Streptococcus anginosus subsp. anginosus (DSM 20563, ATCC 12395, ATCC 33397)

Name: Streptococcus anginosus subsp. anginosus (DSM 20563, ATCC 12395, ATCC 33397)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 14717

Type strain

Strain Designation Havill III. (R. Lancefield F68A), Havill III, F68A

Culture col. no. DSM 20563 ATCC 12395 ATCC 33397 NCTC 10713 CCUG 27298 10 more

NCBI tax ID(s) 1328 1671923

Special Collections DSMZ CCUG JCM CIP

History <- NCTC; NCTC 10713 <- R. Colman and R. Lancefield; F68A <- E.A. Bliss, St. Marys Hospital London, UK; Havill III CCUG 27298 <-- NCFB 2496 <-- NCTC 10713 <-- G. Colman <-- R. C. Lancefield F68A <-- E. A. Bliss strain Havill lll. CIP <- 1987, NCTC, Streptococcus sp. <- 1970 G. Colman <- R. Lancefield <- E.A. Bliss

Links

Streptococcus anginosus subsp. anginosus Havill III. is a microaerophile, Gram-positive, coccus-shaped human pathogen that was isolated from human throat.

Gram-positive coccus-shaped microaerophile human pathogen genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 92727

LMG 14502,ATCC 33397,CCUG 27298,NCFB 2496,NCTC 10713,ATCC 12395,CCUG 35776,CIP 102921,NCDO 2496,NCIMB 702496,CECT 948,HAMBI 1525,BCRC 14730,CCRC 14730,JCM 12993,KCTC 3983,CNCTC 6655,DSM 20563

@ref 20215

Last LPSN update 2026-02-09 11:21:29

Domain Bacteria

Phylum Bacillota

Class Bacilli

Order Lactobacillales

Family Streptococcaceae

Genus Streptococcus

Species Streptococcus anginosus subsp. anginosus

Full scientific name Streptococcus anginosus subsp. anginosus (Andrewes and Horder 1906) Jensen et al. 2013

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Confidence
116383	positive	coccus-shaped
125438			92
125439	positive		95.8

Colony morphology

@ref	Type of hemolysis	Hemolysis ability
8913	beta	1
116383		1

Multimedia

@ref:	66793
multimedia content:	EM_DSM_20563_1.jpg
multimedia.multimedia content:	EM_DSM_20563_1.jpg
caption:	electron microscopic image
intellectual property rights:	© HZI/Manfred Rohde
manual_annotation:	1

@ref:	66793
multimedia content:	EM_DSM_20563_2.jpg
multimedia.multimedia content:	EM_DSM_20563_2.jpg
caption:	electron microscopic image
intellectual property rights:	© HZI/Manfred Rohde
manual_annotation:	1

@ref:	66793
multimedia content:	EM_DSM_20563_3.jpg
multimedia.multimedia content:	EM_DSM_20563_3.jpg
caption:	electron microscopic image
intellectual property rights:	© HZI/Manfred Rohde
manual_annotation:	1

@ref:	66793
multimedia content:	EM_DSM_20563_4.jpg
multimedia.multimedia content:	EM_DSM_20563_4.jpg
caption:	electron microscopic image
intellectual property rights:	© HZI/Manfred Rohde
manual_annotation:	1

@ref:	66793
multimedia content:	EM_DSM_20563_5.jpg
multimedia.multimedia content:	EM_DSM_20563_5.jpg
caption:	electron microscopic image
intellectual property rights:	© HZI/Manfred Rohde
manual_annotation:	1

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
8913	COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)	Medium recipe at MediaDive	Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
8913	TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)	Medium recipe at MediaDive	Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water
41326	MEDIUM 3 - Columbia agar		Columbia agar (39.000 g);distilled water (1000.000 ml)
116383	CIP Medium 72	Medium recipe at CIP
116383	CIP Medium 3	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
8913	positive	growth	37
41326	positive	growth	37
67770	positive	growth	37
116383	positive	growth	30-45
116383	negative	growth	10

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
8913	microaerophile
116383	facultative anaerobe
125439	microaerophile	98.7

Spore formation

@ref	Spore formation	Confidence
125439		92.9

Halophily

@ref	Salt	Growth	Tested relation	Concentration
116383	NaCl		growth	6.5 %

Murein

@ref	Murein short key	Type
8913	A11.05	A3alpha L-Lys-L-Ala₂

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68381	40585 ChEBI	alpha-cyclodextrin	-	builds acid from	from API rID32STR
68371	27613 ChEBI	amygdalin	+	builds acid from	from API 50CH acid
68371	18305 ChEBI	arbutin	+	builds acid from	from API 50CH acid
68381	29016 ChEBI	arginine	+	hydrolysis	from API rID32STR
68371	17057 ChEBI	cellobiose	+	builds acid from	from API 50CH acid
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68381	18333 ChEBI	D-arabitol	-	builds acid from	from API rID32STR
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68371	15824 ChEBI	D-fructose	+	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	+	builds acid from	from API 50CH acid
68371	17634 ChEBI	D-glucose	+	builds acid from	from API 50CH acid
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68381	16899 ChEBI	D-mannitol	-	builds acid from	from API rID32STR
68371	16899 ChEBI	D-mannitol	-	builds acid from	from API 50CH acid
68371	16024 ChEBI	D-mannose	+	builds acid from	from API 50CH acid
68381	16988 ChEBI	D-ribose	-	builds acid from	from API rID32STR
68371	16988 ChEBI	D-ribose	-	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68371	16443 ChEBI	D-tagatose	-	builds acid from	from API 50CH acid
68381	16443 ChEBI	D-tagatose	-	builds acid from	from API rID32STR
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
116383	4853 ChEBI	esculin	+	hydrolysis
68371	4853 ChEBI	esculin	+	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68371	28066 ChEBI	gentiobiose	+	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	-	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
68381	28087 ChEBI	glycogen	-	builds acid from	from API rID32STR
68371	28087 ChEBI	glycogen	+	builds acid from	from API 50CH acid
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68381	30849 ChEBI	L-arabinose	-	builds acid from	from API rID32STR
68371	30849 ChEBI	L-arabinose	-	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68371	17716 ChEBI	lactose	+	builds acid from	from API 50CH acid
68381	17306 ChEBI	maltose	+	builds acid from	from API rID32STR
68371	17306 ChEBI	maltose	+	builds acid from	from API 50CH acid
68371	6731 ChEBI	melezitose	-	builds acid from	from API 50CH acid
68381	6731 ChEBI	melezitose	-	builds acid from	from API rID32STR
68371	28053 ChEBI	melibiose	+	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68381	320055 ChEBI	methyl beta-D-glucopyranoside	+	builds acid from	from API rID32STR
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
68371	59640 ChEBI	N-acetylglucosamine	+	builds acid from	from API 50CH acid
116383	17632 ChEBI	nitrate	-	reduction
116383	16301 ChEBI	nitrite	-	reduction
68371		Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371		Potassium 5-ketogluconate	-	builds acid from	from API 50CH acid
68381	27941 ChEBI	pullulan	+	builds acid from	from API rID32STR
68371	16634 ChEBI	raffinose	+	builds acid from	from API 50CH acid
68381	16634 ChEBI	raffinose	+	builds acid from	from API rID32STR
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
68371	17814 ChEBI	salicin	+	builds acid from	from API 50CH acid
68381	30911 ChEBI	sorbitol	-	builds acid from	from API rID32STR
68371	28017 ChEBI	starch	+	builds acid from	from API 50CH acid
68381	17992 ChEBI	sucrose	+	builds acid from	from API rID32STR
68371	17992 ChEBI	sucrose	+	builds acid from	from API 50CH acid
68381	27082 ChEBI	trehalose	+	builds acid from	from API rID32STR
68371	27082 ChEBI	trehalose	+	builds acid from	from API 50CH acid
68371	32528 ChEBI	turanose	+	builds acid from	from API 50CH acid
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68381	15688 ChEBI	acetoin		from API rID32STR

