Prevotella histicola (DSM 19854, CCUG 55407, JCM 15637)

Name: Prevotella histicola (DSM 19854, CCUG 55407, JCM 15637)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 12560

Type strain

Strain Designation T05-04

Culture col. no. DSM 19854 CCUG 55407 JCM 15637 T05-04

NCBI tax ID(s) 1236504 470565

Special Collections DSMZ CCUG JCM Literature strains

History <- J. Downes; T05-04 {2008} <- S. J. Hooper CCUG 55407 <-- J. Downes T05-04 <-- S. J. Hooper.

Links

Prevotella histicola T05-04 is an anaerobe, mesophilic, Gram-negative prokaryote that was isolated from human oral squamous cell carcinoma tissue.

Gram-negative rod-shaped anaerobe mesophilic genome sequence 16S sequence

Name and taxonomic classification

SI-ID 396876

JCM 15637,DSM 19854,CCUG 55407

@ref 20215

Last LPSN update 2025-12-16 09:49:52

Domain Pseudomonadati

Phylum Bacteroidota

Class Bacteroidia

Order Bacteroidales

Family Prevotellaceae

Genus Prevotella

Species Prevotella histicola

Full scientific name Prevotella histicola Downes et al. 2008

BacDive ID	Other strains from **Prevotella histicola** (2)	Type strain
12561	P. histicola strain 8400706, DSM 21553
24341	P. histicola CD3:32, DSM 26979, CCUG 60372

Morphology

Cell morphology

@ref	Gram stain	Cell length	Cell width	Cell shape	Confidence
32539	negative	0.8-3 µm	0.7 µm	rod-shaped
125438	negative				94.234
125439	negative				99.5

Colony morphology

@ref	Incubation period
8356	2-3 days
60573	2 days

Pigmentation

32539

Productionyes

Culture and growth conditions

Culture medium

@ref	Name	Growth	Medium link	Composition
8356	COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)		Medium recipe at MediaDive	Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
8356	PYG MEDIUM (MODIFIED) (DSMZ Medium 104)		Medium recipe at MediaDive	Name: PYG MEDIUM (modified) (DSMZ Medium 104) Composition: Yeast extract 10.0 g/l Peptone 5.0 g/l Trypticase peptone 5.0 g/l Beef extract 5.0 g/l Glucose 5.0 g/l L-Cysteine HCl x H2O 0.5 g/l NaHCO3 0.4 g/l NaCl 0.08 g/l K2HPO4 0.04 g/l KH2PO4 0.04 g/l MgSO4 x 7 H2O 0.02 g/l CaCl2 x 2 H2O 0.01 g/l Hemin 0.005 g/l Ethanol 0.0038 g/l Resazurin 0.001 g/l Tween 80 Vitamin K1 NaOH Distilled water

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
8356	positive	growth	37	mesophilic
32539	positive	growth	37	mesophilic
32539	positive	optimum	37	mesophilic
60573	positive	growth	37	mesophilic
67770	positive	growth	37	mesophilic

Culture pH

@ref	Ability	Type	PH
32539	positive	optimum	7
32539	positive	growth	7

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance
8356	anaerobe
32539	anaerobe
60573	anaerobe

Spore formation

@ref	Spore formation	Confidence
32539
125438		93.475
125439		99.6

Observation

32539

Observationaggregates in chains

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
32539	22599 ChEBI	arabinose	+	carbon source
68380	29016 ChEBI	arginine	-	hydrolysis	from API rID32A
32539	17057 ChEBI	cellobiose	+	carbon source
68380	29985 ChEBI	L-glutamate	-	degradation	from API rID32A
32539	17716 ChEBI	lactose	+	carbon source
32539	37684 ChEBI	mannose	+	carbon source
68380	17632 ChEBI	nitrate	-	reduction	from API rID32A
32539	16634 ChEBI	raffinose	+	carbon source
32539	17814 ChEBI	salicin	+	carbon source
32539	17992 ChEBI	sucrose	+	carbon source
68380	27897 ChEBI	tryptophan	-	energy source	from API rID32A
68380	16199 ChEBI	urea	-	hydrolysis	from API rID32A

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68380	35581 ChEBI	indole		from API rID32A

