Alistipes inops 627 is a mesophilic prokaryote that was isolated from human faeces, healthy men.
mesophilic genome sequence| @ref 20215 |
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| Domain Pseudomonadati |
| Phylum Bacteroidota |
| Class Bacteroidia |
| Order Bacteroidales |
| Family Rikenellaceae |
| Genus Alistipes |
| Species Alistipes inops |
| Full scientific name Alistipes inops Shkoporov et al. 2015 |
| @ref | Gram stain | Confidence | |
|---|---|---|---|
| 125439 | negative | 98.3 |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 42732 | CHOPPED MEAT MEDIUM (DSMZ Medium 78) | Medium recipe at MediaDive | Name: CHOPPED MEAT MEDIUM (DSMZ Medium 78) Composition: Ground beef 500.0 g/l Casitone 30.0 g/l Agar 15.0 g/l Ethanol 9.5 g/l (optional) K2HPO4 5.0 g/l Yeast extract 5.0 g/l L-Cysteine HCl 0.5 g/l Haemin 0.005 g/l (optional) Resazurin 0.001 g/l Vitamin K3 0.0005 g/l (optional) Vitamin K1 (optional) NaOH (optional) Distilled water |
| @ref | Oxygen tolerance | Confidence | |
|---|---|---|---|
| 125439 | anaerobe | 94.7 |
| @ref | Spore formation | Confidence | |
|---|---|---|---|
| 125439 | 99.1 |
| 67770 | Observationquinones: MK-10, MK-11 |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68380 | 29016 ChEBI | arginine | - | hydrolysis | from API rID32A |
| 68380 | 16024 ChEBI | D-mannose | - | fermentation | from API rID32A |
| 68380 | 29985 ChEBI | L-glutamate | + | degradation | from API rID32A |
| 68380 | 17632 ChEBI | nitrate | - | reduction | from API rID32A |
| 68380 | 16634 ChEBI | raffinose | - | fermentation | from API rID32A |
| 68380 | 27897 ChEBI | tryptophan | + | energy source | from API rID32A |
| 68380 | 16199 ChEBI | urea | - | hydrolysis | from API rID32A |
| @ref | Chebi-ID | Metabolite | Production | |
|---|---|---|---|---|
| 68380 | 35581 ChEBI | indole | from API rID32A |
| @ref | Chebi-ID | Metabolite | Indole test | |
|---|---|---|---|---|
| 68380 | 35581 ChEBI | indole | + | from API rID32A |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68380 | alanine arylamidase | + | 3.4.11.2 | from API rID32A |
| 68380 | alkaline phosphatase | - | 3.1.3.1 | from API rID32A |
| 68380 | alpha-arabinosidase | - | 3.2.1.55 | from API rID32A |
| 68380 | alpha-fucosidase | - | 3.2.1.51 | from API rID32A |
| 68380 | alpha-galactosidase | - | 3.2.1.22 | from API rID32A |
| 68380 | alpha-glucosidase | - | 3.2.1.20 | from API rID32A |
| 68380 | arginine dihydrolase | - | 3.5.3.6 | from API rID32A |
| 68380 | beta-galactosidase | - | 3.2.1.23 | from API rID32A |
| 68380 | beta-Galactosidase 6-phosphate | - | from API rID32A | |
| 68380 | beta-glucosidase | - | 3.2.1.21 | from API rID32A |
| 68380 | beta-glucuronidase | - | 3.2.1.31 | from API rID32A |
| 68380 | glutamate decarboxylase | + | 4.1.1.15 | from API rID32A |
| 68380 | glutamyl-glutamate arylamidase | + | from API rID32A | |
| 68380 | glycin arylamidase | - | from API rID32A | |
| 68380 | histidine arylamidase | - | from API rID32A | |
| 68380 | L-arginine arylamidase | - | from API rID32A | |
| 68380 | leucine arylamidase | - | 3.4.11.1 | from API rID32A |
| 68380 | leucyl glycin arylamidase | + | 3.4.11.1 | from API rID32A |
| 68380 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API rID32A |
