Staphylococcus hyicus subsp. hyicus (DSM 20459, ATCC 11249, CCM 2368)

Name: Staphylococcus hyicus subsp. hyicus (DSM 20459, ATCC 11249, CCM 2368)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 14554

Type strain

Strain Designation 1

Culture col. no. DSM 20459 ATCC 11249 CCM 2368 NCTC 10350 1 9 more

NCBI tax ID(s) 1284

Special Collections DSMZ CCUG JCM CIP

History DSMZ <- K.H. Schleifer <- NCTC <- ATCC <- D. Sompolinsky, 1 (Micrococcus hyicus) JCM <-- R. Sakazaki <-- ATCC 11249 <-- D. Sompolinsky 1. CIP <- 1981, CCM <- ATCC <- D. Sompolinsky: strain 1, Micrococcus hyicus

Links

Staphylococcus hyicus subsp. hyicus 1 is a Gram-positive, coccus-shaped animal pathogen that was isolated from pig with exudative epidermitis.

Gram-positive coccus-shaped animal pathogen genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 264337

LMG 13352,ATCC 11249,CCM 2368,DSM 20459,NCTC 10350,CCUG 6509,CCUG 15602,JCM 2423,CCRC 12925,BCRC 12925,NBIMCC 1094,CIP 81.58,CNCTC 6043

@ref 20215

Last LPSN update 2026-05-29 08:28:19

Domain Bacteria

Phylum Bacillota

Class Bacilli

Order Caryophanales

Family Staphylococcaceae

Genus Staphylococcus

Species Staphylococcus hyicus subsp. hyicus

Full scientific name Staphylococcus hyicus subsp. hyicus (Sompolinsky 1953) Devriese et al. 1978 (Approved Lists 1980)

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Motility
120021	positive	coccus-shaped

Colony morphology

@ref	Type of hemolysis	Hemolysis ability	Incubation period
8830	gamma	0	1-2 days
120021		1

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
8830	COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)	Medium recipe at MediaDive	Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
8830	TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)	Medium recipe at MediaDive	Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water
37621	MEDIUM 3 - Columbia agar		Columbia agar (39.000 g);distilled water (1000.000 ml)
120021	CIP Medium 3	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
8830	positive	growth	37
37621	positive	growth	37
67770	positive	growth	26
120021	positive	growth	37

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
125439	facultative anaerobe	90.572

