Streptococcus sobrinus (DSM 20742, ATCC 33478, CCM 6070)

Name: Streptococcus sobrinus (DSM 20742, ATCC 33478, CCM 6070)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 14769

Type strain

Strain Designation SL1

Culture col. no. DSM 20742 ATCC 33478 CCM 6070 CCUG 25735 CAPM 6070 3 more

NCBI tax ID(s) 1123317 1310

Special Collections DSMZ CCUG CIP

History DSMZ <- ATCC; ATCC 33478 <- A. L. Coykendall; SL1 <- J. Tanzer; CIP <- 1988, NCFB <- 1983, ATCC <- A.L. Coykendall: strain SL1

Links

Streptococcus sobrinus SL1 is a microaerophile, Gram-positive, coccus-shaped bacterium that was isolated from human dental plaque.

Gram-positive coccus-shaped microaerophile genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 8082

LMG 14641,ATCC 33478,CCM 6070,CCRC 14757,CCUG 24717,CCUG 25735,CIP 103230,LMG 14642,NCFB 2724,NCDO 2724,NCIMB 702724,NCTC 12279,CECT 4010,BCRC 14757,HAMBI 1516,CNCTC 6715,VTT E-011804,DSM 20742

@ref 20215

Last LPSN update 2026-05-29 08:28:22

Domain Bacteria

Phylum Bacillota

Class Bacilli

Order Lactobacillales

Family Streptococcaceae

Genus Streptococcus

Species Streptococcus sobrinus

Full scientific name Streptococcus sobrinus (ex Coykendall 1974) Coykendall 1983

Synonyms (1)

"Streptococcus mutans subsp. sobrinus"

BacDive ID	Other strains from **Streptococcus sobrinus** (10)	Type strain
14768	S. sobrinus 25859, DSM 20381
135689	S. sobrinus CCUG 27644, CIP 74.16
143690	S. sobrinus CCUG 21019, ATCC 27351, NCTC 10921, CCM 7556
145042	S. sobrinus CCUG 27507, NCTC 11061
145283	S. sobrinus CCUG 28076
145284	S. sobrinus CCUG 28077
148341	S. sobrinus CCUG 35254
152127	S. sobrinus CCUG 45855 B
154039	S. sobrinus CCUG 52073
165122	S. sobrinus JCM 5176

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Motility	Confidence
125439	negative			92.433
122647	positive	coccus-shaped

Colony morphology

122647

Hemolysis ability1

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
9051	TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)	Medium recipe at MediaDive	Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water
39849	MEDIUM 38 - for Streptococcus and Gemella Haemolysans		Distilled water make up to (1000.000 ml);Horse serum (200.000 ml);Glucose (10.000 g);Brain heart infusion agar (52.000 g)
9051	COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)	Medium recipe at MediaDive	Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
122647	CIP Medium 38	Medium recipe at CIP
122647	CIP Medium 253	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
9051	positive	growth	37
39849	positive	growth	37

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
9051	microaerophile
122647	facultative anaerobe
125439	obligate aerobe	93.616

Spore formation

@ref	Spore formation	Confidence
125439		99.905

Murein

@ref	Murein short key	Type
9051	A11.25	A3alpha L-Lys-L-Thr-L-Ala

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68381	40585 ChEBI	alpha-cyclodextrin	-	builds acid from	from API rID32STR
68371	27613 ChEBI	amygdalin	-	builds acid from	from API 50CH acid
68371	18305 ChEBI	arbutin	-	builds acid from	from API 50CH acid
68381	29016 ChEBI	arginine	-	hydrolysis	from API rID32STR
68371	17057 ChEBI	cellobiose	-	builds acid from	from API 50CH acid
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68381	18333 ChEBI	D-arabitol	-	builds acid from	from API rID32STR
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	17634 ChEBI	D-glucose	+	builds acid from	from API 50CH acid
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68381	16899 ChEBI	D-mannitol	+	builds acid from	from API rID32STR
68371	16024 ChEBI	D-mannose	-	builds acid from	from API 50CH acid
68371	16988 ChEBI	D-ribose	-	builds acid from	from API 50CH acid
68371	16443 ChEBI	D-tagatose	+	builds acid from	from API 50CH acid
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
68371	4853 ChEBI	esculin	-	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68371	28066 ChEBI	gentiobiose	-	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	-	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
68381	28087 ChEBI	glycogen	-	builds acid from	from API rID32STR
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
68381	606565 ChEBI	hippurate	-	hydrolysis	from API rID32STR
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68381	30849 ChEBI	L-arabinose	-	builds acid from	from API rID32STR
68371	30849 ChEBI	L-arabinose	-	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68381	17716 ChEBI	lactose	+	builds acid from	from API rID32STR
68381	17306 ChEBI	maltose	+	builds acid from	from API rID32STR
68371	17306 ChEBI	maltose	+	builds acid from	from API 50CH acid
68381	6731 ChEBI	melezitose	-	builds acid from	from API rID32STR
68371	6731 ChEBI	melezitose	-	builds acid from	from API 50CH acid
68381	28053 ChEBI	melibiose	-	builds acid from	from API rID32STR
68371	28053 ChEBI	melibiose	-	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68381	320055 ChEBI	methyl beta-D-glucopyranoside	-	builds acid from	from API rID32STR
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
68371	59640 ChEBI	N-acetylglucosamine	-	builds acid from	from API 50CH acid
122647	17632 ChEBI	nitrate	-	reduction
122647	16301 ChEBI	nitrite	-	reduction
68371	0 ChEBI	Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371	0 ChEBI	Potassium 5-ketogluconate	+	builds acid from	from API 50CH acid
68381	27941 ChEBI	pullulan	-	builds acid from	from API rID32STR
68371	16634 ChEBI	raffinose	-	builds acid from	from API 50CH acid
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
68371	17814 ChEBI	salicin	-	builds acid from	from API 50CH acid
68371	28017 ChEBI	starch	+	builds acid from	from API 50CH acid
68381	17992 ChEBI	sucrose	+	builds acid from	from API rID32STR
68371	17992 ChEBI	sucrose	+	builds acid from	from API 50CH acid
68381	27082 ChEBI	trehalose	+	builds acid from	from API rID32STR
68371	27082 ChEBI	trehalose	+	builds acid from	from API 50CH acid
68371	32528 ChEBI	turanose	-	builds acid from	from API 50CH acid
68381	16199 ChEBI	urea	-	hydrolysis	from API rID32STR
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68381	15688 ChEBI	acetoin		from API rID32STR
122647	35581 ChEBI	indole

