Burkholderia cenocepacia (CIP 108255, DSM 16553, ATCC BAA-245)

Name: Burkholderia cenocepacia (CIP 108255, DSM 16553, ATCC BAA-245)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 1952

Type strain

Strain Designation CF5610, J2315

Culture col. no. CIP 108255 DSM 16553 ATCC BAA-245 CCM 4899 CCUG 48434 4 more

NCBI tax ID(s) 95486

Special Collections DSMZ CCUG CIP

History DSMZ <- LMG; LMG 16656 <- J. Govan; CF5610 CIP <- 2004, CCUG <- 2003, LMG <- 1995, J. Govan, Edinburgh Univ., Edinburgh, UK: strain J2315

Links

Burkholderia cenocepacia CF5610 is an obligate aerobe, Gram-negative, motile bacterium that has multiple antibiotic resistances and was isolated from sputum from cystic fibrosis patient.

antibiotic resistance Gram-negative motile rod-shaped obligate aerobe genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 8887

LMG 16656,CCM 4899,ATCC BAA-245,NCTC 13227,CCUG 48434,DSM 16553,CBMAI 625,CIP 108255,BCRC 17448,CCRC 17448,NCPPB 4247

@ref 20215

Last LPSN update 2026-05-29 08:25:22

Domain Bacteria

Phylum Pseudomonadota

Class Betaproteobacteria

Order Burkholderiales

Family Burkholderiaceae

Genus Burkholderia

Species Burkholderia cenocepacia

Full scientific name Burkholderia cenocepacia Vandamme et al. 2003

BacDive ID	Other strains from **Burkholderia cenocepacia** (60)	Type strain
141302	B. cenocepacia CCUG 788, ATCC 25610, LMG 6986
147328	B. cenocepacia CCUG 33378, LMG 16235
147719	B. cenocepacia CCUG 34078, NCTC 13010, LMG 12614
147720	B. cenocepacia CCUG 34079, NCTC 13008, LMG 12615
147721	B. cenocepacia CCUG 34081, LMG 13011
147749	B. cenocepacia CCUG 34142
148729	B. cenocepacia CCUG 35866
148810	B. cenocepacia CCUG 35968, LMG R-922
149014	B. cenocepacia CCUG 36725
149234	B. cenocepacia CCUG 37311, LMG R1185
149293	B. cenocepacia CCUG 37432
149652	B. cenocepacia CCUG 38121
150090	B. cenocepacia CCUG 38974
150324	B. cenocepacia CCUG 39663
150458	B. cenocepacia CCUG 39988
150593	B. cenocepacia CCUG 41697
150599	B. cenocepacia CCUG 41711
150723	B. cenocepacia CCUG 42057
150771	B. cenocepacia CCUG 42262
150982	B. cenocepacia CCUG 42934
151208	B. cenocepacia CCUG 43471
151810	B. cenocepacia CCUG 44959
151842	B. cenocepacia CCUG 45036
151843	B. cenocepacia CCUG 45037
151947	B. cenocepacia CCUG 45301
152326	B. cenocepacia CCUG 46446
152337	B. cenocepacia CCUG 46467
152399	B. cenocepacia CCUG 46672
152403	B. cenocepacia CCUG 46686
153538	B. cenocepacia CCUG 50116
153539	B. cenocepacia CCUG 50121
153540	B. cenocepacia CCUG 50126
153541	B. cenocepacia CCUG 50127
153542	B. cenocepacia CCUG 50130
153544	B. cenocepacia CCUG 50133
153545	B. cenocepacia CCUG 50137
153548	B. cenocepacia CCUG 50142
153549	B. cenocepacia CCUG 50143
153635	B. cenocepacia CCUG 50452
153753	B. cenocepacia CCUG 50863
154322	B. cenocepacia CCUG 53080
154435	B. cenocepacia CCUG 53615
154635	B. cenocepacia CCUG 54660
154675	B. cenocepacia CCUG 54812
154676	B. cenocepacia CCUG 54817
154701	B. cenocepacia CCUG 54883, BCC 0231, CEP 0868, LMG 21461
154702	B. cenocepacia CCUG 54884, LMG 19230
155267	B. cenocepacia CCUG 57141
155442	B. cenocepacia CCUG 57771 B
155694	B. cenocepacia CCUG 59017
156062	B. cenocepacia CCUG 60245
156307	B. cenocepacia CCUG 61115
156327	B. cenocepacia CCUG 61179
156329	B. cenocepacia CCUG 61184
156330	B. cenocepacia CCUG 61185
156332	B. cenocepacia CCUG 61191
156401	B. cenocepacia CCUG 61583
156514	B. cenocepacia CCUG 62286
156955	B. cenocepacia CCUG 67370 Q
156973	B. cenocepacia CCUG 67839 Q

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Motility	Confidence
117244	negative	rod-shaped
125438	negative			97

Colony morphology

6505

Incubation period1-2 days

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
6505	COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)	Medium recipe at MediaDive	Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
37374	MEDIUM 72- for trypto casein soja agar		Distilled water make up to (1000.000 ml);Trypto casein soy agar (40.000 g)
6505	TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)	Medium recipe at MediaDive	Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water
117244	CIP Medium 72	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
6505	positive	growth	30
37374	positive	growth	30
117244	positive	growth	25-41
117244	negative	growth	5
117244	negative	growth	10

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
117244	obligate aerobe
125438	aerobe	91.289
125439	obligate aerobe	97.559

Antibiotic susceptibility testing

	Test 1	Test 2	Test 3	Test 4	Test 5
@ref	6505	6505	6505	6505	6505
Medium	Mueller-Hinton Agar	Mueller-Hinton Agar	Mueller-Hinton Agar	Müller-Hinton Agar	Müller-Hinton Agar
Manual annotation	1	1	1	1	1
	Inhibition zone diameter in mm	Inhibition zone diameter in mm	Inhibition zone diameter in mm	Inhibition zone diameter in mm	Inhibition zone diameter in mm
Amikacin 30µg (disc)	0	0	0	0	0
Ampicillin 10µg (disc)	0	0	0	0	0
Aztreonam 30µg (disc)	0	0	0	0	0
Bacitracin 10Unit	0	0	0	n.d.	n.d.
Cefalotin 30µg (disc)	0	0	0	n.d.	n.d.
Cefazolin 30µg (disc)	0	0	0	n.d.	n.d.
Cefiderocol 30µg (disc)	n.d.	n.d.	n.d.	40-42	50
Cefotaxime 30µg (disc)	0	0	0	0	0
Ceftazidime 10µg (disc)	n.d.	n.d.	n.d.	0	0
Ceftriaxone 30µg (disc)	0	0	0	0	0
Chloramphenicol 30µg (disc)	10	10	0	10	12
Ciprofloxacin 5µg (disc)	n.d.	n.d.	n.d.	10	14
Clindamycin 10µg (disc)	0	0	0	0	0
Colistin 10µg (disc)	0	0	0	n.d.	n.d.
Colistin sulphate 10µg (disc)	n.d.	n.d.	n.d.	0	0
Doxycycline 30µg (disc)	10	10	10	n.d.	n.d.
Erythromycin 15µg (disc)	0	0	0	0	0
Fosfomycin 50µg (disc)	0	0	0	0	0
Gentamicin 10µg (disc)	0	0	0	n.d.	n.d.
Gentamicin 30µg (disc)	n.d.	n.d.	n.d.	10	0
Imipenem 10µg (disc)	0	0	0	0	0
Kanamycin 30µg (disc)	0	0	0	0	0
Levofloxacin 5µg (disc)	n.d.	n.d.	n.d.	10	10
Lincomycin 15µg (disc)	0	0	0	n.d.	n.d.
Linezolid 10µg (disc)	0	0	0	0	0
Meropenem 10µg (disc)	n.d.	n.d.	n.d.	10-12	0
Mezlocillin 30µg (disc)	0	0	0	n.d.	n.d.
Moxifloxacin 5µg (disc)	10	0	0	6-8	6-8
Neomycin 30µg (disc)	0	0	0	n.d.	n.d.
Nitrofurantoin 100µg (disc)	0	0	0	0	0
Norfloxacin 10µg (disc)	8	0	0	n.d.	n.d.
Nystatin 100Unit	0	0	0	n.d.	n.d.
Ofloxacin 5µg (disc)	0	0	0	0	0
Oxacillin 5µg (disc)	0	0	0	0	0
Penicillin G 6µg (disc)	0	0	0	0	0
Pipemidic acid 20µg (disc)	0	0	0	n.d.	n.d.
Piperacillin/Tazobactam 40µg (disc)	0	0	0	n.d.	n.d.
Piperacillin/Tazobactam 110µg (disc)	n.d.	n.d.	n.d.	18	0
Polymyxin B 300Unit	0	0	0	0	0
Quinupristin/Dalfopristin 15µg (disc)	0	0	0	0	0
Rifampicin 5µg (disc)	n.d.	n.d.	n.d.	0	0
Teicoplanin 30µg (disc)	0	0	0	0	0
Tetracycline 30µg (disc)	8	0	6	6-8	6-8
Ticarcillin 75µg (disc)	0	0	0	0	0
Tigecycline 15µg (disc)	n.d.	n.d.	n.d.	6-8	0
Trimethoprim-sulfamethoxazole (1:19) 10µg (disc)	n.d.	n.d.	n.d.	0	0
Vancomycin 30µg (disc)	0	0	0	0	0

Spore formation

@ref	Spore formation	Confidence
125439		98.181

Halophily

@ref	Salt	Growth	Tested relation	Concentration
117244	NaCl	positive	growth	0-6 %
117244	NaCl		growth	8 %
117244	NaCl		growth	10 %

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68369	17634 ChEBI	D-glucose	+	assimilation	from API 20NE
68369	16899 ChEBI	D-mannitol	+	assimilation	from API 20NE
68369	16024 ChEBI	D-mannose	+	assimilation	from API 20NE
68369	27689 ChEBI	decanoate	+	assimilation	from API 20NE
117244	4853 ChEBI	esculin	-	hydrolysis
68369	4853 ChEBI	esculin	-	hydrolysis	from API 20NE
68369	5291 ChEBI	gelatin	-	hydrolysis	from API 20NE
68369	24265 ChEBI	gluconate	+	assimilation	from API 20NE
68369	25115 ChEBI	malate	+	assimilation	from API 20NE
68369	17306 ChEBI	maltose	-	assimilation	from API 20NE
68369	59640 ChEBI	N-acetylglucosamine	+	assimilation	from API 20NE
117244	17632 ChEBI	nitrate	-	reduction
117244	17632 ChEBI	nitrate	-	respiration
68369	17632 ChEBI	nitrate	-	reduction	from API 20NE
117244	16301 ChEBI	nitrite	-	reduction
68369	27897 ChEBI	tryptophan	-	energy source	from API 20NE

Antibiotic resistance

@ref	ChEBI	Metabolite	Resistance conc.
117244		0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)
6505	2637	Amikacin	30 µg (disc)	from Antibiotic test
6505	28971	Ampicillin	10 µg (disc)	from Antibiotic test
6505	161680	Aztreonam	30 µg (disc)	from Antibiotic test
6505	28669	Bacitracin	10 Unit	from Antibiotic test
6505	124991	Cefalotin	30 µg (disc)	from Antibiotic test
6505	474053	Cefazolin	30 µg (disc)	from Antibiotic test
6505	204928	Cefotaxime	30 µg (disc)	from Antibiotic test
6505	3508	Ceftazidime	10 µg (disc)	from Antibiotic test
6505	29007	Ceftriaxone	30 µg (disc)	from Antibiotic test
6505	3745	Clindamycin	10 µg (disc)	from Antibiotic test
6505	37943	Colistin	10 µg (disc)	from Antibiotic test
6505	37943	Colistin sulphate	10 µg (disc)	from Antibiotic test
6505	48923	Erythromycin	15 µg (disc)	from Antibiotic test
6505	28915	Fosfomycin	50 µg (disc)	from Antibiotic test
6505	17833	Gentamycin	10 µg (disc)	from Antibiotic test
6505	471744	Imipenem	10 µg (disc)	from Antibiotic test
6505	6104	Kanamycin	30 µg (disc)	from Antibiotic test
6505	6472	Lincomycin	15 µg (disc)	from Antibiotic test
6505	63607	Linezolid	10 µg (disc)	from Antibiotic test
6505	6919	Mezlocillin	30 µg (disc)	from Antibiotic test
6505	7507	Neomycin	30 µg (disc)	from Antibiotic test
6505	71415	Nitrofurantoin	100 µg (disc)	from Antibiotic test
6505	7660	Nystatin	100 Unit	from Antibiotic test
6505	7731	Ofloxacin	5 µg (disc)	from Antibiotic test
6505	7809	Oxacillin	5 µg (disc)	from Antibiotic test
6505	18208	Penicillin G	6 µg (disc)	from Antibiotic test
6505	75250	Pipemidic acid	20 µg (disc)	from Antibiotic test
6505		Piperacillin/Tazobactam	40 µg (disc)	from Antibiotic test
6505	8309	Polymyxin B	300 Unit	from Antibiotic test
6505		Quinupristin/Dalfopristin	15 µg (disc)	from Antibiotic test
6505	28077	Rifampicin	5 µg (disc)	from Antibiotic test
6505	29687	Teicoplanin	30 µg (disc)	from Antibiotic test
6505	9587	Ticarcillin	75 µg (disc)	from Antibiotic test
6505		Trimethoprim-sulfamethoxazole (1:19)	10 µg (disc)	from Antibiotic test
6505	28001	Vancomycin	30 µg (disc)	from Antibiotic test

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68369	35581 ChEBI	indole		from API 20NE
117244	35581 ChEBI	indole

Metabolite tests

@ref	Chebi-ID	Metabolite	Indole test
68369	35581 ChEBI	indole	-	from API 20NE

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
117244	alcohol dehydrogenase	-	1.1.1.1
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	-	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
117244	amylase	-
68382	beta-galactosidase	-	3.2.1.23	from API zym
117244	beta-galactosidase	+	3.2.1.23
68382	beta-glucosidase	+	3.2.1.21	from API zym
68369	beta-glucosidase	-	3.2.1.21	from API 20NE
68382	beta-glucuronidase	-	3.2.1.31	from API zym
117244	caseinase	-	3.4.21.50
117244	catalase	+	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
117244	DNase	-
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
117244	gelatinase	-
68369	gelatinase	-		from API 20NE
117244	lecithinase	-
68382	leucine arylamidase	+	3.4.11.1	from API zym
117244	lipase	+
68382	lipase (C 14)	-		from API zym
117244	lysine decarboxylase	-	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
117244	ornithine decarboxylase	-	4.1.1.17
117244	oxidase	+
117244	protease	-
68382	trypsin	-	3.4.21.4	from API zym
117244	tryptophan deaminase	-
117244	tween esterase	-
117244	urease	-	3.5.1.5
68382	valine arylamidase	-		from API zym

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
117244	-	+	+	+	-	+	-	-	-	-	+	+	-	-	-	-	+	-	-	-

API 20NE

@ref	Reduction of nitratesNO3	TRP	GLU_ Ferm	ADH (Arg)	URE	ESC	GEL	PNPG	GLU_ Assim	ARA	MNE	MAN	NAG	MAL	GNT	CAP	ADI	MLT	CIT	PAC	OX
6505	-	-	-	-	-	-	-	+	+	-	+	+	+	-	+	+	+	+	+/-	+	-
6505	-	-	-	-	-	-	-	+	+	+/-	+	+	+	-	+	+	+	+	+	+	+
6505	-	-	+/-	-	-	-	-	+	+	+/-	+	+	+	-	+	+	+	+	+	+	not determinedn.d.
6505	-	-	+	+	+	-	-	+	+	+/-	+	+	+	-	+	+	+	+	+	+	+
6505	-	-	-	-	-	-	-	+	+	+/-	+	+	+	-	+	+	+/-	+	+	+	+

API biotype100

@ref	ControlQ	D-glucose as carbon sourceGLU	D-fructose as carbon sourceFRU	D-galactose as carbon sourceGAL	D-trehalose as carbon sourceTRE	D-mannose as carbon sourceMNE	L-sorbose as carbon sourceSBE	D-melibiose as carbon sourceMEL	sucrose as carbon sourceSAC	D-raffinose as carbon sourceRAF	maltotriose as carbon sourceMTE	maltose as carbon sourceMAL	lactose as carbon sourceLAC	lactulose as carbon sourceLTE	1-O-methyl-beta-galactopyranoside as carbon sourceMbGa	1-O-methyl-alpha-galactopyranoside as carbon sourceMaGa	D-cellobiose as carbon sourceCEL	gentiobiose as carbon sourceGEN	1-O-methyl-beta-D-glucopyranoside as carbon sourceMbGu	esculin as carbon sourceESC	D-ribose as carbon sourceRIB	L-arabinose as carbon sourceARA	D-xylose as carbon sourceXYL	palatinose as carbon sourcePLE	L-rhamnose as carbon sourceRHA	L-fucose as carbon sourceFUC	D-melezitose as carbon sourceMLZ	D-arabitol as carbon sourceDARL	L-arabitol as carbon sourceLARL	xylitol as carbon sourceXLT	dulcitol as carbon sourceDUL	D-tagatose as carbon sourceTAG	glycerol as carbon sourceGLY	myo-inositol as carbon sourceINO	D-mannitol as carbon sourceMAN	maltitol as carbon sourceMTL	D-turanose as carbon sourceTUR	D-sorbitol as carbon sourceSOR	adonitol as carbon sourceADO	hydroxyquinoline-beta-glucuronide as carbon sourceHBG	D-lyxose as carbon sourceLYX	i-erythritol as carbon sourceERY	1-O-methyl-alpha-D-glucoside as carbon sourceMDG	3-O-methyl-D-glucose as carbon source3MDG	D-saccharate as carbon sourceSAT	mucate as carbon sourceMUC	L-tartrate as carbon sourceLTAT	D-tartrate as carbon sourceDTAT	meso-tartrate as carbon sourceMTAT	D-malate as carbon sourceDMLT	L-malate as carbon sourceLMLT	cis-aconitate as carbon sourceCATE	trans-aconitate as carbon sourceTATE	tricarballylate as carbon sourceTTE	citrate as carbon sourceCIT	D-glucuronate as carbon sourceGRT	D-galacturonate as carbon sourceGAT	2-ketogluconate as carbon source2KG	5-ketogluconate as carbon source5KG	tryptophan as carbon sourceTRY	N-acetyl-D-glucosamine as carbon sourceNAG	D-gluconate as carbon sourceGNT	phenylacetate as carbon sourcePAC	protocatechuate as carbon sourcePAT	4-hydroxybenzoate as carbon sourcepOBE	quinate as carbon sourceQAT	gentisate as carbon sourceGTE	3-hydroxybenzoate as carbon sourcemOBE	benzoate as carbon sourceBAT	3-phenylpropionate as carbon sourcePPAT	m-coumarate as carbon sourceCMT	trigonelline as carbon sourceTGE	betaine as carbon sourceBET	putrescine as carbon sourcePCE	4-aminobutyrate as carbon sourceABT	histamine as carbon sourceHIN	DL-lactate as carbon sourceLAT	caprate as carbon sourceCAP	caprylate as carbon sourceCYT	L-histidine as carbon sourceHIS	succinate as carbon sourceSUC	fumarate as carbon sourceFUM	glutarate as carbon sourceGRE	DL-glycerate as carbon sourceGYT	5-aminovalerate as carbon sourceAVT	ethanolamine as carbon sourceETN	tryptamine as carbon sourceTTN	D-glucosamine as carbon sourceGLN	itaconate as carbon sourceITA	3-hydroxybutyrate as carbon source3OBU	L-aspartate as carbon sourceAPT	L-glutamate as carbon sourceGTT	L-proline as carbon sourcePRO	D-alanine as carbon sourceDALA	L-alanine as carbon sourceLALA	L-serine as carbon sourceSER	malonate as carbon sourceMNT	propionate as carbon sourcePROP	L-tyrosine as carbon sourceTYR	2-ketoglutarate as carbon source2KT
117244	not determinedn.d.	+	+	+	-	+	-	-	+	-	-	-	-	-	+	-	-	-	-	-	+	+	+	-	-	+	-	+	+	+	+	-	+	+	+	-	-	+	+	-	-	-	-	-	+	+	+	-	-	+	+	+	+	+	+	+	+	+	+	-	+	+	+	+	+	+	+	+	-	-	-	-	+	-	+	-	+	+	+	-	+	+	+	+	-	+	-	+	-	+	+	+	+	+	+	+	+	+	+	+

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Infection	#Disease	#Cystic fibrosis
#Infection	#Patient	-
#Host Body Product	#Fluids	#Sputum

Isolation

@ref	Sample type	Host species	Geographic location	Country	Country ISO 3 Code	Continent	Latitude	Longitude	Sampling date	Isolation date
6505	sputum from cystic fibrosis patient	Homo sapiens	Edinburgh	United Kingdom	GBR	Europe	55.9533	-3.1883 55.9533/-3.1883
58156	Human sputum,cystic fibrosis	Homo sapiens	Edinburgh	United Kingdom	GBR	Europe			1989
117244	Human, Sputum, cystic fibrosis	Homo sapiens	Edinburgh, Scotland	United Kingdom	GBR	Europe				1989

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
6505	2	Risk group (German classification) According to TRBA 466
117244	1	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	51699_B01 assembly for Burkholderia cenocepacia NCTC13227	contig	GCA_900446215	95486.373	8109070605	95486	75.1
66792	BIG assembly for Burkholderia cepacia LMG 16656	contig	GCA_000877315	292.25	2630968810	292	52.4

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
6505	Burkholderia cepacia genomovar III 16S ribosomal RNA gene, partial sequence	AF148556	1408		95486

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: 51699_B01 assembly for Burkholderia cenocepacia NCTC13227
BV-BRC: 95486.373

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	97.56	no
125439	gram_stain	BacteriaNetⓘ	negative	88.25	no
125439	motility	BacteriaNetⓘ	yes	72.43	no
125439	spore_formation	BacteriaNetⓘ	no	98.18	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Burkholderia cenocepacia strain NCTC13227
PATRIC: 95486.373

