Haemophilus pleuropneumoniae (DSM 13472, ATCC 27088, CCM 5869)

Name: Haemophilus pleuropneumoniae (DSM 13472, ATCC 27088, CCM 5869)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 11672

Type strain

Strain Designation 4074

Culture col. no. DSM 13472 ATCC 27088 CCM 5869 Shope 4074 CIP 100916 2 more

NCBI tax ID(s) 715

Special Collections DSMZ CCUG CIP

History <- ATCC; <- J. Nicolet; Shope 4074 (Haemophilus parahaemolyticus) <- J. Callis; <- R. E. Shope; CIP <- 1984, ATCC <- J. Nicolet, Haemophilus parahaemolyticus: strain 4074 <- J. Callis <- R. Shope: strain 4074

Links

Haemophilus pleuropneumoniae 4074 is a microaerophile, mesophilic, Gram-negative animal pathogen that was isolated from lung of swine.

Gram-negative oval-shaped microaerophile mesophilic animal pathogen genome sequence 16S sequence

Name and taxonomic classification

SI-ID 38804

ATCC 27088,CCM 5869,CCUG 12837,CIP 100916,CCUG 41656,DSM 13472,CCUG 43096,NCTC 12370

@ref 20215

Last LPSN update 2026-02-09 11:20:37

Domain Bacteria

Phylum Pseudomonadota

Class Gammaproteobacteria

Order Pasteurellales

Family Pasteurellaceae

Genus Haemophilus

Species Haemophilus pleuropneumoniae

Full scientific name Haemophilus pleuropneumoniae corrig. Shope 1964 (Approved Lists 1980)

Synonyms (2)

Hemophilus pleuropneumoniae
Actinobacillus pleuropneumoniae

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Confidence
121870	negative	oval-shaped
125438			92.821
125438	negative		98

Colony morphology

@ref	Type of hemolysis	Incubation period
5054	gamma	1-2 days
121870

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
5054	HAEMOPHILUS MEDIUM (DSMZ Medium 804)	Medium recipe at MediaDive	Name: HAEMOPHILUS MEDIUM (DSMZ Medium 804) Composition: Mueller-Hinton broth 21.0 g/l Yeast extract 5.0 g/l Distilled water
39724	MEDIUM 10 - Chocolate medium for Actinobacillus pleuropneumoniae, Capnocytophaga cynodegmi, Haemophilus and Neisseria		Distilled water make up to (1000.000 ml);Columbia agar (39.000 g);Horseblood (100.000 ml);PolyVitex mischung (10.000 ml)
121870	CIP Medium 10	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
5054	positive	growth	37	mesophilic
39724	positive	growth	37	mesophilic
121870	positive	growth	37	mesophilic

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
5054	microaerophile
125439	microaerophile	93.4

Spore formation

@ref	Spore formation	Confidence
125439		92.5

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68371	27613 ChEBI	amygdalin	-	builds acid from	from API 50CH acid
68371	18305 ChEBI	arbutin	+	builds acid from	from API 50CH acid
68371	17057 ChEBI	cellobiose	+	builds acid from	from API 50CH acid
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68377	15824 ChEBI	D-fructose	+	builds acid from	from API NH
68371	15824 ChEBI	D-fructose	-	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	+	builds acid from	from API 50CH acid
68377	17634 ChEBI	D-glucose	+	builds acid from	from API NH
68371	17634 ChEBI	D-glucose	-	builds acid from	from API 50CH acid
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68371	16899 ChEBI	D-mannitol	-	builds acid from	from API 50CH acid
68371	16024 ChEBI	D-mannose	-	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68371	16443 ChEBI	D-tagatose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68371	28066 ChEBI	gentiobiose	-	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	-	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68371	30849 ChEBI	L-arabinose	+	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68371	17716 ChEBI	lactose	-	builds acid from	from API 50CH acid
68377	17306 ChEBI	maltose	+	builds acid from	from API NH
68371	17306 ChEBI	maltose	-	builds acid from	from API 50CH acid
68371	6731 ChEBI	melezitose	-	builds acid from	from API 50CH acid
68371	28053 ChEBI	melibiose	-	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
68371	59640 ChEBI	N-acetylglucosamine	+	builds acid from	from API 50CH acid
121870	17632 ChEBI	nitrate	+	reduction
121870	16301 ChEBI	nitrite	-	reduction
68377	18257 ChEBI	ornithine	-	degradation	from API NH
68371		Potassium 2-ketogluconate	+	builds acid from	from API 50CH acid
68371		Potassium 5-ketogluconate	+	builds acid from	from API 50CH acid
68371	16634 ChEBI	raffinose	-	builds acid from	from API 50CH acid
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
68371	17814 ChEBI	salicin	-	builds acid from	from API 50CH acid
121870	132112 ChEBI	sodium thiosulfate	-	builds gas from
68371	28017 ChEBI	starch	-	builds acid from	from API 50CH acid
68371	17992 ChEBI	sucrose	-	builds acid from	from API 50CH acid
68377	17992 ChEBI	sucrose	+	builds acid from	from API NH
68371	27082 ChEBI	trehalose	-	builds acid from	from API 50CH acid
68377	27897 ChEBI	tryptophan	-	energy source	from API NH
68371	32528 ChEBI	turanose	-	builds acid from	from API 50CH acid
68377	16199 ChEBI	urea	+	hydrolysis	from API NH
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Antibiotic resistance

@ref	Metabolite	Is sensitive	Is resistant
121870	0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68377	35581 ChEBI	indole		from API NH
121870	35581 ChEBI	indole

Metabolite tests

@ref	Chebi-ID	Metabolite	Indole test	Voges-proskauer-test	Methylred-test
121870	15688 ChEBI	acetoin		-
121870	17234 ChEBI	glucose			-
68377	35581 ChEBI	indole	-			from API NH

Enzymes

@ref	Value	Activity	Ec
121870	alcohol dehydrogenase	-	1.1.1.1
68377	alkaline phosphatase	+	3.1.3.1	from API NH
121870	beta-galactosidase	+	3.2.1.23
68377	beta-galactosidase	+	3.2.1.23	from API NH
68377	beta-lactamase	-	3.5.2.6	from API NH
5054	catalase	-	1.11.1.6
121870	catalase	+	1.11.1.6
5054	cytochrome-c oxidase	+	1.9.3.1
68377	gamma-glutamyltransferase	-	2.3.2.2	from API NH
121870	gelatinase	-
68377	lipase	-		from API NH
121870	lysine decarboxylase	-	4.1.1.18
121870	ornithine decarboxylase	-	4.1.1.17
68377	ornithine decarboxylase	-	4.1.1.17	from API NH
121870	oxidase	+
68377	proline-arylamidase	-	3.4.11.5	from API NH
68377	tryptophan deaminase	-	4.1.99.1	from API NH
121870	urease	+	3.5.1.5
68377	urease	+	3.5.1.5	from API NH

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
121870	not determinedn.d.	-	-	-	+	+/-	+/-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	+	-	+	+/-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	+

API NH

@ref	PEN	GLU	FRU	MAL	SAC	ODC	URE	LIP	PAL	beta GAL	ProA	GGT	IND
5054	-	+	+	+	+	-	+	-	+	+	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Host	#Mammals	#Suidae (Pig,Swine)
#Host Body-Site	#Oral cavity and airways	#Lung

Isolation

@ref	Sample type	Country	Country ISO 3 Code	Continent
5054	lung of swine	Argentina	ARG	Middle and South America
121870	Animal, Pig, lung	Argentina	ARG	Middle and South America

Taxonmaps

69479

Global distribution of 16S sequence D30030 (>99% sequence identity) for Actinobacillus from Microbeatlas

Aquatic Samples	203
Soil Samples	221
Animal Samples	5580
Plant Samples	19
Total Samples	6023

Interaction and safety

Risk assessment

@ref	Pathogenicity animal	Biosafety level	Biosafety level comment
5054		2	Risk group (German classification) According to TRBA 466
121870		1	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM329038v1 assembly for Actinobacillus pleuropneumoniae S4074	complete	GCA_003290385	715.77	2847071526	715	99.49
124043	ASM4243352v1 assembly for Actinobacillus pleuropneumoniae CCM 5869	scaffold	GCA_042433525			715	70.68

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20218	Actinobacillus pleuropneumoniae gene for 16S rRNA	D30030	1743		715
5054	Actinobacillus pleuropneumoniae strain ATCC 27088 16S ribosomal RNA gene, partial sequence	M75074	1478		715

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Actinobacillus pleuropneumoniae strain S4074
PATRIC: 715.77

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	92.50	no
125439	motility	BacteriaNetⓘ	no	68.90	no
125439	gram_stain	BacteriaNetⓘ	negative	65.80	no
125439	oxygen_tolerance	BacteriaNetⓘ	microaerophile	93.40	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Actinobacillus pleuropneumoniae strain S4074
PATRIC: 715.77

