Schaalia odontolytica (DSM 43331, ATCC 17982, NCTC 9931)

Name: Schaalia odontolytica (DSM 43331, ATCC 17982, NCTC 9931)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 156

Type strain

Strain Designation 1A.21, A.21

Culture col. no. DSM 43331 ATCC 17982 NCTC 9931 WVU 868 1A.21 3 more

NCBI tax ID(s) 1660

Special Collections DSMZ CCUG CIP

Links

Schaalia odontolytica 1A.21 is an anaerobe, mesophilic human pathogen that was isolated from carious lesions of the human dentine.

anaerobe mesophilic human pathogen genome sequence 16S sequence

Name and taxonomic classification

SI-ID 36796

ATCC 17982,NCTC 9931,CCUG 4866,CCUG 18309,IMET 10975,DSM 43331,CIP 104728,CECT 807,NCYC 9931

@ref 20215

Last LPSN update 2025-12-16 09:46:47

Domain Bacillati

Phylum Actinomycetota

Class Actinomycetes

Order Actinomycetales

Family Actinomycetaceae

Genus Schaalia

Species Schaalia odontolytica

Full scientific name Schaalia odontolytica (Batty 1958) Nouioui et al. 2018

Synonyms (1)

Actinomyces odontolyticus

BacDive ID	Other strains from **Schaalia odontolytica** (88)	Type strain
155	S. odontolytica 2A.10, X363, DSM 19120, ATCC 17929, CCUG ... (type strain)
135507	S. odontolytica 92 LP/83, CIP 100291
136019	S. odontolytica CIP 101336
136021	S. odontolytica CIP 101862
137279	S. odontolytica W1514, CIP 104843, CCUG 34705, ATCC 29323
137587	S. odontolytica 55-87, CIP 102828
137635	S. odontolytica 591-86, CIP 102601
137766	S. odontolytica CIP 101482
137921	S. odontolytica CIP 102192
138046	S. odontolytica CIP 102579
144081	S. odontolytica CCUG 22864
144200	S. odontolytica CCUG 23548
144919	S. odontolytica CCUG 27093
144920	S. odontolytica CCUG 27094
144921	S. odontolytica CCUG 27095
145285	S. odontolytica CCUG 28084
145962	S. odontolytica CCUG 29966
146514	S. odontolytica CCUG 31358
146589	S. odontolytica CCUG 31532
146604	S. odontolytica CCUG 31570
146795	S. odontolytica CCUG 32130
146847	S. odontolytica CCUG 32239
146901	S. odontolytica CCUG 32402
146921	S. odontolytica CCUG 32454
146974	S. odontolytica CCUG 32583
147088	S. odontolytica CCUG 32833
147089	S. odontolytica CCUG 32834
147090	S. odontolytica CCUG 32835
147091	S. odontolytica CCUG 32836
147092	S. odontolytica CCUG 32837
147116	S. odontolytica CCUG 32892
147117	S. odontolytica CCUG 32893
147119	S. odontolytica CCUG 32895
147120	S. odontolytica CCUG 32896
147121	S. odontolytica CCUG 32897
147156	S. odontolytica CCUG 32966 A
147347	S. odontolytica CCUG 33415
147396	S. odontolytica CCUG 33520
147468	S. odontolytica CCUG 33620
147483	S. odontolytica CCUG 33681
147499	S. odontolytica CCUG 33705
147500	S. odontolytica CCUG 33706
147540	S. odontolytica CCUG 33767
147640	S. odontolytica CCUG 33931
147726	S. odontolytica CCUG 34102
147727	S. odontolytica CCUG 34103
147728	S. odontolytica CCUG 34104
147729	S. odontolytica CCUG 34105
147730	S. odontolytica CCUG 34106
147731	S. odontolytica CCUG 34107
147732	S. odontolytica CCUG 34108
147959	S. odontolytica CCUG 34580
148020	S. odontolytica CCUG 34688
148021	S. odontolytica CCUG 34689
148076	S. odontolytica CCUG 34777
148093	S. odontolytica CCUG 34807
148171	S. odontolytica CCUG 34967
148197	S. odontolytica CCUG 35022
148199	S. odontolytica CCUG 35024
149055	S. odontolytica CCUG 36794
149219	S. odontolytica CCUG 37290
149276	S. odontolytica CCUG 37391
149282	S. odontolytica CCUG 37402
149531	S. odontolytica CCUG 37916
149691	S. odontolytica CCUG 38200
150140	S. odontolytica CCUG 39079
150553	S. odontolytica CCUG 41574
150570	S. odontolytica CCUG 41634
150699	S. odontolytica CCUG 41982
151046	S. odontolytica CCUG 43155
151343	S. odontolytica CCUG 43800
151357	S. odontolytica CCUG 43840
151715	S. odontolytica CCUG 44701
152095	S. odontolytica CCUG 45733
152228	S. odontolytica CCUG 46173
152646	S. odontolytica CCUG 47277
152944	S. odontolytica CCUG 48087
153238	S. odontolytica CCUG 48844
153396	S. odontolytica CCUG 49468
154351	S. odontolytica CCUG 53208
155141	S. odontolytica CCUG 56576
155142	S. odontolytica CCUG 56577
155589	S. odontolytica CCUG 58282
155825	S. odontolytica CCUG 59407
156199	S. odontolytica CCUG 60702
156201	S. odontolytica CCUG 60705
156204	S. odontolytica CCUG 60720
156419	S. odontolytica CCUG 61657