| 68380 | phenylalanine arylamidase | - | from API rID32A | |
| 68380 | proline-arylamidase | - | 3.4.11.5 | from API rID32A |
| 68380 | pyrrolidonyl arylamidase | - | 3.4.19.3 | from API rID32A |
| 68380 | serine arylamidase | - | from API rID32A | |
| 68380 | tryptophan deaminase | + | 4.1.99.1 | from API rID32A |
| 68380 | tyrosine arylamidase | - | from API rID32A | |
| 68380 | urease | - | 3.5.1.5 | from API rID32A |
| @ref | Biosafety level | Biosafety level comment | |
|---|---|---|---|
| 42732 | 1 | Risk group (German classification) |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 67770 | ASM78657v1 assembly for Alistipes inops 627 | contig | 1501391 | 62.79 |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Melatonin Ameliorates Depressive-Like Behaviors in Ovariectomized Mice by Improving Tryptophan Metabolism via Inhibition of Gut Microbe Alistipes Inops. | Zheng KY, Gao B, Wang HJ, He JG, Chen HS, Hu ZL, Long LH, Chen JG, Wang F. | Adv Sci (Weinh) | 10.1002/advs.202309473 | 2024 | ||
| Initial gut microbiota composition is a determining factor in the promotion of colorectal cancer by oral iron supplementation: evidence from a murine model. | Cuisiniere T, Hajjar R, Oliero M, Calve A, Fragoso G, Rendos HV, Gerkins C, Taleb N, Gagnon-Konamna M, Dagbert F, Loungnarath R, Sebajang H, Schwenter F, Wassef R, Ratelle R, De Broux E, Richard C, Santos MM. | Microbiome | 10.1186/s40168-025-02101-1 | 2025 | ||
| Genetics | Gut Microbiota Is Not Significantly Altered by Radioiodine Therapy. | Barata P, Oliveira A, Soares R, Fernandes A. | Nutrients | 10.3390/nu17030395 | 2025 | |
| Genetics | Characterization of gut microbiota and metabolites in individuals with constipation-predominant irritable bowel syndrome. | Wang YL, Xu XQ, Long YY, Cheng YL. | Front Microbiol | 10.3389/fmicb.2025.1617288 | 2025 | |
| Inactivated Lactiplantibacillus plantarum Ps-8 enhances growth performance and intestinal health in broiler chickens via gut microbiota and serum metabolite modulation. | Jiao Y, Huang W, Zhang Q, Liu L, Zhao J, Chen Y. | Poult Sci | 10.1016/j.psj.2025.105611 | 2025 | ||
| Intermittent MDMA Attenuates Ovariectomy-induced Bone Loss via a Gut Microbiota-Bone Axis. | Wan X, Eguchi A, Murayama R, Mori C, Hashimoto K. | Clin Psychopharmacol Neurosci | 10.9758/cpn.25.1309 | 2025 | ||
| Association Between Scalp Microbiota Imbalance, Disease Severity, and Systemic Inflammatory Markers in Alopecia Areata. | Gomez-Arias PJ, Gay-Mimbrera J, Rivera-Ruiz I, Aguilar-Luque M, Juan-Cencerrado M, Mochon-Jimenez C, Gomez-Garcia F, Sanchez-Gonzalez S, Ortega-Hernandez A, Gomez-Garre D, Parra-Peralbo E, Isla-Tejera B, Ruano J. | Dermatol Ther (Heidelb) | 10.1007/s13555-024-01281-2 | 2024 | ||
| Elucidating the functions of gut microbiota from two edible dung beetle species: Implications for waste management and food industry. | Mwanza SS, Mudalungu CM, Makwatta J, Kabii J, Kimani NM, Tanga CM. | PLoS One | 10.1371/journal.pone.0325756 | 2025 | ||
| Comparative Analysis of Gut Microbiomes in Laboratory Chinchillas, Ferrets, and Marmots: Implications for Pathogen Infection Research. | Guo J, Shi W, Li X, Yang B, Qin C, Su L. | Microorganisms | 10.3390/microorganisms12040646 | 2024 | ||
