis Sato is a Gram-negative, rod-shaped bacterium of the family Alcaligenaceae.
Gram-negative rod-shaped 16S sequence BacteriaName and taxonomic classification
| @ref 20215 |
|
Last LPSN update
2026-05-29 08:39:24 |
| Domain Bacteria |
| Phylum Pseudomonadota |
| Class Betaproteobacteria |
| Order Burkholderiales |
| Family Alcaligenaceae |
| Genus Bordetella |
| Species Bordetella pertussis |
| Full scientific name Bordetella pertussis (Bergey et al. 1923) Moreno-López 1952 (Approved Lists 1980) |
| Synonyms (1) |
Physiology and metabolism
Metabolite utilization
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68371 | 27613 ChEBI | amygdalin | - | builds acid from | from API 50CH acid |
| 68371 | 18305 ChEBI | arbutin | - | builds acid from | from API 50CH acid |
| 68371 | 17057 ChEBI | cellobiose | - | builds acid from | from API 50CH acid |
| 68371 | 17108 ChEBI | D-arabinose | - | builds acid from | from API 50CH acid |
| 68371 | 18333 ChEBI | D-arabitol | - | builds acid from | from API 50CH acid |
| 68371 | 15824 ChEBI | D-fructose | - | builds acid from | from API 50CH acid |
| 68371 | 28847 ChEBI | D-fucose | - | builds acid from | from API 50CH acid |
| 68371 | 12936 ChEBI | D-galactose | - | builds acid from | from API 50CH acid |
| 68371 | 17634 ChEBI | D-glucose | - | builds acid from | from API 50CH acid |
| 68371 | 62318 ChEBI | D-lyxose | - | builds acid from | from API 50CH acid |
| 68371 | 16899 ChEBI | D-mannitol | - | builds acid from | from API 50CH acid |
| 68371 | 16024 ChEBI | D-mannose | - | builds acid from | from API 50CH acid |
| 68371 | 16988 ChEBI | D-ribose | - | builds acid from | from API 50CH acid |
| 68371 | 17924 ChEBI | D-sorbitol | - | builds acid from | from API 50CH acid |
| 68371 | 16443 ChEBI | D-tagatose | - | builds acid from | from API 50CH acid |
| 68371 | 65327 ChEBI | D-xylose | - | builds acid from | from API 50CH acid |
| 68371 | 17113 ChEBI | erythritol | - | builds acid from | from API 50CH acid |
| 41116 | 4853 ChEBI | esculin | - | hydrolysis | |
| 68371 | 4853 ChEBI | esculin | - | builds acid from | from API 50CH acid |
| 68371 | 16813 ChEBI | galactitol | - | builds acid from | from API 50CH acid |
| 68371 | 28066 ChEBI | gentiobiose | - | builds acid from | from API 50CH acid |
| 68371 | 24265 ChEBI | gluconate | - | builds acid from | from API 50CH acid |
| 41116 | 17234 ChEBI | glucose | - | degradation | |
| 68371 | 17754 ChEBI | glycerol | - | builds acid from | from API 50CH acid |
| 68371 | 28087 ChEBI | glycogen | - | builds acid from | from API 50CH acid |
| 41116 | 606565 ChEBI | hippurate | + | hydrolysis | |
| 68371 | 15443 ChEBI | inulin | - | builds acid from | from API 50CH acid |
| 68371 | 30849 ChEBI | L-arabinose | - | builds acid from | from API 50CH acid |
| 68371 | 18403 ChEBI | L-arabitol | - | builds acid from | from API 50CH acid |
| 68371 | 18287 ChEBI | L-fucose | - | builds acid from | from API 50CH acid |
| 68371 | 62345 ChEBI | L-rhamnose | - | builds acid from | from API 50CH acid |
| 68371 | 17266 ChEBI | L-sorbose | - | builds acid from | from API 50CH acid |
| 68371 | 65328 ChEBI | L-xylose | - | builds acid from | from API 50CH acid |
| 68371 | 17716 ChEBI | lactose | - | builds acid from | from API 50CH acid |
| 68371 | 17306 ChEBI | maltose | - | builds acid from | from API 50CH acid |
| 68371 | 6731 ChEBI | melezitose | - | builds acid from | from API 50CH acid |
| 68371 | 28053 ChEBI | melibiose | - | builds acid from | from API 50CH acid |
| 68371 | 320061 ChEBI | methyl alpha-D-glucopyranoside | - | builds acid from | from API 50CH acid |
| 68371 | 43943 ChEBI | methyl alpha-D-mannoside | - | builds acid from | from API 50CH acid |
| 68371 | 74863 ChEBI | methyl beta-D-xylopyranoside | - | builds acid from | from API 50CH acid |
| 68371 | 17268 ChEBI | myo-inositol | - | builds acid from | from API 50CH acid |
| 68371 | 59640 ChEBI | N-acetylglucosamine | - | builds acid from | from API 50CH acid |