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	97.00	no
125438	anaerobic	anaerobicⓘ	no	96.56	yes
125438	aerobic	aerobicⓘ	yes	91.29	no
125438	spore-forming	spore-formingⓘ	no	86.33	no
125438	thermophilic	thermophileⓘ	no	98.00	no
125438	flagellated	motile2+ⓘ	yes	83.34	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Cyclic di AMP phosphodiesterase nanovaccine elicits protective immunity against Burkholderia cenocepacia infection in mice.	Gawad WE, Nagy YI, Samir TM, Mansour AMI, Helmy OM.	NPJ Vaccines	10.1038/s41541-025-01074-4	2025
Pathogenicity	BpeB, a major resistance-nodulation-cell division transporter from Burkholderia cenocepacia: construct design, crystallization and preliminary structural analysis.	Horikawa T, Hung LW, Kim HB, Shaya D, Kim CY, Terwilliger TC, Yamashita E, Aoki M, Okada U, Murakami S.	Acta Crystallogr F Struct Biol Commun	10.1107/s2053230x18013547	2018
Metabolism	Effects of Halide Ions on the Carbamidocyclophane Biosynthesis in Nostoc sp. CAVN2.	Preisitsch M, Heiden SE, Beerbaum M, Niedermeyer TH, Schneefeld M, Herrmann J, Kumpfmuller J, Thurmer A, Neidhardt I, Wiesner C, Daniel R, Muller R, Bange FC, Schmieder P, Schweder T, Mundt S.	Mar Drugs	10.3390/md14010021	2016
	Effective therapeutic strategies against Pseudomonas aeruginosa and Burkholderia Cepacia complex infections.	Helmy NAM, Basyony AF, Tohamy STK, Zaki SA.	Sci Rep	10.1038/s41598-025-26712-8	2025
	Burkholderia cenocepacia and Pseudomonas aeruginosa in dual-species models: Insights into population distribution, antibiotic susceptibility, and virulence.	Alcacer-Almansa J, Blanco-Cabra N, Torrents E.	Virulence	10.1080/21505594.2025.2494039	2025
Pathogenicity	Broken beyond repair: TA system ParE toxins mediate effective gyrase inhibition without driving resistance.	Tu C-H, Ruan S, Holt M, Bourne CR.	J Bacteriol	10.1128/jb.00416-24	2025
Genetics	Whole genome comparisons reveal gut-to-lung translocation of Escherichia coli and Burkholderia cenocepacia in two cases of ventilator-associated pneumonia in ICU patients.	Gao H, Xu L, Liu Y, Wang X, Zhu S, Lin H, Gao Y, Mao D, Lu X, Luo Y.	Respir Res	10.1186/s12931-025-03204-x	2025
	Soleris® Automated System for the Rapid Detection of Burkholderia cepacia Complex in Cosmetic Products.	Zhang L, Tolan J, Lavigne N, Montei C, Donofrio R, Biswas P.	J AOAC Int	10.1093/jaoacint/qsac109	2022
	A High-Throughput Microtiter Plate Screening Assay to Quantify and Differentiate Species in Dual-Species Biofilms.	Campo-Perez V, Alcacer-Almansa J, Julian E, Torrents E.	Microorganisms	10.3390/microorganisms11092244	2023
	SSNOMBACTER: A collection of scattering-type scanning near-field optical microscopy and atomic force microscopy images of bacterial cells.	Lucidi M, Tranca DE, Nichele L, Unay D, Stanciu GA, Visca P, Holban AM, Hristu R, Cincotti G, Stanciu SG.	Gigascience	10.1093/gigascience/giaa129	2020
Genetics	A Phylogeny-Informed Proteomics Approach for Species Identification within the Burkholderia cepacia Complex.	Wang H, Cisse OH, Bolig T, Drake SK, Chen Y, Strich JR, Youn JH, Okoro U, Rosenberg AZ, Sun J, LiPuma JJ, Suffredini AF, Dekker JP.	J Clin Microbiol	10.1128/jcm.01741-20	2020
	Aspartate alpha-decarboxylase a new therapeutic target in the fight against Helicobacter pylori infection.	Ibrahim KA, Kashef MT, Elkhamissy TR, Ramadan MA, Helmy OM.	Front Microbiol	10.3389/fmicb.2022.1019666	2022
	Methyl-hydroxylamine as an efficacious antibacterial agent that targets the ribonucleotide reductase enzyme.	Julian E, Baelo A, Gavalda J, Torrents E.	PLoS One	10.1371/journal.pone.0122049	2015
Pathogenicity	Antimicrobial activity of essential oils against multidrug-resistant clinical isolates of the Burkholderia cepacia complex.	Vasireddy L, Bingle LEH, Davies MS.	PLoS One	10.1371/journal.pone.0201835	2018
	A Novel Loop-Mediated Isothermal Amplification Assay for Rapid Detection of Yersinia pestis.	Bai Y, Rizzo MR, Parise C, Maes S, Eisen RJ.	Front Microbiol	10.3389/fmicb.2022.863142	2022
Pathogenicity	Evaluation of combination therapy for Burkholderia cenocepacia lung infection in different in vitro and in vivo models.	Van den Driessche F, Vanhoutte B, Brackman G, Crabbe A, Rigole P, Vercruysse J, Verstraete G, Cappoen D, Vervaet C, Cos P, Coenye T.	PLoS One	10.1371/journal.pone.0172723	2017
Metabolism	An ERp57-mediated disulphide exchange promotes the interaction between Burkholderia cenocepacia and epithelial respiratory cells.	Pacello F, D'Orazio M, Battistoni A.	Sci Rep	10.1038/srep21140	2016
	Development of a quadruplex PCR amplicon next generation sequencing assay for detection and differentiation of Bartonella spp.	Bai Y, Osikowicz LM, Hojgaard A, Eisen RJ.	Front Microbiol	10.3389/fmicb.2023.1243471	2023
	Application of qPCR assays based on haloacids transporter gene dehp2 for discrimination of Burkholderia and Paraburkholderia.	Su X, Shi Y, Li R, Lu ZN, Zou X, Wu JX, Han ZG.	BMC Microbiol	10.1186/s12866-019-1411-0	2019
Pathogenicity	In vitro activity of N-acetylcysteine against Stenotrophomonas maltophilia and Burkholderia cepacia complex grown in planktonic phase and biofilm.	Pollini S, Di Pilato V, Landini G, Di Maggio T, Cannatelli A, Sottotetti S, Cariani L, Aliberti S, Blasi F, Sergio F, Rossolini GM, Pallecchi L.	PLoS One	10.1371/journal.pone.0203941	2018
	[⁶⁸Ga]Ga-Ornibactin for Burkholderia cepacia complex Infection Imaging Using Positron Emission Tomography.	Bendova K, Raclavsky V, Novotny R, Luptakova D, Popper M, Novy Z, Hajduch M, Petrik M.	J Med Chem	10.1021/acs.jmedchem.3c00469	2023
Pathogenicity	Extracellular glutathione decreases the ability of Burkholderia cenocepacia to penetrate into epithelial cells and to induce an inflammatory response.	D'Orazio M, Pacello F, Battistoni A.	PLoS One	10.1371/journal.pone.0047550	2012
Metabolism	Intra- and Interspecies Effects of Outer Membrane Vesicles from Stenotrophomonas maltophilia on beta-Lactam Resistance.	Devos S, Stremersch S, Raemdonck K, Braeckmans K, Devreese B.	Antimicrob Agents Chemother	10.1128/aac.02171-15	2016
Pathogenicity	Targeting the Nonmevalonate Pathway in Burkholderia cenocepacia Increases Susceptibility to Certain beta-Lactam Antibiotics.	Sass A, Everaert A, Van Acker H, Van den Driessche F, Coenye T.	Antimicrob Agents Chemother	10.1128/aac.02607-17	2018
	Burkholderia cenocepacia Infections in Cystic Fibrosis Patients: Drug Resistance and Therapeutic Approaches.	Scoffone VC, Chiarelli LR, Trespidi G, Mentasti M, Riccardi G, Buroni S.	Front Microbiol	10.3389/fmicb.2017.01592	2017
Pathogenicity	Various Evolutionary Trajectories Lead to Loss of the Tobramycin-Potentiating Activity of the Quorum-Sensing Inhibitor Baicalin Hydrate in Burkholderia cenocepacia Biofilms.	Sass A, Slachmuylders L, Van Acker H, Vandenbussche I, Ostyn L, Bove M, Crabbe A, Chiarelli LR, Buroni S, Van Nieuwerburgh F, Abatih E, Coenye T.	Antimicrob Agents Chemother	10.1128/aac.02092-18	2019
	Effect of beta-Lactamase inhibitors on in vitro activity of beta-Lactam antibiotics against Burkholderia cepacia complex species.	Everaert A, Coenye T.	Antimicrob Resist Infect Control	10.1186/s13756-016-0142-3	2016
	Open Database Searching Enables the Identification and Comparison of Bacterial Glycoproteomes without Defining Glycan Compositions Prior to Searching.	Ahmad Izaham AR, Scott NE.	Mol Cell Proteomics	10.1074/mcp.tir120.002100	2020
Metabolism	In Vitro Evaluation of Antimicrobial Peptides from the Black Soldier Fly (Hermetia Illucens) against a Selection of Human Pathogens.	Van Moll L, De Smet J, Paas A, Tegtmeier D, Vilcinskas A, Cos P, Van Campenhout L.	Microbiol Spectr	10.1128/spectrum.01664-21	2022
Metabolism	The Small RNA ncS35 Regulates Growth in Burkholderia cenocepacia J2315.	Kiekens S, Sass A, Van Nieuwerburgh F, Deforce D, Coenye T.	mSphere	10.1128/msphere.00579-17	2018
Metabolism	Biogenic selenium nanoparticles synthesized by Stenotrophomonas maltophilia SeITE02 loose antibacterial and antibiofilm efficacy as a result of the progressive alteration of their organic coating layer.	Cremonini E, Boaretti M, Vandecandelaere I, Zonaro E, Coenye T, Lleo MM, Lampis S, Vallini G.	Microb Biotechnol	10.1111/1751-7915.13260	2018
	Genetic Determinants Associated With in Vivo Survival of Burkholderia cenocepacia in the Caenorhabditis elegans Model.	Wong YC, Abd El Ghany M, Ghazzali RNM, Yap SJ, Hoh CC, Pain A, Nathan S.	Front Microbiol	10.3389/fmicb.2018.01118	2018
	A Review of the Antibacterial, Fungicidal and Antiviral Properties of Selenium Nanoparticles.	Serov DA, Khabatova VV, Vodeneev V, Li R, Gudkov SV.	Materials (Basel)	10.3390/ma16155363	2023
Pathogenicity	Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo.	Brackman G, Cos P, Maes L, Nelis HJ, Coenye T.	Antimicrob Agents Chemother	10.1128/aac.00045-11	2011
Pathogenicity	Antibacterial activity of a lectin-like Burkholderia cenocepacia protein.	Ghequire MG, De Canck E, Wattiau P, Van Winge I, Loris R, Coenye T, De Mot R.	Microbiologyopen	10.1002/mbo3.95	2013
Genetics	Genome-wide transcription start site profiling in biofilm-grown Burkholderia cenocepacia J2315.	Sass AM, Van Acker H, Forstner KU, Van Nieuwerburgh F, Deforce D, Vogel J, Coenye T.	BMC Genomics	10.1186/s12864-015-1993-3	2015
Pathogenicity	Molecular mechanisms of chlorhexidine tolerance in Burkholderia cenocepacia biofilms.	Coenye T, Van Acker H, Peeters E, Sass A, Buroni S, Riccardi G, Mahenthiralingam E.	Antimicrob Agents Chemother	10.1128/aac.01571-10	2011
	1-Aminocyclopropane-1-carboxylate deaminase producers associated to maize and other Poaceae species.	Bouffaud ML, Renoud S, Dubost A, Moenne-Loccoz Y, Muller D.	Microbiome	10.1186/s40168-018-0503-7	2018
Metabolism	Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction.	Fang K, Zhao H, Sun C, Lam CM, Chang S, Zhang K, Panda G, Godinho M, Martins dos Santos VA, Wang J.	BMC Syst Biol	10.1186/1752-0509-5-83	2011
Pathogenicity	Identification of a novel virulence factor in Burkholderia cenocepacia H111 required for efficient slow killing of Caenorhabditis elegans.	Huber B, Feldmann F, Kothe M, Vandamme P, Wopperer J, Riedel K, Eberl L.	Infect Immun	10.1128/iai.72.12.7220-7230.2004	2004
Metabolism	VOC fingerprints: metabolomic signatures of biothreat agents with and without antibiotic resistance.	Dailey A, Saha J, Zaidi F, Abdirahman H, Haymond A, Alem F, Hakami R, Couch R.	Sci Rep	10.1038/s41598-020-68622-x	2020
Metabolism	Biofilm-grown Burkholderia cepacia complex cells survive antibiotic treatment by avoiding production of reactive oxygen species.	Van Acker H, Sass A, Bazzini S, De Roy K, Udine C, Messiaen T, Riccardi G, Boon N, Nelis HJ, Mahenthiralingam E, Coenye T.	PLoS One	10.1371/journal.pone.0058943	2013
Genetics	The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients.	Holden MT, Seth-Smith HM, Crossman LC, Sebaihia M, Bentley SD, Cerdeno-Tarraga AM, Thomson NR, Bason N, Quail MA, Sharp S, Cherevach I, Churcher C, Goodhead I, Hauser H, Holroyd N, Mungall K, Scott P, Walker D, White B, Rose H, Iversen P, Mil-Homens D, Rocha EP, Fialho AM, Baldwin A, Dowson C, Barrell BG, Govan JR, Vandamme P, Hart CA, Mahenthiralingam E, Parkhill J.	J Bacteriol	10.1128/jb.01230-08	2009
	Transcriptional response of Burkholderia cenocepacia J2315 sessile cells to treatments with high doses of hydrogen peroxide and sodium hypochlorite.	Peeters E, Sass A, Mahenthiralingam E, Nelis H, Coenye T.	BMC Genomics	10.1186/1471-2164-11-90	2010
Pathogenicity	Investigating the Role of the Host Multidrug Resistance Associated Protein Transporter Family in Burkholderia cepacia Complex Pathogenicity Using a Caenorhabditis elegans Infection Model.	Tedesco P, Visone M, Parrilli E, Tutino ML, Perrin E, Maida I, Fani R, Ballestriero F, Santos R, Pinilla C, Di Schiavi E, Tegos G, de Pascale D.	PLoS One	10.1371/journal.pone.0142883	2015
Pathogenicity	Biocide susceptibility of the Burkholderia cepacia complex.	Rose H, Baldwin A, Dowson CG, Mahenthiralingam E.	J Antimicrob Chemother	10.1093/jac/dkn540	2009
Metabolism	Distribution and properties of the genes encoding the biosynthesis of the bacterial cofactor, pyrroloquinoline quinone.	Shen YQ, Bonnot F, Imsand EM, RoseFigura JM, Sjolander K, Klinman JP.	Biochemistry	10.1021/bi201763d	2012
	The medicinal applications of imidazolium carbene-metal complexes.	Hindi KM, Panzner MJ, Tessier CA, Cannon CL, Youngs WJ.	Chem Rev	10.1021/cr800500u	2009
Phylogeny	Development of a species-specific fur gene-based method for identification of the Burkholderia cepacia complex.	Lynch KH, Dennis JJ, Dennis JJ.	J Clin Microbiol	10.1128/jcm.01460-07	2008
Pathogenicity	New Perspectives on the Use of Phytochemicals as an Emergent Strategy to Control Bacterial Infections Including Biofilms.	Borges A, Abreu AC, Dias C, Saavedra MJ, Borges F, Simoes M.	Molecules	10.3390/molecules21070877	2016
	Playing with Structural Parameters in the Design of Ruthenium(II)-p-Cymene Complexes as Potential Antibacterial Agents.	Giacomazzo GE, Ceccherini V, Vitali V, Conti L, Vaccaro F, Coscione F, Perrin E, Fondi M, Massai L, Giorgi C, Messori L.	Inorg Chem	10.1021/acs.inorgchem.5c03505	2025
	Outbreak of Burkholderia cepacia complex infection associated with intrinsically contaminated commercial 0.5% chlorhexidine solution.	Dilokkunanant T, Malathum K, Chotiprasitsakul D, Santanirand P, Muntajit T, Techasaensiri C.	J Hosp Infect	10.1016/j.jhin.2025.09.019	2025
	Burkholderia cenocepacia Keratitis With Exogenous Endopthalmitis: A Complex Combination.	Bahaman Shah NS, Rosli AH, Mohd Kamal K, Nordin MF.	Cureus	10.7759/cureus.95387	2025
	Deferiprone inhibits virulence and biofilm formation in Burkholderia cenocepacia.	Ding ZW, Xu KZ, Dar OI, Yin LJ, Wang YJ, Liao YT, Wang P, Jia AQ.	Med Microbiol Immunol	10.1007/s00430-025-00824-4	2025
	Real-time investigation of a Burkholderia cenocepacia bacteraemia outbreak in a Vietnamese intensive care unit.	Nguyen ATK, Phuong Linh VK, Huong DT, Kieu PT, Phat VV, Tuyen HT, Nguyen Q, Hien NH, Diem Trinh NT, Hon HN, Binh NT, Phuong Thao PT, Quang T, Thu Van NT, Ngoc Lan PT, Mo Y, Paterson DL, Thwaites G, Thwaites L, Duy PT.	J Hosp Infect	10.1016/j.jhin.2025.04.003	2025
	Burkholderia cenocepacia outbreak linked to taps in a neonatal intensive care unit.	Purcell R, Ryan S, Meyer J, Cisera K, Sherry NL, Stewart A, Rindt A, Korman TM, Stuart RL.	Infect Dis Health	10.1016/j.idh.2024.08.001	2025
Metabolism	Structural and kinetic analysis of distinct active and inactive states of Burkholderia cenocepacia orotate phosphoribosyltransferase.	Sharma N, Turlington ZR, Zupko SP, Catoggio MN, Lukacs CM, Serbzhinskiy D, Abendroth J, Edwards TE, Lorimer DD, Barrera G, Willis S, Beyer O, Toay S, Da Li T, Torelli AT, Hicks KA, French JB.	Arch Biochem Biophys	10.1016/j.abb.2025.110332	2025
Genetics	Complete genome sequence of Burkholderia cenocepacia bacteriophage Karil-mokiny-1.	Canning JS, Ling K-M, Laucirica DR, Iszatt JJ, Stick SM, Kicic A, Phage WA.	Microbiol Resour Announc	10.1128/mra.00306-25	2025
	Structural and Conformational Analysis and Biological Activity of Adamantyl-Based Acyl-Thioureas Bearing Trihalophenyl Substituents.	Nossa Gonzalez DL, Gomez Castano JA, Saeed A, Echeverria GA, Piro OE, Lamberti YA, Erben MF.	Chempluschem	10.1002/cplu.202500311	2025
	Acute interstitial pancreatitis with Burkholderia cenocepacia pseudocyst in an immunocompetent host: A case report on an atypical presentation and review of literature.	Thaker S, Acharya RV, Banerjee B, Shridhar M, Ramamoorthi K, Kini K Y.	IDCases	10.1016/j.idcr.2025.e02291	2025
	An engineered peptide derived from the innate immune effector high-mobility group box 1 disrupts and prevents dual-genera biofilms formed by common respiratory tract pathogens.	Rhodes JD, Kelly TJ, Goodman SD, Bakaletz LO.	FEMS Microbiol Lett	10.1093/femsle/fnaf029	2025
	Achieving High Affinity for a Bacterial Lectin with Reversible Covalent Ligands.	Antonini G, Bernardi A, Gillon E, Dal Corso A, Civera M, Belvisi L, Varrot A, Mazzotta S.	J Med Chem	10.1021/acs.jmedchem.4c01876	2024
	In vitro untargeted polar metabolomics data from B. cenocepacia and S. aureus biofilm supernatants.	Skaggs H, Yoder-Himes DR.	Microbiol Resour Announc	10.1128/mra.00261-25	2025
Enzymology	Outbreak of Burkholderia cenocepacia in an intensive care unit of a tertiary care hospital identified by pulsed-field gel electrophoresis.	Kumaresan M, Manoharan M, Sugumar M, Sistla S.	Indian J Med Microbiol	10.1016/j.ijmmb.2024.100655	2024
Genetics	Burkholderia cenocepacia ST-250 in cystic fibrosis patients in Switzerland: Genomic investigation of transmission routes.	Zbinden A, Seth-Smith HMB, Beltrami V, Mancini S, Droz S, Burgi U, Melillo D, Schuurmans MM, Schwizer B, Schmid I, Casaulta C, Barben J, Mueller NJ, Imkamp F.	Diagn Microbiol Infect Dis	10.1016/j.diagmicrobio.2024.116429	2024
Phylogeny	Phylogeny, Synteny, and Distribution of Type III Secretion Systems in Burkholderia cenocepacia: A Closer Look Into Host Span.	Cordeiro GT, de Oliveira HL, Mariano DCO, Torres YS, Dias GM, Neves BC.	Microbiologyopen	10.1002/mbo3.70101	2025
	Association between Cystic Fibrosis and Pericardial Calcification Detected at Chest CT in Adults.	Rodriguez-Takeuchi S, Tullis E, Babaei Jandaghi A, Yan AT, Colak E, Hall DA, Wong K, Jimenez-Juan L, McIntyre K, Sykes J, Deva DP, Callejas MF.	Radiology	10.1148/radiol.241793	2025
	Antibacterial activity of gallic acid and methyl gallate against emerging non-fermenting bacilli.	Flores-Maldonado O, Davila-Avina J, Gonzalez GM, Becerril-Garcia MA, Rios-Lopez AL.	Folia Microbiol (Praha)	10.1007/s12223-024-01182-z	2025
	Burkholderia Cenocepacia MALDI-ToF Mass Spectra in the Assessing the Course of Lower Respiratory Tract Infection in Patients with Cystic Fibrosis.	Kondratenko OV, Sizova AI, Ereshchenko AA, Kozlov AV, Ismatullin DD, Lyamin AV, Sustretov AS.	Indian J Microbiol	10.1007/s12088-024-01366-8	2025
	Should Antimicrobial Resistance Limit Access to an Organ Transplant?	Courtwright A.	AMA J Ethics	10.1001/amajethics.2024.367	2024
Genetics	Comparative genomic analysis and characterization of novel high-quality draft genomes from the coal metagenome.	Achudhan AB, Saleena LM.	World J Microbiol Biotechnol	10.1007/s11274-024-04174-w	2024
	Regulation of Burkholderia cenocepacia virulence by the fatty acyl-CoA ligase DsfR as a response regulator of quorum sensing signal.	Li X, Song S, Kong X, Chen X, Zhao Z, Lin Z, Jia Y, Zhang Y, Luo HB, Wang QP, Zhang LH, Qian W, Deng Y.	Cell Rep	10.1016/j.celrep.2024.114223	2024
	The Bep gene cluster in Burkholderia cenocepacia H111 codes for a water-insoluble exopolysaccharide essential for biofilm formation	Bellich B, Teran LC, Fazli MM, Berti F, Rizzo R, Tolker-Nielsen T, Cescutti P.	Carbohydrate polymers.		2024
	The risk of contaminated ultrasound gels in the intensive care unit: lessons from an outbreak of Burkholderia cenocepacia.	Ahamed Sha B, Tambyah PA, Poh Li S, Rethenam S, Alenton LS, Chee Poh L, Sun Yong Y, Sii Yong P, Yan Zherong G, Ratnayake L, Ang M, Chua G, Pada SK.	Antimicrob Steward Healthc Epidemiol	10.1017/ash.2025.182	2025
Enzymology	The bacterial tRNA-modifying enzyme tRNA^Ile lysidine synthetase is genetically conserved but catalytically variable.	Muraski MJ, Guinto FC, Nilsson EM, Dabdoub JB, Robinson SC, Jiang Y, Shen Z, Alexander RW.	J Biol Chem	10.1016/j.jbc.2025.110688	2025
	Diving deep for the needle in the haystack: An outbreak investigation of Burkholderia cenocepacia bacteremia.	Ghafur A, Balaguru P, Ramanan SG, Rajendranath R, Raj R, Zehran M, Raja T, Easow JM, Srinivasan S, Devaprasad D, Sukumar T, Nilgar P, Sakthivel K, Nirumal RM, Chandra K, Lakshmi SV, Sethuraman N, Devi Bakthavatchalam Y, Veeraraghavan B.	Infect Control Hosp Epidemiol	10.1017/ice.2023.241	2024
	Species distribution and antimicrobial susceptibility of Burkholderia cepacia complex isolates in clinical infections: Experience from a tertiary care hospital, Southern India.	Kumaresan M, Manoharan M, Sugumar M, Sistla S.	Indian J Med Microbiol	10.1016/j.ijmmb.2024.100613	2024
	Tyramine, one quorum sensing inhibitor, reduces pathogenicity and restores tetracycline susceptibility in Burkholderia cenocepacia.	Yin L, Wang Y, Xiang S, Xu K, Wang B, Jia AQ.	Biochem Pharmacol	10.1016/j.bcp.2023.115906	2023
	Tension pyopneumothorax caused by Burkholderia cenocepacia: a rare case report in an immunocompetent individual.	Garg S, Mohapatra M, George Joseph C, Bhaskar M.	Monaldi Arch Chest Dis	10.4081/monaldi.2023.2616	2023
	A Nosocomial Outbreak of Burkholderia cepacia complex Linked to Contaminated Intravenous Medications in a Tertiary Care Hospital	Karakoc Parlayan H, Aksoy F, Ozdemir M, Ozkaya E, Yilmaz G.	Antibiotics (Basel)		2025
	Accumulation and ecological risk assessment of diazinon in surface sediments of Baiyangdian lake and its potential impact on probiotics and pathogens.	Wang Y, Xiao R, Hu Y, Li J, Guo C, Zhang L, Zhang K, Jorquera MA, Pan W.	Environ Pollut	10.1016/j.envpol.2024.124408	2024
Pathogenicity	Exploring phage-host interactions in Burkholderia cepacia complex bacterium to reveal host factors and phage resistance genes using CRISPRi functional genomics and transcriptomics.	Diaz B, Krishna R, Schoeniger JS, Mageeney CM.	Microbiol Spectr	10.1128/spectrum.01936-25	2025
	A case of localized paranasal sinusitis associated with Burkholderia cenocepacia ST 1880 in a cystic fibrosis patient	Kondratenko O, Lyamin A, Savinova T, Bocharova Y, Vasilyeva E, Chebotar I.	Heliyon.		2023
	Development of a qPCR detection approach for pathogenic Burkholderia cenocepacia associated with fresh vegetables.	Liu A, Phillips K, Jia J, Deng P, Zhang D, Chang S, Lu SE.	Food Microbiol	10.1016/j.fm.2023.104333	2023
Phylogeny	Bioprospecting Study of Plant Growth Promoting Rhizospheric Bacteria from Oil Palm Plantation as Biological Control Agent of Ganoderma boninense.	Yurnaliza Y, Nurwahyuni I, Lenny S, Lutfia A.	Pak J Biol Sci	10.3923/pjbs.2024.256.267	2024
	Synthesis and evaluation of aromatic BDSF bioisosteres on biofilm formation and colistin sensitivity in pathogenic bacteria.	Gomez AC, Horgan C, Yero D, Bravo M, Daura X, O'Driscoll M, Gibert I, O'Sullivan TP.	Eur J Med Chem	10.1016/j.ejmech.2023.115819	2023
	Development of a qPCR detection approach for pathogenic Burkholderia cenocepacia associated with fresh vegetables	Liu A, Phillips K, Jia J, Deng P, Zhang D, Chang S, Lu SE.	Food Microbiology.		2023
Enzymology	Crystal structure of a short-chain dehydrogenase from Burkholderia cenocepacia J2315 in complex with NADP+ and benzoic acid	Belfon K, Beyer O, Abendroth J, Dranow D, Lorimer D, Abramov A, Latimore Y, Hamilton C, Dawkins A, Hinojosa I, Martinez X, Mirabel S, Duncan M, Womack R, Hicks L, Turlington Z, Edwards T, Torelli A, Hicks K, French J.	Acta Crystallogr F Struct Biol Commun		2024
	Case Report: The Conundrum of What to Pick? Antibiotic Susceptibility Variability in Burkholderia cenocepacia in Cystic Fibrosis: Implications for Antibiotic Susceptibility Testing and Treatment.	Moore JE, McCaughan J, Rendall JC, Millar BC.	Br J Biomed Sci	10.3389/bjbs.2024.12749	2024
	Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight Pseudomonas aeruginosa-Burkholderia cenocepacia Infections: A Biophysical Study.	Antonini G, Fares M, Hauck D, Mala P, Gillon E, Belvisi L, Bernardi A, Titz A, Varrot A, Mazzotta S.	J Med Chem	10.1021/acs.jmedchem.5c00405	2025
	The Siderophore Phymabactin Facilitates the Growth of the Legume Symbiont Paraburkholderia phymatum in Aluminium-Rich Martian Soil.	Golaz D, Burgi L, Egli M, Bigler L, Pessi G.	Life (Basel)	10.3390/life15071044	2025
	Polyphosphate Kinase from Burkholderia cenocepacia, One Enzyme Catalyzing a Two-Step Cascade Reaction to Synthesize ATP from AMP.	Monterrey DT, Azcona L, Revuelta J, Sanchez-Moreno I, Garcia-Junceda E.	Int J Mol Sci	10.3390/ijms252312995	2024
	Clinical Characteristics of Patients Who Acquired Gram-Negative Bacteria During Ceftazidime-Avibactam Therapy.	Chuang C, Kao TC, Juan CH, Chou SH, Ho YC, Liu SY, Huang YR, Ho HL, Lin YT.	Infect Dis Ther	10.1007/s40121-025-01126-1	2025
	Stenotrophomonas maltophilia complex: A broadly distributed emerging pathogen.	Crisan CV, Goldberg JB.	PLoS Pathog	10.1371/journal.ppat.1013422	2025
Pathogenicity	Unraveling Burkholderia cenocepacia H111 fitness determinants using two animal models.	Paszti S, Gualdi S, Torres M, Augusto L, Harrison F, Eberl L.	mSystems	10.1128/msystems.01354-24	2025
	Advances in mitochondrial DNA base editing technology.	Song RJ, Han L, Sun HF, Shen B.	Yi Chuan	10.16288/j.yczz.23-045	2023
Proteome	N-Glycoproteomics of the Apicomplexan Parasite Toxoplasma gondii.	Horn V, Zarnovican P, Tiemann B, Pich A, Bakker H, Routier FH.	Proteomics	10.1002/pmic.202400239	2025
	Stress-hardening behaviour of biofilm streamers.	Savorana G, Redaelli T, Truzzolillo D, Cipelletti L, Secchi E.	Nat Commun	10.1038/s41467-025-64557-x	2025
Enzymology	Insights into the diverse roles of the terminal oxidases in Burkholderia cenocepacia H111.	Paszti S, Biner O, Liu Y, Bolli K, Jeggli SD, Pessi G, Eberl L.	Sci Rep	10.1038/s41598-025-86211-8	2025
	Deciphering the recent trends in pesticide bioremediation using genome editing and multi-omics approaches: a review	Hassan S, Ganai BA.	World J Microbiol Biotechnol.		2023
	How long do pathogens persist and survive in water? A systematic review.	Sosah FK, Odoom A, Anim-Baidoo I, Donkor ES.	Front Microbiol	10.3389/fmicb.2025.1654785	2025
	Mutations Affecting Cellular Levels of Cobalamin (Vitamin B₁₂) Confer Tolerance to Bactericidal Antibiotics in Burkholderia cenocepacia.	Lee D, Park J, Kim HS.	J Microbiol Biotechnol	10.4014/jmb.2406.06028	2024
Genetics	Characterization of the Antibiotic and Copper Resistance of Emergent Species of Onion-Pathogenic Burkholderia Through Genome Sequence Analysis and High-Throughput Sequencing of Differentially Enriched Random Transposon Mutants.	Padilla JJ, da Gama MAS, Barphagha I, Ham JH.	Pathogens	10.3390/pathogens14030226	2025
	Are Burkholderia Emerging Pathogens in patients with underlying morbidity: A case series.	Kumari S, Banu M, Ramanatha K, Barani R, Sridharan KS.	Heliyon	10.1016/j.heliyon.2024.e33283	2024
	The mntH gene of Burkholderia cenocepacia influences motility and quorum sensing to control virulence.	Yang C, Cui C, Deng F.	Braz J Microbiol	10.1007/s42770-024-01506-8	2024
Genetics	Deciphering the recent trends in pesticide bioremediation using genome editing and multi-omics approaches: a review.	Hassan S, Ganai BA.	World J Microbiol Biotechnol	10.1007/s11274-023-03603-6	2023
	rBC2LCN-reactive SERPINA3 is a glycobiomarker candidate for pancreatic ductal adenocarcinoma.	Mawaribuchi S, Shimomura O, Oda T, Hiemori K, Shimizu K, Yamase K, Date M, Tateno H.	Glycobiology	10.1093/glycob/cwad009	2023
	Successful Management of Recurrent Pyothorax in a Cat: Clinical Findings with Medical and Surgical Approaches.	Jang H, Kim S, Lee Y, Park J, Kwon H, Kim S, Sohn J, Kim JI, Jung DI.	Animals (Basel)	10.3390/ani15091253	2025
Genetics	Comparative Genomics Identified PenR E151V Substitution Associated with Carbapenem-Resistance Burkholderia cepacia Complex and a Novel Burkholderia cepacia Complex Specific OXA-1043 Subgroup.	Liao YC, Huang YT, Tseng CH, Liu CW, Liu PY.	Infect Drug Resist	10.2147/idr.s418969	2023
	Mutation of hmgA, encoding homogentisate 1,2-dioxygenase, is responsible for pyomelanin production but does not impact the virulence of Burkholderia cenocepacia in a chronic granulomatous disease mouse lung infection.	Moustafa DA, Wu L, Ivey M, Fankhauser SC, Goldberg JB.	Microbiol Spectr	10.1128/spectrum.00410-24	2024
	A case of localized paranasal sinusitis associated with Burkholderia cenocepacia ST 1880 in a cystic fibrosis patient.	Kondratenko O, Lyamin A, Savinova T, Bocharova Y, Vasilyeva E, Chebotar I.	Heliyon	10.1016/j.heliyon.2023.e16618	2023
	The anti-virulence activity of the non-mevalonate pathway inhibitor FR900098 towards Burkholderia cenocepacia is maintained during experimental evolution.	Bove M, Coenye T.	Microbiology (Reading)	10.1099/mic.0.001170	2022
	Burkholderia cenocepacia-mediated inhibition of Staphylococcus aureus growth and biofilm formation.	Brandt TJ, Skaggs H, Hundley T, Yoder-Himes DR.	J Bacteriol	10.1128/jb.00116-23	2025
	Anesthetic Management and Considerations for Cesarean Delivery in a Patient With Cystic Fibrosis.	Pham R, Mehdizadeh C, Baker C, Soloniuk LJ, Pasca I, Sinha A.	Case Rep Anesthesiol	10.1155/cria/6388254	2025
	A study on the occurrence of Burkholderia cepacia complex in ultrasound gels used in different veterinary clinical settings in India.	Karthikeyan R, Agri H, Yadav A, Jayakumar V, Kiranmayee B, Karikalan M, Chandra M, Lyngdoh V, Ghatak S, Sinha DK, Singh BR.	Vet Res Commun	10.1007/s11259-023-10091-4	2023
	Workflow for Identification of Burkholderia pseudomallei Clinical Isolates in Myanmar.	Aung NM, Su KK, Chantratita N, Tribuddharat C.	Jpn J Infect Dis	10.7883/yoken.jjid.2022.508	2023
	In Silico and In Vitro Analysis of Helicobacter pullorum Type Six Secretory Protein Hcp and Its Role in Bacterial Invasion and Pathogenesis.	Javed K, Gul F, Abbasi R, Batool S, Noreen Z, Bokhari H, Javed S.	Curr Microbiol	10.1007/s00284-022-02892-8	2022
	The late-stage steps of Burkholderia cenocepacia protein O-linked glycan biosynthesis are conditionally essential.	Jebeli L, McDaniels TA, Ho DTT, Tahir H, Kai-Ming NL, Mcgaw M, Karlic KI, Lewis JM, Scott NE.	J Biol Chem	10.1016/j.jbc.2025.108515	2025
	Burkholderia pseudomallei in Colombia: Laboratory Approaches to Enhance Diagnostic Accuracy.	Morales-Lopez S, Villero Wolf Y, Lechuga D, Caicedo L, Acosta Triana Y, Gomez L, Ramirez LR, Narvaez L, Pinzon H, Esquea K, Barros R, Martinez Ramos P, Marin A, Parra CM.	Int J Microbiol	10.1155/ijm/7148191	2025
	Surveillance of Multidrug-Resistant Organisms and Trends in Antimicrobial Susceptibility in Chronically Hospitalized Pediatric Patients.	Cho YK, Kim YJ, Park SY, Kang HM.	Infect Chemother	10.3947/ic.2025.0049	2025
	Genome-wide analysis of Burkholderia for the management of antimicrobial-resistant in cystic fibrosis patients.	Magizhvannan V, Veerappapillai S.	AMB Express	10.1186/s13568-025-01926-1	2025
	Structural analyses of the AAA+ ATPase domain of the transcriptional regulator GtrR in the BDSF quorum-sensing system in Burkholderia cenocepacia.	Yan XF, Yang C, Wang M, Yong Y, Deng Y, Gao YG.	FEBS Lett	10.1002/1873-3468.14244	2022
	Bronchoscopy and molecular diagnostic techniques to identify superimposed infections in COVID-19-associated ARDS: a case series from Ecuador during the second wave.	Briones Claudett KH, Briones-Claudett MH, Murillo Vasconez R, Benitez Solis JG, Briones Zamora KH, Freire AX, Barberan-Torres P, Grunauer M.	Front Med (Lausanne)	10.3389/fmed.2024.1409323	2024
	Impact of Blood Volume on Pathogen Detection and Time to Positivity in Paediatric Blood Cultures Using BACT/ALERT 3D Automated Systems.	Yadav NK, Raj N, Singh V, Saquib M, Yadav K, Agarwal D, Das A, Sen M, Agarwal J.	Cureus	10.7759/cureus.88454	2025
	Discovery of Homogentisic Acid as a Precursor in Trimethoprim Metabolism and Natural Product Biosynthesis.	McAvoy AC, Threatt PH, Kapcia J, Garg N.	ACS Chem Biol	10.1021/acschembio.2c00529	2023
	Formulation and efficacy testing of bio-organic fertilizer produced through solid-state fermentation of agro-waste by Burkholderia cenocepacia.	Bibi F, Ilyas N, Arshad M, Khalid A, Saeed M, Ansar S, Batley J.	Chemosphere	10.1016/j.chemosphere.2021.132762	2022
Genetics	Protocol to identify the signaling pathways of quorum sensing system in Burkholderia cenocepacia.	Song S, Cui B, Kong X, Deng Y.	STAR Protoc	10.1016/j.xpro.2024.103381	2024
	A Bacterial Mannose Binding Lectin as a Tool for the Enrichment of C- and O-Mannosylated Peptides.	Hutte HJ, Tiemann B, Shcherbakova A, Grote V, Hoffmann M, Povolo L, Lommel M, Strahl S, Vakhrushev SY, Rapp E, Buettner FFR, Halim A, Imberty A, Bakker H.	Anal Chem	10.1021/acs.analchem.2c00742	2022
	Characterization of glyphosate-resistant Burkholderia anthina and Burkholderia cenocepacia isolates from a commercial Roundup® solution.	Hertel R, Schone K, Mittelstadt C, Meissner J, Zschoche N, Collignon M, Kohler C, Friedrich I, Schneider D, Hoppert M, Kuhn R, Schwedt I, Scholz P, Poehlein A, Martienssen M, Ischebeck T, Daniel R, Commichau FM.	Environ Microbiol Rep	10.1111/1758-2229.13022	2022