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test
68381	15688 ChEBI	acetoin	+	from API rID32STR

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
122647	alcohol dehydrogenase	-	1.1.1.1
68381	alkaline phosphatase	-	3.1.3.1	from API rID32STR
68382	alkaline phosphatase	-	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68381	alpha-galactosidase	-	3.2.1.22	from API rID32STR
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68381	arginine dihydrolase	-	3.5.3.6	from API rID32STR
68381	beta-galactosidase	-	3.2.1.23	from API rID32STR
68382	beta-galactosidase	-	3.2.1.23	from API zym
68382	beta-glucosidase	-	3.2.1.21	from API zym
68381	beta-glucuronidase	-	3.2.1.31	from API rID32STR
68382	beta-glucuronidase	-	3.2.1.31	from API zym
68381	beta-mannosidase	-	3.2.1.25	from API rID32STR
122647	catalase	-	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
68381	glycyl tryptophan arylamidase	-		from API rID32STR
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
122647	lysine decarboxylase	-	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68381	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API rID32STR
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
122647	ornithine decarboxylase	-	4.1.1.17
122647	oxidase	-
68381	pyrrolidonyl arylamidase	-	3.4.19.3	from API rID32STR
68382	trypsin	+	3.4.21.4	from API zym
68381	urease	-	3.5.1.5	from API rID32STR
122647	urease	-	3.5.1.5
68382	valine arylamidase	-		from API zym

Fatty acid profile

Metadata FA analysis

@ref

48255

Fatty acid	Percentage	ECL
C18:1 ω7c /12t/9t	28.1	17.824
C16:0	26.4	16
C20:1 ω9c	10.4	19.77
C18:1 ω9c	10.1	17.769
C18:0	6.7	18
C18:2 ω6,9c/C18:0 ANTE	6.5	17.724
C16:1 ω9c	4.3	15.774
C14:0	3.2	14
C16:1 ω7c	1.8	15.819
C16:1 ω5c	1	15.908
C20:1 ω7c	0.9	19.833
C18:1 ω5c	0.6	17.919

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
122647	-	-	+	+	-	+	-	-	+	-	+	+	-	-	-	+	-	-	-	-

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
122647	not determinedn.d.	-	-	-	-	-	-	-	-	-	+/-	+	+/-	-	-	-	-	-	+/-	+/-	-	-	-	-	-	-	-	-	+	+/-	-	+	+	-	-	-	+	-	-	-	-	-	+	-	-	-	-	-	-	+

API rID32STR

@ref	ADH (Arg)	beta GLU	beta GAR	beta GUR	alpha GAL	PAL	RIB	MAN	SOR	LAC	TRE	RAF	SAC	LARA	DARL	Acid from alpha-cyclodextrinCDEX	Acetoin production (Voges Proskauer test)VP	Alanyl-Phenylalanyl-Proline arylamidaseAPPA	beta GAL	Pyrrolidonyl arylamidasePyrA	N-Acetyl-glucosaminidasebeta NAG	Glycyl-tryptophan arylamidaseGTA	HIP	GLYG	PUL	MAL	MEL	MLZ	Acidification of methyl beta-D-glucopyranosideMbeta DG	TAG	beta MAN	URE
9051	-	-	-	-	-	-	-	+	-	+	+	-	+	-	-	-	+	+	-	-	-	-	-	-	-	+	-	-	-	-	-	-
9051	-	-	-	-	-	-	-	+	-	+	+	-	+	-	-	-	+	+	-	-	-	-	-	-	-	+	-	-	-	+	-	-
9051	-	-	-	-	-	-	+/-	+	+	+	+	-	+	-	-	-	+	+	-	-	-	-	-	-	-	+	-	-	-	+	-	-
9051	-	+/-	+/-	-	-	-	-	+	-	+	+	+	+	-	-	-	+	+/-	-	-	-	-	-	-	-	+	-	-	-	-	-	-
9051	-	-	-	-	-	-	-	+	-	+	+	-	+	-	-	-	+	+	-	-	-	-	-	-	-	+	-	-	-	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Host	#Human	-
#Host Body-Site	#Oral cavity and airways	#Plaque

Isolation

@ref	Sample type	Host species
9051	human dental plaque	Homo sapiens
48255	Human dental plaque	Homo sapiens
122647	Other, Dental plate

Taxonmaps

69479

Global distribution of 16S sequence NR_042773 (>99% sequence identity) for Streptococcus sobrinus subclade from Microbeatlas

Aquatic Samples	34
Soil Samples	44
Animal Samples	2137
Plant Samples	11
Total Samples	2226

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
9051	2	Risk group (German classification) According to TRBA 466
122647	2	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM317299v1 assembly for Streptococcus sobrinus SL1	complete	GCA_003172995	1310.6		1310	98.03
66792	ASM43904v1 assembly for Streptococcus sobrinus DSM 20742 = ATCC 33478	contig	GCA_000439045	1123317.4	2526164737	1123317	67.61
66792	ASM68660v1 assembly for Streptococcus sobrinus DSM 20742 = ATCC 33478	scaffold	GCA_000686605	1123317.5	2563366731	1123317	67.27
66792	DSM20742_V1 assembly for Streptococcus sobrinus DSM 20742 = ATCC 33478	contig	GCA_000347935	1123317.3	2534682312	1123317	0

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Streptococcus sobrinus strain ATCC 33478 16S ribosomal RNA gene, complete sequence	AY188349	1538	1310
20218	Streptococcus sobrinus strain ATCC 33478 16S ribosomal RNA gene, partial sequence; 16S-23S ribosomal RNA internal transcribed spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence	JN181392	643	1310
20218	Streptococcus sobrinus strain BCRC 14757 16S-23S ribosomal RNA intergenic spacer, partial sequence	DQ204560	443	1310
20218	S.sobrinus 16S rRNA	X58307	1334	1310
20218	Streptococcus sobrinus 16S rRNA gene, strain NCTC 12279	AJ243966	1459	1310
9051	Streptococcus sobrinus strain ATCC 33478 16S ribosomal RNA, partial sequence	NR_042773	1538	1310

