Streptomyces thioluteus (DSM 40027, ATCC 12310, CBS 642.72)

Name: Streptomyces thioluteus (DSM 40027, ATCC 12310, CBS 642.72)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 16173

Type strain

Strain Designation 26-A

Culture col. no. DSM 40027 ATCC 12310 CBS 642.72 DSM 41486 IFO 13341 18 more

NCBI tax ID(s) 66431

Special Collections DSMZ JCM CIP Wink compendium

History <- E.B. Shirling, ISP <- Y. Okami, NIHJ KCC S-0087 <-- H. Yonehara <-- Y. Okami 26-A. KCC S-0182 <-- M. Mayama <-- Y. Okami Z-6-25. CIP <- 2003, JCM <- 1983, KCC <- IFO <- SAJ <- ISP <- Y. Okami: strain 26-A

Links

Streptomyces thioluteus 26-A is an obligate aerobe, Gram-positive, filament-shaped bacterium of the family Streptomycetaceae.

Gram-positive filament-shaped obligate aerobe genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 45509

ATCC 12310,IFO 3364,JCM 4087,JCM 4182,DSM 40027,DSM 41486,IFO 13341,CCRC 12428,HUT 6071,NRRL B-1667,JCM 4844,VKM Ac-1914,CBS 642.72,NBRC 13341,NBRC 3364,LMG 20253,BCRC 12428,CIP 108140,CGMCC 4.1930

@ref 20215

Last LPSN update 2026-02-09 11:21:54

Domain Bacteria

Phylum Actinomycetota

Class Actinomycetes

Order Kitasatosporales

Family Streptomycetaceae

Genus Streptomyces

Species Streptomyces thioluteus

Full scientific name Streptomyces thioluteus (Okami 1952) Witt and Stackebrandt 1991

Synonyms (2)

"Streptomyces thioluteus"
Streptoverticillium thioluteum

BacDive ID	Other strains from **Streptomyces thioluteus** (1)	Type strain
105502	S. thioluteus STI40354(IMET), ChinaA-101, IMET 40354

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Motility
123523	positive	filament-shaped

Colony morphology

123523

Hemolysis ability1

Multimedia

@ref:	9226
multimedia content:	DSM_40027.jpg
multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_40027.jpg
caption:	Medium 65 28°C
intellectual property rights:	© Leibniz-Institut DSMZ
manual_annotation:	1

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
9226	GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)	Medium recipe at MediaDive	Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water
37414	MEDIUM 57 - for Streptomyces, Nocardioides, Lentzea albidocapillata and Streptoverticillium reticulum		Distilled water make up to (1000.000 ml);Agar (15.000 g);Glucose (4.000g);Yeast extract (4.000 g);Malt extract (10.000 g);Calcium carbonate (2.000 g)
9226	ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84)	Medium recipe at MediaDive	Name: ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84) Composition: Agar 20.0 g/l Rolled oats 20.0 g/l ZnSO4 x 7 H2O 0.001 g/l MnCl2 x 4 H2O 0.001 g/l FeSO4 x 7 H2O 0.001 g/l Distilled water
123523	CIP Medium 57	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
9226	positive	growth	28
18466	positive	optimum	28
37414	positive	growth	30
67770	positive	growth	28
123523	positive	growth	25-37
123523	negative	growth	10
123523	negative	growth	41
123523	negative	growth	45

Physiology and metabolism

Oxygen tolerance

123523

Oxygen toleranceobligate aerobe

Compound production

@ref	Compound
9226	aureothin
9226	aureothricin

Halophily

@ref	Salt	Growth	Tested relation	Concentration
18466	NaCl	positive	maximum	2.5 %
123523	NaCl	positive	growth	0-2 %
123523	NaCl		growth	4 %
123523	NaCl		growth	6 %
123523	NaCl		growth	8 %
123523	NaCl		growth	10 %

