Streptomyces griseosporeus (DSM 40562, ATCC 27435, CBS 137.72)

Name: Streptomyces griseosporeus (DSM 40562, ATCC 27435, CBS 137.72)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 15280

Type strain

Strain Designation B-793

Culture col. no. DSM 40562 ATCC 27435 CBS 137.72 CBS 759.72 IFO 13458 11 more

NCBI tax ID(s) 1910

Special Collections DSMZ JCM Wink compendium JMRC

History DSMZ <- E.B. Shirling, ISP <- T. Niida, Meiji Seika Kaisha, B-793 JCM <-- KCC S-0766 <-- IFO 13458 <-- SAJ <-- ISP 5562 <-- Meiji Seika Kaisha, Ltd.; B-793 (MS 1104).

Links

Streptomyces griseosporeus B-793 is a bacterium that builds an aerial mycelium and produces antibiotic compounds.

antibiotic compound production genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 39002

ATCC 27435,IFO 13458,DSM 40562,JCM 4766,IMET 43543,NRRL B-12498,VKM Ac-1731,CBS 759.72,NBRC 13458,HAMBI 1009,BCRC 15195,CCRC 15195

@ref 20215

Last LPSN update 2026-05-29 08:28:30

Domain Bacteria

Phylum Actinomycetota

Class Actinomycetes

Order Kitasatosporales

Family Streptomycetaceae

Genus Streptomyces

Species Streptomyces griseosporeus

Full scientific name Streptomyces griseosporeus Niida and Ogasawara 1960 (Approved Lists 1980)

BacDive ID	Other strains from **Streptomyces griseosporeus** (2)	Type strain
128248	S. griseosporeus SF002236,
128249	S. griseosporeus SF003756,

Morphology

Cell morphology

@ref	Motility	Confidence	Gram stain
125439		93.141
125439		98.846	positive

Colony morphology

@ref	Colony color	Incubation period	Medium used
18657	Beige (1001)	10-14 days	ISP 2
18657	Brown	10-14 days	ISP 3
18657		10-14 days	ISP 4
18657	Yellow	10-14 days	ISP 5
18657		10-14 days	ISP 6
18657	Beige (1001)	10-14 days	ISP 7

Multicellular morphology

@ref	Complex name	Complex color	Medium name
18657	Aerial Mycelium	White	ISP 2
18657	Aerial Mycelium	Grey	ISP 3
18657	Aerial Mycelium	White/Grey	ISP 4
18657	Aerial Mycelium	White	ISP 5
18657			ISP 6
18657	Aerial Mycelium	White	ISP 7

