Streptomyces antimycoticus (DSM 40284, ATCC 23880, CBS 660.68)

Name: Streptomyces antimycoticus (DSM 40284, ATCC 23880, CBS 660.68)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 14991

Type strain

Culture col. no. DSM 40284 ATCC 23880 CBS 660.68 IFO 12839 ISP 5284 12 more

NCBI tax ID(s) 68175

Special Collections DSMZ JCM KCTC Wink compendium

History <- E.B. Shirling, ISP <- NRRL KCC S-0228 <-- Y. Okami <-- ISP 5284 <-- NRRL 2421.

Links

Streptomyces antimycoticus DSM 40284 is a spore-forming bacterium that builds an aerial mycelium and produces antibiotic compounds.

antibiotic compound production spore-forming genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 38280

ATCC 23880,IFO 12839,DSM 40284,JCM 4228,NRRL 2421,JCM 4621,VKM Ac-1824,CBS 660.68,KCTC 9694,KCTC 9775,AS 4.1591,NBRC 12839,BCRC 15131,CCRC 15131,NBIMCC 1034,CGMCC 4.1591

@ref 20215

Last LPSN update 2026-02-09 11:21:34

Domain Bacteria

Phylum Actinomycetota

Class Actinomycetes

Order Kitasatosporales

Family Streptomycetaceae

Genus Streptomyces

Species Streptomyces antimycoticus

Full scientific name Streptomyces antimycoticus Waksman 1957 (Approved Lists 1980)

BacDive ID	Other strains from **Streptomyces antimycoticus** (1)	Type strain
16195	S. antimycoticus DSM 41461, ATCC 43693, INMI 97, VKM Ac-315, ...

Morphology

Cell morphology

@ref	Confidence	Gram stain
125438	90.5
125439	99.8	positive
125439	93.1

Colony morphology

@ref	Colony color	Incubation period	Medium used
19432	Yellow	10-14 days	ISP 2
19432	Yellow	10-14 days	ISP 3
19432	Yellow	10-14 days	ISP 4
19432	Yellow	10-14 days	ISP 5
19432	Yellow	10-14 days	ISP 6
19432	Yellow	10-14 days	ISP 7

Multicellular morphology

@ref	Complex name	Complex color	Medium name
19432	Aerial Mycelium	Grey	ISP 2
19432	Aerial Mycelium	Grey	ISP 3
19432	Aerial Mycelium	Grey	ISP 4
19432	Aerial Mycelium	Grey	ISP 5
19432	Aerial Mycelium	Grey	ISP 6
19432	Aerial Mycelium	Grey	ISP 7