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	98.00	no
125438	anaerobic	anaerobicⓘ	no	94.81	yes
125438	spore-forming	spore-formingⓘ	no	89.52	no
125438	aerobic	aerobicⓘ	no	80.14	yes
125438	thermophilic	thermophileⓘ	no	98.00	yes
125438	flagellated	motile2+ⓘ	no	92.82	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Efficiency of different air filter types for pig facilities at laboratory scale.	Wenke C, Pospiech J, Reutter T, Truyen U, Speck S.	PLoS One	10.1371/journal.pone.0186558	2017
	Impact of UVC-sustained recirculating air filtration on airborne bacteria and dust in a pig facility.	Eisenloffel L, Reutter T, Horn M, Schlegel S, Truyen U, Speck S.	PLoS One	10.1371/journal.pone.0225047	2019
Proteome	Transcriptomic and proteomic profiling of Actinobacillus pleuropneumoniae responses to iron starvation.	Cui Y, Chen J, Feng X, Guo F, Shao Y, Xu F.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1669654	2025
Pathogenicity	Novel Experimental Mouse Model to Study the Pathogenesis and Therapy of Actinobacillus pleuropneumoniae Infection.	Bui DT, Lee YS, Kuo TF, Chen ZW, Yang WC.	Pathogens	10.3390/pathogens13050412	2024
	Development of a novel high resolution melting assay for identification and differentiation of all known 19 serovars of Actinobacillus pleuropneumoniae.	Scherrer S, Peterhans S, Neupert C, Rademacher F, Bartolomei G, Sidler X, Stephan R.	Microbiologyopen	10.1002/mbo3.1272	2022
Phylogeny	In silico-derived Actinobacillus equuli-specific DNA markers and development of associated PCR assays.	Songsungthong W, Pornthanakasem W, Leartsakulpanich U, Srijuntongsiri G.	J Vet Diagn Invest	10.1177/10406387251382186	2025
	Optimizing tylosin dosage for co-infection of Actinobacillus pleuropneumoniae and Pasteurella multocida in pigs using pharmacokinetic/pharmacodynamic modeling.	Lee EB, Abbas MA, Park J, Tassew DD, Park SC.	Front Pharmacol	10.3389/fphar.2023.1258403	2023
	Detection of Actinobacillus Pleuropneumoniae ApxIV Toxin Antibody in Serum and Oral Fluid Specimens from Pigs Inoculated Under Experimental Conditions.	Gonzalez W, Gimenez-Lirola LG, Holmes A, Lizano S, Goodell C, Poonsuk K, Sitthicharoenchai P, Sun Y, Zimmerman J.	J Vet Res	10.1515/jvetres-2017-0021	2017
Enzymology	Optimized real-time fluorescence PCR assay for the detection of porcine Circovirus type 3 (PCV3).	Yuan L, Liu Y, Chen Y, Gu X, Dong H, Zhang S, Han T, Zhou Z, Song X, Wang C.	BMC Vet Res	10.1186/s12917-020-02435-y	2020
Phylogeny	Novel multiplex TaqMan assay for differentiation of the four major pathogenic Brachyspira species in swine.	Scherrer S, Stephan R.	Microbiologyopen	10.1002/mbo3.1169	2021
	A Novel Real-Time PCR Assay for the Rapid Detection of Virulent Streptococcus equi Subspecies zooepidemicus-An Emerging Pathogen of Swine.	Kuchipudi SV, Surendran Nair M, Yon M, Gontu A, Nissly RH, Barry R, Greenawalt D, Pierre T, Li L, Thirumalapura N, Tewari D, Jayarao B.	Front Vet Sci	10.3389/fvets.2021.604675	2021
Metabolism	The RNA chaperone Hfq promotes fitness of Actinobacillus pleuropneumoniae during porcine pleuropneumonia.	Subashchandrabose S, Leveque RM, Kirkwood RN, Kiupel M, Mulks MH.	Infect Immun	10.1128/iai.00392-13	2013
	Comparison of four lung scoring systems for the assessment of the pathological outcomes derived from Actinobacillus pleuropneumoniae experimental infections.	Sibila M, Aragon V, Fraile L, Segales J.	BMC Vet Res	10.1186/1746-6148-10-165	2014
Phylogeny	Clear distinction between Burkholderia mallei and Burkholderia pseudomallei using fluorescent motB primers.	Schmoock G, Elschner M, Sprague LD.	Acta Vet Scand	10.1186/s13028-015-0104-4	2015
Metabolism	Levels of nicotinamide adenine dinucleotide in extracellular body fluids of pigs may be growth-limiting for Actinobacillus pleuropneumoniae and Haemophilus parasuis.	O'Reilly T, Niven DF.	Can J Vet Res		2003
Phylogeny	Isolation of an atypical strain of Actinobacillus pleuropneumoniae serotype 1 with a truncated lipopolysaccharide outer core and no O-antigen.	Jacques M, Labrie J, St Michael F, Cox AD, Paradis MA, Dick CP, Klopfenstein C, Broes A, Fittipaldi N, Gottschalk M.	J Clin Microbiol	10.1128/jcm.43.7.3522-3525.2005	2005
	Proteomic and immunoproteomic characterization of a DIVA subunit vaccine against Actinobacillus pleuropneumoniae.	Buettner FF, Konze SA, Maas A, Gerlach GF.	Proteome Sci	10.1186/1477-5956-9-23	2011
	Comparison of Haemophilus parasuis reference strains and field isolates by using random amplified polymorphic DNA and protein profiles.	Zehr ES, Lavrov DV, Tabatabai LB.	BMC Microbiol	10.1186/1471-2180-12-108	2012
Metabolism	Branched-chain amino acids are required for the survival and virulence of Actinobacillus pleuropneumoniae in swine.	Subashchandrabose S, LeVeque RM, Wagner TK, Kirkwood RN, Kiupel M, Mulks MH.	Infect Immun	10.1128/iai.00671-09	2009
	Novel real-time PCR detection assay for Brucella suis.	Hansel C, Mertens K, Elschner MC, Melzer F.	Vet Rec Open	10.1136/vetreco-2014-000084	2015
	Identification of the Actinobacillus pleuropneumoniae leucine-responsive regulatory protein and its involvement in the regulation of in vivo-induced genes.	Wagner TK, Mulks MH.	Infect Immun	10.1128/iai.00120-06	2007
	Molecular cloning and sequencing of the aroA gene from Actinobacillus pleuropneumoniae and its use in a PCR assay for rapid identification.	Hernanz Moral C, Cascon Soriano A, Sanchez Salazar M, Yugueros Marcos J, Suarez Ramos S, Naharro Carrasco G.	J Clin Microbiol	10.1128/jcm.37.5.1575-1578.1999	1999
Enzymology	DNA microarray-based detection of Coxiella burnetii, the causative agent of Q fever.	Schmoock G, Ehricht R, Sprague LD.	Acta Vet Scand	10.1186/1751-0147-56-27	2014
Metabolism	Secreted proteases from Actinobacillus pleuropneumoniae serotype 1 degrade porcine gelatin, hemoglobin and immunoglobulin A.	Negrete-Abascal E, Tenorio VR, Serrano JJ, Garcia C, de la Garza M.	Can J Vet Res		1994
	Identification of dimethyl sulfoxide reductase in Actinobacillus pleuropneumoniae and its role in infection.	Baltes N, Hennig-Pauka I, Jacobsen I, Gruber AD, Gerlach GF.	Infect Immun	10.1128/iai.71.12.6784-6792.2003	2003
	Association of Actinobacillus pleuropneumoniae capsular polysaccharide with virulence in pigs.	Bandara AB, Lawrence ML, Veit HP, Inzana TJ.	Infect Immun	10.1128/iai.71.6.3320-3328.2003	2003
Enzymology	Evaluation of the RapID NH system for identification of Haemophilus somnus, Pasteurella multocida, Pasteurella haemolytica, and Actinobacillus pleuropneumoniae isolated from cattle and pigs with respiratory disease.	Salmon SA, Watts JL, Yancey RJ.	J Clin Microbiol	10.1128/jcm.31.5.1362-1363.1993	1993
Enzymology	Enzymes involved in anaerobic respiration appear to play a role in Actinobacillus pleuropneumoniae virulence.	Jacobsen I, Hennig-Pauka I, Baltes N, Trost M, Gerlach GF.	Infect Immun	10.1128/iai.73.1.226-234.2005	2005
	Identification of an Actinobacillus pleuropneumoniae consensus promoter structure.	Doree SM, Mulks MH.	J Bacteriol	10.1128/jb.183.6.1983-1989.2001	2001
Enzymology	Development of an immunomagnetic method for selective isolation of Actinobacillus pleuropneumoniae serotype 1 from tonsils.	Gagne A, Lacouture S, Broes A, D'Allaire S, Gottschalk M.	J Clin Microbiol	10.1128/jcm.36.1.251-254.1998	1998
	Genomic relatedness among Actinobacillus pleuropneumoniae field strains of sterotypes 1 and 5 isolated from healthy and diseased pigs.	Chatellier S, Harel J, Dugourd D, Chevallier B, Kobisch M, Gottschalk M.	Can J Vet Res		1999
Enzymology	ohr, Encoding an organic hydroperoxide reductase, is an in vivo-induced gene in Actinobacillus pleuropneumoniae.	Shea RJ, Mulks MH.	Infect Immun	10.1128/iai.70.2.794-802.2002	2002
	A riboflavin auxotroph of Actinobacillus pleuropneumoniae is attenuated in swine.	Fuller TE, Thacker BJ, Mulks MH.	Infect Immun	10.1128/iai.64.11.4659-4664.1996	1996
Enzymology	Presence of copper- and zinc-containing superoxide dismutase in commensal Haemophilus haemolyticus isolates can be used as a marker to discriminate them from nontypeable H. influenzae isolates.	Fung WW, O'Dwyer CA, Sinha S, Brauer AL, Murphy TF, Kroll JS, Langford PR.	J Clin Microbiol	10.1128/jcm.01376-06	2006
	Transposon mutagenesis in Actinobacillus pleuropneumoniae with a Tn10 derivative.	Tascon RI, Rodriguez-Ferri EF, Gutierrez-Martin CB, Rodriguez-Barbosa I, Berche P, Vazquez-Boland JA.	J Bacteriol	10.1128/jb.175.17.5717-5722.1993	1993
Metabolism	Identification and characterization of a DNA region involved in the export of capsular polysaccharide by Actinobacillus pleuropneumoniae serotype 5a.	Ward CK, Inzana TJ.	Infect Immun	10.1128/iai.65.6.2491-2496.1997	1997
	Cloning and mutagenesis of a serotype-specific DNA region involved in encapsulation and virulence of Actinobacillus pleuropneumoniae serotype 5a: concomitant expression of serotype 5a and 1 capsular polysaccharides in recombinant A. pleuropneumoniae serotype 1.	Ward CK, Lawrence ML, Veit HP, Inzana TJ.	Infect Immun	10.1128/iai.66.7.3326-3336.1998	1998
	Growth of Actinobacillus pleuropneumoniae is promoted by exogenous hydroxamate and catechol siderophores.	Diarra MS, Dolence JA, Dolence EK, Darwish I, Miller MJ, Malouin F, Jacques M.	Appl Environ Microbiol	10.1128/aem.62.3.853-859.1996	1996
Enzymology	Detection and molecular characterization of porcine circovirus type 2 from piglets with porcine circovirus associated diseases in Colombia.	Rincon Monroy MA, Ramirez-Nieto GC, Vera VJ, Correa JJ, Mogollon-Galvis JD.	Virol J	10.1186/1743-422x-11-143	2014
Enzymology	Multiplex PCR assay for detection of Streptococcus suis species and serotypes 2 and 1/2 in tonsils of live and dead pigs.	Marois C, Bougeard S, Gottschalk M, Kobisch M.	J Clin Microbiol	10.1128/jcm.42.7.3169-3175.2004	2004
Metabolism	Identification of a plasmid-encoded gene from Haemophilus ducreyi which confers NAD independence.	Martin PR, Shea RJ, Mulks MH.	J Bacteriol	10.1128/jb.183.4.1168-1174.2001	2001
Metabolism	The (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium) colorimetric assay for the quantitation of Actinobacillus pleuropneumoniae cytotoxin.	Chung WB, Backstrom LR, McDonald J, Collins MT.	Can J Vet Res		1993
Phylogeny	Molecular characterization of Streptococcus suis strains by 16S-23S intergenic spacer polymerase chain reaction and restriction fragment length polymorphism analysis.	Marois C, Le Devendec L, Gottschalk M, Kobisch M.	Can J Vet Res		2006
	Molecular characterization of a protective outer membrane lipoprotein (OmlA) from Actinobacillus pleuropneumoniae serotype 1.	Gerlach GF, Anderson C, Klashinsky S, Rossi-Campos A, Potter AA, Willson PJ.	Infect Immun	10.1128/iai.61.2.565-572.1993	1993
	Characterization of two genes encoding distinct transferrin-binding proteins in different Actinobacillus pleuropneumoniae isolates.	Gerlach GF, Klashinsky S, Anderson C, Potter AA, Willson PJ.	Infect Immun	10.1128/iai.60.8.3253-3261.1992	1992
	Detection of RTX toxin genes in gram-negative bacteria with a set of specific probes.	Kuhnert P, Heyberger-Meyer B, Burnens AP, Nicolet J, Frey J.	Appl Environ Microbiol	10.1128/aem.63.6.2258-2265.1997	1997
Pathogenicity	Effects of Actinobacillus pleuropneumoniae hemolysin on porcine neutrophil function.	Udeze FA, Kadis S.	Infect Immun	10.1128/iai.60.4.1558-1567.1992	1992
	Inhibition of bactericidal activity of anticapsular antibody by nonspecific antibodies reactive with surface-exposed antigenic determinants on Actinobacillus pleuropneumoniae.	Udeze FA, Kadis S.	Infect Immun	10.1128/iai.60.9.3852-3860.1992	1992
Enzymology	Pasteurellaceae isolated from tonsillar samples of commercially-reared American bison (Bison bison).	Ward AC, Dyer NW, Fenwick BW.	Can J Vet Res		1999
Phylogeny	PCR for capsular typing of Haemophilus influenzae.	Falla TJ, Crook DW, Brophy LN, Maskell D, Kroll JS, Moxon ER.	J Clin Microbiol	10.1128/jcm.32.10.2382-2386.1994	1994
	Development of the polymerase chain reaction for diagnosis of chancroid.	Chui L, Albritton W, Paster B, Maclean I, Marusyk R.	J Clin Microbiol	10.1128/jcm.31.3.659-664.1993	1993
	Prevalence of, antibody response to, and immunity induced by Haemophilus ducreyi hemolysin.	Dutro SM, Wood GE, Totten PA.	Infect Immun	10.1128/iai.67.7.3317-3328.1999	1999
	Clonal diversity in Haemophilus pleuropneumoniae.	Musser JM, Rapp VJ, Selander RK.	Infect Immun	10.1128/iai.55.5.1207-1215.1987	1987
	Cloning of a DNA fragment encoding a heme-repressible hemoglobin-binding outer membrane protein from Haemophilus influenzae.	Jin H, Ren Z, Pozsgay JM, Elkins C, Whitby PW, Morton DJ, Stull TL.	Infect Immun	10.1128/iai.64.8.3134-3141.1996	1996
	Compilation of small ribosomal subunit RNA structures.	Neefs JM, Van de Peer Y, De Rijk P, Chapelle S, De Wachter R.	Nucleic Acids Res	10.1093/nar/21.13.3025	1993
Pathogenicity	Actinobacillus pleuropneumoniae: An Update on Epidemiology, Biovar, Serotyping, Virulence, and Laboratory Diagnosis.	To H, Frey J, Gottschalk M, Sugiura K, Nagai S.	Microbiol Immunol	10.1111/1348-0421.70017	2025
	Recombinant fusion protein LpxC-ApxIVA elicits a protective immune response against Glaesserella parasuis and Actinobacillus pleuropneumoniae in mice.	Jia Y, Han J, Wang L, Han K, Wang H, Yin R, Ma Y, Zhou Y, Yin R.	Microb Pathog	10.1016/j.micpath.2025.108164	2025
	Septic shock in pigs infected, vaccinated and challenged with Actinobacillus pleuropneumoniae: A clinicopathological study.	Elvira SM, Perez JT, Ortega MET, Gallardo SG, Puente JHL, Guerrero DQ, Torres MG, Carrasco AC.	Vet J	10.1016/j.tvjl.2025.106494	2025
	Structural basis of molecular recognition of pyridoxal 5'-phosphate in a bacterial periplasmic binding protein.	Quaranta M, Pascarella S.	Biophys Chem	10.1016/j.bpc.2025.107547	2025
	Erratum for Wan et al., "Biological characteristics of mechanosensitive channels MscS and MscL in Actinobacillus pleuropneumoniae".	Wan J, Dai L, Xiao H, Zhang W, Zhang R, Xie T, Jia Y, Gao X, Huang J, Liu F.	J Bacteriol	10.1128/jb.00237-25	2025
	[Serotype-specific monitoring of Actinobacillus pleuropneumoniae in Thuringian pig farms].	Dittmar K, David K, Donat K.	Schweiz Arch Tierheilkd	10.17236/sat00463	2025
	Prevalence of porcine circoviruses (PCV2 and PCV3) in slaughtered pigs with different pleurisy lesions score: Coinfections with Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae, and Pasteurella multocida.	Braga ER, Panneitz AK, Petri FAM, de Oliveira LG.	Res Vet Sci	10.1016/j.rvsc.2025.105892	2025
	Ammonia-induced dispersion and proliferation of Actinobacillus pleuropneumoniae biofilms.	Zhang Q, Luo Z, Han W, Peng L, Tang H, Xu J, Sun Y, Zhou R, Li L.	Microb Pathog	10.1016/j.micpath.2025.108010	2025
	Optimizing the Dosage of Ceftiofur to Treat Porcine Respiratory Infection Based on a Population Pharmacokinetic Model and Monte Carlo Simulation.	Zhang C, Liu H, Kou Z, Mi K, Huang L.	J Vet Pharmacol Ther	10.1111/jvp.70032	2025
	The beta2-adrenergic receptor modulates activity of porcine alveolar macrophages in response to Actinobacillus pleuropneumoniae infection.	Xing W, Shi H, Wu W, Lu S, Fu H, Lu J, Li S, Xu B.	Dev Comp Immunol	10.1016/j.dci.2025.105420	2025
	Effect of epinephrine on growth characteristics of Actinobacillus pleuropneumoniae field isolates.	Schreiber E, Freise F, de Buhr N, Hennig-Pauka I.	J Microbiol Methods	10.1016/j.mimet.2025.107193	2025
Enzymology	Tildipirosin:A relatively new macrolide antibiotic for animals.	Shen WS, Long JY, Xu WB, Wang YH, Ning KM, Meng SY, Zhang XT, Liu ZY.	Microb Pathog	10.1016/j.micpath.2025.108108	2025
Enzymology	Florfenicol sustained-release formulation does not promote resistance emergence in non-target bacteria: hollow-fibre infection studies with pig pathogens and commensals.	Mead A, Azzariti S, Hughes A, Toutain PL, Pelligand L.	J Appl Microbiol	10.1093/jambio/lxaf200	2025
	Hyperimmune serum containing Histophilus somni rHsp60, rOMP40 and Actinobacillus pleuropneumoniae LPS antibodies as supplementary treatment for calf respiratory diseases.	Blicharski K, Bajzert J, Jawor P, Jachymek W, Kuczaj M, Stefaniak T.	Sci Rep	10.1038/s41598-025-03624-1	2025
	Effects of fisetin on virulence of Actinobacillus Pleuropneumoniae.	He Q, Ye C, Qi S, Zheng Y, Yan K, Chen Y, Chen H, Bei W.	Microb Pathog	10.1016/j.micpath.2025.107692	2025
	Actinobacillus pleuropneumoniae infection activates IL-1beta expression in porcine alveolar macrophages via beta-amyloid production.	Yan K, He Q, Tang J, Peng W, Dou B, Chen H, Bei W.	Microb Pathog	10.1016/j.micpath.2025.107559	2025
Genetics	Comparison of molecular serotyping methods for Actinobacillus pleuropneumoniae and analysis of atypical serotypes detected in routine diagnostics.	Lindhaus H, Bischoff H, Harms M, Menke T, Helmer C, Hennig-Pauka I.	J Microbiol Methods	10.1016/j.mimet.2025.107132	2025
	The antioxidant protein PntA coordinates with OmpW to resist oxidant stress in Actinobacillus pleuropneumoniae.	Han W, Zhang Q, Luo Z, Tang H, Chen X, Huang Q, Zhou R, Li L.	Vet Microbiol	10.1016/j.vetmic.2025.110500	2025
	Time series modelling of swine lung lesion prevalence to predict the temporal dynamics of Mycoplasma hyopneumoniae and Actinobacillus pleuropneumoniae infections in Spain.	Fernandez-Fontelo A, Lasierra-Morales MT, Carmona M, Sibila M, Garza-Moreno L.	Prev Vet Med	10.1016/j.prevetmed.2025.106525	2025
	Traumatic liver injury increases susceptibility to bacterial pneumonia in swine.	Kim HI, Seshadri AJ, Harbison J, Csizmadia E, Park J, Gallo D, Voltarelli VA, Scheiflinger A, Kirby JE, Hauser CJ, Otterbein LE.	J Trauma Acute Care Surg	10.1097/ta.0000000000004768	2025
Pathogenicity	Potential of recombinant CAV1-Fc in the treatment of ApxI toxin-induced damage by Actinobacillus pleuropneumoniae.	Hu Y, Zhang M, Yang G, Guo H, Jiang C, Zhou P, Chen Y, Zhang M, Ghonaim AH, Li W, He Q.	Vet Microbiol	10.1016/j.vetmic.2025.110504	2025
Pathogenicity	Porcine serum amyloid A3 promotes the adhesion, invasion, and proliferation of Actinobacillus pleuropneumoniae.	He Q, Yan K, Tang J, Gu J, Zheng Y, Dou B, Yang F, Peng M, Tian Y, Chen H, Bei W.	Microb Pathog	10.1016/j.micpath.2025.107322	2025
	Characterization and In vivo Evaluation of Polymorphic Valnemulin Hydrogen Fumarate.	Xinle Z, Li Z, Jian L, Hui Z, Jinhua G, Hejia W.	Curr Drug Deliv	10.2174/0115672018289236240530095059	2025
Pathogenicity	The Actinobacillus pleuropneumoniae apxIV operon encodes an antibacterial toxin-immunity pair.	Slivenecka E, Jurnecka D, Holubova J, Stanek O, Brazdilova L, Cizkova M, Bumba L.	Microbiol Res	10.1016/j.micres.2024.128043	2025
	Serotype distribution of Actinobacillus pleuropneumoniae isolated from diseased pigs in Argentina (2020-2024).	Cane VI, Gottschalk M, Vincent AT, Cane FD, Sarradell JE, Cane JL, Pereyra NB.	Can J Vet Res		2025
	[New drugs for horses and production animals in 2024].	Kamutzki CJ, Emmerich IU.	Tierarztl Prax Ausg G Grosstiere Nutztiere	10.1055/a-2559-5769	2025
	A new subtype of serovar 6, K6b:O3, of Actinobacillus pleuropneumoniae based on genotypic analysis.	To H, Tsutsumi N, Kon M, Kawashima N, Koike F, Lacouture S, Gottschalk M, Frey J, Nagai S.	Vet Microbiol	10.1016/j.vetmic.2024.110291	2024
	Assessment of real-time PCR test in oral fluid samples for screening the serotypes of Actinobacillus pleuropneumoniae circulating in swine herds.	Arnal JL, Fernandez AB, Lacotoure S, Benito AA, Lazaro-Gaspar S, Gottschalk M.	Vet Microbiol	10.1016/j.vetmic.2024.110268	2024
	Two HbpA-like proteins HbpA1 and HbpA2 from Actinobacillus pleuropneumoniae protect bacteria from sulfur source limitation, oxidative and cold stresses, but not essential to virulence.	Zhang M, Li Z, Hu H, Liu J, Qi C.	Gene	10.1016/j.gene.2024.148875	2024
Genetics	Genome analysis of Actinobacillus pleuropneumoniae strain APPFJLYC01 reveals multidrug resistance and high virulence potential.	Fang Z, Lin Z, Duan C, Liu X, Luo Z, Huang C, Li X, Zheng X.	PLoS One	10.1371/journal.pone.0336060	2025
	Emerging resistance to florfenicol in Actinobacillus pleuropneumoniae isolates on two Italian pig farms.	Brenciani A, Coccitto SN, Cucco L, Ustulin M, Albini E, Paniccia M, Vio D, Cinthi M, Giovanetti E, Massacci FR, Magistrali CF.	Vet Microbiol	10.1016/j.vetmic.2024.110186	2024
Pathogenicity	Atypical Actinobacillus pleuropneumoniae serotype 12 strains with a higher virulence potential.	Vincent AT, Lacouture S, St-Jean G, Tapia R, Payen S, Kon M, Frey J, To H, Gottschalk M.	Vet Res	10.1186/s13567-025-01579-9	2025
Genetics	An investigation of the transmission of Actinobacillus pleuropneumoniae within vertically integrated systems using whole genome sequencing.	Vilaro A, Karstensen KT, Cavaco LM, Angen O, Sole E, Sero I, Novell E, Enrique-Tarancon V, Guitart-Matas J, Migura-Garcia L, Fraile L.	Vet Microbiol	10.1016/j.vetmic.2024.110157	2024
	Post-outbreak dynamics and persistence of Actinobacillus pleuropneumoniae serotype 15 in finisher pigs in Iowa.	de Almeida MN, Pineyro PP, Holtkamp D, Machado I, Silva APS, Cezar G, Thomas P, Gottschalk M, Michael AA.	Vet Res	10.1186/s13567-025-01538-4	2025