| Evaluation of the Impact of BaP Exposure on the Gut Microbiota and Allergic Responses in an OVA-Sensitized Mouse Model. | Du B, Xiao X, Wang H, Li W, Xia Z, Yang P, Huang SK, Yuan R, Liu J, Han M, Zou Y, Zhu J, He D, Lyu J, Jin X, Xu X, Wang J, Yang H, Xiao L, Liu X, Kristiansen K. | Environ Health Perspect | 10.1289/ehp11874 | 2023 | ||
| Apple polysaccharide improves age-matched cognitive impairment and intestinal aging through microbiota-gut-brain axis. | Zhang W, Zhong Y, Wang Z, Tang F, Zheng C. | Sci Rep | 10.1038/s41598-024-67132-4 | 2024 | ||
| Genetics | A multi-omics approach to overeating and inactivity-induced muscle atrophy in db/db mice. | Okamura T, Hamaguchi M, Kobayashi G, Ichikawa T, Hasegawa Y, Miyoshi T, Senmaru T, Nakanishi N, Sasano R, Fukui M. | J Cachexia Sarcopenia Muscle | 10.1002/jcsm.13550 | 2024 | |
| The Effect of Exogenous Bile Acids on Antioxidant Status and Gut Microbiota in Heat-Stressed Broiler Chickens. | Yin C, Xia B, Tang S, Cao A, Liu L, Zhong R, Chen L, Zhang H. | Front Nutr | 10.3389/fnut.2021.747136 | 2021 | ||
| Benzo(a)pyrene and Gut Microbiome Crosstalk: Health Risk Implications. | Mauliasari IR, Lee HJ, Koo SY, Hitayezu E, Kieu ANT, Lee SM, Cha KH. | Toxics | 10.3390/toxics12120938 | 2024 | ||
| Phylogeny | Mucosal Microbiome in Patients with Early Bowel Polyps: Inferences from Short-Read and Long-Read 16S rRNA Sequencing. | Welham Z, Li J, Engel AF, Molloy MP. | Cancers (Basel) | 10.3390/cancers15205045 | 2023 | |
| A probiotic for preventing microplastic toxicity: Clostridium dalinum mitigates microplastic-induced damage via microbiota-metabolism-barrier interactions. | Zheng-Qiang L, Jun L, Rui A, Rui L, Wei D, Ping M, Xu Y, Rong S, Xiao-Yan Y, Wen X. | Curr Res Food Sci | 10.1016/j.crfs.2025.101200 | 2025 | ||
| Metabolism | Plasma sphingolipids mediate the association between gut microbiome composition and type 2 diabetes risk in the HELIUS cohort: a case-cohort study. | Overbeek MF, Rutters F, Nieuwdorp M, Davids M, van Valkengoed I, Galenkamp H, van den Born BJ, Beulens JWJ, Muilwijk M. | BMJ Open Diabetes Res Care | 10.1136/bmjdrc-2024-004180 | 2024 | |
| Fecal microbiota transplantation from patients with rheumatoid arthritis causes depression-like behaviors in mice through abnormal T cells activation. | Pu Y, Zhang Q, Tang Z, Lu C, Wu L, Zhong Y, Chen Y, Hashimoto K, Luo Y, Liu Y. | Transl Psychiatry | 10.1038/s41398-022-01993-z | 2022 | ||
| Metabolism | Treatment-Related Mechanisms of Tibetan Medicine Terminalia chebula (TC) Aqueous Extract Against Mouse Gastroenteritis Caused by Yak-Origin Salmonella Determined Using Intestinal Microbiome Analysis and Metabolomics. | Li D, Zhang K, Xue X, Bai Z, Yang, Qi J, Suolang S. | Animals (Basel) | 10.3390/ani15050755 | 2025 | |
| Dysregulated Immunity to Clostridioides difficile in IBD Patients Without a History of Recognized Infection. | Cook L, Wong MQ, Rees WD, Schick A, Lisko DJ, Lunken GR, Wang X, Peters H, Oliveira L, Lau T, Mah R, Bressler B, Levings MK, Steiner TS. | Inflamm Bowel Dis | 10.1093/ibd/izad238 | 2024 | ||
| Genetics | Shotgun metagenomics reveals interkingdom association between intestinal bacteria and fungi involving competition for nutrients. | Xie Z, Canalda-Baltrons A, d'Enfert C, Manichanh C. | Microbiome | 10.1186/s40168-023-01693-w | 2023 | |