| 41116 | 17632 ChEBI | nitrate | - | builds gas from | |
| 41116 | 17632 ChEBI | nitrate | - | reduction | |
| 41116 | 16301 ChEBI | nitrite | - | builds gas from | |
| 41116 | 16301 ChEBI | nitrite | - | reduction | |
| 68371 | 0 ChEBI | Potassium 2-ketogluconate | - | builds acid from | from API 50CH acid |
| 68371 | 0 ChEBI | Potassium 5-ketogluconate | - | builds acid from | from API 50CH acid |
| 68371 | 16634 ChEBI | raffinose | - | builds acid from | from API 50CH acid |
| 68371 | 15963 ChEBI | ribitol | - | builds acid from | from API 50CH acid |
| 68371 | 17814 ChEBI | salicin | - | builds acid from | from API 50CH acid |
| 68371 | 28017 ChEBI | starch | - | builds acid from | from API 50CH acid |
| 68371 | 17992 ChEBI | sucrose | - | builds acid from | from API 50CH acid |
| 68371 | 27082 ChEBI | trehalose | - | builds acid from | from API 50CH acid |
| 68371 | 32528 ChEBI | turanose | - | builds acid from | from API 50CH acid |
| 68371 | 17151 ChEBI | xylitol | - | builds acid from | from API 50CH acid |
Antibiotic resistance
| @ref | Metabolite | Is sensitive | Is resistant | |
|---|---|---|---|---|
| 41116 | 0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate) |
Metabolite tests
Enzymes
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 41116 | alcohol dehydrogenase | - | 1.1.1.1 | |
| 68382 | alkaline phosphatase | - | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | + | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 41116 | beta-galactosidase | - | 3.2.1.23 | |
| 68382 | beta-glucosidase | - | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 41116 | catalase | + | 1.11.1.6 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 68382 | esterase (C 4) | + | from API zym | |
| 68382 | esterase lipase (C 8) | + | from API zym | |
| 41116 | gamma-glutamyltransferase | + | 2.3.2.2 | |
| 41116 | gelatinase | - | ||
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 68382 | lipase (C 14) | - | from API zym | |
| 41116 | lysine decarboxylase | - | 4.1.1.18 | |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 41116 | ornithine decarboxylase | - | 4.1.1.17 | |
| 41116 | oxidase | + | ||
| 41116 | phenylalanine ammonia-lyase | - | 4.3.1.24 | |
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 41116 | tryptophan deaminase | - | ||
| 41116 | urease | - | 3.5.1.5 | |
| 68382 | valine arylamidase | - | from API zym |
API zym
API 50CHac
| @ref | ControlQ | GLY | ERY | DARA | LARA | RIB | DXYL | LXYL | ADO | MDX | GAL | GLU | FRU | MNE | SBE | RHA | DUL | INO | MAN | SOR | MDM | MDG | NAG | AMY | ARB | ESC | SAL | CEL | MAL | LAC | MEL | SAC | TRE | INU | MLZ | RAF | AMD | GLYG | XLT | GEN | TUR | LYX | TAG | DFUC | LFUC | DARL | LARL | GNT | 2KG | 5KG | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 41116 | not determinedn.d. | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
API biotype100
Sequence information
16S sequences
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 124043 | Bordetella pertussis strain Tohama 16S ribosomal RNA gene, partial sequence. | AF142326 | 1477 |  | 520 | |
Literature
Literature 
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Less reactogenic whole-cell pertussis vaccine confers protection from Bordetella pertussis infection. | Skopova K, Holubova J, Bockova B, Slivenecka E, Santos de Barros JM, Stanek O, Sebo P. | mSphere | 10.1128/msphere.00639-24 | 2025 | | |
| Limited response of primary nasal epithelial cells to Bordetella pertussis infection. | Zmuda M, Malcova I, Pravdova B, Cerny O, Vondrova D, Kamanova J. | Microbiol Spectr | 10.1128/spectrum.01267-25 | 2025 | | |
| Proteome | Intranasal application of a bifunctional pertactin-RTX fusion antigen elicits protection of mouse airway mucosa against Bordetella pertussis colonization. | Espinosa-Vinals C, Holubova J, Stanek O, Osicka R, Masin J, Arellano Herencia FE, Sebo P. | mSphere | 10.1128/msphere.00959-24 | 2025 | |