Morphology

Cell morphology

@ref	Motility	Confidence
125438		96.875
125439		98.4
125439		92.9

Culture and growth conditions

Culture medium

@ref	Name	Composition
39862	MEDIUM 6 - Columbia agar with 10 % horse blood	Distilled water make up to (1000.000 ml);Columbia agar (39.000 g);Horseblood (100.000 ml)
10959	COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)	Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
10959	PYG MEDIUM (MODIFIED) (DSMZ Medium 104)	Name: PYG MEDIUM (MODIFIED) (DSMZ Medium 104) Composition: Yeast extract 10.0 g/l Peptone 5.0 g/l Trypticase peptone 5.0 g/l Beef extract 5.0 g/l Glucose 5.0 g/l L-Cysteine HCl x H2O 0.5 g/l NaHCO3 0.4 g/l NaCl 0.08 g/l K2HPO4 0.04 g/l KH2PO4 0.04 g/l MgSO4 x 7 H2O 0.02 g/l CaCl2 x 2 H2O 0.01 g/l Hemin 0.005 g/l Ethanol 0.0038 g/l Resazurin 0.001 g/l Tween 80 Vitamin K1 NaOH Distilled water
121390	CIP Medium 6

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
10959	positive	growth	37	mesophilic
39862	positive	growth	37	mesophilic

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance
10959	anaerobe
10959	microaerophile
125439	anaerobe

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68380	29016 ChEBI	arginine	-	hydrolysis	from API rID32A
68380	29985 ChEBI	L-glutamate	-	degradation	from API rID32A
68380	17632 ChEBI	nitrate	+	reduction	from API rID32A
68380	27897 ChEBI	tryptophan	-	energy source	from API rID32A
68380	16199 ChEBI	urea	-	hydrolysis	from API rID32A

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68380	35581 ChEBI	indole		from API rID32A

Metabolite tests

@ref	Chebi-ID	Metabolite	Indole test
68380	35581 ChEBI	indole	-	from API rID32A

Enzymes

@ref	Value	Activity	Ec
68380	alanine arylamidase	+	3.4.11.2	from API rID32A
68380	alkaline phosphatase	-	3.1.3.1	from API rID32A
68380	alpha-arabinosidase	-	3.2.1.55	from API rID32A
68380	alpha-glucosidase	+	3.2.1.20	from API rID32A
68380	arginine dihydrolase	-	3.5.3.6	from API rID32A
68380	beta-galactosidase	+	3.2.1.23	from API rID32A
68380	beta-Galactosidase 6-phosphate	-		from API rID32A
68380	beta-glucosidase	+	3.2.1.21	from API rID32A
68380	beta-glucuronidase	-	3.2.1.31	from API rID32A
68380	glutamate decarboxylase	-	4.1.1.15	from API rID32A
68380	glutamyl-glutamate arylamidase	-		from API rID32A
68380	glycin arylamidase	+		from API rID32A
68380	L-arginine arylamidase	+		from API rID32A
68380	leucine arylamidase	+	3.4.11.1	from API rID32A
68380	leucyl glycin arylamidase	+	3.4.11.1	from API rID32A
68380	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API rID32A
68380	phenylalanine arylamidase	+		from API rID32A
68380	proline-arylamidase	+	3.4.11.5	from API rID32A
68380	pyrrolidonyl arylamidase	-	3.4.19.3	from API rID32A
68380	serine arylamidase	+		from API rID32A
68380	tryptophan deaminase	-	4.1.99.1	from API rID32A
68380	tyrosine arylamidase	+		from API rID32A
68380	urease	-	3.5.1.5	from API rID32A