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test
68381	15688 ChEBI	acetoin	+	from API rID32STR

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
68381	Alanyl-Phenylalanyl-Proline arylamidase	+		from API rID32STR
116383	alcohol dehydrogenase	+	1.1.1.1
68381	alkaline phosphatase	+	3.1.3.1	from API rID32STR
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	+	3.2.1.22	from API zym
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68381	arginine dihydrolase	+	3.5.3.6	from API rID32STR
68381	beta-galactosidase	-	3.2.1.23	from API rID32STR
68382	beta-galactosidase	-	3.2.1.23	from API zym
116383	beta-galactosidase	-	3.2.1.23
68381	beta-glucosidase	+	3.2.1.21	from API rID32STR
68382	beta-glucosidase	+	3.2.1.21	from API zym
68381	beta-glucuronidase	-	3.2.1.31	from API rID32STR
68382	beta-glucuronidase	-	3.2.1.31	from API zym
8913	catalase	-	1.11.1.6
116383	catalase	-	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
8913	cytochrome-c oxidase	-	1.9.3.1
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	-		from API zym
68381	glycyl tryptophan arylamidase	-		from API rID32STR
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
116383	lysine decarboxylase	-	4.1.1.18
68381	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API rID32STR
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	-		from API zym
116383	ornithine decarboxylase	-	4.1.1.17
68381	pyrrolidonyl arylamidase	-	3.4.19.3	from API rID32STR
68382	trypsin	-	3.4.21.4	from API zym
68382	valine arylamidase	-		from API zym

Fatty acid profile

Metadata FA analysis

@ref

48705

Fatty acid	Percentage	ECL
C16:0	23.7	16
C18:1 ω7c /12t/9t	22.3	17.824
C14:0	14.5	14
C16:1 ω9c	9.8	15.774
C18:2 ω6,9c/C18:0 ANTE	7.9	17.724
C16:1 ω7c	7.6	15.819
C18:1 ω9c	7.3	17.769
C16:1 ω5c	3.7	15.908
C18:0	3.2	18

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
116383	-	+	+	-	-	+	-	-	-	-	+	-	+	-	-	+	+	-	-	-

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
116383	not determinedn.d.	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	-	-	-	-	+	+	+	+	+	+	+	+	+	+	+	-	-	+	+	+	-	+	+	-	-	-	-	-	-	-	-	-

API rID32STR

@ref	ADH (Arg)	beta GLU	beta GAR	beta GUR	alpha GAL	PAL	RIB	MAN	SOR	LAC	TRE	RAF	SAC	LARA	DARL	Acid from alpha-cyclodextrinCDEX	Acetoin production (Voges Proskauer test)VP	Alanyl-Phenylalanyl-Proline arylamidaseAPPA	beta GAL	Pyrrolidonyl arylamidasePyrA	N-Acetyl-glucosaminidasebeta NAG	Glycyl-tryptophan arylamidaseGTA	HIP	GLYG	PUL	MAL	MEL	MLZ	Acidification of methyl beta-D-glucopyranosideMbeta DG	TAG	beta MAN	URE
8913	+	+	-	-	-	+	-	-	-	+	+	+	+	-	-	-	+	+	-	-	-	-	-	-	+	+	-	-	+	-	+/-	-
8913	+	+	-	-	+/-	+	-	-	-	+	+	+	+	-	-	-	+	+	-	-	-	-	-	-	+	+	-	-	+	-	+/-	+
8913	+	+	-	-	+	+	-	-	-	+/-	+	+	+	-	-	-	+	+	-	-	-	-	-	-	+	+	-	-	+	-	+	-
8913	+	+	-	-	+/-	+	-	-	-	-	+	+	+	-	-	-	+	+	-	-	-	-	-	-	+	+	+/-	-	+	-	-	-
8913	+	+	-	-	+	+	-	-	-	+	+	+	+	-	-	-	+	+	-	-	-	-	+	-	+	+	-	-	+	-	+	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Host	#Human	-
#Host Body-Site	#Oral cavity and airways	#Throat

Isolation

@ref	Sample type
8913	human throat
67770	Tissue, human (human throat)

Taxonmaps

69479

Global distribution of 16S sequence LC258132 (>99% sequence identity) for Streptococcus from Microbeatlas

Aquatic Samples	2504
Soil Samples	1377
Animal Samples	107283
Plant Samples	731
Total Samples	111895