	Identification of Burkholderia cepacia Complex: Comparing Conventional, Automated, and Molecular Methods in a Tertiary Care Center.	Periaiah P, Antony T, Samuel S.	Cureus	10.7759/cureus.70847	2024
	Glycomic profiling of parathyroid neoplasms via lectin microarray analysis.	Zheng Q, Cui M, Xiao J, Yang S, Chen T, Shi Y, Hu Y, Liao Q.	Endocrine	10.1007/s12020-024-04107-5	2025
Transcriptome	Discovery of Novel Thanatin-like Antimicrobial Peptides from Bean Bug Riptortus pedestris.	Panteleev PV, Teplovodskaya JS, Utkina AD, Smolina AA, Kruglikov RN, Safronova VN, Bolosov IA, Korobova OV, Borzilov AI, Ovchinnikova TV.	Pharmaceutics	10.3390/pharmaceutics16111453	2024
	Genomic analysis of Burkholderia cenocepacia isolated from a liver abscess in a patient with cystic fibrosis.	de Freitas Vianna E, Menezes NIM, de Almeida MM, de Freitas FAD, da Costa Ferreira Leite C, Firmida MC, de Medeiros DRI, Souza Leao R, Mattos Albano R, Andrade Marques E.	APMIS	10.1111/apm.13177	2021
	A survey of cystic fibrosis physicians' views on lung transplant referral in the era of elexacaftor/tezacaftor/ivacaftor.	Burdis N, Milinic T, Bartlett LE, Goss L, Tallarico E, Boyle A, Thaxton A, Turner GA, Benvenuto LJ, Faro A, Goss CH, Kapnadak SG, Ramos KJ.	Pediatr Pulmonol	10.1002/ppul.27273	2024
	ENaC contributes to macrophage dysfunction in cystic fibrosis.	Moran J, Pugh C, Brown N, Thomas A, Zhang S, McCauley E, Cephas A, Shrestha CL, Partida-Sanchez S, Bai S, Bruscia E, Kopp BT.	Am J Physiol Lung Cell Mol Physiol	10.1152/ajplung.00009.2025	2025
	Nebulized levofloxacin for chronic Burkholderia cenocepacia pulmonary infection in cystic fibrosis: A case report.	Dagenais RV, Quon BS, Franciosi AN.	Respir Med Case Rep	10.1016/j.rmcr.2022.101772	2022
	Fibrosis quística: patogenia bacteriana y moduladores del CFTR (regulador de conductancia transmembranal de la fibrosis quística).	Vargas-Roldan SY, Lezana-Fernandez JL, Cerna-Cortes JF, Partida-Sanchez S, Santos-Preciado JI, Rosales-Reyes R.	Bol Med Hosp Infant Mex	10.24875/bmhim.21000128	2022
	Acidic pH modulates Burkholderia cenocepacia antimicrobial susceptibility in the cystic fibrosis nutritional environment.	Morales LD, Av-Gay Y, Murphy MEP.	Microbiol Spectr	10.1128/spectrum.02731-23	2023
	Antimicrobial Agent Trimethoprim Influences Chemical Interactions in Cystic Fibrosis Pathogens via the ham Gene Cluster.	Jin J, Kulkarni AS, McAvoy AC, Garg N.	ACS Chem Biol	10.1021/acschembio.4c00562	2025
	''Clinical Management of Acute Mastoiditis in a Pediatric Patient with Leukocyte Adhesion Deficiency''.	Aghayev A, Gonul A, Basak H.	J Otol	10.26599/joto.2025.9540019	2025
	Complete Genome Sequence of Burkholderia cenocepacia Phage Paku.	Rezene S, Yao G, Le T, Burrowes B, Gonzalez C, Liu M, Gill J.	Microbiol Resour Announc	10.1128/mra.01220-21	2022
	Transcriptional Response of Burkholderia cenocepacia H111 to Severe Zinc Starvation.	Barnett JP.	Br J Biomed Sci	10.3389/bjbs.2023.11597	2023
	A prospective evaluation of hidden bacterial involvement and antibiotic efficacy in nonbacterial CP/CPPS: addressing an underexplored therapeutic approach.	Kitano H, Ohge H, Tadera K, Kohada Y, Hatayama T, Shikuma H, Tasaka R, Takemoto K, Miyamoto S, Kobatake K, Sekino Y, Kitagawa H, Kashiyama S, Hinata N.	World J Urol	10.1007/s00345-025-05936-3	2025
Pathogenicity	Case report: Cervical suppurative lymphadenitis caused by burkholderia multivorans in a healthy child.	Niu BB, Xu JJ, Li JA, Zhu LD.	BMC Infect Dis	10.1186/s12879-025-11033-y	2025
Genetics	Targeted A-to-G base editing in human mitochondrial DNA with programmable deaminases.	Cho SI, Lee S, Mok YG, Lim K, Lee J, Lee JM, Chung E, Kim JS.	Cell	10.1016/j.cell.2022.03.039	2022
Pathogenicity	Burkholderia cenocepacia BCAM2418-induced antibody inhibits bacterial adhesion, confers protection to infection and enables identification of host glycans as adhesin targets.	Pimenta AI, Kilcoyne M, Bernardes N, Mil-Homens D, Joshi L, Fialho AM.	Cell Microbiol	10.1111/cmi.13340	2021
	A Burkholderia cenocepacia-like environmental isolate strongly inhibits the plant fungal pathogen Zymoseptoria tritici.	Song T, Gupta S, Sorokin Y, Frenkel O, Cytryn E, Friedman J.	Appl Environ Microbiol	10.1128/aem.02222-23	2024
	A Polyclonal Antibody against a Burkholderia cenocepacia OmpA-like Protein Strongly Impairs Pseudomonas aeruginosa and B. multivorans Virulence.	Seixas AMM, Gomes SC, Silva C, Moreira LM, Leitao JH, Sousa SA.	Vaccines (Basel)	10.3390/vaccines12020207	2024
	Proteomics insights into the Burkholderia cenocepacia phosphorus stress response.	Shropshire H, Jones RA, Aguilo-Ferretjans MM, Scanlan DJ, Chen Y.	Environ Microbiol	10.1111/1462-2920.15451	2021
	Glycoproteomic and proteomic analysis of Burkholderia cenocepacia reveals glycosylation events within FliF and MotB are dispensable for motility.	Lewis JM, Jebeli L, Coulon PML, Lay CE, Scott NE.	Microbiol Spectr	10.1128/spectrum.00346-24	2024
Metabolism	Detection of cytosine methylation in Burkholderia cenocepacia by single-molecule real-time sequencing and whole-genome bisulfite sequencing.	Vandenbussche I, Sass A, Van Nieuwerburgh F, Pinto-Carbo M, Mannweiler O, Eberl L, Coenye T.	Microbiology (Reading)	10.1099/mic.0.001027	2021
	Essential Genes Discovery in Microorganisms by Transposon-Directed Sequencing (Tn-Seq): Experimental Approaches, Major Goals, and Future Perspectives.	Fernandez-Garcia G, Valdes-Chiara P, Villazan-Gamonal P, Alonso-Fernandez S, Manteca A.	Int J Mol Sci	10.3390/ijms252011298	2024
	Effect of Ultraviolet-c (UVc) light and ozone on the survival of Mycobacterium abscessus complex organisms associated with cystic fibrosis.	Moore JE, Millar BC.	Int J Mycobacteriol	10.4103/ijmy.ijmy_87_22	2022
	The Changing Transplant Landscape in the Era of Elexacaftor/Tezacaftor/Ivacaftor: A Word of Caution.	Semenchuk J, Tuff-Gordon E, Ma X, Sykes J, Cheng SY, Aversa M, Chaparro C, Tullis E, Stephenson AL.	Clin Transplant	10.1111/ctr.70317	2025
	RNA-Seq reveals that Pseudomonas aeruginosa mounts growth medium-dependent competitive responses when sensing diffusible cues from Burkholderia cenocepacia.	Leinweber A, Laffont C, Lardi M, Eberl L, Pessi G, Kummerli R.	Commun Biol	10.1038/s42003-024-06618-3	2024
	Epidemiology and Clinical Features of Burkholderia Bacteremia at a Hospital in India.	Kar M, Tejan N, Jamwal A, Dubey A, Singh R, Sahu C, Patel SS, Kumari P, Ghar M.	Am J Trop Med Hyg	10.4269/ajtmh.23-0390	2024
	Persistent Pneumonia in an Infant.	Sekar A, Gupta A, Rawat A, Rudramurthy SM, Kumar R, Bhatia A.	Indian Pediatr		2021
Pathogenicity	Disruption of biofilms and killing of Burkholderia cenocepacia from cystic fibrosis lung using an antioxidant-antibiotic combination therapy.	Aiyer A, Manoharan A, Paino D, Farrell J, Whiteley GS, Kriel FH, Glasbey TO, Manos J, Das T.	Int J Antimicrob Agents	10.1016/j.ijantimicag.2021.106372	2021
	Genome-based taxonomy of Burkholderia sensu lato: Distinguishing closely related species.	Bach E, Volpiano CG, Sant'Anna FH, Passaglia LMP.	Genet Mol Biol	10.1590/1678-4685-gmb-2023-0122	2023
	Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation.	Quintana-Feliciano R, Kottur J, Ni M, Ghosh R, Salas-Estrada L, Ahlsen G, Rechkoblit O, Shapiro L, Filizola M, Fang G, Aggarwal AK.	Nat Commun	10.1038/s41467-024-52130-x	2024
	Infections Management in the Lung Transplant Setting in Italy: A Web-Survey.	Lombardi A, Grossi P, Mikulska M, Giannella M, Pascale R, Marinello S, Montagnani F, Seminari E, Corcione S, Bandera A, Bertani A, Mularoni A, Infection Prevention and Treatment Working Group of the LUNG-SITO study group.	Transpl Infect Dis	10.1111/tid.14413	2025
Enzymology	Enhancement of the Thermostability of Microbacterium Esterase by Combinatorial Rational Design.	Peng W, Wu X, Ma B, Xu Y.	Molecules	10.3390/molecules29245839	2024
	PEG-PLGA nanoparticles deposited in Pseudomonas aeruginosa and Burk h olderia cenocepacia.	Tchatchiashvili T, Duering H, Mueller-Boetticher L, Grune C, Fischer D, Pletz MW, Makarewicz O.	J Pharm Anal	10.1016/j.jpha.2024.01.007	2024
	Seasonal Changes and Age-Related Effects on the Intestinal Microbiota of Captive Chinese Monals (Lophophorus lhuysii).	Huang L, Zheng Y, Feng S, Wu B, Chen L, Xu X, Wang B, Li W, Zhou C, Zhang L.	Animals (Basel)	10.3390/ani14233418	2024
Pathogenicity	Functional interplay between non-canonical inflammasomes and autophagy in inflammatory responses and diseases.	Yi YS.	Korean J Physiol Pharmacol	10.4196/kjpp.24.240	2025
Genetics	Genomic features, antimicrobial susceptibility, and epidemiological insights into Burkholderia cenocepacia clonal complex 31 isolates from bloodstream infections in India.	Saroha T, Patil PP, Rana R, Kumar R, Kumar S, Singhal L, Gautam V, Patil PB.	Front Cell Infect Microbiol	10.3389/fcimb.2023.1151594	2023
	Surface-Exposed Protein Moieties of Burkholderia cenocepacia J2315 in Microaerophilic and Aerobic Conditions.	Seixas AMM, Silva C, Marques JMM, Mateus P, Rodriguez-Ortega MJ, Feliciano JR, Leitao JH, Sousa SA.	Vaccines (Basel)	10.3390/vaccines12040398	2024
	Isolation and identification of metallotolerant bacteria with a potential biotechnological application.	Parades-Aguilar J, Calderon K, Agustin-Salazar S, Cerruti P, Ambrogi V, Gamez-Meza N, Medina-Juarez LA.	Sci Rep	10.1038/s41598-024-54090-0	2024
Metabolism	Phenotypic characterization of trimeric autotransporter adhesin-defective bcaC mutant of Burkholderia cenocepacia: cross-talk towards the histidine kinase BCAM0218.	Pimenta AI, Mil-Homens D, Pinto SN, Fialho AM.	Microbes Infect	10.1016/j.micinf.2020.05.018	2020
	Carbapenem-Resistant Burkholderia cepacia Complex Isolates Carrying bla _NDM-1 and bla _NDM-5 in Ventilator-Associated Pneumonia Patients and Contaminated Ventilator Tubing.	Saeed M, Rasheed F, Rasool MH, Hayat S, Khurshid M.	Transbound Emerg Dis	10.1155/2024/3352135	2024
	Eradication of Burkholderia cepacia complex in cystic fibrosis patients with inhalation of amiloride and tobramycin combined with oral cotrimoxazole.	Akkerman-Nijland AM, Rottier BL, Holstein J, Winter RLJ, Touw DJ, Akkerman OW, Koppelman GH.	ERJ Open Res	10.1183/23120541.00055-2023	2023
	A new selective culture medium for isolation of Burkholderia cepacia complex in pharmaceutical industry.	Yu M, Wang S, Zhong Y, Yuan L, An L, Feng D, Liu Z, Ma S.	Front Microbiol	10.3389/fmicb.2025.1631983	2025
	Investigation of arsenic-resistant, arsenite-oxidizing bacteria for plant growth promoting traits isolated from arsenic contaminated soils.	Laha A, Bhattacharyya S, Sengupta S, Bhattacharyya K, GuhaRoy S.	Arch Microbiol	10.1007/s00203-021-02460-x	2021
Pathogenicity	Vaccines to Overcome Antibiotic Resistance: The Challenge of Burkholderia cenocepacia.	Scoffone VC, Barbieri G, Buroni S, Scarselli M, Pizza M, Rappuoli R, Riccardi G.	Trends Microbiol	10.1016/j.tim.2019.12.005	2020
	Biodegradation of dioxins by Burkholderia cenocepacia strain 869T2: Role of 2-haloacid dehalogenase.	Nguyen BT, Hsieh JL, Lo SC, Wang SY, Hung CH, Huang E, Hung SH, Chin WC, Huang CC.	J Hazard Mater	10.1016/j.jhazmat.2020.123347	2021
	Comparative analysis of different methods used for molecular characterization of Burkholderia cepacia complex isolated from noncystic fibrosis conditions.	Modapathi SR, Rohit A, Aditya V, Shetty VP, Kotian A, Mohanapriya, Rai P, Karunasagar I, Deekshit VK.	Indian J Med Microbiol	10.1016/j.ijmmb.2021.09.012	2022
	Is Increased Biofilm Formation Associated with Decreased Antimicrobial Susceptibility? A Systematic Literature Review.	Madduri A, Vanommeslaeghe L, Coenye T.	Microorganisms	10.3390/microorganisms13102292	2025
	Multi-year comparison of VITEK MS performance for identification of rarely encountered pathogenic Gram-negative organisms (GNOs) in a large integrated Canadian healthcare region.	Church DL, Griener T, Gregson D.	Microbiol Spectr	10.1128/spectrum.02276-24	2024
	In-Silico Analysis Highlights the Existence in Members of Burkholderia cepacia Complex of a New Class of Adhesins Possessing Collagen-like Domains.	Estevens R, Mil-Homens D, Fialho AM.	Microorganisms	10.3390/microorganisms11051118	2023
	Interactions between Pseudomonas aeruginosa and six opportunistic pathogens cover a broad spectrum from mutualism to antagonism.	Laffont C, Wechsler T, Kummerli R.	Environ Microbiol Rep	10.1111/1758-2229.70015	2024
Metabolism	The BPtpA protein from Burkholderia cenocepacia belongs to a new subclass of low molecular weight protein tyrosine phosphatases.	Sanchez-Rodriguez R, Gonzalez GM, Becerril-Garcia MA, Trevino-Rangel RJ, Marcos-Vilchis A, Gonzalez-Pedrajo B, Valvano MA, Andrade A.	Arch Biochem Biophys	10.1016/j.abb.2020.108277	2020
	Mutations in ampD cause hyperproduction of AmpC and CmcB beta-lactamases and high resistance to beta-lactam antibiotics in Chromobacterium violaceum.	Laranjeiro LG, Neme CEM, Previato-Mello M, Batista BB, Henriques I, da Silva Neto JF.	Microbiol Spectr	10.1128/spectrum.00916-25	2025
Enzymology	Burkholderia cenocepacia ET12 transmission in adults with cystic fibrosis.	Blanchard AC, Tang L, Tadros M, Muller M, Spilker T, Waters VJ, LiPuma JJ, Tullis E.	Thorax	10.1136/thoraxjnl-2019-214098	2020
	Phage-antibiotic synergy reduces Burkholderia cenocepacia population.	Mankovich AG, Maciel K, Kavanaugh M, Kistler E, Muckle E, Weingart CL.	BMC Microbiol	10.1186/s12866-022-02738-0	2023
	Complete Genome Sequence of Burkholderia cenocepacia Phage Mica.	Garcia J, Yao G, Vizoso-Pinto MG, Clark J, Le T, Gonzalez C, Gill J, Liu M.	Microbiol Resour Announc	10.1128/mra.01407-20	2021
	Burkholderia cenocepacia keratitis.	Behera G, Sugumar R, Sistla S, Stephen M, Kaliaperumal S, Babu KR.	Indian J Ophthalmol	10.4103/ijo.ijo_1905_20	2020
Enzymology	Identification of a system for hydroxamate xenosiderophore-mediated iron transport in Burkholderia cenocepacia.	Hussein SM, Sofoluwe A, Paleja A, Duhme-Klair A, Thomas MS.	Microbiology (Reading)	10.1099/mic.0.001425	2024
	Complete Genome Sequence of Burkholderia cenocepacia Phage Magia.	Gafford-Gaby D, Yao G, Le T, Clark J, Gonzalez C, Gill J, Liu M.	Microbiol Resour Announc	10.1128/mra.01473-20	2021
	A type VI secretion system in Burkholderia species cenocepacia and orbicola triggers distinct macrophage death pathways independent of the pyrin inflammasome.	Loeven NA, Dabi C, Pennington JP, Reuven AD, McGee AP, Mwaura BW, Bliska JB.	Infect Immun	10.1128/iai.00316-24	2024
	Calcium sulfate matrix as local antibiotic carrier in the mastoid.	Dalbert A, Bachinger D, Soyka M, Roosli C, Inci I, Schuurmans MM, Achermann Y, Huber A.	Clin Case Rep	10.1002/ccr3.5516	2022
	Galactosylated liposomes for targeted encapsulation and enhanced cytotoxicity of Mistletoe Lectin, an antitumoral type 2 ribosome-inactivating protein.	Kaufmann J, Cetin E, Kraus T, Rieger H, Leneweit G.	Int J Pharm X	10.1016/j.ijpx.2025.100392	2025
Phylogeny	Isolation and characterization of Burkholderia cenocepacia CR318, a phosphate solubilizing bacterium promoting corn growth.	You M, Fang S, MacDonald J, Xu J, Yuan ZC.	Microbiol Res	10.1016/j.micres.2019.126395	2020
	Isolation and screening of potassium solubilizing bacteria from saxicolous habitat and their impact on tomato growth in different soil types.	Raji M, Thangavelu M.	Arch Microbiol	10.1007/s00203-021-02284-9	2021
	Rationally designed pooled CRISPRi-seq uncovers an inhibitor of bacterial peptidyl-tRNA hydrolase.	Rahman ASMZ, Syroegin EA, Novomisky Nechcoff J, Devarajan A, Polikanov YS, Cardona ST.	Cell Rep	10.1016/j.celrep.2024.114967	2024
Cultivation	Application of Dimethicone to Prevent Culture Media from Drying in Microbiological Diagnostics.	Savinova TA, Bocharova YA, Mayansky NA, Chebotar IV.	Sovrem Tekhnologii Med	10.17691/stm2023.15.1.02	2023
	Bacteriophage steering of Burkholderia cenocepacia toward reduced virulence and increased antibiotic sensitivity.	Ruest MK, Supina BSI, Dennis JJ.	J Bacteriol	10.1128/jb.00196-23	2023
Enzymology	A case report of successful eradication of new isolates of Burkholderia cenocepacia in a child with cystic fibrosis.	Sputael V, Van Schandevyl G, Hanssens L.	Acta Clin Belg	10.1080/17843286.2019.1630585	2020
	Carnosol attenuates Acinetobacter baumannii virulence by interfering with indole-mediated quorum sensing.	Cui B, Peng G, Wang M, Kong X, Wei H, Ling X, Wu G, Deng Y.	Virulence	10.1080/21505594.2025.2530169	2025
	BBSdb, an open resource for bacterial biofilm-associated proteins.	Zhang Z, Pan Y, Hussain W, Chen G, Li E.	Front Cell Infect Microbiol	10.3389/fcimb.2024.1428784	2024
Metabolism	Small RNA NcS27 co-regulates utilization of carbon sources in Burkholderia cenocepacia J2315.	Sass AM, De Waele S, Daled S, Devreese B, Deforce D, Van Nieuwerburgh F, Coenye T.	Microbiology (Reading)	10.1099/mic.0.000848	2019
	Incidence, Compliance, and Risk Factor Associated with Central Line-Associated Bloodstream Infection (CLABSI) in Intensive Care Unit (ICU) Patients: A Multicenter Study in an Upper Middle-Income Country.	Rajandra A, Yunos NM, Teo CH, Kukreja A, Suhaimi NA, Mohd Razali SZ, Basri S, Teh CSJ, Leong CL, Ismail I, Azmel A, Yunus NHM, Rajahram GS, Ismail AJ, Deva SR, Kee PW, Trgs Working Group, Ponnampalavanar SSS.	Antibiotics (Basel)	10.3390/antibiotics14030271	2025
	The Impact of Antimicrobial Resistance in Cystic Fibrosis.	Vitiello A, Blasi F, Sabbatucci M, Zovi A, Miele F, Ponzo A, Langella R, Boccellino M.	J Clin Med	10.3390/jcm13061711	2024
Enzymology	Expression and Purification of a Human Pluripotent Stem Cell-Specific Lectin Probe, rBC2LCN.	Tateno H.	Methods Mol Biol	10.1007/978-1-0716-0430-4_44	2020
	Nanoparticles of Cs_0.33WO₃ as Antibiofilm Agents and Photothermal Treatment to Inhibit Biofilm Formation.	Wong MY, Lin BS, Hu PS, Huang TY, Huang YK.	ACS Omega	10.1021/acsomega.4c01212	2024
	PEGylated mucus-penetrating nanocrystals for lung delivery of a new FtsZ inhibitor against Burkholderia cenocepacia infection.	Costabile G, Provenzano R, Azzalin A, Scoffone VC, Chiarelli LR, Rondelli V, Grillo I, Zinn T, Lepioshkin A, Savina S, Miro A, Quaglia F, Makarov V, Coenye T, Brocca P, Riccardi G, Buroni S, Ungaro F.	Nanomedicine	10.1016/j.nano.2019.102113	2020
Pathogenicity	Staphylococcus aureus products subvert the Burkholderia cenocepacia-induced inflammatory response in airway epithelial cells.	Ji Y, Bolhuis A, Watson ML.	J Med Microbiol	10.1099/jmm.0.001100	2019
Metabolism	Structural and Functional Characterization of Dynamic Oligomerization in Burkholderia cenocepacia HMG-CoA Reductase.	Peacock RB, Hicks CW, Walker AM, Dewing SM, Lewis KM, Abboud JC, Stewart SWA, Kang C, Watson JM.	Biochemistry	10.1021/acs.biochem.9b00494	2019
Enzymology	First cases of Burkholderia cenocepacia IIIA neonatal sepsis in Central African Republic.	Frank T, Gil-Cuesta J, Mbecko JR, Sanke H, Lakis C, Fleche-Mateos AL, Berlioz-Arthaud A.	Pan Afr Med J	10.11604/pamj.2020.36.330.24512	2020
	Quorum sensing and DNA methylation play active roles in clinical Burkholderia phase variation.	Coulon PML, Groleau M-C, Hachani A, Padula MP, Stinear TP, Deziel E.	J Bacteriol	10.1128/jb.00531-24	2025
	Isolation and characterization of rhizobacteria from lentil for arsenic resistance and plant growth promotion.	Laha A, Sengupta S, Bhattacharyya S, Bhattacharyya K, GuhaRoy S.	3 Biotech	10.1007/s13205-023-03873-9	2024
	Surface Motility Favors Codependent Interaction between Pseudomonas aeruginosa and Burkholderia cenocepacia.	Morin C, Landry M, Groleau MC, Deziel E.	mSphere	10.1128/msphere.00153-22	2022
	Cell envelope structural and functional contributions to antibiotic resistance in Burkholderia cenocepacia.	Hogan AM, Motnenko A, Rahman ASMZ, Cardona ST.	J Bacteriol	10.1128/jb.00441-23	2024
	Cefiderocol to manage chronic, multi-drug-resistant Burkholderia cepacia complex infection in a patient with cystic fibrosis: a case report.	Nye C, Duckers J, Dhillon R.	Access Microbiol	10.1099/acmi.0.000413	2022
	Discovery of inhibition of Burkholderia cenocepacia, Pseudomonas aeruginosa and Stenotrophomonas maltophilia by the Brown Rot Basidiomycete Fungus, Postia placenta.	McIlroy R, Nelson DW, Millar BC, Murphy A, Rao JR, Downey DG, Moore JE.	Ulster Med J		2021
Enzymology	L-Rhamnose Dehydrogenase LraA of Aspergillus niger Shows High Substrate Specificity Matching Its Expression Profile.	Terebieniec A, Xu L, Peng M, Makela MR, Vries RP.	J Fungi (Basel)	10.3390/jof11040301	2025
Pathogenicity	Inhibition of Rhizoctonia solani RhCh-14 and Pythium ultimum PyFr-14 by Paenibacillus polymyxa NMA1017 and Burkholderia cenocepacia CACua-24: A proposal for biocontrol of phytopathogenic fungi.	Chavez-Ramirez B, Kerber-Diaz JC, Acoltzi-Conde MC, Ibarra JA, Vasquez-Murrieta MS, Estrada-de Los Santos P.	Microbiol Res	10.1016/j.micres.2019.126347	2020
	The Bep gene cluster in Burkholderia cenocepacia H111 codes for a water-insoluble exopolysaccharide essential for biofilm formation.	Bellich B, Teran LC, Fazli MM, Berti F, Rizzo R, Tolker-Nielsen T, Cescutti P.	Carbohydr Polym	10.1016/j.carbpol.2022.120318	2023
Metabolism	Physiological, biochemical and proteomic insight into integrated strategies of an endophytic bacterium Burkholderia cenocepacia strain YG-3 response to cadmium stress.	Wang X, Zhang X, Liu X, Huang Z, Niu S, Xu T, Zeng J, Li H, Wang T, Gao Y, Huang M, Cao L, Zhu Y.	Metallomics	10.1039/c9mt00054b	2019
	Epidemiology of Burkholderia Infections in People with Cystic Fibrosis in Canada between 2000 and 2017.	Zlosnik JEA, Henry DA, Hird TJ, Hickman R, Campbell M, Cabrera A, Laino Chiavegatti G, Chilvers MA, Sadarangani M.	Ann Am Thorac Soc	10.1513/annalsats.201906-443oc	2020
Proteome	What Are We Missing by Using Hydrophilic Enrichment? Improving Bacterial Glycoproteome Coverage Using Total Proteome and FAIMS Analyses.	Ahmad Izaham AR, Ang CS, Nie S, Bird LE, Williamson NA, Scott NE.	J Proteome Res	10.1021/acs.jproteome.0c00565	2021
Enzymology	Improving Cofactor Promiscuity of HMG-CoA Reductase from Ruegeria pomeroyi Through Rational Design.	Xue H, Huang Y, Shah AM, Wang X, Hu Y, Zhang L, Zhao ZK.	Biomolecules	10.3390/biom15070976	2025
	The mechanism of action of auranofin analogs in B. cenocepacia revealed by chemogenomic profiling.	Maydaniuk DT, Martens B, Iqbal S, Hogan AM, Lorente Cobo N, Motnenko A, Truong D, Liyanage SH, Yan M, Prehna G, Cardona ST.	Microbiol Spectr	10.1128/spectrum.03201-23	2024
	Protozoan predation enhances stress resistance and antibiotic tolerance in Burkholderia cenocepacia by triggering the SOS response.	Moron A, Tarhouchi AE, Belinchon I, Valenzuela JM, de Francisco P, Martin-Gonzalez A, Amaro F.	ISME J	10.1093/ismejo/wrae014	2024
Metabolism	The Eno Gene of Burkholderia cenocepacia Strain 71-2 is Involved in Phosphate Solubilization.	Liu C, Mou L, Yi J, Wang J, Liu A, Yu J.	Curr Microbiol	10.1007/s00284-019-01642-7	2019
	Engineering Saccharomyces cerevisiae for growth on xylose using an oxidative pathway.	Tanaka K, Yukawa T, Bamba T, Wakiya M, Kumokita R, Jin YS, Kondo A, Hasunuma T.	Appl Microbiol Biotechnol	10.1007/s00253-025-13417-1	2025
	Membrane-enclosed Pseudomonas quinolone signal attenuates bacterial virulence by interfering with quorum sensing.	Li X, Wang G, Guo Q, Cui B, Wang M, Song S, Yang L, Deng Y.	Appl Environ Microbiol	10.1128/aem.01184-23	2023
	A Preliminary Study on Microbiota Characteristics of Bronchoalveolar Lavage Fluid in Patients with Pulmonary Nodules Based on Metagenomic Next-Generation Sequencing.	Yuan Q, Wang X, Li Z, Guo W, Cheng H, Cao Q.	Biomedicines	10.3390/biomedicines11020631	2023
	Which pathogens should we worry about?	Jones AM.	Paediatr Respir Rev	10.1016/j.prrv.2019.02.007	2019
Genetics	Metagenome-based diversity and functional analysis of culturable microbes in sugarcane.	Lin H, Wu L, Zhang L, Ta QK, Liu P, Song J, Yang X.	Microbiol Spectr	10.1128/spectrum.01982-24	2025
	Burkholderia Cepacia Complex in Personal Care Products: Molecular Epidemiology and Susceptibility to Preservatives.	Wen X, Xie X, Zhang S, Sun T, Liu J, Li W.	J Cosmet Sci		2020
	Aberrant Glycosylation in Pancreatic Ductal Adenocarcinoma 3D Organoids Is Mediated by KRAS Mutations.	Nakahashi H, Oda T, Shimomura O, Akashi Y, Takahashi K, Miyazaki Y, Furuta T, Kuroda Y, Louphrasitthiphol P, Mathis BJ, Tateno H.	J Oncol	10.1155/2024/1529449	2024
Metabolism	Chemo-Mechanical Coupling in the Transport Cycle of a Heme ABC Transporter.	Tamura K, Sugimoto H, Shiro Y, Sugita Y.	J Phys Chem B	10.1021/acs.jpcb.9b04356	2019
Genetics	Clinical value of metagenomic next-generation sequencing in screening oropharyngeal colonization in patients undergoing allogeneic hematopoietic stem cell transplantation: a prospective observational study.	Zhang Y, Ge J, Wang Y, Tang Z, Ma X, Liu J, Wu D, Wu X.	Microbiol Spectr	10.1128/spectrum.00028-25	2025
	Identification of CLEC10A as a human lectin for pancreatic ductal adenocarcinoma.	Tsukamoto S, Tateno H, Shimomura O, Yamamoto K, Saito S, Murakami J, Nakahashi H, Miyazaki Y, Enomoto T, Oda T.	Sci Rep	10.1038/s41598-025-02404-1	2025
Metabolism	Draft Genome of Burkholderia cenocepacia TAtl-371, a Strain from the Burkholderia cepacia Complex Retains Antagonism in Different Carbon and Nitrogen Sources.	Rojas-Rojas FU, Sanchez-Lopez D, Tapia-Garcia EY, Arroyo-Herrera I, Maymon M, Humm E, Huntemann M, Clum A, Pillay M, Palaniappan K, Varghese N, Mikhailova N, Stamatis D, Reddy TBK, Ivanova N, Kyrpides N, Woyke T, Shapiro N, Hirsch AM, Ibarra JA, Estrada-de Los Santos P.	Curr Microbiol	10.1007/s00284-019-01657-0	2019
	Hemophagocytic Lymphohistiocytosis in Children with Chronic Granulomatous Disease-Single-Center Experience from North India.	Vignesh P, Loganathan SK, Sudhakar M, Chaudhary H, Rawat A, Sharma M, Shekar A, Vaiphei K, Kumar N, Singh Sachdeva MU, Jindal AK, Suri D, Gupta A, Ray P, Imai K, Ohara O, Nonoyama S, Lau YL, Singh S.	J Allergy Clin Immunol Pract	10.1016/j.jaip.2020.11.041	2021
	Development and evaluation of a real-time multienzyme isothermal rapid amplification assay for rapid detection of Streptococcus pneumoniae.	Xing Y, Duan Z, Jiang Y, Li M, Lu W, Li J.	Sci Rep	10.1038/s41598-024-68524-2	2024
Genetics	Double-stranded DNA deaminase DddA^E1347A can increase the efficiency and targeting range of cytidine base editors.	Qian Y, Hui F, Niu W, Wang D, Hao Y, Meng Q, Ren S, Kong D, Gong H, Wu J, Chen K, Alariqi M, Gao J, Li Z, Jin S.	Genome Biol	10.1186/s13059-025-03849-3	2025
	Bacterial Subversion of Autophagy in Cystic Fibrosis.	Flores-Vega VR, Vargas-Roldan SY, Lezana-Fernandez JL, Lascurain R, Santos-Preciado JI, Rosales-Reyes R.	Front Cell Infect Microbiol	10.3389/fcimb.2021.760922	2021
Phylogeny	16S rRNA amplicon sequencing and antimicrobial resistance profile of intensive care units environment in 41 Brazilian hospitals.	de Bastiani DC, Silva CV, Christoff AP, Cruz GNF, Tavares LD, de Araujo LSR, Tomazini BM, Arns B, Piastrelli FT, Cavalcanti AB, de Oliveira LFV, Pereira AJ.	Front Public Health	10.3389/fpubh.2024.1378413	2024
	Study on the Influence of UV Light on Selective Antibacterial Activity of Silver Nanoparticle Synthesized Utilizing Protein/Polypeptide-Rich Aqueous Extract from The Common Walkingstick, Diapheromera femorata.	Cho JL, Allain LG, Yoshida S.	Materials (Basel)	10.3390/ma17030713	2024
	Conformational Dynamics of the Active Site Loop in Dihydroorotase Highlighting the Limitations of Loop-In Structures for Inhibitor Docking.	Huang YH, Huang TY, Wang MC, Huang CY.	Int J Mol Sci	10.3390/ijms26199688	2025
Genetics	Revealing the Metabolic Alterations during Biofilm Development of Burkholderia cenocepacia Based on Genome-Scale Metabolic Modeling.	Altay O, Zhang C, Turkez H, Nielsen J, Uhlen M, Mardinoglu A.	Metabolites	10.3390/metabo11040221	2021
Genetics	Insights into the genome diversity and virulence of two clinical isolates of Burkholderia cenocepacia.	Salloum T, Nassour E, Araj GF, Abboud E, Tokajian S.	J Med Microbiol	10.1099/jmm.0.000759	2018
	Burkholderia cepacia complex: 11 years of surveillance in patients with Cystic Fibrosis in Posadas, Argentina.	Martina PF, Martinez M, Rivas S, Leguizamon L, Von Specht M, Ferreras J.	Rev Argent Microbiol	10.1016/j.ram.2019.08.002	2020
	Deep crypt secretory cells shape region-specific mucin glycosylation patterns in the mouse colon.	Sugahara D, Kawakami H, Akimoto Y.	PLoS One	10.1371/journal.pone.0326157	2025
	Burkholderia cepacia complex in cystic fibrosis: critical gaps in diagnosis and therapy.	Gutierrez Santana JC, Coria Jimenez VR.	Ann Med	10.1080/07853890.2024.2307503	2024
Phylogeny	Fourier Transform Infrared Spectroscopy for Typing Burkholderia cenocepacia ET12 Isolates.	Barker KR, Santino M, LiPuma JJ, Tullis E, Muller MP, Matukas LM, Tadros M.	Microbiol Spectr	10.1128/spectrum.01831-21	2021
	Acanthamoeba Mannose and Laminin Binding Proteins Variation across Species and Genotypes.	Corsaro D.	Microorganisms	10.3390/microorganisms10112162	2022
	A flagella-dependent Burkholderia jumbo phage controls rice seedling rot and steers Burkholderia glumae toward reduced virulence in rice seedlings.	Supina BSI, McCutcheon JG, Peskett SR, Stothard P, Dennis JJ.	mBio	10.1128/mbio.02814-24	2025
Metabolism	Identification of AHL- and BDSF-Controlled Proteins in Burkholderia cenocepacia by Proteomics.	Liu Y, Pessi G, Riedel K, Eberl L.	Methods Mol Biol	10.1007/978-1-4939-7309-5_15	2018
Genetics	Genomic editing in Burkholderia multivorans by CRISPR/Cas9.	Ferreira MR, Queiroga V, Moreira LM.	Appl Environ Microbiol	10.1128/aem.02250-23	2024
	Oridonin Attenuates Burkholderia cenocepacia Virulence by Suppressing Quorum-Sensing Signaling.	Li X, Wang K, Wang G, Cui B, Song S, Sun X, Deng Y.	Microbiol Spectr	10.1128/spectrum.01787-22	2022
	Pellicle Biofilm Formation in Burkholderia cenocepacia J2315 is Epigenetically Regulated through WspH, a Hybrid Two-Component System Kinase-Response Regulator.	Sass A, Vandenbussche I, Bellich B, Cescutti P, Coenye T.	J Bacteriol	10.1128/jb.00017-22	2022
	Metagenomic next-generation sequencing performed on blood samples for the early recognition of severe Pneumocystis pneumonia in critical hematological patients.	Shen XD, Pan XD, Shi SS, Xu T, Xue SL, Wang J, Wan CL, Yao YT, Lei W, Tao T.	Medicine (Baltimore)	10.1097/md.0000000000033399	2023
	Bacterial Adaptation in Structured Environments: Lessons from Darwin's Finches.	Harrison JJ, Parsek MR, Tseng BS.	Trends Microbiol	10.1016/j.tim.2020.10.010	2021
	The Engineered Lysin CF-370 Is Active Against Antibiotic-Resistant Gram-Negative Pathogens In Vitro and Synergizes With Meropenem in Experimental Pseudomonas aeruginosa Pneumonia.	Sauve K, Watson A, Oh JT, Swift S, Vila-Farres X, Abdelhady W, Xiong YQ, LeHoux D, Woodnutt G, Bayer AS, Schuch R.	J Infect Dis	10.1093/infdis/jiae027	2024
Metabolism	A Catalyst from Burkholderia cenocepacia for Efficient Anti-Prelog's Bioreduction of 3,5-Bis(Trifluoromethyl) Acetophenone.	Yu S, Li H, Lu Y, Zheng G.	Appl Biochem Biotechnol	10.1007/s12010-017-2628-8	2018
	Targeting a Multidrug-Resistant Pathogen: First Generation Antagonists of Burkholderia cenocepacia's BC2L-C Lectin.	Bermeo R, Lal K, Ruggeri D, Lanaro D, Mazzotta S, Vasile F, Imberty A, Belvisi L, Varrot A, Bernardi A.	ACS Chem Biol	10.1021/acschembio.2c00532	2022
	A universal stress protein upregulated by hypoxia has a role in Burkholderia cenocepacia intramacrophage survival: Implications for chronic infection in cystic fibrosis.	O'Connor A, Jurado-Martin I, Mysior MM, Manzira AL, Drabinska J, Simpson JC, Lucey M, Schaffer K, Berisio R, McClean S.	Microbiologyopen	10.1002/mbo3.1311	2023
	Specific inactivation of an antifungal bacterial siderophore by a fungal plant pathogen.	Ho YN, Hoo SY, Wang BW, Hsieh CT, Lin CC, Sun CH, Peng CC, Lin C, Yang YL.	ISME J	10.1038/s41396-020-00871-0	2021
Metabolism	A novel two-component system modulates quorum sensing and pathogenicity in Burkholderia cenocepacia.	Cui C, Yang C, Song S, Fu S, Sun X, Yang L, He F, Zhang LH, Zhang Y, Deng Y.	Mol Microbiol	10.1111/mmi.13915	2018
	GSAMDA: a computational model for predicting potential microbe-drug associations based on graph attention network and sparse autoencoder.	Tan Y, Zou J, Kuang L, Wang X, Zeng B, Zhang Z, Wang L.	BMC Bioinformatics	10.1186/s12859-022-05053-7	2022