Tolerance

@ref	Compound	Percentage
18466	Lysozyme	1

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68368	29016 ChEBI	arginine	+	hydrolysis	from API 20E
123523	16947 ChEBI	citrate	-	carbon source
68368	16947 ChEBI	citrate	+	assimilation	from API 20E
123523	4853 ChEBI	esculin	+	hydrolysis
68368	5291 ChEBI	gelatin	+	hydrolysis	from API 20E
123523	606565 ChEBI	hippurate	+	hydrolysis
68368	25094 ChEBI	lysine	+	degradation	from API 20E
123523	17632 ChEBI	nitrate	-	reduction
123523	17632 ChEBI	nitrate	-	respiration
123523	16301 ChEBI	nitrite	-	reduction
68368	18257 ChEBI	ornithine	+	degradation	from API 20E
68368	27897 ChEBI	tryptophan	-	energy source	from API 20E
68368	16199 ChEBI	urea	+	hydrolysis	from API 20E

Antibiotic resistance

@ref	Metabolite	Is sensitive	Is resistant
123523	0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)

Metabolite production

@ref	Chebi-ID	Metabolite
68368	15688 ChEBI	acetoin	from API 20E
67770	156452 ChEBI	aureothricin
68368	16136 ChEBI	hydrogen sulfide	from API 20E
123523	35581 ChEBI	indole
68368	35581 ChEBI	indole	from API 20E
67770	156450 ChEBI	thiolutin

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Methylred-test	Indole test
123523	15688 ChEBI	acetoin	-
68368	15688 ChEBI	acetoin	+			from API 20E
123523	17234 ChEBI	glucose		-
68368	35581 ChEBI	indole			-	from API 20E

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
123523	alcohol dehydrogenase	-	1.1.1.1
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68382	alpha-chymotrypsin	+	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68382	alpha-mannosidase	+	3.2.1.24	from API zym
123523	amylase	-
68368	arginine dihydrolase	+	3.5.3.6	from API 20E
68382	beta-galactosidase	-	3.2.1.23	from API zym
123523	beta-galactosidase	+	3.2.1.23
68368	beta-galactosidase	+	3.2.1.23	from API 20E
68382	beta-glucosidase	-	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
123523	caseinase	+	3.4.21.50
123523	catalase	+	1.11.1.6
68382	cystine arylamidase	+	3.4.11.3	from API zym
123523	DNase	+
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
123523	gamma-glutamyltransferase	+	2.3.2.2
123523	gelatinase	+
68368	gelatinase	+		from API 20E
123523	lecithinase	+
68382	leucine arylamidase	+	3.4.11.1	from API zym
123523	lipase	-
68382	lipase (C 14)	+		from API zym
123523	lysine decarboxylase	-	4.1.1.18
68368	lysine decarboxylase	+	4.1.1.18	from API 20E
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
123523	ornithine decarboxylase	-	4.1.1.17
68368	ornithine decarboxylase	+	4.1.1.17	from API 20E
123523	oxidase	-
123523	phenylalanine ammonia-lyase	-	4.3.1.24
123523	protease	+
68382	trypsin	-	3.4.21.4	from API zym
123523	tryptophan deaminase	-
68368	tryptophan deaminase	-	4.1.99.1	from API 20E
123523	tween esterase	-
123523	urease	+	3.5.1.5
68368	urease	+	3.5.1.5	from API 20E
68382	valine arylamidase	+		from API zym

API 20E

@ref	ONPG	ADH (Arg)	LDC (Lys)	ODC	CIT	H2S productionH2S	URE	TDA (Trp)	IND	Acetoin production (Voges Proskauer test)VP	GEL	GLU	MAN	INO	Sor	RHA	SAC	MEL	AMY	ARA	OX	Nitrite productionNO2	Reduction to N2N2	MotilityMOB	Growth on MacConkey mediumMAC	OF-O	OF-F
18466	+	+	+	+	+	-	+	-	-	+	+	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
123523	-	+	+	+	+	+	+	+	-	+	+	+	-	-	-	+	-	-	+	-