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
9435	GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)	Medium recipe at MediaDive	Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water
19432	ISP 2		Name: ISP 2 / Yeast Malt Agar (5265); 5265 Composition Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l Agar 15.0 g/l Preparation: Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.0 Usage: Maintenance and Taxonomy Organisms: All Actinomycetes
19432	ISP 3		Name: ISP 3; 5315 Composition Dog oat flakes 20.0 g/l Trace element solution (5314) 2.5 ml/l Agar 18.0 g/l Preparation: Oat flakes are cooked for 20 minutes, trace element solution and agar are added (in the case of non rolled oat flakes the suspension has to bee filtrated). Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.8 Usage: Maintenance and taxonomy (e.g. SEM As liquid medium for metabolite production) Organisms: All Actinomycetes Trace element solution 5314 Name: Trace element solution 5314; 5314 Composition CaCl2 x H2O 3.0 g/l Fe-III-citrate 1.0 g/l MnSO4 0.2 g/l ZnCl2 0.1 g/l CuSO4 x 5 H2O 0.025 g/l Sodium tetra borate 0.2 g/l CoCl2 x 6 H2O 0.004 g/l Sodium molybdate 0.01 g/l Preparation: Use double destillated water. Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Trace element solution for different media Organisms:
19432	ISP 4		Name: ISP 4; DSM 547 Solution I: Difco soluble starch, 10.0 g. Make a paste of the starch with a small amount of cold distilled water and bring to a volume of 500 ml. Solution II: CaCO3 2.0 g K2HPO4 (anhydrous) 1.0 g MgSO4 x 7 H2O 1.0 g NaCl 1.0 g (NH4)2SO4 2.0 g Distilled water 500.0 ml Trace salt solution (see below) 1.0 ml The pH should be between 7.0 and 7.4. Do not adjust if it is within this range. Mix solutions I and II together. Add 20.0 g agar. Liquify agar by steaming at 100°C for 10 to 20 min. Trace element solution: FeSO4 x 7 H2O 0.1 g MnCl2 x 4 H2O 0.1 g ZnSO4 x 7 H2O 0.1 g Distilled water 100.0 ml
19432	ISP 5		Name: ISP 5 (5323) Composition L-Asparagine 1.0 g/l Glycerol 10.0 g/l K2HPO4 1.0 g/l Salt solution (see preparation) 1.0 ml/l Agar 20.0 g/l Preparation: Salt solution 1.0 g FeSO4 x 7 H2O 1.0 g MnCl2 x 4 H2O 1.0 g ZNSO4 x 7 H2O in 100 ml water Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.2 Usage: Maintenance and taxonomy Organisms: All Actinomycetes
19432	ISP 6		Name: ISP 6 (5318) Composition Peptone 15.0 g/l Proteose peptose 5.0 g/l Ferric ammonium citrate 0.5 g/l Sodium glycerophosphate 1.0 g/l Sodium thiosulfate 0.08 g/l Yeast extract 1.0 g/l Agar 15.0 g/l Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Production of melanoid pigments Organisms: All Actinomycetes
19432	ISP 7		Name: ISP 7 (5322) Composition Glycerol 15.0 g/l L-Tyrosine 0.5 g/l L-Asparagine 1.0 g/l K2HPO4 0.5 g/l NaCl 0.5 g/l FeSO4 x 7 H2O 0.01 g/l Trace element solution 5343 1.0 ml/l Agar 20.0 Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.3 Usage: Production of melanoid pigments Organisms: All Actinomycetes
9435	ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84)	Medium recipe at MediaDive	Name: ROLLED OATS MINERAL MEDIUM (DSMZ Medium 84) Composition: Agar 20.0 g/l Rolled oats 20.0 g/l ZnSO4 x 7 H2O 0.001 g/l MnCl2 x 4 H2O 0.001 g/l FeSO4 x 7 H2O 0.001 g/l Distilled water

Culture temp

@ref	Growth	Type	Temperature (°C)
9435	positive	growth	28
19432	positive	optimum	28
67770	positive	growth	28

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
125438	aerobe	91.467
125439	obligate aerobe	99

Spore formation

@ref	Spore description	Confidence
19432	Formation of spore chains: spira, spore surface: warty
125438		93.63
125439		93.6

Compound production

@ref	Compound
9435	endomycin complex (=helixin)
9435	helixin

Halophily

@ref	Salt	Growth	Tested relation	Concentration
19432	NaCl	positive	growth	0 %

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
19432	22599 ChEBI	arabinose	+
68368	29016 ChEBI	arginine	-	hydrolysis	from API 20E
19432	62968 ChEBI	cellulose	+
68368	16947 ChEBI	citrate	-	assimilation	from API 20E
19432	28757 ChEBI	fructose	+
68368	5291 ChEBI	gelatin	+	hydrolysis	from API 20E
19432	17234 ChEBI	glucose	+
68368	25094 ChEBI	lysine	-	degradation	from API 20E
19432	29864 ChEBI	mannitol	+
19432	17268 ChEBI	myo-inositol	+
68368	18257 ChEBI	ornithine	-	degradation	from API 20E
19432	16634 ChEBI	raffinose	+
19432	26546 ChEBI	rhamnose	+
19432	17992 ChEBI	sucrose	+
68368	27897 ChEBI	tryptophan	-	energy source	from API 20E
68368	16199 ChEBI	urea	+	hydrolysis	from API 20E
19432	18222 ChEBI	xylose	-

Metabolite production

@ref	Chebi-ID	Metabolite
68368	15688 ChEBI	acetoin	from API 20E
67770	69370 ChEBI	helixin
68368	16136 ChEBI	hydrogen sulfide	from API 20E
68368	35581 ChEBI	indole	from API 20E

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Indole test
68368	15688 ChEBI	acetoin	+		from API 20E
68368	35581 ChEBI	indole		-	from API 20E

Enzymes

@ref	Value	Activity	Ec
68368	arginine dihydrolase	-	3.5.3.6	from API 20E
68368	beta-galactosidase	-	3.2.1.23	from API 20E
68368	gelatinase	+		from API 20E
68368	lysine decarboxylase	-	4.1.1.18	from API 20E
68368	ornithine decarboxylase	-	4.1.1.17	from API 20E
68368	tryptophan deaminase	+	4.1.99.1	from API 20E
68368	urease	+	3.5.1.5	from API 20E