	Detection of infectious agents in lungs of slaughtered pigs in association with cranioventral pulmonary consolidation.	Dors A, Klimowicz-Bodys MD, Kuberka Z, Nowak A, Zebek S, Urbaniak K, Szymanek K, Rzasa A.	J Vet Res	10.2478/jvetres-2025-0049	2025
	A kinetic model reveals the critical gating motifs for donor-substrate loading into Actinobacillus pleuropneumoniae N-glycosyltransferase.	Hao Z, Guo Q, Peng W, Da LT.	Phys Chem Chem Phys	10.1039/d3cp06034a	2024
	A serological survey of wild boar in Serbia for Mycoplasma hyopneumoniae and Actinobacillus pleuropneumoniae.	Ninkovic M, Zoric JM, Vojinovic D, Veljovic L, Jezdimirovic N, Kureljusic J, Zutic J.	Vet Med (Praha)	10.17221/64/2024-vetmed	2024
	Characterization of Actinobacillus pleuropneumoniae biovar 2 isolates reportedly reacted with the serovar 4 antiserum, and development of a multiplex PCR for O-antigen typing.	To H, Maldonado J, Tsutsumi N, Gottschalk M, Frey J, Nagai S.	Vet Microbiol	10.1016/j.vetmic.2024.110030	2024
	A Florfenicol-Resistant Plasmid Shuttling Between Actinobacillus pleuropneumoniae and Glaesserella parasuis.	Zhu C, Cai J, An J, Zhang B, Li Y.	Microb Drug Resist	10.1089/mdr.2023.0127	2024
	Testosterone and estradiol regulate the expression of proteases and a hemoglobinase in Actinobacillus seminis.	Ramirez-Paz-Y-Puente GA, Gutierrez-Pabello JA, Zenteno E, Villamar-Duque TE, Meneses-Romero EP, Vazquez-Cruz C, Negrete-Abascal E.	FEMS Microbiol Lett	10.1093/femsle/fnaf097	2025
	Bactericidal Activity of Pradofloxacin and Other Antimicrobials Against Swine Respiratory Bacterial Pathogens.	Blondeau JM, Fitch SD.	Pathogens	10.3390/pathogens14111171	2025
Pathogenicity	Effect of age and disease on saliva and serum biomarkers of stress, inflammation, immunity, redox and general health status in pigs.	Tecles F, Martinez-Martinez A, Crespo-Piazuelo D, Lopez-Martinez MJ, Yeste-Vizcaino N, Goyena E, Ceron JJ, Martinez-Subiela S, Gonzalez-Bulnes A, Munoz-Prieto A.	Sci Rep	10.1038/s41598-025-10203-x	2025
	Discovery of a Novel Integrative Conjugative Element ICEAplChn2 Related to SXT/R391 in Actinobacillus pleuropneumoniae.	Cai J, Geng Y, Zhang B, Li Y.	Microb Drug Resist	10.1089/mdr.2023.0108	2024
	Rhein kills Actinobacillus pleuropneumoniae, reduces biofilm formation, and effectively treats bacterial lung infections in mice.	Ding H, Bai Y, Luo W, Li H, Zhu C, Zhao X, Sun H, Wen Y, Zhang W, Zhang S, Wen B, Wang R, Zhang L, Liu X, Shen J, Hu J, Wang L, Bai Y, Liao C, Wu Y, Wu X, Ding K.	J Med Microbiol	10.1099/jmm.0.001826	2024
Pathogenicity	Effects of OxyR regulator on oxidative stress, Apx toxin secretion and virulence of Actinobacillus pleuropneumoniae.	Guo F, Quan R, Cui Y, Cao X, Wen T, Xu F.	Front Cell Infect Microbiol	10.3389/fcimb.2023.1324760	2023
	The Arms Race Between Actinobacillus pleuropneumoniae and Its Genetic Environment: A Comprehensive Analysis of Its Defensome and Mobile Genetic Elements.	da Silva GC, Rossi CC.	Mol Microbiol	10.1111/mmi.15374	2025
	The cAMP receptor protein gene contributes to growth, stress resistance, and colonization of Actinobacillus pleuropneumoniae.	He Q, Zheng Y, Yan K, Tang J, Yang F, Tian Y, Yang L, Dou B, Chen Y, Gu J, Chen H, Yuan F, Bei W.	Vet Microbiol	10.1016/j.vetmic.2024.110006	2024
	The first detection of swine orthopneumovirus in a pig farm in Sweden: a case report.	Breukers E, Kim H, Banihashem F, Andersson K, Leijon M, Westin R, Sjolund M, Zohari S.	Porcine Health Manag	10.1186/s40813-025-00473-2	2025
Genetics	Isolation, Antimicrobial Susceptibility, and Genotypes of Three Pasteurellaeae Species Prevalent on Pig Farms in China Between 2021 and 2023.	Li F, Zong X, Chen G, Zhang Y, Cao Q, Li L, Chen H, Peng Z, Tan C.	Microorganisms	10.3390/microorganisms13040938	2025
	ISApl4, a New IS1595 Family Insertion Sequence Forming a Novel Pseudo-Compound Transposon That Confers Antimicrobial Multidrug Resistance in Actinobacillus pleuropneumoniae.	Bosse JT, Li Y, Stegger M, Cohen LM, Angen O, Overballe-Petersen S, Hanke D, Schwarz S, Langford PR, Kruger-Haker H.	Antibiotics (Basel)	10.3390/antibiotics14101021	2025
	The Vehicle of Administration and Prandial State May Reduce the Spectrum of Oral Broad-Spectrum Antibiotics (Oxytetracycline, Fosfomycin and Amoxicillin) Administered to Piglets: A Pharmacokinetic/Pharmacodynamic Approach.	Decundo JM, Dieguez SN, Martinez G, Amanto FA, Perez Gaudio DS, Soraci AL.	J Vet Pharmacol Ther	10.1111/jvp.13479	2025
	Serovars and antimicrobial resistance profiles of Actinobacillus pleuropneumoniae isolates from clinical-case pigs in Taiwan.	Kwan WF, Li Y, Bosse JT, Chiou MT, Chiu HJ, Langford PR, Mortensen P, Lin CN.	BMC Vet Res	10.1186/s12917-025-04878-7	2025
	First isolation of Aerococcus viridans from clinical specimens collected on a pig farm in Poland.	Cybulski P, Kondratiuk R, Spiekermeier I, Wozniakowski G.	J Vet Res	10.2478/jvetres-2024-0058	2024
Genetics	Characterization of Actinobacillus pleuropneumoniae isolated from pigs in Japan using whole genome sequencing.	Ozawa M, Kawano M, Abo H, Issiki Y, Kumakawa M, Kawanishi M, Kojima A, Iwamoto S.	Comp Immunol Microbiol Infect Dis	10.1016/j.cimid.2023.102062	2023
	Native ApxIIA secreted by Actinobacillus pleuropneumoniae induces apoptosis in porcine alveolar macrophages dependent on concentration and acylation.	Tang H, Wang R, Pang S, Han W, Zhang Q, Fang Q, Chen X, Huang Q, Qiu D, Zhou R, Li L.	Vet Microbiol	10.1016/j.vetmic.2023.109908	2023
	Structural insights in to the atypical type-I ABC Glucose-6-phosphate importer VCA0625-27 of Vibrio cholerae.	Saha I, Ghosh B, Dasgupta J.	Biochem Biophys Res Commun	10.1016/j.bbrc.2024.150030	2024
	Development and Application of Fluorescent and Lateral Flow Dipstick Recombinase-Aided Amplification for Rapid Detection of Glaesserella parasuis	Che Y, Wang Y, Wu R, Wang L, Wu X, Chen Q, Chen R, Zhou L.	Vet Sci		2025
	Halicin: A New Horizon in Antibacterial Therapy against Veterinary Pathogens.	Wang S, Zhao K, Chen Z, Liu D, Tang S, Sun C, Chen H, Wang Y, Wu C.	Antibiotics (Basel)	10.3390/antibiotics13060492	2024
	Distribution of Streptococcus suis, Actinobacillus pleuropneumoniae, and Glaesserella parasuis serotypes isolated from diseased pigs in Quebec between January 2020 and December 2023.	Lacouture S, Vincent AT, Gottschalk M.	Can Vet J		2024
Genetics	Serotyping of Actinobacillus pleuropneumoniae based on whole genome sequencing: validation of a bioinformatic tool.	Angen O, Karstensen KT, Vilaro A, Cavaco LM, Langford PR, Sauce LJF, Migura-Garcia L, Salomonsen CM, Li Y, Bosse JT.	Microb Genom	10.1099/mgen.0.001434	2025
	Serotyping and antimicrobial resistance of Actinobacillus pleuropneumoniae isolates from fattening pigs in Poland from 2019 to 2024.	Paulina P, Dawid T.	BMC Vet Res	10.1186/s12917-025-04504-6	2025
	Comparison of the Minimum Inhibitory and Mutant Prevention Drug Concentrations for Pradofloxacin and 7 Other Antimicrobial Agents Tested Against Swine Isolates of Actinobacillus pleuropneumoniae and Pasteurella multocida.	Blondeau JM, Fitch SD.	Molecules	10.3390/molecules29225448	2024
	Evaluation of Transport Time on Stress Biomarkers in Pigs.	Currie S, Swindle MM, Suckow MA, Zhang JQ, Adusumilli S.	Vet Med Sci	10.1002/vms3.70511	2025
	Mass cytometry analysis reveals a cross-tissue immune landscape in Actinobacillus pleuropneumoniae-induced pneumonia.	Tian Y, Jiang X, Bao C, Abdelaal T, Chen D, Wang W, Li F, Lei L, Li N.	Microbiol Spectr	10.1128/spectrum.02665-24	2025
	Novel Soluble apxIVA-Truncated Protein and Its Application to Rapid Detection and Distinction of Actinobacillus pleuropneumoniae Wild-Strain-Infected Samples from Those Vaccinated with apxIV-Partially Deleted Vaccine.	Rao J, Liu X, Zhu X, Qi Y, Chen H, Bei W.	Vet Sci	10.3390/vetsci12030278	2025
	Detection and differentiation of seven porcine respiratory pathogens using a multiplex ligation-dependent probe amplification assay.	Zhou Y, Yu H, Zhao X, Ni J, Gan S, Dong W, Du J, Zhou X, Wang X, Song H.	Vet J	10.1016/j.tvjl.2024.106124	2024
	Impact of bronchoalveolar lavage from influenza A virus diseased pigs on neutrophil functions and growth of co-infecting pathogenic bacteria.	Lassnig S, Hennig-Pauka I, Bonilla MC, Morgelin M, Imker R, von Kockritz-Blickwede M, de Buhr N.	Front Immunol	10.3389/fimmu.2024.1325269	2024
Enzymology	Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs.	Sjolund M, Rosendal T, Wallgren P, Pringle M, Bondesson U, Bengtsson B, Ekstrand C.	Acta Vet Scand	10.1186/s13028-025-00806-9	2025
	Pathological analysis and etiological assessment of pulmonary lesions and its association with pleurisy in slaughtered pigs.	Arruda LP, Malcher C, Petri FAM, da Silva DG, Storino GY, Almeida HMS, Sonalio K, Toledo LT, de Oliveira LG.	Vet Microbiol	10.1016/j.vetmic.2024.110039	2024
	Development and application of a dual LAMP-LFD assay for the simultaneous detection of Streptococcus suis and Glaesserella parasuis.	Wang H, Dong C, Tian X, Pan Y, Wang L, An T, Zhu L.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1575365	2025
	Temporal and Serotypic Dynamics of Actinobacillus pleuropneumoniae in South African Porcine Populations: A Retrospective Study from 1985 to 2023.	Seakamela EM, Henton MM, Jonker A, Kayoka-Kabongo PN, Matle I.	Pathogens	10.3390/pathogens13070599	2024
	Tracheal epithelial cell-exosome-derived MiR-21-5p inhibits alveolar macrophage pyroptosis to resist pulmonary bacterial infection through PIK3CD-autophagy pathway.	Wang J, Gan L, Li F, Li Q, Wu T, Wu Z, Chen P, Scicluna BP, Feng X, Gu J, Han W, Li N, Lei L.	Life Sci	10.1016/j.lfs.2023.122340	2024
Pathogenicity	Review of advanced research on swine Actinobacillus pleuropneumoniae vaccine development strategy.	Tesfaye AB, Han R, Tao Z, You L, Zhu J, Gao P, Fu L, Chu Y.	Front Immunol	10.3389/fimmu.2025.1645610	2025
	Probing enzymatic properties of N-glycosyltransferase isoforms from Mannheimia haemolytica.	Liu Z, Liu X, Rong Y, Chen M.	Carbohydr Res	10.1016/j.carres.2023.108947	2023
	Serotype diversity of Actinobacillus pleuropneumoniae detected by real-time PCR in clinical and subclinical samples from Spanish pig farms during 2017-2022.	Arnal Bernal JL, Gottschalk M, Lacotoure S, Sanz Tejero C, Chacon Perez G, Martin-Jurado D, Fernandez Ros AB.	Vet Res	10.1186/s13567-024-01419-2	2024
	Suspected aerosol transmission of swine pathogens: A field case.	Desrosiers R, Kluber E.	Can Vet J		2024
	Comparison of antimicrobial susceptibility of Glaesserella parasuis from different pig production systems in Taiwan between 2015 and 2020.	Lin WH, Liou ZW, Lin SM, Yang CY, Lin CF, Chang YF, Lin CN, Chiou MT.	Porcine Health Manag	10.1186/s40813-025-00427-8	2025
	IL-21-dependent Ly6C⁺Ly6G⁺CD4⁺ T cells found in lung enhance macrophages function against Actinobacillus pleuropneumoniae infection in mice.	Bao C, Jiang X, Tian Y, Wang W, Xiao J, Liu B, Chen P, Li Z, Li J, Zhu J, Abdelaal T, Chen D, Li N, Lei L.	Cell Death Discov	10.1038/s41420-025-02742-z	2025
	Effects of oil-based adjuvants on the immune response of pigs after dermal administration of antigen and evaluation of the immunization level after a subsequent Actinobacillus pleuropneumoniae challenge in pigs.	Jarosova R, Ben Arous J, Nechvatalova K, Nedbalcova K, Hlavova K, Stepanova H, Leva L, Oreskovic Z, Jan Matiasovic, Versille N, Sladek Z, Faldyna M.	Vet Microbiol	10.1016/j.vetmic.2022.109607	2023
	Environmental enrichment affects immunity and reduces disease severity in pigs after co-infection, with stronger effects when applied from birth than from weaning.	de Bruijn BGC, van Dixhoorn IDE, Bolhuis JE, Cornelissen JBWJ, Stockhofe-Zurwieden N, Kluivers M, Rebel JMJ.	Front Vet Sci	10.3389/fvets.2024.1511209	2024
Genetics	The Challenge of Developing a Test to Differentiate Actinobacillus pleuropneumoniae Serotypes 9 and 11.	Arnal Bernal JL, Fernandez Ros AB, Lacouture S, Bosse JT, Fodor L, Gantelet H, Solans Bernad L, Li Y, Langford PR, Gottschalk M.	Microorganisms	10.3390/microorganisms13020280	2025
	Antimicrobial susceptibility among respiratory tract pathogens isolated from diseased cattle and pigs from different parts of Europe.	de Jong A, Morrissey I, Rose M, Temmerman R, Klein U, Simjee S, El Garch F.	J Appl Microbiol	10.1093/jambio/lxad132	2023
	Development and Characterization of a Recombinant galT-galU Protein for Broad-Spectrum Immunoprotection Against Porcine Contagious Pleuropneumonia.	Chen JY, Deng Y, Liu J, Wen X, Cao YQ, Mu Y, Sun M, Miao C, Peng Z, Lu K, Wang YL, Chen X, Pang S, Wang D, Zhou J, Li M, Wen Y, Wu R, Zhao S, Lang YF, Yan QG, Huang X, Du S, Wang Y, Han X, Cao SJ, Zhao Q.	Int J Mol Sci	10.3390/ijms26083634	2025
	Hyper-production of porcine contagious pleuropneumonia subunit vaccine proteins in Escherichia coli by developing a bicistronic T7 expression system.	Sun M, Gao AX, Li A, Ledesma-Amaro R, Wang P, Chen W, Bai Z, Liu X.	Biotechnol J	10.1002/biot.202300187	2024
Enzymology	Delivery strategies to improve piglets exposure to oral antimicrobials.	Hernandez N, Roques BB, Lacroix MZ, Concordet D.	BMC Vet Res	10.1186/s12917-024-04334-y	2024
	Evaluating the Immunogenic Potential of ApxI and ApxII from Actinobacillus pleuropneumoniae: An Immunoinformatics-Driven Study on mRNA Candidates.	Deng Y, Chen JY, Wang Y, Wang YL, Liu J, Peng Z, Zhou J, Lu K, Wen X, Chen X, Pang S, Wang D, Li M, Du S, Cao SJ, Zhao Q.	Vet Sci	10.3390/vetsci12050414	2025
	Actinobacillus pleuropneumoniae Serotypes by Multiplex PCR Identification and Evaluation of Lung Lesions in Pigs from Piedmont (Italy) Farms.	Cuccato M, Divari S, Ciaramita S, Sereno A, Campelli D, Biolatti PG, Biolatti B, Meliota F, Bollo E, Cannizzo FT.	Animals (Basel)	10.3390/ani14152255	2024
Proteome	Proteomic and immunoproteomic insights into the exoproteome of Actinobacillus pleuropneumoniae, the causative agent of porcine pleuropneumonia.	Stancheva SG, Frombling J, Sassu EL, Hennig-Pauka I, Ladinig A, Gerner W, Grunert T, Ehling-Schulz M.	Microb Pathog	10.1016/j.micpath.2022.105759	2022
Enzymology	Susceptibility evaluation and PK/PD integration of tulathromycin against Actinobacillus pleuropneumoniae during the mutant selection window.	Wang H, Zhang L.	Front Vet Sci	10.3389/fvets.2024.1407907	2024
	Serovar and multilocus sequence typing analysis of Pasteurella multocida from diseased pigs in Taiwan.	Wu CF, Liao CC, Chou CC, Wang CM, Huang SW, Kuo HC.	BMC Vet Res	10.1186/s12917-025-04595-1	2025
	HtrA of Actinobacillus pleuropneumoniae is a virulence factor that confers resistance to heat shock and oxidative stress.	Zhang L, Zhao F, Xu H, Chen Y, Qi C, Liu J.	Gene	10.1016/j.gene.2022.146771	2022
	Biological characteristics of mechanosensitive channels MscS and MscL in Actinobacillus pleuropneumoniae.	Wan J, Dai L, Xiao H, Zhang W, Zhang R, Xie T, Jia Y, Gao X, Huang J, Liu F.	J Bacteriol	10.1128/jb.00429-23	2024
	Examination of the Virulence of Actinobacillus pleuropneumoniae Serovar 16 in Pigs.	Tenk M, Toth G, Marton Z, Sarkozi R, Szoradi A, Makrai L, Palmai N, Szalai T, Albert M, Fodor L.	Vet Sci	10.3390/vetsci11020062	2024
Pathogenicity	An Experimental Dermal Oedema Model for Apx Toxins of Actinobacillus pleuropneumoniae.	Soutter F, Priestnall SL, Catchpole B, Rycroft AN.	J Comp Pathol	10.1016/j.jcpa.2022.04.004	2022
	Lung microdialysis and in vivo PK/PD integration of cefquinome against Actinobacillus pleuropneumoniae in a porcine experimental lung infection model.	Chen Y, Li M, Su D, Xiong S, Feng Y, Deng Q, Ding H.	Front Vet Sci	10.3389/fvets.2024.1390336	2024
	Rapid detection of Actinobacillus pleuropneumoniae targeting the apxIVA gene for diagnosis of contagious porcine pleuropneumonia in pigs by polymerase spiral reaction.	Sarkar R, Roychoudhury P, Kumar S, Dutta S, Konwar N, Subudhi PK, Dutta TK.	Lett Appl Microbiol	10.1111/lam.13749	2022
	Histopathological lesions of Actinobacillus pleuropneumoniae serotype 8 in infected pigs.	Papatsiros VG, Stylianaki I, Tsokana CN, Papakonstantinou G, Christophorou M, Papaioannou N, Athanasiou LV.	Vet Res Forum	10.30466/vrf.2022.556971.3539	2023
Genetics	Identification of genes that differentiate Mannheimia haemolytica genotypes 1 and 2 using a pangenome approach.	Deschner D, Hill JE.	PLoS One	10.1371/journal.pone.0325338	2025
	Immunogenicity and vaccine efficacy of Actinobacillus pleuropneumoniae-derived extracellular vesicles as a novel vaccine candidate.	Hyun Park S, Kim YH, Lee HJ, Han JM, Seo BJ, Park GS, Kim C, Ryu YB, Kim WS.	Virulence	10.1080/21505594.2025.2453818	2025
Genetics	Antimicrobial susceptibility and resistome of Actinobacillus pleuropneumoniae in Taiwan: a next-generation sequencing analysis.	Ke CH, Lai PY, Hsu FY, Hsueh PR, Chiou MT, Lin CN.	Vet Q	10.1080/01652176.2024.2335947	2024
Enzymology	Hollow-fibre infection model: adaptations for the culture and assessment of fastidious organisms.	Mead A, Azzariti S, Pelligand L.	Access Microbiol	10.1099/acmi.0.000744.v3	2024
	Cytokine expression by CD163+ monocytes in healthy and Actinobacillus pleuropneumoniae-infected pigs.	Jarosova R, Ondrackova P, Leva L, Nedbalcova K, Vicenova M, Masek J, Volf J, Gebauer J, Do T, Guran R, Sladek Z, Dominguez J, Faldyna M.	Res Vet Sci	10.1016/j.rvsc.2022.07.015	2022
	Serotype diversity and antimicrobial susceptibility profiles of Actinobacillus pleuropneumoniae isolated in Italian pig farms from 2015 to 2022.	Guarneri F, Romeo C, Scali F, Zoppi S, Formenti N, Maisano AM, Catania S, Gottschalk M, Alborali GL.	Vet Res	10.1186/s13567-024-01305-x	2024
Genetics	Outer membrane vesicles secreted from Actinobacillus pleuropneumoniae isolate disseminating the floR resistance gene to Enterobacteriaceae.	Xu M, Ke H, Zang Y, Gou H, Yang D, Shi K, Zhang K, Li Y, Jiang Z, Chu P, Zhai S, Li C.	Front Microbiol	10.3389/fmicb.2024.1467847	2024
	Effect of Carbonyl Cyanide Chlorophenylhydrazone on Intrabacterial Concentration and Antimicrobial Activity of Amphenicols against Swine Resistant Actinobacillus pleuropneumoniae and Pasteurella multocida.	Rattanapanadda P, Kuo HC, Chang SK, Tell LA, Shia WY, Chou CC.	Vet Res Commun	10.1007/s11259-022-09917-4	2022
	IL-5 enhances the resistance of Actinobacillus pleuropneumoniae infection in mice through maintaining appropriate levels of lung M2, PMN-II and highly effective neutrophil extracellular traps.	Chen P, Bao C, Zhu R, Wang J, Zhu J, Li Z, Li F, Gu J, Feng X, Li N, Lei L.	Vet Microbiol	10.1016/j.vetmic.2022.109438	2022
	Synergistic fermentation of Cordyceps militaris and herbal substrates boosts grower pig antioxidant and immune function.	Pi CC, Cheng YC, Chen CC, Lee JW, Lin CN, Chiou MT, Chen HW, Chiu CH.	BMC Vet Res	10.1186/s12917-024-04338-8	2024
	Untargeted and targeted metabolomics reveal that adenosine nucleotides released in Actinobacillus pleuropneumoniae supernatant inhibit porcine reproductive and respiratory syndrome virus replication.	Salmin AF, Pesant MJ, Burgher Y, Provost C, Labrie J, Jacques M, Gagnon CA, Beaudry F.	Talanta	10.1016/j.talanta.2022.123315	2022
	Health-Economic Impact Attributable to Occurrence of Pleurisy and Pneumonia Lesions in Finishing Pigs.	Malcher CS, Petri FAM, Arruda LP, de Aguiar GA, Storino GY, Sonalio K, Toledo LT, Hirose F, Oliveira LG.	Vet Sci	10.3390/vetsci11120668	2024
Pathogenicity	Hyperimmune serum containing Histophilus somni rHsp60, rOMP40 and Actinobacillus pleuropneumoniae LPS antibodies as supplementary treatment for calf respiratory diseases	Blicharski K, Bajzert J, Jawor P, Jachymek W, Kuczaj M, Stefaniak T.	Sci Rep		2025
	Pulmonary lesions with asteroid bodies in a pig experimentally infected with Actinobacillus pleuropneumoniae serovar 15.	To H, Konnai M, Teshima K, Tsutsumi N, Ito S, Sato M, Shibuya K, Nagai S.	J Vet Med Sci	10.1292/jvms.23-0202	2023
	Development and application of a quadruplex TaqMan fluorescence quantitative PCR typing method for Streptococcus suis generalis, type 2, type 7 and type 9.	Wang H, Chen J, Sun Y, An T, Wang Y, Chen H, Yu C, Xia C, Zhang H.	Front Cell Infect Microbiol	10.3389/fcimb.2024.1475878	2024
	Proposal of a subtype of serovar 4, K4b:O3, of Actinobacillus pleuropneumoniae based on serological and genotypic analysis.	To H, Kon M, Koike F, Shibuya K, Nagai S, Gottschalk M, Frey J, Sasakawa C.	Vet Microbiol	10.1016/j.vetmic.2021.109279	2021
Enzymology	Gut microbiome perturbation and its correlation with tylosin pharmacokinetics in healthy and infected pigs.	Lee EB, Lee GY, Hossain MA, Awji EG, Park SC.	Sci Rep	10.1038/s41598-024-69566-2	2024
	Exploring the Genetic Diversity of Mycoplasma hyopneumoniae in Pigs with Pneumonia and Pleurisy at Slaughter.	Panneitz AK, Braga ER, Petri FAM, Menegatt JCO, Driemeier D, Maes D, Oliveira LG.	Microorganisms	10.3390/microorganisms12101988	2024
	An improved multiplex PCR for Actinobacillus pleuropneumoniae, Glaesserella australis and Pasteurella multocida.	Sun X, Blackall PJ, Daniel P, Chandra K, Jenkin S, Turni C.	J Microbiol Methods	10.1016/j.mimet.2021.106360	2021