Interaction and safety

Risk assessment

@ref	Pathogenicity human	Pathogenicity animal	Biosafety level	Biosafety level comment
8913			2	Risk group (German classification) According to TRBA 466
116383			2	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	42197_F01 assembly for Streptococcus anginosus NCTC10713	complete	GCA_900636475	1328.82	8116414862	1328	99.51
124043	ASM2073576v1 assembly for Streptococcus anginosus subsp. anginosus FDAARGOS_1569	complete	GCA_020735765	1671923.4		1671923	90.85
66792	Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569	complete		1671923.5		1671923	85.17
66792	ASM208802v1 assembly for Streptococcus anginosus SK52 = DSM 20563 ATCC 33397	contig	GCA_002088025	1000570.31		1000570	76.69
66792	Streptococcus anginosus strain SK52 = DSM 20563	contig		1328.337		1328	76.6
66792	ASM1993010v1 assembly for Streptococcus anginosus SK52 = DSM 20563	contig	GCA_019930105	1328.317	8111291798	1328	76.25
66792	ASM37360v1 assembly for Streptococcus anginosus SK52 = DSM 20563	scaffold	GCA_000373605	1000570.8	2515154090	1000570	75.78
66792	ASM47405v1 assembly for Streptococcus anginosus SK52 = DSM 20563	contig	GCA_000474055	1000570.9	2602041681	1000570	73.26
66792	ASM21455v1 assembly for Streptococcus anginosus SK52 = DSM 20563	contig	GCA_000214555	1000570.3	651324100	1000570	55.27

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Streptococcus anginosus SK52 = DSM 20563 16S ribosomal RNA gene, partial sequence	JN787169	1404	1000570
20218	Streptococcus anginosus ATCC 12395 16S rRNA gene, partial sequence	U02909	396	1000570
8913	Streptococcus anginosus strain ATCC33397 16S ribosomal RNA gene, partial sequence	AF104678	1573	1000570
67770	Streptococcus anginosus gene for 16S ribosomal RNA, partial sequence, strain: JCM 12993	LC258132	1449	1328
67770	S.anginosus 16S rRNA	X58309	1334	1328
124043	Streptococcus anginosus gene for 16S ribosomal RNA, partial sequence, strain: ATCC 33397.	AB355609	1399	1000570
124043	Streptococcus anginosus strain ATCC 33397 16S ribosomal RNA gene, partial sequence.	GU045404	1477	1000570
124043	Streptococcus anginosus strain ATCC 33397 16S ribosomal RNA gene, partial sequence; 16S-23S ribosomal RNA intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence.	HM241932	602	1000570
124043	S.anginosus 16S ribosomal RNA.	Z69038	512	1328
124043	Streptococcus anginosus strain ATCC 33397 16S-23S ribosomal RNA intergenic spacer, complete sequence.	AY347541	391	1328
124043	Streptococcus anginosus culture-collection ATCC:33397 16S ribosomal RNA gene, partial sequence.	JN578465	1478	1328

GC content

@ref	GC-content (mol%)
8913	36.6
67770	38-40

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Streptococcus anginosus NCTC10713
NCBI: GCA_900636475