Spore formation

@ref	Spore formation	Confidence
125439		91.219

Murein

@ref	Murein short key	Type
8830	A11.02	A3alpha L-Lys-Gly_5-6

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68371	27613 ChEBI	amygdalin	-	builds acid from	from API 50CH acid
68375	22599 ChEBI	arabinose	-	fermentation	from API ID32STA
68371	18305 ChEBI	arbutin	-	builds acid from	from API 50CH acid
68375	29016 ChEBI	arginine	+	hydrolysis	from API ID32STA
68375	17057 ChEBI	cellobiose	-	fermentation	from API ID32STA
68371	17057 ChEBI	cellobiose	-	builds acid from	from API 50CH acid
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68375	15824 ChEBI	D-fructose	+	fermentation	from API ID32STA
68371	15824 ChEBI	D-fructose	+	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	+	builds acid from	from API 50CH acid
68375	17634 ChEBI	D-glucose	+	fermentation	from API ID32STA
68371	17634 ChEBI	D-glucose	+	builds acid from	from API 50CH acid
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68375	16899 ChEBI	D-mannitol	-	fermentation	from API ID32STA
68371	16899 ChEBI	D-mannitol	-	builds acid from	from API 50CH acid
68375	16024 ChEBI	D-mannose	+	fermentation	from API ID32STA
68371	16024 ChEBI	D-mannose	+	builds acid from	from API 50CH acid
68375	16988 ChEBI	D-ribose	+	fermentation	from API ID32STA
68371	16988 ChEBI	D-ribose	+	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68371	16443 ChEBI	D-tagatose	-	builds acid from	from API 50CH acid
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
68375	4853 ChEBI	esculin	-	hydrolysis	from API ID32STA
68371	4853 ChEBI	esculin	-	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68371	28066 ChEBI	gentiobiose	-	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	-	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68371	30849 ChEBI	L-arabinose	-	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68375	17716 ChEBI	lactose	+	fermentation	from API ID32STA
68375	17306 ChEBI	maltose	-	fermentation	from API ID32STA
68371	17306 ChEBI	maltose	-	builds acid from	from API 50CH acid
68371	6731 ChEBI	melezitose	-	builds acid from	from API 50CH acid
68371	28053 ChEBI	melibiose	-	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
68375	59640 ChEBI	N-acetylglucosamine	+	fermentation	from API ID32STA
68371	59640 ChEBI	N-acetylglucosamine	+	builds acid from	from API 50CH acid
68375	17632 ChEBI	nitrate	+	reduction	from API ID32STA
120021	17632 ChEBI	nitrate	+	reduction
120021	16301 ChEBI	nitrite	+	reduction
68375	18257 ChEBI	ornithine	-	degradation	from API ID32STA
68371	0 ChEBI	Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371	0 ChEBI	Potassium 5-ketogluconate	-	builds acid from	from API 50CH acid
68375	16634 ChEBI	raffinose	-	fermentation	from API ID32STA
68371	16634 ChEBI	raffinose	-	builds acid from	from API 50CH acid
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
68371	17814 ChEBI	salicin	-	builds acid from	from API 50CH acid
68371	28017 ChEBI	starch	-	builds acid from	from API 50CH acid
68375	17992 ChEBI	sucrose	+	fermentation	from API ID32STA
68371	17992 ChEBI	sucrose	+	builds acid from	from API 50CH acid
68371	27082 ChEBI	trehalose	+	builds acid from	from API 50CH acid
68375	27082 ChEBI	trehalose	+	fermentation	from API ID32STA
68375	32528 ChEBI	turanose	-	fermentation	from API ID32STA
68371	32528 ChEBI	turanose	-	builds acid from	from API 50CH acid
68375	16199 ChEBI	urea	-	hydrolysis	from API ID32STA
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Antibiotic resistance

@ref	ChEBI	Group ID	Metabolite	Is sensitive	Sensitivity conc.	Is resistant
120021			0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)
68375	28368	0	novobiocin		1.8 µg		from API ID32STA

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68375	15688 ChEBI	acetoin		from API ID32STA
120021	35581 ChEBI	indole

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test
68375	15688 ChEBI	acetoin	-	from API ID32STA

Enzymes

@ref	Value	Activity	Ec
120021	alcohol dehydrogenase	+	1.1.1.1
68375	alkaline phosphatase	+	3.1.3.1	from API ID32STA
68375	arginine dihydrolase	+	3.5.3.6	from API ID32STA
120021	beta-galactosidase	+	3.2.1.23
68375	beta-galactosidase	-	3.2.1.23	from API ID32STA
68375	beta-glucosidase	-	3.2.1.21	from API ID32STA
68375	beta-glucuronidase	+	3.2.1.31	from API ID32STA
8830	catalase	+	1.11.1.6
120021	catalase	+	1.11.1.6
120021	coagulase	-
8830	cytochrome-c oxidase	-	1.9.3.1
120021	DNase	+
120021	gelatinase	+
68375	L-arginine arylamidase	-		from API ID32STA
120021	lecithinase	-
120021	lysine decarboxylase	-	4.1.1.18
120021	ornithine decarboxylase	-	4.1.1.17
68375	ornithine decarboxylase	-	4.1.1.17	from API ID32STA
120021	oxidase	-
68375	pyrrolidonyl arylamidase	-	3.4.19.3	from API ID32STA
120021	urease	-	3.5.1.5
68375	urease	-	3.5.1.5	from API ID32STA

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
120021	not determinedn.d.	-	-	-	-	+	-	-	-	-	+	+	+	+	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	+/-	-	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