	The two-component system CpxAR is required for the high potassium stress survival of Actinobacillus pleuropneumoniae.	Wan J, Zhang R, Jia Y, Xie T, Dai L, Yao Q, Zhang W, Xiao H, Gao X, Huang J, Bei W, Liu F.	Front Microbiol	10.3389/fmicb.2023.1259935	2023
	Supramolecular assembly of multifunctional protein gels via an N-glycosylation consensus sequence fusion domain.	Hill ED, Michel S, Sequeira NR, Keselowsky BG, Hudalla GA.	Mol Syst Des Eng	10.1039/d4me00029c	2024
	Application of the MISTEACHING(S) disease susceptibility framework to Actinobacillus pleuropneumoniae to identify research gaps: an exemplar of a veterinary pathogen.	Langford PR, Stringer OW, Li Y, Bosse JT.	Anim Health Res Rev	10.1017/s1466252321000074	2021
	Prevalence of pathogens from clinical samples associated with porcine respiratory and digestive diseases in South Korea from 2021 to 2023.	Wang HY, Song JK, Shin S, Kim H.	Front Vet Sci	10.3389/fvets.2025.1461935	2025
	Relationships between pig farm management and facilities and lung lesions' scores and between lung lesions scores and carcass characteristics.	Kuberka Z, Mee JF, Walaszek-Kayaoglu A, Klimowicz-Bodys MD, Dors A, Rzasa A.	BMC Vet Res	10.1186/s12917-024-03968-2	2024
	Evaluation the kill rate and mutant selection window of danofloxacin against Actinobacillus pleuropneumoniae in a peristaltic pump model.	Wang H, Liao C, Ding K, Zhang L, Wang L.	BMC Vet Res	10.1186/s12917-024-04016-9	2024
	Characterization of nonencapsulated Actinobacillus pleuropneumoniae serovar K12:O3 isolates.	To H, Tsutsumi N, Ito S, Gottschalk M, Nagai S.	J Vet Diagn Invest	10.1177/10406387231190875	2023
	Susceptibility trends of swine respiratory pathogens from 2019 to 2022 to antimicrobials commonly used in Spain.	Vilaro A, Novell E, Enrique-Tarancon V, Baliellas J, Fraile L.	Porcine Health Manag	10.1186/s40813-023-00341-x	2023
	Brazilian Clinical Strains of Actinobacillus pleuropneumoniae and Pasteurella multocida: Capsular Diversity, Antimicrobial Susceptibility (In Vitro) and Proof of Concept for Prevention of Natural Colonization by Multi-Doses Protocol of Tildipirosin.	Kuchiishi SS, Ramos Prigol S, Bresolin E, Fernandes Lenhard B, Pissetti C, Garcia-Iglesias MJ, Gutierrez-Martin CB, Martinez-Martinez S, Kreutz LC, Frandoloso R.	Antibiotics (Basel)	10.3390/antibiotics12121658	2023
	Biofilm formation in Streptococcus suis: in vitro impact of serovars and assessment of coinfections with other porcine respiratory disease complex bacterial pathogens.	Miguelez-Perez R, Mencia-Ares O, Gutierrez-Martin CB, Gonzalez-Fernandez A, Petrocchi-Rilo M, Delgado-Garcia M, Martinez-Martinez S.	Vet Res	10.1186/s13567-024-01412-9	2024
Phylogeny	Presence and Characterisation of Porcine Respirovirus 1 (PRV1) in Northern Italy.	Sozzi E, Leo G, Bertasio C, Alborali GL, Salogni C, Tonni M, Formenti N, Lelli D, Moreno A, Trogu T, Canziani S, Tolini C, Cerioli MP, Lavazza A.	Pathogens	10.3390/pathogens13010085	2024
	In vitro susceptibility of swine pathogens to feed additives and active ingredients with potential as antibiotic replacements.	Neath C, Portocarero N, Jones C.	J Appl Microbiol	10.1111/jam.15318	2022
	Production of microhomogeneous glycopeptide by a mutated NGT according FuncLib with unique sugar as substrate.	Liu Z, Li K, Liu X, Zhao J, Yu Y, Wang L, Kong Y, Chen M.	Enzyme Microb Technol	10.1016/j.enzmictec.2021.109949	2022
	Actinobacillus pleuropneumoniae FliY and YdjN are involved in cysteine/cystine utilization, oxidative resistance, and biofilm formation but are not determinants of virulence.	Zhao F, Xu H, Chen Y, Xiao J, Zhang M, Li Z, Liu J, Qi C.	Front Microbiol	10.3389/fmicb.2023.1169774	2023
Pathogenicity	CopA Protects Actinobacillus pleuropneumoniae against Copper Toxicity.	Peng W, Peng W, Yang X, Yan K, Chen H, Yuan F, Bei W.	Vet Microbiol	10.1016/j.vetmic.2021.109122	2021
	Hypersecretion of OmlA antigen in Corynebacterium glutamicum through high-throughput based development process.	Sun M, Gao AX, Ledesma-Amaro R, Li A, Wang R, Nie J, Zheng P, Yang Y, Bai Z, Liu X.	Appl Microbiol Biotechnol	10.1007/s00253-022-11918-x	2022
	Field Evaluation of a Ready-to-Use Porcine Circovirus Type 2 and Mycoplasma hyopneumoniae Vaccine in Naturally Infected Farms in Taiwan.	Hsueh FC, Chien CY, Chang SW, Lian BR, Lin HY, Ellerma L, Chiou MT, Lin CN.	Vet Sci	10.3390/vetsci12040304	2025
	The Susceptibility Trends of Respiratory and Enteric Porcine Pathogens to Last-Resource Antimicrobials.	Vilaro A, Novell E, Enrique-Tarancon V, Baliellas J, Migura-Garcia L, Fraile L.	Antibiotics (Basel)	10.3390/antibiotics12111575	2023
	Discovery of viruses and bacteria associated with swine respiratory disease on farms at a nationwide scale in China using metatranscriptomic and metagenomic sequencing.	Huang X, Yao X, Song W, Zhao M, Zhu Z, Liu H, Song X, Huang J, Chen Y, Wang Z, Peng C, Wu W, Yang H, Hua L, Chen H, Wu B, Peng Z.	mSystems	10.1128/msystems.00025-25	2025
	RPA-CRISPR/Cas12a-Based Detection of Haemophilus parasuis.	Zhang K, Sun Z, Shi K, Yang D, Bian Z, Li Y, Gou H, Jiang Z, Yang N, Chu P, Zhai S, Wei Z, Li C.	Animals (Basel)	10.3390/ani13213317	2023
Metabolism	Molecular and functional characterization of HtrA protein in Actinobacillus pleuropneumoniae.	Xu K, Zhao Q, Jiang HZ, Mou XR, Chang YF, Cao YQ, Miao C, Wu R, Wen YP, Huang XB, Yan QG, Du SY, Cao SJ.	Vet Microbiol	10.1016/j.vetmic.2021.109058	2021
	Antimicrobial Resistance of Actinobacillus pleuropneumoniae, Streptococcus suis, and Pasteurella multocida Isolated from Romanian Swine Farms.	Siteavu MI, Drugea RI, Pitoiu E, Ciobotaru-Pirvu E.	Microorganisms	10.3390/microorganisms11102410	2023
	Susceptibility of Actinobacillus pleuropneumoniae, Pasteurella multocida and Streptococcus suis Isolated from Pigs in Hungary between 2018 and 2021.	Somogyi Z, Mag P, Simon R, Kerek A, Makrai L, Biksi I, Jerzsele A.	Antibiotics (Basel)	10.3390/antibiotics12081298	2023
	A generic protocol to immobilize lipopolysaccharides on microbeads for multiplex analysis.	Boas U, Sorensen MB, Andresen LO, Berger SS.	Anal Methods	10.1039/d1ay00327e	2021
	Actinobacillus pleuropneumoniae: The molecular determinants of virulence and pathogenesis.	Nahar N, Turni C, Tram G, Blackall PJ, Atack JM.	Adv Microb Physiol	10.1016/bs.ampbs.2020.12.001	2021
Genetics	Optimization of DNA extraction methods from pig farm wastewater for pathogen detection using metagenomic sequencing.	Muralidhar M, Naseem MN, Mesa JRB, Omaleki L, Turni C.	Microb Genom	10.1099/mgen.0.001532	2025
Pathogenicity	Exposure to Sublethal Ciprofloxacin Induces Resistance to Ciprofloxacin and Cross-Antibiotics, and Reduction of Fitness, Biofilm Formation, and Apx Toxin Secretion in Actinobacillus pleuropneumoniae.	Guo F, Guo J, Cui Y, Cao X, Zhou H, Su X, Yang B, Blackall PJ, Xu F.	Microb Drug Resist	10.1089/mdr.2020.0348	2021
	Immunization of pigs with Actinobacillus pleuropneumonia live attenuated (gene-deleted) vaccine HB04M intramuscularly or intranasally exhibits remarkably rapid protection against heterologous strain challenge.	Qi S, He Q, Wei X, Liu J, Yu D, Li Y, Dong D, Chen H, Bei W.	BMC Vet Res	10.1186/s12917-025-04895-6	2025
	Evaluation of the mutant selection window of danofloxacin against Actinobacillus pleuropneumoniae in an in vitro dynamic model.	Zhang L, Wang H, Bai Y, Wang L, Bai Y, Hu J.	Front Vet Sci	10.3389/fvets.2023.1107608	2023
	Identification of novel small RNAs in extracellular vesicles produced by Actinobacillus pleuropneumoniae.	da Silva GC, Rosa JN, Fontes PP, de Castro AG, Barbosa EAA, Clarindo WR, Mantovani HC, Li Y, Bosse JT, Langford PR, Bazzolli DMS.	Front Microbiol	10.3389/fmicb.2023.1291930	2023
Enzymology	Pharmacokinetic-Pharmacodynamic Cutoff Values for Doxycycline in Pigs to Support the Establishment of Clinical Breakpoints for Antimicrobial Susceptibility Testing.	Toutain PL, Bousquet-Melou A, Ferran AA, Roques BB, Del Castillo JRE, Lees P, Croubels S, Bousquet E, Pelligand L.	J Vet Pharmacol Ther	10.1111/jvp.13511	2025
	Caspase-1 inhibitor reduced the lung injury in a mouse model of pleuropneumonia caused by Actinobacillus pleuropneumoniae.	Zhang Y, Yang T, Huang F, Zhang Y.	Pol J Vet Sci	10.24425/pjvs.2020.135807	2020
	Reproduction of porcine ear necrosis (ear-tip necrosis) following intradermal inoculation of pigs with Fusobacterium necrophorum.	Costa MO, Nosach R, de Almeida MHM.	PLoS One	10.1371/journal.pone.0337536	2025
Phylogeny	Characterization of Lung Microbiome in Subclinical Pneumonic Thai Pigs Using 16S rRNA Gene Sequencing.	Tadee P, Khaodang P, Patchanee P, Buddhasiri S, Eiamsam-Ang T, Kittiwan N, Tadee P.	Animals (Basel)	10.3390/ani15030410	2025
	Description of Sensor Placement for Continuous Glucose Monitoring in a Pig Model of Diabetes Mellitus	Perez-Guille B, Soriano-Rosales R, Rios-Garcia L, Gonzalez-Ortiz A, Gonzalez-Zamora J, Monroy-Santoyo S, Cedillo-Pelaez C, Avendano-Estrada A, Trujillo-Ortega M.	J Am Assoc Lab Anim Sci		2025
Phylogeny	Isolation of Biotype 1 Serotype 12 and Detection of Actinobacillus pleuropneumoniae from Wild Boars.	Sarkozi R, Makrai L, Fodor L.	Pathogens	10.3390/pathogens11050505	2022
	Recent advances in nanogels in veterinary medicine.	Soriano Perez ML, Flores Bracamonte MC, Bellingeri R, Alustiza F, Molina M.	Vet Res	10.1186/s13567-025-01576-y	2025
Phylogeny	Proposal of Actinobacillus pleuropneumoniae serovar 19, and reformulation of previous multiplex PCRs for capsule-specific typing of all known serovars.	Stringer OW, Bosse JT, Lacouture S, Gottschalk M, Fodor L, Angen O, Velazquez E, Penny P, Lei L, Langford PR, Li Y.	Vet Microbiol	10.1016/j.vetmic.2021.109021	2021
Genetics	Whole-Genomic Characterization of Two Different PRRSV-1 Strains Isolated From a Single Pig.	Gong B, Shi J, Xu H, Li C, Xiang L, Guo Z, Li J, Zhang S, Feng Z, Kang H, Zhang X, Song Z, Wang Q, Peng J, Zhou G, Leng C, Zhao K, Tang YD, Liu H, An TQ, Cai X, Tian ZJ, Zhang H.	Transbound Emerg Dis	10.1155/tbed/8260067	2025
Proteome	TurboID screening of ApxI toxin interactants identifies host proteins involved in Actinobacillus pleuropneumoniae-induced apoptosis of immortalized porcine alveolar macrophages.	Hu Y, Jiang C, Zhao Y, Cao H, Ren J, Zeng W, Zhang M, Li Y, He Q, Li W.	Vet Res	10.1186/s13567-023-01194-6	2023
	Bacteria Endocarditis Caused by Mycoplasma hyorhinis in a Juvenile, Immunosuppressed Pig (Sus scrofa domesticus) following Partial Heart Transplantation.	Suk RN, Helke KL, Fitzgerald DC, Hassid M, McVadon D, Taylor CL, Brockbank KGM, Rajab TK, Braxton AM.	Comp Med	10.30802/aalas-cm-23-000090	2024
	Intranasal B5 promotes mucosal defence against Actinobacillus pleuropneumoniae via ameliorating early immunosuppression.	Huang J, Kang W, Yi D, Zhu S, Xiang Y, Liu C, Li H, Dai D, Su J, He J, Liang Z.	Virulence	10.1080/21505594.2024.2316459	2024
Enzymology	Detection of naturally aerosolized Actinobacillus pleuropneumoniae on pig farms by cyclonic air sampling and qPCR.	Watt AE, Browning GF, Markham PF, Marenda MS.	Vet Microbiol	10.1016/j.vetmic.2020.108856	2020
	Biosynthesis of Glycoconjugate Virus-like Particles (VLPs).	Oi KK, Kloter TA, Keys TG.	Methods Mol Biol	10.1007/978-1-0716-0795-4_11	2021
	Local and Systemic T Cell Immunity in Fighting Pig Viral and Bacterial Infections.	Gerner W, Mair KH, Schmidt S.	Annu Rev Anim Biosci	10.1146/annurev-animal-013120-044226	2022
	Draft Genome Sequences of Two Clinical Actinobacillus pleuropneumoniae Serotype 19 Strains from Pigs in Switzerland.	Peterhans S, Stevens MJA, Cernela N, Sidler X, Stephan R, Scherrer S.	Microbiol Resour Announc	10.1128/mra.00588-21	2021
	Molecular survey of porcine respiratory disease complex pathogens in Brazilian wild boars.	da Silva Andrade J, Loiko MR, Schmidt C, Vidaletti MR, Lopes BC, Cerva C, Varela APM, Tochetto C, Maciel ALG, Bertagnolli AC, Rodrigues RO, Roehe PM, Lunge VR, Mayer FQ.	Prev Vet Med	10.1016/j.prevetmed.2022.105698	2022
	A Mini-Fluid Challenge to Predict Fluid Responsiveness in Swine.	Yoshida K.	J Am Assoc Lab Anim Sci	10.30802/aalas-jaalas-24-000026	2025
	Adh Promotes Actinobacillus pleuropneumoniae Survival in Porcine Alveolar Macrophages by Inhibiting CHAC2-Mediated Respiratory Burst and Inflammatory Cytokine Expression.	Zhu J, Zhu R, Jiang H, Li Z, Jiang X, Li F, Zhang F, Feng X, Gu J, Li N, Lei L.	Cells	10.3390/cells12050696	2023
Enzymology	Genetic Diversity of Actinobacillus pleuropneumoniae Serovars in Hungary.	Kardos G, Sarkozi R, Laczko L, Marton S, Makrai L, Banyai K, Fodor L.	Vet Sci	10.3390/vetsci9100511	2022
	A case report and review of the literature on swine hemorrhagic tracheitis syndrome in a Portuguese farm.	Silva F, Garces A, Fontes P, Outor-Monteiro D, Mourao JL, Pires I.	Open Vet J	10.5455/ovj.2024.v14.i3.21	2024
	Pharmacokinetic/pharmacodynamic integration of tilmicosin against Pasteurella multocida in a piglet tissue cage model.	Chen Y, Ji X, Zhang S, Wang W, Zhang H, Ding H.	Front Vet Sci	10.3389/fvets.2023.1260990	2023
	Tea Polyphenols Protects Tracheal Epithelial Tight Junctions in Lung during Actinobacillus pleuropneumoniae Infection via Suppressing TLR-4/MAPK/PKC-MLCK Signaling.	Li X, Liu Z, Gao T, Liu W, Yang K, Guo R, Li C, Tian Y, Wang N, Zhou D, Bei W, Yuan F.	Int J Mol Sci	10.3390/ijms241411842	2023
	Characterization of small plasmids carrying florfenicol resistance gene floR in Actinobacillus pleuropneumoniae and Pasteurella multocida isolates from swine in China.	Yao X, Song Q, Zhu W, Wei J, Shao D, Liu K, Li Z, Qiu Y, Ma Z, Xia L, Li B.	Front Vet Sci	10.3389/fvets.2023.1084491	2023
Enzymology	Phenotype-Specific Semi-Mechanistic Modelling of Florfenicol Time-Kill Curves in G. Parasuis Compared to Other Respiratory Pathogens.	Mead A, Hughes A, Azzariti S, Toutain PL, Pelligand L.	J Vet Pharmacol Ther	10.1111/jvp.13500	2025
	SpyCatcher-SpyTagged ApxIA Toxoid and the Immune-Modulating Yeast Ghost Shells.	Lee S, Han BK, Kim YH, Ahn JY.	J Biomed Nanotechnol	10.1166/jbn.2020.2992	2020
	Identifying DNA methylation types and methylated base positions from bacteria using nanopore sequencing with multi-scale neural network.	Chen Z, Ni P, Wang J.	Bioinformatics	10.1093/bioinformatics/btaf397	2025
	The CpxA/CpxR two-component system mediates regulation of Actinobacillus pleuropneumoniae cold growth.	Yao Q, Xie T, Fu Y, Wan J, Zhang W, Gao X, Huang J, Sun D, Zhang F, Bei W, Lei L, Liu F.	Front Microbiol	10.3389/fmicb.2022.1079390	2022
	Antimicrobial Susceptibility of Glaesserella parasuis to Macrolides and Characterization of erm(T)-Carrying Mobile Elements on Chromosome.	Zhang P, Li C, Shang S, Huang T, Liu J, Ge Q, Liao X, Fang L, Yu Y.	Animals (Basel)	10.3390/ani15020164	2025
Enzymology	Construction and Characterization of Novel Shuttle Expression Vectors for Actinobacillus succinogenes.	Vallejo-Giraldo A, Martinez LM, Flores N, Hernandez-Chavez G, Cueto F, Martinez A, Corona-Gonzalez RI, Gosset G.	Biotechnol Appl Biochem	10.1002/bab.2735	2025
	CpxAR of Actinobacillus pleuropneumoniae Contributes to Heat Stress Response by Repressing Expression of Type IV Pilus Gene apfA.	Liu F, Peng W, Yan K, Huang J, Yuan F, He Q, Chen H, Bei W.	Microbiol Spectr	10.1128/spectrum.02523-22	2022
	Can immunocrit be used as a monitoring tool for swine vaccination and infection studies?	Sagrera M, Sibila M, Martinez-Boixaderas N, Llorens AM, Espigares D, Pastor J, Garza-Moreno L, Segales J.	Porcine Health Manag	10.1186/s40813-024-00380-y	2024
Genetics	Complete genome for Actinobacillus pleuropneumoniae serovar 8 reference strain 405: comparative analysis with draft genomes for different laboratory stock cultures indicates little genetic variation.	Bosse JT, Li Y, Cohen LM, Stegger M, Angen O, Lacouture S, Gottschalk M, Lei L, Koene M, Kuhnert P, Bandara AB, Inzana TJ, Holden MTG, Harris D, Oshota O, Maskell DJ, Tucker AW, Wren BW, Rycroft AN, Langford PR, On Behalf Of The BRaDP T Consortium.	Microb Genom	10.1099/mgen.0.000687	2021
Proteome	Actinobacillus pleuropneumoniae, surface proteins and virulence: a review.	Soto Perezchica MM, Guerrero Barrera AL, Avelar Gonzalez FJ, Quezada Tristan T, Macias Marin O.	Front Vet Sci	10.3389/fvets.2023.1276712	2023
	Evaluation of the Efficacy of a Vaccination Program against Actinobacillus pleuropneumoniae Based on Lung-Scoring at Slaughter.	Sipos W, Cvjetkovic V, Dobrokes B, Sipos S.	Animals (Basel)	10.3390/ani11102778	2021
	Characterization of an atypical Actinobacillus pleuropneumoniae serovar 2 isolate with a rough-type lipopolysaccharide.	To H, Akaike Y, Kon M, Koike F, Shibuya K, Sasakawa C, Nagai S.	J Vet Med Sci	10.1292/jvms.22-0258	2023
Metabolism	The Actinobacillus pleuropneumoniae sulfate-binding protein is required for the acquisition of sulfate and methionine, but is not essential for virulence.	Gao L, Zhang L, Xu H, Zhao F, Ke W, Chen J, Yang J, Qi C, Liu J.	Vet Microbiol	10.1016/j.vetmic.2020.108704	2020
	Differences in pig respiratory tract and peripheral blood immune responses to Actinobacillus pleuropneumoniae.	Bao C, Jiang H, Zhu R, Liu B, Xiao J, Li Z, Chen P, Langford PR, Zhang F, Lei L.	Vet Microbiol	10.1016/j.vetmic.2020.108755	2020
	Identification of stable reference genes in Edwardsiella ictaluri for accurate gene expression analysis.	Lu J, Abdelhamed H, Al-Janabi N, Eissa N, Lawrence M, Karsi A.	PLoS One	10.1371/journal.pone.0309585	2025
	Detection of SXT/R391 integrative conjugative elements carrying tigecycline resistance genes in Shewanella spp. isolated from retail seafood.	Zhang W, Peng K, Liu M, Luo X, Wang Z, Li R.	Antimicrob Agents Chemother	10.1128/aac.01742-24	2025
	First molecular detection of porcine rotavirus B (RVB) in Poland - case study and genome analysis.	Cybulski P, Spiekermeier I, Rybkowska W, Rynkowski J, Stadejek T.	Porcine Health Manag	10.1186/s40813-025-00472-3	2025
Metabolism	Serovar-dependent differences in Hfq-regulated phenotypes in Actinobacillus pleuropneumoniae.	Crispim JS, da Silva TF, Sanches NM, da Silva GC, Pereira MF, Rossi CC, Li Y, Terra VS, Vohra P, Wren BW, Langford PR, Bosse JT, Bazzolli DMS.	Pathog Dis	10.1093/femspd/ftaa066	2020
	Development of a Ready-To-Use Bioluminescence Immunosensor for the One-Step Sensitive Detection of Antibodies Against African Swine Fever Virus.	Zhang Z, Li X, Niu Q, Wang J, Liu Y, Afayibo DJA, Chen W, Yang S, Yin H, Guan G, Yang J.	Microb Biotechnol	10.1111/1751-7915.70253	2025
Enzymology	Comparative Pharmacokinetics of Gentamicin C₁, C_1a and C₂ in Healthy and Infected Piglets.	Kim EY, Kim TW, Awji EG, Lee EB, Park SC.	Antibiotics (Basel)	10.3390/antibiotics13040372	2024
	Enzymatic Synthesis of an Undecorated Capsular Polysaccharide from Campylobacter jejuni.	Xiang DF, Narindoshvili T, Raushel FM.	Biochemistry	10.1021/acs.biochem.5c00314	2025
	Efficacy and safety of intradermal vaccination against porcine circovirus type 2 and Mycoplasma hyopneumoniae under combined exposure field conditions.	Tassis P, Pel S, Floros D, Haar KT, Cao Q, Tsakmakidis I, Papatsiros V, Ntarampa N, Arsenakis I, Tzika ED.	Porcine Health Manag	10.1186/s40813-025-00431-y	2025
	A proposed scheme for the monitoring of antibiotic resistance in veterinary pathogens of food animals in the UK.	Teale C, Borriello P.	Vet Rec	10.1002/vetr.201	2021
	In vivo Pharmacokinetic/pharmacodynamic relationship of florfenicol in combination with doxycycline against Riemerella anatipestifer in ducks and the effect upon resistance development.	Li FL, He CY, Chen HY, Cheng SM, Liu Y, Ding HZ, Zhang HL.	Poult Sci	10.1016/j.psj.2025.104922	2025
	The two-component system CpxA/CpxR is critical for full virulence in Actinobacillus pleuropneumoniae.	Liu F, Yao Q, Huang J, Wan J, Xie T, Gao X, Sun D, Zhang F, Bei W, Lei L.	Front Microbiol	10.3389/fmicb.2022.1029426	2022
	Rational design of a highly active N-glycosyltransferase mutant using fragment replacement approach.	Yang J, Li K, Rong Y, Liu Z, Liu X, Yu Y, Shi W, Kong Y, Chen M.	Eng Microbiol	10.1016/j.engmic.2023.100134	2024
	Pharmacokinetic/Pharmacodynamic Relationships of Tulathromycin Against Actinobacillus pleuropneumoniae in a Porcine Tissue Cage Infection Model.	Yao L, Yang L, Ling Y, Wei Y, Shen X, Ding H.	Front Vet Sci	10.3389/fvets.2022.822432	2022
	Pradofloxacin Minimum Inhibitory Concentration Profiling of Streptococcus suis Isolates: Insights into Antimicrobial Susceptibility in Swine.	Risser J, Tessman R, Bade D, Sahin O, Clavijo MJ, Dhup S, Hoffmann P.	Pathogens	10.3390/pathogens14010088	2025
Genetics	Biological and genomic characterization of a polyvalent phage PSH-1 against multidrug-resistant Salmonella Enteritidis.	Li SH, Wang RY, Zhang JK, Yi KF, Liu JH, Wu H, Yuan L, Zhai YJ, Hu GZ.	BMC Microbiol	10.1186/s12866-024-03489-w	2024
Metabolism	Carbon source utilisation and evaluation of the Biolog system in the identification of Actinobacillus pleuropneumoniae.	Makrai L, Sarkozi R, Fodor L.	Acta Vet Hung	10.1556/004.2019.034	2019
	JMM Profile: Actinobacillus pleuropneumoniae: a major cause of lung disease in pigs but difficult to control and eradicate.	Stringer OW, Li Y, Bosse JT, Langford PR.	J Med Microbiol	10.1099/jmm.0.001483	2022