GC content

9051

GC-content (mol%)45.1

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: ASM43904v1 assembly for Streptococcus sobrinus DSM 20742 = ATCC 33478
BV-BRC: 1123317.4

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	93.62	no
125439	gram_stain	BacteriaNetⓘ	negative	92.43	no
125439	motility	BacteriaNetⓘ	yes	44.79	no
125439	spore_formation	BacteriaNetⓘ	no	99.91	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Streptococcus sobrinus SL1
NCBI: GCA_003172995.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	88.11	no
125438	anaerobic	anaerobicⓘ	no	84.55	yes
125438	aerobic	aerobicⓘ	no	97.90	yes
125438	spore-forming	spore-formingⓘ	no	89.98	no
125438	thermophilic	thermophileⓘ	no	96.00	no
125438	flagellated	motile2+ⓘ	no	89.50	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Antibacterial Effect of Ozone on Cariogenic Bacteria and Its Potential Prejudicial Effect on Dentin Bond Strength-An In Vitro Study.	Santos M, Leandro F, Barroso H, Delgado AHS, Proenca L, Polido M, Vasconcelos E Cruz J.	Pharmaceutics	10.3390/pharmaceutics16050614	2024
	Influence of Different Bracket Adhesive Systems on Enamel Demineralization-An In Vitro Study.	Hennig CL, Lohnert S, Nitzsche A, Nietzsche S, Steiniger F, Marquetand J, Tolksdorf K, Guellmar A, Sigusch B, Jacobs C.	J Clin Med	10.3390/jcm12134494	2023
	The antibacterial effects of vitamin D3 against mutans streptococci: an in vitro study.	Almoudi MMM, Hussein AS, Abu Hassan MI, Al-Talib H, Khan HBSG, Nazli SAB, Effandy NAEB.	Eur Oral Res	10.26650/eor.20210119	2021
Metabolism	Effect of reduced nutritional supply on the metabolic activity and survival of cariogenic bacteria in vitro.	Ganas P, Schwendicke F.	J Oral Microbiol	10.1080/20002297.2019.1605788	2019
Genetics	Comparing the cariogenic species Streptococcus sobrinus and S. mutans on whole genome level.	Conrads G, de Soet JJ, Song L, Henne K, Sztajer H, Wagner-Dobler I, Zeng AP.	J Oral Microbiol	10.3402/jom.v6.26189	2014
Pathogenicity	Bacterial reduction in sealed caries lesions is strain- and material-specific.	Marggraf T, Ganas P, Paris S, Schwendicke F.	Sci Rep	10.1038/s41598-018-21842-8	2018
Transcriptome	Gene expression of bacterial collagenolytic proteases in root caries.	Dame-Teixeira N, Parolo CCF, Maltz M, Rup AG, Devine DA, Do T.	J Oral Microbiol	10.1080/20002297.2018.1424475	2018
	Preliminary screening of pomegranate-derived compounds for antimicrobial and anti-virulence effects against cariogenic streptococci.	Mohamad Zain N, Mohd Amin I, Abdul Razak F, Abu Hassan MI.	Saudi Dent J	10.1007/s44445-025-00083-2	2025
	The discovery of an anti-inflammatory monoterpenoid, neoroseoside from the Zea mays.	Tan H, Lee HJ, Hillman PF, Lee EY, Lee C, Seo EK, Lee MJ, Nam SJ.	Bioorg Med Chem Lett	10.1016/j.bmcl.2024.129737	2024
	Antibacterial activity of microwave synthesized hydroxyapatite against cariogenic bacteria: A preliminary study.	Ibrahim AZ, Hussein AS, Said Gulam Khan HB, Ghazali N.	Saudi Dent J	10.1016/j.sdentj.2024.06.004	2024
	Bifidobacterium animalis subsp. lactis HN019 has antimicrobial activity against endodontic pathogens in vitro.	Araujo LDC, da Silva RAB, Silva CMPC, Salvador SLS, Messora MR, Furlaneto FAC, Mastrange MDA, Pucinelli CM, da Silva LAB.	Braz J Microbiol	10.1007/s42770-023-01083-2	2023
	Comparison of biofilm models for producing artificial active white spot lesions.	Araujo EMDS, Vidal CMP, Zhu M, Banas JA, Freitas AZ, Wetter NU, Matos AB.	J Appl Oral Sci	10.1590/1678-7757-2023-0458	2024
	Antibacterial Activity of Fusidic Acid-Loaded Electrospun Polylactide Fiber Fleeces Against Periodontopathogenic Species.	Sigusch BW, Reise M, Kranz S, Beck J, Wagner K, Guellmar A, Heyder M.	Pharmaceutics	10.3390/pharmaceutics17070821	2025
	In Vitro and In Silico Studies of the Antimicrobial Activity of Prenylated Phenylpropanoids of Green Propolis and Their Derivatives against Oral Bacteria.	Vieira TM, Barco JG, de Souza SL, Santos ALO, Daoud I, Rahali S, Amdouni N, Bastos JK, Martins CHG, Ben Said R, Crotti AEM.	Antibiotics (Basel)	10.3390/antibiotics13080787	2024
	In-Vitro Effect of Manuka Honey / Propolis Toothpastes on Bacteria and Biofilm Associated with Caries and Gingivitis.	Jungbauer G, Lechner R, Stahli A, Sculean A, Eick S.	Oral Health Prev Dent	10.3290/j.ohpd.c_1910	2025
	Development of Antibacterial Resin Composites Incorporating Poly(METAC) Clusters.	Kohno T, Kitagawa H, Tsuboi R, Deng F, Sakai H, Wu T, Fan YS, Xiao L, Imazato S.	Materials (Basel)	10.3390/ma17040896	2024
	Compound Annotation by UHPLC-MS/MS, Quantification of Phenolic Compounds and Antimicrobial Activity of Monofloral Avocado Honey.	Sarmento TEC, de M Sacramento V, Brandao MM, de Melo Junior AF, Menezes EV, Veloso PHF, da C Pires N, Martins CHG, Calefi GG, A Alves TM, Caldeira ASP, Oliveira DA, Royo VA.	Plants (Basel)	10.3390/plants14213340	2025
	Polyalthic Acid from Copaifera lucens Demonstrates Anticariogenic and Antiparasitic Properties for Safe Use.	Santiago MB, Dos Santos VCO, Teixeira SC, Silva NBS, de Oliveira PF, Ozelin SD, Furtado RA, Tavares DC, Ambrosio SR, Veneziani RCS, Ferro EAV, Bastos JK, Martins CHG.	Pharmaceuticals (Basel)	10.3390/ph16101357	2023
