Streptococcus agalactiae CCUG 29784 is a prokaryote of the family Streptococcaceae.
genome sequence| @ref 20215 |
Last LPSN update
2026-02-09 11:35:12 |
| Domain Bacteria |
| Phylum Bacillota |
| Class Bacilli |
| Order Lactobacillales |
| Family Streptococcaceae |
| Genus Streptococcus |
| Species Streptococcus agalactiae |
| Full scientific name Streptococcus agalactiae Lehmann and Neumann 1896 (Approved Lists 1980) |
| Synonyms (2) |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 124043 | ASM78285v1 assembly for Streptococcus agalactiae CNCTC 10/84 | complete | GCA_000782855   | 1427374.3  | 2627854227  | 1427374 | 99.56 |  |
| 124043 | ASM3007831v1 assembly for Streptococcus agalactiae CNCTC 10/84 sCas9revertant | complete | GCA_030078315 | 1311.5376 | 1311 | 99.45 | | |
| 124043 | ASM3007823v1 assembly for Streptococcus agalactiae CNCTC 10/84 dCas9 | complete | GCA_030078235 | 1311.5379 | 1311 | 99.39 | | |
| 124043 | ASM3007829v1 assembly for Streptococcus agalactiae CNCTC 10/84 sCas9 | complete | GCA_030078295 | 1311.5375 | 1311 | 99.39 | | |
| 124043 | ASM3007835v1 assembly for Streptococcus agalactiae CNCTC 10/84 Cas9 AEKOrevertant | complete | GCA_030078355 | 1311.5382 | 1311 | 99.39 | | |
| 124043 | ASM3007837v1 assembly for Streptococcus agalactiae CNCTC 10/84 Cas9 AEKO | complete | GCA_030078375 | 1311.5405 | 1311 | 99.39 | |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| The Streptococcus agalactiae R3 surface protein is encoded by sar5. | Basson A, Olaisen C, Selvik LK, Lyng RV, Lysvand H, Gidon A, Aas CG, Afset JE, Dragset MS. | PLoS One | 10.1371/journal.pone.0263199 | 2022 | | |
| Genetics | A Cas12a Toolbox for Rapid and Flexible Group B Streptococcus Genomic Editing and CRISPRi. | Hillebrand GH, Carlin SC, Giacobe EJ, Stephenson HA, Collins J, Hooven TA. | Mol Microbiol | 10.1111/mmi.70022 | 2025 | |
| Pathogenicity | A CRISPRi library screen in group B Streptococcus identifies surface immunogenic protein (Sip) as a mediator of multiple host interactions. | Firestone K, Gopalakrishna KP, Rogers LM, Peters A, Gaddy JA, Nichols CM, Hall MH, Varela HN, Carlin SM, Hillebrand GH, Giacobe EJ, Aronoff DM, Hooven TA. | Infect Immun | 10.1128/iai.00573-24 | 2025 | |
| Heterogeneity of the group B streptococcal type VII secretion system and influence on colonization of the female genital tract. | Spencer BL, Job AM, Robertson CM, Hameed ZA, Serchejian C, Wiafe-Kwakye CS, Mendonca JC, Apolonio MA, Nagao PE, Neely MN, Korotkova N, Korotkov KV, Patras KA, Doran KS. | Mol Microbiol | 10.1111/mmi.15115 | 2023 | | |
| Genetics | Comparative Genomic Analysis of Prophages in Human Vaginal Isolates of Streptococcus agalactiae. | Wiafe-Kwakye CS, Fournier A, Maurais H, Southworth KJ, Molloy SD, Neely MN. | Pathogens | 10.3390/pathogens13080610 | 2024 | |
| Nitric Oxide Production and Effects in Group B Streptococcus Chorioamnionitis. | Keith MF, Gopalakrishna KP, Bhavana VH, Hillebrand GH, Elder JL, Megli CJ, Sadovsky Y, Hooven TA. | Pathogens | 10.3390/pathogens11101115 | 2022 | | |
| Modulation of group B Streptococcus infection and vaginal cell inflammatory signaling in vitro by Lactobacillus crispatus-loaded electrospun fibers. | El-Baz N, Kyser A, Mahmoud MY, Farrell CZ, Ginocchio S, Frieboes HB, Doster RS. | Infect Immun | 10.1128/iai.00170-25 | 2025 | | |
| Group B Streptococcus Cas9 variants provide insight into programmable gene repression and CRISPR-Cas transcriptional effects. | Gopalakrishna KP, Hillebrand GH, Bhavana VH, Elder JL, D'Mello A, Tettelin H, Hooven TA. | Commun Biol | 10.1038/s42003-023-04994-w | 2023 | | |