API biotype100

@ref	ControlQ	D-glucose as carbon sourceGLU	D-fructose as carbon sourceFRU	D-galactose as carbon sourceGAL	D-trehalose as carbon sourceTRE	D-mannose as carbon sourceMNE	L-sorbose as carbon sourceSBE	D-melibiose as carbon sourceMEL	sucrose as carbon sourceSAC	D-raffinose as carbon sourceRAF	maltotriose as carbon sourceMTE	maltose as carbon sourceMAL	lactose as carbon sourceLAC	lactulose as carbon sourceLTE	1-O-methyl-beta-galactopyranoside as carbon sourceMbGa	1-O-methyl-alpha-galactopyranoside as carbon sourceMaGa	D-cellobiose as carbon sourceCEL	gentiobiose as carbon sourceGEN	1-O-methyl-beta-D-glucopyranoside as carbon sourceMbGu	esculin as carbon sourceESC	D-ribose as carbon sourceRIB	L-arabinose as carbon sourceARA	D-xylose as carbon sourceXYL	palatinose as carbon sourcePLE	L-rhamnose as carbon sourceRHA	L-fucose as carbon sourceFUC	D-melezitose as carbon sourceMLZ	D-arabitol as carbon sourceDARL	L-arabitol as carbon sourceLARL	xylitol as carbon sourceXLT	dulcitol as carbon sourceDUL	D-tagatose as carbon sourceTAG	glycerol as carbon sourceGLY	myo-inositol as carbon sourceINO	D-mannitol as carbon sourceMAN	maltitol as carbon sourceMTL	D-turanose as carbon sourceTUR	D-sorbitol as carbon sourceSOR	adonitol as carbon sourceADO	hydroxyquinoline-beta-glucuronide as carbon sourceHBG	D-lyxose as carbon sourceLYX	i-erythritol as carbon sourceERY	1-O-methyl-alpha-D-glucoside as carbon sourceMDG	3-O-methyl-D-glucose as carbon source3MDG	D-saccharate as carbon sourceSAT	mucate as carbon sourceMUC	L-tartrate as carbon sourceLTAT	D-tartrate as carbon sourceDTAT	meso-tartrate as carbon sourceMTAT	D-malate as carbon sourceDMLT	L-malate as carbon sourceLMLT	cis-aconitate as carbon sourceCATE	trans-aconitate as carbon sourceTATE	tricarballylate as carbon sourceTTE	citrate as carbon sourceCIT	D-glucuronate as carbon sourceGRT	D-galacturonate as carbon sourceGAT	2-ketogluconate as carbon source2KG	5-ketogluconate as carbon source5KG	tryptophan as carbon sourceTRY	N-acetyl-D-glucosamine as carbon sourceNAG	D-gluconate as carbon sourceGNT	phenylacetate as carbon sourcePAC	protocatechuate as carbon sourcePAT	4-hydroxybenzoate as carbon sourcepOBE	quinate as carbon sourceQAT	gentisate as carbon sourceGTE	3-hydroxybenzoate as carbon sourcemOBE	benzoate as carbon sourceBAT	3-phenylpropionate as carbon sourcePPAT	m-coumarate as carbon sourceCMT	trigonelline as carbon sourceTGE	betaine as carbon sourceBET	putrescine as carbon sourcePCE	4-aminobutyrate as carbon sourceABT	histamine as carbon sourceHIN	DL-lactate as carbon sourceLAT	caprate as carbon sourceCAP	caprylate as carbon sourceCYT	L-histidine as carbon sourceHIS	succinate as carbon sourceSUC	fumarate as carbon sourceFUM	glutarate as carbon sourceGRE	DL-glycerate as carbon sourceGYT	5-aminovalerate as carbon sourceAVT	ethanolamine as carbon sourceETN	tryptamine as carbon sourceTTN	D-glucosamine as carbon sourceGLN	itaconate as carbon sourceITA	3-hydroxybutyrate as carbon source3OBU	L-aspartate as carbon sourceAPT	L-glutamate as carbon sourceGTT	L-proline as carbon sourcePRO	D-alanine as carbon sourceDALA	L-alanine as carbon sourceLALA	L-serine as carbon sourceSER	malonate as carbon sourceMNT	propionate as carbon sourcePROP	L-tyrosine as carbon sourceTYR	2-ketoglutarate as carbon source2KT
123523	not determinedn.d.	+	-	-	-	+	-	-	-	-	+	+	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	+	-	-	-	-	-	-	-	-	-	-	-	+	+	-	-	-	+	-	-	-	-	-	-	+	-	+	-	+	+	+	+	-	+	+	-	-	+	-