| cAMP signaling of Bordetella adenylate cyclase toxin blocks M-CSF triggered upregulation of iron acquisition receptors on differentiating CD14+ monocytes. | Ahmad JN, Sebo P. | mSphere | 10.1128/msphere.00407-24 | 2024 | | |
| The Fim and FhaB adhesins play a crucial role in nasal cavity infection and Bordetella pertussis transmission in a novel mouse catarrhal infection model. | Holubova J, Stanek O, Juhasz A, Hamidou Soumana I, Makovicky P, Sebo P. | PLoS Pathog | 10.1371/journal.ppat.1010402 | 2022 | | |
| Latest Update on Outer Membrane Vesicles and Their Role in Horizontal Gene Transfer: A Mini-Review. | Marinacci B, Krzyzek P, Pellegrini B, Turacchio G, Grande R. | Membranes (Basel) | 10.3390/membranes13110860 | 2023 | | |
| Filamentous Hemagglutinin of Bordetella pertussis Does Not Interact with the beta2 Integrin CD11b/CD18. | Golshani M, Rahman WU, Osickova A, Holubova J, Lora J, Balashova N, Sebo P, Osicka R. | Int J Mol Sci | 10.3390/ijms232012598 | 2022 | | |
| Pathogenicity | Bordetella Adenylate Cyclase Toxin Inhibits Monocyte-to-Macrophage Transition and Dedifferentiates Human Alveolar Macrophages into Monocyte-like Cells. | Ahmad JN, Holubova J, Benada O, Kofronova O, Stehlik L, Vasakova M, Sebo P. | mBio | 10.1128/mbio.01743-19 | 2019 | |
| Metabolism | Selective Enhancement of the Cell-Permeabilizing Activity of Adenylate Cyclase Toxin Does Not Increase Virulence of Bordetella pertussis. | Holubova J, Juhasz A, Masin J, Stanek O, Jurnecka D, Osickova A, Sebo P, Osicka R. | Int J Mol Sci | 10.3390/ijms222111655 | 2021 | |
| Metabolism | Bordetella Adenylate Cyclase Toxin Elicits Airway Mucin Secretion through Activation of the cAMP Response Element Binding Protein. | Malandra A, Rahman WU, Klimova N, Streparola G, Holubova J, Osickova A, Bariselli S, Sebo P, Osicka R. | Int J Mol Sci | 10.3390/ijms22169064 | 2021 | |
| Pathogenicity | A Mutation Upstream of the rplN-rpsD Ribosomal Operon Downregulates Bordetella pertussis Virulence Factor Production without Compromising Bacterial Survival within Human Macrophages. | Novak J, Jurnecka D, Linhartova I, Holubova J, Stanek O, Stipl D, Dienstbier A, Vecerek B, Azevedo N, Provaznik J, Benes V, Sebo P. | mSystems | 10.1128/msystems.00612-20 | 2020 | |
| Pertussis toxin suppresses dendritic cell-mediated delivery of B. pertussis into lung-draining lymph nodes. | Klimova N, Holubova J, Streparola G, Tomala J, Brazdilova L, Stanek O, Bumba L, Sebo P. | PLoS Pathog | 10.1371/journal.ppat.1010577 | 2022 | | |
| Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins. | Lepesheva A, Osickova A, Holubova J, Jurnecka D, Knoblochova S, Espinosa-Vinals C, Bumba L, Skopova K, Fiser R, Osicka R, Sebo P, Masin J. | Sci Rep | 10.1038/s41598-021-99112-3 | 2021 | | |
| Metabolism | Bordetella pertussis Adenylate Cyclase Toxin Disrupts Functional Integrity of Bronchial Epithelial Layers. | Hasan S, Kulkarni NN, Asbjarnarson A, Linhartova I, Osicka R, Sebo P, Gudmundsson GH. | Infect Immun | 10.1128/iai.00445-17 | 2018 | |
| The rtxA toxin gene of Kingella kingae: a pertinent target for molecular diagnosis of osteoarticular infections. | Lehours P, Freydiere AM, Richer O, Burucoa C, Boisset S, Lanotte P, Prere MF, Ferroni A, Lafuente C, Vandenesch F, Megraud F, Menard A. | J Clin Microbiol | 10.1128/jcm.01657-10 | 2011 | | |
| Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes. | Arico B, Rappuoli R. | J Bacteriol | 10.1128/jb.169.6.2847-2853.1987 | 1987 | |
How to cite
If you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive139078.20260601.11
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain dataIsabel Schober, Julia Koblitz, Joaquim Sardà Carbasse, Christian Ebeling, Marvin Leon Schmidt, Adam Podstawka, Rohit Gupta, Vinodh Ilangovan, Javad Chamanara, Jörg Overmann, Lorenz Christian Reimer
Nucleic Acids Research; database issue 2025.
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