API ID32STA

@ref	URE	ADH (Arg)	ODC	ESC	GLU	FRU	MNE	MAL	LAC	TRE	MAN	RAF	RIB	CEL	Reduction of nitrateNIT	Acetoin production (Voges Proskauer test)VP	beta GAL	L-arginine arylamidaseArgA	PAL	Pyrrolidonyl arylamidasePyrA	NOVO	SAC	NAG	TUR	ARA	beta GUR
8830	-	+	-	-	+	+	+	-	+	+	-	-	+	-	+	-	-	-	+	-	-	+	+	-	-	+
8830	-	+	-	-	+	+	+	-	+	+	-	-	+	-	+	-	-	-	+	-	-	+	+	-	-	+
8830	-	+	-	-	+	+	+	-	+	+	-	-	+	-	+	-	-	-	+	-	-	+	+	-	-	+

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Infection	#Disease	-
#Host	#Mammals	#Suidae (Pig,Swine)
#Host Body-Site	#Organ	#Skin, Nail, Hair

Isolation

@ref	Sample type
8830	pig with exudative epidermitis
67770	Pig with exudative epidermitis
120021	Animal, Pig with exudative epidermitis

Taxonmaps

69479

Global distribution of 16S sequence D83368 (>99% sequence identity) for Staphylococcus from Microbeatlas

Aquatic Samples	1
Soil Samples	1
Animal Samples	72
Plant Samples	0
Total Samples	74

Interaction and safety

Risk assessment

@ref	Pathogenicity animal	Biosafety level	Biosafety level comment
8830		2	Risk group (German classification) According to TRBA 466
120021		1	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	41315_E01 assembly for Staphylococcus hyicus NCTC10350	complete	GCA_900474585	1284.32	2811995276	1284	97.15
66792	ASM81608v1 assembly for Staphylococcus hyicus ATCC 11249	complete	GCA_000816085	1284.6	2645727708	1284	96.75
66792	ASM397047v1 assembly for Staphylococcus hyicus CCUG 6509	scaffold	GCA_003970475	147469.3	8110173636	1284	58.81

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Staphylococcus hyicus strain DSM 20459 16S ribosomal RNA gene, partial sequence	AY688066	464	1284
8830	Staphylococcus hyicus gene for 16S rRNA, partial sequence, strain: ATCC 11249	D83368	1476	1284
124043	Staphylococcus hyicus strain PCM 2192 16S ribosomal RNA gene, partial sequence.	MF678941	1283	1284
124043	Staphylococcus hyicus strain PCM 2192 16S ribosomal RNA gene, partial sequence 16S-23S ribosomal RNA intergenic spacer, complete sequence and 23S ribosomal RNA gene, partial sequence.	MF678885	4422	1284

GC content

@ref	GC-content (mol%)	Method
8830	34.8
8830	32.9
67770	32.9	thermal denaturation, midpoint method (Tm)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: 41315_E01 assembly for Staphylococcus hyicus NCTC10350
BV-BRC: 1284.32