Isolation, sampling and environmental information

Isolation

@ref	Sample type	Geographic location	Country	Country ISO 3 Code	Continent
37414			Japan	JPN	Asia
67770	Soil	Mitaka City, near Tokyo	Japan	JPN	Asia
123523	Environment, Soil		Japan	JPN	Asia

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
9226	1	Risk group (German classification) According to TRBA 466
18466	1	German classification According to TRBA 466
123523	1	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	NCBI tax ID
124043	ASM3953586v1 assembly for Streptomyces thioluteus JCM 4087	contig	GCA_039535865	66431

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Streptomyces thioluteus strain IFO 13341 16S ribosomal RNA gene, partial sequence	AY999848	1419	66431
20218	Streptomyces thioluteus gene for 16S ribosomal RNA, partial sequence, strain: JCM 4087	D44001	120	66431
20218	Streptomyces thioluteus 16S rRNA gene, type strain LMG 20253	AJ781360	1476	66431
20218	Streptomyces thioluteus gene for 16S rRNA, partial sequence, strain: NBRC 13341	AB184344	1479	66431
20218	Streptomyces thioluteus gene for 16S rRNA, partial sequence, strain: NBRC 3364	AB184753	1467	66431
124043	Streptomyces thioluteus strain JCM 4087 16S ribosomal RNA gene, partial sequence.	MT760480	1324	66431