| The Combination of Lead and Bacillus coagulans R11 Increased the Concentration of Alpha-Solanine in the Cecum of Laying Hens and the Pathogens Abundance Decreased. | Xing SC, Chen JY, Chen YX, Wu RT, Huang CB, Zhang Y, Mi JD, Liao XD. | Front Microbiol | 10.3389/fmicb.2020.585197 | 2020 | ||
| Regulatory Effects of Combined Dietary Supplementation With Essential Oils and Organic Acids on Microbial Communities of Cobb Broilers. | Qiao J, Shang Z, Liu X, Wang K, Wu Z, Wei Q, Li H. | Front Microbiol | 10.3389/fmicb.2021.814626 | 2021 | ||
| Characterization of the gut microbiota and fecal and blood metabolomes under various factors in urban children from Northwest China. | Yang Y, Chen J, Gao H, Cui M, Zhu M, Xiang X, Wang Q. | Front Cell Infect Microbiol | 10.3389/fcimb.2024.1374544 | 2024 | ||
| Pretreatment with an antibiotics cocktail enhances the protective effect of probiotics by regulating SCFA metabolism and Th1/Th2/Th17 cell immune responses. | Xu J, Xu H, Guo X, Zhao H, Wang J, Li J, He J, Huang H, Huang C, Zhao C, Li Y, Zhou Y, Peng Y, Nie Y. | BMC Microbiol | 10.1186/s12866-024-03251-2 | 2024 | ||
| Genetics | Decoding the diagnostic and therapeutic potential of microbiota using pan-body pan-disease microbiomics. | Schmartz GP, Rehner J, Gund MP, Keller V, Molano LG, Rupf S, Hannig M, Berger T, Flockerzi E, Seitz B, Fleser S, Schmitt-Grohe S, Kalefack S, Zemlin M, Kunz M, Gotzinger F, Gevaerd C, Vogt T, Reichrath J, Diehl L, Hecksteden A, Meyer T, Herr C, Gurevich A, Krug D, Hegemann J, Bozhueyuek K, Gulder TAM, Fu C, Beemelmanns C, Schattenberg JM, Kalinina OV, Becker A, Unger M, Ludwig N, Seibert M, Stein ML, Hanna NL, Martin MC, Mahfoud F, Krawczyk M, Becker SL, Muller R, Bals R, Keller A. | Nat Commun | 10.1038/s41467-024-52598-7 | 2024 | |
| Metabolism | The dynamics of the gut microbiota in prediabetes during a four-year follow-up among European patients-an IMI-DIRECT prospective study. | Lyu L, Fan Y, Vogt JK, Clos-Garcia M, Bonnefond A, Pedersen HK, Dutta A, Koivula R, Sharma S, Allin KH, Brorsson C, Cederberg H, Chabanova E, De Masi F, Dermitzakis E, Elders PJ, Blom MT, Hollander M, Eriksen R, Forgie I, Frost G, Giordano GN, Grallert H, Haid M, Hansen TH, Jablonka B, Kokkola T, Mahajan A, Mari A, McDonald TJ, Musholt PB, Pavo I, Prehn C, Ridderstrale M, Ruetten H, Hart LM', Schwenk JM, Stankevic E, Thomsen HS, Vangipurapu J, Vestergaard H, Vinuela A, Walker M, Hansen T, Linneberg A, Nielsen HB, Brunak S, McCarthy MI, Froguel P, Adamski J, Franks PW, Laakso M, Beulens JWJ, Pearson E, Pedersen O. | Genome Med | 10.1186/s13073-025-01508-7 | 2025 | |
| Human Gut Microbiota for Diagnosis and Treatment of Depression. | Averina OV, Poluektova EU, Zorkina YA, Kovtun AS, Danilenko VN. | Int J Mol Sci | 10.3390/ijms25115782 | 2024 | ||
| Novel role of FTO in regulation of gut-brain communication via Desulfovibrio fairfieldensis-produced hydrogen sulfide under arsenic exposure. | Chen R, Chai X, Zhang Y, Zhou T, Xia Y, Jiang X, Lv B, Zhang J, Zhou L, Tian X, Wang R, Mao L, Zhao F, Zhang H, Hu J, Qiu J, Zou Z, Chen C. | Gut Microbes | 10.1080/19490976.2024.2438471 | 2025 | ||