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	facultative anaerobe	90.57	no
125439	gram_stain	BacteriaNetⓘ	positive	62.46	no
125439	motility	BacteriaNetⓘ	no	72.05	no
125439	spore_formation	BacteriaNetⓘ	no	91.22	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Staphylococcus hyicus ATCC 11249
NCBI: GCA_000816085.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	82.96	no
125438	anaerobic	anaerobicⓘ	no	98.38	no
125438	aerobic	aerobicⓘ	yes	53.96	no
125438	spore-forming	spore-formingⓘ	no	68.30	no
125438	thermophilic	thermophileⓘ	no	96.79	yes
125438	flagellated	motile2+ⓘ	no	81.56	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	First Molecular Characterization of Siphoviridae-Like Bacteriophages Infecting Staphylococcus hyicus in a Case of Exudative Epidermitis.	Tetens J, Sprotte S, Thimm G, Wagner N, Brinks E, Neve H, Holzel CS, Franz CMAP.	Front Microbiol	10.3389/fmicb.2021.653501	2021
	Distribution of the putative virulence factor encoding gene sheta in Staphylococcus hyicus strains of various origins.	Kanbar T, Voytenko AV, Alber J, Lammler C, Weiss R, Skvortzov VN.	J Vet Sci	10.4142/jvs.2008.9.3.327	2008
Enzymology	The Non-Lantibiotic Bacteriocin Garvicin Q Targets Man-PTS in a Broad Spectrum of Sensitive Bacterial Genera.	Tymoszewska A, Diep DB, Wirtek P, Aleksandrzak-Piekarczyk T.	Sci Rep	10.1038/s41598-017-09102-7	2017
Pathogenicity	BacSJ-Another Bacteriocin with Distinct Spectrum of Activity that Targets Man-PTS.	Tymoszewska A, Walczak P, Aleksandrzak-Piekarczyk T.	Int J Mol Sci	10.3390/ijms21217860	2020
Phylogeny	Comparative study using various methods for identification of Staphylococcus species in clinical specimens.	Layer F, Ghebremedhin B, Moder KA, Konig W, Konig B.	J Clin Microbiol	10.1128/jcm.00226-06	2006
Enzymology	Complete nucleotide sequence of the lipase gene from Staphylococcus hyicus cloned in Staphylococcus carnosus.	Gotz F, Popp F, Korn E, Schleifer KH.	Nucleic Acids Res	10.1093/nar/13.16.5895	1985
	Detection of Staphylococcus aureus by polymerase chain reaction amplification of the nuc gene.	Brakstad OG, Aasbakk K, Maeland JA.	J Clin Microbiol	10.1128/jcm.30.7.1654-1660.1992	1992
Metabolism	Effects of in vitro and in vivo growth conditions on expression of type 8 capsular polysaccharide by Staphylococcus aureus.	Lee JC, Takeda S, Livolsi PJ, Paoletti LC.	Infect Immun	10.1128/iai.61.5.1853-1858.1993	1993
Metabolism	Relative availability of transferrin-bound iron and cell-derived iron to aerobactin-producing and enterochelin-producing strains of Escherichia coli and to other microorganisms.	Brock JH, Williams PH, Liceaga J, Wooldridge KG.	Infect Immun	10.1128/iai.59.9.3185-3190.1991	1991
	Characterization of cell envelope proteins of Staphylococcus epidermidis cultured in human peritoneal dialysate.	Smith DG, Wilcox MH, Williams P, Finch RG, Denyer SP.	Infect Immun	10.1128/iai.59.2.617-624.1991	1991
	Staphylococci express a receptor for human transferrin: identification of a 42-kilodalton cell wall transferrin-binding protein.	Modun B, Kendall D, Williams P.	Infect Immun	10.1128/iai.62.9.3850-3858.1994	1994
Phylogeny	Draft genome sequences of four Staphylococcus hyicus strains, SC302, SC304, SC306, and SC310, isolated from swine from Eastern Canada.	Gagne-Thivierge C, Vincent AT, Paquet VE, Gauthier M-L, Denicourt M, Lambert M-E, Charette SJ.	Microbiol Resour Announc	10.1128/mra.00626-23	2023
	Role of Staphylococcus agnetis and Staphylococcus hyicus in the Pathogenesis of Buffalo Fly Skin Lesions in Cattle.	Naseem MN, Turni C, Gilbert R, Raza A, Allavena R, McGowan M, Constantinoiu C, Ong CT, Tabor AE, James P.	Microbiol Spectr	10.1128/spectrum.00873-22	2022