Genome-based predictions

Literature

Topic	Title	Authors	Journal	DOI	Year
	Copper-chelating natural products.	Manley OM, Rosenzweig AC.	J Biol Inorg Chem	10.1007/s00775-025-02099-9	2025
	Screening of natural phenazine producers for electroactivity in bioelectrochemical systems.	Franco A, Elbahnasy M, Rosenbaum MA.	Microb Biotechnol	10.1111/1751-7915.14199	2023
	Construction and engineering of large biochemical pathways via DNA assembler.	Shao Z, Zhao H.	Methods Mol Biol	10.1007/978-1-62703-625-2_9	2013
	Metabolic engineering of Escherichia coli for 4-nitrophenylalanine production via the 4-aminophenylalanine synthetic pathway.	Mori A, Hirata Y, Kishida M, Nonaka D, Kondo A, Mori Y, Noda S, Tanaka T.	Metab Eng	10.1016/j.ymben.2025.04.006	2025
	p-Nitrobenzoate production from glucose by utilizing p-aminobenzoate N-oxygenase: AurF.	Mori A, Hirata Y, Kishida M, Mori Y, Kondo A, Noda S, Tanaka T.	Enzyme Microb Technol	10.1016/j.enzmictec.2023.110321	2023
	Isolation of two new stereochemical variants of streptophenazine by cocultivation of Streptomyces NIIST-D31, Streptomyces NIIST-D47, and Streptomyces NIIST-D63 strains in ³C₂ combinations.	Induja DK, Jesmina ARS, Joseph MM, Shamjith S, Ingaladal N, Maiti KK, Kumar BSD, Lankalapalli RS.	J Antibiot (Tokyo)	10.1038/s41429-023-00638-7	2023
Metabolism	Repurposing the 3-Isocyanobutanoic Acid Adenylation Enzyme SfaB for Versatile Amidation and Thioesterification.	Zhu M, Wang L, He J.	Angew Chem Int Ed Engl	10.1002/anie.202010042	2021
Pathogenicity	Diisonitrile-Mediated Reactive Oxygen Species Accumulation Leads to Bacterial Growth Inhibition.	Zhu M, Wang L, Zhang W, Liu Z, Ali M, Imtiaz M, He J.	J Nat Prod	10.1021/acs.jnatprod.0c00125	2020
	Tandem Hydration of Diisonitriles Triggered by Isonitrile Hydratase in Streptomyces thioluteus.	Zhu M, Wang L, Zhang Q, Ali M, Zhu S, Yu P, Gu X, Zhang H, Zhu Y, He J.	Org Lett	10.1021/acs.orglett.8b01341	2018
	Natural products with gamma-pyrone scaffold from Streptomyces.	Magar RT, Sohng JK.	Appl Microbiol Biotechnol	10.1007/s00253-024-13296-y	2024
Metabolism	Chemical Diversification Based on Substrate Promiscuity of a Standalone Adenylation Domain in a Reconstituted NRPS System.	Zhu M, Wang L, He J.	ACS Chem Biol	10.1021/acschembio.8b00938	2019
Metabolism	Diisonitrile Natural Product SF2768 Functions As a Chalkophore That Mediates Copper Acquisition in Streptomyces thioluteus.	Wang L, Zhu M, Zhang Q, Zhang X, Yang P, Liu Z, Deng Y, Zhu Y, Huang X, Han L, Li S, He J.	ACS Chem Biol	10.1021/acschembio.7b00897	2017
	Methodology for awakening the potential secondary metabolic capacity in actinomycetes.	Saito S, Arai MA.	Beilstein J Org Chem	10.3762/bjoc.20.69	2024
	Repurposing Iron- and 2-Oxoglutarate-Dependent Oxygenases to Catalyze Olefin Hydration.	Wang B, Lu Y, Cha L, Chen TY, Palacios PM, Li L, Guo Y, Chang WC, Chen C.	Angew Chem Int Ed Engl	10.1002/anie.202311099	2023
	Isocyanides inhibit bacterial pathogens by covalent targeting of essential metabolic enzymes.	Geissler A, Junca H, Kany AM, Daumann LJ, Hirsch AKH, Pieper DH, Sieber SA.	Chem Sci	10.1039/d4sc01940g	2024
	Distribution and diversity of dimetal-carboxylate halogenases in cyanobacteria.	Eusebio N, Rego A, Glasser NR, Castelo-Branco R, Balskus EP, Leao PN.	BMC Genomics	10.1186/s12864-021-07939-x	2021