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	microaerophile	98.70	no
125439	gram_stain	BacteriaNetⓘ	positive	95.80	no
125439	motility	BacteriaNetⓘ	no	85.50	no
125439	spore_formation	BacteriaNetⓘ	no	92.90	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Streptococcus anginosus NCTC10713
NCBI: GCA_900636475.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	88.03	no
125438	anaerobic	anaerobicⓘ	no	91.80	no
125438	aerobic	aerobicⓘ	no	96.75	yes
125438	spore-forming	spore-formingⓘ	no	85.08	no
125438	thermophilic	thermophileⓘ	no	95.43	yes
125438	flagellated	motile2+ⓘ	no	92.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	A multiplex Taqman PCR assay for MRSA detection from whole blood.	Duraiswamy S, Agarwalla S, Lok KS, Tse YY, Wu R, Wang Z.	PLoS One	10.1371/journal.pone.0294782	2023
	Activity of five antimicrobial peptides against periodontal as well as non-periodontal pathogenic strains.	Enigk K, Jentsch H, Rodloff AC, Eschrich K, Stingu CS.	J Oral Microbiol	10.1080/20002297.2020.1829405	2020
	Colorectal Cancer Patients Have Four Specific Bacterial Species in Oral and Gut Microbiota in Common-A Metagenomic Comparison with Healthy Subjects.	Uchino Y, Goto Y, Konishi Y, Tanabe K, Toda H, Wada M, Kita Y, Beppu M, Mori S, Hijioka H, Otsuka T, Natsugoe S, Hara E, Sugiura T.	Cancers (Basel)	10.3390/cancers13133332	2021
	The Toothbrush Microbiome: Impact of User Age, Period of Use and Bristle Material on the Microbial Communities of Toothbrushes.	Zinn MK, Schages L, Bockmuhl D.	Microorganisms	10.3390/microorganisms8091379	2020
	Comparative genomics analysis of Streptococcus agalactiae reveals that isolates from cultured tilapia in China are closely related to the human strain A909.	Liu G, Zhang W, Lu C.	BMC Genomics	10.1186/1471-2164-14-775	2013
Genetics	Microevolution of Streptococcus agalactiae ST-261 from Australia Indicates Dissemination via Imported Tilapia and Ongoing Adaptation to Marine Hosts or Environment.	Kawasaki M, Delamare-Deboutteville J, Bowater RO, Walker MJ, Beatson S, Ben Zakour NL, Barnes AC.	Appl Environ Microbiol	10.1128/aem.00859-18	2018
	Identification of Streptococcus pneumoniae by a real-time PCR assay targeting SP2020.	Tavares DA, Handem S, Carvalho RJ, Paulo AC, de Lencastre H, Hinds J, Sa-Leao R.	Sci Rep	10.1038/s41598-019-39791-1	2019
	Evaluation of microbiota associated with Herpesviruses in active sites of generalized aggressive periodontitis.	Passariello C, Gigola P, Testarelli L, Puttini M, Schippa S, Petti S.	Ann Stomatol (Roma)	10.11138/ads/2017.8.2.071	2017
Phylogeny	Description and evaluation of the semiautomated 4-hour rapid ID 32 Strep method for identification of streptococci and members of related genera.	Freney J, Bland S, Etienne J, Desmonceaux M, Boeufgras JM, Fleurette J.	J Clin Microbiol	10.1128/jcm.30.10.2657-2661.1992	1992
Enzymology	Evaluation of a novel real-time PCR test based on the ssrA gene for the identification of group B streptococci in vaginal swabs.	Wernecke M, Mullen C, Sharma V, Morrison J, Barry T, Maher M, Smith T.	BMC Infect Dis	10.1186/1471-2334-9-148	2009
Enzymology	Construction of a DNA probe for the specific identification of Streptococcus oralis.	Schmidhuber S, Ludwig W, Schleifer KH.	J Clin Microbiol	10.1128/jcm.26.5.1042-1044.1988	1988
	Virulence factors of Streptococcus anginosus - a molecular perspective.	Kurylek A, Stasiak M, Kern-Zdanowicz I.	Front Microbiol	10.3389/fmicb.2022.1025136	2022
Genetics	Integrative analysis of gene and protein expression in atherosclerosis-related pathways modulated by periodontal pathogens. Systematic review.	Marroquin TY, Guauque-Olarte S.	Jpn Dent Sci Rev	10.1016/j.jdsr.2022.12.001	2023
	Estimation of bacterial hydrogen sulfide production in vitro.	Basic A, Blomqvist S, Carlen A, Dahlen G.	J Oral Microbiol	10.3402/jom.v7.28166	2015
	Accurate Differentiation of Streptococcus pneumoniae from other Species within the Streptococcus mitis Group by Peak Analysis Using MALDI-TOF MS.	Marin M, Cercenado E, Sanchez-Carrillo C, Ruiz A, Gomez Gonzalez A, Rodriguez-Sanchez B, Bouza E.	Front Microbiol	10.3389/fmicb.2017.00698	2017
Enzymology	Rapid identification of clinically relevant Enterococcus species by fluorescence in situ hybridization.	Wellinghausen N, Bartel M, Essig A, Poppert S.	J Clin Microbiol	10.1128/jcm.00861-07	2007
Metabolism	High-level fluorescence labeling of gram-positive pathogens.	Aymanns S, Mauerer S, van Zandbergen G, Wolz C, Spellerberg B.	PLoS One	10.1371/journal.pone.0019822	2011
Enzymology	Rapid and reliable identification of Streptococcus pneumoniae isolates by pneumolysin-mediated agglutination.	Cima-Cabal MD, Vazquez F, de los Toyos JR, Mendez FJ.	J Clin Microbiol	10.1128/jcm.37.6.1964-1966.1999	1999
Phylogeny	Evaluation of a rapid direct assay for identification of bacteria and the mec A and van genes from positive-testing blood cultures.	Eigner U, Weizenegger M, Fahr AM, Witte W.	J Clin Microbiol	10.1128/jcm.43.10.5256-5262.2005	2005
Phylogeny	Phenotypic differentiation of Streptococcus intermedius, Streptococcus constellatus, and Streptococcus anginosus strains within the "Streptococcus milleri group".	Whiley RA, Fraser H, Hardie JM, Beighton D.	J Clin Microbiol	10.1128/jcm.28.7.1497-1501.1990	1990
Metabolism	Sugar metabolism, an additional virulence factor in enterobacteria.	Le Bouguenec C, Schouler C.	Int J Med Microbiol	10.1016/j.ijmm.2010.04.021	2011
Metabolism	The stress of carrying CRISPR-Cas.	Haider D, Bauer R, Grempels A, Roscher R, Aslan CC, Mauerer S, Spellerberg B.	Virulence	10.1080/21505594.2025.2541701	2025
Transcriptome	Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations.	Lu Y, Xu L, Chen W, Liu W, Zhang Y, Zhou Q, Wang N, Zhang Y, Bai H, Xu S, Huang P, Fu K, Xie W, Liu X, Wang X, Wong CC, Kuang M, Yu J.	Cancer Discov	10.1158/2159-8290.cd-24-1259	2025
Transcriptome	Co-culturing with Streptococcus anginosus alters Staphylococcus aureus transcriptome when exposed to tonsillar cells.	Bastakoti S, Pesonen M, Ajayi C, Julin K, Corander J, Johannessen M, Hanssen AM.	Front Cell Infect Microbiol	10.3389/fcimb.2024.1326730	2024