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
9644	GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)	Medium recipe at MediaDive	Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water
18657	ISP 2		Name: ISP 2 / Yeast Malt Agar (5265); 5265 Composition Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l Agar 15.0 g/l Preparation: Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.0 Usage: Maintenance and Taxonomy Organisms: All Actinomycetes
18657	ISP 3		Name: ISP 3; 5315 Composition Dog oat flakes 20.0 g/l Trace element solution (5314) 2.5 ml/l Agar 18.0 g/l Preparation: Oat flakes are cooked for 20 minutes, trace element solution and agar are added (in the case of non rolled oat flakes the suspension has to bee filtrated). Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.8 Usage: Maintenance and taxonomy (e.g. SEM As liquid medium for metabolite production) Organisms: All Actinomycetes Trace element solution 5314 Name: Trace element solution 5314; 5314 Composition CaCl2 x H2O 3.0 g/l Fe-III-citrate 1.0 g/l MnSO4 0.2 g/l ZnCl2 0.1 g/l CuSO4 x 5 H2O 0.025 g/l Sodium tetra borate 0.2 g/l CoCl2 x 6 H2O 0.004 g/l Sodium molybdate 0.01 g/l Preparation: Use double destillated water. Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Trace element solution for different media Organisms:
18657	ISP 4		Name: ISP 4; DSM 547 Solution I: Difco soluble starch, 10.0 g. Make a paste of the starch with a small amount of cold distilled water and bring to a volume of 500 ml. Solution II: CaCO3 2.0 g K2HPO4 (anhydrous) 1.0 g MgSO4 x 7 H2O 1.0 g NaCl 1.0 g (NH4)2SO4 2.0 g Distilled water 500.0 ml Trace salt solution (see below) 1.0 ml The pH should be between 7.0 and 7.4. Do not adjust if it is within this range. Mix solutions I and II together. Add 20.0 g agar. Liquify agar by steaming at 100°C for 10 to 20 min. Trace element solution: FeSO4 x 7 H2O 0.1 g MnCl2 x 4 H2O 0.1 g ZnSO4 x 7 H2O 0.1 g Distilled water 100.0 ml
18657	ISP 5		Name: ISP 5 (5323) Composition L-Asparagine 1.0 g/l Glycerol 10.0 g/l K2HPO4 1.0 g/l Salt solution (see preparation) 1.0 ml/l Agar 20.0 g/l Preparation: Salt solution 1.0 g FeSO4 x 7 H2O 1.0 g MnCl2 x 4 H2O 1.0 g ZNSO4 x 7 H2O in 100 ml water Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.2 Usage: Maintenance and taxonomy Organisms: All Actinomycetes
18657	ISP 6		Name: ISP 6 (5318) Composition Peptone 15.0 g/l Proteose peptose 5.0 g/l Ferric ammonium citrate 0.5 g/l Sodium glycerophosphate 1.0 g/l Sodium thiosulfate 0.08 g/l Yeast extract 1.0 g/l Agar 15.0 g/l Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Production of melanoid pigments Organisms: All Actinomycetes
18657	ISP 7		Name: ISP 7 (5322) Composition Glycerol 15.0 g/l L-Tyrosine 0.5 g/l L-Asparagine 1.0 g/l K2HPO4 0.5 g/l NaCl 0.5 g/l FeSO4 x 7 H2O 0.01 g/l Trace element solution 5343 1.0 ml/l Agar 20.0 Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.3 Usage: Production of melanoid pigments Organisms: All Actinomycetes
9644	ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84)	Medium recipe at MediaDive	Name: ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84) Composition: Agar 20.0 g/l Rolled oats 20.0 g/l ZnSO4 x 7 H2O 0.001 g/l MnCl2 x 4 H2O 0.001 g/l FeSO4 x 7 H2O 0.001 g/l Distilled water

Culture temp

@ref	Growth	Type	Temperature (°C)
9644	positive	growth	28
18657	positive	optimum	28
67770	positive	growth	28

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
125439	obligate aerobe	99.072

Spore formation

@ref	Spore formation	Confidence
125438		92.458
125439		91.948

Compound production

@ref	Compound
9644	taitomycin
20216	Taitomycin
67770	Taitomycin

Halophily

@ref	Salt	Growth	Tested relation	Concentration
18657	NaCl	positive	maximum	5 %

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
18657	22599 ChEBI	arabinose	+/-
68368	29016 ChEBI	arginine	-	hydrolysis	from API 20E
68368	16947 ChEBI	citrate	-	assimilation	from API 20E
18657	28757 ChEBI	fructose	+/-
68368	5291 ChEBI	gelatin	+	hydrolysis	from API 20E
18657	17234 ChEBI	glucose	+
68368	25094 ChEBI	lysine	-	degradation	from API 20E
18657	29864 ChEBI	mannitol	+/-
18657	17268 ChEBI	myo-inositol	+/-
68368	18257 ChEBI	ornithine	-	degradation	from API 20E
18657	16634 ChEBI	raffinose	+/-
18657	26546 ChEBI	rhamnose	+/-
18657	17992 ChEBI	sucrose	+
68368	27897 ChEBI	tryptophan	-	energy source	from API 20E
68368	16199 ChEBI	urea	-	hydrolysis	from API 20E
18657	18222 ChEBI	xylose	-

Metabolite production

@ref	Chebi-ID	Metabolite
68368	15688 ChEBI	acetoin	from API 20E
68368	16136 ChEBI	hydrogen sulfide	from API 20E
68368	35581 ChEBI	indole	from API 20E

