Nocardia farcinica S738 is an obligate aerobe, mesophilic, Gram-positive human pathogen of the family Nocardiaceae.
Gram-positive rod-shaped obligate aerobe mesophilic human pathogen 16S sequence| @ref 20215 |
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| Domain Bacteria |
| Phylum Actinomycetota |
| Class Actinomycetes |
| Order Mycobacteriales |
| Family Nocardiaceae |
| Genus Nocardia |
| Species Nocardia farcinica |
| Full scientific name Nocardia farcinica Trevisan 1889 (Approved Lists 1980) |
| @ref | Gram stain | Cell shape | Motility | |
|---|---|---|---|---|
| 119284 | positive | rod-shaped |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 10931 | GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) | Medium recipe at MediaDive | Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water | ||
| 35736 | MEDIUM 3 - Columbia agar | Columbia agar (39.000 g);distilled water (1000.000 ml) | |||
| 119284 | CIP Medium 3 | Medium recipe at CIP |
| 119284 | Oxygen toleranceobligate aerobe |
| 67770 | Observationquinones: MK-8(H4) |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68371 | 27613 ChEBI | amygdalin | - | builds acid from | from API 50CH acid |
| 68371 | 18305 ChEBI | arbutin | - | builds acid from | from API 50CH acid |
| 68371 | 17057 ChEBI | cellobiose | - | builds acid from | from API 50CH acid |
| 119284 | 16947 ChEBI | citrate | - | carbon source | |
| 68371 | 17108 ChEBI | D-arabinose | - | builds acid from | from API 50CH acid |
| 68371 | 18333 ChEBI | D-arabitol | - | builds acid from | from API 50CH acid |
| 68371 | 15824 ChEBI | D-fructose | - | builds acid from | from API 50CH acid |
| 68371 | 28847 ChEBI | D-fucose | - | builds acid from | from API 50CH acid |
| 68371 | 12936 ChEBI | D-galactose | - | builds acid from | from API 50CH acid |
| 68371 | 17634 ChEBI | D-glucose | - | builds acid from | from API 50CH acid |
| 68371 | 62318 ChEBI | D-lyxose | - | builds acid from | from API 50CH acid |
| 68371 | 16899 ChEBI | D-mannitol | - | builds acid from | from API 50CH acid |
| 68371 | 16024 ChEBI | D-mannose | - | builds acid from | from API 50CH acid |
| 68371 | 16988 ChEBI | D-ribose | - | builds acid from | from API 50CH acid |
| 68371 | 17924 ChEBI | D-sorbitol | - | builds acid from | from API 50CH acid |
| 68371 | 16443 ChEBI | D-tagatose | - | builds acid from | from API 50CH acid |
| 68371 | 65327 ChEBI | D-xylose | - | builds acid from | from API 50CH acid |
| 68371 | 17113 ChEBI | erythritol | - | builds acid from | from API 50CH acid |
| 119284 | 4853 ChEBI | esculin | + | hydrolysis | |
| 68371 | 4853 ChEBI | esculin | - | builds acid from | from API 50CH acid |
| 68371 | 16813 ChEBI | galactitol | - | builds acid from | from API 50CH acid |
| 68371 | 28066 ChEBI | gentiobiose | - | builds acid from | from API 50CH acid |
| 68371 | 24265 ChEBI | gluconate | - | builds acid from | from API 50CH acid |
| 68371 | 17754 ChEBI | glycerol | - | builds acid from | from API 50CH acid |
| 68371 | 28087 ChEBI | glycogen | - | builds acid from | from API 50CH acid |
| 119284 | 606565 ChEBI | hippurate | + | hydrolysis | |
| 68371 | 15443 ChEBI | inulin | - | builds acid from | from API 50CH acid |
| 68371 | 30849 ChEBI | L-arabinose | - | builds acid from | from API 50CH acid |
| 68371 | 18403 ChEBI | L-arabitol | - | builds acid from | from API 50CH acid |
| 68371 | 18287 ChEBI | L-fucose | - | builds acid from | from API 50CH acid |
| 68371 | 62345 ChEBI | L-rhamnose | - | builds acid from | from API 50CH acid |
| 68371 | 17266 ChEBI | L-sorbose | - | builds acid from | from API 50CH acid |
| 68371 | 65328 ChEBI | L-xylose | - | builds acid from | from API 50CH acid |
| 68371 | 17716 ChEBI | lactose | - | builds acid from | from API 50CH acid |
| 68371 | 17306 ChEBI | maltose | - | builds acid from | from API 50CH acid |
| 68371 | 6731 ChEBI | melezitose | - | builds acid from | from API 50CH acid |
| 68371 | 28053 ChEBI | melibiose | - | builds acid from | from API 50CH acid |
| 68371 | 320061 ChEBI | methyl alpha-D-glucopyranoside | - | builds acid from | from API 50CH acid |
