Borrelia burgdorferi IRS is a microaerophile, mesophilic prokaryote that was isolated from tick .
microaerophile mesophilic| @ref 20215 |
Last LPSN update
2025-12-16 09:50:19 |
| Domain Pseudomonadati |
| Phylum Spirochaetota |
| Class Spirochaetia |
| Order Spirochaetales |
| Family Borreliaceae |
| Genus Borrelia |
| Species Borrelia burgdorferi |
| Full scientific name Borrelia burgdorferi Johnson et al. 1984 |
| Synonyms (1) |
| BacDive ID | Other strains from Borrelia burgdorferi (3) | Type strain |
|---|---|---|
| 14302 | B. burgdorferi B31, DSM 4680, ATCC 35210, CIP 102532 (type strain) | |
| 136980 | B. burgdorferi CA 8, CIP 109134 | |
| 136981 | B. burgdorferi |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 1678 | BSK-MEDIUM (DSMZ Medium 403) | Medium recipe at MediaDive  | Name: BSK-MEDIUM (DSMZ Medium 403) Composition: Bovine serum albumin 35.0245 g/l Gelatine 9.79706 g/l HEPES buffer 4.19874 g/l Proteose peptone no. 2 3.49895 g/l Glucose 2.09937 g/l Proteose yeastolate 0.69979 g/l Tryptone peptone 0.69979 g/l Na-pyruvate 0.559832 g/l Sodium citrate 0.489853 g/l N-Acetylglucosamine 0.279916 g/l MgCl2 x 6 H2O 0.209937 g/l L-Glutamine 0.069979 g/l Double distilled water CMRL 1066 Rabbit serum |
| @ref | Growth | Type | Temperature (°C) | Range | |
|---|---|---|---|---|---|
| 1678 | positive | growth | 35 | mesophilic |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Use of Tick Cell Lines in Co-Infection Studies with a Preliminary Study of Co-Culture of Borrelia burgdorferi and Anaplasma phagocytophilum. | Zajac V, Bell-Sakyi L, Wojcik-Fatla A. | Pathogens | 10.3390/pathogens14010078 | 2025 |  | |
| Development of a Syndromic Molecular Diagnostic Assay for Tick-Borne Pathogens Using Barcoded Magnetic Bead Technology. | Mohseni N, Chang M, Garcia K, Weakley M, Do T, Mir S. | Microbiol Spectr | 10.1128/spectrum.04395-22 | 2023 | | |
| Metabolism | Production of reactive oxygen species and expression of inducible nitric oxide synthase in rat isolated Kupffer cells stimulated by Leptospira interrogans and Borrelia burgdorferi. | Marangoni A, Accardo S, Aldini R, Guardigli M, Cavrini F, Sambri V, Montagnani M, Roda A, Cevenini R. | World J Gastroenterol | 10.3748/wjg.v12.i19.3077 | 2006 | |
| Uptake and killing of Leptospira interrogans and Borrelia burgdorferi, spirochetes pathogenic to humans, by reticuloendothelial cells in perfused rat liver. | Marangoni A, Aldini R, Sambri V, Montagnani M, Ballardini G, Storni E, Cevenini R. | Infect Immun | 10.1128/iai.68.9.5408-5411.2000 | 2000 | | |
| Enzymology | Detection of the Lyme disease bacterium, Borrelia burgdorferi, by using the polymerase chain reaction and a nonradioisotopic gene probe. | Wise DJ, Weaver TL. | J Clin Microbiol | 10.1128/jcm.29.7.1523-1526.1991 | 1991 | |
| Functional characterization of two defensin isoforms of the hard tick Ixodes ricinus. | Chrudimska T, Slaninova J, Rudenko N, Ruzek D, Grubhoffer L. | Parasit Vectors | 10.1186/1756-3305-4-63 | 2011 | | |
| Identification of related DNA sequences in Borrelia burgdorferi and two strains of Leptospira interrogans by using polymerase chain reaction. | Kron MA, Gupta A, Mackenzie CD. | J Clin Microbiol | 10.1128/jcm.29.10.2338-2340.1991 | 1991 | | |