	Antibacterial Properties of the Antimicrobial Peptide Gallic Acid-Polyphemusin I (GAPI).	Zhang OL, Niu JY, Yin IX, Yu OY, Mei ML, Chu CH.	Antibiotics (Basel)	10.3390/antibiotics12091350	2023
	Bovine Milk and Yogurt Affect Oral Microorganisms and Biofilms In-Vitro.	Tennert C, Sarra G, Stahli A, Sculean A, Eick S.	Oral Health Prev Dent	10.3290/j.ohpd.b3920023	2023
	Streptococcus sobrinus as a Predominant Oral Bacteria Related to the Occurrence of Dental Caries in Polish Children at 12 Years Old.	Korona-Glowniak I, Skawinska-Bednarczyk A, Wrobel R, Pietrak J, Tkacz-Ciebiera I, Maslanko-Switala M, Krawczyk D, Bakiera A, Borek A, Malm A, Mielnik-Blaszczak M.	Int J Environ Res Public Health	10.3390/ijerph192215005	2022
	The role of Lactobacillus plantarum in oral health: a review of current studies.	Huang X, Bao J, Yang M, Li Y, Liu Y, Zhai Y.	J Oral Microbiol	10.1080/20002297.2024.2411815	2024
	Magnesium Hydroxide Nanoparticles Inhibit the Biofilm Formation of Cariogenic Microorganisms.	Okamoto K, Kudo D, Phuong DND, Iwamoto Y, Watanabe K, Yoshioka Y, Ariyoshi W, Yamasaki R.	Nanomaterials (Basel)	10.3390/nano13050864	2023
	Dental adhesive microtensile bond strength following a biofilm-based in vitro aging model.	Jain A, Armstrong SR, Banas JA, Qian F, Maia RR, Teixeira EC.	J Appl Oral Sci	10.1590/1678-7757-2019-0737	2020
Phylogeny	Quantifying synthetic bacterial community composition with flow cytometry: efficacy in mock communities and challenges in co-cultures.	Mermans F, Chatzigiannidou I, Teughels W, Boon N.	mSystems	10.1128/msystems.01009-24	2025
	Anticariogenic Activity of Three Essential Oils from Brazilian Piperaceae.	Carvalho ES, Ayres VFS, Oliveira MR, Correa GM, Takeara R, Guimaraes AC, Santiago MB, Oliveira TAS, Martins CHG, Crotti AEM, Silva EO.	Pharmaceuticals (Basel)	10.3390/ph15080972	2022
	Synthesis, Antibacterial Effects, and Toxicity of Licochalcone C.	Ozanique PR, Helena AL, Menezes RP, Goncalves DS, Santiago MB, Dilarri G, Sardi JCO, Ferreira H, Martins CHG, Regasini LO.	Pharmaceuticals (Basel)	10.3390/ph17050634	2024
	Isolation and Typing of Streptococcus mutans and Streptococcus sobrinus from Caries-active Subjects.	Salman HA, Senthilkumar R, Imran K, Selvam KP.	Contemp Clin Dent	10.4103/ccd.ccd_610_17	2017
Enzymology	Improved method for rapid and accurate isolation and identification of Streptococcus mutans and Streptococcus sobrinus from human plaque samples.	Villhauer AL, Lynch DJ, Drake DR.	J Microbiol Methods	10.1016/j.mimet.2017.06.009	2017
	Antibacterial Activity of Isobavachalcone (IBC) Is Associated with Membrane Disruption.	Assis LR, Theodoro RDS, Costa MBS, Nascentes JAS, Rocha MDD, Bessa MAS, Menezes RP, Dilarri G, Hypolito GB, Santos VRD, Duque C, Ferreira H, Martins CHG, Regasini LO.	Membranes (Basel)	10.3390/membranes12030269	2022
	Antibacterial and Cytotoxic Activities of Pinus tropicalis and Pinus elliottii Resins and of the Diterpene Dehydroabietic Acid Against Bacteria That Cause Dental Caries.	da Silva KR, Damasceno JL, Inacio MO, Abrao F, Ferreira NH, Tavares DC, Ambrosio SR, Veneziani RCS, Martins CHG.	Front Microbiol	10.3389/fmicb.2019.00987	2019
	Assessment of Disinfection Potential of Q-Switch Nd: YAG Laser on Contaminated Titanium Implant Surfaces.	Namour M, Mobadder ME, Mulongo B, Fagnart O, Harb A, Peremans A, Verspecht T, Teughels W, Nammour S, Rompen E.	Materials (Basel)	10.3390/ma14206078	2021
Proteome	Determination of antibacterial activity and metabolite profile of Ruta graveolens against Streptococcus mutans and Streptococcus sobrinus.	Salman HA, Venkatesh S, Senthilkumar R, Gnanesh Kumar BS, Ali AM.	J Lab Physicians	10.4103/jlp.jlp_160_17	2018
	Hibiscus moscheutos L. Flower Petals Extract Phenolic Profile and In Vitro Antimicrobial, Biofilm Formation, Autoaggregation, Prebiotic, Genotoxicity, and Anti-Inflammatory Properties.	Kowalczyk P, Klewicka E, Milala J, Piekarska-Radzik L, Karlinska E, Sojka M, Klewicki R.	Molecules	10.3390/molecules30173569	2025
	Antimicrobial and anti-biofilm activities of Lactobacillus kefiranofaciens DD2 against oral pathogens.	Jeong D, Kim DH, Song KY, Seo KH.	J Oral Microbiol	10.1080/20002297.2018.1472985	2018
	The Proteome of Community Living Candida albicans Is Differentially Modulated by the Morphologic and Structural Features of the Bacterial Cohabitants.	Truong T, Pang LM, Rajan S, Wong SSW, Fung YME, Samaranayake L, Seneviratne CJ.	Microorganisms	10.3390/microorganisms8101541	2020
	Design, Synthesis and Biological Evaluation of Lophanic Acid Derivatives as Antifungal and Antibacterial Agents.	Yu X, Song X, Zhang Y, Yang Y, Ye J, Liu Y, Pan L, Zhang H.	Molecules	10.3390/molecules27206836	2022
Metabolism	In vitro Increased Respiratory Activity of Selected Oral Bacteria May Explain Competitive and Collaborative Interactions in the Oral Microbiome.	Hernandez-Sanabria E, Slomka V, Herrero ER, Kerckhof FM, Zaidel L, Teughels W, Boon N.	Front Cell Infect Microbiol	10.3389/fcimb.2017.00235	2017