Genetics	Strategies Used for the Discovery of New Microbial Metabolites with Antibiotic Activity.	Dasi-Delgado P, Andreu C, Del Olmo ML.	Molecules	10.3390/molecules30132868	2025
Metabolism	Highly selective but multifunctional oxygenases in secondary metabolism.	Cochrane RV, Vederas JC.	Acc Chem Res	10.1021/ar500242c	2014
	Proteomics fingerprinting reveals importance of iron and oxidative stress in Streptomyces scabies-Solanum tuberosum interactions.	Giroux L, Isayenka I, Lerat S, Beaudoin N, Beaulieu C.	Front Microbiol	10.3389/fmicb.2024.1466927	2024
	Halogenated Metal-Binding Compounds from Shipworm Symbionts.	Miller BW, Schmidt EW, Concepcion GP, Haygood MG.	J Nat Prod	10.1021/acs.jnatprod.1c01049	2022
Metabolism	Dual-purpose isocyanides produced by Aspergillus fumigatus contribute to cellular copper sufficiency and exhibit antimicrobial activity.	Raffa N, Won TH, Sukowaty A, Candor K, Cui C, Halder S, Dai M, Landero-Figueroa JA, Schroeder FC, Keller NP.	Proc Natl Acad Sci U S A	10.1073/pnas.2015224118	2021
	Diisonitrile Lipopeptides Mediate Resistance to Copper Starvation in Pathogenic Mycobacteria.	Buglino JA, Ozakman Y, Xu Y, Chowdhury F, Tan DS, Glickman MS.	mBio	10.1128/mbio.02513-22	2022
Metabolism	Structural and biochemical basis for the firm chemo- and regioselectivity of the nitro-forming N-oxygenase AurF.	Fries A, Winkler R, Hertweck C.	Chem Commun (Camb)	10.1039/c0cc02811h	2010
	Programmed Iteration Controls the Assembly of the Nonanoic Acid Side Chain of the Antibiotic Mupirocin.	Winter AJ, Rowe MT, Weir ANM, Akter N, Mbatha SZ, Walker PD, Williams C, Song Z, Race PR, Willis CL, Crump MP.	Angew Chem Weinheim Bergstr Ger	10.1002/ange.202212393	2022
Enzymology	Characterization of a non-ribosomal peptide synthetase-associated diiron arylamine N-oxygenase from Pseudomonas syringae pv. phaseolicola.	Platter E, Lawson M, Marsh C, Sazinsky MH.	Arch Biochem Biophys	10.1016/j.abb.2011.01.010	2011
	Identification and enhancing production of a novel macrolide compound in engineered Streptomyces peucetius.	Pham VTT, Nguyen HT, Nguyen CT, Choi YS, Dhakal D, Kim TS, Jung HJ, Yamaguchi T, Sohng JK.	RSC Adv	10.1039/d0ra06099b	2021
Enzymology	AurF from Streptomyces thioluteus and a possible new family of manganese/iron oxygenases.	Krebs C, Matthews ML, Jiang W, Bollinger JM.	Biochemistry	10.1021/bi701060g	2007
	Novel Sources of Biodiversity and Biomolecules from Bacteria Isolated from a High Middle Ages Soil Sample in Palermo (Sicily, Italy).	Vassallo A, Modi A, Quagliariello A, Bacci G, Faddetta T, Gallo M, Provenzano A, La Barbera A, Lombardo G, Maggini V, Firenzuoli F, Zaccaroni M, Gallo G, Caramelli D, Aleo Nero C, Baldi F, Fani R, Palumbo Piccionello A, Pucciarelli S, Puglia AM, Sineo L.	Microbiol Spectr	10.1128/spectrum.04374-22	2023
Metabolism	Structure and action of the N-oxygenase AurF from Streptomyces thioluteus.	Zocher G, Winkler R, Hertweck C, Schulz GE.	J Mol Biol	10.1016/j.jmb.2007.06.014	2007
	Characterization of the positive SARP family regulator PieR for improving piericidin A1 production in Streptomyces piomogeues var. Hangzhouwanensis.	Li Y, Kong L, Shen J, Wang Q, Liu Q, Yang W, Deng Z, You D.	Synth Syst Biotechnol	10.1016/j.synbio.2018.12.002	2019