	Synthesis of Rh-MOF/PVA-PVP nanofibers for skin cancer and infection inhibition.	Altharawi A, Aldakhil T, A Alossaimi M.	Front Chem	10.3389/fchem.2025.1575183	2025
	The Role of SilX in Bacteriocin Production of Streptococcus anginosus.	Vogel V, Fuchs M, Jachmann M, Bitzer A, Mauerer S, Munch J, Spellerberg B.	Front Microbiol	10.3389/fmicb.2022.904318	2022
Pathogenicity	Viridans Streptococcal Biofilm Evades Immune Detection and Contributes to Inflammation and Rupture of Atherosclerotic Plaques.	Karhunen PJ, Pessi T, Horkko S, Karhunen V, Goebeler S, Louhelainen AM, Martiskainen M, Haapaniemi T, Lappetelainen J, Ijas T, Lyytikainen LP, Raitoharju E, Sioris T, Tuomisto S, Huhtala H, Wang C, Monaco C, Oksala N, Lehtimaki T, Laaksonen R.	J Am Heart Assoc	10.1161/jaha.125.041521	2025
Pathogenicity	Oral streptococci S. anginosus and S. mitis induce distinct morphological, inflammatory, and metabolic signatures in macrophages.	Senthil Kumar S, Gunda V, Reinartz DM, Pond KW, Thorne CA, Santiago Raj PV, Johnson MDL, Wilson JE.	Infect Immun	10.1128/iai.00536-23	2024
	Antimicrobial Activity of Methylene Blue Associated with Photodynamic Therapy: In Vitro Study in Multi-Species Oral Biofilm.	Bueno-Silva B, Parma-Garcia J, Frigo L, Suarez LJ, Macedo TT, Uyeda FH, Melo MARDC, Sacco R, Mourao CF, Feres M, Shibli JA, Figueiredo LC.	Pathogens	10.3390/pathogens13040342	2024
	Tumor-associated bacteria activate PRDX1-driven glycolysis to promote immune evasion and PD-1 antibody resistance in hepatocellular carcinoma.	Zhang H, Lan X, Cai L, Gao X, Gao F, Yu D, Zhang J, Zhang J, Tai Q.	Front Microbiol	10.3389/fmicb.2025.1599691	2025
	Evaluation of the Microbial Profile on the Polydioxanone Membrane and the Collagen Membrane Exposed to Multi-Species Subgingival Biofilm: An In Vitro Study.	Cintra Moreira MV, Figueiredo LC, da Cunha Melo MAR, Uyeda FH, da Silva LDA, Macedo TT, Sacco R, Mourao CF, Shibli JA, Bueno-Silva B.	Membranes (Basel)	10.3390/membranes13120907	2023
	Multimodal inhibitory effect of matcha on Porphyromonas gingivalis.	Nakao R, Takatsuka A, Mandokoro K, Narisawa N, Ikeda T, Takai H, Ogata Y.	Microbiol Spectr	10.1128/spectrum.03426-23	2024
Pathogenicity	Antibacterial Activity of a Bioactive Tooth-Coating Material Containing Surface Pre-Reacted Glass in a Complex Multispecies Subgingival Biofilm.	Tanaka CJ, Rodrigues JA, Pingueiro JMS, Macedo TT, Feres M, Shibli JA, Bueno-Silva B.	Pharmaceutics	10.3390/pharmaceutics15061727	2023
	Mechanistic insights into endometriosis: roles of Streptococcus agalactiae and L-carnitine in lesion development and angiogenesis.	Zhuang Y, Lyu T, Chen Y, Li W, Tang L, Xian SP, Yang PF, Wang L, Zhang QQ, Mei C, Lin YJ, Yan Z, Li Z, He JZ, Zeng FM.	Angiogenesis	10.1007/s10456-025-09991-7	2025
Pathogenicity	Identification of highly potent competence stimulating peptide-based quorum sensing activators in Streptococcus mutans through the utilization of N-methyl and reverse alanine scanning.	Bikash CR, Tal-Gan Y.	Bioorg Med Chem Lett	10.1016/j.bmcl.2019.01.029	2019
Genetics	Comparative Genome Analysis of the Daptomycin-Resistant Streptococcus anginosus Strain J4206 Associated with Breakthrough Bacteremia.	Rahman M, Nguyen SV, McCullor KA, King CJ, Jorgensen JH, McShan WM.	Genome Biol Evol	10.1093/gbe/evw241	2016
Metabolism	Identification of Streptococcus gallolyticus subsp. gallolyticus (Biotype I) Competence-Stimulating Peptide Pheromone.	Harrington A, Tal-Gan Y.	J Bacteriol	10.1128/jb.00709-17	2018
	Nasal Rinsing with Probiotics-Microbiome Evaluation in Patients with Inflammatory Diseases of the Nasal Mucosa.	Brozek-Madry E, Ziuzia-Januszewska L, Misztal O, Burska Z, Sosnowska-Turek E, Sierdzinski J.	J Clin Med	10.3390/jcm14103341	2025
	Lactobacillus acidophilus impairs the establishment of pathogens in a subgingival multispecies biofilm.	Bueno MR, Dudu-Silva G, Macedo TT, Gomes APAP, Rodrigues Oliveira Braga A, Aguiar Silva LD, Bueno-Silva B.	Front Dent Med	10.3389/fdmed.2023.1212773	2023
Metabolism	Streptococcus gordonii pheromone s.g.cAM373 may influence the reservoir of antibiotic resistance determinants of Enterococcus faecalis origin in the oral metagenome.	Mansfield JM, Herrmann P, Jesionowski AM, Vickerman MM.	J Med Microbiol	10.1099/jmm.0.000613	2017
	Brazilian Red Propolis Is as Effective as Amoxicillin in Controlling Red-Complex of Multispecies Subgingival Mature Biofilm In Vitro.	de Figueiredo KA, da Silva HDP, Miranda SLF, Goncalves FJDS, de Sousa AP, de Figueiredo LC, Feres M, Bueno-Silva B.	Antibiotics (Basel)	10.3390/antibiotics9080432	2020
Enzymology	Streptococcus mutans isolated from a 4-year-old girl diagnosed with infective endocarditis.	Kondo Y, Hoshino T, Ogawa M, Hidaka K, Hasuwa T, Moriuchi H, Fujiwara T.	Clin Exp Dent Res	10.1002/cre2.220	2019
	Affordable blood culture systems from China: in vitro evaluation for use in resource-limited settings.	Hardy L, Vermoesen T, Genbrugge E, Natale A, Franquesa C, Gleeson B, Ferreyra C, Dailey P, Jacobs J.	EBioMedicine	10.1016/j.ebiom.2024.105004	2024
	Propolis, Aloe Vera, Green Tea, Cranberry, Calendula, Myrrha and Salvia Properties against Periodontal Microorganisms.	Figueiredo LC, Freitas Figueiredo N, da Cruz DF, Baccelli GT, Sarachini GE, Bueno MR, Feres M, Bueno-Silva B.	Microorganisms	10.3390/microorganisms10112172	2022
	Metabolic activity of hydro-carbon-oxo-borate on a multispecies subgingival periodontal biofilm: a short communication.	Shibli JA, Rocha TF, Coelho F, de Oliveira Capote TS, Saska S, Melo MA, Pingueiro JMS, de Faveri M, Bueno-Silva B.	Clin Oral Investig	10.1007/s00784-021-03900-0	2021
	Curry Leaf Triggers Cell Death of P. gingivalis with Membrane Blebbing.	Nakao R, Ikeda T, Furukawa S, Morinaga Y.	Pathogens	10.3390/pathogens10101286	2021
Metabolism	Effects of Complex DNA and MVs with GTF Extracted from Streptococcus mutans on the Oral Biofilm.	Senpuku H, Nakamura T, Iwabuchi Y, Hirayama S, Nakao R, Ohnishi M.	Molecules	10.3390/molecules24173131	2019