Metabolite tests

@ref	Chebi-ID	Metabolite	Indole test
68380	35581 ChEBI	indole	-	from API rID32A

Enzymes

@ref	Value	Activity	Ec
68380	alanine arylamidase	+	3.4.11.2	from API rID32A
68380	alkaline phosphatase	+	3.1.3.1	from API rID32A
68380	alpha-arabinosidase	-	3.2.1.55	from API rID32A
68380	alpha-fucosidase	+	3.2.1.51	from API rID32A
68380	alpha-glucosidase	+	3.2.1.20	from API rID32A
68380	arginine dihydrolase	-	3.5.3.6	from API rID32A
68380	beta-galactosidase	+	3.2.1.23	from API rID32A
68380	beta-Galactosidase 6-phosphate	+		from API rID32A
68380	beta-glucosidase	-	3.2.1.21	from API rID32A
68380	beta-glucuronidase	-	3.2.1.31	from API rID32A
68380	glutamate decarboxylase	-	4.1.1.15	from API rID32A
68380	glycin arylamidase	-		from API rID32A
68380	histidine arylamidase	-		from API rID32A
68380	L-arginine arylamidase	+		from API rID32A
68380	leucine arylamidase	-	3.4.11.1	from API rID32A
68380	leucyl glycin arylamidase	+	3.4.11.1	from API rID32A
68380	N-acetyl-beta-glucosaminidase	+	3.2.1.52	from API rID32A
68380	phenylalanine arylamidase	-		from API rID32A
68380	proline-arylamidase	-	3.4.11.5	from API rID32A
68380	pyrrolidonyl arylamidase	-	3.4.19.3	from API rID32A
68380	serine arylamidase	-		from API rID32A
68380	tryptophan deaminase	-	4.1.99.1	from API rID32A
68380	tyrosine arylamidase	-		from API rID32A
68380	urease	-	3.5.1.5	from API rID32A

API rID32A

@ref	URE	ADH (Arg)	alpha GAL	beta GAL	beta-Galactosidase 6-phosphatebeta GP	alpha GLU	beta GLU	alpha ARA	beta GUR	beta-N-Acetyl-beta-glucosaminidasebeta NAG	MNE	RAF	GDC	alpha FUC	Reduction of nitrateNIT	IND	PAL	L-arginine arylamidaseArgA	ProA	LGA	Phenylalanine arylamidasePheA	Leucine arylamidaseLeuA	PyrA	Tyrosine arylamidaseTyrA	Alanine arylamidaseAlaA	Glycin arylamidaseGlyA	Histidine arylamidaseHisA	Glutamyl-glutamate arylamidaseGGA	Serine arylamidaseSerA
8356	-	-	+/-	+	+	+	-	-	-	+	-	-	-	+	-	-	+	+	-	+	-	-	-	-	+	-	-	+/-	-
8356	-	-	+	+	+	+	-	-	-	+	+	+	-	+	-	-	+	+	-	+	-	-	-	-	+	-	-	+	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2
#Host	#Human
#Host Body-Site	-

Isolation

@ref	Sample type	Sampling date	Geographic location	Country	Country ISO 3 Code	Continent
8356	human oral squamous cell carcinoma tissue			United Kingdom	GBR	Europe
60573	Human oral tissue,squamous cell carcinoma	2004	Cardiff	United Kingdom	GBR	Europe
67770	Human oral cavity

Taxonmaps

69479

Global distribution of 16S sequence AB547685 (>99% sequence identity) for Prevotella histicola subclade from Microbeatlas

Aquatic Samples	1647
Soil Samples	1242
Animal Samples	80804
Plant Samples	518
Total Samples	84211

Interaction and safety

Risk assessment

@ref	Pathogenicity human	Biosafety level	Biosafety level comment
8356	yes, in single cases	1	Risk group (German classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
124043	ASM4779633v1 assembly for Prevotella histicola T05-04	complete	GCA_047796335			470565	59.68
66792	04_NF40_HMP2132v01 assembly for Prevotella histicola JCM 15637 = DNF00424	contig	GCA_000759075		2602041664	1236504	57.29
67770	ASM61392v1 assembly for Prevotella histicola JCM 15637 = DNF00424	contig	GCA_000613925	1236504.5	2585427900	1236504	35.87