| Gamma-Irradiated Non-Capsule Group B Streptococcus Promotes T-Cell Dependent Immunity and Provides a Cross-Protective Reaction. | Zhi Y, Chen F, Cao G, Li F. | Pharmaceuticals (Basel) | 10.3390/ph16020321 | 2023 | | |
| Genome-Wide Assessment of Streptococcus agalactiae Genes Required for Survival in Human Whole Blood and Plasma. | Zhu L, Yerramilli P, Pruitt L, Ojeda Saavedra M, Cantu CC, Olsen RJ, Beres SB, Waller AS, Musser JM. | Infect Immun | 10.1128/iai.00357-20 | 2020 | | |
| Metabolism | Identification of a novel cationic glycolipid in Streptococcus agalactiae that contributes to brain entry and meningitis. | Joyce LR, Manzer HS, da C Mendonca J, Villarreal R, Nagao PE, Doran KS, Palmer KL, Guan Z. | PLoS Biol | 10.1371/journal.pbio.3001555 | 2022 | |
| Metabolism | Fructose promotes ampicillin killing of antibiotic-resistant Streptococcus agalactiae. | Chen XW, Wu JH, Liu YL, Munang'andu HM, Peng B. | Virulence | 10.1080/21505594.2023.2180938 | 2023 | |
| Pathogenicity | A group B streptococcal type VII-secreted LXG toxin mediates interbacterial competition and colonization of the murine female genital tract. | Job AM, Doran KS, Spencer BL. | mBio | 10.1128/mbio.02088-24 | 2024 | |
| Gestational diabetes augments group B Streptococcus infection by disrupting maternal immunity and the vaginal microbiota. | Mercado-Evans V, Mejia ME, Zulk JJ, Ottinger S, Hameed ZA, Serchejian C, Marunde MG, Robertson CM, Ballard MB, Ruano SH, Korotkova N, Flores AR, Pennington KA, Patras KA. | Nat Commun | 10.1038/s41467-024-45336-6 | 2024 | | |
| The S Protein of Group B Streptococcus Is a Critical Virulence Determinant That Impacts the Cell Surface Virulome. | Campeau A, Uchiyama S, Sanchez C, Sauceda C, Nizet V, Gonzalez DJ. | Front Microbiol | 10.3389/fmicb.2021.729308 | 2021 | | |
| Genetics | Bacteriocin Producing Streptococcus agalactiae Strains Isolated from Bovine Mastitis in Brazil. | Vidal Amaral JR, Juca Ramos RT, Almeida Araujo F, Bentes Kato R, Figueira Aburjaile F, de Castro Soares S, Goes-Neto A, Matiuzzi da Costa M, Azevedo V, Brenig B, Soares de Oliveira S, Soares Rosado A. | Microorganisms | 10.3390/microorganisms10030588 | 2022 | |
| Pathogenicity | The Diverse Antimicrobial Activities of Human Milk Oligosaccharides against Group B Streptococcus. | Moore RE, Townsend SD, Gaddy JA. | Chembiochem | 10.1002/cbic.202100423 | 2022 | |
| Group B Streptococcal Colonization in African Countries: Prevalence, Capsular Serotypes, and Molecular Sequence Types. | Shabayek S, Ferrieri P, Spellerberg B. | Pathogens | 10.3390/pathogens10121606 | 2021 | | |
| Metabolism | A type VII secretion system in Group B Streptococcus mediates cytotoxicity and virulence. | Spencer BL, Tak U, Mendonca JC, Nagao PE, Niederweis M, Doran KS. | PLoS Pathog | 10.1371/journal.ppat.1010121 | 2021 | |
| Improving the Sensitivity of Real-time PCR Detection of Group B Streptococcus Using Consensus Sequence-Derived Oligonucleotides. | Khatami A, Randis TM, Chamby A, Hooven TA, Gegick M, Suzman E, A'Hearn-Thomas B, Steenhoff AP, Ratner AJ. | Open Forum Infect Dis | 10.1093/ofid/ofy164 | 2018 | | |
| Group B Streptococcus Biofilm Regulatory Protein A Contributes to Bacterial Physiology and Innate Immune Resistance. | Patras KA, Derieux J, Al-Bassam MM, Adiletta N, Vrbanac A, Lapek JD, Zengler K, Gonzalez DJ, Nizet V. | J Infect Dis | 10.1093/infdis/jiy341 | 2018 | | |