	Species identification by MALDI-TOF MS and gap PCR-RFLP of non-aureus Staphylococcus, Mammaliicoccus, and Streptococcus spp. associated with sheep and goat mastitis.	Rosa NM, Penati M, Fusar-Poli S, Addis MF, Tola S.	Vet Res	10.1186/s13567-022-01102-4	2022
Phylogeny	Species Identification and Strain Typing of Staphylococcus agnetis and Staphylococcus hyicus Isolates from Bovine Milk by Use of a Novel Multiplex PCR Assay and Pulsed-Field Gel Electrophoresis.	Adkins PRF, Middleton JR, Calcutt MJ, Stewart GC, Fox LK.	J Clin Microbiol	10.1128/jcm.02239-16	2017
Metabolism	Staphylococcus aureus Genomes Harbor Only MpsAB-Like Bicarbonate Transporter but Not Carbonic Anhydrase as Dissolved Inorganic Carbon Supply System.	Fan SH, Liberini E, Gotz F.	Microbiol Spectr	10.1128/spectrum.00970-21	2021
Pathogenicity	Virulence factors in coagulase-positive staphylococci of veterinary interest other than Staphylococcus aureus.	Gonzalez-Martin M, Corbera JA, Suarez-Bonnet A, Tejedor-Junco MT.	Vet Q	10.1080/01652176.2020.1748253	2020
Enzymology	Occurrence of Methicillin-Resistant Staphylococcus spp. on Brazilian Dairy Farms that Produce Unpasteurized Cheese.	Freitas Ribeiro L, Akira Sato R, de Souza Pollo A, Marques Rossi GA, do Amaral LA.	Toxins (Basel)	10.3390/toxins12120779	2020
Phylogeny	Evolutionary and Functional Analysis of Coagulase Positivity among the Staphylococci.	Pickering AC, Yebra G, Gong X, Goncheva MI, Wee BA, MacFadyen AC, Muehlbauer LF, Alves J, Cartwright RA, Paterson GK, Fitzgerald JR.	mSphere	10.1128/msphere.00381-21	2021
Enzymology	Staphylococcus hyicus bacteremia in a farmer.	Casanova C, Iselin L, von Steiger N, Droz S, Sendi P.	J Clin Microbiol	10.1128/jcm.05645-11	2011
Metabolism	The MpsAB Bicarbonate Transporter Is Superior to Carbonic Anhydrase in Biofilm-Forming Bacteria with Limited CO₂ Diffusion.	Fan SH, Matsuo M, Huang L, Tribelli PM, Gotz F.	Microbiol Spectr	10.1128/spectrum.00305-21	2021
Pathogenicity	Suicin 90-1330 from a nonvirulent strain of Streptococcus suis: a nisin-related lantibiotic active on gram-positive swine pathogens.	LeBel G, Vaillancourt K, Frenette M, Gottschalk M, Grenier D.	Appl Environ Microbiol	10.1128/aem.01055-14	2014
	Application of tuf gene sequence analysis for the identification of species of coagulase-negative staphylococci in clinical samples and evaluation of their antimicrobial resistance pattern.	Khosravi AD, Roointan M, Abbasi Montazeri E, Aslani S, Hashemzadeh M, Taheri Soodejani M.	Infect Drug Resist	10.2147/idr.s172144	2018
	Suicin 3908, a new lantibiotic produced by a strain of Streptococcus suis serotype 2 isolated from a healthy carrier pig.	Vaillancourt K, LeBel G, Frenette M, Gottschalk M, Grenier D.	PLoS One	10.1371/journal.pone.0117245	2015
Metabolism	Production and properties of bacteriocin-like inhibitory substances from the swine pathogen Streptococcus suis serotype 2.	Melancon D, Grenier D.	Appl Environ Microbiol	10.1128/aem.69.8.4482-4488.2003	2003
Pathogenicity	Antimicrobial susceptibility of Staphylococcus hyicus isolated from exudative epidermitis in pigs.	Wegener HC, Watts JL, Salmon SA, Yancey RJ.	J Clin Microbiol	10.1128/jcm.32.3.793-795.1994	1994
Phylogeny	Identification of Staphylococcus species and subspecies by the chaperonin 60 gene identification method and reverse checkerboard hybridization.	Goh SH, Santucci Z, Kloos WE, Faltyn M, George CG, Driedger D, Hemmingsen SM.	J Clin Microbiol	10.1128/jcm.35.12.3116-3121.1997	1997