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
8356	Prevotella histicola strain T05-04 16S ribosomal RNA gene, partial sequence	EU126661	1453		470565
67770	Prevotella histicola gene for 16S ribosomal RNA, partial sequence, strain: JCM 15637	AB547685	1480		470565

GC content

@ref	GC-content (mol%)	Method
8356	43	high performance liquid chromatography (HPLC)
32539	43
8356	41.2	sequence analysis

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Prevotella histicola JCM 15637 = DNF00424
NCBI: GCA_000759075

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	anaerobe	87.20	no
125439	gram_stain	BacteriaNetⓘ	negative	99.50	no
125439	motility	BacteriaNetⓘ	no	64.70	no
125439	spore_formation	BacteriaNetⓘ	no	99.60	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Prevotella histicola JCM 15637 = DNF00424
PATRIC: 1236504.5

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	94.23	yes
125438	anaerobic	anaerobicⓘ	yes	88.23	yes
125438	spore-forming	spore-formingⓘ	no	93.48	yes
125438	aerobic	aerobicⓘ	no	95.84	yes
125438	thermophilic	thermophileⓘ	no	94.31	yes
125438	flagellated	motile2+ⓘ	no	88.50	yes

Literature

Topic	Title	Authors	Journal	DOI	Year
Genetics	Complete genome sequence of Prevotella histicola T05-04.	Spurgeon K, Erb-Downward JR, Huffnagle GB, Kozik AJ.	Microbiol Resour Announc	10.1128/mra.00144-25	2025
	Metatranscriptomic analysis shows functional alterations in subgingival biofilm in young smokers with periodontitis: a pilot study.	Casarin RCV, Silva RVCD, Paz HES, Stolf CS, Carvalho LM, Noronha MF, Sallum AW, Monteiro MF.	J Appl Oral Sci	10.1590/1678-7757-2024-0031	2024
	Alcohol-Derived Acetaldehyde Exposure in the Oral Cavity.	Stornetta A, Guidolin V, Balbo S.	Cancers (Basel)	10.3390/cancers10010020	2018
Metabolism	Prevotella histicola Protects From Arthritis by Expansion of Allobaculum and Augmenting Butyrate Production in Humanized Mice.	Balakrishnan B, Luckey D, Bodhke R, Chen J, Marietta E, Jeraldo P, Murray J, Taneja V	Front Immunol	10.3389/fimmu.2021.609644	2021
Phylogeny	Prevotella jejuni sp. nov., isolated from the small intestine of a child with coeliac disease.	Hedberg ME, Israelsson A, Moore ERB, Svensson-Stadler L, Wai SN, Pietz G, Sandstrom O, Hernell O, Hammarstrom ML, Hammarstrom S	Int J Syst Evol Microbiol	10.1099/ijs.0.052647-0	2013
Phylogeny	Prevotella histicola sp. nov., isolated from the human oral cavity.	Downes J, Hooper SJ, Wilson MJ, Wade WG	Int J Syst Evol Microbiol	10.1099/ijs.0.65656-0	2008

References

#8356	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 19854
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#28757	IJSEM 1788 2008 ( DOI 10.1099/ijs.0.65656-0 , PubMed 18676457 )
#32539	Barberan A, Caceres Velazquez H, Jones S, Fierer N.: Hiding in Plain Sight: Mining Bacterial Species Records for Phenotypic Trait Information. mSphere 2: 2017 ( DOI 10.1128/mSphere.00237-17 , PubMed 28776041 ) - originally annotated from #28757
#60573	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 55407
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68380	Automatically annotated from API rID32A .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Prevotella histicola (DSM 19854, CCUG 55407, JCM 15637)

Name and taxonomic classification

Morphology

Cell morphology

Colony morphology

Pigmentation

Culture and growth conditions

Culture medium

Culture temp

Culture pH

Physiology and metabolism

Oxygen tolerance

Spore formation

Observation

Metabolite utilization

Metabolite production

Metabolite tests

Enzymes

API rID32A

Isolation, sampling and environmental information

Isolation source categories

Isolation

Taxonmaps

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_047796335

16S sequences

GC content

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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