Pathogenicity	10-undecynoic acid is a new anti-adherent agent killing biofilm of oral Streptococcus spp.	Goc A, Sumera W, Niedzwiecki A, Rath M.	PLoS One	10.1371/journal.pone.0214763	2019
	In Vitro Activity of Propolis on Oral Microorganisms and Biofilms.	Stahli A, Schroter H, Bullitta S, Serralutzu F, Dore A, Nietzsche S, Milia E, Sculean A, Eick S.	Antibiotics (Basel)	10.3390/antibiotics10091045	2021
	Fragmentation Study, Dual Anti-Bactericidal and Anti-Viral Effects and Molecular Docking of Cobalt(III) Complexes.	Fernandes LP, Silva JMB, Martins DOS, Santiago MB, Martins CHG, Jardim ACG, Oliveira GS, Pivatto M, Souza RAC, Franca EF, Deflon VM, Machado AEH, Oliveira CG.	Int J Mol Sci	10.3390/ijms21218355	2020
	Natural Antimicrobials and Oral Microorganisms: A Systematic Review on Herbal Interventions for the Eradication of Multispecies Oral Biofilms.	Karygianni L, Al-Ahmad A, Argyropoulou A, Hellwig E, Anderson AC, Skaltsounis AL.	Front Microbiol	10.3389/fmicb.2015.01529	2015
Enzymology	Streptococcus mutans isolated from a 4-year-old girl diagnosed with infective endocarditis.	Kondo Y, Hoshino T, Ogawa M, Hidaka K, Hasuwa T, Moriuchi H, Fujiwara T.	Clin Exp Dent Res	10.1002/cre2.220	2019
	Q-Switch Nd:YAG Laser-Assisted Elimination of Multi-Species Biofilm on Titanium Surfaces.	Namour M, Namour M, Verspecht T, El Mobadder M, Teughels W, Peremans A, Nammour S, Rompen E.	Materials (Basel)	10.3390/ma13071573	2020
	Antibacterial Effect of Copaifera duckei Dwyer Oleoresin and Its Main Diterpenes against Oral Pathogens and Their Cytotoxic Effect.	Abrao F, Alves JA, Andrade G, de Oliveira PF, Ambrosio SR, Veneziani RCS, Tavares DC, Bastos JK, Martins CHG.	Front Microbiol	10.3389/fmicb.2018.00201	2018
Pathogenicity	Deacidification of Cranberry Juice Reduces Its Antibacterial Properties against Oral Streptococci but Preserves Barrier Function and Attenuates the Inflammatory Response of Oral Epithelial Cells.	Pellerin G, Bazinet L, Grenier D.	Foods	10.3390/foods10071634	2021
	Anti-Planktonic and Anti-Biofilm Properties of Pentacyclic Triterpenes-Asiatic Acid and Ursolic Acid as Promising Antibacterial Future Pharmaceuticals.	Sycz Z, Tichaczek-Goska D, Wojnicz D.	Biomolecules	10.3390/biom12010098	2022
	Antimicrobial Activity, Biocompatibility and Anti-inflammatory Properties of Cetylpyridinium Chloride-based Mouthwash Containing Sodium Fluoride and Xylitol: An In Vitro Study.	LeBel G, Vaillancourt K, Morin MP, Grenier D.	Oral Health Prev Dent	10.3290/j.ohpd.b871071	2020
Pathogenicity	Oral biofilms exposure to chlorhexidine results in altered microbial composition and metabolic profile.	Chatzigiannidou I, Teughels W, Van de Wiele T, Boon N.	NPJ Biofilms Microbiomes	10.1038/s41522-020-0124-3	2020
Phylogeny	Oral Streptococci Biofilm Formation on Different Implant Surface Topographies.	Pita PP, Rodrigues JA, Ota-Tsuzuki C, Miato TF, Zenobio EG, Giro G, Figueiredo LC, Goncalves C, Gehrke SA, Cassoni A, Shibli JA.	Biomed Res Int	10.1155/2015/159625	2015
	Screening for antibacterial and antibiofilm activity in Thai medicinal plant extracts against oral microorganisms.	Teanpaisan R, Kawsud P, Pahumunto N, Puripattanavong J.	J Tradit Complement Med	10.1016/j.jtcme.2016.06.007	2017
Pathogenicity	The spherical nanoparticle-encapsulated chlorhexidine enhances anti-biofilm efficiency through an effective releasing mode and close microbial interactions.	Li X, Wong CH, Ng TW, Zhang CF, Leung KC, Jin L.	Int J Nanomedicine	10.2147/ijn.s105681	2016
	Rapid synthesis of bismuth-organic frameworks as selective antimicrobial materials against microbial biofilms.	Huang R, Zhou Z, Lan X, Tang FK, Cheng T, Sun H, Cham-Fai Leung K, Li X, Jin L.	Mater Today Bio	10.1016/j.mtbio.2022.100507	2023
	Antimicrobial Activity of the Essential Oil of Plectranthus neochilus against Cariogenic Bacteria.	Crevelin EJ, Caixeta SC, Dias HJ, Groppo M, Cunha WR, Martins CH, Crotti AE, Crotti AE.	Evid Based Complement Alternat Med	10.1155/2015/102317	2015
	Scardovia wiggsiae and its potential role as a caries pathogen.	Kressirer CA, Smith DJ, King WF, Dobeck JM, Starr JR, Tanner ACR.	J Oral Biosci	10.1016/j.job.2017.05.002	2017
Pathogenicity	The Comparative Evaluation of the Antimicrobial Effect of Propolis with Chlorhexidine against Oral Pathogens: An In Vitro Study.	Akca AE, Akca G, Topcu FT, Macit E, Pikdoken L, Ozgen IS.	Biomed Res Int	10.1155/2016/3627463	2016
Enzymology	Screening of Probiotic Candidates in Human Oral Bacteria for the Prevention of Dental Disease.	Terai T, Okumura T, Imai S, Nakao M, Yamaji K, Ito M, Nagata T, Kaneko K, Miyazaki K, Okada A, Nomura Y, Hanada N.	PLoS One	10.1371/journal.pone.0128657	2015
	Coaggregation between probiotic bacteria and caries-associated strains: an in vitro study.	Twetman L, Larsen U, Fiehn NE, Stecksen-Blicks C, Twetman S.	Acta Odontol Scand	10.1080/00016350902984237	2009