Enzymology	Evaluation of the Rapid Mastitis Test for identification of Staphylococcus aureus and Streptococcus agalactiae isolated from bovine mammary glands.	Watts JL, Owens WE.	J Clin Microbiol	10.1128/jcm.26.4.672-674.1988	1988
Enzymology	Evaluation of the Staph-Zym system with staphylococci isolated from bovine intramammary infections.	Watts JL, Washburn PJ.	J Clin Microbiol	10.1128/jcm.29.1.59-61.1991	1991
Enzymology	Patterns of antibodies to staphylococcal DNases in dog sera.	Ness E.	J Clin Microbiol	10.1128/jcm.20.4.806-807.1984	1984
	Different staphylococcal species contain various numbers of penicillin-binding proteins ranging from four (Staphylococcus aureus) to only one (Staphylococcus hyicus).	Canepari P, Varaldo PE, Fontana R, Satta G.	J Bacteriol	10.1128/jb.163.2.796-798.1985	1985
Enzymology	Comparison of the API Staph-Ident and DMS Staph Trac micromethods for the identification of coagulase-negative staphylococci.	Giovannetti DI, Barnum DA.	Can J Vet Res		1986
Enzymology	Development of a rapid PCR assay specific for Staphylococcus saprophyticus and application to direct detection from urine samples.	Martineau F, Picard FJ, Menard C, Roy PH, Ouellette M, Bergeron MG.	J Clin Microbiol	10.1128/jcm.38.9.3280-3284.2000	2000
Phylogeny	Development of a PCR assay for identification of staphylococci at genus and species levels.	Martineau F, Picard FJ, Ke D, Paradis S, Roy PH, Ouellette M, Bergeron MG.	J Clin Microbiol	10.1128/jcm.39.7.2541-2547.2001	2001
Enzymology	Differentiation of staphylococci on the basis of nuclease properties.	Gudding R.	J Clin Microbiol	10.1128/jcm.18.5.1098-1101.1983	1983
Phylogeny	Rapid and accurate species-level identification of coagulase-negative staphylococci by using the sodA gene as a target.	Poyart C, Quesne G, Boumaila C, Trieu-Cuot P.	J Clin Microbiol	10.1128/jcm.39.12.4296-4301.2001	2001
Enzymology	Evaluation of the Staph-Ident and STAPHase systems for identification of staphylococci from bovine intramammary infections.	Watts JL, Pankey JW, Nickerson SC.	J Clin Microbiol	10.1128/jcm.20.3.448-452.1984	1984
	Identification of a methicillin-resistant strain of Staphylococcus caprae from a human clinical specimen.	Kanda K, Suzuki E, Hiramatsu K, Oguri T, Miura H, Ezaki T, Yokota T.	Antimicrob Agents Chemother	10.1128/aac.35.1.174	1991
	A method for monitoring antibodies against staphylococcal DNases.	Hoie S, Gudding R.	Acta Vet Scand	10.1186/bf03547565	1990
Phylogeny	Characterization of staphylococci.	Hoover DG, Tatini SR, Maltais JB.	Appl Environ Microbiol	10.1128/aem.46.3.649-660.1983	1983
Enzymology	Identification of veterinary pathogens by use of commercial identification systems and new trends in antimicrobial susceptibility testing of veterinary pathogens.	Watts JL, Yancey RJ.	Clin Microbiol Rev	10.1128/cmr.7.3.346	1994
Enzymology	Microtube coagulase test for detection of coagulase-positive staphylococci.	Goldstein J, Roberts JW.	J Clin Microbiol	10.1128/jcm.15.5.848-851.1982	1982
Phylogeny	Identification of coagulase-negative staphylococci by electrophoretic profile of total proteins and analysis of penicillin-binding proteins.	Pierre J, Gutmann L, Bornet M, Bergogne-Berezin E, Williamson R.	J Clin Microbiol	10.1128/jcm.28.3.443-446.1990	1990
Enzymology	Comparison of the staphylocoagulase activities of Staphylococcus aureus and Staphylococcus intermedius on Chromozym-TH.	Raus J, Love DN.	J Clin Microbiol	10.1128/jcm.28.2.207-210.1990	1990