Phylogeny	Microbiota analysis optimization for human bronchoalveolar lavage fluid.	Schneeberger PHH, Prescod J, Levy L, Hwang D, Martinu T, Coburn B.	Microbiome	10.1186/s40168-019-0755-x	2019
	Dual Inhibitory Activity of Petroselinic Acid Enriched in Fennel Against Porphyromonas gingivalis.	Yoshino N, Ikeda T, Nakao R.	Front Microbiol	10.3389/fmicb.2022.816047	2022
	PCR-Based Identification of Oral Streptococcal Species.	Banas JA, Zhu M, Dawson DV, Cao H, Levy SM.	Int J Dent	10.1155/2016/3465163	2016
Enzymology	Development of real-time PCR assays for detection of the Streptococcus milleri group from cystic fibrosis clinical specimens by targeting the cpn60 and 16S rRNA genes.	Olson AB, Sibley CD, Schmidt L, Wilcox MA, Surette MG, Corbett CR.	J Clin Microbiol	10.1128/jcm.02082-09	2010
Phylogeny	Rapid differentiation between members of the anginosus group and Streptococcus dysgalactiae subsp. equisimilis within beta-hemolytic group C and G streptococci by PCR.	Liu LC, Tsai JC, Hsueh PR, Teng LJ.	J Clin Microbiol	10.1128/jcm.44.5.1836-1838.2006	2006
Enzymology	Microbial diversity similarities in periodontal pockets and atheromatous plaques of cardiovascular disease patients.	Serra e Silva Filho W, Casarin RC, Nicolela EL, Passos HM, Sallum AW, Goncalves RB.	PLoS One	10.1371/journal.pone.0109761	2014
	Modulation of Neutrophil Extracellular Trap and Reactive Oxygen Species Release by Periodontal Bacteria.	Hirschfeld J, White PC, Milward MR, Cooper PR, Chapple ILC.	Infect Immun	10.1128/iai.00297-17	2017
Phylogeny	Use of groESL as a target for identification of Abiotrophia, Granulicatella, and Gemella species.	Hung WC, Tseng SP, Chen HJ, Tsai JC, Chang CH, Lee TF, Hsueh PR, Teng LJ.	J Clin Microbiol	10.1128/jcm.00787-10	2010
Phylogeny	Evaluation of genotypic and phenotypic methods for differentiation of the members of the Anginosus group streptococci.	Summanen PH, Rowlinson MC, Wooton J, Finegold SM.	Eur J Clin Microbiol Infect Dis	10.1007/s10096-009-0758-9	2009
	Horizontal transfer of segments of the 16S rRNA genes between species of the Streptococcus anginosus group.	Schouls LM, Schot CS, Jacobs JA.	J Bacteriol	10.1128/jb.185.24.7241-7246.2003	2003
Pathogenicity	Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients.	Grinwis ME, Sibley CD, Parkins MD, Eshaghurshan CS, Rabin HR, Surette MG.	Antimicrob Agents Chemother	10.1128/aac.01845-09	2010
	Codon-optimized fluorescent mTFP and mCherry for microscopic visualization and genetic counterselection of streptococci and enterococci.	Vickerman MM, Mansfield JM, Zhu M, Walters KS, Banas JA.	J Microbiol Methods	10.1016/j.mimet.2015.06.010	2015
Phylogeny	Genotyping by amplified fragment length polymorphism analysis reveals persistence and recurrence of infection with Streptococcus anginosus group organisms.	Jacobs JA, Tjhie JH, Smeets MG, Schot CS, Schouls LM.	J Clin Microbiol	10.1128/jcm.41.7.2862-2866.2003	2003
	Effects of azithromycin, metronidazole, amoxicillin, and metronidazole plus amoxicillin on an in vitro polymicrobial subgingival biofilm model.	Soares GM, Teles F, Starr JR, Feres M, Patel M, Martin L, Teles R.	Antimicrob Agents Chemother	10.1128/aac.04974-14	2015
Phylogeny	Identification of clinically relevant viridans streptococci by an oligonucleotide array.	Chen CC, Teng LJ, Kaiung S, Chang TC.	J Clin Microbiol	10.1128/jcm.43.4.1515-1521.2005	2005
Metabolism	Enterococcus faecalis enhances cell proliferation through hydrogen peroxide-mediated epidermal growth factor receptor activation.	Boonanantanasarn K, Gill AL, Yap Y, Jayaprakash V, Sullivan MA, Gill SR.	Infect Immun	10.1128/iai.00479-12	2012
	Antibiotic susceptibilities of genetically characterized Streptococcus milleri group strains.	Tracy M, Wanahita A, Shuhatovich Y, Goldsmith EA, Clarridge JE, Musher DM.	Antimicrob Agents Chemother	10.1128/aac.45.5.1511-1514.2001	2001
Phylogeny	Impact of 16S rRNA gene sequence analysis for identification of bacteria on clinical microbiology and infectious diseases.	Clarridge JE.	Clin Microbiol Rev	10.1128/cmr.17.4.840-862.2004	2004
Phylogeny	Identification of "Streptococcus milleri" group isolates to the species level with a commercially available rapid test system.	Flynn CE, Ruoff KL.	J Clin Microbiol	10.1128/jcm.33.10.2704-2706.1995	1995
Phylogeny	Identification of clinically relevant viridans group streptococci to the species level by PCR.	Garnier F, Gerbaud G, Courvalin P, Galimand M.	J Clin Microbiol	10.1128/jcm.35.9.2337-2341.1997	1997
Phylogeny	Characterization of Streptococcus milleri group isolates from expectorated sputum of adult patients with cystic fibrosis.	Grinwis ME, Sibley CD, Parkins MD, Eshaghurshan CS, Rabin HR, Surette MG.	J Clin Microbiol	10.1128/jcm.01807-09	2010
Phylogeny	groESL sequence determination, phylogenetic analysis, and species differentiation for viridans group streptococci.	Teng LJ, Hsueh PR, Tsai JC, Chen PW, Hsu JC, Lai HC, Lee CN, Ho SW.	J Clin Microbiol	10.1128/jcm.40.9.3172-3178.2002	2002
Phylogeny	PCR assay for species-specific identification of Bacteroides thetaiotaomicron.	Teng LJ, Hsueh PR, Tsai JC, Chiang FL, Chen CY, Ho SW, Luh KT.	J Clin Microbiol	10.1128/jcm.38.4.1672-1675.2000	2000
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Enzymology	Development of a rapid PCR assay specific for Staphylococcus saprophyticus and application to direct detection from urine samples.	Martineau F, Picard FJ, Menard C, Roy PH, Ouellette M, Bergeron MG.	J Clin Microbiol	10.1128/jcm.38.9.3280-3284.2000	2000
Enzymology	Multiplex PCR assay for detection of Streptococcus suis species and serotypes 2 and 1/2 in tonsils of live and dead pigs.	Marois C, Bougeard S, Gottschalk M, Kobisch M.	J Clin Microbiol	10.1128/jcm.42.7.3169-3175.2004	2004
Phylogeny	Staph ID/R: a rapid method for determining staphylococcus species identity and detecting the mecA gene directly from positive blood culture.	Pasko C, Hicke B, Dunn J, Jaeckel H, Nieuwlandt D, Weed D, Woodruff E, Zheng X, Jenison R.	J Clin Microbiol	10.1128/jcm.05534-11	2012