Pathogenicity	The antimicrobial peptide MPX kills Actinobacillus pleuropneumoniae and reduces its pathogenicity in mice.	Wang L, Zhao X, Zhu C, Zhao Y, Liu S, Xia X, Liu X, Zhang H, Xu Y, Hang B, Sun Y, Chen S, Jiang J, Bai Y, Zhang G, Lei L, Richard LP, Fotina H, Hu J.	Vet Microbiol	10.1016/j.vetmic.2020.108634	2020
	Effect of Anesthesia on Hematologic Parameters of Female Domestic Swine (Sus scrofa domestica).	Carlson MM, Sciurba JD, Saunders KE, Kopanke JH.	J Am Assoc Lab Anim Sci	10.30802/aalas-jaalas-25-018	2025
	Pathogens associated with pleuritic pig lungs at an abattoir in Queensland Australia.	Turni C, Meers J, Parke K, Singh R, Yee S, Templeton J, Mone NK, Blackall PJ, Barnes TS.	Aust Vet J	10.1111/avj.13058	2021
	Clinical utility of nanopore-targeted sequencing for diagnosing and treating pulmonary infectious diseases from bronchoalveolar lavage fluid.	Li G, Sun H, Ye Y, Chen L, Zhang W, Yu S, Li Q, Fan L.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1469440	2025
Genetics	Genomic characteristics, antimicrobial resistance profiles and virulence factors of Gallibacterium anatis isolates from layer chickens in Northern China.	Guo F, Wang D, Wu H, Zhao X, Xu F, Cui Y, Shao Y, Zhang Y, Bu W, Wen T.	BMC Microbiol	10.1186/s12866-025-04440-3	2025
	Diagnostic utility of acute phase proteins and their ability to guide antibiotic usage in pigs, horses, and cattle: a mapping review.	Jakobsen N, Weber NR, Larsen I, Pedersen KS.	Acta Vet Scand	10.1186/s13028-024-00766-6	2024
	Bovine Neutrophil beta-Defensin-5 Provides Protection against Multidrug-Resistant Klebsiella pneumoniae via Regulating Pulmonary Inflammatory Response and Metabolic Response.	Zhu S, Dai D, Li H, Huang J, Kang W, Yang Y, Zhong Y, Xiang Y, Liu C, He J, Liang Z.	Int J Mol Sci	10.3390/ijms251910506	2024
Pathogenicity	N-terminus of flagellin enhances vaccine efficacy against Actinobacillus pleuropneumoniae.	Chuekwon K, Chu CY, Cheng LT.	BMC Vet Res	10.1186/s12917-022-03380-8	2022
	Molecular detection of respiratory coinfections in pig herds with enzootic pneumonia: a survey in Brazil.	Balestrin E, Wolf JM, Wolf LM, Fonseca ASK, Ikuta N, Siqueira FM, Lunge VR.	J Vet Diagn Invest	10.1177/10406387211069552	2022
	A CRISPR/Cas12a-assisted rapid detection platform by biosensing the apxIVA of Actinobacillus pleuropneumoniae.	Luan T, Wang L, Zhao J, Luan H, Zhang Y, Wang C, Langford PR, Liu S, Zhang W, Li G.	Front Microbiol	10.3389/fmicb.2022.928307	2022
	COVID-19 Pandemic Effects on the Activity Levels of Yucatan Mini-Swine (Sus scrofa domesticus).	Barton NE, Ref JE, Cook KE, Baldwin AL, Daugherty SL, Moukabary T, Grijalva A, Kazui S, Mostafizi P, Davis-Gorman GF, Lancaster JJ, Koevary JW, Goldman S.	J Am Assoc Lab Anim Sci	10.30802/aalas-jaalas-24-000017	2024
Metabolism	Comparison of metabolic adaptation and biofilm formation of Actinobacillus pleuropneumoniae field isolates from the upper and lower respiratory tract of swine with respiratory disease.	Aper D, Frombling J, Bagcioglu M, Ehling-Schulz M, Hennig-Pauka I.	Vet Microbiol	10.1016/j.vetmic.2019.108532	2020
	First Molecular Detection of Porcine Cytomegalovirus (PCMV) and Porcine Lymphotropic Herpesvirus (PLHV) in Domestic Pigs in Poland.	Cybulski P, Socha W, Jablonski A, Kondratiuk R, Rybkowska W, Stadejek T, Larska M.	Pathogens	10.3390/pathogens14040396	2025
	Retrospective Analysis of the Detection of Pathogens Associated with the Porcine Respiratory Disease Complex in Routine Diagnostic Samples from Austrian Swine Stocks.	Renzhammer R, Auer A, Loncaric I, Entenfellner A, Dimmel K, Walk K, Rumenapf T, Spergser J, Ladinig A.	Vet Sci	10.3390/vetsci10100601	2023
	Impact of bronchoalveolar lavage from influenza A virus diseased pigs on neutrophil functions and growth of co-infecting pathogenic bacteria	Lassnig S, Hennig-Pauka I, Bonilla M, Morgelin M, Imker R, von Kockritz-Blickwede M, de Buhr N.	Front Immunol		2024
	A Combinatorial Vaccine Containing Inactivated Bacterin and Subunits Provides Protection Against Actinobacillus pleuropneumoniae Infection in Mice and Pigs.	Zhang L, Luo W, Xiong R, Li H, Yao Z, Zhuo W, Zou G, Huang Q, Zhou R.	Front Vet Sci	10.3389/fvets.2022.902497	2022
	Identification of small RNAs associated with RNA chaperone Hfq reveals a new stress response regulator in Actinobacillus pleuropneumoniae.	da Silva GC, Rossi CC, Rosa JN, Sanches NM, Cardoso DL, Li Y, Witney AA, Gould KA, Fontes PP, Callaghan AJ, Bosse JT, Langford PR, Bazzolli DMS.	Front Microbiol	10.3389/fmicb.2022.1017278	2022
	Cross-sectional study of Mycoplasma hyopharyngis, Mycoplasma hyopneumoniae, Mycoplasma hyorhinis and Mycoplasma hyosynoviae in the tonsils of fattening pigs from Central-Eastern Europe.	Nagy EZ, Foldi D, Madzig F, Wehmann E, Orosz A, Kempf A, Buza L, Matyus J, Buza L, Grozner D, Kreizinger Z, Gyuranecz M.	Porcine Health Manag	10.1186/s40813-025-00429-6	2025
	Immunoproteomic characterization of outer membrane vesicles from hyper-vesiculating Actinobacillus pleuropneumoniae.	Antenucci F, Magnowska Z, Nimtz M, Roesch C, Jansch L, Bojesen AM.	Vet Microbiol	10.1016/j.vetmic.2019.07.001	2019
	Synergistic activity of dispersin B and benzoyl peroxide against Cutibacterium acnes/Staphylococcus epidermidis dual-species biofilms.	Kaplan JB, Muzaleva A, Sailer M, Huizinga RB, Kridin K.	PLoS One	10.1371/journal.pone.0320662	2025
	Prospecting potential links between PRRSV infection susceptibility of alveolar macrophages and other respiratory infectious agents present in conventionally reared pigs.	Museau L, Hervet C, Saade G, Menard D, Belloc C, Meurens F, Bertho N.	Vet Immunol Immunopathol	10.1016/j.vetimm.2020.110114	2020
	Polymorphisms in Pattern Recognition Receptor Genes Are Associated with Respiratory Disease Severity in Pig Farms.	Suzuki K, Shinkai H, Yoshioka G, Matsumoto T, Takenouchi T, Tanaka J, Shimizu M, Kitazawa H, Uenishi H.	Animals (Basel)	10.3390/ani12223163	2022
Pathogenicity	The DmsABC S-oxide reductase is an essential component of a novel, hypochlorite-inducible system of extracellular stress defense in Haemophilus influenzae.	Nasreen M, Ellis D, Hosmer J, Essilfie AT, Fantino E, Sly P, McEwan AG, Kappler U.	Front Microbiol	10.3389/fmicb.2024.1359513	2024
	High-dimensional analysis reveals an immune atlas and novel neutrophil clusters in the lungs of model animals with Actinobacillus pleuropneumoniae-induced pneumonia.	Li N, Zhu J, Chen P, Bao C, Wang J, Abdelaal T, Chen D, Zhu S, Wang W, Mao J, Scicluna BP, Koning F, Li F, Lei L.	Vet Res	10.1186/s13567-023-01207-4	2023
	Umbilical outpouchings in pigs - an international survey on fitness for transport, welfare and management.	Hansen ML, Larsen I, Jensen TB, Kristensen CS, Pedersen KS.	Porcine Health Manag	10.1186/s40813-024-00411-8	2025
Metabolism	Porcine circovirus type 2 promotes Actinobacillus pleuropneumoniae survival during coinfection of porcine alveolar macrophages by inhibiting ROS production.	Qi W, Zhu R, Bao C, Xiao J, Liu B, Sun M, Feng X, Gu J, Li Y, Lei L.	Vet Microbiol	10.1016/j.vetmic.2019.04.028	2019
	Antibodies against Actinobacillus pleuropneumoniae, Mycoplasma hyopneumoniae and influenza virus and their relationships with risk factors, clinical signs and lung lesions in pig farms with one-site production systems in Brazil.	Baraldi TG, Cruz NRN, Pereira DA, Galdeano JVB, Gatto IRH, Silva AFD, Panzardi A, Linhares DCL, Mathias LA, de Oliveira LG.	Prev Vet Med	10.1016/j.prevetmed.2019.104748	2019
Phylogeny	Isolation, Identification and Drug Resistance Rates of Bacteria from Pigs in Zhejiang and Surrounding Areas during 2019-2021.	Xu X, Li J, Huang P, Cui X, Li X, Sun J, Huang Y, Ji Q, Wei Q, Bao G, Liu Y.	Vet Sci	10.3390/vetsci10080502	2023
	In silico capsule locus typing for serovar prediction of Actinobacillus pleuropneumoniae.	Li SC, Huang JF, Hung YT, Wu HH, Wang JP, Lin JH, Chen ZW, Hsuan SL.	Microb Genom	10.1099/mgen.0.000780	2022
	Comparative Efficacy in Challenge Dose Models of a Toxin Expressing Whole-Cell Vaccine against Eight Serovars of Actinobacillus pleuropneumoniae in Pigs.	Mortensen P, Toft N, Kiss I, Palya V, Smits H, Tenk M.	Animals (Basel)	10.3390/ani12233244	2022
Metabolism	Identification of genes regulated by the two-component system response regulator NarP of Actinobacillus pleuropneumoniae via DNA-affinity-purified sequencing.	Zhang Q, Huang Q, Fang Q, Li H, Tang H, Zou G, Wang D, Li S, Bei W, Chen H, Li L, Zhou R.	Microbiol Res	10.1016/j.micres.2019.126343	2020
Enzymology	Direct detection of Actinobacillus pleuropneumoniae in swine lungs and tonsils by real-time recombinase polymerase amplification assay.	Li R, Wang J, Liu L, Zhang R, Hao X, Han Q, Wang J, Yuan W.	Mol Cell Probes	10.1016/j.mcp.2019.03.007	2019
	High-Throughput Synthesis and Analysis of Intact Glycoproteins Using SAMDI-MS.	Techner JM, Kightlinger W, Lin L, Hershewe J, Ramesh A, DeLisa MP, Jewett MC, Mrksich M.	Anal Chem	10.1021/acs.analchem.9b04334	2020
Metabolism	Effects of Actinobacillus pleuropneumoniae on barrier function and inflammatory response of pig tracheal epithelial cells.	Bercier P, Gottschalk M, Grenier D.	Pathog Dis	10.1093/femspd/fty079	2019
Enzymology	Comparison of pharmacokinetics of tilmicosin in healthy pigs and pigs experimentally infected with Actinobacillus pleuropneumoniae.	Xiong J, Zhu Q, Yang S, Zhao Y, Cui L, Zhuang F, Qiu Y, Cao J.	N Z Vet J	10.1080/00480169.2019.1633434	2019
	Specific quantitative detection of Streptococcus suis and Actinobacillus pleuropneumoniae in co-infection and mixed biofilms.	Yi L, Jin M, Gao M, Wang H, Fan Q, Grenier D, Sun L, Wang S, Wang Y.	Front Cell Infect Microbiol	10.3389/fcimb.2022.898412	2022
	Efficacy of a Novel PCV2d and Mycoplasma hyopneumoniae Combined Vaccine in Piglets with High and Low Levels of PCV2 Maternally Derived Antibodies at Vaccination.	Sagrera M, Garza-Moreno L, Cobos A, Llorens AM, Huerta E, Perez M, Perez D, Espigares D, Segales J, Sibila M.	Vaccines (Basel)	10.3390/vaccines13101076	2025
Phylogeny	Actinobacillus pleuropneumoniae serotypes in Hungary.	Sarkozi R, Makrai L, Fodor L.	Acta Vet Hung	10.1556/004.2018.031	2018
	alpha-Glycerol monolaurate promotes tight junction proteins expression through PKC/MAPK/ATF-2 signaling pathway.	Dai S, Li C, Li D, Wang H.	Front Nutr	10.3389/fnut.2025.1598991	2025
Pathogenicity	Establishment and comparison of Actinobacillus pleuropneumoniae experimental infection model in mice and piglets.	Bao CT, Xiao JM, Liu BJ, Liu JF, Zhu RN, Jiang P, Li L, Langford PR, Lei LC.	Microb Pathog	10.1016/j.micpath.2019.01.028	2019
	Effect of Feeding Saccharomyces cerevisiae boulardii CNCM I-1079 to Sows and Piglets on Piglets' Immune Response after Vaccination against Actinobacillus pleuropneumoniae.	Bravo de Laguna F, Cabrera C, Gonzalez AB, de Pascual C, Pallares FJ, Chevaux E, Castex M, Saornil D, Lebreton P, Ramis G.	Animals (Basel)	10.3390/ani12192513	2022
	RPSA distribution and expression in tissues and immune cells of pathogen-infected mice.	Liu M, Li N, Guo W, Jia L, Jiang H, Li Z, Wang J, Zhang X, Zhu R, Bao C, Huang J, Lei L.	Microb Pathog	10.1016/j.micpath.2020.104609	2021
Metabolism	A requirement of TolC1 for effective survival, colonization and pathogenicity of Actinobacillus pleuropneumoniae.	Li Y, Cao S, Zhang L, Yuan J, Zhao Q, Wen Y, Wu R, Huang X, Yan Q, Huang Y, Ma X, Han X, Miao C, Wen X.	Microb Pathog	10.1016/j.micpath.2019.103596	2019
Genetics	High incidence and characteristic of PRRSV and resistant bacterial Co-Infection in pig farms.	XiangjinYan, Zeng J, Li X, Zhang Z, Din AU, Zhao K, Zhou Y.	Microb Pathog	10.1016/j.micpath.2020.104536	2020
Phylogeny	Development of selective culture media for efficient isolation of Avibacterium paragallinarum from chickens.	Srednik ME, Shelkamy MMS, Hashish A, R De Macedo N, Sato Y, El-Gazzar MM, Sahin O, Zhang Q.	J Clin Microbiol	10.1128/jcm.00311-25	2025
	An Integrated Analysis of Abattoir Lung Lesion Scores and Antimicrobial Use in Italian Heavy Pig Finishing Farms.	Recchia M, Ghidini S, Romeo C, Scali F, Maisano AM, Guadagno F, De Luca S, Ianieri A, Alborali GL.	Animals (Basel)	10.3390/ani14111621	2024
Pathogenicity	In Vivo Effectiveness of Injectable Antibiotics on the Recovery of Acute Actinobacillus pleuropneumoniae-Infected Pigs.	Papatsiros V, Tzika E, Athanasiou L, Tassis P, Chaintoutis S, Christodoulopoulos G.	Microb Drug Resist	10.1089/mdr.2018.0277	2019
Genetics	A genetic and virulence characterization of Brazilian strains of Mycoplasma hyopneumoniae.	Toledo LT, de Souza LFL, Pereira CER, Polveiro RC, Bressan GC, Yamatogi RS, Jeong KC, Marks FS, Diamantino CA, de Carvalho VHR, Malcher CS, Petri FAM, de Oliveira LG, Moreira MAS, Silva-Junior A.	Front Microbiol	10.3389/fmicb.2023.1280588	2023
	Halicin: A New Horizon in Antibacterial Therapy against Veterinary Pathogens	Wang S, Zhao K, Chen Z, Liu D, Tang S, Sun C, Chen H, Wang Y, Wu C.	Antibiotics (Basel)		2024
	Effect of single parenteral administration of marbofloxacin on bacterial load and selection of resistant Enterobacteriaceae in the fecal microbiota of healthy pigs.	Miyauchi M, El Garch F, Theriault W, Leclerc BG, Lepine E, Giboin H, Rhouma M.	BMC Vet Res	10.1186/s12917-024-04329-9	2024
	Environment-, health-, performance- and welfare-related parameters in pig barns with natural and mechanical ventilation.	Chantziaras I, De Meyer D, Vrielinck L, Van Limbergen T, Pineiro C, Dewulf J, Kyriazakis I, Maes D.	Prev Vet Med	10.1016/j.prevetmed.2020.105150	2020
Pathogenicity	Escherichia coli-Derived Outer Membrane Vesicles Deliver Galactose-1-Phosphate Uridyltransferase and Yield Partial Protection against Actinobacillus pleuropneumoniae in Mice.	Quan K, Zhu Z, Cao S, Zhang F, Miao C, Wen X, Huang X, Wen Y, Wu R, Yan Q, Huang Y, Ma X, Han X, Zhao Q.	J Microbiol Biotechnol	10.4014/jmb.1809.09004	2018
	Transition transferases prime bacterial capsule polymerization.	Litschko C, Di Domenico V, Schulze J, Li S, Ovchinnikova OG, Voskuilen T, Bethe A, Cifuente JO, Marina A, Budde I, Mast TA, Sulewska M, Berger M, Buettner FFR, Lowary TL, Whitfield C, Codee JDC, Schubert M, Guerin ME, Fiebig T.	Nat Chem Biol	10.1038/s41589-024-01664-8	2025
Genetics	Revealing Genomic Insights of the Unexplored Porcine Pathogen Actinobacillus pleuropneumoniae Using Whole Genome Sequencing.	Guitart-Matas J, Gonzalez-Escalona N, Maguire M, Vilaro A, Martinez-Urtaza J, Fraile L, Migura-Garcia L.	Microbiol Spectr	10.1128/spectrum.01185-22	2022
	Antimicrobial Susceptibility Testing of Porcine Bacterial Pathogens: Investigating the Prospect of Testing a Representative Drug for Each Antimicrobial Family.	Vilaro A, Novell E, Enrique-Tarancon V, Balielles J, Migura-Garcia L, Fraile L.	Antibiotics (Basel)	10.3390/antibiotics11050638	2022
	Microbial Primer: Phase variation - survival and adaptability by generation of a diverse population.	Fraser AJ, McMahon FE, Atack JM.	Microbiology (Reading)	10.1099/mic.0.001492	2024
	Identification and Functional Characterization of the Polymerizing Glycosyltransferase Required for the Transfer of d-Ribose to the d-GalfNAc Moiety of the Capsular Polysaccharide of Campylobacter jejuni.	Xiang DF, Narindoshvili T, Raushel FM.	Biochemistry	10.1021/acs.biochem.5c00052	2025
	Explorative Field Study on the Use of Oral Fluids for the Surveillance of Actinobacillus pleuropneumoniae Infections in Fattening Farms by an Apx-Real-Time PCR.	Kleinmans M, Fiebig K, Tabeling R, Swam H, Duivelshof-Crienen A, Ritzmann M, Eddicks M.	Vet Sci	10.3390/vetsci9100552	2022
	Development of a recombinase-aided amplification method combined with lateral flow dipstick assay to detect Porcine circovirus type 2.	Homklinkaew P, Phatthanakunanan S, Jala S, Boonsoongnern A, Lertwatcharasarakul P.	Vet World	10.14202/vetworld.2023.2313-2320	2023
Phylogeny	Molecular detection of ovine gammaherpesvirus 2 in free ranging wild boars (Sus scrofa) from Southern Brazil.	Headley SA, Yasumitsu CY, Dall Agnol AM, de Souza TCGD, da Silva Porto G, Leme RA, Alfieri AF, Alfieri AA.	Braz J Microbiol	10.1007/s42770-024-01302-4	2024
Metabolism	The roles of flp1 and tadD in Actinobacillus pleuropneumoniae pilus biosynthesis and pathogenicity.	Li T, Zhang Q, Wang R, Zhang S, Pei J, Li Y, Li L, Zhou R.	Microb Pathog	10.1016/j.micpath.2018.11.010	2019
	Effect of intervention practices to control the porcine epidemic diarrhea (PED) outbreak during the first epidemic year (2013-2014) on time to absence of clinical signs and the number of dead piglets per sow in Japan.	Furutani A, Sekiguchi S, Sueyoshi M, Sasaki Y.	Prev Vet Med	10.1016/j.prevetmed.2019.104710	2019
Phenotype	Involvement of the Actinobacillus pleuropneumoniae ompW Gene in Confrontation of Environmental Pressure.	Chen X, Shao Z, Wu L, He B, Yang W, Chen J, Jin E, Huang Q, Lei L, Xu J, Li H, Zhang H, Wan Y, Liu W, Zhou R.	Front Vet Sci	10.3389/fvets.2022.846322	2022
Genetics	Antimicrobial Resistance and Genomic Characterization of an Escherichia coli Strain Harboring p0111 and an IncX1-Type Plasmid, Isolated from the Brain of an Ostrich.	Hu J, Zhou J, Wang L, Chen Z, Tan Y, Yin Y, Pei Z, Li C, Bai H, Ma C, Teng L, Feng Y, Li X, Wei Y, Peng H.	Vet Sci	10.3390/vetsci12090793	2025
	Long-chain LPS-based enzyme-linked immunosorbent assay to detect swine herds infected by Actinobacillus pleuropneumoniae serotype 17.	Gottschalk M, Lacouture S, Blackwell T, Bosse J.	Can Vet J		2021
Pathogenicity	Effects of OxyR regulator on oxidative stress, Apx toxin secretion and virulence of Actinobacillus pleuropneumoniae	Guo F, Quan R, Cui Y, Cao X, Wen T, Xu F.	Front Cell Infect Microbiol		2023
	An in vitro study of ApxI from Actinobacillus pleuropneumoniae serotype 10 and induction of NLRP3 inflammasome-dependent cell death.	Hernandez-Cuellar E, Guerrero-Barrera AL, Avelar-Gonzalez FJ, Diaz JM, Chavez-Reyes J, Salazar de Santiago A.	Vet Rec Open	10.1002/vro2.20	2021
	Actinobacillus pleuropneumoniae triggers IL-10 expression in tonsils to mediate colonisation and persistence of infection in pigs.	Mullebner A, Sassu EL, Ladinig A, Frombling J, Miller I, Ehling-Schulz M, Hennig-Pauka I, Duvigneau JC.	Vet Immunol Immunopathol	10.1016/j.vetimm.2018.10.008	2018
Phylogeny	Effects of USP25 knockout on the gut microbial diversity and composition in mice.	Li J, Chen Z, Yan X, Chen Q, Chen C, Liu H, Shen J.	BMC Microbiol	10.1186/s12866-025-04035-y	2025
	Distribution of Actinobacillus pleuropneumoniae (from 2015 to June 2020) and Glaesserella parasuis (from 2017 to June 2020) serotypes isolated from diseased pigs in Quebec.	Lacouture S, Gottschalk M.	Can Vet J		2020
	Development of an Effective Single-Dose PCV2/CSFV Bivalent Subunit Vaccine Against Classical Swine Fever Virus and Porcine Circovirus Type 2.	Chen YC, Chung WB, Chaung HC, Huang YL, Chen CC, Ke GM.	Vaccines (Basel)	10.3390/vaccines13070736	2025
Enzymology	Pharmacokinetics of florfenicol and its metabolite florfenicol amine in the plasma, urine, and feces of fattening male donkeys following single oral administration.	Liu S, Guo Y, Qu H, Dong Y, Zhao S, Fu T, Kang R, Cheng J, Huang S, Zhao L, Ma Q.	Front Vet Sci	10.3389/fvets.2023.1314029	2023
Metabolism	Biological role of Actinobacillus pleuropneumoniae type IV pilus proteins encoded by the apf and pil operons.	Liu F, Peng W, Peng W, Liu T, Zhao H, Yan K, Yuan F, Chen H, Bei W.	Vet Microbiol	10.1016/j.vetmic.2018.08.006	2018
	Göttingen Minipigs as a Model for Assessing the Impact of Drugs on the Gut and Milk Microbiota-A Preliminary Study.	Bencivenni S, Brigidi P, Zannoni A, Ventrella D, Elmi A, Bacci ML, Forni M, D'Amico F, Turroni S.	Nutrients	10.3390/nu16234060	2024
	Investigation of characteristics and classification for swine vertebral osteomyelitis in South Korea.	Han SJ, Kim YH, Lee DK, Im CW, Kim SJ, Han JH.	BMC Vet Res	10.1186/s12917-025-04633-y	2025
Metabolism	The morphology and metabolic changes of Actinobacillus pleuropneumoniae during its growth as a biofilm.	Zhang Q, Peng L, Han W, Chen H, Tang H, Chen X, Langford PR, Huang Q, Zhou R, Li L.	Vet Res	10.1186/s13567-023-01173-x	2023
	Serum Concentrations of Immunoglobulins and Cortisol Around Parturition in Clinically Healthy Sows and Sows with Postpartum Dysgalactia Syndrome (PDS).	Czyzewska-Dors E, Wierzchoslawski K, Pomorska-Mol M.	J Vet Res	10.2478/jvetres-2022-0034	2022
Pathogenicity	Recombinant ApxIV protein enhances protective efficacy against Actinobacillus pleuropneumoniae in mice and pigs.	Wu HC, Yeh PH, Hsueh KJ, Yang WJ, Chu CY.	J Appl Microbiol	10.1111/jam.13726	2018
Pathogenicity	Antimicrobial resistance, biofilm formation and virulence reveal Actinobacillus pleuropneumoniae strains' pathogenicity complexity.	Pereira MF, Rossi CC, Seide LE, Martins Filho S, Dolinski CM, Bazzolli DMS.	Res Vet Sci	10.1016/j.rvsc.2018.05.003	2018
	OseR, a bacterial redox sensor, regulates ergothioneine uptake via a Cys thiol switch, enhancing oxidative stress resistance and virulence.	Zhu X, Wu Y, Yao H, Wu Z.	Redox Biol	10.1016/j.redox.2025.103790	2025