	Direct testing of blood culture for detection of the serotype 5 and 8 capsular polysaccharides of Staphylococcus aureus.	Boutonnier A, Nato F, Bouvet A, Lebrun L, Audurier A, Mazie JC, Fournier JM.	J Clin Microbiol	10.1128/jcm.27.5.989-993.1989	1989
	Therapeutic Potential of Insect Defensin DLP4 Against Staphylococcus hyicus-Infected Piglet Exudative Epidermitis.	Ma X, Dong Z, Mao R, Tian X, Yang N, Ren W, Hao Y, Shen W, Teng D, Li X, Wang J.	Pharmaceutics	10.3390/pharmaceutics16111350	2024
	The Pharmacodynamics Study of Insect Defensin DLP4 Against Toxigenic Staphylococcus hyicus ACCC 61734 in Vitro and Vivo.	Ma X, Yang N, Mao R, Hao Y, Yan X, Teng D, Wang J.	Front Cell Infect Microbiol	10.3389/fcimb.2021.638598	2021
	Recombinant of the Staphylococcal Bacteriophage Lysin CHAP_k and Its Elimination against Streptococcus agalactiae Biofilms.	Shan Y, Yang N, Teng D, Wang X, Mao R, Hao Y, Ma X, Fan H, Wang J.	Microorganisms	10.3390/microorganisms8020216	2020
	Staphylococcus hyicus virulence in relation to exudative epidermitis in pigs.	Wegener HC, Andresen LO, Bille-Hansen V.	Can J Vet Res		1993
Enzymology	Characterization of Staphylococcus hyicus with the ATB 32 Staph system and with conventional tests.	Lammler C.	J Clin Microbiol	10.1128/jcm.29.6.1221-1224.1991	1991
Metabolism	Characteristic bacteriolytic activities of Staphylococcus hyicus.	Lammler C.	J Clin Microbiol	10.1128/jcm.27.7.1682-1683.1989	1989
Phylogeny	Identification of coagulase-positive Staphylococcus intermedius and Staphylococcus hyicus subsp. hyicus isolates from veterinary clinical specimens.	Phillips WE, Kloos WE.	J Clin Microbiol	10.1128/jcm.14.6.671-673.1981	1981
Metabolism	Biochemical properties of a novel metalloprotease from Staphylococcus hyicus subsp. hyicus involved in extracellular lipase processing.	Ayora S, Lindgren PE, Gotz F.	J Bacteriol	10.1128/jb.176.11.3218-3223.1994	1994
Enzymology	Detection of enterotoxigenic Staphylococcus aureus in dried skimmed milk: use of the polymerase chain reaction for amplification and detection of staphylococcal enterotoxin genes entB and entC1 and the thermonuclease gene nuc.	Wilson IG, Cooper JE, Gilmour A.	Appl Environ Microbiol	10.1128/aem.57.6.1793-1798.1991	1991
	Use of tuf as a target for sequence-based identification of Gram-positive cocci of the genus Enterococcus, Streptococcus, coagulase-negative Staphylococcus, and Lactococcus.	Li X, Xing J, Li B, Wang P, Liu J.	Ann Clin Microbiol Antimicrob	10.1186/1476-0711-11-31	2012
	Draft Genome Sequences of 64 Type Strains of 50 Species and 25 Subspecies of the Genus Staphylococcus Rosenbach 1884.	Cole K, Foster D, Russell JE, Golubchik T, Llewelyn M, Wilson DJ, Crook D, Paul J, Modernising Medical Microbiology Consortium.	Microbiol Resour Announc	10.1128/mra.00062-19	2019
	Erythritol alters the expression of genes related to sugar and arginine metabolisms and suppresses the growth of Staphylococcus hyicus.	Onishi-Sakamoto S, Watanabe K, Fujii T, Yamamoto K, Makida R, Tochio T, Nishifuji K.	Vet Dermatol	10.1111/vde.13364	2025
	Exposure of Buffalo Milkers to Pathogenic Bacteria and Characterization of Isolated Methicillin-Resistant Staphylococcus spp.	Carraturo F, Alterisio MC, Guccione J, Cerullo V, Salamone M, Morelli M, Libralato G, Russo E, d'Angelo R, Ciaramella P, Di Loria A, Guida M.	Int J Environ Res Public Health	10.3390/ijerph19074353	2022
Pathogenicity	Design and Pharmacodynamics of Recombinant Fungus Defensin NZL with Improved Activity against Staphylococcus hyicus In Vitro and In Vivo.	Liu H, Yang N, Teng D, Mao R, Hao Y, Ma X, Wang J	Int J Mol Sci	10.3390/ijms22115435	2021