Metabolism	Identification and characterization of a novel hydroxylamine oxidase, DnfA, that catalyzes the oxidation of hydroxylamine to N₂.	Wu MR, Miao LL, Liu Y, Qian XX, Hou TT, Ai GM, Yu L, Ma L, Gao XY, Qin YL, Zhu HZ, Du L, Li SY, Tian CL, Li DF, Liu ZP, Liu SJ.	J Biol Chem	10.1016/j.jbc.2022.102372	2022
Metabolism	Non-colinear polyketide biosynthesis in the aureothin and neoaureothin pathways: an evolutionary perspective.	Traitcheva N, Jenke-Kodama H, He J, Dittmann E, Hertweck C.	Chembiochem	10.1002/cbic.200700309	2007
Metabolism	Four-electron oxidation of p-hydroxylaminobenzoate to p-nitrobenzoate by a peroxodiferric complex in AurF from Streptomyces thioluteus.	Li N, Korboukh VK, Krebs C, Bollinger JM.	Proc Natl Acad Sci U S A	10.1073/pnas.1002785107	2010
Enzymology	A long-lived, substrate-hydroxylating peroxodiiron(III/III) intermediate in the amine oxygenase, AurF, from Streptomyces thioluteus.	Korboukh VK, Li N, Barr EW, Bollinger JM, Krebs C.	J Am Chem Soc	10.1021/ja9064969	2009
Metabolism	Formation of the aureothin tetrahydrofuran ring by a bifunctional cytochrome p450 monooxygenase.	He J, Muller M, Hertweck C.	J Am Chem Soc	10.1021/ja046104h	2004
Metabolism	Biosynthetic origin of the rare nitroaryl moiety of the polyketide antibiotic aureothin: involvement of an unprecedented N-oxygenase.	He J, Hertweck C.	J Am Chem Soc	10.1021/ja039328t	2004
Metabolism	A Role for Mycobacterium tuberculosis Sigma Factor C in Copper Nutritional Immunity.	Grosse-Siestrup BT, Gupta T, Helms S, Tucker SL, Voskuil MI, Quinn FD, Karls RK.	Int J Mol Sci	10.3390/ijms22042118	2021
Metabolism	Exploiting enzymatic promiscuity to engineer a focused library of highly selective antifungal and antiproliferative aureothin analogues.	Werneburg M, Busch B, He J, Richter ME, Xiang L, Moore BS, Roth M, Dahse HM, Hertweck C.	J Am Chem Soc	10.1021/ja102751h	2010
Metabolism	Diiron monooxygenases in natural product biosynthesis.	Komor AJ, Jasniewski AJ, Que L, Lipscomb JD.	Nat Prod Rep	10.1039/c7np00061h	2018
Metabolism	Denitrification by actinomycetes and purification of dissimilatory nitrite reductase and azurin from Streptomyces thioluteus.	Shoun H, Kano M, Baba I, Takaya N, Matsuo M.	J Bacteriol	10.1128/jb.180.17.4413-4415.1998	1998
Enzymology	In vitro reconstitution and crystal structure of p-aminobenzoate N-oxygenase (AurF) involved in aureothin biosynthesis.	Choi YS, Zhang H, Brunzelle JS, Nair SK, Zhao H.	Proc Natl Acad Sci U S A	10.1073/pnas.0712073105	2008
	Adaptation of Mycobacterium tuberculosis to Biofilm Growth Is Genetically Linked to Drug Tolerance.	Richards JP, Cai W, Zill NA, Zhang W, Ojha AK.	Antimicrob Agents Chemother	10.1128/aac.01213-19	2019
Metabolism	Characterisation of the Broadly-Specific O-Methyl-transferase JerF from the Late Stages of Jerangolid Biosynthesis.	Friedrich S, Hemmerling F, Lindner F, Warnke A, Wunderlich J, Berkhan G, Hahn F.	Molecules	10.3390/molecules21111443	2016
Metabolism	Crystal structure of CmlI, the arylamine oxygenase from the chloramphenicol biosynthetic pathway.	Knoot CJ, Kovaleva EG, Lipscomb JD.	J Biol Inorg Chem	10.1007/s00775-016-1363-x	2016
Metabolism	Nitroaromatic compounds, from synthesis to biodegradation.	Ju KS, Parales RE.	Microbiol Mol Biol Rev	10.1128/mmbr.00006-10	2010