	Transcriptome-guided engineering of a native niacin transporter in Lactiplantibacillus plantarum unveils metabolic rewiring for NMN biosynthesis.	Kong L, Li X, He Q, Yao Q, Ai L, Qin J.	Front Microbiol	10.3389/fmicb.2025.1637666	2025
	Evaluation of three sample preparation methods for the identification of clinical strains by using two MALDI-TOF MS systems.	Wang J, Wang H, Cai K, Yu P, Liu Y, Zhao G, Chen R, Xu R, Yu M.	J Mass Spectrom	10.1002/jms.4696	2021
Pathogenicity	Broad-spectrum antimicrobial activity by Burkholderia cenocepacia TAtl-371, a strain isolated from the tomato rhizosphere.	Rojas-Rojas FU, Salazar-Gomez A, Vargas-Diaz ME, Vasquez-Murrieta MS, Hirsch AM, De Mot R, Ghequire MGK, Ibarra JA, Estrada-de Los Santos P.	Microbiology (Reading)	10.1099/mic.0.000675	2018
	Microscopy and modelling investigations on the morphology of the biofilm exopolysaccharide produced by Burkholderia multivorans strain C1576.	Cacioppo M, De Zorzi R, Syrgiannis Z, Bellich B, Bertoncin P, Jou IA, Brady JW, Rizzo R, Cescutti P.	Int J Biol Macromol	10.1016/j.ijbiomac.2023.127294	2023
Pathogenicity	Effects of Oral Amino Acid Supplementation on Physical Activity, Systemic Inflammation, and Quality of Life in Adult Patients with Cystic Fibrosis: A Single-Center, Randomized, Double-Blind, Placebo-Controlled Pilot Study.	Petraglia L, Iacotucci P, Ferrillo L, Cabaro S, Somma J, Lacava F, Amaranto I, Crucito S, Perrotti M, Formisano P, Rengo G, Leosco D, Carnovale V.	Nutrients	10.3390/nu17071239	2025
	Fatty acid synthesis promoted by PA1895-1897 operon delays quorum sensing activation in Pseudomonas aeruginosa.	Han L, Ren J, Xue Y, Gao J, Fu Q, Shao P, Zhu H, Zhang M, Ding F.	AMB Express	10.1186/s13568-024-01758-5	2024
	Feedback of airborne bacterial consortia to haze pollution with different PM_2.5 levels in typical mountainous terrain of Jinan, China.	Ji L, Zhang Q, Fu X, Zheng L, Dong J, Wang J, Guo S.	Sci Total Environ	10.1016/j.scitotenv.2019.133912	2019
	DddA homolog search and engineering expand sequence compatibility of mitochondrial base editing.	Mi L, Shi M, Li YX, Xie G, Rao X, Wu D, Cheng A, Niu M, Xu F, Yu Y, Gao N, Wei W, Wang X, Wang Y.	Nat Commun	10.1038/s41467-023-36600-2	2023
Pathogenicity	AR-13 reduces antibiotic-resistant bacterial burden in cystic fibrosis phagocytes and improves cystic fibrosis transmembrane conductance regulator function.	Assani K, Shrestha CL, Rinehardt H, Zhang S, Robledo-Avila F, Wellmerling J, Partida-Sanchez S, Cormet-Boyaka E, Reynolds SD, Schlesinger LS, Kopp BT.	J Cyst Fibros	10.1016/j.jcf.2018.10.010	2019
Pathogenicity	Secondhand vape exposure regulation of CFTR and immune function in cystic fibrosis.	Wisniewski BL, Shrestha M, Bojja D, Shrestha CL, Lee CS, Ozuna H, Rayner RE, Bai S, Cormet-Boyaka E, Reynolds SD, Kopp BT.	Am J Physiol Lung Cell Mol Physiol	10.1152/ajplung.00328.2024	2025
	Correction: Macrophages, but not neutrophils, are critical for proliferation of Burkholderia cenocepacia and ensuing host-damaging inflammation.	Mesureur J, Feliciano JR, Wagner N, Gomes MC, Zhang L, Blanco-Gonzalez M, van der Vaart M, O'Callaghan D, Meijer AH, Vergunst AC.	PLoS Pathog	10.1371/journal.ppat.1006795	2017
	Synthesis of a trisaccharide repeating unit of the O-antigen from Burkholderia cenocepacia and its dimer.	Bi N, Xiong C, Jin G, Guo Z, Gu G.	Carbohydr Res	10.1016/j.carres.2017.09.001	2017
Genetics	Mitochondrial genome editing: strategies, challenges, and applications.	Lim K.	BMB Rep		2024
	A LysR Family Transcriptional Regulator Modulates Burkholderia cenocepacia Biofilm Formation and Protease Production.	Wang K, Li X, Yang C, Song S, Cui C, Zhou X, Deng Y.	Appl Environ Microbiol	10.1128/aem.00202-21	2021
	Protein with negative surface charge distribution, Bnr1, shows characteristics of a DNA-mimic protein and may be involved in the adaptation of Burkholderia cenocepacia.	Dennehy R, Duggan N, Dignam S, McCormack S, Dillon E, Molony J, Romano M, Hou Y, Ardill L, Whelan MVX, Drulis-Kawa Z, O'Croinin T, Valvano MA, Berisio R, McClean S.	Microbiologyopen	10.1002/mbo3.1264	2022
	The Small RNA NcS25 Regulates Biological Amine-Transporting Outer Membrane Porin BCAL3473 in Burkholderia cenocepacia.	Sass AM, Coenye T.	mSphere	10.1128/msphere.00083-23	2023
	Employing Genomic Tools to Explore the Molecular Mechanisms behind the Enhancement of Plant Growth and Stress Resilience Facilitated by a Burkholderia Rhizobacterial Strain.	Chang YL, Chang YC, Kurniawan A, Chang PC, Liou TY, Wang WD, Chuang HW.	Int J Mol Sci	10.3390/ijms25116091	2024
Enzymology	A Possible Involvement of Sialidase in the Cell Response of the Antarctic Fungus Penicillium griseofulvum P29 to Oxidative Stress.	Abrashev R, Krumova E, Petrova P, Eneva R, Gocheva Y, Engibarov S, Miteva-Staleva J, Dishliyska V, Stoyancheva G, Spasova B, Kolyovska V, Angelova M.	Life (Basel)	10.3390/life15060926	2025
	Identification of novel small RNAs in Burkholderia cenocepacia KC-01 expressed under iron limitation and oxidative stress conditions.	Ghosh S, Dureja C, Khatri I, Subramanian S, Raychaudhuri S, Ghosh S.	Microbiology (Reading)	10.1099/mic.0.000566	2017
	Genes required for phosphosphingolipid formation in Caulobacter crescentus contribute to bacterial virulence.	Olea-Ozuna RJ, Poggio S, Bergstrom E, Osorio A, Elufisan TO, Padilla-Gomez J, Martinez-Aguilar L, Lopez-Lara IM, Thomas-Oates J, Geiger O.	PLoS Pathog	10.1371/journal.ppat.1012401	2024
	Identification by Reverse Vaccinology of Three Virulence Factors in Burkholderia cenocepacia That May Represent Ideal Vaccine Antigens.	Irudal S, Scoffone VC, Trespidi G, Barbieri G, D'Amato M, Viglio S, Pizza M, Scarselli M, Riccardi G, Buroni S.	Vaccines (Basel)	10.3390/vaccines11061039	2023
Metabolism	The microbiota-dependent tryptophan metabolite alleviates high-fat diet-induced insulin resistance through the hepatic AhR/TSC2/mTORC1 axis.	Du W, Jiang S, Yin S, Wang R, Zhang C, Yin BC, Li J, Li L, Qi N, Zhou Y, Ye BC.	Proc Natl Acad Sci U S A	10.1073/pnas.2400385121	2024
	A Thermostable Bacterial Metallohydrolase that Degrades Organophosphate Plasticizers.	Ji D, Frkic RL, Delyami J, Larsen JS, Spence MA, Jackson CJ.	Chembiochem	10.1002/cbic.202500055	2025
	Precise measurement of the fitness effects of spontaneous mutations by droplet digital PCR in Burkholderia cenocepacia.	Rana A, Patton D, Turner NT, Dillon MM, Cooper VS, Sung W.	Genetics	10.1093/genetics/iyab117	2021
	Phage-antibiotic synergy to combat multidrug resistant strains of Gram-negative ESKAPE pathogens.	Morris TC, Reyneke B, Khan S, Khan W.	Sci Rep	10.1038/s41598-025-01489-y	2025
Phylogeny	Biosorption and transformation of cadmium and lead by Staphylococcus epidermidis AS-1 isolated from industrial effluent.	Kumar A, Mukherjee G, Ahuja V, Gupta S, Tarighat MA, Abdi G.	BMC Microbiol	10.1186/s12866-024-03568-y	2024
	Bactericidal and Anti-Biofilm Activity of the FtsZ Inhibitor C109 against Acinetobacter baumannii.	Scoffone VC, Irudal S, AbuAlshaar A, Piazza A, Trespidi G, Barbieri G, Makarov V, Migliavacca R, De Rossi E, Buroni S.	Antibiotics (Basel)	10.3390/antibiotics11111571	2022
	Bioinformatics analysis of myelin-microbe interactions suggests multiple types of molecular mimicry in the pathogenesis of multiple sclerosis.	Bigdeli A, Ghaderi-Zefrehei M, Lesch BJ, Behmanesh M, Arab SS.	PLoS One	10.1371/journal.pone.0308817	2024
	CFTR Modulators Restore Acidification of Autophago-Lysosomes and Bacterial Clearance in Cystic Fibrosis Macrophages.	Badr A, Eltobgy M, Krause K, Hamilton K, Estfanous S, Daily KP, Abu Khweek A, Hegazi A, Anne MNK, Carafice C, Robledo-Avila F, Saqr Y, Zhang X, Bonfield TL, Gavrilin MA, Partida-Sanchez S, Seveau S, Cormet-Boyaka E, Amer AO.	Front Cell Infect Microbiol	10.3389/fcimb.2022.819554	2022
	Maternal Colonization Versus Nosocomial Transmission as the Source of Drug-Resistant Bloodstream Infection in an Indian Neonatal Intensive Care Unit: A Prospective Cohort Study.	Robinson ML, Johnson J, Naik S, Patil S, Kulkarni R, Kinikar A, Dohe V, Mudshingkar S, Kagal A, Smith RM, Westercamp M, Randive B, Kadam A, Babiker A, Kulkarni V, Karyakarte R, Mave V, Gupta A, Milstone AM, Manabe YC.	Clin Infect Dis	10.1093/cid/ciad282	2023
	CRISPR-like sequences association with antibiotic resistance and biofilm formation in Helicobacter pylori clinical isolates	Yousefi L, Kadkhoda H, Shirmohammadi M, Moaddab S, Ghotaslou R, Tahereh pirzadeh, Sadeghi J, Somi M, Ahangarzadeh Rezaee M, Ganbarov K, Samadi Kafil H.	Heliyon		2024
	A Phase IIa, Single-Blind, Placebo-Controlled, Parallel-Group Study to Assess Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of Brensocatib in Adults with Cystic Fibrosis.	Konstan MW, Tolle JJ, DiMango E, Flume PA, Usansky H, Teper A, Ramirez CN, Flarakos J, Basso J, Li S, Vergara M.	Clin Pharmacokinet	10.1007/s40262-025-01550-z	2025
	The BDSF quorum sensing receptor RpfR regulates Bep exopolysaccharide synthesis in Burkholderia cenocepacia via interaction with the transcriptional regulator BerB.	Steiner E, Shilling RE, Richter AM, Schmid N, Fazli M, Kaever V, Jenal U, Tolker-Nielsen T, Eberl L.	NPJ Biofilms Microbiomes	10.1038/s41522-022-00356-2	2022
	In Vitro Activity of Finafloxacin against Panels of Respiratory Pathogens.	Harding SV, Barnes KB, Hawser S, Bentley CE, Vente A.	Antibiotics (Basel)	10.3390/antibiotics12071096	2023
Phylogeny	Cervicovaginal Microbiome and HPV: A Standardized Approach to 16S/ITS NGS and Microbial Community Profiling for Viral Association	Shen-Gunther J, Xia Q, Cai H, Wang Y.	Int J Mol Sci		2025
	Impact of MgtC on the Fitness of Yersinia pseudotuberculosis.	Li P, Wang H, Sun W, Ding J.	Pathogens	10.3390/pathogens12121428	2023
	Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms.	Laudouze J, Canaan S, Gouzy A, Santucci P.	FEBS Lett	10.1002/1873-3468.70023	2025
Pathogenicity	Structural basis for sequence context-independent single-stranded DNA cytosine deamination by the bacterial toxin SsdA.	Yin L, Chen Y, Shi K, Barreto Duran E, Harris RS, Aihara H.	Nat Commun	10.1038/s41467-025-63943-9	2025
Enzymology	Outbreak of health care-associated Burkholderia cenocepacia bacteremia and infection attributed to contaminated sterile gel used for central line insertion under ultrasound guidance and other procedures.	Shaban RZ, Maloney S, Gerrard J, Collignon P, Macbeth D, Cruickshank M, Hume A, Jennison AV, Graham RMA, Bergh H, Wilson HL, Derrington P.	Am J Infect Control	10.1016/j.ajic.2017.06.025	2017
Genetics	Integrating metagenomics and culturomics to uncover the soil bacterial community in Asparagus cochinchinensis cultivation.	Yu J, Yang S, Zhang X, Liu X, Tang X, Wang L, Chen J, Luo H, Liu C, Song C.	Front Microbiol	10.3389/fmicb.2024.1467864	2024
Phylogeny	Beyond the Usual Suspects: Weeksella virosa as a Potential Human and Animal Pathogen.	Colosi IA, Toc DA, Neculicioiu VS, Panaitescu PS, Schiopu P, Pana AG, Opris RV, Baciu AM, Berar G, Botan A, Costache C.	Trop Med Infect Dis	10.3390/tropicalmed10080210	2025
Pathogenicity	Synthetic cystic fibrosis sputum medium diminishes Burkholderia cenocepacia antifungal activity against Aspergillus fumigatus independently of phenylacetic acid production.	Lightly TJ, Phung RR, Sorensen JL, Cardona ST.	Can J Microbiol	10.1139/cjm-2016-0705	2017
Genetics	Recent Discovery of Diverse Prophages Located in Genomes of Vibrio spp. and Their Implications for Bacterial Pathogenicity, Environmental Fitness, Genome Evolution, Food Safety, and Public Health.	Ou Y, Yan J, Wang Y, Chen L.	Foods	10.3390/foods14030403	2025
	Metagenomic assessment of the bacterial breastfeeding microbiome in mature milk across lactation.	Ingram K, Gregg C, Tegge A, Elison JT, Lin W, Howell BR.	Front Pediatr	10.3389/fped.2023.1275436	2023
	Exploration of phytate-mineralizing bacteria with multifarious plant growth-promoting traits.	Kaur R, Kaur S.	BioTechnologia (Pozn)	10.5114/bta.2022.116204	2022
	Production and Purification of Two Bioactive Antimicrobial Peptides Using a Two-Step Approach Involving an Elastin-Like Fusion Tag.	Pereira AM, Costa AD, Dias SC, Casal M, Machado R.	Pharmaceuticals (Basel)	10.3390/ph14100956	2021
	Assay for Protealysin-like Protease Inhibitor Activity.	Berdyshev IM, Karaseva MA, Demidyuk AIV.	Bio Protoc	10.21769/bioprotoc.4528	2022
	Engineering RsDddA as mitochondrial base editor with wide target compatibility and enhanced activity.	Cheng K, Li C, Jin J, Qian X, Guo J, Shen L, Dai Y, Zhang X, Li Z, Guan Y, Zhou F, Tang J, Zhang J, Shen B, Lou X.	Mol Ther Nucleic Acids	10.1016/j.omtn.2023.09.005	2023
	Transcriptomic Analyses to Unravel Cronobacter sakazakii Resistance Pathways.	Liu S, Song D, Liu B, Dong K, Jiang Y, Man C, Yang X, Zhao F.	Foods	10.3390/foods13172786	2024
	Efficacy of inhaled nebulised unfractionated heparin to prevent intubation or death in hospitalised patients with COVID-19: an investigator-initiated international meta-trial of randomised clinical studies.	van Haren FMP, Valle SJ, Neto AS, Schultz MJ, Laffey JG, Artigas A, Dixon B, Vilaseca AB, Barbera RA, Ismail TI, Mahrous RS, Badr M, DeNucci G, Sverdloff C, Camprubi-Rimblas M, Cosgrave DW, McNicholas B, Cody C, Curley G, Smoot TL, Staas S, Sann K, Sas C, Belani A, Hillman C, Manggala SK, Aditianingsih D, Sugiarto A, Yulianti M, Herikurniawan H, Sinto R, Auerkari AN, Permana SA, Woodcock A, Carroll M, Wilkinson T, Singh D, Shute JK, Carroll M, Page C.	EClinicalMedicine	10.1016/j.eclinm.2025.103339	2025
Metabolism	Mouse intestinal niche cells express a distinct alpha1,2-fucosylated glycan recognized by a lectin from Burkholderia cenocepacia.	Sugahara D, Kobayashi Y, Akimoto Y, Kawakami H.	Glycobiology	10.1093/glycob/cww116	2017
Metabolism	The LpxL acyltransferase is required for normal growth and penta-acylation of lipid A in Burkholderia cenocepacia.	Fathy Mohamed Y, Hamad M, Ortega XP, Valvano MA.	Mol Microbiol	10.1111/mmi.13618	2017
Pathogenicity	In vitro antimicrobial activity of ceftolozane/tazobactam against Pseudomonas aeruginosa and other non-fermenting Gram-negative bacteria in adults with cystic fibrosis.	Gramegna A, Gramegna A, Millar BC, Blasi F, Elborn JS, Downey DG, Moore JE.	J Glob Antimicrob Resist	10.1016/j.jgar.2018.03.002	2018
	A method for creating in-frame insertions of fluorescent proteins in non-model gram-negative bacteria.	Chandramowli D, Devreese B.	AMB Express	10.1186/s13568-025-01844-2	2025
	Synthesis of Mannosylated Glycodendrimers and Evaluation against BC2L-A Lectin from Burkholderia Cenocepacia.	Pifferi C, Goyard D, Gillon E, Imberty A, Renaudet O.	Chempluschem	10.1002/cplu.201600569	2017
Pathogenicity	Noninflammatory 97-amino acid High Mobility Group Box 1 derived polypeptide disrupts and prevents diverse biofilms.	Rhodes JD, Devaraj A, Robledo-Avila F, Balu S, Mashburn-Warren L, Buzzo JR, Partida-Sanchez S, Bakaletz LO, Goodman SD.	EBioMedicine	10.1016/j.ebiom.2024.105304	2024
	A distinctive family of L,D-transpeptidases catalyzing L-Ala-mDAP crosslinks in Alpha- and Betaproteobacteria.	Espaillat A, Alvarez L, Torrens G, Ter Beek J, Miguel-Ruano V, Irazoki O, Gago F, Hermoso JA, Berntsson RP, Cava F.	Nat Commun	10.1038/s41467-024-45620-5	2024
	Mutualism breakdown underpins evolutionary rescue in an obligate cross-feeding bacterial consortium.	Melero-Jimenez IJ, Sorokin Y, Merlin A, Li J, Couce A, Friedman J.	Nat Commun	10.1038/s41467-025-58742-1	2025
Metabolism	TBC1D10C is a cytoskeletal functional linker that modulates cell spreading and phagocytosis in macrophages.	Villagomez FR, Diaz-Valencia JD, Ovalle-Garcia E, Antillon A, Ortega-Blake I, Romero-Ramirez H, Cerna-Cortes JF, Rosales-Reyes R, Santos-Argumedo L, Patino-Lopez G.	Sci Rep	10.1038/s41598-021-00450-z	2021
	Conservation of Resistance-Nodulation-Cell Division Efflux Pump-Mediated Antibiotic Resistance in Burkholderia cepacia Complex and Burkholderia pseudomallei Complex Species.	Somprasong N, Yi J, Hall CM, Webb JR, Sahl JW, Wagner DM, Keim P, Currie BJ, Schweizer HP.	Antimicrob Agents Chemother	10.1128/aac.00920-21	2021
	Structure-Guided Discovery of N⁵-CAIR Mutase Inhibitors.	Belfon KKJ, Sharma N, Zigweid R, Bolejack M, Davies D, Edwards TE, Myler PJ, French JB.	Biochemistry	10.1021/acs.biochem.2c00705	2023
Metabolism	The Burkholderia cenocepacia Type VI Secretion System Effector TecA Is a Virulence Factor in Mouse Models of Lung Infection.	Loeven NA, Perault AI, Cotter PA, Hodges CA, Schwartzman JD, Hampton TH, Bliska JB.	mBio	10.1128/mbio.02098-21	2021
	Investigation of two different PACAP-38 (Pituitary Adenylate Cyclase Activating Polypeptide) formulated feeds on Atlantic salmon (Salmo salar) immune responses with Enteric Red Mouth disease (Yersinia ruckeri)	Fajei E, Rivera Mendez L, Whyte S, Velazquez J, Dantagnan P, Soto-Davila M, Rodriguez-Ramos T, Proskos E, Dixon B, Carpio Y, Estrada M, Fast M.	Comparative Immunology Reports		2025
Pathogenicity	Application of bioanalytical and computational methods in decoding the roles of glycans in host-pathogen interactions.	Le HT, Liu M, Grimes CL.	Curr Opin Chem Biol	10.1016/j.cbpa.2023.102301	2023
	Burkholderia cenocepacia K56-2 trimeric autotransporter adhesin BcaA binds TNFR1 and contributes to induce airway inflammation.	Mil-Homens D, Pinto SN, Matos RG, Arraiano C, Fialho AM.	Cell Microbiol	10.1111/cmi.12677	2017
	The cis-2-Dodecenoic Acid (BDSF) Quorum Sensing System in Burkholderia cenocepacia.	Wang M, Li X, Song S, Cui C, Zhang LH, Deng Y.	Appl Environ Microbiol	10.1128/aem.02342-21	2022
	Metabolomic profiling of Burkholderia thailandensis infection of airway epithelial cells provides insights into potential therapeutic targets.	Hicks DJ, Aiosa N, Sinha A, Jaiyesimi OA, Branda SS, Garg N.	mSystems	10.1128/msystems.00611-25	2025
	Co-Existence Slows Diversification in Experimental Populations of E. coli and P. fluorescens.	Howells G, Sezmis AL, Blake C, McDonald MJ.	Environ Microbiol	10.1111/1462-2920.70061	2025
	Structural basis for binding and transfer of heme in bacterial heme-acquisition systems.	Naoe Y, Nakamura N, Rahman MM, Tosha T, Nagatoishi S, Tsumoto K, Shiro Y, Sugimoto H.	Proteins	10.1002/prot.25386	2017
	Development of an Analysis Toolkit, AnalysisFMO, to Visualize Interaction Energies Generated by Fragment Molecular Orbital Calculations.	Tokiwa T, Nakano S, Yamamoto Y, Ishikawa T, Ito S, Sladek V, Fukuzawa K, Mochizuki Y, Tokiwa H, Misaizu F, Shigeta Y.	J Chem Inf Model	10.1021/acs.jcim.8b00649	2019
	Innovative perspectives on the discovery of small molecule antibiotics.	Cardona ST, Rahman ASMZ, Novomisky Nechcoff J.	NPJ Antimicrob Resist	10.1038/s44259-025-00089-0	2025
	Mitochondrial Fragmentation Induced by the CFTR Modulators Lumacaftor and Ivacaftor in Immortalized Cystic Fibrosis Cell Lines.	Dib C, Gonzalez PAI, Aguilar MLA, Taminelli GL, Limpias Del Valle T, Nunez NE, Karadayian AG, Santa-Coloma TA, Valdivieso AG.	Cells	10.3390/cells14201601	2025
Genetics	Multi-omic Characterization of Intraspecies Variation in Laboratory and Natural Environments.	Behringer MG.	mSystems	10.1128/msystems.00764-21	2021
	Prediction and Validation of a Druggable Site on Virulence Factor of Drug Resistant Burkholderia cenocepacia*.	Lal K, Bermeo R, Cramer J, Vasile F, Ernst B, Imberty A, Bernardi A, Varrot A, Belvisi L.	Chemistry	10.1002/chem.202100252	2021
	Tri- and tetravalent mannoclusters cross-link and aggregate BC2L-A lectin from Burkholderia cenocepacia.	Csavas M, Malinovska L, Perret F, Gyurko M, Illyes ZT, Wimmerova M, Borbas A.	Carbohydr Res	10.1016/j.carres.2016.11.008	2017
Phylogeny	Quorum sensing in bacteria: in silico protein analysis, ecophysiology, and reconstruction of their evolutionary history.	de la Fuente I, Manzano-Morales S, Sanz D, Prieto A, Barriuso J.	BMC Genomics	10.1186/s12864-024-10355-6	2024
	[Multilocus sequence analysis, biofilm production, antibiotic susceptibility and synergy tests of Burkholderia species in patients with and without cystic fibrosis].	Akisoglu O, Engin D, Saricam S, Mustak HK, Sener B, Hascelik G.	Mikrobiyol Bul	10.5578/mb.67730	2019
Pathogenicity	The Burkholderia cenocepacia peptidoglycan-associated lipoprotein is involved in epithelial cell attachment and elicitation of inflammation.	Dennehy R, Romano M, Ruggiero A, Mohamed YF, Dignam SL, Mujica Troncoso C, Callaghan M, Valvano MA, Berisio R, McClean S.	Cell Microbiol	10.1111/cmi.12691	2017
	A Rare Case of Escherichia coli Chest Wall Abscess With Rib Osteomyelitis in a Patient With Crohn's Disease.	Dadlani A, Bandikatla S, Koch JA.	Cureus	10.7759/cureus.13860	2021
	Diabetic foot infection caused by bacteria of the Burkholderia cepacia complex: report of an unusual case and a scoping literature review.	Paes Leme RC, Chaves JRE, Goncalves LCS, Alvim LC, Almeida JRC, Reno LDC.	Rev Inst Med Trop Sao Paulo	10.1590/s1678-9946202264036	2022
	Development of an Sce-I mutagenesis system for Burkholderia cepacia complex strains.	Abdu A, Juarez-Lara G, Dennis JJ.	J Microbiol Methods	10.1016/j.mimet.2018.01.011	2018
	Lung transplantation in cystic fibrosis patients with difficult to treat lung infections.	Dupont L.	Curr Opin Pulm Med	10.1097/mcp.0000000000000431	2017
	A Polyclonal Antibody Raised against the Burkholderia cenocepacia OmpA-like Protein BCAL2645 Impairs the Bacterium Adhesion and Invasion of Human Epithelial Cells In Vitro.	Seixas AMM, Sousa SA, Feliciano JR, Gomes SC, Ferreira MR, Moreira LM, Leitao JH.	Biomedicines	10.3390/biomedicines9121788	2021
	Clinical, Laboratory and Bacterial Profile of Spontaneous Bacterial Peritonitis in Vietnamese Patients with Liver Cirrhosis.	Nguyen LC, Lo TT, La HD, Doan HT, Le NT.	Hepat Med	10.2147/hmer.s369966	2022
Pathogenicity	Burkholderia cenocepacia-host cell contact controls the transcription activity of the trimeric autotransporter adhesin BCAM2418 gene.	Pimenta AI, Mil-Homens D, Fialho AM.	Microbiologyopen	10.1002/mbo3.998	2020
	Vibrio cholerae integrates interspecies quorum-sensing signals to regulate virulence.	Bosire EM, Adams MC, Pavinski Bitar PD, Murphy SG, Shin J-H, Chappie JS, Dorr T, Altier C.	mBio	10.1128/mbio.01537-25	2025
	Using dendritic cells to evaluate how Burkholderia cenocepacia clonal isolates from a chronically infected cystic fibrosis patient subvert immune functions.	Guadalupe Cabral M, Pereira M, Silva Z, Iria I, Coutinho C, Lopes A, Sa-Correia I, Videira PA.	Med Microbiol Immunol	10.1007/s00430-016-0488-4	2017
	Functional diversity of c-di-GMP receptors in prokaryotic and eukaryotic systems.	Khan F, Jeong GJ, Tabassum N, Kim YM.	Cell Commun Signal	10.1186/s12964-023-01263-5	2023
	Antibacterial Activity of Metergoline Analogues: Revisiting the Ergot Alkaloid Scaffold for Antibiotic Discovery.	Johnson JW, Ellis MJ, Piquette ZA, MacNair C, Carfrae L, Bhando T, Ritchie NE, Saliba P, Brown ED, Magolan J.	ACS Med Chem Lett	10.1021/acsmedchemlett.1c00648	2022
	De novo biosynthesis and nicotinamide biotransformation of nicotinamide mononucleotide by engineered yeast cells.	Ren Y, Han B, Wang S, Wang X, Liu Q, Cai M.	Microb Biotechnol	10.1111/1751-7915.70048	2024
	Septic Transfusion Reactions Involving Burkholderia cepacia Complex: A Review.	Salamanca-Pachon M, Guayacan-Fuquene NI, Garcia-Otalora MA.	Microorganisms	10.3390/microorganisms12010040	2023
Metabolism	The biofilm of Burkholderia cenocepacia H111 contains an exopolysaccharide composed of l-rhamnose and l-mannose: Structural characterization and molecular modelling.	Bellich B, Jou IA, Buriola C, Ravenscroft N, Brady JW, Fazli M, Tolker-Nielsen T, Rizzo R, Cescutti P.	Carbohydr Res	10.1016/j.carres.2020.108231	2021
	Elexacaftor-tezacaftor-ivacaftor in patients with cystic fibrosis ineligible for clinical trials: a 24-week observational study.	Fila L, Grandcourtova A, Bilkova A, Drevinek P.	Front Pharmacol	10.3389/fphar.2023.1178009	2023
	The evolution of lung transplantation for cystic fibrosis: A 2017 update.	Snell G, Reed A, Stern M, Hadjiliadis D.	J Cyst Fibros	10.1016/j.jcf.2017.06.008	2017
	Mycobacterium abscessus persistence in the face of Pseudomonas aeruginosa antagonism.	Gupta R, Schuster M, Rohde KH.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1569331	2025
	Biocontrol of Burkholderia cepacia complex bacteria and bacterial phytopathogens by Bdellovibrio bacteriovorus.	McNeely D, Chanyi RM, Dooley JS, Moore JE, Koval SF.	Can J Microbiol	10.1139/cjm-2016-0612	2017
	Complete Genome Sequence of Burkholderia cenocepacia CR318, a Phosphate-Solubilizing Bacterium Isolated from Corn Root.	Zekic F, Weselowski B, Yuan ZC.	Genome Announc	10.1128/genomea.00490-17	2017
Pathogenicity	Eradication and phenotypic tolerance of Burkholderia cenocepacia biofilms exposed to atmospheric pressure non-thermal plasma.	Alshraiedeh NH, Higginbotham S, Flynn PB, Alkawareek MY, Tunney MM, Gorman SP, Graham WG, Gilmore BF.	Int J Antimicrob Agents	10.1016/j.ijantimicag.2016.03.004	2016
	Dynamic visualization of extracellular matrix components in S. aureus colony biofilms reveals functional amyloids leading to the formation of cap-like structures.	Zhang T, Bar J, Risberg L, Gomez Mejia A, Hammar H, Loffler S, Otzen DE, Andreasen M, Meyer RL, Melican K, Zinkernagel AS, Richter-Dahlfors A.	Biofilm	10.1016/j.bioflm.2025.100318	2025
Metabolism	The effect of mutation in the clpX gene on the synthesis of N-acyl-homoserine lactones and other properties of Burkholderia cenocepacia 370.	Veselova MA, Romanova YM, Lipasova VA, Koksharova OA, Zaitseva YV, Chernukha MU, Gintsburg AL, Khmel IA.	Microbiol Res	10.1016/j.micres.2016.03.009	2016
Metabolism	Biofilms produced by Burkholderia cenocepacia: influence of media and solid supports on composition of matrix exopolysaccharides.	Pellizzoni E, Ravalico F, Scaini D, Delneri A, Rizzo R, Cescutti P.	Microbiology (Reading)	10.1099/mic.0.000214	2016
	Differential effects of Th17 cytokines during the response of neutrophils to Burkholderia cenocepacia outer membrane protein A.	Nady S, Abdel-Rahman M, Sousa SA, LEITaO JH, Morad M, El-Hennamy RE.	Cent Eur J Immunol	10.5114/ceji.2019.92800	2019
Metabolism	An electron transfer flavoprotein is essential for viability and its depletion causes a rod-to-sphere change in Burkholderia cenocepacia.	Bloodworth RAM, Zlitni S, Brown ED, Cardona ST.	Microbiology (Reading)	10.1099/mic.0.000156	2015
Metabolism	The Crystal Structure of Burkholderia cenocepacia DfsA Provides Insights into Substrate Recognition and Quorum Sensing Fatty Acid Biosynthesis.	Spadaro F, Scoffone VC, Chiarelli LR, Fumagalli M, Buroni S, Riccardi G, Forneris F.	Biochemistry	10.1021/acs.biochem.6b00178	2016
Transcriptome	Goblet cell breakdown: transcriptomics reveals Acinetobacter baumannii early and robust inflammatory response in differentiated human bronchial epithelial cells.	Scribano D, Tito C, Tagueha AD, Pasqua M, De Angelis L, Fazi F, Limongi D, De Angelis M, Nencioni L, Palamara AT, Ambrosi C.	J Biomed Sci	10.1186/s12929-025-01159-1	2025
	The Achromobacter type 3 secretion system drives pyroptosis and immunopathology via independent activation of NLRC4 and NLRP3 inflammasomes.	Turton K, Parks HJ, Zarodkiewicz P, Hamad MA, Dwane R, Parau G, Ingram RJ, Coll RC, Bryant CE, Valvano MA.	Cell Rep	10.1016/j.celrep.2023.113012	2023
	Identification of Burkholderia cenocepacia non-coding RNAs expressed during Caenorhabditis elegans infection.	Pita T, Feliciano JR, Leitao JH.	Appl Microbiol Biotechnol	10.1007/s00253-023-12530-3	2023
Pathogenicity	Characterization of Volatile Organic Compounds Emitted from Endophytic Burkholderia cenocepacia ETR-B22 by SPME-GC-MS and Their Inhibitory Activity against Various Plant Fungal Pathogens.	Chen JH, Xiang W, Cao KX, Lu X, Yao SC, Hung D, Huang RS, Li LB.	Molecules	10.3390/molecules25173765	2020
	Mechanisms of antimicrobial resistance in biofilms.	Liu HY, Prentice EL, Webber MA.	NPJ Antimicrob Resist	10.1038/s44259-024-00046-3	2024
Metabolism	Gene expression reprogramming of Pseudomonas alloputida in response to arginine through the transcriptional regulator ArgR.	Molina-Henares MA, Ramos-Gonzalez MI, Rinaldo S, Espinosa-Urgel M.	Microbiology (Reading)	10.1099/mic.0.001449	2024
Genetics	Isolation, complete genome sequencing and in silico genome mining of Burkholderia for secondary metabolites.	Alam K, Zhao Y, Lu X, Gong K, Zhong L, Hao J, Islam MM, Islam S, Li G, Zhang Y, Li R, Li A.	BMC Microbiol	10.1186/s12866-022-02692-x	2022
	Selectivity of original C-hexopyranosyl calix[4]arene conjugates towards lectins of different origin.	Kasakova M, Malinovska L, Klejch T, Hlavackova M, Dvorakova H, Fujdiarova E, Rottnerova Z, Matatkova O, Lhotak P, Wimmerova M, Moravcova J.	Carbohydr Res	10.1016/j.carres.2018.08.012	2018
Proteome	Proteome Changes Induced by Iprodione Exposure in the Pesticide-Tolerant Pseudomonas sp. C9 Strain Isolated from a Biopurification System.	Donoso-Pinol P, Briceno G, Evaristo JAM, Nogueira FCS, Schalchli H, Diez MC.	Int J Mol Sci	10.3390/ijms251910471	2024
Metabolism	Burkholderia cenocepacia H111 Produces a Water-Insoluble Exopolysaccharide in Biofilm: Structural Determination and Molecular Modelling.	Bellich B, Jou IA, Caterino M, Rizzo R, Ravenscroft N, Fazli M, Tolker-Nielsen T, Brady JW, Cescutti P.	Int J Mol Sci	10.3390/ijms21051702	2020
	DNA Repair and Mutagenesis of ADP-Ribosylated DNA by Pierisin.	Kawanishi M, Yagi T, Totsuka Y, Wakabayashi K.	Toxins (Basel)	10.3390/toxins16080331	2024
	Clinical Isolates of Antimicrobial-Resistant Enterobacter Species Can Persist in Human Macrophages Without Replication and Overt Cellular Cytotoxicity.	Parau G, Parks HJ, Anderson AJG, Bisaro F, Garcia-Romero I, Gilmore MC, Korankye SO, Marshall H, Valvano MA.	J Infect Dis	10.1093/infdis/jiaf099	2025
	Modeling glycans with AlphaFold 3: capabilities, caveats, and limitations.	Huang C, Kannan N, Moremen KW.	Glycobiology	10.1093/glycob/cwaf048	2025
	Diffusible signal factors (DSFs) bind and repress VirF, the leading virulence activator of Shigella flexneri.	Trirocco R, Pasqua M, Tramonti A, Colonna B, Paiardini A, Prosseda G.	Sci Rep	10.1038/s41598-023-40023-w	2023
	Autoinducing peptides regulate antibiotic production to potentially shape root microbiome.	Chen N, Cai P, Lin X, Song ZM, He J, Li Z, Li Z, Zhang D, Song Y, Li YX.	Sci Adv	10.1126/sciadv.adw5076	2025
	A metagenomic analysis coupled with oligotrophic enrichment approach for detecting specified microorganisms in potable groundwater samples	Daddy Gaoh S, Alusta P, Lee Y, Hussong D, Marasa B, Ahn Y.	Front Microbiol		2025
	Metagenomic sequencing for identification of nontuberculous mycobacteria and other pathogens in patients with mixed infection of the lung	Yu J, Lv X, Wang Q, Gao M, Li W.	Front Cell Infect Microbiol		2025
Metabolism	[The Effect of Introduction of the Heterologous Gene Encoding the N-acyl-homoserine Lactonase (aiiA) on the Properties of Burkholderia cenocepacia 370].	Plyuta VA, Lipasova VA, Koksharova OA, Veselova MA, Kuznetsov AE, Khmel IA.	Genetika	10.1134/s1022795415080062	2015
	IFN-gamma licenses normal and pathogenic ALPK1/TIFA pathway in human monocytes.	Martin A, Caron S, Marcotte M, Bronnec P, Garneret E, Martel N, Maalouf G, Seve P, Saadoun D, Jamilloux Y, Henry T.	iScience	10.1016/j.isci.2024.111563	2025
	High-Throughput Screen Reveals the Structure-Activity Relationship of the Antimicrobial Lasso Peptide Ubonodin.	Thokkadam A, Do T, Ran X, Brynildsen MP, Yang ZJ, Link AJ.	ACS Cent Sci	10.1021/acscentsci.2c01487	2023
Genetics	Bioinformatic strategies in metagenomics of chronic prostatitis.	Davasaz Tabrizi E, Sevil M, Arican E.	World J Urol	10.1007/s00345-025-05514-7	2025
Metabolism	Metabolomic profiling of Burkholderia cenocepacia in synthetic cystic fibrosis sputum medium reveals nutrient environment-specific production of virulence factors.	Jaiyesimi OA, McAvoy AC, Fogg DN, Garg N.	Sci Rep	10.1038/s41598-021-00421-4	2021
	Airway Mucins Inhibit Oxidative and Non-Oxidative Bacterial Killing by Human Neutrophils.	Cantin AM, Ouellet C, Cloutier A, McDonald PP.	Front Pharmacol	10.3389/fphar.2020.554353	2020
Metabolism	Quantification of type VI secretion system activity in macrophages infected with Burkholderia cenocepacia.	Aubert DF, Hu S, Valvano MA.	Microbiology (Reading)	10.1099/mic.0.000174	2015
	Burkholderia pseudomallei lectins: occurrence and expression.	Koh SF, Tay ST, Puthucheary SD.	Trop Biomed		2016