API rID32A

@ref	URE	ADH (Arg)	alpha GAL	beta GAL	beta-Galactosidase 6-phosphatebeta GP	alpha GLU	beta GLU	alpha ARA	beta GUR	beta-N-Acetyl-beta-glucosaminidasebeta NAG	MNE	RAF	GDC	alpha FUC	Reduction of nitrateNIT	IND	PAL	L-arginine arylamidaseArgA	ProA	LGA	Phenylalanine arylamidasePheA	Leucine arylamidaseLeuA	PyrA	Tyrosine arylamidaseTyrA	Alanine arylamidaseAlaA	Glycin arylamidaseGlyA	Histidine arylamidaseHisA	Glutamyl-glutamate arylamidaseGGA	Serine arylamidaseSerA
10959	-	-	-	+	-	+	+	-	-	-	+	+	-	-	+	-	-	+	+	+	+	+	-	+	+	+	+/-	-	+
10959	-	-	+	+	-	+	+	-	-	-	-	+/-	-	+/-	+	-	-	+	+	+	+	+	-	+	+	+	+	-	+

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2
#Host	#Human
#Host Body-Site	#Oral cavity and airways
#Host Body-Site	#Other

Isolation

@ref	Sample type
10959	carious lesions of the human dentine
121390	Human, Carious lesions of the dentine

Interaction and safety

Risk assessment

@ref	Pathogenicity human	Pathogenicity animal	Biosafety level	Biosafety level comment
10959			2	Risk group (German classification) According to TRBA 466
121390			2	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM15422v1 assembly for Schaalia dentiphila ATCC 17982	scaffold	GCA_000154225	411466.7	640963058	411466	79.11

Genome browser: GCA_000154225

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
124043	Actinomyces odontolyticus 16S rRNA gene, strain CCUG 18309	AJ234037	1392	1660
124043	Schaalia odontolytica strain NCTC 9931 16S ribosomal RNA gene, partial sequence.	OR133757	1548	1660
124043	Actinomyces odontolyticus partial 16S rRNA	X53227	1375	411466

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Schaalia odontolytica ATCC 17982
NCBI: GCA_000154225