Metabolism	Oral Microbiota Display Profound Differential Metabolic Kinetics and Community Shifts upon Incubation with Sucrose, Trehalose, Kojibiose, and Xylitol.	Onyango SO, De Clercq N, Beerens K, Van Camp J, Desmet T, Van de Wiele T.	Appl Environ Microbiol	10.1128/aem.01170-20	2020
	Chemical Constituents and Evaluation of Antimicrobial and Cytotoxic Activities of Kielmeyera coriacea Mart. & Zucc. Essential Oils.	Martins Cde M, do Nascimento EA, de Morais SA, de Oliveira A, Chang R, Cunha LC, Martins MM, Martins CH, Moraes Tda S, Rodrigues PV, da Silva CV, de Aquino FJ.	Evid Based Complement Alternat Med	10.1155/2015/842047	2015
	Effect of Silver Diamine Fluoride and Potassium Iodide Treatment on Secondary Caries Prevention and Tooth Discolouration in Cervical Glass Ionomer Cement Restoration.	Zhao IS, Mei ML, Burrow MF, Lo EC, Chu CH.	Int J Mol Sci	10.3390/ijms18020340	2017
Pathogenicity	Nanoparticle-encapsulated chlorhexidine against oral bacterial biofilms.	Seneviratne CJ, Leung KC, Wong CH, Lee SF, Li X, Leung PC, Lau CB, Wat E, Jin L.	PLoS One	10.1371/journal.pone.0103234	2014
	Triclosan: A Small Molecule with Controversial Roles.	Sinicropi MS, Iacopetta D, Ceramella J, Catalano A, Mariconda A, Pellegrino M, Saturnino C, Longo P, Aquaro S.	Antibiotics (Basel)	10.3390/antibiotics11060735	2022
Pathogenicity	Antimicrobial activity of the essential oil of Tetradenia riparia (Hochst.) Codd. (Lamiaceae) against cariogenic bacteria.	de Melo NI, de Carvalho CE, Fracarolli L, Cunha WR, Veneziani RC, Martins CH, Crotti AE, Crotti AE.	Braz J Microbiol	10.1590/s1517-838246246220140649	2015
Metabolism	Differential Utilization of Basic Proline-Rich Glycoproteins during Growth of Oral Bacteria in Saliva.	Zhou Y, Yang J, Zhang L, Zhou X, Cisar JO, Palmer RJ.	Appl Environ Microbiol	10.1128/aem.01111-16	2016
Metabolism	Potential prebiotic substrates modulate composition, metabolism, virulence and inflammatory potential of an in vitro multi-species oral biofilm.	Verspecht T, Van Holm W, Boon N, Bernaerts K, Daep CA, Masters JG, Zayed N, Quirynen M, Teughels W.	J Oral Microbiol	10.1080/20002297.2021.1910462	2021
	[Influence of surface roughness on oral streptococcal adhesion forces to dental filling materials].	Sainan Z, Li J, Lei Z, Liying H, Lu Y, Wei L.	Hua Xi Kou Qiang Yi Xue Za Zhi	10.7518/hxkq.2016.05.003	2016
Pathogenicity	Antibacterial effects of silver diamine fluoride on multi-species cariogenic biofilm on caries.	Mei ML, Mei ML, Li QL, Chu CH, Lo EC, Samaranayake LP.	Ann Clin Microbiol Antimicrob	10.1186/1476-0711-12-4	2013
	Comparison of the modulatory effects of three structurally similar potential prebiotic substrates on an in vitro multi-species oral biofilm.	Verspecht T, Van Holm W, Boon N, Bernaerts K, Daep CA, Zayed N, Quirynen M, Teughels W.	Sci Rep	10.1038/s41598-021-94510-z	2021
	Antibacterial effect of a new haemostatic agent on oral microorganisms.	Cinar C, Odabas ME, Akca G, Isik B.	J Clin Exp Dent	10.4317/jced.50750	2012
	Effect of orthodontic bonding steps on the initial adhesion of mutans streptococci in the presence of saliva.	Yang IH, Lim BS, Park JR, Hyun JY, Ahn SJ.	Angle Orthod	10.2319/062210-343.1	2011
Metabolism	Polyphosphate-Accumulating Bacteria: Potential Contributors to Mineral Dissolution in the Oral Cavity.	Breiland AA, Flood BE, Nikrad J, Bakarich J, Husman M, Rhee T, Jones RS, Bailey JV.	Appl Environ Microbiol	10.1128/aem.02440-17	2018
	Functional ginger extracts from supercritical fluid carbon dioxide extraction via in vitro and in vivo assays: antioxidation, antimicroorganism, and mice xenografts models.	Lee CC, Chiou LY, Wang JY, Chou SY, Lan JC, Huang TS, Huang KC, Wang HM.	ScientificWorldJournal	10.1155/2013/210845	2013
	Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface.	Calatayud Arroyo M, Van de Wiele T, Hernandez-Sanabria E.	J Vis Exp	10.3791/57699	2018
	Purification and Anti-pathogenic Properties of Immunoglobulin Concentrates from Porcine Blood.	Jung TH, Choi JH, Koh KC, Jeon WM, Han KS.	Korean J Food Sci Anim Resour	10.5851/kosfa.2017.37.5.743	2017
	Determination of the antibacterial activity of crude extracts and compounds isolated from Hortia oreadica (Rutaceae) against oral pathogens.	Severino VG, da Silva MF, Lucarini R, Montanari LB, Cunha WR, Vinholis AH, Martins CH.	Braz J Microbiol	10.1590/s1517-838220090003000015	2009
	Seasonal variation of the chemical composition and antimicrobial and cytotoxic activities of the essential oils from Inga laurina (Sw.) Willd.	Furtado FB, de Aquino FJ, Nascimento EA, de M Martins C, de Morais SA, Chang R, Cunha LC, Leandro LF, Martins CH, Martins MM, da Silva CV, Machado FC, de Oliveira A.	Molecules	10.3390/molecules19044560	2014
	Piper betle (L): Recent Review of Antibacterial and Antifungal Properties, Safety Profiles, and Commercial Applications.	Nayaka NMDMW, Sasadara MMV, Sanjaya DA, Yuda PESK, Dewi NLKAA, Cahyaningsih E, Hartati R.	Molecules	10.3390/molecules26082321	2021
Enzymology	Comparison of the vaginal microbiota diversity of women with and without human papillomavirus infection: a cross-sectional study.	Gao W, Weng J, Gao Y, Chen X.	BMC Infect Dis	10.1186/1471-2334-13-271	2013