Pathogenicity	Rocket-miR, a translational launchpad for miRNA-based antimicrobial drug development.	Neff SL, Hampton TH, Koeppen K, Sarkar S, Latario CJ, Ross BD, Stanton BA.	mSystems	10.1128/msystems.00653-23	2023
	Survival dynamics of cystic fibrosis-related Gram-negative bacterial pathogens (Pseudomonas aeruginosa and Burkholderia cenocepacia) in Dead Sea and Atlantic Ocean waters.	Shteinberg M, Kis-Papo T, Millar BC, Rendall JC, Downey DG, Elborn JS, Moore JE.	J Water Health	10.2166/wh.2015.157	2015
Pathogenicity	An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases the fluoroquinolone sensitivity of P. aeruginosa.	Koeppen K, Hampton TH, Barnaby R, Roche C, Gerber SA, Goo YA, Cho BK, Vermilyea DM, Hogan DA, Stanton BA.	Am J Physiol Lung Cell Mol Physiol	10.1152/ajplung.00150.2022	2023
	Glycomimetic antagonists of BC2L-C lectin: insights from molecular dynamics simulations.	Antonini G, Civera M, Lal K, Mazzotta S, Varrot A, Bernardi A, Belvisi L.	Front Mol Biosci	10.3389/fmolb.2023.1201630	2023
Transcriptome	Adaptation mechanisms of Brucella abortus to low magnesium ion stress.	Wang H, Lv L, Huang Y, Jiang H, Yang X, Ding J, Zhu L, Xu L, Sang H, Jiang J, Wang N, Li P.	BMC Vet Res	10.1186/s12917-025-04831-8	2025
	Response Surface Methodology Application for Bacteriophage-Antibiotic Antibiofilm Activity Optimization.	Grygorcewicz B, Glizniewicz M, Olszewska P, Milek D, Czajkowski A, Serwin N, Cecerska-Heryc E, Rakoczy R.	Microorganisms	10.3390/microorganisms11092352	2023
	MakC and MakD are two proteins associated with a tripartite toxin of Vibrio cholerae.	Bodra N, Toh E, Nadeem A, Wai SN, Persson K.	Front Microbiol	10.3389/fmicb.2024.1457850	2024
	Chemical Composition, Biological Activity, and Application of Rosa damascena Essential Oil as an Antimicrobial Agent in Minimally Processed Eggplant Inoculated with Salmonella enterica.	Veresova A, Vukic MD, Vukovic NL, Terentjeva M, Ban Z, Li L, Bianchi A, Kollar J, Ben Saad R, Ben Hsouna A, Elizondo-Luevano JH, Kluz MI, Cmikova N, Garzoli S, Kacaniova M.	Foods	10.3390/foods13223579	2024
Phylogeny	Research on the establishment and application of protein fingerprint spectrum database of Burkholderia pseudomallei in Hainan Province China.	Huang MH, Wu H, Liu LL, Wang XM.	New Microbes New Infect	10.1016/j.nmni.2021.100938	2021
	Antibacterial properties of the pituitary adenylate cyclase-activating polypeptide: A new human antimicrobial peptide.	Debbabi S, Groleau MC, Letourneau M, Narayanan C, Gosselin LL, Iddir M, Gagnon J, Doucet N, Deziel E, Chatenet D.	PLoS One	10.1371/journal.pone.0207366	2018
	TssA from Burkholderia cenocepacia: expression, purification, crystallization and crystallographic analysis.	Owen HJ, Sun R, Ahmad A, Sedelnikova SE, Baker PJ, Thomas MS, Rice DW.	Acta Crystallogr F Struct Biol Commun	10.1107/s2053230x18009706	2018
Metabolism	A Burkholderia Type VI Effector Deamidates Rho GTPases to Activate the Pyrin Inflammasome and Trigger Inflammation.	Aubert DF, Xu H, Yang J, Shi X, Gao W, Li L, Bisaro F, Chen S, Valvano MA, Shao F.	Cell Host Microbe	10.1016/j.chom.2016.04.004	2016
Phylogeny	Impact of influenza virus infection on lung microbiome in adults with severe pneumonia.	Zhou Y, Du J, Wu JQ, Zhu QR, Xie MZ, Chen LY, Liu YQ, Li W, Zhou TF, Lu QB.	Ann Clin Microbiol Antimicrob	10.1186/s12941-023-00590-2	2023
Enzymology	Lung transplant for a patient with cystic fibrosis and active Burkholderia Cenocepacia pneumonia.	Salizzoni S, Pilewski J, Toyoda Y.	Exp Clin Transplant		2014
	Harnessing the Diversity of Burkholderia spp. Prophages for Therapeutic Potential.	Nordstrom HR, Griffith MP, Rangachar Srinivasa V, Wallace NR, Li A, Cooper VS, Shields RK, Van Tyne D.	Cells	10.3390/cells13050428	2024
	Searching for Frataxin Function: Exploring the Analogy with Nqo15, the Frataxin-like Protein of Respiratory Complex I from Thermus thermophilus.	Doni D, Cavallari E, Noguera ME, Gentili HG, Cavion F, Parisi G, Fornasari MS, Sartori G, Santos J, Bellanda M, Carbonera D, Costantini P, Bortolus M.	Int J Mol Sci	10.3390/ijms25031912	2024
Enzymology	Prevalence of Burkholderia cepacia complex species in cystic fibrosis patients in Argentina during the period 2011-2015.	Cipolla L, Rocca F, Martinez C, Aguerre L, Barrios R, Prieto M.	Enferm Infecc Microbiol Clin (Engl Ed)	10.1016/j.eimc.2017.09.002	2018
Metabolism	Investigation of the multifaceted iron acquisition strategies of Burkholderia cenocepacia.	Tyrrell J, Whelan N, Wright C, Sa-Correia I, McClean S, Thomas M, Callaghan M.	Biometals	10.1007/s10534-015-9840-1	2015
Cultivation	Evaluation of Three Culture Media for Isolation of Burkholderia cepacia Complex from Respiratory Samples of Patients with Cystic Fibrosis.	Marrs ECL, Perry A, Perry JD.	Microorganisms	10.3390/microorganisms9122604	2021
Pathogenicity	(R)-Roscovitine and CFTR modulators enhance killing of multi-drug resistant Burkholderia cenocepacia by cystic fibrosis macrophages.	Shrestha CL, Zhang S, Wisniewski B, Hafner S, Elie J, Meijer L, Kopp BT.	Sci Rep	10.1038/s41598-020-78817-x	2020
	Hitching a Ride in the Phyllosphere: Surfactant Production of Pseudomonas spp. Causes Co-swarming of Pantoea eucalypti 299R.	Kunzler M, Schlechter RO, Schreiber L, Remus-Emsermann MNP.	Microb Ecol	10.1007/s00248-024-02381-4	2024
	Computational and experimental mapping of the allosteric network of two manganese ABC transporters.	Duman O, Kuznetsova A, Levanon NL, Grupper M, Ersoy AA, Acar B, Kessel A, Ben-Tal N, Lewinson O, Haliloglu T.	Protein Sci	10.1002/pro.70039	2025
	A machine learning model trained on a high-throughput antibacterial screen increases the hit rate of drug discovery.	Rahman ASMZ, Liu C, Sturm H, Hogan AM, Davis R, Hu P, Cardona ST.	PLoS Comput Biol	10.1371/journal.pcbi.1010613	2022
Genetics	The Effect of 2-Thiocyanatopyridine Derivative 11026103 on Burkholderia Cenocepacia: Resistance Mechanisms and Systemic Impact.	Nunvar J, Hogan AM, Buroni S, Savina S, Makarov V, Cardona ST, Drevinek P.	Antibiotics (Basel)	10.3390/antibiotics8040159	2019
	Identification of Key Factors for Anoxic Survival of B. cenocepacia H111.	Paszti S, Vitale A, Liu Y, Braunwalder R, Kalawong R, Biner O, Pessi G, Eberl L.	Int J Mol Sci	10.3390/ijms23094560	2022
	Draft Genome Sequence of Burkholderia cenocepacia Strain CEIB S5-2, a Methyl Parathion- and p-Nitrophenol-Degrading Bacterium, Isolated from Agricultural Soils in Morelos, Mexico.	Martinez-Ocampo F, Fernandez Lopez MG, Lozano-Aguirre Beltran LF, Popoca-Ursino EC, Ortiz-Hernandez ML, Sanchez-Salinas E, Ramos Quintana F, Villalobos-Lopez MA, Dantan-Gonzalez E.	Genome Announc	10.1128/genomea.00220-16	2016
	Prevalence of Burkholderia species, including members of Burkholderia cepacia complex, among UK cystic and non-cystic fibrosis patients.	Kenna DTD, Lilley D, Coward A, Martin K, Perry C, Pike R, Hill R, Turton JF.	J Med Microbiol	10.1099/jmm.0.000458	2017
Proteome	CRISPRi-Mediated Silencing of Burkholderia O-Linked Glycosylation Systems Enables the Depletion of Glycosylation Yet Results in Modest Proteome Impacts.	Lewis JM, Scott NE.	J Proteome Res	10.1021/acs.jproteome.2c00790	2023
	Development of an Engineered Bacterial Endophyte: Promoting Plant Growth Through Pyrroloquinoline Quinone (PQQ) Synthesis.	Fang T, Lo SC, Yu YN, Sou NL, Hung SW, Peng JH, Chiang EI, Huang CC.	Microorganisms	10.3390/microorganisms13020293	2025
Pathogenicity	Engineering a bacterial toxin deaminase from the DYW-family into a novel cytosine base editor for plants and mammalian cells.	Zhang D, Parth F, da Silva LM, Ha TC, Schambach A, Boch J.	Genome Biol	10.1186/s13059-025-03478-w	2025
Metabolism	Characterization of a novel two-component system in Burkholderia cenocepacia.	Merry CR, Perkins M, Mu L, Peterson BK, Knackstedt RW, Weingart CL.	Curr Microbiol	10.1007/s00284-014-0744-z	2015
	Chimerolectins: Classification, structural architecture, and functional perspectives	Pinto-Junior V, Cavada B, Nascimento K.	Protein Sci		2025
	Parallel evolution of small colony variants in Burkholderia cenocepacia biofilms.	Cooper VS, Staples RK, Traverse CC, Ellis CN.	Genomics	10.1016/j.ygeno.2014.09.007	2014
	Clinical characteristics and prognosis of pneumonia-related bloodstream infections in the intensive care unit: a single-center retrospective study.	Liu Y, Sun T, Cai Y, Zhai T, Huang L, Zhang Q, Wang C, Chen H, Huang X, Li M, Xia J, Gu S, Guo L, Yang B, Wu X, Lu B, Zhan Q.	Front Public Health	10.3389/fpubh.2023.1249695	2023
	Harnessing hypoxia: bacterial adaptation and chronic infection in cystic fibrosis.	Carey CJ, Duggan N, Drabinska J, McClean S.	FEMS Microbiol Rev	10.1093/femsre/fuaf018	2025
	Coinfection and superinfection in ICU critically ill patients with severe COVID-19 pneumonia and influenza pneumonia: are the pictures different?	Chen Z, Zhan Q, Huang L, Wang C.	Front Public Health	10.3389/fpubh.2023.1195048	2023
	Previously unexplored etiology for femoral head necrosis: Metagenomics detects no pathogens in necrotic femoral head tissue.	Liu C, Li W, Zhang C, Pang F, Wang DW.	World J Clin Cases	10.12998/wjcc.v10.i7.2138	2022
Metabolism	Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation.	Walpole GFW, Plumb JD, Chung D, Tang B, Boulay B, Osborne DG, Piotrowski JT, Catz SD, Billadeau DD, Grinstein S, Jaumouille V.	Cell Rep	10.1016/j.celrep.2020.107721	2020
	Predicting Salmonella MIC and Deciphering Genomic Determinants of Antibiotic Resistance and Susceptibility.	Ayoola MB, Das AR, Krishnan BS, Smith DR, Nanduri B, Ramkumar M.	Microorganisms	10.3390/microorganisms12010134	2024
	Monoclonal antibodies that target extracellular DNABII proteins or the type IV pilus of nontypeable Haemophilus influenzae (NTHI) worked additively to disrupt 2-genera biofilms.	Jurcisek JA, Hofer LK, Goodman SD, Bakaletz LO.	Biofilm	10.1016/j.bioflm.2022.100096	2022
	Insertion sequences related to ISAjo2 target pdif and dif sites and belong to a new IS family, the IS1202 family.	Harmer CJ, Pong CH, Hall RM.	Microb Genom	10.1099/mgen.0.000953	2023
Metabolism	Antimicrobial properties of an oxidizer produced by Burkholderia cenocepacia P525.	Hunter WJ, Manter DK.	Curr Microbiol	10.1007/s00284-013-0515-2	2014
Pathogenicity	Combination antimicrobial susceptibility testing of Burkholderia cepacia complex: significance of species.	Abbott FK, Milne KE, Stead DA, Gould IM.	Int J Antimicrob Agents	10.1016/j.ijantimicag.2016.07.020	2016
Metabolism	Low iron-induced small RNA BrrF regulates central metabolism and oxidative stress responses in Burkholderia cenocepacia.	Sass AM, Coenye T.	PLoS One	10.1371/journal.pone.0236405	2020
	Functional relocation of the maize chloroplast atpB gene to the nucleus restores photosynthetic competence to a gene-edited non-photosynthetic mutant.	Mangu VR, Jenkins K, Pratt A, Boltz KA, Pazouki L, Hui AY, Mookkan M, Staub JM.	Plant Biotechnol J	10.1111/pbi.70175	2025
Pathogenicity	Negative interactions and virulence differences drive the dynamics in multispecies bacterial infections.	Schmitz DA, Allen RC, Kummerli R.	Proc Biol Sci	10.1098/rspb.2023.1119	2023
Metabolism	Protein profiling analyses of the outer membrane of Burkholderia cenocepacia reveal a niche-specific proteome.	Liu H, Ibrahim M, Qiu H, Kausar S, Ilyas M, Cui Z, Hussain A, Li B, Waheed A, Zhu B, Xie G.	Microb Ecol	10.1007/s00248-014-0460-z	2015
Pathogenicity	Identification of synergists that potentiate the action of polymyxin B against Burkholderia cenocepacia.	Loutet SA, El-Halfawy OM, Jassem AN, Lopez JM, Medarde AF, Speert DP, Davies JE, Valvano MA.	Int J Antimicrob Agents	10.1016/j.ijantimicag.2015.05.010	2015
Metabolism	The SPLUNC1-betaENaC complex prevents Burkholderia cenocepacia invasion in normal airway epithelia.	Ahmad S, Kim CSK, Tarran R.	Respir Res	10.1186/s12931-020-01454-5	2020
	A study on the oral and cloacal bacterial flora of Mugger crocodiles (Crocodylus palustris) in the Negour protected area, Iran.	Gholamhosseini A, Sharifiyazdi H, Rakhshaninejad M, Soltanian S, Salighehzadeh R, Kordestani H.	Vet Res Forum	10.30466/vrf.2019.108417.2571	2021
Pathogenicity	Involvement of toxin-antitoxin modules in Burkholderia cenocepacia biofilm persistence.	Van Acker H, Sass A, Dhondt I, Nelis HJ, Coenye T.	Pathog Dis	10.1111/2049-632x.12177	2014
	Draft Genome Sequence of Burkholderia cenocepacia Strain 869T2, a Plant-Beneficial Endophytic Bacterium.	Ho YN, Huang CC.	Genome Announc	10.1128/genomea.01327-15	2015
	Biological control of Alternaria alternata causing leaf spot disease of Aloe vera using two strains of rhizobacteria	Ghosh R, Barman S, Khatun J, Mandal NC.	Biol Control	10.1016/j.biocontrol.2016.03.001	2016
Metabolism	Antagonistic interactions subdue inter-species green-beard cooperation in bacteria.	Sathe S, Kummerli R.	J Evol Biol	10.1111/jeb.13666	2020
	A significant antibiofilm and antimicrobial activity of chitosan-polyacrylic acid nanoparticles against pathogenic bacteria.	Al-Fawares O, Alshweiat A, Al-Khresieh RO, Alzarieni KZ, Rashaid AHB.	Saudi Pharm J	10.1016/j.jsps.2023.101918	2024
Metabolism	The attenuated virulence of a Burkholderia cenocepacia paaABCDE mutant is due to inhibition of quorum sensing by release of phenylacetic acid.	Pribytkova T, Lightly TJ, Kumar B, Bernier SP, Sorensen JL, Surette MG, Cardona ST.	Mol Microbiol	10.1111/mmi.12771	2014
	Burkholderia cenocepacia Induces Macropinocytosis to Enter Macrophages.	Rosales-Reyes R, Sanchez-Gomez C, Ortiz-Navarrete V, Santos-Preciado JI.	Biomed Res Int	10.1155/2018/4271560	2018
	A markerless deletion method for genetic manipulation of Burkholderia cenocepacia and other multidrug-resistant gram-negative bacteria.	Aubert DF, Hamad MA, Valvano MA.	Methods Mol Biol	10.1007/978-1-4939-1261-2_18	2014
Pathogenicity	Comparative Evolutionary Patterns of Burkholderia cenocepacia and B. multivorans During Chronic Co-infection of a Cystic Fibrosis Patient Lung.	Hassan AA, Dos Santos SC, Cooper VS, Sa-Correia I.	Front Microbiol	10.3389/fmicb.2020.574626	2020
	Isolation, Identification, and Biocontrol Mechanisms of Endophytic Burkholderia arboris DHR18 from Rubber Tree against Red Root Rot Disease.	Meng X, Luo Y, Zhao X, Fu Y, Zou L, Cai H, Zhou Y, Tu M.	Microorganisms	10.3390/microorganisms12091793	2024
	4-Hydroxy-3-methyl-2(1H)-quinolone, originally discovered from a Brassicaceae plant, produced by a soil bacterium of the genus Burkholderia sp.: determination of a preferred tautomer and antioxidant activity.	Li D, Oku N, Shinozaki Y, Kurokawa Y, Igarashi Y.	Beilstein J Org Chem	10.3762/bjoc.16.124	2020
Phylogeny	Burkholderia cepacia complex in cystic fibrosis in a Brazilian reference center.	Dentini P, Marson FAL, Bonadia LC, Bertuzzo CS, Ribeiro AF, Levy CE, Ribeiro JD.	Med Microbiol Immunol	10.1007/s00430-017-0521-2	2017
	Molecular Characterization of the Burkholderia cenocepacia dcw Operon and FtsZ Interactors as New Targets for Novel Antimicrobial Design.	Trespidi G, Scoffone VC, Barbieri G, Riccardi G, De Rossi E, Buroni S.	Antibiotics (Basel)	10.3390/antibiotics9120841	2020
Enzymology	Kinetic characterization of an oxidative, cooperative HMG-CoA reductase from Burkholderia cenocepacia.	Schwarz BH, Driver J, Peacock RB, Dembinski HE, Corson MH, Gordon SS, Watson JM.	Biochim Biophys Acta	10.1016/j.bbapap.2013.11.015	2014
Pathogenicity	Antimicrobial susceptibility patterns of respiratory Gram-negative bacterial isolates from COVID-19 patients in Switzerland.	Gysin M, Acevedo CT, Haldimann K, Bodendoerfer E, Imkamp F, Bulut K, Buehler PK, Brugger SD, Becker K, Hobbie SN.	Ann Clin Microbiol Antimicrob	10.1186/s12941-021-00468-1	2021
	Extending evolutionary forecasts across bacterial species.	Pentz JT, Biswas A, Alsaed B, Lind PA.	Proc Biol Sci	10.1098/rspb.2024.2312	2024
	Amino Acid-Induced Chemotaxis Plays a Key Role in the Adaptation of Vibrio harveyi from Seawater to the Muscle of the Host Fish.	Zhang X, Zhang Z, Yan Q, Du Z, Zhao L, Qin Y.	Microorganisms	10.3390/microorganisms12071292	2024
	Behavioral Cooperation or Conflict of Human Intestinal Roundworms and Microbiomes: A Bio-Activity Perspective.	Khazaei M, Parsasefat M, Bahar A, Tahmasebi H, Oksenych V.	Cells	10.3390/cells14070556	2025
Metabolism	Elucidation of the Burkholderia cenocepacia hopanoid biosynthesis pathway uncovers functions for conserved proteins in hopanoid-producing bacteria.	Schmerk CL, Welander PV, Hamad MA, Bain KL, Bernards MA, Summons RE, Valvano MA.	Environ Microbiol	10.1111/1462-2920.12509	2015
	Bio-informed synthesis of marine-sourced indole derivatives: suppressing gram-negative bacteria biofilm and virulence.	Golberg K, Elouarzaki K, Kagan BE, Shagan M, Shemesh N, Kramarsky-Winter E, Ben-Zvi A, Nebenzahl YM, Marks RS, Kushmaro A.	BMC Biol	10.1186/s12915-025-02234-7	2025
Genetics	Macrogenomics Reveals Effects on Marine Microbial Communities during Oplegnathus punctatus Enclosure Farming.	Wang L, Lu X, Xing Z, Teng X, Wang S, Liu T, Zheng L, Wang X, Qu J.	Biology (Basel)	10.3390/biology13080618	2024
Genetics	Genetic Diversity of Clinical Bordetella Pertussis ST2 Strains in comparison with Vaccine Reference Strains of India.	Sharma NC, Anandan S, Devanga Ragupathi NK, Muthuirulandi Sethuvel DP, Vasudevan K, Kumar D, Gupta SK, Sangal L, Veeraraghavan B.	J Genomics	10.7150/jgen.58823	2021
Phylogeny	Evolutionary Divergence of the Wsp Signal Transduction Systems in Beta- and Gammaproteobacteria.	Kessler C, Mhatre E, Cooper V, Kim W.	Appl Environ Microbiol	10.1128/aem.01306-21	2021
	Structure and Function of ArnD. A Deformylase Essential for Lipid A Modification with 4-Amino-4-deoxy-l-arabinose and Polymyxin Resistance.	Munoz-Escudero D, Breazeale SD, Lee M, Guan Z, Raetz CRH, Sousa MC.	Biochemistry	10.1021/acs.biochem.3c00293	2023
	RNA-seq analysis in simulated microgravity unveils down-regulation of the beta-rhizobial siderophore phymabactin.	Golaz D, Papenfuhs CK, Belles-Sancho P, Eberl L, Egli M, Pessi G.	NPJ Microgravity	10.1038/s41526-024-00391-7	2024
	Base editing in human cells with monomeric DddA-TALE fusion deaminases.	Mok YG, Lee JM, Chung E, Lee J, Lim K, Cho SI, Kim JS.	Nat Commun	10.1038/s41467-022-31745-y	2022
	Genetic architecture constrains exploitation of siderophore cooperation in the bacterium Burkholderia cenocepacia.	Sathe S, Mathew A, Agnoli K, Eberl L, Kummerli R.	Evol Lett	10.1002/evl3.144	2019
	Intracellular survival of Burkholderia cepacia complex in phagocytic cells.	Valvano MA.	Can J Microbiol	10.1139/cjm-2015-0316	2015
	A Burkholderia cenocepacia gene encoding a non-functional tyrosine phosphatase is required for the delayed maturation of the bacteria-containing vacuoles in macrophages.	Andrade A, Andrade A, Valvano MA.	Microbiology (Reading)	10.1099/mic.0.077206-0	2014
	Expression and localisation of MUC1 modified with sialylated core-2 O-glycans in mucoepidermoid carcinoma.	Sugiura T, Hashimoto K, Kikuta K, Anazawa U, Nomura T, Kameyama A.	Sci Rep	10.1038/s41598-023-32597-2	2023
	Variation of Burkholderia cenocepacia cell wall morphology and mechanical properties during cystic fibrosis lung infection, assessed by atomic force microscopy.	Hassan AA, Vitorino MV, Robalo T, Rodrigues MS, Sa-Correia I.	Sci Rep	10.1038/s41598-019-52604-9	2019
	Effect of malate on the activity of ciprofloxacin against Pseudomonas aeruginosa in different in vivo and in vivo-like infection models.	Bao X, Goeteyn E, Crabbe A, Coenye T.	Antimicrob Agents Chemother	10.1128/aac.00682-23	2023
Metabolism	Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo.	Estfanous S, Krause K, Anne MNK, Eltobgy M, Caution K, Abu Khweek A, Hamilton K, Badr A, Daily K, Carafice C, Baetzhold D, Zhang X, Li T, Wen H, Gavrilin MA, Haffez H, Soror S, Amer AO.	Sci Rep	10.1038/s41598-020-79201-5	2021
	Chemical, Metabolic, and Cellular Characterization of a FtsZ Inhibitor Effective Against Burkholderia cenocepacia.	Chiarelli LR, Scoffone VC, Trespidi G, Barbieri G, Riabova O, Monakhova N, Porta A, Manina G, Riccardi G, Makarov V, Buroni S.	Front Microbiol	10.3389/fmicb.2020.00562	2020
	Hinokitiol potentiates antimicrobial activity of bismuth drugs: a combination therapy for overcoming antimicrobial resistance.	Ip TK, Wang Y, Wang S, Pu K, Wang R, Han B, Gao P, Xie Y, Kao RY, Ho PL, Li H, Sun H.	RSC Med Chem	10.1039/d4md00860j	2025
Pathogenicity	Normoferremia in Patients with Acute Bacterial Infections-A Hitherto Unexplored Field of the Dichotomy between CRP and Ferritin Expression in Patients with Hyper Inflammation and Failure to Increase Ferritin.	Levinson T, Feigin E, Berliner S, Shenhar-Tsarfaty S, Shapira I, Rogowski O, Zeltzer D, Goldiner I, Shtark M, Katz Shalhav M, Wasserman A.	Int J Mol Sci	10.3390/ijms241411350	2023
	Evaluation of Antimicrobial Susceptibility Testing Methods for Burkholderia cenocepacia and Burkholderia multivorans Isolates from Cystic Fibrosis Patients.	Huse HK, Lee MJ, Wootton M, Sharp SE, Traczewski M, LiPuma JJ, Jorth P.	J Clin Microbiol	10.1128/jcm.01447-21	2021
	Interferon-gamma-activated macrophages infected with Burkholderia cenocepacia process and present bacterial antigens to T-cells by class I and II major histocompatibility complex molecules.	Rosales-Reyes R, Garza-Villafuerte P, Vences-Vences D, Aubert DF, Aca-Teutle R, Ortiz-Navarrete VF, Bonifaz LC, Carrero-Sanchez JC, Olivos-Garcia A, Valvano MA, Santos-Preciado JI.	Emerg Microbes Infect	10.1080/22221751.2020.1818632	2020
	In vitro volatile organic compound profiling using GC×GC-TOFMS to differentiate bacteria associated with lung infections: a proof-of-concept study.	Nizio KD, Perrault KA, Troobnikoff AN, Ueland M, Shoma S, Iredell JR, Middleton PG, Forbes SL.	J Breath Res	10.1088/1752-7155/10/2/026008	2016
Metabolism	Exploring the Organic Acid Secretion Pathway and Potassium Solubilization Ability of Pantoea vagans ZHS-1 for Enhanced Rice Growth.	Tian S, Xu Y, Zhong Y, Qiao Y, Wang D, Wu L, Yang X, Yang M, Wu Z.	Plants (Basel)	10.3390/plants13141945	2024
	Lung transplantation in children.	Ehrsam JP, Meier Adamenko O, Pannu M, Markus Schob O, Inci I.	Turk Gogus Kalp Damar Cerrahisi Derg	10.5606/tgkdc.dergisi.2024.25806	2024
Enzymology	An outbreak of Burkholderia cenocepacia associated with contaminated chlorhexidine solutions prepared in the hospital.	Lee S, Han SW, Kim G, Song DY, Lee JC, Kwon KT.	Am J Infect Control	10.1016/j.ajic.2013.01.024	2013
Pathogenicity	Disruption of Quorum Sensing and Virulence in Burkholderia cenocepacia by a Structural Analogue of the cis-2-Dodecenoic Acid Signal.	Cui C, Song S, Yang C, Sun X, Huang Y, Li K, Zhao S, Zhang Y, Deng Y.	Appl Environ Microbiol	10.1128/aem.00105-19	2019
Pathogenicity	Pseudomonas aeruginosa displays an altered phenotype in vitro when grown in the presence of mannitol.	Moore JE, Rendall JC, Downey DG.	Br J Biomed Sci	10.1080/09674845.2015.11666807	2015
	In Vitro Antioxidant and In Silico Evaluation of the Anti-beta-Lactamase Potential of the Extracts of Cylindrospermum alatosporum NR125682 and Loriellopsis cavenicola NR117881.	Ikhane AO, Sithole SZ, Cele ND, Osunsanmi FO, Mosa RA, Opoku AR.	Antioxidants (Basel)	10.3390/antiox13050608	2024
	Comparative evaluation of antimicrobial peptides: effect on formation, metabolic activity and viability of Klebsiella pneumoniae biofilms.	Hanstein S, Grochow T, Motzing M, Fietz SA, Hoffmann R, Baums CG, Kahl S.	Front Microbiol	10.3389/fmicb.2025.1548362	2025
Phylogeny	Accurate identification of members of the Burkholderia cepacia complex in cystic fibrosis sputum.	Martinucci M, Roscetto E, Iula VD, Votsi A, Catania MR, De Gregorio E.	Lett Appl Microbiol	10.1111/lam.12537	2016
	Burkholderia cenocepacia transcriptome during the early contacts with giant plasma membrane vesicles derived from live bronchial epithelial cells.	Pimenta AI, Bernardes N, Alves MM, Mil-Homens D, Fialho AM.	Sci Rep	10.1038/s41598-021-85222-5	2021
	Activity of biogenic silver nanoparticles in planktonic and biofilm-associated Corynebacterium pseudotuberculosis.	Santos LM, Rodrigues DM, Alves BVB, Kalil MA, Azevedo V, Barh D, Meyer R, Duran N, Tasic L, Portela RW.	PeerJ	10.7717/peerj.16751	2024
	Wild mushrooms as potential reservoirs of plant pathogenic bacteria: a case study on Burkholderia gladioli.	Hamidizade M, Taghavi SM, Soleimani A, Bouazar M, Abachi H, Portier P, Osdaghi E.	Microbiol Spectr	10.1128/spectrum.03395-23	2024
	The association between cystic fibrosis-related diabetes and periodontitis in adults: A pilot cross-sectional study.	Alkhateeb AA, Mancl LA, Ramos KJ, Rothen ML, Kotsakis GA, Trence DL, Chi DL.	PLoS One	10.1371/journal.pone.0305975	2024
	Mutation Rate and Effective Population Size of the Model Cooperative Bacterium Myxococcus xanthus.	Wielgoss S, Van Dyken JD, Velicer GJ.	Genome Biol Evol	10.1093/gbe/evae066	2024
Metabolism	Oxidative stress in cystic fibrosis patients with Burkholderia cenocepacia airway colonization: relation of 8-isoprostane concentration in exhaled breath condensate to lung function decline.	Fila L, Grandcourtova A, Chladek J, Musil J.	Folia Microbiol (Praha)	10.1007/s12223-013-0285-z	2014
	The insight into the biology of five homologous lectins produced by the entomopathogenic bacterium and nematode symbiont Photorhabdus laumondii.	Paulenova E, Dobes P, Melicher F, Houser J, Faltinek L, Hyrsl P, Wimmerova M.	Glycobiology	10.1093/glycob/cwaf033	2025
Metabolism	Single-molecule atomic force microscopy unravels the binding mechanism of a Burkholderia cenocepacia trimeric autotransporter adhesin.	El-Kirat-Chatel S, Mil-Homens D, Beaussart A, Fialho AM, Dufrene YF.	Mol Microbiol	10.1111/mmi.12301	2013
Metabolism	Deciphering the role of Burkholderia cenocepacia membrane proteins in antimicrobial properties of chitosan.	Ibrahim M, Tao Z, Hussain A, Chunlan Y, Ilyas M, Waheed A, Yuan F, Li B, Xie GL.	Arch Microbiol	10.1007/s00203-013-0936-0	2014
	Regulation of the physiology and virulence of Ralstonia solanacearum by the second messenger 2',3'-cyclic guanosine monophosphate.	Li X, Yin W, Lin JD, Zhang Y, Guo Q, Wang G, Chen X, Cui B, Wang M, Chen M, Li P, He YW, Qian W, Luo H, Zhang LH, Liu XW, Song S, Deng Y.	Nat Commun	10.1038/s41467-023-43461-2	2023
Lipids	An evolutionary conserved detoxification system for membrane lipid-derived peroxyl radicals in Gram-negative bacteria.	Naguib M, Feldman N, Zarodkiewicz P, Shropshire H, Biamis C, El-Halfawy OM, McCain J, Dezanet C, Decout JL, Chen Y, Cosa G, Valvano MA.	PLoS Biol	10.1371/journal.pbio.3001610	2022
	Isophthalate:coenzyme A ligase initiates anaerobic degradation of xenobiotic isophthalate.	Junghare M, Frey J, Naji KM, Spiteller D, Vaaje-Kolstad G, Schink B.	BMC Microbiol	10.1186/s12866-022-02630-x	2022
	VimR is a conserved master transcription regulator controlling virulence and metabolism in Pseudomonas.	Chen F, Sun Y, Huang J, Li T, Lu B, He Z, Li J, Wang T, Hu H, Deng X.	Nucleic Acids Res	10.1093/nar/gkaf493	2025
	Soft rot pathogen Dickeya dadantii 3937 produces tailocins resembling the tails of Peduovirus P2.	Borowicz M, Krzyzanowska DM, Narajczyk M, Sobolewska M, Rajewska M, Czaplewska P, Wegrzyn K, Czajkowski R.	Front Microbiol	10.3389/fmicb.2023.1307349	2023
	ArgR regulates motility and virulence through positive control of flagellar genes and inhibition of diguanylate cyclase expression in Aeromonas veronii.	Wang Z, Tang Y, Li H, Li J, Chi X, Ma X, Liu Z.	Commun Biol	10.1038/s42003-024-07392-y	2024
	Biological control of fruit-rot of jackfruit by rhizobacteria and food grade lactic acid bacteria	Ghosh R, Barman S, Mukhopadhyay A, Mandal NC.	Biol Control	10.1016/j.biocontrol.2014.12.020	2015
	Quorum sensing systems influence Burkholderia cenocepacia virulence.	Subramoni S, Sokol PA.	Future Microbiol	10.2217/fmb.12.118	2012
	Compact zinc finger architecture utilizing toxin-derived cytidine deaminases for highly efficient base editing in human cells.	Fauser F, Kadam BN, Arangundy-Franklin S, Davis JE, Vaidya V, Schmidt NJ, Lew G, Xia DF, Mureli R, Ng C, Zhou Y, Scarlott NA, Eshleman J, Bendana YR, Shivak DA, Reik A, Li P, Davis GD, Miller JC.	Nat Commun	10.1038/s41467-024-45100-w	2024
	Candida albicans Ubiquitin and Heat Shock Factor-Type Transcriptional Factors Are Involved in 2-Dodecenoic Acid-Mediated Inhibition of Hyphal Growth.	Yang D, Hu Y, Yin Z, Gao Q, Zhang Y, Chan FY, Zeng G, Weng L, Wang L, Wang Y.	Microorganisms	10.3390/microorganisms8010075	2020
Metabolism	Defective immunometabolism pathways in cystic fibrosis macrophages.	Hamilton K, Krause K, Badr A, Daily K, Estfanous S, Eltobgy M, Khweek AA, Anne MNK, Carafice C, Baetzhold D, Tonniges JR, Zhang X, Gavrilin MA, Parinandi NL, Amer AO.	J Cyst Fibros	10.1016/j.jcf.2020.10.006	2021
	Antibiotic Cycling Reverts Extensive Drug Resistance in Burkholderia multivorans.	Kavanaugh LG, Harrison SK, Flanagan JN, Steck TR.	Antimicrob Agents Chemother	10.1128/aac.00611-21	2021
Metabolism	Free Energy Analysis of a Conformational Change of Heme ABC Transporter BhuUV-T.	Tamura K, Sugita Y.	J Phys Chem Lett	10.1021/acs.jpclett.0c00547	2020
	The phytopathogen Xanthomonas campestris senses and effluxes salicylic acid via a sensor HepR and an RND family efflux pump to promote virulence in host plants.	Song K, Li R, Cui Y, Chen B, Zhou L, Han W, Jiang BL, He YW.	mLife	10.1002/mlf2.12140	2024
Enzymology	Understanding xylose isomerase from Burkholderia cenocepacia: insights into structure and functionality for ethanol production.	Vieira IPV, Cordeiro GT, Gomes DEB, Melani RD, Vilela LF, Domont GB, Mesquita RD, Eleutherio ECA, Neves BC.	AMB Express	10.1186/s13568-019-0795-4	2019
	Value of T6SS Core Gene hcp in Acinetobacter baumannii Respiratory Tract Infection.	Hu YY, Chen S, Zhang YD, Lu QW, Wang F, Ren A, Liu CX.	Indian J Microbiol	10.1007/s12088-023-01083-8	2023
	Burkholderia cenocepacia Strain CEIB S5-1, a Rhizosphere-Inhabiting Bacterium with Potential in Bioremediation.	Martinez-Ocampo F, Lozano-Aguirre Beltran LF, Hernandez-Mendoza A, Rojas-Espinoza LE, Popoca-Ursino EC, Ortiz-Hernandez ML, Sanchez-Salinas E, Ramos Quintana F, Dantan-Gonzalez E.	Genome Announc	10.1128/genomea.00056-15	2015
	Role of two RpoN in Bradyrhizobium sp. strain DOA9 in symbiosis and free-living growth.	Wongdee J, Piromyou P, Songwattana P, Greetatorn T, Teaumroong N, Boonkerd N, Giraud E, Nouwen N, Tittabutr P.	Front Microbiol	10.3389/fmicb.2023.1131860	2023
	Developing mitochondrial base editors with diverse context compatibility and high fidelity via saturated spacer library.	Sun H, Wang Z, Shen L, Feng Y, Han L, Qian X, Meng R, Ji K, Liang D, Zhou F, Lou X, Zhang J, Shen B.	Nat Commun	10.1038/s41467-023-42359-3	2023
	Association of Tocilizumab and Invasive Aspergillosis in Critically Ill Patients with Severe COVID-19 Pneumonia and Acute Respiratory Distress Syndrome.	Wu KL, Chang CY, Sung HY, Hu TY, Kuo LK.	J Fungi (Basel)	10.3390/jof8040339	2022
	Investigating the Mechanism of Action of Diketopiperazines Inhibitors of the Burkholderia cenocepacia Quorum Sensing Synthase CepI: A Site-Directed Mutagenesis Study.	Buroni S, Scoffone VC, Fumagalli M, Makarov V, Cagnone M, Trespidi G, De Rossi E, Forneris F, Riccardi G, Chiarelli LR.	Front Pharmacol	10.3389/fphar.2018.00836	2018
Metabolism	Role of Burkholderia cenocepacia afcE and afcF genes in determining lipid-metabolism-associated phenotypes.	Subramoni S, Agnoli K, Eberl L, Lewenza S, Sokol PA.	Microbiology (Reading)	10.1099/mic.0.064683-0	2013
	Biochemical and structural characterization of two cif-like epoxide hydrolases from Burkholderia cenocepacia.	Taher NM, Hvorecny KL, Burke CM, Gilman MSA, Heussler GE, Adolf-Bryfogle J, Bahl CD, O'Toole GA, Madden DR.	Curr Res Struct Biol	10.1016/j.crstbi.2021.02.002	2021
Genetics	Genomic analyses of Burkholderia cenocepacia reveal multiple species with differential host-adaptation to plants and humans.	Wallner A, King E, Ngonkeu ELM, Moulin L, Bena G.	BMC Genomics	10.1186/s12864-019-6186-z	2019
	Antibiotherapy in Children with Cystic Fibrosis-An Extensive Review.	Ciuca IM, Dediu M, Popin D, Pop LL, Tamas LA, Pilut CN, Almajan Guta B, Popa ZL.	Children (Basel)	10.3390/children9081258	2022
	Comparison of single bacteria and a bacterial reference community in a test against coated surfaces of varying copper content.	Ly-Sauerbrey Y, Anton R, Kopruch L, Kramer CL, Boschert AL, Neidhofer C, Schwengers O, Zander D, Leuko S.	Front Microbiol	10.3389/fmicb.2025.1659828	2025