| 68371 | 43943 ChEBI | methyl alpha-D-mannoside | - | builds acid from | from API 50CH acid |
| 68371 | 74863 ChEBI | methyl beta-D-xylopyranoside | - | builds acid from | from API 50CH acid |
| 68371 | 17268 ChEBI | myo-inositol | - | builds acid from | from API 50CH acid |
| 68371 | 59640 ChEBI | N-acetylglucosamine | - | builds acid from | from API 50CH acid |
| 119284 | 17632 ChEBI | nitrate | - | reduction | |
| 119284 | 17632 ChEBI | nitrate | - | respiration | |
| 119284 | 16301 ChEBI | nitrite | - | reduction | |
| 68371 | Potassium 2-ketogluconate | - | builds acid from | from API 50CH acid | |
| 68371 | Potassium 5-ketogluconate | - | builds acid from | from API 50CH acid | |
| 68371 | 16634 ChEBI | raffinose | - | builds acid from | from API 50CH acid |
| 68371 | 15963 ChEBI | ribitol | - | builds acid from | from API 50CH acid |
| 68371 | 17814 ChEBI | salicin | - | builds acid from | from API 50CH acid |
| 68371 | 28017 ChEBI | starch | - | builds acid from | from API 50CH acid |
| 68371 | 17992 ChEBI | sucrose | - | builds acid from | from API 50CH acid |
| 68371 | 27082 ChEBI | trehalose | - | builds acid from | from API 50CH acid |
| 68371 | 32528 ChEBI | turanose | - | builds acid from | from API 50CH acid |
| 68371 | 17151 ChEBI | xylitol | - | builds acid from | from API 50CH acid |
| @ref | Metabolite | Is sensitive | Is resistant | |
|---|---|---|---|---|
| 119284 | 0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate) |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 119284 | alcohol dehydrogenase | - | 1.1.1.1 | |
| 68382 | alkaline phosphatase | - | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | + | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 119284 | amylase | + | ||
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 119284 | beta-galactosidase | + | 3.2.1.23 | |
| 68382 | beta-glucosidase | + | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 119284 | caseinase | - | 3.4.21.50 | |
| 119284 | catalase | + | 1.11.1.6 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 68382 | esterase (C 4) | + | from API zym | |
| 68382 | esterase lipase (C 8) | + | from API zym | |
| 119284 | gamma-glutamyltransferase | - | 2.3.2.2 | |
| 119284 | gelatinase | + | ||
| 119284 | lecithinase | - | ||
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 119284 | lipase | - | ||
| 68382 | lipase (C 14) | - | from API zym | |
| 119284 | lysine decarboxylase | - | 4.1.1.18 | |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 119284 | ornithine decarboxylase | - | 4.1.1.17 | |
| 119284 | oxidase | - | ||
| 119284 | phenylalanine ammonia-lyase | - | 4.3.1.24 | |
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 119284 | tryptophan deaminase | - | ||
| 119284 | tween esterase | - | ||
| 119284 | urease | - | 3.5.1.5 | |
| 68382 | valine arylamidase | - | from API zym |
| @ref | ControlQ | GLY | ERY | DARA | LARA | RIB | DXYL | LXYL | ADO | MDX | GAL | GLU | FRU | MNE | SBE | RHA | DUL | INO | MAN | SOR | MDM | MDG | NAG | AMY | ARB | ESC | SAL | CEL | MAL | LAC | MEL | SAC | TRE | INU | MLZ | RAF | AMD | GLYG | XLT | GEN | TUR | LYX | TAG | DFUC | LFUC | DARL | LARL | GNT | 2KG | 5KG | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 119284 | not determinedn.d. | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 20218 | Nocardia farcinica strain DSM 43289 note copy 1 rrnC operon, partial sequence; and 16S-23S ribosomal RNA intergenic spacer, complete sequence | AF536441 | 345 | 37329 | ||
| 20218 | Nocardia farcinica strain DSM 43289 note copy 2 16S-23S ribosomal RNA intergenic spacer, complete sequence | AF536442 | 334 | 37329 | ||
| 20218 | Nocardia farcinica strain DSM 43289 note copy 3 rrnA operon, partial sequence; and 16S-23S ribosomal RNA intergenic spacer, complete sequence | AF536443 | 327 | 37329 | ||
| 20218 | Nocardia farcinica strain DSM 43289 16S ribosomal RNA gene, partial sequence | JN041681 | 462 | 37329 | ||