| Phylogeny | Comparison between 16S rRNA and shotgun sequencing in colorectal cancer, advanced colorectal lesions, and healthy human gut microbiota. | Bars-Cortina D, Ramon E, Rius-Sansalvador B, Guino E, Garcia-Serrano A, Mach N, Khannous-Lleiffe O, Saus E, Gabaldon T, Ibanez-Sanz G, Rodriguez-Alonso L, Mata A, Garcia-Rodriguez A, Obon-Santacana M, Moreno V. | BMC Genomics | 10.1186/s12864-024-10621-7 | 2024 | |
| Lactiplantibacillus plantarum, lactiplantibacillus pentosus and inulin meal inclusion boost the metagenomic function of broiler chickens. | Ferrocino I, Biasato I, Dabbou S, Colombino E, Rantsiou K, Squara S, Gariglio M, Capucchio MT, Gasco L, Cordero CE, Liberto E, Schiavone A, Cocolin L. | Anim Microbiome | 10.1186/s42523-023-00257-5 | 2023 | ||
| The Genus Alistipes: Gut Bacteria With Emerging Implications to Inflammation, Cancer, and Mental Health. | Parker BJ, Wearsch PA, Veloo ACM, Rodriguez-Palacios A. | Front Immunol | 10.3389/fimmu.2020.00906 | 2020 | ||
| Perturbed gut microbiome and fecal and serum metabolomes are associated with chronic kidney disease severity. | Wang H, Ainiwaer A, Song Y, Qin L, Peng A, Bao H, Qin H. | Microbiome | 10.1186/s40168-022-01443-4 | 2023 | ||
| Proteome | Insights into the proteomic profile of newly harvested corn and metagenomic analysis of the broiler intestinal microbiota. | Yin D, Wang Y, Wang L, Wu Y, Bian X, Aggrey SE, Yuan J. | J Anim Sci Biotechnol | 10.1186/s40104-021-00656-1 | 2022 | |
| Effects of Yulin Tong Bu formula on modulating gut microbiota and fecal metabolite interactions in mice with polycystic ovary syndrome. | Su YN, Wang MJ, Yang JP, Wu XL, Xia M, Bao MH, Ding YB, Feng Q, Fu LJ. | Front Endocrinol (Lausanne) | 10.3389/fendo.2023.1122709 | 2023 | ||
| Male-Biased Gut Microbiome and Metabolites Aggravate Colorectal Cancer Development. | Wang L, Tu YX, Chen L, Zhang Y, Pan XL, Yang SQ, Zhang SJ, Li SH, Yu KC, Song S, Xu HL, Yin ZC, Yue JQ, Ni QL, Tang T, Zhang JL, Guo M, Zhang S, Yao F, Liang XJ, Chen ZX. | Adv Sci (Weinh) | 10.1002/advs.202206238 | 2023 | ||
| Metabolism | Quercetin metabolism by fecal microbiota from healthy elderly human subjects. | Tamura M, Hoshi C, Kobori M, Takahashi S, Tomita J, Nishimura M, Nishihira J. | PLoS One | 10.1371/journal.pone.0188271 | 2017 | |
| Metabolism | Synbiotic-driven improvement of metabolic disturbances is associated with changes in the gut microbiome in diet-induced obese mice. | Ke X, Walker A, Haange SB, Lagkouvardos I, Liu Y, Schmitt-Kopplin P, von Bergen M, Jehmlich N, He X, Clavel T, Cheung PCK. | Mol Metab | 10.1016/j.molmet.2019.01.012 | 2019 | |
| Phylogeny | Alistipes inops sp. nov. and Coprobacter secundus sp. nov., isolated from human faeces. | Shkoporov AN, Chaplin AV, Khokhlova EV, Shcherbakova VA, Motuzova OV, Bozhenko VK, Kafarskaia LI, Efimov BA. | Int J Syst Evol Microbiol | 10.1099/ijsem.0.000617 | 2015 |
| #20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 ) |
| #42732 | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 28863 |
| #67770 | Japan Collection of Microorganism (JCM) ; Curators of the JCM; |
| #68380 | Automatically annotated from API rID32A . |
| #125439 | Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 . |
| #126262 | A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 ) |
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