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Indole test
68368	15688 ChEBI	acetoin	+		from API 20E
68368	35581 ChEBI	indole		-	from API 20E

Enzymes

@ref	Value	Activity	Ec
68368	arginine dihydrolase	-	3.5.3.6	from API 20E
68368	beta-galactosidase	+	3.2.1.23	from API 20E
68368	gelatinase	+		from API 20E
68368	lysine decarboxylase	-	4.1.1.18	from API 20E
68368	ornithine decarboxylase	-	4.1.1.17	from API 20E
68368	tryptophan deaminase	+	4.1.99.1	from API 20E
68368	urease	-	3.5.1.5	from API 20E

API 20E

@ref	ONPG	ADH (Arg)	LDC (Lys)	ODC	CIT	H2S productionH2S	URE	TDA (Trp)	IND	Acetoin production (Voges Proskauer test)VP	GEL	GLU	MAN	INO	Sor	RHA	SAC	MEL	AMY	ARA	OX	Nitrite productionNO2	Reduction to N2N2	MotilityMOB	Growth on MacConkey mediumMAC	OF-O	OF-F
18657	+	-	-	-	-	-	-	+	-	+	+	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.

Isolation, sampling and environmental information

Isolation

@ref	Sample type	Geographic location	Country	Country ISO 3 Code	Continent
67770	Soil	Taito district, Formosa	Japan	JPN	Asia

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
18657	1	German classification According to TRBA 466
9644	1	Risk group (German classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM1465605v1 assembly for Streptomyces griseosporeus JCM 4766	scaffold	GCA_014656055	1910.4	8109914692	1910	74.57

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Streptomyces griseosporeus gene for 16S rRNA, partial sequence	AB122717	564	1910
20218	Streptomyces griseosporeus gene for 16S ribosomal RNA, partial sequence, strain: JCM 4766	D44345	120	1910
20218	Streptomyces griseosporeus gene for 16S rRNA, partial sequence, strain: NBRC 13458	AB184419	1468	1910
124043	Streptomyces griseosporeus strain JCM 4766 16S ribosomal RNA gene, partial sequence.	MT760609	1394	1910

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: ASM1465605v1 assembly for Streptomyces griseosporeus JCM 4766
NCBI: GCA_014656055