Phylogeny	Development of a PCR assay for identification of staphylococci at genus and species levels.	Martineau F, Picard FJ, Ke D, Paradis S, Roy PH, Ouellette M, Bergeron MG.	J Clin Microbiol	10.1128/jcm.39.7.2541-2547.2001	2001
	Streptococcus salivarius fimbriae are composed of a glycoprotein containing a repeated motif assembled into a filamentous nondissociable structure.	Levesque C, Vadeboncoeur C, Chandad F, Frenette M.	J Bacteriol	10.1128/jb.183.9.2724-2732.2001	2001
Enzymology	Rapid concentration and molecular enrichment approach for sensitive detection of Escherichia coli and Shigella species in potable water samples.	Maheux AF, Bissonnette L, Boissinot M, Bernier JL, Huppe V, Picard FJ, Berube E, Bergeron MG.	Appl Environ Microbiol	10.1128/aem.02337-10	2011
	Development of a PCR assay for rapid detection of enterococci.	Ke D, Picard FJ, Martineau F, Menard C, Roy PH, Ouellette M, Bergeron MG.	J Clin Microbiol	10.1128/jcm.37.11.3497-3503.1999	1999
	Detection of 11 common viral and bacterial pathogens causing community-acquired pneumonia or sepsis in asymptomatic patients by using a multiplex reverse transcription-PCR assay with manual (enzyme hybridization) or automated (electronic microarray) detection.	Kumar S, Wang L, Fan J, Kraft A, Bose ME, Tiwari S, Van Dyke M, Haigis R, Luo T, Ghosh M, Tang H, Haghnia M, Mather EL, Weisburg WG, Henrickson KJ.	J Clin Microbiol	10.1128/jcm.00625-08	2008
Pathogenicity	New real-time PCR assay for rapid detection of methicillin-resistant Staphylococcus aureus directly from specimens containing a mixture of staphylococci.	Huletsky A, Giroux R, Rossbach V, Gagnon M, Vaillancourt M, Bernier M, Gagnon F, Truchon K, Bastien M, Picard FJ, van Belkum A, Ouellette M, Roy PH, Bergeron MG.	J Clin Microbiol	10.1128/jcm.42.5.1875-1884.2004	2004
	Rapid identification of mycobacteria and drug-resistant Mycobacterium tuberculosis by use of a single multiplex PCR and DNA sequencing.	Perez-Osorio AC, Boyle DS, Ingham ZK, Ostash A, Gautom RK, Colombel C, Houze Y, Leader BT.	J Clin Microbiol	10.1128/jcm.05570-11	2012
Enzymology	Distribution of proteins similar to IIIManH and IIIManL of the Streptococcus salivarius phosphoenolpyruvate:mannose-glucose phosphotransferase system among oral and nonoral bacteria.	Pelletier M, Frenette M, Vadeboncoeur C.	J Bacteriol	10.1128/jb.177.9.2270-2275.1995	1995
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Cultivation	A simple, semiselective medium for anaerobic isolation of anginosus group streptococci from patients with chronic lung disease.	Waite RD, Wareham DW, Gardiner S, Whiley RA.	J Clin Microbiol	10.1128/jcm.06184-11	2012
Genetics	Bacteriocin Producing Streptococcus agalactiae Strains Isolated from Bovine Mastitis in Brazil.	Vidal Amaral JR, Juca Ramos RT, Almeida Araujo F, Bentes Kato R, Figueira Aburjaile F, de Castro Soares S, Goes-Neto A, Matiuzzi da Costa M, Azevedo V, Brenig B, Soares de Oliveira S, Soares Rosado A.	Microorganisms	10.3390/microorganisms10030588	2022
	Genomic and phenotypic characterization of Streptococcus mutans isolates suggests key gene clusters in regulating its interaction with Streptococcus gordonii.	Liu S, Sun Y, Liu Y, Hu F, Xu L, Zheng Q, Wang Q, Zeng G, Zhang K.	Front Microbiol	10.3389/fmicb.2022.945108	2022
Phylogeny	Use of quantitative PCR and culture methods to characterize ecological flux in bacterial biofilms.	Dalwai F, Spratt DA, Pratten J.	J Clin Microbiol	10.1128/jcm.01131-07	2007
	Streptococcus pneumoniae potently induces cell death in mesothelial cells.	Rashwan R, Varano Della Vergiliana JF, Lansley SM, Cheah HM, Popowicz N, Paton JC, Waterer GW, Townsend T, Kay I, Brown JS, Lee YCG.	PLoS One	10.1371/journal.pone.0201530	2018
	Identification of the psaA gene, coding for pneumococcal surface adhesin A, in viridans group streptococci other than Streptococcus pneumoniae.	Jado I, Fenoll A, Casal J, Perez A.	Clin Diagn Lab Immunol	10.1128/cdli.8.5.895-898.2001	2001
Enzymology	Chondroitin sulfate depolymerase and hyaluronidase activities of viridans streptococci determined by a sensitive spectrophotometric assay.	Homer KA, Denbow L, Whiley RA, Beighton D.	J Clin Microbiol	10.1128/jcm.31.6.1648-1651.1993	1993
	Eight-plex PCR and liquid-array detection of bacterial and viral pathogens in cerebrospinal fluid from patients with suspected meningitis.	Boving MK, Pedersen LN, Moller JK.	J Clin Microbiol	10.1128/jcm.01966-08	2009
	Coaggregation of Streptococcus sanguis and other streptococci with Candida albicans.	Jenkinson HF, Lala HC, Shepherd MG.	Infect Immun	10.1128/iai.58.5.1429-1436.1990	1990
Phylogeny	Simple genetic method to identify viridans group streptococci by colorimetric dot hybridization and fluorometric hybridization in microdilution wells.	Ezaki T, Hashimoto Y, Takeuchi N, Yamamoto H, Liu SL, Miura H, Matsui K, Yabuuchi E.	J Clin Microbiol	10.1128/jcm.26.9.1708-1713.1988	1988
Phylogeny	Species identification of members of the Streptococcus milleri group isolated from the vagina by ID 32 Strep system and differential phenotypic characteristics.	Ahmet Z, Warren M, Houang ET.	J Clin Microbiol	10.1128/jcm.33.6.1592-1595.1995	1995
Phylogeny	Sequetyping: serotyping Streptococcus pneumoniae by a single PCR sequencing strategy.	Leung MH, Bryson K, Freystatter K, Pichon B, Edwards G, Charalambous BM, Gillespie SH.	J Clin Microbiol	10.1128/jcm.06384-11	2012
Enzymology	Sialidase activity of the "Streptococcus milleri group" and other viridans group streptococci.	Beighton D, Whiley RA.	J Clin Microbiol	10.1128/jcm.28.6.1431-1433.1990	1990
	Streptococcus pneumoniae autolysis prevents phagocytosis and production of phagocyte-activating cytokines.	Martner A, Skovbjerg S, Paton JC, Wold AE.	Infect Immun	10.1128/iai.00290-09	2009