| Metabolism | A Counterselectable Sucrose Sensitivity Marker Permits Efficient and Flexible Mutagenesis in Streptococcus agalactiae. | Hooven TA, Bonakdar M, Chamby AB, Ratner AJ. | Appl Environ Microbiol | 10.1128/aem.03009-18 | 2019 | |
| Vaccination With a Latch Peptide Provides Serotype-Independent Protection Against Group B Streptococcus Infection in Mice. | Lin SM, Jang AY, Zhi Y, Gao S, Lim S, Lim JH, Song JY, Sullam PM, Rhee JH, Seo HS. | J Infect Dis | 10.1093/infdis/jix565 | 2017 | | |
| Pathogenicity | A Solution to Antifolate Resistance in Group B Streptococcus: Untargeted Metabolomics Identifies Human Milk Oligosaccharide-Induced Perturbations That Result in Potentiation of Trimethoprim. | Chambers SA, Moore RE, Craft KM, Thomas HC, Das R, Manning SD, Codreanu SG, Sherrod SD, Aronoff DM, McLean JA, Gaddy JA, Townsend SD. | mBio | 10.1128/mbio.00076-20 | 2020 | |
| Pathogenicity | Antimicrobial and Antibiofilm Activity of Human Milk Oligosaccharides against Streptococcus agalactiae, Staphylococcus aureus, and Acinetobacter baumannii. | Ackerman DL, Craft KM, Doster RS, Weitkamp JH, Aronoff DM, Gaddy JA, Townsend SD. | ACS Infect Dis | 10.1021/acsinfecdis.7b00183 | 2018 | |
| Mucosal vaccination promotes clearance of Streptococcus agalactiae vaginal colonization. | Baker JA, Lewis EL, Byland LM, Bonakdar M, Randis TM, Ratner AJ. | Vaccine | 10.1016/j.vaccine.2017.01.029 | 2017 | | |
| Raman microspectroscopy differentiates perinatal pathogens on ex vivo infected human fetal membrane tissues. | Ayala OD, Doster RS, Manning SD, O'Brien CM, Aronoff DM, Gaddy JA, Mahadevan-Jansen A. | J Biophotonics | 10.1002/jbio.201800449 | 2019 | | |
| Group B streptococcal infections in pregnancy and early life. | Manuel G, Twentyman J, Noble K, Eastman AJ, Aronoff DM, Seepersaud R, Rajagopal L, Adams Waldorf KM. | Clin Microbiol Rev | 10.1128/cmr.00154-22 | 2025 | | |
| Metabolism | Genome-Wide fitness analysis of group B Streptococcus in human amniotic fluid reveals a transcription factor that controls multiple virulence traits. | Dammann AN, Chamby AB, Catomeris AJ, Davidson KM, Tettelin H, van Pijkeren JP, Gopalakrishna KP, Keith MF, Elder JL, Ratner AJ, Hooven TA. | PLoS Pathog | 10.1371/journal.ppat.1009116 | 2021 | |
| Pathogenicity | Human Milk Oligosaccharides Exhibit Antimicrobial and Antibiofilm Properties against Group B Streptococcus. | Ackerman DL, Doster RS, Weitkamp JH, Aronoff DM, Gaddy JA, Townsend SD. | ACS Infect Dis | 10.1021/acsinfecdis.7b00064 | 2017 | |
| Genetics | Genomic Insights Into the Distribution and Evolution of Group B Streptococcus. | Chen SL. | Front Microbiol | 10.3389/fmicb.2019.01447 | 2019 | |
| Pathogenicity | Host inflammatory dynamics reveal placental immune modulation by Group B Streptococcus during pregnancy. | Kuperwaser F, Avital G, Vaz MJ, Noble KN, Dammann AN, Randis TM, Aronoff DM, Ratner AJ, Yanai I. | Mol Syst Biol | 10.15252/msb.202211021 | 2023 | |
| In Love with Shaping You-Influential Factors on the Breast Milk Content of Human Milk Oligosaccharides and Their Decisive Roles for Neonatal Development. | Hundshammer C, Minge O. | Nutrients | 10.3390/nu12113568 | 2020 | | |
| Metabolism | beta-Hemolysin/cytolysin of Group B Streptococcus enhances host inflammation but is dispensable for establishment of urinary tract infection. | Kulkarni R, Randis TM, Antala S, Wang A, Amaral FE, Ratner AJ. | PLoS One | 10.1371/journal.pone.0059091 | 2013 | |