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	99.07	no
125439	gram_stain	BacteriaNetⓘ	positive	98.85	no
125439	spore_formation	BacteriaNetⓘ	yes	91.95	no
125439	motility	BacteriaNetⓘ	no	93.14	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Streptomyces griseosporeus JCM 4766
NCBI: GCA_014656055.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	89.96	no
125438	anaerobic	anaerobicⓘ	no	96.50	no
125438	aerobic	aerobicⓘ	yes	87.87	no
125438	spore-forming	spore-formingⓘ	yes	92.46	no
125438	thermophilic	thermophileⓘ	no	95.50	no
125438	flagellated	motile2+ⓘ	no	87.50	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Metabolism	Liposidomycin, the first reported nucleoside antibiotic inhibitor of peptidoglycan biosynthesis translocase I: The discovery of liposidomycin and related compounds with a perspective on their application to new antibiotics.	Kimura KI.	J Antibiot (Tokyo)	10.1038/s41429-019-0241-5	2019
	New liposidomycin congeners produced by Streptomyces sp. TMPU-20A065, anti-Mycobacterium avium complex agents with therapeutic efficacy in a silkworm infection model.	Yagi A, Fujiwara M, Sato M, Abe Y, Uchida R.	J Antibiot (Tokyo)	10.1038/s41429-024-00724-4	2024
	Reaction of COTC with glutathione: structure of the putative glyoxalase I inhibitor.	Huntley CF, Hamilton DS, Creighton DJ, Ganem B.	Org Lett	10.1021/ol006341z	2000
	Crystallization and preliminary crystallographic data of the alpha-amylase inhibitors, Haim I and Paim I.	Miyagawa M, Fukuhara K, Katayanagi K, Ishimaru K, Morikawa K, Matsuzaki T, Sato Y, Hara S, Ikenaka T, Arai M.	J Biochem	10.1093/oxfordjournals.jbchem.a124295	1994
Metabolism	FK409, a novel vasodilator isolated from the acid-treated fermentation broth of Streptomyces griseosporeus. III. Reaction mechanism and synthesis.	Hino M, Takase S, Itoh Y, Uchida I, Okamoto M, Kohsaka M, Aoki H, Imanaka H.	J Antibiot (Tokyo)	10.7164/antibiotics.42.1589	1989
Metabolism	FK409, a novel vasodilator isolated from the acid-treated fermentation broth of Streptomyces griseosporeus. I. Taxonomy, fermentation, isolation, and physico-chemical and biological characteristics.	Hino M, Iwami M, Okamoto M, Yoshida K, Haruta H, Okuhara M, Hosoda J, Kohsaka M, Aoki H, Imanaka H.	J Antibiot (Tokyo)	10.7164/antibiotics.42.1578	1989
	FK409, a novel vasodilator isolated from the acid-treated fermentation broth of Streptomyces griseosporeus. II. Structure of FK409 and its precursor FR-900411.	Hino M, Ando T, Takase S, Itoh Y, Okamoto M, Kohsaka M, Aoki H, Imanaka H.	J Antibiot (Tokyo)	10.7164/antibiotics.42.1584	1989
Enzymology	Molecular cloning and expression in Streptomyces lividans of a proteinous alpha-amylase inhibitor (HaimII) gene from Streptomyces griseosporeus.	Saito S, Takahashi H, Saito H, Arai M, Murao S.	Biochem Biophys Res Commun	10.1016/s0006-291x(86)80156-5	1986
Enzymology	Amino acid sequence of protein alpha-amylase inhibitor from Streptomyces griseosporeus YM-25.	Murai H, Hara S, Ikenaka T, Goto A, Arai M, Murao S.	J Biochem	10.1093/oxfordjournals.jbchem.a135157	1985
Metabolism	gamma-Chloronorvaline, a leucine analog from Streptomyces.	Narayanan S, Iyengar MR, Ganju PL, Rengaraju S, Shomura T, Tsuruoka T, Inouye S, Niida T.	J Antibiot (Tokyo)	10.7164/antibiotics.33.1249	1980
	The structure of a glyoxalase I inhibitor and its chemical reactivity with SH-compounds.	Chimura H, Nakamura H, Takita T, Takeuchi T, Umezawa H.	J Antibiot (Tokyo)	10.7164/antibiotics.28.743	1975
	Nucleotide sequence and expression of a Streptomyces griseosporeus proteinaceous alpha-amylase inhibitor (HaimII) gene.	Nagaso H, Saito S, Saito H, Takahashi H.	J Bacteriol	10.1128/jb.170.10.4451-4457.1988	1988
	Protective role of nitric oxide in ischemia and reperfusion injury of the liver.	Shimamura T, Zhu Y, Zhang S, Jin MB, Ishizaki N, Urakami A, Totsuka E, Kishida A, Lee R, Subbotin V, Furukawa H, Starzl TE, Todo S.	J Am Coll Surg	10.1016/s1072-7515(98)00259-2	1999

References

#9644	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 40562
#18657	Wink, J.: Compendium of Actinobacteria. HZI-Helmholtz-Centre for Infection Research, Braunschweig .
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20216	Curators of the JMRC: Jena Microbial Resource Collection (JMRC):
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68368	Automatically annotated from API 20E .
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

Rate our new design

Content

About us

Streptomyces griseosporeus (DSM 40562, ATCC 27435, CBS 137.72)

Name and taxonomic classification

Morphology

Cell morphology

Colony morphology

Multicellular morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Compound production

Halophily

Metabolite utilization

Metabolite production

Metabolite tests

Enzymes

API 20E

Isolation, sampling and environmental information

Isolation

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_014656055

16S sequences

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

Help

Social Media