API 20E

@ref	ONPG	ADH (Arg)	LDC (Lys)	ODC	CIT	H2S productionH2S	URE	TDA (Trp)	IND	Acetoin production (Voges Proskauer test)VP	GEL	GLU	MAN	INO	Sor	RHA	SAC	MEL	AMY	ARA	OX	Nitrite productionNO2	Reduction to N2N2	MotilityMOB	Growth on MacConkey mediumMAC	OF-O	OF-F
19432	-	-	-	-	-	-	+	+	-	+	+	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Engineered	#Biodegradation	#Composting
#Environmental	#Terrestrial	#Soil

Isolation

@ref	Sample type
9435	composted soil
67770	Composted soil

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
9435	1	Risk group (German classification) According to TRBA 466
19432	1	Risk group (German classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
67770	ASM540592v1 assembly for Streptomyces antimycoticus NBRC 12839	contig	GCA_005405925	68175.3	8008525713	68175	71.34
124043	ASM4243084v1 assembly for Streptomyces antimycoticus JCM 4228	scaffold	GCA_042430845			68175	46.8
124043	ASM3953519v1 assembly for Streptomyces antimycoticus JCM 4228	contig	GCA_039535195			68175	41.97

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Streptomyces antimycoticus strain CGMCC 4.1591 16S ribosomal RNA gene, partial sequence	HQ244448	1381	68175
20218	Streptomyces antimycoticus gene for 16S rRNA, partial sequence	AB122752	565	68175
20218	Streptomyces antimycoticus gene for 16S ribosomal RNA, partial sequence, strain: JCM 4228	D44034	121	68175
20218	Streptomyces antimycoticus strain KCTC 9694 16S ribosomal RNA gene, partial sequence	AY999831	1423	68175
20218	Streptomyces antimycoticus gene for 16S rRNA, partial sequence, strain: NBRC 12839	AB184185	1478	68175
124043	Streptomyces antimycoticus strain JCM 4228 16S ribosomal RNA gene, partial sequence.	MT760497	1383	68175

GC content

@ref	GC-content (mol%)	Method
67770	71	genome sequence analysis

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Streptomyces antimycoticus NBRC 12839
NCBI: GCA_005405925

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	yes	93.60	no
125439	motility	BacteriaNetⓘ	no	93.10	no
125439	gram_stain	BacteriaNetⓘ	positive	99.80	no
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	99.00	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Streptomyces antimycoticus strain NBRC 12839
PATRIC: 68175.3

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	85.69	no
125438	anaerobic	anaerobicⓘ	no	95.48	no
125438	spore-forming	spore-formingⓘ	yes	93.63	yes
125438	thermophilic	thermophileⓘ	no	97.50	yes
125438	aerobic	aerobicⓘ	yes	91.47	no
125438	flagellated	motile2+ⓘ	no	90.50	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Validation List no. 224. Valid publication of new names and new combinations effectively published outside the IJSEM.	Oren A, Goker M.	Int J Syst Evol Microbiol	10.1099/ijsem.0.006801	2025
	Biotechnological and pharmaceutical potential of twenty-eight novel type strains of Actinomycetes from different environments worldwide.	Nouioui I, Boldt J, Zimmermann A, Makitrynskyy R, Potter G, Jando M, Doppner M, Kirstein S, Neumann-Schaal M, Gomez-Escribano JP, Nubel U, Mast Y.	Curr Res Microb Sci	10.1016/j.crmicr.2024.100290	2024
Phylogeny	Reclassification of Streptomyces castelarensis and Streptomyces sporoclivatus as later heterotypic synonyms of Streptomyces antimycoticus.	Komaki H, Tamura T	Int J Syst Evol Microbiol	10.1099/ijsem.0.003882	2020

References

#9435	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 40284
#19432	Wink, J.: Compendium of Actinobacteria. HZI-Helmholtz-Centre for Infection Research, Braunschweig .
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68368	Automatically annotated from API 20E .
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Streptomyces antimycoticus (DSM 40284, ATCC 23880, CBS 660.68)

Name and taxonomic classification

Morphology

Cell morphology

Colony morphology

Multicellular morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Compound production

Halophily

Metabolite utilization

Metabolite production

Metabolite tests

Enzymes

API 20E

Isolation, sampling and environmental information

Isolation source categories

Isolation

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_005405925

16S sequences

GC content

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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