| Genetics | Changing molecular epidemiology of group B streptococcus in Korea. | Seo YS, Srinivasan U, Oh KY, Shin JH, Chae JD, Kim MY, Yang JH, Yoon HR, Miller B, DeBusscher J, Foxman B, Ki M. | J Korean Med Sci | 10.3346/jkms.2010.25.6.817 | 2010 | |
| Metabolism | Abundance of the delta subunit of RNA polymerase is linked to the virulence of Streptococcus agalactiae. | Seepersaud R, Needham RH, Kim CS, Jones AL. | J Bacteriol | 10.1128/jb.188.6.2096-2105.2006 | 2006 | |
| Phylogeny | Comparison of DNA dot blot hybridization and lancefield capillary precipitin methods for group B streptococcal capsular typing. | Borchardt SM, Foxman B, Chaffin DO, Rubens CE, Tallman PA, Manning SD, Baker CJ, Marrs CF. | J Clin Microbiol | 10.1128/jcm.42.1.146-150.2004 | 2004 | |
| Phylogeny | Typing of group B streptococci: comparison of pulsed-field gel electrophoresis and conventional electrophoresis. | Gordillo ME, Singh KV, Baker CJ, Murray BE. | J Clin Microbiol | 10.1128/jcm.31.6.1430-1434.1993 | 1993 | |
| Phylogeny | Genotyping of the capsule gene cluster (cps) in nontypeable group B streptococci reveals two major cps allelic variants of serotypes III and VII. | Sellin M, Olofsson C, Hakansson S, Norgren M. | J Clin Microbiol | 10.1128/jcm.38.9.3420-3428.2000 | 2000 | |
| Antimicrobial Activities of Alginate and Chitosan Oligosaccharides Against Staphylococcus aureus and Group B Streptococcus. | Asadpoor M, Ithakisiou GN, van Putten JPM, Pieters RJ, Folkerts G, Braber S. | Front Microbiol | 10.3389/fmicb.2021.700605 | 2021 | | |
| Pathogenicity | Antibiotic resistance of Streptococcus agalactiae isolated from pregnant women in Garankuwa, South Africa. | Bolukaoto JY, Monyama CM, Chukwu MO, Lekala SM, Nchabeleng M, Maloba MR, Mavenyengwa RT, Lebelo SL, Monokoane ST, Tshepuwane C, Moyo SR. | BMC Res Notes | 10.1186/s13104-015-1328-0 | 2015 | |
| Metabolism | Group B streptococcal infection and activation of human astrocytes. | Stoner TD, Weston TA, Trejo J, Doran KS. | PLoS One | 10.1371/journal.pone.0128431 | 2015 | |
| Survey of immunological features of the alpha-like proteins of Streptococcus agalactiae. | Maeland JA, Afset JE, Lyng RV, Radtke A. | Clin Vaccine Immunol | 10.1128/cvi.00643-14 | 2015 | | |
| Streptococcus salivarius K12 Limits Group B Streptococcus Vaginal Colonization. | Patras KA, Wescombe PA, Rosler B, Hale JD, Tagg JR, Doran KS. | Infect Immun | 10.1128/iai.00409-15 | 2015 | | |
| Phylogeny | Distinctive features of surface-anchored proteins of Streptococcus agalactiae strains from Zimbabwe revealed by PCR and dot blotting. | Mavenyengwa RT, Maeland JA, Moyo SR. | Clin Vaccine Immunol | 10.1128/cvi.00112-08 | 2008 | |
| Metabolism | Group B Streptococcus beta-hemolysin/cytolysin breaches maternal-fetal barriers to cause preterm birth and intrauterine fetal demise in vivo. | Randis TM, Gelber SE, Hooven TA, Abellar RG, Akabas LH, Lewis EL, Walker LB, Byland LM, Nizet V, Ratner AJ. | J Infect Dis | 10.1093/infdis/jiu067 | 2014 | |
| Pathogenicity | A novel C5a-derived immunobiotic peptide reduces Streptococcus agalactiae colonization through targeted bacterial killing. | Cavaco CK, Patras KA, Zlamal JE, Thoman ML, Morgan EL, Sanderson SD, Doran KS. | Antimicrob Agents Chemother | 10.1128/aac.01590-13 | 2013 | |
| Phylogeny | Evaluation of a multiplex PCR-based reverse line blot-hybridization assay for identification of serotype and surface protein antigens of Streptococcus agalactiae. | Zeng X, Kong F, Morgan J, Gilbert GL. | J Clin Microbiol | 10.1128/jcm.01232-06 | 2006 | |