Enzymology	Development of species-specific primers for detection of Streptococcus mutans in mixed bacterial samples.	Chen Z, Saxena D, Caufield PW, Ge Y, Wang M, Li Y.	FEMS Microbiol Lett	10.1111/j.1574-6968.2007.00756.x	2007
	Application of bacteriocins in food preservation and infectious disease treatment for humans and livestock: a review.	Ng ZJ, Zarin MA, Lee CK, Tan JS.	RSC Adv	10.1039/d0ra06161a	2020
Phylogeny	Isolation and Bacteriocin-Related Typing of Streptococcus dentisani.	Conrads G, Westenberger J, Lurkens M, Abdelbary MMH.	Front Cell Infect Microbiol	10.3389/fcimb.2019.00110	2019
	In vivo biofilm formation on stainless steel bonded retainers during different oral health-care regimens.	Jongsma MA, van der Mei HC, Atema-Smit J, Busscher HJ, Ren Y.	Int J Oral Sci	10.1038/ijos.2014.69	2015
	Plant polyphenols and their anti-cariogenic properties: a review.	Ferrazzano GF, Amato I, Ingenito A, Zarrelli A, Pinto G, Pollio A.	Molecules	10.3390/molecules16021486	2011
	Nucleotide sequence analysis of the gtfT gene from Streptococcus sobrinus OMZ176.	Hanada N, Isobe Y, Aizawa Y, Katayama T, Sato S, Inoue M.	Infect Immun	10.1128/iai.61.5.2096-2103.1993	1993
Pathogenicity	Pimarane-type diterpenes: antimicrobial activity against oral pathogens.	Porto TS, Rangel R, Furtado NA, de Carvalho TC, Martins CH, Veneziani RC, Da Costa FB, Vinholis AH, Cunha WR, Heleno VC, Ambrosio SR.	Molecules	10.3390/molecules14010191	2009
	Anticariogenic properties of ent-pimarane diterpenes obtained by microbial transformation.	Severiano ME, Simao MR, Porto TS, Martins CH, Veneziani RC, Furtado NA, Arakawa NS, Said S, de Oliveira DC, Cunha WR, Gregorio LE, Ambrosio SR.	Molecules	10.3390/molecules15128553	2010
	Mutans streptococci genetic strains in children with severe early childhood caries: follow-up study at one-year post-dental rehabilitation therapy.	Palmer EA, Vo A, Hiles SB, Peirano P, Chaudhry S, Trevor A, Kasimi I, Pollard J, Kyles C, Leo M, Wilmot B, Engle J, Peterson J, Maier T, Machida CA.	J Oral Microbiol	10.3402/jom.v4i0.19530	2012
	Streptococcus salivarius fimbriae are composed of a glycoprotein containing a repeated motif assembled into a filamentous nondissociable structure.	Levesque C, Vadeboncoeur C, Chandad F, Frenette M.	J Bacteriol	10.1128/jb.183.9.2724-2732.2001	2001
Enzymology	Comparison of culture media and chairside assays for enumerating mutans streptococci.	Hildebrandt GH, Bretz WA.	J Appl Microbiol	10.1111/j.1365-2672.2006.02877.x	2006
Metabolism	Residue Leu940 has a crucial role in the linkage and reaction specificity of the glucansucrase GTF180 of the probiotic bacterium Lactobacillus reuteri 180.	Meng X, Dobruchowska JM, Pijning T, Lopez CA, Kamerling JP, Dijkhuizen L.	J Biol Chem	10.1074/jbc.m114.602524	2014
Enzymology	Identification of Streptococcus sobrinus with monoclonal antibodies.	de Soet JJ, van Dalen PJ, Appelmelk BJ, de Graaff J.	J Clin Microbiol	10.1128/jcm.25.12.2285-2288.1987	1987
Enzymology	Identification of Abiotrophia adiacens and Abiotrophia defectiva by 16S rRNA gene PCR and restriction fragment length polymorphism analysis.	Ohara-Nemoto Y, Tajika S, Sasaki M, Kaneko M.	J Clin Microbiol	10.1128/jcm.35.10.2458-2463.1997	1997
Pathogenicity	In vitro susceptibility of Streptococcus mutans to chlorhexidine and six other antimicrobial agents.	Jarvinen H, Tenovuo J, Huovinen P.	Antimicrob Agents Chemother	10.1128/aac.37.5.1158	1993
Pathogenicity	Systematic approach to optimizing specifically targeted antimicrobial peptides against Streptococcus mutans.	He J, Yarbrough DK, Kreth J, Anderson MH, Shi W, Eckert R.	Antimicrob Agents Chemother	10.1128/aac.01391-09	2010
Phylogeny	Description and evaluation of the semiautomated 4-hour rapid ID 32 Strep method for identification of streptococci and members of related genera.	Freney J, Bland S, Etienne J, Desmonceaux M, Boeufgras JM, Fleurette J.	J Clin Microbiol	10.1128/jcm.30.10.2657-2661.1992	1992
	Demonstration of human immunoglobulin G Fc-binding activity in oral bacteria.	Grenier D, Michaud J.	Clin Diagn Lab Immunol	10.1128/cdli.1.2.247-249.1994	1994
Enzymology	Distribution of proteins similar to IIIManH and IIIManL of the Streptococcus salivarius phosphoenolpyruvate:mannose-glucose phosphotransferase system among oral and nonoral bacteria.	Pelletier M, Frenette M, Vadeboncoeur C.	J Bacteriol	10.1128/jb.177.9.2270-2275.1995	1995
Phylogeny	Comparison of phenotypic characteristics, DNA-DNA hybridization results, and results with a commercial rapid biochemical and enzymatic reaction system for identification of viridans group streptococci.	Kikuchi K, Enari T, Totsuka K, Shimizu K.	J Clin Microbiol	10.1128/jcm.33.5.1215-1222.1995	1995
Enzymology	Real-time polymerase chain reaction quantification of the salivary levels of cariogenic bacteria in patients with orthodontic fixed appliances.	Al-Melh MA, Bhardwaj RG, Pauline EM, Karched M.	Clin Exp Dent Res	10.1002/cre2.285	2020