	Spontaneous Lethal Outbreak of Influenza A Virus Infection in Vaccinated Sows on Two Farms Suggesting the Occurrence of Vaccine-Associated Enhanced Respiratory Disease with Eosinophilic Lung Pathology.	Reineking W, Hennig-Pauka I, Schroder L, Honer U, Schreiber E, Geiping L, Lassnig S, Bonilla MC, Hewicker-Trautwein M, de Buhr N.	Viruses	10.3390/v16060955	2024
	New trends in innovative vaccine development against Actinobacillus pleuropneumoniae.	Loera-Muro A, Angulo C.	Vet Microbiol	10.1016/j.vetmic.2018.02.028	2018
	Transcriptomic analysis of porcine PBMCs in response to Actinobacillus pleuropneumoniae reveals the dynamic changes of differentially expressed genes related to immuno-inflammatory responses.	Jiang H, Zhu R, Liu H, Bao C, Liu J, Eltahir A, Langford PR, Sun D, Liu Z, Sun C, Gu J, Han W, Feng X, Lei L.	Antonie Van Leeuwenhoek	10.1007/s10482-018-1126-5	2018
Pathogenicity	Optimal regimens based on PK/PD cutoff evaluation of ceftiofur against Actinobacillus pleuropneumoniae in swine.	Sun D, Mi K, Hao H, Xie S, Chen D, Huang L.	BMC Vet Res	10.1186/s12917-020-02589-9	2020
	Perception about the Major Health Challenges in Different Swine Production Stages in Spain.	Melendez A, Tejedor MT, Mitjana O, Falceto MV, Garza-Moreno L.	Vet Sci	10.3390/vetsci11020084	2024
	Genetic diversity and toxin gene distribution among serovars of Actinobacillus pleuropneumoniae from Australian pigs.	Yee S, Blackall PJ, Turni C.	Aust Vet J	10.1111/avj.12660	2018
	Establishment and validation of a simple and accurate qPCR detection method for Haemophilus parasuis.	Jin H, Xiao X, Wang J, Wang Z, Wei S, Dong C, Zhang Y, Kang C, Sun Y.	Sci Rep	10.1038/s41598-025-92803-1	2025
	ICEAplChn1, a novel SXT/R391 integrative conjugative element (ICE), carrying multiple antibiotic resistance genes in Actinobacillus pleuropneumoniae.	Xu J, Jia H, Cui G, Tong H, Wei J, Shao D, Liu K, Qiu Y, Li B, Ma Z.	Vet Microbiol	10.1016/j.vetmic.2018.05.002	2018
Genetics	Phenotypical and genotypical resistance testing of Pasteurella multocida isolated from different animal species in Austria	Barta L, Stoger A, Polzer D, Ruppitsch W, Schmoll F, Sattler T.	Front Vet Sci		2025
Pathogenicity	Genetically Engineered Bacterial Ghosts as Vaccine Candidates Against Klebsiella pneumoniae Infection.	Dentovskaya SV, Vagaiskaya AS, Trunyakova AS, Kartseva AS, Ivashchenko TA, Gerasimov VN, Platonov ME, Firstova VV, Anisimov AP.	Vaccines (Basel)	10.3390/vaccines13010059	2025
Enzymology	Novel DNA Markers for Identification of Actinobacillus pleuropneumoniae.	Srijuntongsiri G, Mhoowai A, Samngamnim S, Assavacheep P, Bosse JT, Langford PR, Posayapisit N, Leartsakulpanich U, Songsungthong W.	Microbiol Spectr	10.1128/spectrum.01311-21	2022
	Nasal Colonizers from Sows in the Federal District of Brazil Showed a Diverse Phenotypic Resistance Profile.	Rigueira LL, de Sant'Ana FJF, Dallago BSL, de Faria RSA, Rodrigues MM, Obregon-Gutierrez P, Aragon V, Perecmanis S.	Microorganisms	10.3390/microorganisms13061354	2025
	Constitutive expression of antimicrobial peptide PR-39 in transgenic mice significantly enhances resistance to bacterial infection and promotes growth.	Zeng F, Dong R, Zhao C, Liu D, Zheng E, Song C, Wu Z, Li Z.	Transgenic Res	10.1007/s11248-018-0084-z	2018
Pathogenicity	Pharmacokinetic/pharmacodynamic assessment of cefquinome against Actinobacillus Pleuropneumoniae in a piglet tissue cage infection model.	Zhang L, Wu X, Huang Z, Zhang N, Wu Y, Cai Q, Shen X, Ding H.	Vet Microbiol	10.1016/j.vetmic.2018.02.027	2018
	Porcine reproductive and respiratory syndrome developments: An in-depth review of recent findings.	Rimayanti R, Khairullah AR, Lestari TD, Hernawati T, Mulyati S, Utama S, Damayanti R, Moses IB, Yanestria SM, Kusala MKJ, Raissa R, Fauziah I, Wibowo S, Prasetyo A, Awwanah M, Fauzia KA.	Open Vet J	10.5455/ovj.2024.v14.i9.3	2024
	On-Site Dual Detection of Airborne Acinetobacter baumannii and Its Carbapenem-Resistant Gene bla_OXA-23 Using a One-Pot Visual LAMP-CRISPR/Cas12a-Based Platform.	Lu H, Zhang T, Huang W, Zhu J, Qin H, Chen X, Zhao W, Sui G.	Microorganisms	10.3390/microorganisms13050976	2025
	Novel Multiplex PCR Assay and Its Application in Detecting Prevalence and Antibiotic Susceptibility of Porcine Respiratory Bacterial Pathogens in Guangxi, China.	Rao J, Wei X, Li H, Zhang Z, Liu J, Lian M, Cao W, Yuan L, Dou B, Tian Y, Chen H, Li J, Bei W.	Microbiol Spectr	10.1128/spectrum.03971-22	2023
	Streptococcus pluranimalium 2N12 Exerts an Antagonistic Effect Against the Swine Pathogen Actinobacillus pleuropneumoniae by Producing Hydrogen Peroxide.	Vaillancourt K, Frenette M, Gottschalk M, Grenier D.	Front Vet Sci	10.3389/fvets.2021.787241	2021
	Kill Rate and Evaluation of Ex Vivo PK/PD Integration of Cefquinome Against Actinobacillus pleuropneumoniae.	Zhang L, Xie H, Wang H, Ding H, Zhang G, Hu J.	Front Vet Sci	10.3389/fvets.2021.751957	2021
Genetics	Emergence of the zoonotic bacterium Necropsobacter rosorum in nutria Myocastor coypus with implications for wildlife and human health	Laidoudi Y, Davoust B, Lepidi H, Levasseur A.	Sci Rep		2025
	Identification of drug target candidates of the swine pathogen Actinobacillus pleuropneumoniae by construction of protein-protein interaction network.	Li S, Su Z, Zhang C, Xu Z, Chang X, Zhu J, Xiao R, Li L, Zhou R.	Genes Genomics	10.1007/s13258-018-0691-3	2018
	Associations between Pleurisy and the Main Bacterial Pathogens of the Porcine Respiratory Diseases Complex (PRDC).	Petri FAM, Ferreira GC, Arruda LP, Malcher CS, Storino GY, Almeida HMS, Sonalio K, Silva DGD, Oliveira LG.	Animals (Basel)	10.3390/ani13091493	2023
	Impact of nafcillin and diosmin on the attachment, invasion, and stress survival of Salmonella Typhimurium.	Narimisa N, Bostanghadiri N, Khoshbayan A, Gharaghani S, Razavi S, Masjedian Jazi F.	Sci Rep	10.1038/s41598-025-90808-4	2025
	Comparative Minimum Inhibitory and Mutant Prevention Drug Concentrations for Pradofloxacin and Seven Other Antimicrobial Agents Tested against Bovine Isolates of Mannheimia haemolytica and Pasteurella multocida.	Blondeau JM, Fitch SD.	Pathogens	10.3390/pathogens13050399	2024
	Elevated levels of C-reactive protein and pig major acute phase protein in lame gestating sows.	Jakobsen N, Larsen I, Weber NR, Heegaard PMH, Pedersen KS.	Front Vet Sci	10.3389/fvets.2025.1505132	2025
	Challenges and Lessons Learned from a Field Trial on the Understanding of the Porcine Respiratory Disease Complex.	Crisci E, Kick AR, Cortes LM, Byrne JJ, Amaral AF, Love K, Tong H, Zhang J, Gauger PC, Pittman JS, Kaser T.	Vaccines (Basel)	10.3390/vaccines13070740	2025
	Comparative genomics of 26 complete circular genomes of 18 different serotypes of Actinobacillus pleuropneumoniae.	Dona V, Ramette A, Perreten V.	Microb Genom	10.1099/mgen.0.000776	2022
	Update on Actinobacillus pleuropneumoniae-knowledge, gaps and challenges.	Sassu EL, Bosse JT, Tobias TJ, Gottschalk M, Langford PR, Hennig-Pauka I.	Transbound Emerg Dis	10.1111/tbed.12739	2018
	Efficacy of gamithromycin injection administered intramuscularly against bacterial swine respiratory disease.	Xiao T, Yang Y, Zhang Y, Cheng P, Yu H, Liu R, Ishfaq M, Zhang X.	Res Vet Sci	10.1016/j.rvsc.2019.11.006	2020
	Streptococcus equi subspecies zooepidemicus - a case report of sudden death in a German sow farm.	Geiping L, Detlefsen H, Trittmacher S, Baums CG, Bergmann R, Hennig-Pauka I.	Porcine Health Manag	10.1186/s40813-023-00344-8	2023
	Actinobacillus pleuropneumoniae biofilms: Role in pathogenicity and potential impact for vaccination development.	Hathroubi S, Loera-Muro A, Guerrero-Barrera AL, Tremblay YDN, Jacques M.	Anim Health Res Rev	10.1017/s146625231700010x	2018
Metabolism	Actinobacillus pleuropneumoniae culture supernatant antiviral effect against porcine reproductive and respiratory syndrome virus occurs prior to the viral genome replication and transcription through actin depolymerization.	Hernandez Reyes Y, Provost C, Traesel CK, Jacques M, Gagnon CA.	J Med Microbiol	10.1099/jmm.0.000659	2018
	The economic impact of endemic respiratory disease in pigs and related interventions - a systematic review.	Boeters M, Garcia-Morante B, van Schaik G, Segales J, Rushton J, Steeneveld W.	Porcine Health Manag	10.1186/s40813-023-00342-w	2023
	Development of a Corneal and Eye Protection Strategy in Domestic Swine.	Suchyta MA, Gow CK, Lawrence JM, Mardini S.	Comp Med	10.30802/aalas-cm-22-000063	2023
Genetics	Co-cultivation of Lactobacillus acidophilus and Bacillus subtilis mediates the gut-muscle axis affecting pork quality and flavor.	Lin Z, Zhou X, Lu T, An W, Chen S, Li S, Miao H, Han X.	J Anim Sci Biotechnol	10.1186/s40104-025-01229-2	2025
	Recombinant tandem epitope vaccination provides cross protection against Actinobacillus pleuropneumoniae challenge in mice.	Xiao J, Liu J, Bao C, Zhu R, Gu J, Sun C, Feng X, Du C, Han W, Li Y, Lei L.	AMB Express	10.1186/s13568-020-01051-1	2020
	Animal-Based Factors Prior to Infection Predict Histological Disease Outcome in Porcine Reproductive and Respiratory Syndrome Virus- and Actinobacillus pleuropneumoniae-Infected Pigs.	van Dixhoorn IDE, Te Beest DE, Bolhuis JE, Parmentier HK, Kemp B, van Mourik S, Stockhofe-Zurwieden N, van Reenen CG, Rebel JMJ.	Front Vet Sci	10.3389/fvets.2021.742877	2021
	Development and application of an indirect ELISA and nested PCR for the epidemiological analysis of Klebsiella pneumoniae among pigs in China.	Wu Z, Li N, Li Z, Wang J, Liu M, Qi M, Wei S, Wu T, Guo Y, Zhu J, Jiang H, Xue R, Sun C, Feng X, Gu J, Han W, Li F, Lei L.	Front Microbiol	10.3389/fmicb.2023.1329609	2023
	Clinical Efficacy of Two Novel, Differentially Administered (IM, ID) Vaccines against Mycoplasma hyopneumoniae and PCV2 in Swine under Field Conditions.	Sipos W, Sipos S.	Animals (Basel)	10.3390/ani12243467	2022
Phylogeny	Simultaneous detection of antibodies to five Actinobacillus pleuropneumoniae serovars using bead-based multiplex analysis.	Berger SS, Lauritsen KT, Boas U, Lind P, Andresen LO.	J Vet Diagn Invest	10.1177/1040638717719481	2017
Transcriptome	Quinolone Resistance of Actinobacillus pleuropneumoniae Revealed through Genome and Transcriptome Analyses.	Ma X, Zheng B, Wang J, Li G, Cao S, Wen Y, Huang X, Zuo Z, Zhong Z, Gu Y.	Int J Mol Sci	10.3390/ijms221810036	2021
Metabolism	An anti-Propionibacterium acnes antibody shows heterologous resistance to an Actinobacillus pleuropneumoniae infection independent of neutrophils in mice.	Liu JF, Ma QY, Zhu RN, Cheng MJ, Bao CT, Gu JM, Sun CJ, Langford PR, Han WY, Lei LC.	Immunol Res	10.1007/s12026-017-8954-7	2017
	Rationalizing the use of common parameters and technological tools to follow up Mycoplasma hyopneumoniae infections in pigs.	Sonalio K, Boyen F, Devriendt B, Chantziaras I, Beuckelaere L, Biebaut E, Haesebrouck F, Santamarta I, de Oliveira LG, Maes D.	Porcine Health Manag	10.1186/s40813-024-00381-x	2024
	A register-based study on associations between vaccination, antimicrobial use and productivity in conventional Danish finisher pig herds during 2011 to 2014.	Kruse AB, Kristensen CS, Rosenbaum Nielsen L, Alban L.	Prev Vet Med	10.1016/j.prevetmed.2019.01.007	2019
	Actinobacillus pleuropneumoniae Surviving on Environmental Multi-Species Biofilms in Swine Farms.	Loera-Muro A, Ramirez-Castillo FY, Moreno-Flores AC, Martin EM, Avelar-Gonzalez FJ, Guerrero-Barrera AL.	Front Vet Sci	10.3389/fvets.2021.722683	2021
	Porcine beta-Defensin 2 Expressed in Pichia pastoris Alleviates Enterotoxigenic Escherichia coli-Induced Intestinal Injury and Inflammatory Response in Mice.	Wang S, Li H, Huang Y, Zhuo W, Li T, Jiang T, Huang Q, Zhou R.	Animals (Basel)	10.3390/ani15101389	2025
	Characterization of nontypeable Actinobacillus pleuropneumoniae isolates.	To H, Teshima K, Kon M, Yasuda S, Akaike Y, Shibuya K, Nagai S, Sasakawa C.	J Vet Diagn Invest	10.1177/1040638720931469	2020
	Mesomycoplasma hyopneumoniae lipoprotein Mhp390 serves as a plasminogen receptor mediating extracellular matrix degradation and respiratory epithelial cells injury.	Liu W, Ye L, Yang K, Yan X, Gao T, Yuan F, Guo R, Liu Z, Li C, Wu Q, Zhu J, Tian Y, Tang B, Song Q, Zhou D.	Vet Res	10.1186/s13567-025-01551-7	2025
	Characterization of Actinobacillus pleuropneumoniae field strains antigenically related to the 3-6-8-15 group from diseased pigs in Japan and Argentina.	To H, Teshima K, Nagai S, Zielinski GC, Koyama T, Lee J, Bessone FA, Nagano T, Oshima A, Tsutsumi N.	Rev Argent Microbiol	10.1016/j.ram.2017.04.010	2018
	Post-Antibiotic and Post-Antibiotic Sub-Minimum Inhibitory Concentration Effects of Carvacrol against Salmonella Typhimurium.	Boyer E, Galan-Relano A, Romero-Salmoral A, Barraza P, Gomez-Gascon L, Tarradas C, Luque I, de Aguiar FC, Huerta Lorenzo B.	Animals (Basel)	10.3390/ani14182631	2024
Genetics	Geography, niches, and transportation influence bovine respiratory microbiome and health.	Chai J, Liu X, Usdrowski H, Deng F, Li Y, Zhao J.	Front Cell Infect Microbiol	10.3389/fcimb.2022.961644	2022
	Recent Advances in the Development of Metal/Metal Oxide Nanoparticle and Antibiotic Conjugates (MNP-Antibiotics) to Address Antibiotic Resistance: Review and Perspective.	Abdullah, Jamil T, Atif M, Khalid S, Metwally K, Yahya G, Moisa M, Cavalu DS.	Int J Mol Sci	10.3390/ijms25168915	2024
	Development of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) Loads in Pigs and Pig Stables During the Fattening Period.	Pedersen K, Nielsen MW, Fertner ME, Espinosa-Gongora C, Baekbo P.	Vet Sci	10.3390/vetsci11110558	2024
	Assessment of Plasma Tylosin Concentrations: A Comparative Study of Immunoassay, Microbiological Assay, and Liquid Chromatography/Mass Spectrometry.	Lee EB, Sayem SAJ, Lee GY, Kim TW, Hossain MA, Park SC.	Antibiotics (Basel)	10.3390/antibiotics12061023	2023
	Actinobacillus suis isolated from diseased pigs are phylogenetically related but harbour different number of toxin gene copies in their genomes.	Kulathunga DGRS, Fakher AA, Costa MO.	Vet Rec Open	10.1002/vro2.45	2022
Metabolism	Probing peptide substrate specificities of N-glycosyltranferase isoforms from different bacterial species.	Meng Q, Li K, Rong Y, Wu Q, Zhang X, Kong Y, Chen M.	Carbohydr Res	10.1016/j.carres.2018.12.016	2019
	Antimicrobial Stewardship for Respiratory Pathogens in Swine.	Vilaro A, Novell E, Enrique-Tarancon V, Balielles J, Allue E, Fraile L.	Antibiotics (Basel)	10.3390/antibiotics9110727	2020
Metabolism	Identification of four type II toxin-antitoxin systems in Actinobacillus pleuropneumoniae.	Zheng C, Zhao X, Zeng T, Cao M, Xu J, Shi G, Li J, Chen H, Bei W.	FEMS Microbiol Lett	10.1093/femsle/fnx126	2017
	Actinobacillus pleuropneumoniae Eradication with Enrofloxacin May Lead to Dissemination and Long-Term Persistence of Quinolone Resistant Escherichia coli in Pig Herds.	Kaspersen H, Urdahl AM, Grontvedt CA, Gulliksen SM, Tesfamichael B, Slettemeas JS, Norstrom M, Sekse C.	Antibiotics (Basel)	10.3390/antibiotics9120910	2020
Pathogenicity	Outer Membrane Vesicles of Actinobacillus pleuropneumoniae Exert Immunomodulatory Effects on Porcine Alveolar Macrophages.	Zhu Z, Antenucci F, Winther-Larsen HC, Skovgaard K, Bojesen AM.	Microbiol Spectr	10.1128/spectrum.01819-22	2022
	Differential cellular immune response of Galleria mellonella to Actinobacillus pleuropneumoniae.	Arteaga Blanco LA, Crispim JS, Fernandes KM, de Oliveira LL, Pereira MF, Bazzolli DMS, Martins GF.	Cell Tissue Res	10.1007/s00441-017-2653-5	2017
	Polyamine-binding protein PotD2 is required for stress tolerance and virulence in Actinobacillus pleuropneumoniae.	Zhu Z, Zhao Q, Zhao Y, Zhang F, Wen X, Huang X, Wen Y, Wu R, Yan Q, Huang Y, Ma X, Han X, Cao S.	Antonie Van Leeuwenhoek	10.1007/s10482-017-0914-7	2017
	Actinobacillus pleuropneumoniae Interaction With Swine Endothelial Cells.	Plasencia-Munoz B, Avelar-Gonzalez FJ, De la Garza M, Jacques M, Moreno-Flores A, Guerrero-Barrera AL.	Front Vet Sci	10.3389/fvets.2020.569370	2020
Enzymology	Comparative Study on Pharmacokinetics of Four Long-Acting Injectable Formulations of Enrofloxacin in Pigs.	Ahmad SU, Sun J, Cheng F, Li B, Arbab S, Zhou X, Zhang J.	Front Vet Sci	10.3389/fvets.2020.604628	2020
Pathogenicity	Antibacterial activity against porcine respiratory bacterial pathogens and in vitro biocompatibility of essential oils.	LeBel G, Vaillancourt K, Bercier P, Grenier D.	Arch Microbiol	10.1007/s00203-019-01655-7	2019
	Understanding prokaryotic adaptation through advanced DNA methylation detection techniques.	Chen Z, Ong CT, Ross EM.	ISME J	10.1093/ismejo/wraf143	2025
Metabolism	Enhancement of Apx Toxin Production in Actinobacillus pleuropneumoniae Serotypes 1, 2, and 5 by Optimizing Culture Condition.	Dao HT, Do VT, Truong QL, Hahn TW.	J Microbiol Biotechnol	10.4014/jmb.1912.12042	2020
	De novo identification of bacterial antigens of a clinical isolate by combining use of proteosurfaceomics, secretomics, and BacScan technologies.	Yang J, Zhang X, Dong J, Zhang Q, Sun E, Chen C, Miao Z, Zheng Y, Zhang N, Tao P.	Front Immunol	10.3389/fimmu.2023.1274027	2023
Enzymology	Tilmicosin enteric granules and premix to pigs: Antimicrobial susceptibility testing and comparative pharmacokinetics.	Xiong J, Zhu Q, Zhao Y, Yang S, Cao J, Qiu Y.	J Vet Pharmacol Ther	10.1111/jvp.12753	2019
	Design of a New Vaccine Prototype against Porcine Circovirus Type 2 (PCV2), M. hyopneumoniae and M. hyorhinis Based on Multiple Antigens Microencapsulation with Sulfated Chitosan.	Arrieta-Mendoza D, Garces B, Hidalgo AA, Neira V, Ramirez G, Neira-Carrillo A, Bucarey SA.	Vaccines (Basel)	10.3390/vaccines12050550	2024
Pathogenicity	Serum Amyloid A: A Double-Edged Sword in Health and Disease.	Ji A, Meredith LW, Shridas P.	Int J Mol Sci	10.3390/ijms26104528	2025
	Antimicrobial Susceptibility Pattern of Porcine Respiratory Bacteria in Spain.	Vilaro A, Novell E, Enrique-Tarancon V, Balielles J, Vilalta C, Martinez S, Fraile Sauce LJ.	Antibiotics (Basel)	10.3390/antibiotics9070402	2020
	In vivo pharmacokinetic and pharmacodynamic study and cutoff of florfenicol against Riemerella anatipestifer in ducks.	Zhang HL, Li FL, Chen HY, Qin DM, Sun SJ, Zhang MM, Ding HZ, Liu Y.	Poult Sci	10.1016/j.psj.2024.104635	2025
	Construction and Application of MALDI-TOF Mass Spectrometry for the Detection of Haemophilus parasuis.	Wang X, Xu F, Ning K, Shen L, Qi X, Wang J.	Biomed Res Int	10.1155/2021/5588855	2021
Enzymology	Tilmicosin- and florfenicol-loaded hydrogenated castor oil-solid lipid nanoparticles to pigs: Combined antibacterial activities and pharmacokinetics.	Ling Z, Yonghong L, Junfeng L, Li Z, Xianqiang L.	J Vet Pharmacol Ther	10.1111/jvp.12465	2018
	Interleukin-17 producing cells in swine induced by microbiota during the early postnatal period - a brief research report.	Stepanova H, Scheirichova M, Matiasovic J, Hlavova K, Sinkora M, Stepanova K, Faldyna M.	Front Immunol	10.3389/fimmu.2023.1214444	2023
	Dynamics of PCV2 and PCV3 in the Serum and Oral Fluids of Pigs After PCV2 Vaccination in a Commercial Farm.	Hernandez J, Henao-Diaz A, Resendiz-Sandoval M, Cota-Valdez A, Mata-Haro V, Gimenez-Lirola LG.	Vaccines (Basel)	10.3390/vaccines12121318	2024
	TolC2 is required for the resistance, colonization and virulence of Actinobacillus pleuropneumoniae.	Li Y, Cao S, Zhang L, Yuan J, Yang Y, Zhu Z, Wen Y, Wu R, Zhao Q, Huang X, Yan Q, Huang Y, Ma X, Wen X.	J Med Microbiol	10.1099/jmm.0.000544	2017
	Impact of porcine respiratory disease complex on carcass weight and meatiness: quantitative insights from a mixed-model analysis.	Przyborowska P, Lewko-Wojtowicz R, Cybulski P, Maes D, Tobolski D.	BMC Vet Res	10.1186/s12917-024-04410-3	2024
	Effects of antibiotic and disinfectant exposure on the mouse gut microbiome and immune function.	Xu W-B, Wang Y-F, Meng S-Y, Zhang X-T, Wang Y-R, Liu Z-Y.	Microbiol Spectr	10.1128/spectrum.00611-24	2024
Pathogenicity	Activity of florfenicol for Actinobacillus pleuropneumoniae and Pasteurella multocida using standardised versus non-standardised methodology.	Dorey L, Hobson S, Lees P.	Vet J	10.1016/j.tvjl.2016.11.004	2016
	Evaluating the Global Distribution and Characteristics of Research Studies Focusing on Swine Farm Biosecurity: A Scoping Review.	Agrawal I, Kerby EE, Varga C.	Transbound Emerg Dis	10.1155/2024/6497633	2024
Pathogenicity	Factors influencing the potency of marbofloxacin for pig pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida.	Dorey L, Hobson S, Lees P.	Res Vet Sci	10.1016/j.rvsc.2016.11.011	2017
	Type IV minor pilin ComN predicted the USS-receptor in Pasteurellaceae.	Helsem SA, Alfsnes K, Frye SA, Lovestad AH, Ambur OH.	Front Microbiol	10.3389/fmicb.2025.1647523	2025
	Scoring of swine lung images: a comparison between a computer vision system and human evaluators.	Valeris-Chacin R, Garcia-Morante B, Sibila M, Canturri A, Ballara Rodriguez I, Bernal Orozco I, Jorda Casadevall R, Munoz P, Pieters M.	Vet Res	10.1186/s13567-024-01432-5	2025