| Metabolism | Drug-Resistant Staphylococcus aureus Strains Reveal Distinct Biochemical Features with Raman Microspectroscopy. | Ayala OD, Wakeman CA, Pence IJ, Gaddy JA, Slaughter JC, Skaar EP, Mahadevan-Jansen A. | ACS Infect Dis | 10.1021/acsinfecdis.8b00029 | 2018 | |
| Reverse line blot assay for direct identification of seven Streptococcus agalactiae major surface protein antigen genes. | Zhao Z, Kong F, Gilbert GL. | Clin Vaccine Immunol | 10.1128/cvi.13.1.145-149.2006 | 2006 | | |
| Metabolism | Serine-rich repeat proteins and pili promote Streptococcus agalactiae colonization of the vaginal tract. | Sheen TR, Jimenez A, Wang NY, Banerjee A, van Sorge NM, Doran KS. | J Bacteriol | 10.1128/jb.00094-11 | 2011 | |
| Antigenic determinants of alpha-like proteins of Streptococcus agalactiae. | Maeland JA, Bevanger L, Lyng RV. | Clin Diagn Lab Immunol | 10.1128/cdli.11.6.1035-1039.2004 | 2004 | | |
| Phylogeny | bca, beta gene, and gene product divergency in reference and prototype strains of streptococcus agalactiae. | Maeland JA, Bevanger L, Iversen G, Lyng RV. | Clin Diagn Lab Immunol | 10.1128/cdli.6.6.986-988.1999 | 1999 | |
| Immunological markers of the R4 protein of Streptococcus agalactiae. | Maeland JA, Bevanger L, Lyng RV. | Clin Diagn Lab Immunol | 10.1128/cdli.12.11.1305-1310.2005 | 2005 | | |
| The group B streptococcal serine-rich repeat 1 glycoprotein mediates penetration of the blood-brain barrier. | van Sorge NM, Quach D, Gurney MA, Sullam PM, Nizet V, Doran KS. | J Infect Dis | 10.1086/598217 | 2009 | | |
| Metabolism | Group B Streptococcus interactions with human meningeal cells and astrocytes in vitro. | Alkuwaity K, Taylor A, Heckels JE, Doran KS, Christodoulides M. | PLoS One | 10.1371/journal.pone.0042660 | 2012 | |
| Heparan Sulfate Modulates Neutrophil and Endothelial Function in Antibacterial Innate Immunity. | Xu D, Olson J, Cole JN, van Wijk XM, Brinkmann V, Zychlinsky A, Nizet V, Esko JD, Chang YC. | Infect Immun | 10.1128/iai.00545-15 | 2015 | | |
| Metabolism | Genetic Basis Underlying the Hyperhemolytic Phenotype of Streptococcus agalactiae Strain CNCTC10/84. | Zhu L, Beres SB, Yerramilli P, Pruitt L, Cantu CC, Olsen RJ, Musser JM | J Bacteriol | 10.1128/JB.00504-20 | 2020 | |
| Metabolism | Molecular characteristics of Streptococcus agalactiae strains deficient in alpha-like protein encoding genes. | Gabrielsen C, Maeland JA, Lyng RV, Radtke A, Afset JE | J Med Microbiol | 10.1099/jmm.0.000412 | 2017 | |
| Genetics | Complete Genome Sequence of Streptococcus agalactiae CNCTC 10/84, a Hypervirulent Sequence Type 26 Strain. | Hooven TA, Randis TM, Daugherty SC, Narechania A, Planet PJ, Tettelin H, Ratner AJ | Genome Announc | 10.1128/genomeA.01338-14 | 2014 | |
| Pathogenicity | Novel aspects of the Z and R3 antigens of Streptococcus agalactiae revealed by immunological testing. | Maeland JA, Radtke A, Lyng RV, Mavenyengwa RT | Clin Vaccine Immunol | 10.1128/CVI.00581-12 | 2013 | |
| Pathogenicity | Putative novel surface-exposed Streptococcus agalactiae protein frequently expressed by the group B streptococcus from Zimbabwe. | Mavenyengwa RT, Maeland JA, Moyo SR | Clin Vaccine Immunol | 10.1128/CVI.00133-09 | 2009 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive145851.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
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