| Uptake and killing of Lyme disease and relapsing fever borreliae in the perfused rat liver and by isolated Kupffer cells. | Sambri V, Aldini R, Massaria F, Montagnani M, Casanova S, Cevenini R. | Infect Immun | 10.1128/iai.64.5.1858-1861.1996 | 1996 | | |
| Pathogenicity | Ixodes ricinus salivary serpin IRS-2 affects Th17 differentiation via inhibition of the interleukin-6/STAT-3 signaling pathway. | Palenikova J, Lieskovska J, Langhansova H, Kotsyfakis M, Chmelar J, Kopecky J. | Infect Immun | 10.1128/iai.03065-14 | 2015 | |
| Phylogeny | Heterogeneity in immunoblot patterns obtained by using four strains of Borrelia burgdorferi and sera from naturally exposed dogs. | Greene RT, Walker RL, Burgess EC, Levine JF. | J Clin Microbiol | 10.1128/jcm.26.11.2287-2291.1988 | 1988 | |
| Further characterization of a potent immunogen and the chromosomal gene encoding it in the Lyme disease agent, Borrelia burgdorferi. | Perng GC, LeFebvre RB, Johnson RC. | Infect Immun | 10.1128/iai.59.6.2070-2074.1991 | 1991 | | |
| Enzymology | Detection of Borrelia burgdorferi-specific DNA in urine specimens from patients with erythema migrans before and after antibiotic therapy. | Schmidt B, Muellegger RR, Stockenhuber C, Soyer HP, Hoedl S, Luger A, Kerl H. | J Clin Microbiol | 10.1128/jcm.34.6.1359-1363.1996 | 1996 | |
| Polymerase chain reaction primers and probes derived from flagellin gene sequences for specific detection of the agents of Lyme disease and North American relapsing fever. | Picken RN. | J Clin Microbiol | 10.1128/jcm.30.1.99-114.1992 | 1992 | | |
| Enzymology | Detection of Borrelia burgdorferi using the polymerase chain reaction. | Malloy DC, Nauman RK, Paxton H. | J Clin Microbiol | 10.1128/jcm.28.6.1089-1093.1990 | 1990 | |
| Infection of Syrian hamsters with Lyme disease spirochetes. | Johnson RC, Marek N, Kodner C. | J Clin Microbiol | 10.1128/jcm.20.6.1099-1101.1984 | 1984 | | |
| Characterization of Borrelia coriaceae antigens with monoclonal antibodies. | Blanchard-Channell M, Stott JL. | Infect Immun | 10.1128/iai.59.8.2790-2798.1991 | 1991 | | |
| Phylogeny | A novel alpha-Proteobacterium resides in the mitochondria of ovarian cells of the tick Ixodes ricinus. | Beninati T, Lo N, Sacchi L, Genchi C, Noda H, Bandi C. | Appl Environ Microbiol | 10.1128/aem.70.5.2596-2602.2004 | 2004 | |
| Phylogeny | DNA characterization of the spirochete that causes Lyme disease. | Schmid GP, Steigerwalt AG, Johnson SE, Barbour AG, Steere AC, Robinson IM, Brenner DJ. | J Clin Microbiol | 10.1128/jcm.20.2.155-158.1984 | 1984 | |
| Seroprotective groups among isolates of Borrelia burgdorferi. | Lovrich SD, Callister SM, Lim LC, Schell RF | Infect Immun | 10.1128/iai.61.10.4367-4374.1993 | 1993 | | |
| Pathogenicity | Antibiotics and increased temperature against Borrelia burgdorferi in vitro. | Reisinger E, Wendelin I, Gasser R, Halwachs G, Wilders-Truschnig M, Krejs G | Scand J Infect Dis | 10.3109/00365549609049067 | 1996 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive14303.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
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