Pathogenicity	Evaluation of the cariogenic potential of a probiotic candidate strain Lactobacillus gasseri YIT 12321.	Okada A, Imai S, Kikuchi T, Matin K, Otsuka R, Terai T, Okumura T, Yamamoto T, Hanada N	Arch Oral Biol	10.1016/j.archoralbio.2022.105364	2022
Pathogenicity	Optical coherence tomography and polarized light microscopy for the evaluation of artificial caries: a preliminary study.	Quitero MFZ, Siriani LK, Azevedo CS, Freitas AZ, Scaramucci T, Simionato MRL, Matos AB	Gen Dent		2019
	Inhibition of Streptococcus mutans and S. sobrinus biofilms by liamocins from Aureobasidium pullulans.	Leathers TD, Rich JO, Bischoff KM, Skory CD, Nunnally MS	Biotechnol Rep (Amst)	10.1016/j.btre.2018.e00300	2018
Pathogenicity	Antimicrobial and biological activity of leachate from light curable pulp capping materials.	Arias-Moliz MT, Farrugia C, Lung CYK, Wismayer PS, Camilleri J	J Dent	10.1016/j.jdent.2017.06.006	2017
Pathogenicity	Sol-gel-derived bioactive glasses demonstrate antimicrobial effects on common oral bacteria.	Salehi S, Davis HB, Ferracane JL, Mitchell JC	Am J Dent		2015
	Synergistic effect of xylitol and ursolic acid combination on oral biofilms.	Zou Y, Lee Y, Huh J, Park JW	Restor Dent Endod	10.5395/rde.2014.39.4.288	2014
Pathogenicity	Systematic screening of plant extracts from the Brazilian Pantanal with antimicrobial activity against bacteria with cariogenic relevance.	Brighenti FL, Salvador MJ, Delbem AC, Delbem AC, Oliveira MA, Soares CP, Freitas LS, Koga-Ito CY	Caries Res	10.1159/000357225	2014
Metabolism	Streptococcus mutans and Streptococcus sobrinus biofilm formation and metabolic activity on dental materials.	Hahnel S, Muhlbauer G, Hoffmann J, Ionescu A, Burgers R, Rosentritt M, Handel G, Haberlein I	Acta Odontol Scand	10.3109/00016357.2011.600703	2011
Pathogenicity	Antimicrobial effect of Korean propolis against the mutans streptococci isolated from Korean.	Kim MJ, Kim CS, Kim BH, Ro SB, Lim YK, Park SN, Cho E, Ko JH, Kwon SS, Ko YM, Kook JK	J Microbiol	10.1007/s12275-011-1002-8	2011
Pathogenicity	Inhibition by hop bract polyphenols of cellular adherence and water-insoluble glucan synthesis of mutans streptococci.	Tagashira M, Uchiyama K, Yoshimura T, Shirota M, Uemitsu N	Biosci Biotechnol Biochem	10.1271/bbb.61.332	1997
Genetics	Complete Genome Sequences of Streptococcus sobrinus SL1 (ATCC 33478 = DSM 20742), NIDR 6715-7 (ATCC 27351), NIDR 6715-15 (ATCC 27352), and NCTC 10919 (ATCC 33402).	Sales MJ, Herbert WG, Du Y, Sandur AS, Stanley NM, Jensen PA	Microbiol Resour Announc	10.1128/MRA.00804-18	2018
Pathogenicity	Effect of antiplaque compounds and mouthrinses on the activity of glucosyltransferases from Streptococcus sobrinus and insoluble glucan production.	Furiga A, Dols-Lafargue M, Heyraud A, Chambat G, Lonvaud-Funel A, Badet C	Oral Microbiol Immunol	10.1111/j.1399-302X.2008.00441.x	2008
Pathogenicity	Effects of low-concentrated chlorhexidine on growth of Streptococcus sobrinus and primary human gingival fibroblasts.	Dogan S, Gunay H, Leyhausen G, Geurtsen W	Clin Oral Investig	10.1007/s00784-003-0226-3	2003
Pathogenicity	Effects of topical application of free and liposome-encapsulated lactoferrin and lactoperoxidase on oral microbiota and dental caries in rats.	Martinez-Gomis J, Fernandez-Solanas A, Vinas M, Gonzalez P, Planas ME, Sanchez S	Arch Oral Biol	10.1016/s0003-9969(99)00092-8	1999
	[Fluorescence spectroscopy shows porphyrins produced by cultured oral bacteria differ depending on composition of growth media.].	Lennon AM, Brune L, Techert S, Buchalla W	Caries Res	10.1159/000528731	2022
Phylogeny	Streptococcusdentiloxodontae sp. nov., isolated from the oral cavity of elephants.	Shinozaki-Kuwahara N, Saito M, Hirasawa M, Hirasawa M, Takada K	Int J Syst Evol Microbiol	10.1099/ijsem.0.001280	2016

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#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#39849	; Curators of the CIP;
#48255	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 25735
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#68371	Automatically annotated from API 50CH acid .
#68381	Automatically annotated from API rID32STR .
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#122647	Collection of Institut Pasteur ; Curators of the CIP; CIP 103230
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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About us

Streptococcus sobrinus (DSM 20742, ATCC 33478, CCM 6070)

Name and taxonomic classification

Morphology

Cell morphology

Colony morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Murein

Metabolite utilization

Metabolite production

Metabolite tests

Enzymes

Fatty acid profile

API zym

API 50CHac

API rID32STR

Isolation, sampling and environmental information

Isolation source categories

Isolation

Taxonmaps

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_003172995

16S sequences

GC content

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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