	Distinct Pathogenic Patterns of Burkholderia pseudomallei Isolates Selected from Caenorhabditis elegans and Dictyostelium discoideum Models.	Chen YL, Hsu DW, Hsueh PT, Chen JA, Shih PJ, Lee S, Lin HH, Chen YS.	Am J Trop Med Hyg	10.4269/ajtmh.19-0052	2019
Pathogenicity	Effects of Extended Storage of Chlorhexidine Gluconate and Benzalkonium Chloride Solutions on the Viability of Burkholderia cenocepacia.	Ahn Y, Kim JM, Lee YJ, LiPuma J, Hussong D, Marasa B, Cerniglia C.	J Microbiol Biotechnol	10.4014/jmb.1706.06034	2017
	Novel diagnostic PCR assay for Burkholderia cenocepacia epidemic strain ST32 and its utility in monitoring infection in cystic fibrosis patients.	Dedeckova K, Kalferstova L, Strnad H, Vavrova J, Drevinek P.	J Cyst Fibros	10.1016/j.jcf.2012.12.007	2013
	The genetic basis of cadmium resistance of Burkholderia cenocepacia.	Schwager S, Lumjiaktase P, Stockli M, Weisskopf L, Eberl L.	Environ Microbiol Rep	10.1111/j.1758-2229.2012.00372.x	2012
	Regulation of biofilm formation in Pseudomonas and Burkholderia species.	Fazli M, Almblad H, Rybtke ML, Givskov M, Eberl L, Tolker-Nielsen T.	Environ Microbiol	10.1111/1462-2920.12448	2014
Metabolism	A general protein O-glycosylation system within the Burkholderia cepacia complex is involved in motility and virulence.	Lithgow KV, Scott NE, Iwashkiw JA, Thomson EL, Foster LJ, Feldman MF, Dennis JJ, Dennis JJ.	Mol Microbiol	10.1111/mmi.12540	2014
Genetics	Natural Chromosome-Chromid Fusion across rRNA Operons in a Burkholderiaceae Bacterium.	Mori JF, Kanaly RA.	Microbiol Spectr	10.1128/spectrum.02225-21	2022
	Novel Ralstonia species from human infections: improved matrix-assisted laser desorption/ionization time-of-flight mass spectrometry-based identification and analysis of antimicrobial resistance patterns.	Steyaert S, Peeters C, Wieme AD, Muyldermans A, Vandoorslaer K, Spilker T, Wybo I, Pierard D, LiPuma JJ, Vandamme P.	Microbiol Spectr	10.1128/spectrum.04021-23	2024
	Contamination of hypertonic saline solutions in use by cystic fibrosis patients in Israel.	Peled O, Kalamaro V, Kerem E, Shoseyov D, Blau H, Efrati O, Block C.	J Cyst Fibros	10.1016/j.jcf.2014.01.001	2014
	Menadione as Antibiotic Adjuvant Against P. aeruginosa: Mechanism of Action, Efficacy and Safety.	Shehu K, Schneider M, Kraegeloh A.	Antibiotics (Basel)	10.3390/antibiotics14020163	2025
Metabolism	Phenylacetyl Coenzyme A, Not Phenylacetic Acid, Attenuates CepIR-Regulated Virulence in Burkholderia cenocepacia.	Lightly TJ, Frejuk KL, Groleau MC, Chiarelli LR, Ras C, Buroni S, Deziel E, Sorensen JL, Cardona ST.	Appl Environ Microbiol	10.1128/aem.01594-19	2019
	A yceI Gene Involves in the Adaptation of Ralstonia solanacearum to Methyl Gallate and Other Stresses.	Wang KH, Zheng DH, Yuan GQ, Lin W, Li QQ.	Microorganisms	10.3390/microorganisms9091982	2021
	Diversity and Phosphate Solubilization Efficiency of Phosphate Solubilizing Bacteria Isolated from Semi-Arid Agroecosystems of Eastern Kenya.	Kirui CK, Njeru EM, Runo S.	Microbiol Insights	10.1177/11786361221088991	2022
	Pseudomonas virulence factor controls expression of virulence genes in Pseudomonas entomophila.	Acken KA, Li B.	PLoS One	10.1371/journal.pone.0284907	2023
	Lung transplantation for late-onset non-infectious chronic pulmonary complications of allogenic hematopoietic stem cell transplant.	Riddell P, Vasudevan-Nampoothiri R, Ma J, Singer LG, Lipton JH, Juvet SC.	Respir Res	10.1186/s12931-021-01699-8	2021
	A Bacterial Isolate Capable of Quenching Both Diffusible Signal Factor- and N-Acylhomoserine Lactone-Family Quorum Sensing Signals Shows Much Enhanced Biocontrol Potencies.	Wang H, Lin Q, Dong L, Wu W, Liang Z, Dong Z, Ye H, Liao L, Zhang LH.	J Agric Food Chem	10.1021/acs.jafc.2c01299	2022
Phylogeny	Incidence of Burkholderia contaminans at a cystic fibrosis centre with an unusually high representation of Burkholderia cepacia during 15 years of epidemiological surveillance.	Coutinho CP, Barreto C, Pereira L, Lito L, Melo Cristino J, Sa-Correia I.	J Med Microbiol	10.1099/jmm.0.000094	2015
Metabolism	Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome.	Xu H, Yang J, Gao W, Li L, Li P, Zhang L, Gong YN, Peng X, Xi JJ, Chen S, Wang F, Shao F.	Nature	10.1038/nature13449	2014
Metabolism	Functional expression of Burkholderia cenocepacia xylose isomerase in yeast increases ethanol production from a glucose-xylose blend.	de Figueiredo Vilela L, de Mello VM, Reis VC, Bon EP, Goncalves Torres FA, Neves BC, Eleutherio EC.	Bioresour Technol	10.1016/j.biortech.2012.10.014	2013
	A Bird's-Eye View of the Pathophysiologic Role of the Human Urobiota in Health and Disease: Can We Modulate It?	Jirillo E, Palmirotta R, Colella M, Santacroce L.	Pathophysiology	10.3390/pathophysiology31010005	2024
	Constructions of quorum sensing signaling network for activated sludge microbial community.	Jin Y, Chen W, Hu J, Wang J, Ren H.	ISME Commun	10.1093/ismeco/ycae018	2024
	Human Milk Oligosaccharides Exhibit Biofilm Eradication Activity Against Matured Biofilms Formed by Different Pathogen Species.	Jarzynka S, Spott R, Tchatchiashvili T, Ueberschaar N, Martinet MG, Strom K, Kryczka T, Wesolowska A, Pletz MW, Oledzka G, Makarewicz O.	Front Microbiol	10.3389/fmicb.2021.794441	2021
Metabolism	Investigation of Burkholderia cepacia Complex Methylomes via Single-Molecule, Real-Time Sequencing and Mutant Analysis.	Mannweiler O, Pinto-Carbo M, Lardi M, Agnoli K, Eberl L.	J Bacteriol	10.1128/jb.00683-20	2021
	A hypervirulent Acinetobacter baumannii strain has robust anti-phagocytosis ability.	Li Y, Jv M, Zhuang Y, Zhao X, Hu X.	BMC Microbiol	10.1186/s12866-024-03264-x	2024
Metabolism	The Burkholderia cenocepacia sensor kinase hybrid AtsR is a global regulator modulating quorum-sensing signalling.	Aubert DF, O'Grady EP, Hamad MA, Sokol PA, Valvano MA.	Environ Microbiol	10.1111/j.1462-2920.2012.02828.x	2013
	Role of RND Efflux Pumps in Drug Resistance of Cystic Fibrosis Pathogens.	Scoffone VC, Trespidi G, Barbieri G, Irudal S, Perrin E, Buroni S.	Antibiotics (Basel)	10.3390/antibiotics10070863	2021
Phylogeny	Burkholderia species in human infections in Mexico: Identification of B. cepacia, B. contaminans, B. multivorans, B. vietnamiensis,B. pseudomallei and a new Burkholderia species.	Meza-Radilla G, Larios-Serrato V, Hernandez-Castro R, Ibarra JA, Estrada-de Los Santos P.	PLoS Negl Trop Dis	10.1371/journal.pntd.0009541	2021
Metabolism	Pore-forming pyocin S5 utilizes the FptA ferripyochelin receptor to kill Pseudomonas aeruginosa.	Elfarash A, Dingemans J, Ye L, Hassan AA, Craggs M, Reimmann C, Thomas MS, Cornelis P.	Microbiology (Reading)	10.1099/mic.0.070672-0	2014
	Alteration of lipopolysaccharide O antigen leads to avirulence of gut-colonizing Serratia marcescens.	Lee J, Kim JU, Lee BL, Kim JK.	Front Microbiol	10.3389/fmicb.2023.1278917	2023
	Burkholderia cenocepacia lectin A binding to heptoses from the bacterial lipopolysaccharide.	Marchetti R, Malinovska L, Lameignere E, Adamova L, de Castro C, Cioci G, Stanetty C, Kosma P, Molinaro A, Wimmerova M, Imberty A, Silipo A.	Glycobiology	10.1093/glycob/cws105	2012
	Combined Analysis of Multiple Glycan-Array Datasets: New Explorations of Protein-Glycan Interactions.	Klamer Z, Haab B.	Anal Chem	10.1021/acs.analchem.1c01739	2021
	Clinafloxacin for Treatment of Burkholderia cenocepacia Infection in a Cystic Fibrosis Patient.	Balwan A, Nicolau DP, Wungwattana M, Zuckerman JB, Waters V.	Antimicrob Agents Chemother	10.1128/aac.masthead.60-1	2016
	Candida-bacterial cross-kingdom interactions.	Eichelberger KR, Paul S, Peters BM, Cassat JE.	Trends Microbiol	10.1016/j.tim.2023.08.003	2023
Genetics	Geography, niches, and transportation influence bovine respiratory microbiome and health.	Chai J, Liu X, Usdrowski H, Deng F, Li Y, Zhao J.	Front Cell Infect Microbiol	10.3389/fcimb.2022.961644	2022
Metabolism	Influence of ligand presentation density on the molecular recognition of mannose-functionalised glyconanoparticles by bacterial lectin BC2L-A.	Reynolds M, Marradi M, Imberty A, Penades S, Perez S.	Glycoconj J	10.1007/s10719-013-9478-6	2013
	A Burkholderia thailandensis DedA Family Membrane Protein Is Required for Proton Motive Force Dependent Lipid A Modification.	Panta PR, Doerrler WT.	Front Microbiol	10.3389/fmicb.2020.618389	2020
Metabolism	[Mutants of Burkholderia cenocepacia with a change in synthesis of N-acyl-homoserine lactones--signal molecules of Quorum Sensing regulation].	Veselova MA, Lipasova VA, Zaitseva IuV, Koksharova OA, Chernukha MIu, Romanova IuM, Khmel' IA.	Genetika	10.1134/s1022795412050213	2012
	DNA Methylation Epigenetically Regulates Gene Expression in Burkholderia cenocepacia and Controls Biofilm Formation, Cell Aggregation, and Motility.	Vandenbussche I, Sass A, Pinto-Carbo M, Mannweiler O, Eberl L, Coenye T.	mSphere	10.1128/msphere.00455-20	2020
	Burkholderia Bacteria Produce Multiple Potentially Novel Molecules that Inhibit Carbapenem-Resistant Gram-Negative Bacterial Pathogens.	Depoorter E, De Canck E, Coenye T, Vandamme P.	Antibiotics (Basel)	10.3390/antibiotics10020147	2021
Enzymology	Burkholderia species infections in patients with cystic fibrosis in British Columbia, Canada. 30 years' experience.	Zlosnik JE, Zhou G, Brant R, Henry DA, Hird TJ, Mahenthiralingam E, Chilvers MA, Wilcox P, Speert DP.	Ann Am Thorac Soc	10.1513/annalsats.201408-395oc	2015
Genetics	Burkholderia cenocepacia Prophages-Prevalence, Chromosome Location and Major Genes Involved.	Roszniowski B, McClean S, Drulis-Kawa Z.	Viruses	10.3390/v10060297	2018
Metabolism	The suhB gene of Burkholderia cenocepacia is required for protein secretion, biofilm formation, motility and polymyxin B resistance.	Rosales-Reyes R, Saldias MS, Aubert DF, El-Halfawy OM, Valvano MA.	Microbiology (Reading)	10.1099/mic.0.060988-0	2012
Pathogenicity	Extracellular vesicles secreted by primary human bronchial epithelial cells reduce Pseudomonas aeruginosa burden and inflammation in cystic fibrosis mouse lung.	Sarkar S, Barnaby R, Nymon AB, Taatjes DJ, Kelley TJ, Stanton BA.	Am J Physiol Lung Cell Mol Physiol	10.1152/ajplung.00253.2023	2024
	Bacterial diversity significantly reduces toward the late stages among filarial lymphedema patients in the Ahanta West District of Ghana: A cross-sectional study.	Asiedu SO, Kini P, Aglomasa BC, Amewu EKA, Asiedu E, Wireko S, Boahen KG, Berbudi A, Sylverken AA, Kwarteng A.	Health Sci Rep	10.1002/hsr2.724	2022
	In Vitro Antibiofilm Activity of Resveratrol against Aeromonas hydrophila.	Qin T, Chen K, Xi B, Pan L, Xie J, Lu L, Liu K.	Antibiotics (Basel)	10.3390/antibiotics12040686	2023
	Targets for the diagnosis of Acanthamoeba eye infections include four cyst wall proteins and the mannose-binding domain of the trophozoite mannose-binding protein.	Kanakapura Sundararaj B, Goyal M, Samuelson J.	mSphere	10.1128/msphere.00948-24	2025
	CircCDC42-encoded CDC42-165aa regulates macrophage pyroptosis in Klebsiella pneumoniae infection through Pyrin inflammasome activation.	Xu N, Jiang J, Jiang F, Dong G, Meng L, Wang M, Chen J, Li C, Shi Y, He S, Li R.	Nat Commun	10.1038/s41467-024-50154-x	2024
	The Fem cell-surface signaling system is regulated by ExsA in Pseudomonas aeruginosa and affects pathogenicity.	Li Y, Bhagirath A, Badr S, Zhang P, Chen L, Dadashi M, Surette MG, Duan K.	iScience	10.1016/j.isci.2024.111629	2025
	Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol.	Dorrington MG, Bradfield CJ, Lack JB, Lin B, Liang JJ, Starr T, Ernst O, Gross JL, Sun J, Miller AH, Steele-Mortimer O, Fraser IDC.	PLoS Pathog	10.1371/journal.ppat.1009395	2021
	Identifying Novel Therapeutics for the Resistant Mutant "F533L" in PBP3 of Pseudomonas aeruginosa Using ML Techniques.	Joshi T, Vijayakumar S, Ghosh S, Mathpal S, Ramaiah S, Anbarasu A.	ACS Omega	10.1021/acsomega.4c00929	2024
	Roles of the Crp/Fnr Family Regulator ArcR in the Hemolysis and Biofilm of Staphylococcus aureus.	Fu T, Fan Z, Li Y, Li Z, Zhao H, Feng Y, Xue G, Cui J, Yan C, Gan L, Feng J, Yuan J, You F.	Microorganisms	10.3390/microorganisms11071656	2023
Pathogenicity	The antibacterial properties of docosahexaenoic omega-3 fatty acid against the cystic fibrosis multiresistant pathogen Burkholderia cenocepacia.	Mil-Homens D, Bernardes N, Fialho AM.	FEMS Microbiol Lett	10.1111/j.1574-6968.2011.02476.x	2012
	Screening microorganisms for insulin binding reveals binding by Burkholderia multivorans and Burkholderia cenocepacia and novel attachment of insulin to Aeromonas salmonicida via the A-layer.	Nisr RB, Moody AJ, Gilpin ML.	FEMS Microbiol Lett	10.1111/j.1574-6968.2011.02484.x	2012
	Negative frequency-dependent selection maintains coexisting genotypes during fluctuating selection.	Turner CB, Buskirk SW, Harris KB, Cooper VS.	Mol Ecol	10.1111/mec.15307	2020
	Metabolites limiting predator growth wane with prey biodiversity.	Li G, Liu T, Xie W, Liu Z, Li H, Whalen JK, Jousset A, Wei Z.	Proc Natl Acad Sci U S A	10.1073/pnas.2410210121	2024
	BysR, a LysR-Type Pleiotropic Regulator, Controls Production of Occidiofungin by Activating the LuxR-Type Transcriptional Regulator AmbR1 in Burkholderia sp. Strain JP2-270.	Wu L, Tang L, He Y, Han C, Wang L, Zhang Y, E Z.	Microbiol Spectr	10.1128/spectrum.02684-22	2023
	High-Throughput Tn-Seq Screens Identify Both Known and Novel Pseudomonas putida KT2440 Genes Involved in Metal Tolerance.	Royet K, Kergoat L, Lutz S, Oriol C, Parisot N, Schori C, Ahrens CH, Rodrigue A, Gueguen E.	Environ Microbiol	10.1111/1462-2920.70095	2025
	Antibiofilm approaches as a new paradigm for treating infections.	Reffuveille F, Dghoughi Y, Colin M, Torres MDT, de la Fuente-Nunez C.	Prog Biomed Eng (Bristol)	10.1088/2516-1091/ad1cd6	2024
Metabolism	Burkholderia cenocepacia disrupts host cell actin cytoskeleton by inactivating Rac and Cdc42.	Flannagan RS, Jaumouille V, Huynh KK, Plumb JD, Downey GP, Valvano MA, Grinstein S.	Cell Microbiol	10.1111/j.1462-5822.2011.01715.x	2012
	Bacteria that inhibit quorum sensing decrease biofilm formation and virulence in Pseudomonas aeruginosa PAO1.	Christiaen SE, Matthijs N, Zhang XH, Nelis HJ, Bossier P, Coenye T.	Pathog Dis	10.1111/2049-632x.12124	2014
	Progress in structural and functional study of the bacterial phenylacetic acid catabolic pathway, its role in pathogenicity and antibiotic resistance.	Jiao M, He W, Ouyang Z, Shi Q, Wen Y.	Front Microbiol	10.3389/fmicb.2022.964019	2022
	In Vitro Activities of beta-Lactam-beta-Lactamase Inhibitor Antimicrobial Agents against Cystic Fibrosis Respiratory Pathogens.	Caverly LJ, Spilker T, Kalikin LM, Stillwell T, Young C, Huang DB, LiPuma JJ.	Antimicrob Agents Chemother	10.1128/aac.01595-19	2019
	Unveiling the wonders of bacteria-derived extracellular vesicles: From fundamental functions to beneficial applications.	Rima M, Dakramanji M, El Hayek E, El Khoury T, Fajloun Z, Rima M.	Heliyon	10.1016/j.heliyon.2025.e42509	2025
Pathogenicity	Synthesis and evaluation of the quorum sensing inhibitory effect of substituted triazolyldihydrofuranones.	Brackman G, Risseeuw M, Celen S, Cos P, Maes L, Nelis HJ, Van Calenbergh S, Coenye T.	Bioorg Med Chem	10.1016/j.bmc.2012.06.009	2012
	Macrophages as drivers of an opportunistic infection.	Vergunst AC, Carranza NL, Zhang L, Gomes MC, Tasrini Y, Meijer AH, O'Callaghan D.	Microb Cell	10.15698/mic2017.10.595	2017
	Uncovering nitroxoline activity spectrum, mode of action and resistance across Gram-negative bacteria.	Cacace E, Tietgen M, Steinhauer M, Mateus A, Schultze TG, Eckermann M, Galardini M, Varik V, Koumoutsi A, Parzeller JJ, Corona F, Orakov A, Knopp M, Brauer-Nikonow A, Bork P, Romao CV, Zimmermann M, Cloetens P, Savitski MM, Typas A, Gottig S.	Nat Commun	10.1038/s41467-025-58730-5	2025
	The type VI secretion system of the emerging pathogen Stenotrophomonas maltophilia complex has antibacterial properties.	Crisan CV, Van Tyne D, Goldberg JB.	mSphere	10.1128/msphere.00584-23	2023
Metabolism	The Type VI secretion system of Burkholderia cenocepacia affects multiple Rho family GTPases disrupting the actin cytoskeleton and the assembly of NADPH oxidase complex in macrophages.	Rosales-Reyes R, Skeldon AM, Aubert DF, Valvano MA.	Cell Microbiol	10.1111/j.1462-5822.2011.01716.x	2012
Metabolism	Burkholderia cenocepacia integrates cis-2-dodecenoic acid and cyclic dimeric guanosine monophosphate signals to control virulence.	Yang C, Cui C, Ye Q, Kan J, Fu S, Song S, Huang Y, He F, Zhang LH, Jia Y, Gao YG, Harwood CS, Deng Y.	Proc Natl Acad Sci U S A	10.1073/pnas.1709048114	2017
	Vitamin E as promising adjunct treatment option in the combat of infectious diseases caused by bacterial including multi-drug resistant pathogens - Results from a comprehensive literature survey.	Hartmann MS, Mousavi S, Bereswill S, Heimesaat MM.	Eur J Microbiol Immunol (Bp)	10.1556/1886.2020.00020	2020
	In vitro and in vivo activity of cefiderocol against Achromobacter spp. and Burkholderia cepacia complex, including carbapenem-non-susceptible isolates.	Takemura M, Nakamura R, Ota M, Nakai R, Sahm DF, Hackel MA, Yamano Y.	Antimicrob Agents Chemother	10.1128/aac.00346-23	2023
	Use of 3-hydroxy fatty acid concentrations in a murine air pouch infection model as a surrogate marker for LPS activity: a feasibility study using environmental Burkholderia cenocepacia isolates.	Chen YS, Lin HH, Liu PJ, Tsai HY, Hsueh PT, Liu HY, Chen YL.	J Microbiol Methods	10.1016/j.mimet.2011.10.004	2011
	Insertion sequence evolutionary patterns highlight convergent genetic inactivations and recent genomic island acquisitions among epidemic Burkholderia cenocepacia.	Graindorge A, Menard A, Monnez C, Cournoyer B.	J Med Microbiol	10.1099/jmm.0.036822-0	2012
	Molecular approaches to pathogenesis study of Burkholderia cenocepacia, an important cystic fibrosis opportunistic bacterium.	Bazzini S, Udine C, Riccardi G.	Appl Microbiol Biotechnol	10.1007/s00253-011-3616-5	2011
	A response regulator controls Acinetobacter baumannii virulence by acting as an indole receptor.	Cui B, Guo Q, Li X, Song S, Wang M, Wang G, Yan A, Zhou J, Deng Y.	PNAS Nexus	10.1093/pnasnexus/pgad274	2023
	Outcomes of intraoperative extracorporeal membrane oxygenation versus cardiopulmonary bypass for lung transplantation.	Machuca TN, Collaud S, Mercier O, Cheung M, Cunningham V, Kim SJ, Azad S, Singer L, Yasufuku K, de Perrot M, Pierre A, McRae K, Waddell TK, Keshavjee S, Cypel M.	J Thorac Cardiovasc Surg	10.1016/j.jtcvs.2014.11.039	2015
	High efficacy treatment of murine Pseudomonas aeruginosa catheter-associated urinary tract infections using the c-di-GMP modulating anti-biofilm compound Disperazol in combination with ciprofloxacin.	Hultqvist LD, Andersen JB, Nilsson CM, Jansen CU, Rybtke M, Jakobsen TH, Nielsen TE, Qvortrup K, Moser C, Graz M, Qvortrup K, Tolker-Nielsen T, Givskov M.	Antimicrob Agents Chemother	10.1128/aac.01481-23	2024
Pathogenicity	Lactoferrin decreases inflammatory response by cystic fibrosis bronchial cells invaded with Burkholderia cenocepacia iron-modulated biofilm.	Valenti P, Catizone A, Pantanella F, Frioni A, Natalizi T, Tendini M, Berlutti F.	Int J Immunopathol Pharmacol	10.1177/039463201102400423	2011
	The Use of Artificial Sputum Media to Enhance Investigation and Subsequent Treatment of Cystic Fibrosis Bacterial Infections.	Aiyer A, Manos J.	Microorganisms	10.3390/microorganisms10071269	2022
Enzymology	Burkholderia dolosa phenotypic variation during the decline in lung function of a cystic fibrosis patient during 5.5 years of chronic colonization.	Moreira AS, Coutinho CP, Azevedo P, Lito L, Melo-Cristino J, Sa-Correia I.	J Med Microbiol	10.1099/jmm.0.069849-0	2014
Genetics	Comparative Genome Analyses Provide Insight into the Antimicrobial Activity of Endophytic Burkholderia.	Jia J, Lu SE.	Microorganisms	10.3390/microorganisms12010100	2024
	Peptide modification results in the formation of a dimer with a 60-fold enhanced antimicrobial activity.	Thamri A, Letourneau M, Djoboulian A, Chatenet D, Deziel E, Castonguay A, Perreault J.	PLoS One	10.1371/journal.pone.0173783	2017
	Predicting bacterial interaction outcomes from monoculture growth and supernatant assays.	Schmitz DA, Wechsler T, Mignot I, Kummerli R.	ISME Commun	10.1093/ismeco/ycae045	2024
Phylogeny	Differences in strategies to combat osmotic stress in Burkholderia cenocepacia elucidated by NMR-based metabolic profiling.	Behrends V, Bundy JG, Williams HD.	Lett Appl Microbiol	10.1111/j.1472-765x.2011.03050.x	2011
Metabolism	Host Adaptation Predisposes Pseudomonas aeruginosa to Type VI Secretion System-Mediated Predation by the Burkholderia cepacia Complex.	Perault AI, Chandler CE, Rasko DA, Ernst RK, Wolfgang MC, Cotter PA.	Cell Host Microbe	10.1016/j.chom.2020.06.019	2020
	A Clinico-Microbiological Study of Prosthetic Joint Infections in an Indian Tertiary Care Hospital: Role of Universal 16S rRNA Gene Polymerase Chain Reaction and Sequencing in Diagnosis.	Sebastian S, Malhotra R, Sreenivas V, Kapil A, Chaudhry R, Dhawan B.	Indian J Orthop	10.4103/ortho.ijortho_551_18	2019
	The Isolation and Characterization of a Broad Host Range Bcep22-like Podovirus JC1.	Davis CM, Ruest MK, Cole JH, Dennis JJ.	Viruses	10.3390/v14050938	2022
	Inhibition of co-colonizing cystic fibrosis-associated pathogens by Pseudomonas aeruginosa and Burkholderia multivorans.	Costello A, Reen FJ, O'Gara F, Callaghan M, McClean S.	Microbiology (Reading)	10.1099/mic.0.074203-0	2014
Metabolism	Mechanistic insights of ABC importer HutCD involved in heme internalization by Vibrio cholerae.	Saha I, Chakraborty S, Agarwal S, Mukherjee P, Ghosh B, Dasgupta J.	Sci Rep	10.1038/s41598-022-11213-9	2022
	Optimization of resazurin-based viability staining for quantification of microbial biofilms.	Van den Driessche F, Rigole P, Brackman G, Coenye T.	J Microbiol Methods	10.1016/j.mimet.2013.12.011	2014
Genetics	A lung-specific mutational signature enables inference of viral and bacterial respiratory niche.	Ruis C, Peacock TP, Polo LM, Masone D, Alvarez MS, Hinrichs AS, Turakhia Y, Cheng Y, McBroome J, Corbett-Detig R, Parkhill J, Floto RA.	Microb Genom	10.1099/mgen.0.001018	2023
Metabolism	The CRP/FNR family protein Bcam1349 is a c-di-GMP effector that regulates biofilm formation in the respiratory pathogen Burkholderia cenocepacia.	Fazli M, O'Connell A, Nilsson M, Niehaus K, Dow JM, Givskov M, Ryan RP, Tolker-Nielsen T.	Mol Microbiol	10.1111/j.1365-2958.2011.07814.x	2011
	Diversity and Mechanisms of Action of Plant, Animal, and Human Antimicrobial Peptides.	Satchanska G, Davidova S, Gergova A.	Antibiotics (Basel)	10.3390/antibiotics13030202	2024
	Rit1-TBC1D10B signaling modulates FcgammaR-mediated phagosome formation in RAW264 macrophages.	Egami Y, Kawai K, Araki N.	Life Sci Alliance	10.26508/lsa.202402651	2024
	Ornithine Lipids in Burkholderia spp. Pathogenicity.	Cordoba-Castro LA, Salgado-Morales R, Torres M, Martinez-Aguilar L, Lozano L, Vences-Guzman MA, Guan Z, Dantan-Gonzalez E, Serrano M, Sohlenkamp C.	Front Mol Biosci	10.3389/fmolb.2020.610932	2020
	Burkholderia cenocepacia utilizes a type VI secretion system for bacterial competition.	Spiewak HL, Shastri S, Zhang L, Schwager S, Eberl L, Vergunst AC, Thomas MS.	Microbiologyopen	10.1002/mbo3.774	2019
	Respiratory infections in patients with cystic fibrosis undergoing lung transplantation.	Lobo LJ, Noone PG.	Lancet Respir Med	10.1016/s2213-2600(13)70162-0	2014
	Exploiting phage-antibiotic synergies to disrupt Pseudomonas aeruginosa PAO1 biofilms in the context of orthopedic infections.	De Soir S, Paree H, Kamarudin NHN, Wagemans J, Lavigne R, Braem A, Merabishvili M, De Vos D, Pirnay J-P, Van Bambeke F.	Microbiol Spectr	10.1128/spectrum.03219-23	2024
	Maternal gastrointestinal microbiome shapes gut microbial function and resistome of newborns in a cow-to-calf model.	Zhuang Y, Liu S, Gao D, Xu Y, Jiang W, Hou G, Li S, Zhao X, Chen T, Li S, Zhang S, Huang Y, Wang J, Xiao J, Li M, Wang W, Li S, Cao Z.	Microbiome	10.1186/s40168-024-01943-5	2024
Enzymology	Activation of MMP-9 by human lung epithelial cells in response to the cystic fibrosis-associated pathogen Burkholderia cenocepacia reduced wound healing in vitro.	Wright C, Pilkington R, Callaghan M, McClean S.	Am J Physiol Lung Cell Mol Physiol	10.1152/ajplung.00226.2010	2011
	Microbe Related Chemical Signalling and Its Application in Agriculture.	Abdul Hamid NW, Nadarajah K.	Int J Mol Sci	10.3390/ijms23168998	2022
Pathogenicity	A Broad-Host-Range Tailocin from Burkholderia cenocepacia.	Yao GW, Duarte I, Le TT, Carmody L, LiPuma JJ, Young R, Gonzalez CF.	Appl Environ Microbiol	10.1128/aem.03414-16	2017
	Draft Genome Sequences of Burkholderia cenocepacia ET12 Lineage Strains K56-2 and BC7.	Varga JJ, Losada L, Zelazny AM, Kim M, McCorrison J, Brinkac L, Sampaio EP, Greenberg DE, Singh I, Heiner C, Ashby M, Nierman WC, Holland SM, Goldberg JB.	Genome Announc	10.1128/genomea.00841-13	2013
Pathogenicity	Investigating the role of matrix components in protection of Burkholderia cepacia complex biofilms against tobramycin.	Messiaen AS, Nelis H, Coenye T.	J Cyst Fibros	10.1016/j.jcf.2013.07.004	2014
	A balancing act: investigations on the impact of altered signal sensitivity in bacterial quorum sensing.	Miranda SW, Greenberg EP.	J Bacteriol	10.1128/jb.00249-23	2023
Genetics	Development of TALE-adenine base editors in plants.	Zhang D, Boch J.	Plant Biotechnol J	10.1111/pbi.14246	2024
	Burkholderia cepacia complex Cervical Osteomyelitis in an Intravenous Drug User.	Li SK, Messer WB.	Case Rep Infect Dis	10.1155/2018/7638639	2018
Phylogeny	Potential of Novel Sequence Type of Burkholderia cenocepacia for Biological Control of Root Rot of Maize (Zea mays L.) Caused by Fusarium temperatum.	Tagele SB, Kim SW, Lee HG, Lee YS.	Int J Mol Sci	10.3390/ijms20051005	2019
Metabolism	The dioxygenase-encoding olsD gene from Burkholderia cenocepacia causes the hydroxylation of the amide-linked fatty acyl moiety of ornithine-containing membrane lipids.	Gonzalez-Silva N, Lopez-Lara IM, Reyes-Lamothe R, Taylor AM, Sumpton D, Thomas-Oates J, Geiger O.	Biochemistry	10.1021/bi200706v	2011
	Metabolic Network Models of the Gardnerella Pangenome Identify Key Interactions with the Vaginal Environment.	Dillard LR, Glass EM, Lewis AL, Thomas-White K, Papin JA.	mSystems	10.1128/msystems.00689-22	2023
Metabolism	Phenylalanine induces Burkholderia cenocepacia phenylacetic acid catabolism through degradation to phenylacetyl-CoA in synthetic cystic fibrosis sputum medium.	Yudistira H, McClarty L, Bloodworth RA, Hammond SA, Butcher H, Mark BL, Cardona ST.	Microb Pathog	10.1016/j.micpath.2011.04.002	2011
Genetics	Presence of a biofilm beneficiary alters the evolutionary trajectory of a biofilm former.	Sun X, Xu Z, Hu G, Xie J, Li Y, Tao L, Zhang N, Xun W, Miao Y, Zhang R, Shen Q, Kost C, Kovacs AT.	ISME J	10.1093/ismejo/wraf160	2025
	Comparative Genomics of Environmental and Clinical Burkholderia cenocepacia Strains Closely Related to the Highly Transmissible Epidemic ET12 Lineage.	Bodilis J, Denet E, Brothier E, Graindorge A, Favre-Bonte S, Nazaret S.	Front Microbiol	10.3389/fmicb.2018.00383	2018
	Simultaneous pectus excavatum correction and lung transplantation-A case series.	Rahimi N, Matilla JR, Lang G, Schwarz S, Nachbaur E, Benazzo A, Klepetko W, Jaksch P, Hoetzenecker K.	Am J Transplant	10.1111/ajt.16180	2021
Metabolism	Flagellin From Pseudomonas aeruginosa Modulates SARS-CoV-2 Infectivity in Cystic Fibrosis Airway Epithelial Cells by Increasing TMPRSS2 Expression.	Ruffin M, Bigot J, Calmel C, Mercier J, Givelet M, Oliva J, Pizzorno A, Rosa-Calatrava M, Corvol H, Balloy V, Terrier O, Guillot L.	Front Immunol	10.3389/fimmu.2021.714027	2021
	Microbiological diagnostic performance of metagenomic next-generation sequencing compared with conventional culture for patients with community-acquired pneumonia.	Lin T, Tu X, Zhao J, Huang L, Dai X, Chen X, Xu Y, Li W, Wang Y, Lou J, Wu S, Zhang H.	Front Cell Infect Microbiol	10.3389/fcimb.2023.1136588	2023
	Unraveling the Diverse Profile of N-Acyl Homoserine Lactone Signals and Their Role in the Regulation of Biofilm Formation in Porphyra haitanensis-Associated Pseudoalteromonas galatheae.	Aslam M, Pei P, Ye P, Li T, Liang H, Zhang Z, Ke X, Chen W, Du H.	Microorganisms	10.3390/microorganisms11092228	2023
	Localization and potential role of prostate microbiota.	Okada K, Takezawa K, Tsujimura G, Imanaka T, Kuribayashi S, Ueda N, Hatano K, Fukuhara S, Kiuchi H, Fujita K, Motooka D, Nakamura S, Koyama Y, Shimada S, Nonomura N.	Front Cell Infect Microbiol	10.3389/fcimb.2022.1048319	2022
Metabolism	An interbacterial DNA deaminase toxin directly mutagenizes surviving target populations.	de Moraes MH, Hsu F, Huang D, Bosch DE, Zeng J, Radey MC, Simon N, Ledvina HE, Frick JP, Wiggins PA, Peterson SB, Mougous JD.	Elife	10.7554/elife.62967	2021
	Management of Cepacia Syndrome With a Combination of Intravenous and Inhaled Antimicrobials in a Non-Cystic Fibrosis Pediatric Patient.	Branstetter JW, Yarbrough A, Poole C.	J Pediatr Pharmacol Ther	10.5863/1551-6776-25.8.730	2020
	Construction of Novel Yeast Strains from Candida tropicalis KBKTI 10.5.1 and Saccharomyces cerevisiae DBY1 to Improve the Performance of Ethanol Production Using Lignocellulosic Hydrolysate.	Jamaluddin, Riyanti EI, Mubarik NR, Listanto E.	Trop Life Sci Res	10.21315/tlsr2023.34.2.5	2023
Enzymology	Single amino acid substitution in homogentisate 1,2-dioxygenase is responsible for pigmentation in a subset of Burkholderia cepacia complex isolates.	Gonyar LA, Fankhauser SC, Goldberg JB.	Environ Microbiol Rep	10.1111/1758-2229.12217	2015
Pathogenicity	Activity of Tobramycin against Cystic Fibrosis Isolates of Burkholderia cepacia Complex Grown as Biofilms.	Kennedy S, Beaudoin T, Yau YC, Caraher E, Zlosnik JE, Speert DP, LiPuma JJ, Tullis E, Waters V.	Antimicrob Agents Chemother	10.1128/aac.02068-15	2016
Transcriptome	Transcriptome profiling of Paraburkholderia aromaticivorans AR20-38 during ferulic acid bioconversion.	Poyntner C, Ludwikowski TM, Wagner AO, Margesin R.	AMB Express	10.1186/s13568-022-01487-7	2022
	Pal Affects the Proliferation in Macrophages and Virulence of Brucella, and as Mucosal Adjuvants, Provides an Effective Protection to Mice Against Salmonella Enteritidis.	Chen Y, Fu Y, Kong L, Wang F, Peng X, Zhang Z, Shi Q, Wu Q, Wu T.	Curr Microbiol	10.1007/s00284-022-03107-w	2022
	A two-tier model of polymyxin B resistance in Burkholderia cenocepacia.	Loutet SA, Mussen LE, Flannagan RS, Valvano MA.	Environ Microbiol Rep	10.1111/j.1758-2229.2010.00222.x	2011
	Characterization of the Burkholderia cenocepacia TonB Mutant as a Potential Live Attenuated Vaccine.	Pradenas GA, Myers JN, Torres AG.	Vaccines (Basel)	10.3390/vaccines5040033	2017
	Exploring AI-2-mediated interspecies communications within rumen microbial communities.	Liu X, Liu Q, Sun S, Sun H, Wang Y, Shen X, Zhang L.	Microbiome	10.1186/s40168-022-01367-z	2022
Pathogenicity	BDSF inhibits Candida albicans adherence to urinary catheters.	Tian J, Weng LX, Zhang YQ, Wang LH.	Microb Pathog	10.1016/j.micpath.2013.07.003	2013
	Discovery and biosynthesis of guanipiperazine from a NRPS-like pathway.	Shi J, Xu X, Liu PY, Hu YL, Zhang B, Jiao RH, Bashiri G, Tan RX, Ge HM.	Chem Sci	10.1039/d0sc06135b	2021
Phenotype	Niche-specific metabolic phenotypes can be used to identify antimicrobial targets in pathogens.	Glass EM, Dillard LR, Kolling GL, Warren AS, Papin JA.	PLoS Biol	10.1371/journal.pbio.3002907	2024
	Chromosome translocation and its consequence in the genome of Burkholderia cenocepacia AU-1054.	Guo FB, Ning LW, Huang J, Lin H, Zhang HX.	Biochem Biophys Res Commun	10.1016/j.bbrc.2010.11.039	2010
	Evaluation of the electron transfer flavoprotein as an antibacterial target in Burkholderia cenocepacia.	Stietz MS, Lopez C, Osifo O, Tolmasky ME, Cardona ST.	Can J Microbiol	10.1139/cjm-2017-0350	2017
	Variation of Burkholderia cenocepacia virulence potential during cystic fibrosis chronic lung infection.	Moreira AS, Mil-Homens D, Sousa SA, Coutinho CP, Pinto-de-Oliveira A, Ramos CG, Dos Santos SC, Fialho AM, Leitao JH, Sa-Correia I.	Virulence	10.1080/21505594.2016.1237334	2017