Phylogeny	Comparison of phenotypic characteristics, DNA-DNA hybridization results, and results with a commercial rapid biochemical and enzymatic reaction system for identification of viridans group streptococci.	Kikuchi K, Enari T, Totsuka K, Shimizu K.	J Clin Microbiol	10.1128/jcm.33.5.1215-1222.1995	1995
	Compilation of small ribosomal subunit RNA structures.	Neefs JM, Van de Peer Y, De Rijk P, Chapelle S, De Wachter R.	Nucleic Acids Res	10.1093/nar/21.13.3025	1993
	Natural cinnamic acids, synthetic derivatives and hybrids with antimicrobial activity.	Guzman JD.	Molecules	10.3390/molecules191219292	2014
Pathogenicity	Community Composition Determines Activity of Antibiotics against Multispecies Biofilms.	Tavernier S, Crabbe A, Hacioglu M, Stuer L, Henry S, Rigole P, Dhondt I, Coenye T.	Antimicrob Agents Chemother	10.1128/aac.00302-17	2017
Pathogenicity	Developing selective media for quantification of multispecies biofilms following antibiotic treatment.	Vandeplassche E, Coenye T, Crabbe A.	PLoS One	10.1371/journal.pone.0187540	2017
Metabolism	Reactivation of latent HIV-1 by a wide variety of butyric acid-producing bacteria.	Imai K, Yamada K, Tamura M, Ochiai K, Okamoto T.	Cell Mol Life Sci	10.1007/s00018-012-0936-2	2012
	beta-Hemolytic Streptococcus anginosus subsp. anginosus causes streptolysin S-dependent cytotoxicity to human cell culture lines in vitro.	Tabata A, Yamada T, Ohtani H, Ohkura K, Tomoyasu T, Nagamune H	J Oral Microbiol	10.1080/20002297.2019.1609839	2019
Metabolism	The fibronectin-binding protein homologue Fbp62 of Streptococcus anginosus is a potent virulence factor.	Kodama Y, Ishikawa T, Shimoyama Y, Sasaki D, Kimura S, Sasaki M	Microbiol Immunol	10.1111/1348-0421.12646	2018
Metabolism	Aciduricity and acid tolerance mechanisms of Streptococcus anginosus.	Sasaki M, Kodama Y, Shimoyama Y, Ishikawa T, Kimura S	J Gen Appl Microbiol	10.2323/jgam.2017.11.005	2018
Pathogenicity	Identification of beta-haemolysin-encoding genes in Streptococcus anginosus.	Asam D, Mauerer S, Walheim E, Spellerberg B	Mol Oral Microbiol	10.1111/omi.12026	2013
Pathogenicity	The efficacy of povidone-iodine products against periodontopathic bacteria.	Nakagawa T, Hosaka Y, Ishihara K, Hiraishi T, Sato S, Ogawa T, Kamoi K	Dermatology	10.1159/000089208	2006
Enzymology	Dipeptidyl peptidase IV of Streptococcus anginosus: purification and characterization.	Fujimura S, Shibata Y, Hirai K, Ueda O	Eur J Med Res		2005
Metabolism	Antigenic characterisation of a novel Streptococcus anginosus antigen that induces nitric oxide synthesis by murine peritoneal exudate cells.	Sasaki M, Ohara-Nemoto Y, Tajika S, Kobayashi M, Yamaura C, Kimura S	J Med Microbiol	10.1099/0022-1317-50-11-952	2001
Phylogeny	The Streptococcus anginosus species comprises five 16S rRNA ribogroups with different phenotypic characteristics and clinical relevance.	Jacobs JA, Schot CS, Schouls LM	Int J Syst Evol Microbiol	10.1099/00207713-50-3-1073	2000
Phylogeny	Rapid species identification of "Streptococcus milleri" strains by line blot hybridization: identification of a distinct 16S rRNA population closely related to Streptococcus constellatus.	Jacobs JA, Schot CS, Bunschoten AE, Schouls LM	J Clin Microbiol	10.1128/JCM.34.7.1717-1721.1996	1996
Phylogeny	Deoxyribonucleic acid relatedness and phenotypic characteristics of oral Streptococcus milleri strains.	Taketoshi M, Yakushiji T, Inoue M	Microbios		1993
Pathogenicity	Emended descriptions and recognition of Streptococcus constellatus, Streptococcus intermedius, and Streptococcus anginosus as distinct species.	Whiley RA, Beighton D	Int J Syst Bacteriol	10.1099/00207713-41-1-1	1991
Pathogenicity	Serogrouping of oral Streptococcus intermedius.	Osano E, Tanaka T, Ozeki M, Makita I, Moriyama T	Microbiol Immunol		1990
Phylogeny	DNA-DNA hybridization studies and phenotypic characteristics of strains within the 'Streptococcus milleri group'.	Whiley RA, Hardie JM	J Gen Microbiol	10.1099/00221287-135-10-2623	1989
Pathogenicity	[Taxonomic studies of the Streptococcus intermedius strains isolated from human oral cavities].	Fujii Y	Aichi Gakuin Daigaku Shigakkai Shi		1989
	Streptococcus atopica sp. nov., Isolated from the Feces of a Toddler with Atopic Dermatitis.	Chan CK, Wu HS, Tsai LJ, Lee YS, Chang YC, Wu HC, Chen YS.	Curr Microbiol	10.1007/s00284-025-04529-y	2025
Phylogeny	Streptococcus vaginalis sp. nov., a novel bacterial species isolated from vaginal swabs of a pregnant woman with diabetes.	Chao AS, Lin CY, Chao A, Lee YS, Chang YC, Wu HC, Dai YJ, Liao WQ, Kao FC, Chen YS	Arch Microbiol	10.1007/s00203-021-02532-y	2021
Phylogeny	Streptococcus periodonticum sp. nov., Isolated from Human Subgingival Dental Plaque of Periodontitis Lesion.	Lim YK, Park SN, Shin JH, Chang YH, Shin Y, Paek J, Kim H, Kook JK	Curr Microbiol	10.1007/s00284-019-01695-8	2019
Phylogeny	A study of small-colony, beta-haemolytic, Lancefield group C streptococci within the anginosus group: description of Streptococcus constellatus subsp. pharyngis subsp. nov., associated with the human throat and pharyngitis.	Whiley RA, Hall LM, Hardie JM, Beighton D	Int J Syst Bacteriol	10.1099/00207713-49-4-1443	1999

References

#8913	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 20563
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#41326	; Curators of the CIP;
#48705	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 27298
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#66793	Mukherjee et al.: GEBA: 1,003 reference genomes of bacterial and archaeal isolates expand coverage of the tree of life. 35: 676 - 683 2017 ( DOI 10.1038/nbt.3886 , PubMed 28604660 )
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68371	Automatically annotated from API 50CH acid .
#68381	Automatically annotated from API rID32STR .
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#116383	Collection of Institut Pasteur ; Curators of the CIP; CIP 102921
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Streptococcus anginosus subsp. anginosus (DSM 20563, ATCC 12395, ATCC 33397)

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