	Anti-Ascaris suum IgG antibodies in fattening pigs with different respiratory conditions.	Lassen B, Geldhof P, Halli O, Vlaminck J, Oliviero C, Orro T, Heinonen M.	Vet Parasitol	10.1016/j.vetpar.2018.12.005	2019
	First molecular detection of Brachyspira suanatina on pig farms in Poland.	Cybulski P, Strutzberg-Minder K, Michalik E, Kondratiuk R, Jablonski A.	J Vet Res	10.2478/jvetres-2023-0038	2023
	The Metabolic Adaptation in Response to Nitrate Is Critical for Actinobacillus pleuropneumoniae Growth and Pathogenicity under the Regulation of NarQ/P.	Zhang Q, Tang H, Yan C, Han W, Peng L, Xu J, Chen X, Langford PR, Bei W, Huang Q, Zhou R, Li L.	Infect Immun	10.1128/iai.00239-22	2022
	Lungworms (Metastrongylus spp.) demonstrated in domestic pigs with respiratory disease: was there a clinical relevance?	Wallgren P, Pettersson E.	Porcine Health Manag	10.1186/s40813-022-00258-x	2022
Pathogenicity	Potency of marbofloxacin for pig pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida: Comparison of growth media.	Dorey L, Hobson S, Lees P.	Res Vet Sci	10.1016/j.rvsc.2016.11.001	2017
	Rapid Detection of Actinobacillus pleuropneumoniae From Clinical Samples Using Recombinase Polymerase Amplification.	Stringer OW, Li Y, Bosse JT, Forrest MS, Hernandez-Garcia J, Tucker AW, Nunes T, Costa F, Mortensen P, Velazquez E, Penny P, Rodriguez-Manzano J, Georgiou P, Langford PR.	Front Vet Sci	10.3389/fvets.2022.805382	2022
	Co-infections of respiratory pathogens and gastrointestinal parasites in smallholder pig production systems in Uganda.	Oba P, Wieland B, Mwiine FN, Erume J, Dione MM.	Parasitol Res	10.1007/s00436-023-07797-4	2023
	Dynamic immune response characteristics of piglets infected with Actinobacillus pleuropneumoniae through omic.	Zhu R, Jiang H, Wang J, Bao C, Liu H, Li F, Lei L.	AMB Express	10.1186/s13568-021-01336-z	2021
	Causes of swine polyserositis in a high-density breeding area in Italy.	Salogni C, Lazzaro M, Giovannini S, Vitale N, Boniotti MB, Pozzi P, Pasquali P, Alborali GL.	J Vet Diagn Invest	10.1177/1040638720928973	2020
	Development of a detection chip for major pathogenic drug-resistant genes and drug targets in bovine respiratory system diseases.	Qi J, Li P, Yan Y, Li G, Kong L.	Open Life Sci	10.1515/biol-2022-0778	2024
	Nucleotide sequence analysis of a DNA region involved in capsular polysaccharide biosynthesis reveals the molecular basis of the nontypeability of two Actinobacillus pleuropneumoniae isolates.	Ito H, Ogawa T, Fukamizu D, Morinaga Y, Kusumoto M.	J Vet Diagn Invest	10.1177/1040638716656026	2016
Pathogenicity	Thymol kills bacteria, reduces biofilm formation, and protects mice against a fatal infection of Actinobacillus pleuropneumoniae strain L20.	Wang L, Zhao X, Zhu C, Xia X, Qin W, Li M, Wang T, Chen S, Xu Y, Hang B, Sun Y, Jiang J, Richard LP, Lei L, Zhang G, Hu J.	Vet Microbiol	10.1016/j.vetmic.2017.02.021	2017
	Kinetics of single and dual infection of pigs with swine influenza virus and Actinobacillus pleuropneumoniae.	Pomorska-Mol M, Dors A, Kwit K, Kowalczyk A, Stasiak E, Pejsak Z.	Vet Microbiol	10.1016/j.vetmic.2017.01.011	2017
	Field study on the utility of fluid obtained from testicles as a sample for detecting antibodies to selected swine pathogens.	Augustyniak A, Czyzewska-Dors E, Pomorska-Mol M.	Sci Rep	10.1038/s41598-025-05380-8	2025
	Identification of Nonsynonymous SNPs in Immune-Related Genes Associated with Pneumonia Severity in Pigs.	Shinkai H, Suzuki K, Itoh T, Yoshioka G, Takenouchi T, Kitazawa H, Uenishi H.	Genes (Basel)	10.3390/genes15081103	2024
Metabolism	Study of biological activity and targeted distribution of catesbeianalectin in mouse tissue.	Zhao RL, Zhu L, Liu MY, Jin TM, Ma JF, Hu Y, Wang X, Qin SY, Chen JB.	Pak J Pharm Sci		2018
Enzymology	Bayesian population pharmacokinetic modeling of florfenicol in pigs after intravenous and intramuscular administration.	Liu Z, Rong T, Zeng D, Shen X, Ma X, Zeng Z.	J Vet Pharmacol Ther	10.1111/jvp.12677	2018
	Evaluation of carcass quality, body and pulmonary lesions detected at the abattoir in heavy pigs subjected or not to tail docking.	Amatucci L, Luise D, Luppi A, Virdis S, Prosperi A, Cirelli A, Bosco C, Trevisi P.	Porcine Health Manag	10.1186/s40813-022-00297-4	2023
	Apa2H1, the first head domain of Apa2 trimeric autotransporter adhesin, activates mouse bone marrow-derived dendritic cells and immunization with Apa2H1 protects against Actinobacillus pleuropneumoniae infection.	Qin W, Wang L, Zhai R, Ma Q, Liu J, Bao C, Sun D, Zhang H, Sun C, Feng X, Gu J, Du C, Han W, Langford PR, Lei L.	Mol Immunol	10.1016/j.molimm.2016.12.004	2017
	Immunogenicity of Bacillus Calmette-Guérin in pigs: potential as a translational model of non-specific effects of BCG.	Jensen KJ, Hansen MS, Skovgaard K, Svensson E, Larsen LE, Heegaard PMH, Benn CS, Jungersen G.	Front Immunol	10.3389/fimmu.2023.1219006	2023
	An In-House ELISA for Anti-Porcine Circovirus Type 2d (PCV2d) IgG: Analytical Validation and Serological Correlation.	Park GS, Seo BJ, Kwon WJ, Seok YL, Lee HJ, Lee SH, Kim M, Lee M, Chae C, Kim C.	Vaccines (Basel)	10.3390/vaccines13060657	2025
	Complete Genome Sequence of Actinobacillus pleuropneumoniae Strain KL 16 (Serotype 1).	Park BS, Han J, Shin DJ, Jeong YJ, Lee N.	Genome Announc	10.1128/genomea.01025-17	2017
	Genetic and antigenic characteristics of ApxIIA and ApxIIIA from Actinobacillus pleuropneumoniae serovars 2, 3, 4, 6, 8 and 15.	To H, Nagai S, Iwata A, Koyama T, Oshima A, Tsutsumi N.	Microbiol Immunol	10.1111/1348-0421.12388	2016
Pathogenicity	Applying definitions for multidrug resistance, extensive drug resistance and pandrug resistance to clinically significant livestock and companion animal bacterial pathogens.	Sweeney MT, Lubbers BV, Schwarz S, Watts JL.	J Antimicrob Chemother	10.1093/jac/dky043	2018
Metabolism	Detection of PR-39, a porcine host defence peptide, in different cell sub-linages in pigs infected with Actinobacillus pleuropneumoniae.	Gabner S, Egerbacher M, Gasse H, Hewicker-Trautwein M, Holtig D, Waldmann KH, Blecha F, Saalmuller A, Hennig-Pauka I.	Histol Histopathol	10.14670/hh-11-869	2017
	Seasonal Variation in Prevalence of Mycoplasma hyopneumoniae and Other Respiratory Pathogens in Peri-Weaned, Post-Weaned, and Fattening Pigs with Clinical Signs of Respiratory Diseases in Belgian and Dutch Pig Herds, Using a Tracheobronchial Swab Sampling Technique, and Their Associations with Local Weather Conditions.	Vangroenweghe FACJ, Thas O.	Pathogens	10.3390/pathogens10091202	2021
Metabolism	Exposure to benzylpenicillin after different dosage regimens in growing pigs.	Sjolund M, Ekstrand C, Wallgren P, Bondesson U, Pringle M, Bengtsson B.	Acta Vet Scand	10.1186/s13028-020-00552-0	2020
	Development of a Triplex qPCR Assay Based on the TaqMan Probe for the Detection of Haemophilus parasuis, Streptococcus suis Serotype 2 and Pasteurella multocida.	Li K, Zhang Y, Luo T, Li C, Yu H, Wang W, Zhang H, Chen H, Xia C, Gao C.	Microorganisms	10.3390/microorganisms12102017	2024
	Rationally designed mariner vectors for functional genomic analysis of Actinobacillus pleuropneumoniae and other Pasteurellaceae species by transposon-directed insertion-site sequencing (TraDIS).	Bosse JT, Li Y, Leanse LG, Zhou L, Chaudhuri RR, Peters SE, Wang J, Maglennon GA, Holden MTG, Maskell DJ, Tucker AW, Wren BW, Rycroft AN, Langford PR, BRaDP1T consortium.	Anim Dis	10.1186/s44149-021-00026-4	2021
	Impact of Actinobacillus pleuropneumoniae biofilm mode of growth on the lipid A structures and stimulation of immune cells.	Hathroubi S, Beaudry F, Provost C, Martelet L, Segura M, Gagnon CA, Jacques M.	Innate Immun	10.1177/1753425916649676	2016
Pathogenicity	Antimicrobial resistance genes in Actinobacillus pleuropneumoniae, Haemophilus parasuis and Pasteurella multocida isolated from Australian pigs.	Dayao D, Gibson JS, Blackall PJ, Turni C.	Aust Vet J	10.1111/avj.12458	2016
Metabolism	IFN-gamma^-/- Mice Resist Actinobacillus pleuropneumoniae Infection by Promoting Early Lung IL-18 Release and PMN-I Accumulation.	Bao C, Liu B, Zhu R, Xiao J, Li Z, Jiang H, Wang B, Langford PR, Fei R, Li N, Lei L.	Infect Immun	10.1128/iai.00069-21	2021
	Co-infection analysis of bacterial and viral respiratory pathogens from clinically healthy swine in Eastern China.	Zhu H, Chang X, Zhou J, Wang D, Zhou J, Fan B, Ni Y, Yin J, Lv L, Zhao Y, He K, Li B.	Vet Med Sci	10.1002/vms3.533	2021
	In vitro Mixed Biofilm of Streptococcus suis and Actinobacillus pleuropneumoniae Impacts Antibiotic Susceptibility and Modulates Virulence Factor Gene Expression.	Wang Y, Gong S, Dong X, Li J, Grenier D, Yi L.	Front Microbiol	10.3389/fmicb.2020.00507	2020
	The CueR-regulated transporters CopA and CusFABC coordinate copper detoxification in Vibrio parahaemolyticus.	Zheng C, Zhai Y, Wang M, Xu Z, Zhang Y, Zhou X, Chen X, Jiao X.	Virulence	10.1080/21505594.2025.2545557	2025
Metabolism	Be Aware of Immunogenic But not Protective Antigens: The Actinobacillus pleuropneumoniae PalA as an Example.	Liu C, Cao Y, Yang J, Zhao H, Zahid KR, Zhao J, Qi C, Liu J.	Protein Pept Lett	10.2174/0929866524666170822121558	2017
	Metabolic Footprint of Treponema phagedenis and Treponema pedis Reveals Potential Interaction Towards Community Succession and Pathogenesis in Bovine Digital Dermatitis.	Espiritu HM, Valete EJP, Mamuad LL, Jung M, Paik MJ, Lee SS, Cho YI.	Pathogens	10.3390/pathogens13090796	2024
	Rapid Detection and Typing of Actinobacillus pleuropneumoniae Serovars Directly From Clinical Samples: Combining FTA^® Card Technology With Multiplex PCR.	Stringer OW, Bosse JT, Lacouture S, Gottschalk M, Fodor L, Angen O, Velazquez E, Penny P, Lei L, Langford PR, Li Y.	Front Vet Sci	10.3389/fvets.2021.728660	2021
	Design and Characterization of a Novel Tool for the Antigenic Enrichment of Actinobacillus pleuropneumoniae Outer Membrane.	Antenucci F, Ovsepian A, Wrobel A, Winther-Larsen HC, Bojesen AM.	Pathogens	10.3390/pathogens9121014	2020
	Effect of Live and Fragmented Saccharomyces cerevisiae in the Feed of Pigs Challenged with Mycoplasma hyopneumoniae.	Vega-Munguia G, Vargas Sanchez A, Camacho-Medina JE, Suarez-Velez L, Barcenas-Morales G, Quintar Guerrero D, Ciprian-Carrasco A, Mendoza Elvira S.	Pathogens	10.3390/pathogens13040322	2024
Transcriptome	Vertebral fracture due to Actinobacillus pleuropneumoniae osteomyelitis in a weaner.	Giebels F, Geissbuhler U, Oevermann A, Grahofer A, Olias P, Kuhnert P, Maiolini A, Stein VM.	BMC Vet Res	10.1186/s12917-020-02656-1	2020
Enzymology	A loop-mediated isothermal amplification procedure targeting the sodA gene for rapid and specific identification of Gallibacterium anatis.	Stepien-Pysniak D, Kosikowska U, Hauschild T, Burzynski A, Wilczynski J, Kolinska A, Nowaczek A, Marek A.	Poult Sci	10.3382/ps/pex420	2018
	Determination of Tiamulin Concentration in Sow Milk and in Sera of Suckling Piglets.	Cybulski P, Gajda A, Bilecka M, Jablonski A.	Molecules	10.3390/molecules28196940	2023
	Comparative Analysis of the Upper Respiratory Bacterial Communities of Pigs with or without Respiratory Clinical Signs: From Weaning to Finishing Phase.	Rampelotto PH, Dos Santos ACR, Muterle Varela AP, Takeuti KL, Loiko MR, Mayer FQ, Roehe PM.	Biology (Basel)	10.3390/biology11081111	2022
	Identification of a proposed new serovar of Actinobacillus Pleuropneumoniae: Serovar 16.	Sarkozi R, Makrai L, Fodor L.	Acta Vet Hung	10.1556/004.2015.041	2015
	Efficacy of an herb and essential oil-based phytobiotic blend and its interaction with an antibiotic on intestinal health, growth performance, and carcass characteristics in growing pigs.	Sung JY, Parnsen W, Garavito-Duarte Y, Kim SW.	J Anim Sci	10.1093/jas/skaf370	2025
Phylogeny	The developing pig respiratory microbiome harbors strains antagonistic to common respiratory pathogens.	Vlasblom AA, Duim B, Patel S, Luiken REC, Crespo-Piazuelo D, Eckenberger J, Huseyin CE, Lawlor PG, Elend C, Wagenaar JA, Claesson MJ, Zomer AL.	mSystems	10.1128/msystems.00626-24	2024
	Production and immunogenicity of Actinobacillus pleuropneumoniae ApxIIA protein in transgenic rice callus.	Kim MY, Kim TG, Yang MS.	Protein Expr Purif	10.1016/j.pep.2016.05.010	2017
	Molecular serotyping and antimicrobial resistance profiles of Actinobacillus pleuropneumoniae isolated from pigs in South Korea.	Kim B, Hur J, Lee JY, Choi Y, Lee JH.	Vet Q	10.1080/01652176.2016.1155241	2016
	Glaesserella parasuis serotype 4 exploits fibronectin via RlpA for tracheal colonization following porcine circovirus type 2 infection.	Guo M, Li Y, Tang J, Wang Q, Wang Q, Zhou H, Lin H, Ma Z, Fan H.	PLoS Pathog	10.1371/journal.ppat.1012513	2024
Metabolism	N-Glycosyltransferase from Aggregatibacter aphrophilus synthesizes glycopeptides with relaxed nucleotide-activated sugar donor selectivity.	Kong Y, Li J, Hu X, Wang Y, Meng Q, Gu G, Wang PG, Chen M.	Carbohydr Res	10.1016/j.carres.2018.03.008	2018
Genetics	Whole Genome Sequencing and Pan-Genomic Analysis of Multidrug-Resistant Vibrio cholerae VC01 Isolated from a Clinical Sample.	Mevada V, Patel R, Dudhagara P, Chaudhari R, Vohra M, Khan V, J H Shyu D, Chen YY, Zala D.	Microorganisms	10.3390/microorganisms11082030	2023
	The absence of luxS reduces the invasion of Avibacterium paragallinarum but is not essential for virulence.	Li D, Huo C, Li G, Zhu M, Xu F, Qiao J, Sun H.	Front Vet Sci	10.3389/fvets.2024.1427966	2024
	Rapid detection of Mycoplasma hyopneumoniae by recombinase-aided amplification combined with the CRISPR/Cas12a system.	Li K, Luo T, Zhang Y, Li C, Chen H, Xia C, Gao C.	Front Cell Infect Microbiol	10.3389/fcimb.2024.1469558	2024
	Evaluation of Efficacy of 2 Extended-release Bupivacaine Products in a Porcine Model of Incisional Pain.	Yang P, Yang S, Durham LB, Lester PA, Myers DD.	J Am Assoc Lab Anim Sci	10.30802/aalas-jaalas-23-000106	2024
	Rapid Visual Detection of Glaesserella parasuis with a Real-Time Recombinase-Aided Amplification Assay.	Kang H, Chen D, Yang X, Jiang R, Song C, Zhang Y, Zhou L, Ge X, Han J, Guo X, Yang H.	Transbound Emerg Dis	10.1155/2023/9993586	2023
	Coinfections and Phenotypic Antimicrobial Resistance in Actinobacillus pleuropneumoniae Strains Isolated From Diseased Swine in North Western Germany-Temporal Patterns in Samples From Routine Laboratory Practice From 2006 to 2020.	Hennig-Pauka I, Hartmann M, Merkel J, Kreienbrock L.	Front Vet Sci	10.3389/fvets.2021.802570	2021
	The challenge of detecting herds sub-clinically infected with Actinobacillus pleuropneumoniae.	Gottschalk M.	Vet J	10.1016/j.tvjl.2015.06.016	2015
	Effect of Vaccination against Glässer's Disease in a Farm Suffering from Polyserositis in Weaned Pigs.	Hattab J, Marruchella G, Trachtman AR, Gabrielli L, Bernabo N, Mosca F, Tiscar PG.	Vet Sci	10.3390/vetsci9120691	2022
	B cell cross-epitope of Propionibacterium acnes and Actinobacillus pleuropneumonia selected by phage display library can efficiently protect from Actinobacillus pleuropneumonia infection.	Liu J, Ma Q, Yang F, Zhu R, Gu J, Sun C, Feng X, Du C, Langford PR, Han W, Yang J, Lei L.	Vet Microbiol	10.1016/j.vetmic.2017.04.026	2017
Genetics	Comparative analysis of antimicrobial resistance and genetic diversity of Bordetella bronchiseptica isolates obtained from swine within the United States.	Nicholson TL, Shore SM.	Front Microbiol	10.3389/fmicb.2024.1501373	2024
	Quantification of major bacterial pathogens in liver abscesses and matched ruminal and colonic epithelial tissues of feedlot cattle.	Abbasi M, Deters A, Salih H, Wilson RA, Schneid KN, Shi X, George LA, Bai J, Amachawadi RG, Woerner DR, Samuelson KL, Lawrence TE, Nagaraja TG.	Microbiol Spectr	10.1128/spectrum.01888-25	2025
	Gastric ulcers in finishing pigs: the evaluation of selected non-dietary risk factors and impact on production performance.	Cybulski P, Wozniak A, Larska M, Jablonski A, Stadejek T.	Porcine Health Manag	10.1186/s40813-024-00362-0	2024
	Identification of Actinobacillus pleuropneumoniae Genes Preferentially Expressed During Infection Using In Vivo-Induced Antigen Technology (IVIAT).	Zhang F, Zhang Y, Wen X, Huang X, Wen Y, Wu R, Yan Q, Huang Y, Ma X, Zhao Q, Cao S.	J Microbiol Biotechnol	10.4014/jmb.1504.04007	2015
Metabolism	The Lon protease homologue LonA, not LonC, contributes to the stress tolerance and biofilm formation of Actinobacillus pleuropneumoniae.	Xie F, Li G, Zhang Y, Zhou L, Liu S, Liu S, Wang C.	Microb Pathog	10.1016/j.micpath.2016.01.009	2016
Metabolism	Outer membrane lipoprotein VacJ is required for the membrane integrity, serum resistance and biofilm formation of Actinobacillus pleuropneumoniae.	Xie F, Li G, Zhang W, Zhang Y, Zhou L, Liu S, Liu S, Wang C.	Vet Microbiol	10.1016/j.vetmic.2015.11.021	2016
	Mix-and-Match System for the Enzymatic Synthesis of Enantiopure Glycerol-3-Phosphate-Containing Capsule Polymer Backbones from Actinobacillus pleuropneumoniae, Neisseria meningitidis, and Bibersteinia trehalosi.	Litschko C, Budde I, Berger M, Bethe A, Schulze J, Alcala Orozco EA, Mahour R, Goettig P, Fuhring JI, Rexer T, Gerardy-Schahn R, Schubert M, Fiebig T.	mBio	10.1128/mbio.00897-21	2021
	Angiotensin II Blood Serum Levels in Piglets, after Intra-Dermal or Intra-Muscular Vaccination against PRRSV.	Maragkakis G, Athanasiou LV, Korou LM, Chaintoutis SC, Dovas C, Perrea DN, Papakonstantinou G, Christodoulopoulos G, Maes D, Papatsiros VG.	Vet Sci	10.3390/vetsci9090496	2022
	Associations between manure pumping out of the site and exposure to nearby manure applications with the incidence of porcine reproductive and respiratory syndrome virus and porcine epidemic diarrhea virus outbreaks in wean-to-market pig populations in the Midwestern United States.	Serafini Poeta Silva AP, Amorim Moura C, Johansen N, Moraes D, Romero Nicolino R, Magalhaes ES, Rupasinghe K, Jayaraman S, Rademacher C, Trevisan G, Linhares DCL, Silva GS.	Front Vet Sci	10.3389/fvets.2025.1595313	2025
Enzymology	Characterization of bifunctional L-glutathione synthetases from Actinobacillus pleuropneumoniae and Actinobacillus succinogenes for efficient glutathione biosynthesis.	Yang J, Li W, Wang D, Wu H, Wu H, Li Z, Ye Q.	Appl Microbiol Biotechnol	10.1007/s00253-016-7437-4	2016
	TLR Agonist Immunoadjuvants Provide Effective Protection Against PCV2 and PRV Infections in a Bivalent Subunit Vaccine for PCV2 and PRV.	Yu F, Xiang W, Ou W, Li Y, Shu X, Li X.	Vet Sci	10.3390/vetsci12010025	2025
	Murine Thigh Microdialysis to Evaluate the Pharmacokinetic/Pharmacodynamic Integration of Cefquinome Against Actinobacillus pleuropneumoniae.	Zhang L, Zhou Z, Gu X, Huang S, Shen X, Ding H.	Front Vet Sci	10.3389/fvets.2020.00448	2020
Phylogeny	Comparative Genome Sequence Analysis of Actinobacillus pleuropneumoniae Serovar 8 Isolates From Norway, Denmark, and the United Kingdom Indicates Distinct Phylogenetic Lineages and Differences in Distribution of Antimicrobial Resistance Genes.	Cohen LM, Bosse JT, Stegger M, Li Y, Langford PR, Kielland C, Klem TB, Gulliksen SM, Ranheim B, Grontvedt CA, Angen O.	Front Microbiol	10.3389/fmicb.2021.729637	2021
Enzymology	The influence of Actinobacillus pleuropneumoniae infection on tulathromycin pharmacokinetics and lung tissue disposition in pigs.	Gajda A, Bladek T, Jablonski A, Posyniak A.	J Vet Pharmacol Ther	10.1111/jvp.12259	2016
	Swine Gut Lactic Acid Bacteria and Their Exopolysaccharides Differentially Modulate Toll-like Receptor Signaling Depending on the Agave Fructans Used as a Carbon Source.	Sanhueza-Carrera EA, Fernandez-Lainez C, Castro-De la Mora C, Ortega-Alvarez D, Mendoza-Camacho C, Cortez-Sanchez JM, Perez-Guille B, de Vos P, Lopez-Velazquez G.	Animals (Basel)	10.3390/ani15071047	2025
	Evaluation of an electrostatic precipitator in mitigating the transmission of airborne viruses in experimentally infected pigs.	Wang L, Moran J, Yang M, Olson BA, Hogan CJ, Torremorell M.	Vet Res	10.1186/s13567-025-01503-1	2025
Metabolism	Characterization of surfactant alterations in pigs infected with Actinobacillus pleuropneumoniae.	Busley D, Ochs M, Hoeltig D, Ganter M, Acevedo C, Schmiedl A, Hennig-Pauka I.	Exp Lung Res	10.3109/01902148.2015.1123327	2016
Enzymology	Amoxicillin-current use in swine medicine.	Burch DGS, Sperling D.	J Vet Pharmacol Ther	10.1111/jvp.12482	2018
	Impact of maternally derived immunity on immune responses elicited by piglet early vaccination against the most common pathogens involved in porcine respiratory disease complex.	Martinez-Boixaderas N, Garza-Moreno L, Sibila M, Segales J.	Porcine Health Manag	10.1186/s40813-022-00252-3	2022
	Comparative Genomics of Actinobacillus pleuropneumoniae Serotype 8 Reveals the Importance of Prophages in the Genetic Variability of the Species.	Prado IGO, da Silva GC, Crispim JS, Vidigal PMP, Nascimento M, Santana MF, Bazzolli DMS.	Int J Genomics	10.1155/2020/9354204	2020
	In Vitro Glycosylation of the Membrane Protein gamma-Sarcoglycan in Nanodiscs.	Harris MS, Dolan RF, Bryce JR, Ewusi JG, Cook GA.	ACS Omega	10.1021/acsomega.3c06135	2023