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	79.20	no
125439	motility	BacteriaNetⓘ	no	92.90	no
125439	gram_stain	BacteriaNetⓘ	positive	98.40	no
125439	oxygen_tolerance	BacteriaNetⓘ	anaerobe	90.90	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Schaalia odontolytica ATCC 17982 ATCC 17982
NCBI: GCA_000154225.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	89.92	no
125438	anaerobic	anaerobicⓘ	no	71.75	no
125438	aerobic	aerobicⓘ	no	78.28	yes
125438	spore-forming	spore-formingⓘ	no	83.59	no
125438	thermophilic	thermophileⓘ	no	92.79	no
125438	flagellated	motile2+ⓘ	no	96.88	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Metabolism	Characterization of RbmD (glycosyltransferase in ribostamycin gene cluster) through neomycin production reconstituted from the engineered Streptomyces fradiae BS1.	Nepal KK, Oh TJ, Subba B, Yoo JC, Sohng JK.	Mol Cells	10.1007/s10059-009-0008-0	2009
Metabolism	Production of aminoglycosides in non-aminoglycoside producing Streptomyces lividans TK24.	Subba B, Kurumbang NP, Jung YS, Yoon YJ, Lee HC, Liou K, Sohng JK.	Bioorg Med Chem Lett	10.1016/j.bmcl.2007.01.035	2007
	Induction of inflammatory cytokines by a soluble moiety prepared from an enzyme lysate of Actinomyces viscosus cell walls.	Takada H, Kimura S, Hamada S.	J Med Microbiol	10.1099/00222615-38-6-395	1993
Metabolism	Metagenomic analysis of nitrate-reducing bacteria in the oral cavity: implications for nitric oxide homeostasis.	Hyde ER, Andrade F, Vaksman Z, Parthasarathy K, Jiang H, Parthasarathy DK, Torregrossa AC, Tribble G, Kaplan HB, Petrosino JF, Bryan NS.	PLoS One	10.1371/journal.pone.0088645	2014
Enzymology	Pantothenate kinase from the thermoacidophilic archaeon Picrophilus torridus.	Takagi M, Tamaki H, Miyamoto Y, Leonardi R, Hanada S, Jackowski S, Chohnan S.	J Bacteriol	10.1128/jb.01021-09	2010
	Identifying essential genes in Schaalia odontolytica using a saturated transposon library.	Bedree JK, Bourgeois J, Balani P, Cen L, Hendrickson EL, Kerns KA, Camilli A, McLean JS, Shi W, He X.	J Bacteriol	10.1128/jb.00164-25	2025
	Exploitation of a Bacterium-Encoded Lytic Transglycosylase by a Human Oral Lytic Phage To Facilitate Infection.	Cen L, Chang Y, Bedree JK, Ma Y, Zhong Q, Utter DR, Dong PT, Lux R, Bor B, Liu J, McLean JS, Le S, He X.	J Virol	10.1128/jvi.01063-22	2022
Phylogeny	Age and sex-related variations in murine laryngeal microbiota.	An R, Venkatraman A, Binns J, Saric C, Rey FE, Thibeault SL.	PLoS One	10.1371/journal.pone.0300672	2024
Phylogeny	Offline Next Generation Metagenomics Sequence Analysis Using MinION Detection Software (MINDS).	Deshpande SV, Reed TM, Sullivan RF, Kerkhof LJ, Beigel KM, Wade MM.	Genes (Basel)	10.3390/genes10080578	2019
	Single-cell view into the role of microbiota shaping host immunity in the larynx.	An R, Ni Z, Xie E, Rey FE, Kendziorski C, Thibeault SL.	iScience	10.1016/j.isci.2024.110156	2024
	ATP synthase evolution on a cross-braced dated tree of life.	Mahendrarajah TA, Moody ERR, Schrempf D, Szantho LL, Dombrowski N, Davin AA, Pisani D, Donoghue PCJ, Szollosi GJ, Williams TA, Spang A.	Nat Commun	10.1038/s41467-023-42924-w	2023
	In Vitro Cultivation of 'Unculturable' Oral Bacteria, Facilitated by Community Culture and Media Supplementation with Siderophores.	Vartoukian SR, Adamowska A, Lawlor M, Moazzez R, Dewhirst FE, Wade WG.	PLoS One	10.1371/journal.pone.0146926	2016
Pathogenicity	The effects of chlorhexidine gluconate (0.12%) on the antimicrobial properties of tooth-colored ProRoot mineral trioxide aggregate.	Stowe TJ, Sedgley CM, Stowe B, Fenno JC	J Endod	10.1097/00004770-200406000-00013	2004
Metabolism	Human salivary acidic proline-rich proteins and statherin promote the attachment of Actinomyces viscosus LY7 to apatitic surfaces.	Gibbons RJ, Hay DI	Infect Immun	10.1128/iai.56.2.439-445.1988	1988
Genetics	Genome characterisation and comparative analysis of Schaalia dentiphila sp. nov. and its subspecies, S. dentiphila subsp. denticola subsp. nov., from the human oral cavity.	Tian X, Teo WFA, Yang Y, Dong L, Wong A, Chen L, Ahmed H, Choo SW, Jakubovics NS, Tan GYA.	BMC Microbiol	10.1186/s12866-024-03346-w	2024
Genetics	Genome characterization and taxonomy of Actinomyces acetigenes sp. nov., and Actinomyces stomatis sp. nov., previously isolated from the human oral cavity.	Tian X, Teo WFA, Wee WY, Yang Y, Ahmed H, Jakubovics NS, Choo SW, Tan GYA.	BMC Genomics	10.1186/s12864-023-09831-2	2023

References

#10959	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 43331
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#39862	; Curators of the CIP;
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#68380	Automatically annotated from API rID32A .
#121390	Collection of Institut Pasteur ; Curators of the CIP; CIP 104728
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Schaalia odontolytica (DSM 43331, ATCC 17982, NCTC 9931)

Name and taxonomic classification

Morphology

Cell morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Metabolite utilization

Metabolite production

Metabolite tests

Enzymes

API rID32A

Isolation, sampling and environmental information

Isolation source categories

Isolation

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_000154225

16S sequences

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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