Pathogenicity	A new high-yielding antimicrobial peptide NZX and its antibacterial activity against Staphylococcus hyicus in vitro/vivo.	Liu H, Yang N, Mao R, Teng D, Hao Y, Wang X, Wang J	Appl Microbiol Biotechnol	10.1007/s00253-019-10313-3	2020
Transcriptome	Sequence Analysis of Staphylococcus hyicus ATCC 11249T, an Etiological Agent of Exudative Epidermitis in Swine, Reveals a Type VII Secretion System Locus and a Novel 116-Kilobase Genomic Island Harboring Toxin-Encoding Genes.	Calcutt MJ, Foecking MF, Hsieh HY, Adkins PR, Stewart GC, Middleton JR	Genome Announc	10.1128/genomeA.01525-14	2015
Transcriptome	An IgG-binding protein A homolog in Staphylococcus hyicus.	Rosander A, Guss B, Pringle M	Vet Microbiol	10.1016/j.vetmic.2010.10.011	2010
Cultivation	Studies on the effect of divalent metal ions on exfoliative toxins from Staphylococcus hyicus: indications of ExhA and ExhB being metalloproteins.	Andresen LO	FEMS Immunol Med Microbiol	10.1111/j.1574-695X.1999.tb01251.x	1999
Phylogeny	Differentiation and distribution of three types of exfoliative toxin produced by Staphylococcus hyicus from pigs with exudative epidermitis.	Andresen LO	FEMS Immunol Med Microbiol	10.1111/j.1574-695X.1998.tb01140.x	1998
Metabolism	Isolation and biological characterization of staphyloferrin B, a compound with siderophore activity from staphylococci.	Haag H, Fiedler HP, Meiwes J, Drechsel H, Jung G, Zahner H	FEMS Microbiol Lett	10.1111/j.1574-6968.1994.tb06626.x	1994
Enzymology	Purification and chemical characterization of staphyloferrin B, a hydrophilic siderophore from staphylococci.	Drechsel H, Freund S, Nicholson G, Haag H, Jung O, Zahner H, Jung G	Biometals	10.1007/BF00205858	1993
Enzymology	Staphyloferrin A: a structurally new siderophore from staphylococci.	Konetschny-Rapp S, Jung G, Meiwes J, Zahner H	Eur J Biochem	10.1111/j.1432-1033.1990.tb19094.x	1990
Phylogeny	Isolation and characterization of staphyloferrin A, a compound with siderophore activity from Staphylococcus hyicus DSM 20459.	Meiwes J, Fiedler HP, Haag H, Zahner H, Konetschny-Rapp S, Jung G	FEMS Microbiol Lett	10.1111/j.1574-6968.1990.tb13863.x	1990
Enzymology	Isolation and characterization of a staphylococcal enzyme bacteriolytic on streptococci.	Muller HP, Blobel H	Zentralbl Bakteriol Mikrobiol Hyg A	10.1016/s0176-6724(87)80123-2	1987
	Chemical composition and structure of cell wall teichoic acids of staphylococci.	Endl J, Seidl HP, Fiedler F, Schleifer KH	Arch Microbiol	10.1007/BF00414483	1983
Phylogeny	Staphylococcus agnetis sp. nov., a coagulase-variable species from bovine subclinical and mild clinical mastitis.	Taponen S, Supre K, Piessens V, Van Coillie E, De Vliegher S, Koort JMK	Int J Syst Evol Microbiol	10.1099/ijs.0.028365-0	2011

References

#8830	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 20459
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#37621	; Curators of the CIP;
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68371	Automatically annotated from API 50CH acid .
#68375	Automatically annotated from API ID32STA .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#120021	Collection of Institut Pasteur ; Curators of the CIP; CIP 81.58
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Staphylococcus hyicus subsp. hyicus (DSM 20459, ATCC 11249, CCM 2368)

Name and taxonomic classification

Morphology

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Culture medium

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Physiology and metabolism

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