Pathogenicity	Antibacterial contact-dependent proteins secreted by Gram-negative cystic fibrosis respiratory pathogens.	Crisan CV, Goldberg JB.	Trends Microbiol	10.1016/j.tim.2022.03.009	2022
	Architecture and matrix assembly determinants of Bordetella pertussis biofilms on primary human airway epithelium.	Fullen AR, Gutierrez-Ferman JL, Rayner RE, Kim SH, Chen P, Dubey P, Wozniak DJ, Peeples ME, Cormet-Boyaka E, Deora R.	PLoS Pathog	10.1371/journal.ppat.1011193	2023
Pathogenicity	Human Cryptic Host Defence Peptide GVF27 Exhibits Anti-Infective Properties against Biofilm Forming Members of the Burkholderia cepacia Complex.	Bosso A, Gaglione R, Di Girolamo R, Veldhuizen EJA, Garcia-Vello P, Fusco S, Cafaro V, Monticelli M, Culurciello R, Notomista E, Arciello A, Pizzo E.	Pharmaceuticals (Basel)	10.3390/ph15020260	2022
Metabolism	The pobA gene of Burkholderia cenocepacia encodes a group I Sfp-type phosphopantetheinyltransferase required for biosynthesis of the siderophores ornibactin and pyochelin.	Asghar AH, Shastri S, Dave E, Wowk I, Agnoli K, Cook AM, Thomas MS.	Microbiology (Reading)	10.1099/mic.0.045559-0	2011
	Prophylactic phage biocontrol prevents Burkholderia gladioli infection in a quantitative ex planta model of bacterial virulence.	Lauman P, Dennis JJ.	Appl Environ Microbiol	10.1128/aem.01317-24	2024
Metabolism	Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria.	Ryan RP, Dow JM.	Trends Microbiol	10.1016/j.tim.2010.12.003	2011
Metabolism	cAbl Kinase Regulates Inflammasome Activation and Pyroptosis via ASC Phosphorylation.	Gavrilin MA, Prather ER, Vompe AD, McAndrew CC, Wewers MD.	J Immunol	10.4049/jimmunol.2000969	2021
Genetics	Isolation and Characterization of Lytic Proteus Virus 309.	Aaron J, van Zyl LJ, Dicks LMT.	Viruses	10.3390/v14061309	2022
	Chlorhexidine as a Disinfectant in the Prosthodontic Practice: A Comprehensive Review.	Alqarni H, Jamleh A, Chamber MS.	Cureus	10.7759/cureus.30566	2022
	Pharmacological effects of baicalin in lung diseases.	Wang D, Li Y.	Front Pharmacol	10.3389/fphar.2023.1188202	2023
Metabolism	Quantitative proteomics (2-D DIGE) reveals molecular strategies employed by Burkholderia cenocepacia to adapt to the airways of cystic fibrosis patients under antimicrobial therapy.	Madeira A, Santos PM, Coutinho CP, Pinto-de-Oliveira A, Sa-Correia I.	Proteomics	10.1002/pmic.201000457	2011
Enzymology	Who's at The Door? - Surface Contamination of Door Frames in a Single-Bedded In-Patient Adult Cystic Fibrosis (CF) Unit.	Furukawa M, McCaughan J, Stirling J, Millar BC, Addy C, Caskey S, Goldsmith CE, Rendall JC, Misawa N, Downey DG, Moore JE.	Ulster Med J		2020
	Novel co-culture plate enables growth dynamic-based assessment of contact-independent microbial interactions.	Moutinho TJ, Panagides JC, Biggs MB, Medlock GL, Kolling GL, Papin JA.	PLoS One	10.1371/journal.pone.0182163	2017
Metabolism	The Burkholderia cenocepacia K56-2 pleiotropic regulator Pbr, is required for stress resistance and virulence.	Ramos CG, Sousa SA, Grilo AM, Eberl L, Leitao JH.	Microb Pathog	10.1016/j.micpath.2010.02.006	2010
Metabolism	A sensor kinase recognizing the cell-cell signal BDSF (cis-2-dodecenoic acid) regulates virulence in Burkholderia cenocepacia.	McCarthy Y, Yang L, Twomey KB, Sass A, Tolker-Nielsen T, Mahenthiralingam E, Dow JM, Ryan RP.	Mol Microbiol	10.1111/j.1365-2958.2010.07285.x	2010
Metabolism	Biochemical Characterization of Glutamate Racemase-A New Candidate Drug Target against Burkholderia cenocepacia Infections.	Israyilova A, Buroni S, Forneris F, Scoffone VC, Shixaliyev NQ, Riccardi G, Chiarelli LR.	PLoS One	10.1371/journal.pone.0167350	2016
Pathogenicity	Aspergillus fumigatus Supernatants Disrupt Bronchial Epithelial Monolayers: Potential Role for Enhanced Invasion in Cystic Fibrosis.	Dunne K, Reece E, McClean S, Doyle S, Rogers TR, Murphy P, Renwick J.	J Fungi (Basel)	10.3390/jof9040490	2023
Metabolism	Expression and characterization of penicillin-binding proteins in Burkholderia cenocepacia.	Specht KM, Sheetz KH, Alexander CM, Lamech LT, O'Connor LH, Walker DM, Stevenson HP.	Curr Microbiol	10.1007/s00284-009-9537-1	2010
	Evaluation of antimicrobial susceptibility testing methods for Burkholderia cepacia complex isolates from people with and without cystic fibrosis.	Jorth P, Manuel C, McLemore T, Humphries RM, Cole NC, Schuetz AN, Garica D, Maldonado M, Rivero N, Milesi Galdino AC, Celedonio D, LiPuma JJ, Green DA, Zlosnik JEA, Traczewski M, Huse HK.	J Clin Microbiol	10.1128/jcm.01480-24	2025
	Virulence traits associated with Burkholderia cenocepacia ST856 epidemic strain isolated from cystic fibrosis patients.	Malesevic M, Vasiljevic Z, Sovtic A, Filipic B, Novovic K, Kojic M, Jovcic B.	Antimicrob Resist Infect Control	10.1186/s13756-017-0215-y	2017
	What matters in chronic Burkholderia cenocepacia infection in cystic fibrosis: Insights from comparative genomics.	Nunvar J, Capek V, Fiser K, Fila L, Drevinek P.	PLoS Pathog	10.1371/journal.ppat.1006762	2017
	Burkholderia cenocepacia in cystic fibrosis: epidemiology and molecular mechanisms of virulence.	Drevinek P, Mahenthiralingam E.	Clin Microbiol Infect	10.1111/j.1469-0691.2010.03237.x	2010
	In Silico Analysis of a GH3 beta-Glucosidase from Microcystis aeruginosa CACIAM 03.	Serra GM, Siqueira AS, de Molfetta FA, Santos AV, Xavier LP.	Microorganisms	10.3390/microorganisms11040998	2023
Metabolism	Increased electrical output when a bacterial ABTS oxidizer is used in a microbial fuel cell.	Hunter WJ, Manter DK.	Curr Microbiol	10.1007/s00284-010-9755-6	2011
	An intrinsically disordered antimicrobial peptide dendrimer from stereorandomized virtual screening.	Cai X, Orsi M, Capecchi A, Kohler T, van Delden C, Javor S, Reymond JL.	Cell Rep Phys Sci	10.1016/j.xcrp.2022.101161	2022
	Stenotrophomonas maltophilia virulence: a current view.	Mikhailovich V, Heydarov R, Zimenkov D, Chebotar I.	Front Microbiol	10.3389/fmicb.2024.1385631	2024
	Elexacaftor/tezacaftor/ivacaftor corrects monocyte microbicidal deficiency in cystic fibrosis.	Cavinato L, Luly FR, Pastore V, Chiappetta D, Sangiorgi G, Ferrara E, Baiocchi P, Mandarello G, Cimino G, Del Porto P, Ascenzioni F.	Eur Respir J	10.1183/13993003.00725-2022	2023
	Hypermutability bypasses genetic constraints in SCV phenotypic switching in Pseudomonas aeruginosa biofilms.	Tobares RA, Martino RA, Colque CA, Castillo Moro GL, Moyano AJ, Albarracin Orio AG, Smania AM.	NPJ Biofilms Microbiomes	10.1038/s41522-024-00644-z	2025
	Analysis of ParB-centromere interactions by multiplex SPR imaging reveals specific patterns for binding ParB in six centromeres of Burkholderiales chromosomes and plasmids.	Pillet F, Passot FM, Pasta F, Anton Leberre V, Bouet JY.	PLoS One	10.1371/journal.pone.0177056	2017
	Antimicrobial Peptides Originating from Expression Libraries of Aurelia aurita and Mnemiopsis leidyi Prevent Biofilm Formation of Opportunistic Pathogens.	Ladewig L, Gloy L, Langfeldt D, Pinnow N, Weiland-Brauer N, Schmitz RA.	Microorganisms	10.3390/microorganisms11092184	2023
Metabolism	The many uses of autophagosomes.	Amer AO.	Autophagy	10.4161/auto.24146	2013
	[Recurrent tonsillopharyngitis associated with Burkholderia cenocepacia : two case reports].	Zautner AE, Krause M, Stropahl G, Podbielski A.	HNO	10.1007/s00106-008-1789-8	2009
	Biofilm Formation of Pseudomonas aeruginosa in Cystic Fibrosis: Mechanisms of Persistence, Adaptation, and Pathogenesis.	Borisova D, Paunova-Krasteva T, Strateva T, Stoitsova S.	Microorganisms	10.3390/microorganisms13071527	2025
Genetics	Comprehensive genome analysis of Burkholderia contaminans SK875, a quorum-sensing strain isolated from the swine.	Kim E, Jung HI, Park SH, Kim HY, Kim SK.	AMB Express	10.1186/s13568-023-01537-8	2023
Metabolism	Requirement for asparagine in the aquaporin NPA sequence signature motifs for cation exclusion.	Wree D, Wu B, Zeuthen T, Beitz E.	FEBS J	10.1111/j.1742-4658.2010.07993.x	2011
	Anesthetic considerations in lung transplantation: past, present and future.	Murray AW, Boisen ML, Fritz A, Renew JR, Martin AK.	J Thorac Dis	10.21037/jtd-2021-10	2021
	The in vivo extracellular life of facultative intracellular bacterial parasites: role in pathogenesis.	Silva MT, Pestana NT.	Immunobiology	10.1016/j.imbio.2012.05.011	2013
Pathogenicity	Elucidation of the mechanism behind the potentiating activity of baicalin against Burkholderia cenocepacia biofilms.	Slachmuylders L, Van Acker H, Brackman G, Sass A, Van Nieuwerburgh F, Coenye T.	PLoS One	10.1371/journal.pone.0190533	2018
	Rhizoviticin is an alphaproteobacterial tailocin that mediates biocontrol of grapevine crown gall disease.	Ishii T, Tsuchida N, Hemelda NM, Saito K, Bao J, Watanabe M, Toyoda A, Matsubara T, Sato M, Toyooka K, Ishihama N, Shirasu K, Matsui H, Toyoda K, Ichinose Y, Hayashi T, Kawaguchi A, Noutoshi Y.	ISME J	10.1093/ismejo/wrad003	2024
	Lactobacillus acidophilus suppresses non-alcoholic fatty liver disease-associated hepatocellular carcinoma through producing valeric acid.	Lau HC, Zhang X, Ji F, Lin Y, Liang W, Li Q, Chen D, Fong W, Kang X, Liu W, Chu ES, Ng QW, Yu J.	EBioMedicine	10.1016/j.ebiom.2023.104952	2024
	High-Dose Inhaled Nitric Oxide as Adjunct Therapy in Cystic Fibrosis Targeting Burkholderia multivorans.	Bartley BL, Gardner KJ, Spina S, Hurley BP, Campeau D, Berra L, Yonker LM, Carroll RW.	Case Rep Pediatr	10.1155/2020/1536714	2020
Metabolism	Bovine lactoferrin interacts with cable pili of Burkholderia cenocepacia.	Ammendolia MG, Bertuccini L, Iosi F, Minelli F, Berlutti F, Valenti P, Superti F.	Biometals	10.1007/s10534-010-9333-1	2010
	A bacterial pigment provides cross-species protection from H₂O₂- and neutrophil-mediated killing.	Liu Y, McQuillen EA, Rana PSJB, Gloag ES, Parsek MR, Wozniak DJ.	Proc Natl Acad Sci U S A	10.1073/pnas.2312334121	2024
	Adaptation to Overflow Metabolism by Mutations That Impair tRNA Modification in Experimentally Evolved Bacteria.	Muraski MJ, Nilsson EM, Fritz MJ, Richardson AR, Alexander RW, Cooper VS.	mBio	10.1128/mbio.00287-23	2023
	Genomic adaptations of Vibrio campbellii to thermal and salinity stress: insights into marine pathogen resilience in a changing ocean	Pattano J, Dechathai T, Chaichanit N, Surachat K, Jetwanna K, Srinitiwarawong K, Mittraparp-arthorn P.	BMC Genomics		2025
Transcriptome	Microbial gene expression during hibernation in arctic ground squirrels: greater differences across gut sections than in response to pre-hibernation dietary protein content.	Grond K, Buck CL, Duddleston KN.	Front Genet	10.3389/fgene.2023.1210143	2023
	Identification of Bacteria and Viruses Associated with Patients with Acute Febrile Illness in Khon Kaen Province, Thailand.	Jitvaropas R, Sawaswong V, Poovorawan Y, Auysawasdi N, Vuthitanachot V, Wongwairot S, Rodkvamtook W, Lindroth E, Payungporn S, Linsuwanon P.	Viruses	10.3390/v16040630	2024
	Successful treatment of cepacia syndrome with a combination of intravenous cyclosporin, antibiotics and oral corticosteroids.	Gilchrist FJ, Webb AK, Bright-Thomas RJ, Jones AM.	J Cyst Fibros	10.1016/j.jcf.2012.04.002	2012
	The afc antifungal activity cluster, which is under tight regulatory control of ShvR, is essential for transition from intracellular persistence of Burkholderia cenocepacia to acute pro-inflammatory infection.	Gomes MC, Tasrini Y, Subramoni S, Agnoli K, Feliciano JR, Eberl L, Sokol P, O'Callaghan D, Vergunst AC.	PLoS Pathog	10.1371/journal.ppat.1007473	2018
	A TNF-like trimeric lectin domain from Burkholderia cenocepacia with specificity for fucosylated human histo-blood group antigens.	Sulak O, Cioci G, Delia M, Lahmann M, Varrot A, Imberty A, Wimmerova M.	Structure	10.1016/j.str.2009.10.021	2010
Enzymology	Occurrence and antibiotic susceptibility profiles of Burkholderia cepacia complex in coastal marine environment.	Maravic A, Skocibusic M, Sprung M, Samanic I, Puizina J, Pavela-Vrancic M.	Int J Environ Health Res	10.1080/09603123.2012.667797	2012
	Induced Burkholderia prophages detected from the hemoculture: a biomarker for Burkholderia pseudomallei infection.	Withatanung P, Janesomboon S, Vanaporn M, Muangsombut V, Charoensudjai S, Baker DJ, Wuthiekanun V, Galyov EE, Clokie MRJ, Gundogdu O, Korbsrisate S.	Front Microbiol	10.3389/fmicb.2024.1361121	2024
Enzymology	Directed evolution engineering to improve activity of glucose dehydrogenase by increasing pocket hydrophobicity.	Hua L, Qianqian B, Jianfeng Z, Yinbiao X, Shengyu Y, Weishi X, Yang S, Yupeng L.	Front Microbiol	10.3389/fmicb.2022.1044226	2022
Genetics	The Essential Genome of Burkholderia cenocepacia H111.	Higgins S, Sanchez-Contreras M, Gualdi S, Pinto-Carbo M, Carlier A, Eberl L.	J Bacteriol	10.1128/jb.00260-17	2017
	Engineering quorum quenching acylases with improved kinetic and biochemical properties.	Sompiyachoke K, Elias MH.	Protein Sci	10.1002/pro.4954	2024
Pathogenicity	Effect of nitrofurans and NO generators on biofilm formation by Pseudomonas aeruginosa PAO1 and Burkholderia cenocepacia 370.	Zaitseva J, Granik V, Belik A, Koksharova O, Khmel I.	Res Microbiol	10.1016/j.resmic.2009.04.007	2009
	Complementary Regulation of BfmRS Two-Component and AbaIR Quorum Sensing Systems to Express Virulence-Associated Genes in Acinetobacter baumannii.	Kim HJ, Kim NY, Ko SY, Park SY, Oh MH, Shin MS, Lee YC, Lee JC.	Int J Mol Sci	10.3390/ijms232113136	2022
	The Arabinose 5-Phosphate Isomerase KdsD Is Required for Virulence in Burkholderia pseudomallei.	Jenkins CH, Scott AE, O'Neill PA, Norville IH, Prior JL, Ireland PM.	J Bacteriol	10.1128/jb.00034-23	2023
	Burkholderia multivorans survival and trafficking within macrophages.	Schmerk CL, Valvano MA.	J Med Microbiol	10.1099/jmm.0.051243-0	2013
Metabolism	Burkholderia cenocepacia zinc metalloproteases influence resistance to antimicrobial peptides.	Kooi C, Sokol PA.	Microbiology (Reading)	10.1099/mic.0.028969-0	2009
Metabolism	Three Rings to Rule Them All: How Versatile Flavoenzymes Orchestrate the Structural Diversification of Natural Products.	Toplak M, Teufel R.	Biochemistry	10.1021/acs.biochem.1c00763	2022
	Quorum sensing regulates heteroresistance in Pseudomonas aeruginosa.	Lu Y, Liu Y, Zhou C, Liu Y, Long Y, Lin D, Xiong R, Xiao Q, Huang B, Chen C.	Front Microbiol	10.3389/fmicb.2022.1017707	2022
	Anti-virulence and bactericidal activities of Stattic against Shigella sonnei.	Wang M, Zeng J, Tan H, Guo Q, Li X, Ling X, Zhang J, Song S, Deng Y.	Appl Environ Microbiol	10.1128/aem.01074-23	2023
Pathogenicity	Two case reports of the successful eradication of new isolates of Burkholderia cepacia complex in children with cystic fibrosis.	Kitt H, Lenney W, Gilchrist FJ.	BMC Pharmacol Toxicol	10.1186/s40360-016-0054-0	2016
	Virulence of an emerging respiratory pathogen, genus Pandoraea, in vivo and its interactions with lung epithelial cells.	Costello A, Herbert G, Fabunmi L, Schaffer K, Kavanagh KA, Caraher EM, Callaghan M, McClean S.	J Med Microbiol	10.1099/jmm.0.022657-0	2011
Metabolism	Identification of small RNAs abundant in Burkholderia cenocepacia biofilms reveal putative regulators with a potential role in carbon and iron metabolism.	Sass A, Kiekens S, Coenye T.	Sci Rep	10.1038/s41598-017-15818-3	2017
Phylogeny	Strains of Burkholderia cenocepacia genomovar IIIA possessing the cblA gene that are distinct from ET12.	Turton JF, O'Brien E, Megson B, Kaufmann ME, Pitt TL.	Diagn Microbiol Infect Dis	10.1016/j.diagmicrobio.2009.01.010	2009
Pathogenicity	Triclosan Is an Aminoglycoside Adjuvant for Eradication of Pseudomonas aeruginosa Biofilms.	Maiden MM, Hunt AMA, Zachos MP, Gibson JA, Hurwitz ME, Mulks MH, Waters CM.	Antimicrob Agents Chemother	10.1128/aac.00146-18	2018
	Antimicrobial Peptide-Peptoid Hybrids with and without Membrane Disruption.	Bonvin E, Personne H, Paschoud T, Reusser J, Gan BH, Luscher A, Kohler T, van Delden C, Reymond JL.	ACS Infect Dis	10.1021/acsinfecdis.3c00421	2023
Metabolism	Burkholderia cenocepacia O antigen lipopolysaccharide prevents phagocytosis by macrophages and adhesion to epithelial cells.	Saldias MS, Ortega X, Valvano MA.	J Med Microbiol	10.1099/jmm.0.013235-0	2009
	Kanglemycin A Can Overcome Rifamycin Resistance Caused by ADP-Ribosylation by Arr Protein.	Harbottle J, Mosaei H, Allenby N, Zenkin N.	Antimicrob Agents Chemother	10.1128/aac.00864-21	2021
Pathogenicity	Mechanism of resistance to an antitubercular 2-thiopyridine derivative that is also active against Burkholderia cenocepacia.	Scoffone VC, Spadaro F, Udine C, Makarov V, Fondi M, Fani R, De Rossi E, Riccardi G, Buroni S.	Antimicrob Agents Chemother	10.1128/aac.02438-13	2014
Metabolism	NtrC-dependent control of exopolysaccharide synthesis and motility in Burkholderia cenocepacia H111.	Liu Y, Lardi M, Pedrioli A, Eberl L, Pessi G.	PLoS One	10.1371/journal.pone.0180362	2017
Metabolism	Burkholderia cenocepacia: a new biocatalyst for efficient bioreduction of ezetimibe intermediate.	Singh A, Basit A, Banerjee UC.	J Ind Microbiol Biotechnol	10.1007/s10295-009-0622-z	2009
	A study on bacteria associated with the intestinal tract of farmed yellow seahorse, Hippocampus kuda (Bleeker, 1852): characterization and extracellular enzymes	Tanu , Deobagkar DD, Khandeparker R, Sreepada RA, Sanaye SV, Pawar HB.	Aquac Res	10.1111/j.1365-2109.2011.02841.x	2012
	Isolation of cadmium-resistance and siderophore-producing endophytic bacteria and their potential use for soil cadmium remediation.	Li Y, Wei S, Chen X, Dong Y, Zeng M, Yan C, Hou L, Jiao R.	Heliyon	10.1016/j.heliyon.2023.e17661	2023
	Epidemiology and molecular characterization of a clone of Burkholderia cenocepacia responsible for nosocomial pulmonary tract infections in a French intensive care unit.	Graindorge A, Menard A, Neto M, Bouvet C, Miollan R, Gaillard S, de Montclos H, Laurent F, Cournoyer B.	Diagn Microbiol Infect Dis	10.1016/j.diagmicrobio.2009.06.008	2010
Metabolism	Structural basis of the affinity for oligomannosides and analogs displayed by BC2L-A, a Burkholderia cenocepacia soluble lectin.	Lameignere E, Shiao TC, Roy R, Wimmerova M, Dubreuil F, Varrot A, Imberty A.	Glycobiology	10.1093/glycob/cwp151	2010
Genetics	Genomics Reveals a Unique Clone of Burkholderia cenocepacia Harboring an Actively Excising Novel Genomic Island.	Patil PP, Mali S, Midha S, Gautam V, Dash L, Kumar S, Shastri J, Singhal L, Patil PB.	Front Microbiol	10.3389/fmicb.2017.00590	2017
	Multitasking functions of bacterial extracellular DNA in biofilms.	Sharma DK, Rajpurohit YS.	J Bacteriol	10.1128/jb.00006-24	2024
Metabolism	Burkholderia PglL enzymes are Serine preferring oligosaccharyltransferases which target conserved proteins across the Burkholderia genus.	Hayes AJ, Lewis JM, Davies MR, Scott NE.	Commun Biol	10.1038/s42003-021-02588-y	2021
Pathogenicity	Interactions of Burkholderia cenocepacia and other Burkholderia cepacia complex bacteria with epithelial and phagocytic cells.	Saldias MS, Valvano MA.	Microbiology (Reading)	10.1099/mic.0.031344-0	2009
	Interspecies surfactants serve as public goods enabling surface motility in Pseudomonas aeruginosa.	Warrell DL, Zarrella TM, Machalek C, Khare A.	J Bacteriol	10.1128/jb.00281-24	2024
	Mitigation of Pseudomonas syringae virulence by signal inactivation.	Sieber S, Mathew A, Jenul C, Kohler T, Bar M, Carrion VJ, Cazorla FM, Stalder U, Hsieh YC, Bigler L, Eberl L, Gademann K.	Sci Adv	10.1126/sciadv.abg2293	2021
	Using anti-biofilm peptides to treat antibiotic-resistant bacterial infections.	de la Fuente-Nunez C, Hancock RE.	Postdoc J	10.14304/surya.jpr.v3n2.1	2015
	Improved Dynamic Range of a Rhamnose-Inducible Promoter for Gene Expression in Burkholderia spp.	Hogan AM, Jeffers KR, Palacios A, Cardona ST.	Appl Environ Microbiol	10.1128/aem.00647-21	2021
	Mutational spectra are associated with bacterial niche.	Ruis C, Weimann A, Tonkin-Hill G, Pandurangan AP, Matuszewska M, Murray GGR, Levesque RC, Blundell TL, Floto RA, Parkhill J.	Nat Commun	10.1038/s41467-023-42916-w	2023
Metabolism	Regulation of Burkholderia cenocepacia biofilm formation by RpoN and the c-di-GMP effector BerB.	Fazli M, Rybtke M, Steiner E, Weidel E, Berthelsen J, Groizeleau J, Bin W, Zhi BZ, Yaming Z, Kaever V, Givskov M, Hartmann RW, Eberl L, Tolker-Nielsen T.	Microbiologyopen	10.1002/mbo3.480	2017
Pathogenicity	In Vitro Activity of a Novel Glycopolymer against Biofilms of Burkholderia cepacia Complex Cystic Fibrosis Clinical Isolates.	Narayanaswamy VP, Duncan AP, LiPuma JJ, Wiesmann WP, Baker SM, Townsend SM.	Antimicrob Agents Chemother	10.1128/aac.00498-19	2019
Enzymology	Should cystic fibrosis patients infected with Burkholderia cepacia complex be listed for lung transplantation?	Olland A, Falcoz PE, Kessler R, Massard G, Massard G.	Interact Cardiovasc Thorac Surg	10.1510/icvts.2011.271874	2011
	Key Players and Individualists of Cyclic-di-GMP Signaling in Burkholderia cenocepacia.	Richter AM, Fazli M, Schmid N, Shilling R, Suppiger A, Givskov M, Eberl L, Tolker-Nielsen T.	Front Microbiol	10.3389/fmicb.2018.03286	2018
Pathogenicity	Differential roles of RND efflux pumps in antimicrobial drug resistance of sessile and planktonic Burkholderia cenocepacia cells.	Buroni S, Matthijs N, Spadaro F, Van Acker H, Scoffone VC, Pasca MR, Riccardi G, Coenye T.	Antimicrob Agents Chemother	10.1128/aac.03800-14	2014
Pathogenicity	The Mla Pathway Plays an Essential Role in the Intrinsic Resistance of Burkholderia cepacia Complex Species to Antimicrobials and Host Innate Components.	Bernier SP, Son S, Surette MG.	J Bacteriol	10.1128/jb.00156-18	2018
	Bacterial Re-Colonization Occurs Early after Lung Transplantation in Cystic Fibrosis Patients.	Holm AE, Schultz HHL, Johansen HK, Pressler T, Lund TK, Iversen M, Perch M.	J Clin Med	10.3390/jcm10061275	2021
	A flow cytometric assay to detect viability and persistence of Salmonella enterica subsp. enterica serotypes in nuclease-free water at 4 and 25°C.	Williams A, Gaoh SD, Savenka A, Paredes A, Alusta P, Ahn Y, Buzatu DA.	Front Microbiol	10.3389/fmicb.2024.1342478	2024
	Pathogen-host interactions in Dictyostelium, Legionella, Mycobacterium and other pathogens.	Steinert M.	Semin Cell Dev Biol	10.1016/j.semcdb.2010.11.003	2011
	Gut Microbiome-Based Analysis of Lipid A Biosynthesis in Individuals with Autism Spectrum Disorder: An In Silico Evaluation.	Maigoro AY, Lee S.	Nutrients	10.3390/nu13020688	2021
Metabolism	Antibiotic interceptors: Creating safe spaces for bacteria.	Sabnis A, Ledger EVK, Pader V, Edwards AM.	PLoS Pathog	10.1371/journal.ppat.1006924	2018
	Mapping Protein-Protein Interactions at Birth: Single-Particle Cryo-EM Analysis of a Ribosome-Nascent Globin Complex.	Masse MM, Hutchinson RB, Morgan CE, Allaman HJ, Guan H, Yu EW, Cavagnero S.	ACS Cent Sci	10.1021/acscentsci.3c00777	2024
Pathogenicity	Discovery of new diketopiperazines inhibiting Burkholderia cenocepacia quorum sensing in vitro and in vivo.	Scoffone VC, Chiarelli LR, Makarov V, Brackman G, Israyilova A, Azzalin A, Forneris F, Riabova O, Savina S, Coenye T, Riccardi G, Buroni S.	Sci Rep	10.1038/srep32487	2016
Metabolism	A c-di-GMP-Modulating Protein Regulates Swimming Motility of Burkholderia cenocepacia in Response to Arginine and Glutamate.	Kumar B, Sorensen JL, Cardona ST.	Front Cell Infect Microbiol	10.3389/fcimb.2018.00056	2018
	Soil-derived Streptomyces sp. GMR22 producing antibiofilm activity against Candida albicans: bioassay, untargeted LC-HRMS, and gene cluster analysis.	Nirwati H, Damayanti E, Sholikhah EN, Mutofa M, Widada J.	Heliyon	10.1016/j.heliyon.2022.e09333	2022
Pathogenicity	Identification of the lipodepsipeptide selethramide encoded in a giant nonribosomal peptide synthetase from a Burkholderia bacterium.	Romanowski SB, Lee S, Kunakom S, Paulo BS, Recchia MJJ, Liu DY, Cavanagh H, Linington RG, Eustaquio AS.	Proc Natl Acad Sci U S A	10.1073/pnas.2304668120	2023
	One gene, multiple ecological strategies: A biofilm regulator is a capacitor for sustainable diversity.	Mhatre E, Snyder DJ, Sileo E, Turner CB, Buskirk SW, Fernandez NL, Neiditch MB, Waters CM, Cooper VS.	Proc Natl Acad Sci U S A	10.1073/pnas.2008540117	2020
Metabolism	Presence of the Hmq System and Production of 4-Hydroxy-3-Methyl-2-Alkylquinolines Are Heterogeneously Distributed between Burkholderia cepacia Complex Species and More Prevalent among Environmental than Clinical Isolates.	Coulon PML, Zlosnik JEA, Deziel E.	Microbiol Spectr	10.1128/spectrum.00127-21	2021
Phenotype	Identification of two distinct phylogenomic lineages and model strains for the understudied cystic fibrosis lung pathogen Burkholderia multivorans.	Parfitt KM, Green AE, Connor TR, Neill DR, Mahenthiralingam E.	Microbiology (Reading)	10.1099/mic.0.001366	2023
	Updated Review on Clinically-Relevant Properties of Delafloxacin.	Turban A, Guerin F, Dinh A, Cattoir V.	Antibiotics (Basel)	10.3390/antibiotics12081241	2023
Pathogenicity	Evaluation of the efficacy of disinfection procedures against Burkholderia cenocepacia biofilms.	Peeters E, Nelis HJ, Coenye T.	J Hosp Infect	10.1016/j.jhin.2008.08.015	2008
Phylogeny	Diversity analysis of Burkholderia cepacia complex in the water bodies of West Lake, Hangzhou, China.	Fang Y, Xie GL, Lou MM, Li B, Muhammad I.	J Microbiol	10.1007/s12275-011-0267-2	2011
	Acute Burkholderia cenocepacia pyomyositis in a patient with cystic fibrosis.	El-Laboudi AH, Etherington C, Whitaker P, Clifton IJ, Conway SP, Denton M, Peckham DG.	J Cyst Fibros	10.1016/j.jcf.2009.04.007	2009
	Virulence Genotype and Correlation of Clinical Severeness with Presence of the Type VI Secretion System in Klebsiella pneumoniae Isolates Causing Bloodstream Infections.	Zhang Y, Xu Y, Huang Y.	Infect Drug Resist	10.2147/idr.s353858	2022
Enzymology	Survival of Burkholderia cepacia sepsis following lung transplantation in recipients with cystic fibrosis.	Nash EF, Coonar A, Kremer R, Tullis E, Hutcheon M, Singer LG, Keshavjee S, Chaparro C.	Transpl Infect Dis	10.1111/j.1399-3062.2010.00525.x	2010
Phylogeny	Analysis of bacterial community using pyrosequencing in semen from patients with chronic pelvic pain syndrome: a pilot study.	Choi JB, Lee SJ, Kang SR, Lee SS, Choe HS.	Transl Androl Urol	10.21037/tau.2020.02.05	2020
	Coarse-grained simulations uncover Gram-negative bacterial defense against polymyxins by the outer membrane.	Jiang X, Sun Y, Yang K, Yuan B, Velkov T, Wang L, Li J.	Comput Struct Biotechnol J	10.1016/j.csbj.2021.06.051	2021
	Drug Discovery in the Field of beta-Lactams: An Academic Perspective.	Jacobs LMC, Consol P, Chen Y.	Antibiotics (Basel)	10.3390/antibiotics13010059	2024
	Navigating collateral sensitivity: insights into the mechanisms and applications of antibiotic resistance trade-offs.	Mahmud HA, Wakeman CA.	Front Microbiol	10.3389/fmicb.2024.1478789	2024
	Bioinformatic and functional characterization of cyclic-di-GMP metabolic proteins in Vibrio alginolyticus unveils key diguanylate cyclases controlling multiple biofilm-associated phenotypes.	Gong XX, Zeng YH, Chen HM, Zhang N, Han Y, Long H, Xie ZY.	Front Microbiol	10.3389/fmicb.2023.1258415	2023
	Zebrafish-based platform for emerging bio-contaminants and virus inactivation research.	Patel P, Nandi A, Verma SK, Kaushik N, Suar M, Choi EH, Kaushik NK.	Sci Total Environ	10.1016/j.scitotenv.2023.162197	2023
	Murine models of acute and chronic lung infection with cystic fibrosis pathogens.	Bragonzi A.	Int J Med Microbiol	10.1016/j.ijmm.2010.08.012	2010
	Sputum from People with Cystic Fibrosis Reduces the Killing of Methicillin-Resistant Staphylococcus aureus by Neutrophils and Diminishes Phagosomal Production of Reactive Oxygen Species.	Fantone KM, Goldberg JB, Stecenko AA, Rada B.	Pathogens	10.3390/pathogens12091148	2023
	Lack of MyD88 protects the immunodeficient host against fatal lung inflammation triggered by the opportunistic bacteria Burkholderia cenocepacia.	Ventura GM, Balloy V, Ramphal R, Khun H, Huerre M, Ryffel B, Plotkowski MC, Chignard M, Si-Tahar M.	J Immunol	10.4049/jimmunol.0801497	2009
	Pseudomonas aeruginosa and Burkholderia cenocepacia infections in patients affected by cystic fibrosis: serum resistance and antibody response.	Savoia D, Deplano C, Zucca M.	Immunol Invest	10.1080/08820130701741775	2008
	Comparing Long-Read Assemblers to Explore the Potential of a Sustainable Low-Cost, Low-Infrastructure Approach to Sequence Antimicrobial Resistant Bacteria With Oxford Nanopore Sequencing.	Boostrom I, Portal EAR, Spiller OB, Walsh TR, Sands K.	Front Microbiol	10.3389/fmicb.2022.796465	2022
	The impact of phage and phage resistance on microbial community dynamics.	Alseth EO, Custodio R, Sundius SA, Kuske RA, Brown SP, Westra ER.	PLoS Biol	10.1371/journal.pbio.3002346	2024
Pathogenicity	Contributions of two UDP-glucose dehydrogenases to viability and polymyxin B resistance of Burkholderia cenocepacia.	Loutet SA, Bartholdson SJ, Govan JRW, Campopiano DJ, Valvano MA.	Microbiology (Reading)	10.1099/mic.0.027607-0	2009
Metabolism	Delayed association of the NADPH oxidase complex with macrophage vacuoles containing the opportunistic pathogen Burkholderia cenocepacia.	Keith KE, Hynes DW, Sholdice JE, Valvano MA.	Microbiology (Reading)	10.1099/mic.0.026781-0	2009
	Inflammasome activation and evasion by bacterial pathogens.	Ta A, Vanaja SK.	Curr Opin Immunol	10.1016/j.coi.2020.11.006	2021
Metabolism	Human Cystic Fibrosis Macrophages Have Defective Calcium-Dependent Protein Kinase C Activation of the NADPH Oxidase, an Effect Augmented by Burkholderia cenocepacia.	Assani K, Shrestha CL, Robledo-Avila F, Rajaram MV, Partida-Sanchez S, Schlesinger LS, Kopp BT.	J Immunol	10.4049/jimmunol.1502609	2017
Enzymology	Isolation of Burkholderia cenocepacia and Burkholderia vietnamiensis from human sewage.	McNeely D, Moore JE, Elborn JS, Millar BC, Rendall J, Dooley JS.	Int J Environ Health Res	10.1080/09603120802392876	2009
	Periodontitis Risk Factors in Adults with Cystic Fibrosis: A pilot study.	Alkhateeb AA, Mancl LA, Ramos KJ, Rothen ML, Kotsakis GA, Trence DL, Chi DL.	J Dent Hyg		2023
	A novel method for investigating Burkholderia cenocepacia infections in patients with cystic fibrosis and other chronic diseases of the airways.	Wijers CD, Vagedes R, Weingart C.	BMC Microbiol	10.1186/s12866-016-0811-7	2016
Enzymology	Two cases of Burkholderia cenocepacia in septicemic patients.	Gautam V, Ray P, Das A, Vandamme P, Malhotra P, Varma S, Vijayvergiya R, Mandal J, Garg N.	Jpn J Infect Dis		2008
	Transcriptional landscape of Burkholderia pseudomallei cultured under environmental and clinical conditions.	Kong C, Wong RR, Ghazali AK, Hara Y, Tengku Aziz TN, Nathan S.	Microb Genom	10.1099/mgen.0.000982	2023
	Community Acquired Burkholderia cepacia Bacteraemia Presenting as MODS in an Immunocompetent Individual: An Unusual Case.	Ranjan R, Chowdhary P, Kamra A.	J Clin Diagn Res	10.7860/jcdr/2017/16285.9435	2017
	Biomedical Promise of Aspergillus Flavus-Biosynthesized Selenium Nanoparticles: A Green Synthesis Approach to Antiviral, Anticancer, Anti-Biofilm, and Antibacterial Applications.	Mohammed EJ, Abdelaziz AEM, Mekky AE, Mahmoud NN, Sharaf M, Al-Habibi MM, Khairy NM, Al-Askar AA, Youssef FS, Gaber MA, Saied E, AbdElgayed G, Metwally SA, Shoun AA.	Pharmaceuticals (Basel)	10.3390/ph17070915	2024
	Response of sessile cells to stress: from changes in gene expression to phenotypic adaptation.	Coenye T.	FEMS Immunol Med Microbiol	10.1111/j.1574-695x.2010.00682.x	2010
	Profiling cell envelope-antibiotic interactions reveals vulnerabilities to beta-lactams in a multidrug-resistant bacterium.	Hogan AM, Rahman ASMZ, Motnenko A, Natarajan A, Maydaniuk DT, Leon B, Batun Z, Palacios A, Bosch A, Cardona ST.	Nat Commun	10.1038/s41467-023-40494-5	2023
	BC2L-C N-Terminal Lectin Domain Complexed with Histo Blood Group Oligosaccharides Provides New Structural Information.	Bermeo R, Bernardi A, Varrot A.	Molecules	10.3390/molecules25020248	2020
Metabolism	Loss of O-Linked Protein Glycosylation in Burkholderia cenocepacia Impairs Biofilm Formation and Siderophore Activity and Alters Transcriptional Regulators.	Oppy CC, Jebeli L, Kuba M, Oates CV, Strugnell R, Edgington-Mitchell LE, Valvano MA, Hartland EL, Newton HJ, Scott NE.	mSphere	10.1128/msphere.00660-19	2019
	The maturation of native uropathogenic Escherichia coli biofilms seen through a non-interventional lens.	Zhang T, Ray S, Melican K, Richter-Dahlfors A.	Biofilm	10.1016/j.bioflm.2024.100212	2024