Metabolism	Transcriptional Responses of the Bacterium Burkholderia terrae BS001 to the Fungal Host Lyophyllum sp. Strain Karsten under Soil-Mimicking Conditions.	Haq IU, Dini-Andreote F, van Elsas JD.	Microb Ecol	10.1007/s00248-016-0885-7	2017
	Characterisation of the mgo operon in Pseudomonas syringae pv. syringae UMAF0158 that is required for mangotoxin production.	Arrebola E, Carrion VJ, Cazorla FM, Perez-Garcia A, Murillo J, de Vicente A.	BMC Microbiol	10.1186/1471-2180-12-10	2012
Metabolism	Fungal Isocyanide Synthases and Xanthocillin Biosynthesis in Aspergillus fumigatus.	Lim FY, Won TH, Raffa N, Baccile JA, Wisecaver J, Rokas A, Schroeder FC, Keller NP.	mBio	10.1128/mbio.00785-18	2018
Enzymology	Marine Actinobacteria as a source of compounds for phytopathogen control: An integrative metabolic-profiling / bioactivity and taxonomical approach.	Betancur LA, Naranjo-Gaybor SJ, Vinchira-Villarraga DM, Moreno-Sarmiento NC, Maldonado LA, Suarez-Moreno ZR, Acosta-Gonzalez A, Padilla-Gonzalez GF, Puyana M, Castellanos L, Ramos FA.	PLoS One	10.1371/journal.pone.0170148	2017
Metabolism	Substrate recognition by the multifunctional cytochrome P450 MycG in mycinamicin hydroxylation and epoxidation reactions.	Li S, Tietz DR, Rutaganira FU, Kells PM, Anzai Y, Kato F, Pochapsky TC, Sherman DH, Podust LM.	J Biol Chem	10.1074/jbc.m112.410340	2012
Metabolism	The insect pathogen Serratia marcescens Db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycin.	Gerc AJ, Song L, Challis GL, Stanley-Wall NR, Coulthurst SJ.	PLoS One	10.1371/journal.pone.0044673	2012
Metabolism	Effects of Halide Ions on the Carbamidocyclophane Biosynthesis in Nostoc sp. CAVN2.	Preisitsch M, Heiden SE, Beerbaum M, Niedermeyer TH, Schneefeld M, Herrmann J, Kumpfmuller J, Thurmer A, Neidhardt I, Wiesner C, Daniel R, Muller R, Bange FC, Schmieder P, Schweder T, Mundt S.	Mar Drugs	10.3390/md14010021	2016
Enzymology	Identification of an unusual type II thioesterase in the dithiolopyrrolone antibiotics biosynthetic pathway.	Zhai Y, Bai S, Liu J, Yang L, Han L, Huang X, He J	Biochem Biophys Res Commun	10.1016/j.bbrc.2016.03.105	2016
Phylogeny	Taxonomic re-evaluation of whorl-forming Streptomyces (formerly Streptoverticillium) species by using phenotypes, DNA-DNA hybridization and sequences of gyrB, and proposal of Streptomyces luteireticuli (ex Katoh and Arai 1957) corrig., sp. nov., nom. rev.	Hatano K, Nishii T, Kasai H.	Int J Syst Evol Microbiol	10.1099/ijs.0.02238-0	2003
Phylogeny	Streptomyces zagrosensis sp. nov., isolated from soil.	Mohammadipanah F, Hamedi J, Sproer C, Rohde M, Montero-Calasanz MDC, Klenk HP	Int J Syst Evol Microbiol	10.1099/ijs.0.064527-0	2014

References

#9226	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 40027
#18466	Wink, J.: Compendium of Actinobacteria. HZI-Helmholtz-Centre for Infection Research, Braunschweig .
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#37414	; Curators of the CIP;
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68368	Automatically annotated from API 20E .
#68382	Automatically annotated from API zym .
#123523	Collection of Institut Pasteur ; Curators of the CIP; CIP 108140
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Streptomyces thioluteus (DSM 40027, ATCC 12310, CBS 642.72)

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