| 124043 | Nocardia farcinica strain DSM 43289 16S ribosomal RNA gene, partial sequence. | KR265283 | 386 | 37329 |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Transcriptome | Case report: Pathology, antimicrobial resistance, and molecular characterization of bovine abortion cases caused by Nocardia farcinica in Korean native cattle. | Kim EM, Yun CS, Bae YC, Lee H, Moon BY, Lee K, Jeoung HY, Ku BK, Kim J. | Front Vet Sci | 10.3389/fvets.2024.1407634 | 2024 | |
| Nocardia farcinica activates human dendritic cells and induces secretion of interleukin-23 (IL-23) rather than IL-12p70. | Eisenblatter M, Buchal A, Gayum H, Jasny E, Renner Viveros P, Ulrichs T, Schneider T, Schumann RR, Zweigner J, Ignatius R. | Infect Immun | 10.1128/iai.00741-12 | 2012 | ||
| Phylogeny | Identification of pathogenic Nocardia species by reverse line blot hybridization targeting the 16S rRNA and 16S-23S rRNA gene spacer regions. | Xiao M, Kong F, Sorrell TC, Cao Y, Lee OC, Liu Y, Sintchenko V, Chen SC. | J Clin Microbiol | 10.1128/jcm.01761-09 | 2010 | |
| Phylogeny | secA1 gene sequence polymorphisms for species identification of Nocardia species and recognition of intraspecies genetic diversity. | Kong F, Wang H, Zhang E, Sintchenko V, Xiao M, Sorrell TC, Chen X, Chen SC. | J Clin Microbiol | 10.1128/jcm.01113-10 | 2010 | |
| Enzymology | Isolation of Nocardia paucivorans from the cerebrospinal fluid of a patient with relapse of cerebral nocardiosis. | Eisenblatter M, Disko U, Stoltenburg-Didinger G, Scherubl H, Schaal KP, Roth A, Ignatius R, Zeitz M, Hahn H, Wagner J. | J Clin Microbiol | 10.1128/jcm.40.9.3532-3534.2002 | 2002 | |
| Phylogeny | Assignment of reference 5'-end 16S rDNA sequences and species-specific sequence polymorphisms improves species identification of Nocardia. | Kong F, Chen SC, Chen X, Sintchenko V, Halliday C, Cai L, Tong Z, Lee OC, Sorrell TC. | Open Microbiol J | 10.2174/1874285800903010097 | 2009 | |
| Pathogenicity | Cefotaxime-resistant Nocardia asteroides strains are isolates of the controversial species Nocardia farcinica. | Wallace RJ, Tsukamura M, Brown BA, Brown J, Steingrube VA, Zhang YS, Nash DR. | J Clin Microbiol | 10.1128/jcm.28.12.2726-2732.1990 | 1990 | |
| Enzymology | Partial characterization of Nocardia farcinica beta-lactamases. | Steingrube VA, Wallace RJ, Brown BA, Zhang Y, Steele LC, Young G, Nash DR. | Antimicrob Agents Chemother | 10.1128/aac.37.9.1850 | 1993 | |
| Enzymology | Sequence-based identification of aerobic actinomycetes. | Patel JB, Wallace RJ, Brown-Elliott BA, Taylor T, Imperatrice C, Leonard DG, Wilson RW, Mann L, Jost KC, Nachamkin I. | J Clin Microbiol | 10.1128/jcm.42.6.2530-2540.2004 | 2004 | |
| Phylogeny | Fatty acid characterization of rapidly growing pathogenic aerobic actinomycetes as a means of identification. | McNabb A, Shuttleworth R, Behme R, Colby WD. | J Clin Microbiol | 10.1128/jcm.35.6.1361-1368.1997 | 1997 | |
| Enzymology | Use of PCR and reverse line blot hybridization macroarray based on 16S-23S rRNA gene internal transcribed spacer sequences for rapid identification of 34 mycobacterium species. | Xiong L, Kong F, Yang Y, Cheng J, Gilbert GL. | J Clin Microbiol | 10.1128/jcm.00633-06 | 2006 | |
| Phylogeny | Clinical and laboratory features of the Nocardia spp. based on current molecular taxonomy. | Brown-Elliott BA, Brown JM, Conville PS, Wallace RJ. | Clin Microbiol Rev | 10.1128/cmr.19.2.259-282.2006 | 2006 |
| #10931 | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 43289 |
| #20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 ) |
| #20218 | Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 ) |
| #35736 | ; Curators of the CIP; |
| #67770 | Japan Collection of Microorganism (JCM) ; Curators of the JCM; |
| #68371 | Automatically annotated from API 50CH acid . |
| #68382 | Automatically annotated from API zym . |
| #119284 | Collection of Institut Pasteur ; Curators of the CIP; CIP 104821 |
| #124042 | Johannes Wittmann, Clara Rolland, Lorenz Reimer, Joaquim Sardà: PhageDive . |
| #124043 | Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy . |
| #126262 | A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 ) |
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