Pathogenicity	Use of quorum sensing inhibitors to interfere with biofilm formation and development in Burkholderia multivorans and Burkholderia cenocepacia.	Brackman G, Hillaert U, Van Calenbergh S, Nelis HJ, Coenye T.	Res Microbiol	10.1016/j.resmic.2008.12.003	2009
	Impact of Temperature and Oxygen Availability on Gene Expression Patterns of Mycobacterium ulcerans.	Dhungel L, Bonner R, Cook M, Henson D, Moulder T, Benbow ME, Jordan H.	Microbiol Spectr	10.1128/spectrum.04968-22	2023
Metabolism	Identification of sodium chloride-regulated genes in Burkholderia cenocepacia.	Bhatt S, Weingart CL.	Curr Microbiol	10.1007/s00284-008-9114-z	2008
	Gene expression profiling of Burkholderia cenocepacia at the time of cepacia syndrome: loss of motility as a marker of poor prognosis?	Kalferstova L, Kolar M, Fila L, Vavrova J, Drevinek P.	J Clin Microbiol	10.1128/jcm.03605-14	2015
Enzymology	Novel glycopolymer sensitizes Burkholderia cepacia complex isolates from cystic fibrosis patients to tobramycin and meropenem.	Narayanaswamy VP, Giatpaiboon S, Baker SM, Wiesmann WP, LiPuma JJ, Townsend SM.	PLoS One	10.1371/journal.pone.0179776	2017
Metabolism	A biosurfactant from Burkholderia cenocepacia BSP3 and its enhancement of pesticide solubilization.	Wattanaphon HT, Kerdsin A, Thammacharoen C, Sangvanich P, Vangnai AS.	J Appl Microbiol	10.1111/j.1365-2672.2008.03755.x	2008
Metabolism	Invasion of Burkholderia cepacia complex isolates into lung epithelial cells involves glycolipid receptors.	Mullen T, Callaghan M, McClean S.	Microb Pathog	10.1016/j.micpath.2010.08.003	2010
Metabolism	The IclR-family regulator BapR controls biofilm formation in B. cenocepacia H111.	Aguilar C, Schmid N, Lardi M, Pessi G, Eberl L.	PLoS One	10.1371/journal.pone.0092920	2014
Pathogenicity	In vitro interactions of tobramycin with various nonantibiotics against Pseudomonas aeruginosa and Burkholderia cenocepacia.	Treerat P, Widmer F, Middleton PG, Iredell J, George AM.	FEMS Microbiol Lett	10.1111/j.1574-6968.2008.01219.x	2008
	Burkholderia cenocepacia strains isolated from cystic fibrosis patients are apparently more invasive and more virulent than rhizosphere strains.	Pirone L, Bragonzi A, Farcomeni A, Paroni M, Auriche C, Conese M, Chiarini L, Dalmastri C, Bevivino A, Ascenzioni F.	Environ Microbiol	10.1111/j.1462-2920.2008.01697.x	2008
Genetics	Identification and analysis of genomic islands in Burkholderia cenocepacia AU 1054 with emphasis on pathogenicity islands.	Guo FB, Xiong L, Zhang KY, Dong C, Zhang FZ, Woo PC.	BMC Microbiol	10.1186/s12866-017-0986-6	2017
Genetics	SOCfinder: a genomic tool for identifying social genes in bacteria.	Belcher LJ, Dewar AE, Hao C, Katz Z, Ghoul M, West SA.	Microb Genom	10.1099/mgen.0.001171	2023
Metabolism	TLR 5, but neither TLR2 nor TLR4, is involved in lung epithelial cell response to Burkholderia cenocepacia.	de C Ventura GM, Le Goffic R, Balloy V, Plotkowski MC, Chignard M, Si-Tahar M.	FEMS Immunol Med Microbiol	10.1111/j.1574-695x.2008.00453.x	2008
Metabolism	Synthetic Cystic Fibrosis Sputum Medium Regulates Flagellar Biosynthesis through the flhF Gene in Burkholderia cenocepacia.	Kumar B, Cardona ST.	Front Cell Infect Microbiol	10.3389/fcimb.2016.00065	2016
Metabolism	Iron acquisition in the cystic fibrosis lung and potential for novel therapeutic strategies.	Tyrrell J, Callaghan M.	Microbiology (Reading)	10.1099/mic.0.000220	2016
	Heterometrus Spinifer: An Untapped Source of Anti-Tumor Molecules.	Soopramanien M, Khan NA, Ghimire A, Sagathevan K, Siddiqui R.	Biology (Basel)	10.3390/biology9070150	2020
	Candidate Essential Genes in Burkholderia cenocepacia J2315 Identified by Genome-Wide TraDIS.	Wong YC, Abd El Ghany M, Naeem R, Lee KW, Tan YC, Pain A, Nathan S.	Front Microbiol	10.3389/fmicb.2016.01288	2016
	Community context matters for bacteria-phage ecology and evolution.	Blazanin M, Turner PE.	ISME J	10.1038/s41396-021-01012-x	2021
	X-ray crystal structures of the pheromone-binding domains of two quorum-hindered transcription factors, YenR of Yersinia enterocolitica and CepR2 of Burkholderia cenocepacia.	Kim Y, Chhor G, Tsai CS, Fox G, Chen CS, Winans NJ, Jedrzejczak R, Joachimiak A, Winans SC.	Proteins	10.1002/prot.25336	2017
	2-Heptylcyclopropane-1-Carboxylic Acid Disperses and Inhibits Bacterial Biofilms.	Harrison ZL, Awais R, Harris M, Raji B, Hoffman BC, Baker DL, Jennings JA.	Front Microbiol	10.3389/fmicb.2021.645180	2021
	Cystic Fibrosis: From Qualification to Lung Transplantation, a Single Center Experience.	Ochman M, Latos M, Urlik M, Stacel T, Necki M, Tatoj Z, Zawadzki F, Wajda-Pokrontka M, Przybylowski P, Zembala M.	Ann Transplant	10.12659/aot.914328	2019
Pathogenicity	Evolution of Acinetobacter baumannii in Clinical Bacteremia Patients.	Li H, Zhang J, Wang Z, Yin Y, Gao H, Wang R, Jin L, Wang Q, Zhao C, Wang Z, Wang H.	Infect Drug Resist	10.2147/idr.s320645	2021
	Differential modulation of innate immune cell functions by the Burkholderia cepacia complex: Burkholderia cenocepacia but not Burkholderia multivorans disrupts maturation and induces necrosis in human dendritic cells.	MacDonald KL, Speert DP.	Cell Microbiol	10.1111/j.1462-5822.2008.01197.x	2008
	A Disturbed Siderophore Transport Inhibits Myxobacterial Predation.	Dong Y, Dong H, Feng Z, Wang X, Yao Q, Zhu H.	Cells	10.3390/cells11233718	2022
	Induction of immune response to the 17 kDa OMPA Burkholderia cenocepacia polypeptide and protection against pulmonary infection in mice after nasal vaccination with an OMP nanoemulsion-based vaccine.	Makidon PE, Knowlton J, Groom JV, Blanco LP, LiPuma JJ, Bielinska AU, Baker JR.	Med Microbiol Immunol	10.1007/s00430-009-0137-2	2010
	¹H-NMR-Based Endometabolome Profiles of Burkholderia cenocepacia Clonal Variants Retrieved from a Cystic Fibrosis Patient during Chronic Infection.	Moreira AS, Lourenco AB, Sa-Correia I.	Front Microbiol	10.3389/fmicb.2016.02024	2016
	Metagenomic analysis for taxonomic and functional potential of Polyaromatic hydrocarbons (PAHs) and Polychlorinated biphenyl (PCB) degrading bacterial communities in steel industrial soil.	Sandhu M, Paul AT, Jha PN.	PLoS One	10.1371/journal.pone.0266808	2022
Enzymology	How Three Self-Secreted Biofilm Exopolysaccharides of Pseudomonas aeruginosa, Psl, Pel, and Alginate, Can Each Be Exploited for Antibiotic Adjuvant Effects in Cystic Fibrosis Lung Infection.	Chung J, Eisha S, Park S, Morris AJ, Martin I.	Int J Mol Sci	10.3390/ijms24108709	2023
	Two Enteropathogenic Escherichia coli Strains Representing Novel Serotypes and Investigation of Their Roles in Adhesion.	Wang J, Jiao H, Zhang X, Zhang Y, Sun N, Yang Y, Wei Y, Hu B, Guo X.	J Microbiol Biotechnol	10.4014/jmb.2105.05016	2021
	Group B streptococcus (GBS) is an important pathogen in human disease- but what about in cystic fibrosis?	Skolnik K, Nguyen A, Thornton CS, Waddell B, Williamson T, Rabin HR, Parkins MD.	BMC Infect Dis	10.1186/s12879-017-2729-6	2017
	A smooth vetch (Vicia villosa var.) strain endogenous to the broad-spectrum antagonist Bacillus siamensis JSZ06 alleviates banana wilt disease.	Ruan YN, Nong C, Jintrawet A, Fan H, Fu L, Zheng SJ, Li S, Wang ZY.	Front Plant Sci	10.3389/fpls.2024.1410197	2024
Pathogenicity	Bovine lactoferrin inhibits the efficiency of invasion of respiratory A549 cells of different iron-regulated morphological forms of Pseudomonas aeruginosa and Burkholderia cenocepacia.	Berlutti F, Superti F, Nicoletti M, Morea C, Frioni A, Ammendolia MG, Battistoni A, Valenti P.	Int J Immunopathol Pharmacol	10.1177/039463200802100107	2008
Pathogenicity	The Impact of Intraspecies and Interspecies Bacterial Interactions on Disease Outcome.	Baishya J, Bisht K, Rimbey JN, Yihunie KD, Islam S, Al Mahmud H, Waller JE, Wakeman CA.	Pathogens	10.3390/pathogens10020096	2021
	Fostering Innovation in the Treatment of Chronic Polymicrobial Cystic Fibrosis-Associated Infections Exploring Aspartic Acid and Succinic Acid as Ciprofloxacin Adjuvants.	Silva E, Monteiro R, Grainha T, Alves D, Pereira MO, Sousa AM.	Front Cell Infect Microbiol	10.3389/fcimb.2020.00441	2020
	Burkholderia ubonensis High-Level Tetracycline Resistance Is Due to Efflux Pump Synergy Involving a Novel TetA(64) Resistance Determinant.	Somprasong N, Hall CM, Webb JR, Sahl JW, Wagner DM, Keim P, Currie BJ, Schweizer HP.	Antimicrob Agents Chemother	10.1128/aac.01767-20	2021
	Stress Tolerance and Virulence-Related Roles of Lipopolysaccharide in Burkholderia glumae.	Lee C, Mannaa M, Kim N, Kim J, Choi Y, Kim SH, Jung B, Lee HH, Lee J, Seo YS.	Plant Pathol J	10.5423/ppj.oa.04.2019.0124	2019
	Transendothelial migration of the Lyme disease spirochete involves spirochete internalization as an intermediate step through a transcellular pathway that involves Cdc42 and Rac1.	Alvarez-Olmedo D, Kamaliddin C, Verhey TB, Ho M, De Vinney R, Chaconas G.	Microbiol Spectr	10.1128/spectrum.02221-24	2025
	Functionality of chimeric TssA proteins in the type VI secretion system reveals sheath docking specificity within their N-terminal domains.	Fecht S, Paracuellos P, Subramoni S, Tan CAZ, Ilangovan A, Costa TRD, Filloux A.	Nat Commun	10.1038/s41467-024-48487-8	2024
Metabolism	Let-7b-5p in vesicles secreted by human airway cells reduces biofilm formation and increases antibiotic sensitivity of P. aeruginosa.	Koeppen K, Nymon A, Barnaby R, Bashor L, Li Z, Hampton TH, Liefeld AE, Kolling FW, LaCroix IS, Gerber SA, Hogan DA, Kasetty S, Nadell CD, Stanton BA.	Proc Natl Acad Sci U S A	10.1073/pnas.2105370118	2021
	High clinical impact of rapid susceptibility testing on CHROMID ESBL^® medium directly from swabs.	Romo-Ibanez A, Calatrava-Hernandez E, Gutierrez-Soto B, Perez-Ruiz M, Navarro-Mari JM, Gutierrez-Fernandez J.	Ann Transl Med	10.21037/atm.2020.02.158	2020
	Sequence heterogeneity of the PenA carbapenemase in clinical isolates of Burkholderia multivorans.	Becka SA, Zeiser ET, Marshall SH, Gatta JA, Nguyen K, Singh I, Greco C, Sutton GG, Fouts DE, LiPuma JJ, Papp-Wallace KM.	Diagn Microbiol Infect Dis	10.1016/j.diagmicrobio.2018.06.005	2018
	Destruction of Opportunistic Pathogens via Polymer Nanoparticle-Mediated Release of Plant-Based Antimicrobial Payloads.	Amato DN, Amato DV, Mavrodi OV, Braasch DA, Walley SE, Douglas JR, Mavrodi DV, Patton DL.	Adv Healthc Mater	10.1002/adhm.201500974	2016
Enzymology	Targeting Enterococcus faecalis HMG-CoA reductase with a non-statin inhibitor.	Bose S, Steussy CN, Lopez-Perez D, Schmidt T, Kulathunga SC, Seleem MN, Lipton M, Mesecar AD, Rodwell VW, Stauffacher CV.	Commun Biol	10.1038/s42003-023-04639-y	2023
	Complete genome dynamics of a dominant-lineage strain of Xanthomonas oryzae pv. oryzae harbouring a novel plasmid encoding a type IV secretion system.	Kaur A, Bansal K, Kumar S, Sonti RV, Patil PB.	Access Microbiol	10.1099/acmi.0.000063	2019
	Genomic adaptation of Burkholderia anthina to glyphosate uncovers a novel herbicide resistance mechanism.	Schwedt I, Collignon M, Mittelstadt C, Giudici F, Rapp J, Meissner J, Link H, Hertel R, Commichau FM.	Environ Microbiol Rep	10.1111/1758-2229.13184	2023
Pathogenicity	SAXS and stability studies of iron-induced oligomers of bacterial frataxin CyaY.	Fekry M, Alshokry W, Grela P, Tchorzewski M, Ahlgren EC, Soderberg CA, Gakh O, Isaya G, Al-Karadaghi S.	PLoS One	10.1371/journal.pone.0184961	2017
Metabolism	Analysis of human bronchial epithelial cell proinflammatory response to Burkholderia cenocepacia infection: inability to secrete il-1beta.	Gillette DD, Shah PA, Cremer T, Gavrilin MA, Besecker BY, Sarkar A, Knoell DL, Cormet-Boyaka E, Wewers MD, Butchar JP, Tridandapani S.	J Biol Chem	10.1074/jbc.c112.430298	2013
Metabolism	Burkholderia cepacia Complex Species Differ in the Frequency of Variation of the Lipopolysaccharide O-Antigen Expression During Cystic Fibrosis Chronic Respiratory Infection.	Hassan AA, Coutinho CP, Sa-Correia I.	Front Cell Infect Microbiol	10.3389/fcimb.2019.00273	2019
Metabolism	Burkholderia cenocepacia requires RpoE for growth under stress conditions and delay of phagolysosomal fusion in macrophages.	Flannagan RS, Valvano MA.	Microbiology (Reading)	10.1099/mic.0.2007/013714-0	2008
Enzymology	Investigation of Burkholderia cepacia complex in septicaemic patients in a tertiary care hospital, India.	Gautam V, Ray P, Puri GD, Sharma K, Vandamme P, Madhup SK, Das A, Malhotra P, Trehan A, Garg RK, Rana S, Koushal V, Kumar A.	Nepal Med Coll J		2009
	iTRAQ-Based Quantitative Proteomic Analysis of Acinetobacter baumannii under Hypoxia and Normoxia Reveals the Role of OmpW as a Virulence Factor.	Gil-Marques ML, Pachon J, Smani Y.	Microbiol Spectr	10.1128/spectrum.02328-21	2022
Enzymology	Comparison of the mechanism of antimicrobial action of the gold(I) compound auranofin in Gram-positive and Gram-negative bacteria.	Quadros Barse L, Ulfig A, Varatnitskaya M, Vazquez-Hernandez M, Yoo J, Imann AM, Lupilov N, Fischer M, Becker K, Bandow JE, Leichert LI.	Microbiol Spectr	10.1128/spectrum.00138-24	2024
Metabolism	A novel DSF-like signal from Burkholderia cenocepacia interferes with Candida albicans morphological transition.	Boon C, Deng Y, Wang LH, He Y, Xu JL, Fan Y, Pan SQ, Zhang LH.	ISME J	10.1038/ismej.2007.76	2008
	Cheating fosters species co-existence in well-mixed bacterial communities.	Leinweber A, Fredrik Inglis R, Kummerli R.	ISME J	10.1038/ismej.2016.195	2017
Pathogenicity	Antimicrobial Activity of Ibuprofen against Cystic Fibrosis-Associated Gram-Negative Pathogens.	Shah PN, Marshall-Batty KR, Smolen JA, Tagaev JA, Chen Q, Rodesney CA, Le HH, Gordon VD, Greenberg DE, Cannon CL.	Antimicrob Agents Chemother	10.1128/aac.01574-17	2018
	Burkholderia cenocepacia-induced delay of acidification and phagolysosomal fusion in cystic fibrosis transmembrane conductance regulator (CFTR)-defective macrophages.	Lamothe J, Valvano MA.	Microbiology (Reading)	10.1099/mic.0.2008/023200-0	2008
	Low frequency of community-acquired bacterial co-infection in patients hospitalized for COVID-19 based on clinical, radiological and microbiological criteria: a retrospective cohort study.	Coenen S, de la Court JR, Buis DTP, Meijboom LJ, Schade RP, Visser CE, van Hest R, Kuijvenhoven M, Prins JM, Nijman SFM, Sieswerda E, Sigaloff KCE.	Antimicrob Resist Infect Control	10.1186/s13756-021-01024-4	2021
Metabolism	CASP4/caspase-11 promotes autophagosome formation in response to bacterial infection.	Krause K, Caution K, Badr A, Hamilton K, Saleh A, Patel K, Seveau S, Hall-Stoodley L, Hegazi R, Zhang X, Gavrilin MA, Amer AO.	Autophagy	10.1080/15548627.2018.1491494	2018
	Blocking of Candida albicans biofilm formation by cis-2-dodecenoic acid and trans-2-dodecenoic acid.	Zhang Y, Cai C, Yang Y, Weng L, Wang L.	J Med Microbiol	10.1099/jmm.0.029058-0	2011
Genetics	The Hidden Genomic Diversity, Specialized Metabolite Capacity, and Revised Taxonomy of Burkholderia Sensu Lato.	Mullins AJ, Mahenthiralingam E.	Front Microbiol	10.3389/fmicb.2021.726847	2021
Metabolism	Characterization of a bifunctional catalase-peroxidase of Burkholderia cenocepacia.	Charalabous P, Risk JM, Jenkins R, Birss AJ, Hart CA, Smalley JW.	FEMS Immunol Med Microbiol	10.1111/j.1574-695x.2007.00224.x	2007
	Interactions Between Pathogenic Burkholderia and the Complement System: A Review of Potential Immune Evasion Mechanisms.	Syed I, Wooten RM.	Front Cell Infect Microbiol	10.3389/fcimb.2021.701362	2021
	Pan-kinome of Legionella expanded by a bioinformatics survey.	Krysinska M, Baranowski B, Deszcz B, Pawlowski K, Gradowski M.	Sci Rep	10.1038/s41598-022-26109-x	2022
	Iron acquisition strategies in pseudomonads: mechanisms, ecology, and evolution.	Kummerli R.	Biometals	10.1007/s10534-022-00480-8	2023
Genetics	Identification of Subunits for Novel Universal Vaccines against Three Predominant Serogroups and the Emerging O145 among Avian Pathogenic Escherichia coli by Pan-RV Pipeline.	Wang Z, Xu S, Zheng X, Zheng X, Liu M, Guo G, Yu Y, Han X, Liu Y, Wang K, Zhang W.	Appl Environ Microbiol	10.1128/aem.01061-22	2023
Pathogenicity	Genomic epidemiology of rifampicin ADP-ribosyltransferase (Arr) in the Bacteria domain.	Morgado S, Fonseca E, Vicente AC.	Sci Rep	10.1038/s41598-021-99255-3	2021
	Genetic similarity of Burkholderia cenocepacia from cystic fibrosis patients.	Pretto L, de-Paris F, Mombach Pinheiro Machado AB, Francisco Martins A, Barth AL.	Braz J Infect Dis	10.1016/j.bjid.2012.09.002	2013
	In-Frame and Unmarked Gene Deletions in Burkholderia cenocepacia via an Allelic Exchange System Compatible with Gateway Technology.	Fazli M, Harrison JJ, Gambino M, Givskov M, Tolker-Nielsen T.	Appl Environ Microbiol	10.1128/aem.03909-14	2015
	Penicillin Binding Protein from Pediococcus acidilactici Isolated from Nuruk for Food Biopreservative.	Song DH, Lee JM, Chung KH, An JH.	Iran J Public Health		2018
Metabolism	Proteomic identification and characterization of bacterial factors associated with Burkholderia cenocepacia survival in a murine host.	Chung JW, Speert DP.	Microbiology (Reading)	10.1099/mic.0.2006/000455-0	2007
	Approaches to measure the fitness of Burkholderia cepacia complex isolates.	Pope CF, Gillespie SH, Moore JE, McHugh TD.	J Med Microbiol	10.1099/jmm.0.017830-0	2010
	Dysregulated Calcium Homeostasis in Cystic Fibrosis Neutrophils Leads to Deficient Antimicrobial Responses.	Robledo-Avila FH, Ruiz-Rosado JD, Brockman KL, Kopp BT, Amer AO, McCoy K, Bakaletz LO, Partida-Sanchez S.	J Immunol	10.4049/jimmunol.1800076	2018
Enzymology	RecA gene sequence and Multilocus Sequence Typing for species-level resolution of Burkholderia cepacia complex isolates.	Cesarini S, Bevivino A, Tabacchioni S, Chiarini L, Dalmastri C.	Lett Appl Microbiol	10.1111/j.1472-765x.2009.02709.x	2009
	GATR-3, a Peptide That Eradicates Preformed Biofilms of Multidrug-Resistant Acinetobacter baumannii.	van Hoek ML, Alsaab FM, Carpenter AM.	Antibiotics (Basel)	10.3390/antibiotics13010039	2023
Phylogeny	SNaPBcen: a novel and practical tool for genotyping Burkholderia cenocepacia.	Eusebio N, Coutinho CP, Sa-Correia I, Araujo R.	J Clin Microbiol	10.1128/jcm.01019-13	2013
	Engineering of a Potent Recombinant Lectin-Toxin Fusion Protein to Eliminate Human Pluripotent Stem Cells.	Tateno H, Saito S.	Molecules	10.3390/molecules22071151	2017
Pathogenicity	Bactericidal efficacy of liposomal aminoglycosides against Burkholderia cenocepacia.	Halwani M, Mugabe C, Azghani AO, Lafrenie RM, Kumar A, Omri A.	J Antimicrob Chemother	10.1093/jac/dkm289	2007
Pathogenicity	Non-antibiotics, Efflux Pumps and Drug Resistance of Gram-negative Rods.	Laudy AE.	Pol J Microbiol	10.21307/pjm-2018-017	2018
	Competitive Fitness of Essential Gene Knockdowns Reveals a Broad-Spectrum Antibacterial Inhibitor of the Cell Division Protein FtsZ.	Hogan AM, Scoffone VC, Makarov V, Gislason AS, Tesfu H, Stietz MS, Brassinga AKC, Domaratzki M, Li X, Azzalin A, Biggiogera M, Riabova O, Monakhova N, Chiarelli LR, Riccardi G, Buroni S, Cardona ST.	Antimicrob Agents Chemother	10.1128/aac.01231-18	2018
	Methylomic correlates of autophagy activity in cystic fibrosis.	Caution K, Pan A, Krause K, Badr A, Hamilton K, Vaidya A, Gosu H, Daily K, Estfanous S, Gavrilin MA, Drew ME, Cormet-Boyaka E, Chen X, Frankhouser DE, Bundschuh R, Yan P, Dakhlallah D, Amer AO.	J Cyst Fibros	10.1016/j.jcf.2019.01.011	2019
Metabolism	Bioorthogonal non-canonical amino acid tagging reveals translationally active subpopulations of the cystic fibrosis lung microbiota.	Valentini TD, Lucas SK, Binder KA, Cameron LC, Motl JA, Dunitz JM, Hunter RC.	Nat Commun	10.1038/s41467-020-16163-2	2020
	The Response of Pseudomonas aeruginosa PAO1 Efflux Pump-Defective Mutants to N-Octanoyl-L-Homoserine Lactone.	Yawata Y, Maseda H, Okabe S, Ito A, Sawada I, Kurashima H, Uchiyama H, Nomura N.	Microbes Environ	10.1264/jsme2.me09130	2009
	SLC35A2 gene product modulates paramyxovirus fusion events during infection.	Yang Y, Wang Y, Campbell DE, Lee HW, Beatty W, Wang L, Baldridge M, Lopez CB.	PLoS Pathog	10.1371/journal.ppat.1012531	2025
Phylogeny	Deep Population Genomics Reveals Systematic and Parallel Evolution at a Lipopolysaccharide Biosynthetic Locus in Xanthomonas Pathogens That Infect Rice and Sugarcane.	Singh A, Bansal K, Kumar S, Patil PB.	Appl Environ Microbiol	10.1128/aem.00550-22	2022
Metabolism	Crystal structure of bacterial haem importer complex in the inward-facing conformation.	Naoe Y, Nakamura N, Doi A, Sawabe M, Nakamura H, Shiro Y, Sugimoto H.	Nat Commun	10.1038/ncomms13411	2016
	Structure of O-Antigen and Hybrid Biosynthetic Locus in Burkholderia cenocepacia Clonal Variants Recovered from a Cystic Fibrosis Patient.	Hassan AA, Maldonado RF, Dos Santos SC, Di Lorenzo F, Silipo A, Coutinho CP, Cooper VS, Molinaro A, Valvano MA, Sa-Correia I.	Front Microbiol	10.3389/fmicb.2017.01027	2017
Pathogenicity	The lipid A of Burkholderia multivorans C1576 smooth-type lipopolysaccharide and its pro-inflammatory activity in a cystic fibrosis airways model.	Ierano T, Cescutti P, Leone MR, Luciani A, Rizzo R, Raia V, Lanzetta R, Parrilli M, Maiuri L, Silipo A, Molinaro A.	Innate Immun	10.1177/1753425909347400	2010
	Investigation and Assessment for an effective approach to the reclamation of Polycyclic Aromatic Hydrocarbon (PAHs) contaminated site: SIN Bagnoli, Italy.	Guarino C, Zuzolo D, Marziano M, Conte B, Baiamonte G, Morra L, Benotti D, Gresia D, Stacul ER, Cicchella D, Sciarrillo R.	Sci Rep	10.1038/s41598-019-48005-7	2019
	SENCA: A Multilayered Codon Model to Study the Origins and Dynamics of Codon Usage.	Pouyet F, Bailly-Bechet M, Mouchiroud D, Gueguen L.	Genome Biol Evol	10.1093/gbe/evw165	2016
	Molecular Typing and Presence of Genetic Markers Among Strains of Banana Finger-Tip Rot Pathogen, Burkholderia cenocepacia, in Taiwan.	Lee YA, Chan CW.	Phytopathology	10.1094/phyto-97-2-0195	2007
	Burkholderia cepacia complex and limited cutaneous vasculitis in patients with cystic fibrosis: a case series.	Kayria M, Chris O, Dhasmana DJ, Nilesh M, Hodson ME, Khin G, Diana B, Simmonds NJ.	JRSM Open	10.1177/2054270417692732	2017
Metabolism	The DSF Family of Cell-Cell Signals: An Expanding Class of Bacterial Virulence Regulators.	Ryan RP, An SQ, Allan JH, McCarthy Y, Dow JM.	PLoS Pathog	10.1371/journal.ppat.1004986	2015
Pathogenicity	Evaluation of liquid and solid culture media for the recovery and enrichment of Burkholderia cenocepacia from distilled water.	Ahn Y, Kim JM, Ahn H, Lee YJ, LiPuma JJ, Hussong D, Cerniglia CE.	J Ind Microbiol Biotechnol	10.1007/s10295-014-1442-3	2014
	Infectious and Inflammatory Pathways to Cough.	Naqvi KF, Mazzone SB, Shiloh MU.	Annu Rev Physiol	10.1146/annurev-physiol-031422-092315	2023
Enzymology	Integrative transcriptome analysis revealed the pathogenic molecular basis of Rhizoctonia solani AG-3 TB at three progressive stages of infection.	Li X, An M, Xu C, Jiang L, Yan F, Yang Y, Zhang C, Wu Y.	Front Microbiol	10.3389/fmicb.2022.1001327	2022
	Metabolome Analysis of Constituents in Membrane Vesicles for Clostridium thermocellum Growth Stimulation.	Ichikawa S, Tsuge Y, Karita S.	Microorganisms	10.3390/microorganisms9030593	2021
	Diversity and distribution of Burkholderia cepacia complex in the rhizosphere of rice and maize.	Zhang L, Xie G.	FEMS Microbiol Lett	10.1111/j.1574-6968.2006.00530.x	2007
	Consequences of CRISPR-Cas9-Mediated CFTR Knockout in Human Macrophages.	Zhang S, Shrestha CL, Wisniewski BL, Pham H, Hou X, Li W, Dong Y, Kopp BT.	Front Immunol	10.3389/fimmu.2020.01871	2020
	Pilus-mediated epithelial cell death in response to infection with Burkholderia cenocepacia.	Cheung KJ, Li G, Urban TA, Goldberg JB, Griffith A, Lu F, Burns JL.	Microbes Infect	10.1016/j.micinf.2007.03.001	2007
	The Cell-Cell Communication Signal Indole Controls the Physiology and Interspecies Communication of Acinetobacter baumannii.	Cui B, Chen X, Guo Q, Song S, Wang M, Liu J, Deng Y.	Microbiol Spectr	10.1128/spectrum.01027-22	2022
	Altered Degranulation and pH of Neutrophil Phagosomes Impacts Antimicrobial Efficiency in Cystic Fibrosis.	Hayes E, Murphy MP, Pohl K, Browne N, McQuillan K, Saw LE, Foley C, Gargoum F, McElvaney OJ, Hawkins P, Gunaratnam C, McElvaney NG, Reeves EP.	Front Immunol	10.3389/fimmu.2020.600033	2020
	Promoter Architecture Differences among Alphaproteobacteria and Other Bacterial Taxa.	Myers KS, Noguera DR, Donohue TJ.	mSystems	10.1128/msystems.00526-21	2021
Metabolism	The pyrin inflammasome in host-microbe interactions.	Loeven NA, Medici NP, Bliska JB.	Curr Opin Microbiol	10.1016/j.mib.2020.01.005	2020
	Elongation factor P modulates Acinetobacter baumannii physiology and virulence as a cyclic dimeric guanosine monophosphate effector.	Guo Q, Cui B, Wang M, Li X, Tan H, Song S, Zhou J, Zhang LH, Deng Y.	Proc Natl Acad Sci U S A	10.1073/pnas.2209838119	2022
Metabolism	The Role of Reactive Oxygen Species in Antibiotic-Induced Cell Death in Burkholderia cepacia Complex Bacteria.	Van Acker H, Gielis J, Acke M, Cools F, Cos P, Coenye T.	PLoS One	10.1371/journal.pone.0159837	2016
Phenotype	Phenotypic diversity and genotypic flexibility of Burkholderia cenocepacia during long-term chronic infection of cystic fibrosis lungs.	Lee AH, Flibotte S, Sinha S, Paiero A, Ehrlich RL, Balashov S, Ehrlich GD, Zlosnik JE, Mell JC, Nislow C.	Genome Res	10.1101/gr.213363.116	2017
	Cell Wall Recycling-Linked Coregulation of AmpC and PenB beta-Lactamases through ampD Mutations in Burkholderia cenocepacia.	Hwang J, Kim HS.	Antimicrob Agents Chemother	10.1128/aac.01068-15	2015
	Improved cultural selectivity of medically significant fungi by suppression of contaminating bacterial flora employing gallium (III) nitrate.	Moore JE, Murphy A, Millar BC, Loughrey A, Rooney PJ, Elborn JS, Goldsmith CE.	J Microbiol Methods	10.1016/j.mimet.2008.09.018	2009
Pathogenicity	Bacterial Quorum-Sensing Signal DSF Inhibits LPS-Induced Inflammations by Suppressing Toll-like Receptor Signaling and Preventing Lysosome-Mediated Apoptosis in Zebrafish.	Zhu H, Wang Z, Wang W, Lu Y, He YW, Tian J.	Int J Mol Sci	10.3390/ijms23137110	2022
	Nebuliser cleaning and disinfection practice in the home among patients with cystic fibrosis.	MacFarlane M, Carson L, Crossan A, Bell J, Moore JE, Millar BC.	J Infect Prev	10.1177/1757177419855603	2020
Metabolism	Engineering acyl-homoserine lactone-interfering enzymes toward bacterial control.	Billot R, Plener L, Jacquet P, Elias M, Chabriere E, Daude D.	J Biol Chem	10.1074/jbc.rev120.013531	2020
Genetics	Exploring the comparative genome of rice pathogen Burkholderia plantarii: unveiling virulence, fitness traits, and a potential type III secretion system effector.	Mannaa M, Lee D, Lee HH, Han G, Kang M, Kim TJ, Park J, Seo YS.	Front Plant Sci	10.3389/fpls.2024.1416253	2024
	Enhanced C-To-T and A-To-G Base Editing in Mitochondrial DNA with Engineered DdCBE and TALED.	Wei Y, Jin M, Huang S, Yao F, Ren N, Xu K, Li S, Gao P, Zhou Y, Chen Y, Yang H, Li W, Xu C, Zhang M, Wang X.	Adv Sci (Weinh)	10.1002/advs.202304113	2024
Metabolism	Vitamin E Increases Antimicrobial Sensitivity by Inhibiting Bacterial Lipocalin Antibiotic Binding.	Naguib MM, Valvano MA.	mSphere	10.1128/msphere.00564-18	2018
	Multistate outbreak of Burkholderia cenocepacia colonization and infection associated with the use of intrinsically contaminated alcohol-free mouthwash.	Kutty PK, Moody B, Gullion JS, Zervos M, Ajluni M, Washburn R, Sanderson R, Kainer MA, Powell TA, Clarke CF, Powell RJ, Pascoe N, Shams A, LiPuma JJ, Jensen B, Noble-Wang J, Arduino MJ, McDonald LC.	Chest	10.1378/chest.07-1545	2007
	Intracellular survival of Burkholderia cenocepacia in macrophages is associated with a delay in the maturation of bacteria-containing vacuoles.	Lamothe J, Huynh KK, Grinstein S, Valvano MA.	Cell Microbiol	10.1111/j.1462-5822.2006.00766.x	2007
	Invasion and biofilm formation of Burkholderia dolosa is comparable with Burkholderia cenocepacia and Burkholderia multivorans.	Caraher E, Duff C, Mullen T, Mc Keon S, Murphy P, Callaghan M, McClean S.	J Cyst Fibros	10.1016/j.jcf.2006.05.007	2007
Metabolism	Structural basis for mannose recognition by a lectin from opportunistic bacteria Burkholderia cenocepacia.	Lameignere E, Malinovska L, Slavikova M, Duchaud E, Mitchell EP, Varrot A, Sedo O, Imberty A, Wimmerova M.	Biochem J	10.1042/bj20071276	2008
Phylogeny	Lung transplantation for patients with cystic fibrosis and Burkholderia cepacia complex infection: a single-center experience.	De Soyza A, Meachery G, Hester KL, Nicholson A, Parry G, Tocewicz K, Pillay T, Clark S, Lordan JL, Schueler S, Fisher AJ, Dark JH, Gould FK, Corris PA.	J Heart Lung Transplant	10.1016/j.healun.2010.06.007	2010
Phenotype	Environmental Burkholderia cenocepacia Strain Enhances Fitness by Serial Passages during Long-Term Chronic Airways Infection in Mice.	Bragonzi A, Paroni M, Pirone L, Coladarci I, Ascenzioni F, Bevivino A	Int J Mol Sci	10.3390/ijms18112417	2017
Pathogenicity	Optimization and characterization of a murine lung infection model for the evaluation of novel therapeutics against Burkholderia cenocepacia.	Vanhoutte B, Cappoen D, Maira BM, Cools F, Torfs E, Coenye T, Martinet W, Caljon G, Maes L, Delputte P, Cos P	J Microbiol Methods	10.1016/j.mimet.2017.06.003	2017
Pathogenicity	Interaction of environmental Burkholderia cenocepacia strains with cystic fibrosis and non-cystic fibrosis bronchial epithelial cells in vitro.	Bevivino A, Pirone L, Pilkington R, Cifani N, Dalmastri C, Callaghan M, Ascenzioni F, McClean S	Microbiology (Reading)	10.1099/mic.0.056986-0	2012
Metabolism	Characterization of liposomes formed by lipopolysaccharides from Burkholderia cenocepacia, Burkholderia multivorans and Agrobacterium tumefaciens: from the molecular structure to the aggregate architecture.	D'Errico G, Silipo A, Mangiapia G, Vitiello G, Radulescu A, Molinaro A, Lanzetta R, Paduano L	Phys Chem Chem Phys	10.1039/c0cp00066c	2010
Pathogenicity	The complete structure and pro-inflammatory activity of the lipooligosaccharide of the highly epidemic and virulent gram-negative bacterium Burkholderia cenocepacia ET-12 (strain J2315).	Silipo A, Molinaro A, Ierano T, De Soyza A, Sturiale L, Garozzo D, Aldridge C, Corris PA, Khan CM, Lanzetta R, Parrilli M	Chemistry	10.1002/chem.200601406	2007
Genetics	Use of ribosomal promoters from Burkholderia cenocepacia and Burkholderia cepacia for improved expression of transporter protein in Escherichia coli.	Yu M, Tsang JS	Protein Expr Purif	10.1016/j.pep.2006.04.004	2006
	Burkholderia semiarida sp. nov. and Burkholderia sola sp. nov., two novel B. cepacia complex species causing onion sour skin.	Velez LS, Aburjaile FF, Farias ARG, Baia ADB, Oliveira WJ, Silva AMF, Benko-Iseppon AM, Azevedo V, Brenig B, Ham JH, Souza EB, Gama MAS.	Syst Appl Microbiol	10.1016/j.syapm.2023.126415	2023
	Burkholderia orbicola sp. nov., a novel species within the Burkholderia cepacia complex.	Morales-Ruiz LM, Rodriguez-Cisneros M, Kerber-Diaz JC, Rojas-Rojas FU, Ibarra JA, Estrada-de Los Santos P.	Arch Microbiol	10.1007/s00203-022-02778-0	2022
	Pseudomonas halotolerans sp. nov., a halotolerant biocontrol agent with plant-growth properties	Sanchez P, Castillo I, Martinez-Checa F, Sampedro I, Llamas I.	Front Plant Sci		2025
Biotechnology	Taxonomy-guided selection of Paraburkholderia busanensis sp. nov.: a versatile biocontrol agent with mycophagy against Colletotrichum scovillei causing pepper anthracnose.	Mannaa M, Han G, Jeong T, Kang M, Lee D, Jung H, Seo Y-S.	Microbiol Spectr	10.1128/spectrum.02426-23	2023
Phylogeny	Burkholderia cenocepacia sp. nov.--a new twist to an old story.	Vandamme P, Holmes B, Coenye T, Goris J, Mahenthiralingam E, LiPuma JJ, Govan JR	Res Microbiol	10.1016/S0923-2508(03)00026-3	2003

References

#6505	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 16553
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#37374	; Curators of the CIP;
#58156	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 48434
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#68369	Automatically annotated from API 20NE .
#68382	Automatically annotated from API zym .
#117244	Collection of Institut Pasteur ; Curators of the CIP; CIP 108255
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Burkholderia cenocepacia (CIP 108255, DSM 16553, ATCC BAA-245)

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