	Observations on the associations between damaging and aggressive behaviors, related lesions, and their implications for the welfare of pigs in the grower-finisher period.	Markland L, Diaz JAC, Boyle LA, Pessoa J, van Staaveren N.	Front Vet Sci	10.3389/fvets.2025.1523663	2025
	Remotely Sensed Imagery for Early Detection of Respiratory Disease in Pigs: A Pilot Study.	Jorquera-Chavez M, Fuentes S, Dunshea FR, Warner RD, Poblete T, Morrison RS, Jongman EC.	Animals (Basel)	10.3390/ani10030451	2020
	The role of co-infections in M. hyopneumoniae outbreaks among heavy fattening pigs: a field study.	Tonni M, Formenti N, Boniotti MB, Guarneri F, Scali F, Romeo C, Pasquali P, Pieters M, Maes D, Alborali GL.	Vet Res	10.1186/s13567-022-01061-w	2022
Enzymology	Pharmacokinetics of tulathromycin in edible tissues of healthy and experimentally infected pigs with Actinobacillus pleuropneumoniae.	Bladek T, Posyniak A, Jablonski A, Gajda A.	Food Addit Contam Part A Chem Anal Control Expo Risk Assess	10.1080/19440049.2015.1078915	2015
Metabolism	Biochemical characterization of a novel beta-galactosidase from Paenibacillus barengoltzii suitable for lactose hydrolysis and galactooligosaccharides synthesis.	Liu Y, Chen Z, Jiang Z, Yan Q, Yang S.	Int J Biol Macromol	10.1016/j.ijbiomac.2017.06.073	2017
	Multiplex analysis of pro-inflammatory cytokines in serum of Actinobacillus pleuropneumoniae-infected pigs.	Wyns H, Croubels S, Vandekerckhove M, Demeyere K, De Backer P, Goddeeris BM, Meyer E.	Res Vet Sci	10.1016/j.rvsc.2015.07.006	2015
	The rapid detection of procalcitonin in septic serum using immunoaffinity MALDI chips.	Dvorak J, Novakova J, Kraftova L, Studentova V, Matejovic M, Radej J, Karvunidis T, Horak J, Kralovcova M, Hrabak J, Kalaninova Z, Volny M, Novak P, Pompach P.	Clin Proteomics	10.1186/s12014-023-09410-3	2023
	Cross-Correlation between Biosecurity Measures and the Detection of Viral and Bacterial Agents on German Farms with Respiratory Disease.	Stadler J, Lillie-Jaschniski K, Zwickl S, Zoels S, Theuns S, Ritzmann M, Vereecke N.	Transbound Emerg Dis	10.1155/2024/6205899	2024
Phylogeny	Development of a 3-transcript host expression assay to differentiate between viral and bacterial infections in pigs.	Hjertner B, Lutzelschwab C, Schieck E, Nzau B, Henson S, Sjolund M, Fossum C, Magnusson U.	PLoS One	10.1371/journal.pone.0256106	2021
	Resilience of swine nasal microbiota to influenza A virus challenge in a longitudinal study.	Hau SJ, Nielsen DW, Mou KT, Alt DP, Kellner S, Brockmeier SL.	Vet Res	10.1186/s13567-023-01167-9	2023
	Regulatory Mechanisms and Physiological Impacts of Quorum Sensing in Gram-Negative Bacteria.	Chu X, Yang Q.	Infect Drug Resist	10.2147/idr.s485388	2024
	Description of patterns of ear and tail lesions during the grower-finisher period in a commercial pig farm	van Staaveren N, Pessoa J, Boyle L, Calderon Diaz J.	Porcine Health Manag		2024
	Trimeric autotransporter adhesins contribute to Actinobacillus pleuropneumoniae pathogenicity in mice and regulate bacterial gene expression during interactions between bacteria and porcine primary alveolar macrophages.	Qin W, Wang L, Zhai R, Ma Q, Liu J, Bao C, Zhang H, Sun C, Feng X, Gu J, Du C, Han W, Langford PR, Lei L.	Antonie Van Leeuwenhoek	10.1007/s10482-015-0609-x	2016
	Study on the Effect of Phillyrin on Streptococcus suis In Vivo and In Vitro.	Yuan F, Zheng L, Wang M, Liu W, Li X, Gao T, Guo R, Liu Z, Yang K, Li C, Wu Q, Zhu J, Tian Y, Zhou D.	Biomolecules	10.3390/biom14121542	2024
	Lactoferrin Affects the Viability of Bacteria in a Biofilm and the Formation of a New Biofilm Cycle of Mannheimia haemolytica A2.	Ruiz-Mazon L, Ramirez-Rico G, de la Garza M.	Int J Mol Sci	10.3390/ijms25168718	2024
Enzymology	Transcriptional Response of Pectobacterium carotovorum to Cinnamaldehyde Treatment.	Jung J, Jo D, Kim SJ.	J Microbiol Biotechnol	10.4014/jmb.2311.11043	2024
	The CpxAR Two-Component System Contributes to Growth, Stress Resistance, and Virulence of Actinobacillus pleuropneumoniae by Upregulating wecA Transcription.	Yan K, Liu T, Duan B, Liu F, Cao M, Peng W, Dai Q, Chen H, Yuan F, Bei W.	Front Microbiol	10.3389/fmicb.2020.01026	2020
	Undocked Tails, Mycoplasma-like Lesions and Gastric Ulcers in Slaughtering Pigs: What Connection?	Scollo A, Abbas M, Contiero B, Gottardo F.	Animals (Basel)	10.3390/ani13020305	2023
	The role of veterinary drug use in driving antimicrobial resistance of Staphylococcus aureus isolates in smallholder swine farms in Central Vietnam.	Chao NV, Dung HT, Thanh Tam VT, Hang PT, Hien BT.	Open Vet J	10.5455/ovj.2025.v15.i2.34	2025
Pathogenicity	Survey of susceptibility to marbofloxacin in bacteria isolated from diseased pigs in Europe.	El Garch F, Kroemer S, Galland D, Morrissey I, Woehrle F.	Vet Rec	10.1136/vr.103954	2017
Genetics	Whole Genome Sequence Analysis of Pig Respiratory Bacterial Pathogens with Elevated Minimum Inhibitory Concentrations for Macrolides.	Dayao DA, Seddon JM, Gibson JS, Blackall PJ, Turni C.	Microb Drug Resist	10.1089/mdr.2015.0214	2016
Pathogenicity	Sub-inhibitory concentrations of penicillin G induce biofilm formation by field isolates of Actinobacillus pleuropneumoniae.	Hathroubi S, Fontaine-Gosselin SE, Tremblay YD, Labrie J, Jacques M.	Vet Microbiol	10.1016/j.vetmic.2015.06.011	2015
	Identification and Characterization of the Two Glycosyltransferases Required for the Polymerization of the HS:1 Serotype Capsular Polysaccharide of Campylobacter jejuni G1.	Bourland R, Narindoshvili T, Raushel FM.	Biochemistry	10.1021/acs.biochem.4c00803	2025
Pathogenicity	The antibacterial mechanism of berberine against Actinobacillus pleuropneumoniae.	Kang S, Li Z, Yin Z, Jia R, Song X, Li L, Chen Z, Peng L, Qu J, Hu Z, Lai X, Wang G, Liang X, He C, Yin L.	Nat Prod Res	10.1080/14786419.2014.1001388	2015
	Sero- and apx-typing of German Actinobacillus pleuropneumoniae field isolates from 2010 to 2019 reveals a predominance of serovar 2 with regular apx-profile.	Schuwerk L, Hoeltig D, Waldmann KH, Valentin-Weigand P, Rohde J.	Vet Res	10.1186/s13567-020-00890-x	2021
	A case of pericarditis caused by Mycoplasma hyorhinis in a weaned piglet.	Ustulin M, Rossi E, Vio D.	Porcine Health Manag	10.1186/s40813-021-00211-4	2021
	Economic losses associated with respiratory and helminth infections in domestic pigs in Lira district, Northern Uganda.	Oba P, Dione M, Mwiine FN, Wieland B, Erume J, Ouma E.	Front Vet Sci	10.3389/fvets.2023.1198461	2023
	Lesions and pathogens found in pigs that died during the nursery period in five Danish farms.	Barington K, Eriksen EO, Kudirkiene E, Pankoke K, Hartmann KT, Hansen MS, Jensen HE, Blirup-Plum SA, Jorgensen BM, Nielsen JP, Olsen JE, Goecke NB, Larsen LE, Pedersen KS.	Porcine Health Manag	10.1186/s40813-023-00319-9	2023
Pathogenicity	Development of Actinobacillus pleuropneumoniae ApxI, ApxII, and ApxIII-specific ELISA methods for evaluation of vaccine efficiency.	Jung M, Won H, Shin MK, Oh MW, Shim S, Yoon I, Yoo HS.	J Vet Sci	10.4142/jvs.2019.20.e2	2019
	Cronobacter sakazakii lysozyme inhibitor LprI mediated by HmsP and c-di-GMP is essential for biofilm formation and virulence.	Ji X, Fan D, Wang J, Zhang B, Hu Y, Lv H, Wu J, Sun Y, Liu J, Zhang Y, Wang S.	Appl Environ Microbiol	10.1128/aem.01564-24	2024
	Effectiveness of gilt acclimatization - improvement procedures in a farm with recurrent outbreaks of porcine epidemic diarrhea.	Suwan P, Boonsoongnern A, Phuttapatimok S, Sukmak M, Jirawattanapong P, Chumsing W, Boodde O, Woramahatthanon K, Woonwong Y.	Vet World	10.14202/vetworld.2023.1695-1701	2023
	Establishment and Application of a Quadruplex Real-Time Reverse-Transcription Polymerase Chain Reaction Assay for Differentiation of Porcine Reproductive and Respiratory Syndrome Virus, Porcine Circovirus Type 2, Porcine Circovirus Type 3, and Streptococcus suis.	Wang G, Zhu H, Zhan C, Chen P, Wu B, Peng Z, Qian P, Cheng G.	Microorganisms	10.3390/microorganisms12030427	2024
	Genomic Analysis of IgG Antibody Response to Common Pathogens in Commercial Sows in Health-Challenged Herds.	Sanglard LP, PigGen Canada, Mote BE, Willson P, Harding JCS, Plastow GS, Dekkers JCM, Serao NVL.	Front Genet	10.3389/fgene.2020.593804	2020
	Isolates, Antimicrobial Susceptibility Profiles and Multidrug Resistance of Bacteria Cultured from Pig Submissions in New Zealand.	Riley CB, Chidgey KL, Bridges JP, Gordon E, Lawrence KE.	Animals (Basel)	10.3390/ani10081427	2020
	Development of a triplex quantitative reverse transcription-polymerase chain reaction for the detection of porcine epidemic diarrhea virus, porcine transmissible gastroenteritis virus, and porcine rotavirus A.	Luo T, Li K, Li C, Xia C, Gao C.	Front Microbiol	10.3389/fmicb.2024.1390328	2024
	A cross-sectional survey on respiratory disease in a cohort of Irish pig farms.	Rodrigues da Costa M, Fitzgerald RM, Manzanilla EG, O'Shea H, Moriarty J, McElroy MC, Leonard FC.	Ir Vet J	10.1186/s13620-020-00176-w	2020
	Prevention of umbilical outpouchings and mortality in pigs: Meloxicam, tying, cutting, and chlorhexidine versus amoxicillin or no treatment? A clinical field trial.	Hansen ML, Larsen I, Jensen TB, Kristensen CS, Pedersen KS.	Porcine Health Manag	10.1186/s40813-024-00358-w	2024
Enzymology	Isolation of Actinobacillus pleuropneumoniae from layer hens showing clinical signs of infectious coryza.	Perez Marquez VM, Ochoa JL, Cruz CV, Alonso PS, Olmedo-Alvarez G, Vaca S, Abascal EN.	Avian Dis	10.1637/10798-021314-case.1	2014
	New Insights into Neutrophil Extracellular Trap (NETs) Formation from Porcine Neutrophils in Response to Bacterial Infections.	Bonilla MC, Quiros ON, Wendt M, Hennig-Pauka I, Morgelin M, von Kockritz-Blickwede M, de Buhr N.	Int J Mol Sci	10.3390/ijms23168953	2022
Metabolism	Flagellar expression in clinical isolates of non-typeable Haemophilus influenzae.	Carabarin-Lima A, Lozano-Zarain P, Castaneda-Lucio M, Martinez de la Pena CF, Martinez-Garcia J, Flores NL, Cruz EC, Gonzalez-Posos S, Rocha-Gracia RDC.	J Med Microbiol	10.1099/jmm.0.000471	2017
	Actinobacillus pleuropneumoniae encodes multiple phase-variable DNA methyltransferases that control distinct phasevarions.	Nahar N, Tram G, Jen FE, Phillips ZN, Weinert LA, Bosse JT, Jabbari JS, Gouil Q, Du MRM, Ritchie ME, Bowden R, Langford PR, Tucker AW, Jennings MP, Turni C, Blackall PJ, Atack JM.	Nucleic Acids Res	10.1093/nar/gkad091	2023
	[TLR-4 involvement in pyroptosis of mice with pulmonary inflammation infected by Actinobacillus pleuropneumoniae].	Hu P, Huang F, Niu J, Tang Z.	Wei Sheng Wu Xue Bao		2015
Genetics	Evaluation of Machine Learning Models for Predicting Antimicrobial Resistance of Actinobacillus pleuropneumoniae From Whole Genome Sequences.	Liu Z, Deng D, Lu H, Sun J, Lv L, Li S, Peng G, Ma X, Li J, Li Z, Rong T, Wang G.	Front Microbiol	10.3389/fmicb.2020.00048	2020
Metabolism	In silico analysis of putative drug and vaccine targets of the metabolic pathways of Actinobacillus pleuropneumoniae using a subtractive/comparative genomics approach.	Birhanu BT, Lee SJ, Park NH, Song JB, Park SC.	J Vet Sci	10.4142/jvs.2018.19.2.188	2018
	The kinetics of maternal and self-developed Streptococcus suis-specific antibodies.	Vreman S, Jansen R, Bastian M, Beckers P, van Riet M, Fijten H, Fledderus J, de Greeff A, Winkelman H, Stockhofe-Zurwieden N, Faba L, Wisselink HJ, Vrieling M.	Porcine Health Manag	10.1186/s40813-025-00422-z	2025
	Serine protease Rv2569c facilitates transmission of Mycobacterium tuberculosis via disrupting the epithelial barrier by cleaving E-cadherin.	Zang X, Zhang J, Jiang Y, Feng T, Cui Y, Wang H, Cui Z, Dang G, Liu S.	PLoS Pathog	10.1371/journal.ppat.1012214	2024
Pathogenicity	Efficacy of enteric-coated tilmicosin granules in pigs artificially infected with Actinobacillus pleuropneumoniae serotype 2.	Dong Z, Zhou XZ, Sun JC, Meng XB, Li HS, Cheng FS, Wei XJ, Li B, Wang WW, Zhang JY.	Vet Med Sci	10.1002/vms3.198	2020
	Sampling and Characterization of Bioaerosols in Poultry Houses.	Smith BL, King MD.	Microorganisms	10.3390/microorganisms11082068	2023
Pathogenicity	Variation in the Antimicrobial Susceptibility of Actinobacillus pleuropneumoniae Isolates in a Pig, Within a Batch of Pigs, and Among Batches of Pigs from One Farm.	Dayao DA, Dawson S, Kienzle MJ, Gibson JS, Blackall PJ, Turni C.	Microb Drug Resist	10.1089/mdr.2014.0265	2015
Metabolism	Identification of FtpA, a Dps-Like Protein Involved in Anti-Oxidative Stress and Virulence in Actinobacillus pleuropneumoniae.	Tang H, Zhang Q, Han W, Wang Z, Pang S, Zhu H, Tan K, Liu X, Langford PR, Huang Q, Zhou R, Li L.	J Bacteriol	10.1128/jb.00326-21	2022
Enzymology	Isolation and characterization of atypical Actinobacillus pleuropneumoniae serovar 15 lacking the apxIICA genes in Japan.	Teshima K, Hirano H, Ushiyama K, Shibuya K, Nagai S, Sasakawa C, To H.	J Vet Med Sci	10.1292/jvms.18-0421	2019
	Immunomodulatory effects of tulathromycin on apoptosis, efferocytosis, and proinflammatory leukotriene B4 production in leukocytes from Actinobacillus pleuropneumoniae-or zymosan-challenged pigs.	Duquette SC, Fischer CD, Williams AC, Sajedy S, Feener TD, Bhargava A, Reti KL, Muench GP, Morck DW, Allison J, Lucas MJ, Buret AG.	Am J Vet Res	10.2460/ajvr.76.6.507	2015
	The Prevalence of Pasteurella Multocida from Farm Pigs in Serbia	Radanovic O, Bozidar Savic, Branislav Kureljusic, Dobrila Jakic-Dimic, Jadranka Zutic.	Macedonian veterinary review.		2016
Metabolism	Isolation and molecular characterization of a urease-negative Actinobacillus pleuropneumoniae mutant.	Ito H, Takahashi S, Asai T, Tamura Y, Yamamoto K.	J Vet Diagn Invest	10.1177/1040638717742436	2018
	Galactose-1-phosphate uridyltransferase (GalT), an in vivo-induced antigen of Actinobacillus pleuropneumoniae serovar 5b strain L20, provided immunoprotection against serovar 1 strain MS71.	Zhang F, Zhao Q, Quan K, Zhu Z, Yang Y, Wen X, Chang YF, Huang X, Wu R, Wen Y, Yan Q, Huang Y, Ma X, Han X, Cao S.	PLoS One	10.1371/journal.pone.0198207	2018
	Antimicrobial use in lactating sows, piglets, nursery, and grower-finisher pigs on swine farms in Ontario, Canada during 2017 and 2018.	Bosman AL, Deckert AE, Carson CA, Poljak Z, Reid-Smith RJ, McEwen SA.	Porcine Health Manag	10.1186/s40813-022-00259-w	2022
	Nasal immunization with M cell-targeting ligand-conjugated ApxIIA toxin fragment induces protective immunity against Actinobacillus pleuropneumoniae infection in a murine model.	Park J, Seo KW, Kim SH, Lee HY, Kim B, Lim CW, Kim JH, Yoo HS, Jang YS.	Vet Microbiol	10.1016/j.vetmic.2015.03.005	2015
	Actinobacillus pleuropneumoniae two-component system QseB/QseC regulates the transcription of PilM, an important determinant of bacterial adherence and virulence.	Liu J, Hu L, Xu Z, Tan C, Yuan F, Fu S, Cheng H, Chen H, Bei W.	Vet Microbiol	10.1016/j.vetmic.2015.02.033	2015
	Identification, Biochemical Characterization, and In Vivo Detection of a Zn-Metalloprotease with Collagenase Activity from Mannheimia haemolytica A2.	Ramirez-Rico G, Martinez-Castillo M, Ruiz-Mazon L, Meneses-Romero EP, Palacios JAF, Diaz-Aparicio E, Abascal EN, de la Garza M.	Int J Mol Sci	10.3390/ijms25021289	2024
	Indirect contacts between Danish pig farms - what are the frequencies and risk-reducing measures, and how can they be used in simulation models?	Fertner M, Conrady B, Rogind AS, Nielsen EO, Boklund A.	Acta Vet Scand	10.1186/s13028-024-00789-z	2025
	The Role of Vulture (Accipitriformes) Cutaneous Microbiota in Infectious Disease Protection.	Lobello M, Bava R, Castagna F, Sotgiu FD, Berlinguer F, Tilocca B.	Microorganisms	10.3390/microorganisms13040898	2025
	Cronobacter sakazakii Pyridoxal Kinase PdxY Mediated by TreR and pESA3 Is Essential for Vitamin B₆ (PLP) Maintenance and Virulence.	Lu P, Dong X, Ji X.	Appl Environ Microbiol	10.1128/aem.00924-23	2023
Enzymology	Actinobacillus pleuropneumoniae seroprevalence in farmed wild boars in Finland.	Halli O, Ala-Kurikka E, Wallgren P, Heinonen M.	J Zoo Wildl Med	10.1638/2014-0046.1	2014
	Macrophages largely contribute to heterologous anti-Propionibacterium acnes antibody-mediated protection from Actinobacillus pleuropneumoniae infection in mice.	Ma Q, Sun C, Yang F, Wang L, Qin W, Xia X, Feng X, Du C, Gu J, Han W, Lei L.	Microbiol Immunol	10.1111/1348-0421.12240	2015
Enzymology	What Matters in Piglets' Exposure to Antibiotics Administered through Drinking Water?	Chassan M, Hemonic A, Concordet D.	Antibiotics (Basel)	10.3390/antibiotics10091067	2021
	The Adh adhesin domain is required for trimeric autotransporter Apa1-mediated Actinobacillus pleuropneumoniae adhesion, autoaggregation, biofilm formation and pathogenicity.	Wang L, Qin W, Yang S, Zhai R, Zhou L, Sun C, Pan F, Ji Q, Wang Y, Gu J, Feng X, Du C, Han W, Langford PR, Lei L.	Vet Microbiol	10.1016/j.vetmic.2015.02.026	2015
Pathogenicity	Breed- and Line-Dependent Severity of Inflammation and Necrosis Syndrome in AI Boars, and the Related Risk of Inflammation and Necrosis in Their Progeny.	Becker S, Kochendoerfer E, Kuehling J, Gerhards K, Lechner M, Zinner S, Lautner M, Reiner G.	Vet Sci	10.3390/vetsci12100967	2025
	Gut microbiota contributes to protection against porcine deltacoronavirus infection in piglets by modulating intestinal barrier and microbiome.	Zhang Y, Si L, Shu X, Qiu C, Wan X, Li H, Ma S, Jin X, Wei Z, Hu H.	Microbiome	10.1186/s40168-025-02092-z	2025
Enzymology	Micromethods for Isolation and Structural Characterization of Lipid A, and Polysaccharide Regions of Bacterial Lipopolysaccharides.	Novikov A, Breton A, Caroff M.	Methods Mol Biol	10.1007/978-1-4939-6958-6_16	2017
Metabolism	Basal-Level Effects of (p)ppGpp in the Absence of Branched-Chain Amino Acids in Actinobacillus pleuropneumoniae.	Li G, Zhao Q, Luan T, Hu Y, Zhang Y, Li T, Wang C, Xie F, Zhang W, Langford PR, Liu S.	J Bacteriol	10.1128/jb.00640-19	2020
	Nasal immunization with mannan-decorated mucoadhesive HPMCP microspheres containing ApxIIA toxin induces protective immunity against challenge infection with Actinobacillus pleuropneumoiae in mice.	Li HS, Shin MK, Singh B, Maharjan S, Park TE, Kang SK, Yoo HS, Hong ZS, Cho CS, Choi YJ.	J Control Release	10.1016/j.jconrel.2016.05.032	2016
Metabolism	Actinobacillus pleuropneumoniae exotoxin ApxI induces cell death via attenuation of FAK through LFA-1.	Li SC, Cheng YT, Wang CY, Wu JY, Chen ZW, Wang JP, Lin JH, Hsuan SL.	Sci Rep	10.1038/s41598-021-81290-9	2021
Metabolism	MALDI MSI Reveals the Spatial Distribution of Protein Markers in Tracheobronchial Lymph Nodes and Lung of Pigs after Respiratory Infection.	Do T, Guran R, Jarosova R, Ondrackova P, Sladek Z, Faldyna M, Adam V, Zitka O.	Molecules	10.3390/molecules25235723	2020
	Chlorantraniliprole Enhances Cellular Immunity in Larvae of Spodoptera frugiperda (Smith) (Lepidoptera: Noctuidae).	Liu Q, Deng X, Wang L, Xie W, Zhang H, Li Q, Yang Q, Jiang C.	Insects	10.3390/insects15080586	2024
	Baicalin and probenecid protect against Glaesserella parasuis challenge in a piglet model.	Fu S, Liu S, Li J, Dong Q, Fu Y, Luo R, Sun Y, Tian X, Liu W, Zong B, Ye C, Lu Q, Qiu Y, Guo L.	Vet Res	10.1186/s13567-024-01352-4	2024
	Exposure of extensively farmed wild boars (Sus scrofa scrofa) to selected pig pathogens in Greece.	Marinou KA, Papatsiros VG, Gkotsopoulos EK, Odatzoglou PK, Athanasiou LV.	Vet Q	10.1080/01652176.2015.1022666	2015
	Differential gene expression profiling of Actinobacillus pleuropneumoniae during induction of primary alveolar macrophage apoptosis in piglets.	Wang L, Qin W, Ruidong Z, Liu S, Zhang H, Sun C, Feng X, Gu J, Du C, Han W, Langford PR, Lei L.	Microb Pathog	10.1016/j.micpath.2014.11.017	2015
	Co-Occurrence of Severe Equine Asthma and Palatal Disorders in Privately Owned Pleasure Horses.	Kozlowska N, Wierzbicka M, Pawlinski B, Domino M.	Animals (Basel)	10.3390/ani13121962	2023
	Characterization and protective activity of monoclonal antibodies directed against Fe (3+) ABC transporter substrate-binding protein of Glaesserella parasuis.	Zhu K, Yu D, An J, Li Y.	Vet Res	10.1186/s13567-021-00967-1	2021
Enzymology	Simulation study of the mechanisms underlying outbreaks of clinical disease caused by Actinobacillus pleuropneumoniae in finishing pigs.	Klinkenberg D, Tobias TJ, Bouma A, van Leengoed LA, Stegeman JA.	Vet J	10.1016/j.tvjl.2014.06.015	2014
	iTRAQ-based quantitative proteomic analysis of peripheral blood serum in piglets infected with Actinobacillus pleuropneumoniae.	Zhu R, Bao C, Liu B, Xiao J, Sun C, Feng X, Langford PR, Li Y, Lei L.	AMB Express	10.1186/s13568-020-01057-9	2020
Pathogenicity	Pharmacokinetic/pharmacodynamic evaluation of marbofloxacin in the treatment of Haemophilus parasuis and Actinobacillus pleuropneumoniae infections in nursery and fattener pigs using Monte Carlo simulations.	Vilalta C, Giboin H, Schneider M, El Garch F, Fraile L.	J Vet Pharmacol Ther	10.1111/jvp.12134	2014
	A descriptor-free machine learning framework to improve antigen discovery for bacterial pathogens	Podda M, Savojardo C, Luigi Martelli P, Casadio R, Sirbu A, Priami C, Brozzi A.	PLoS One		2025
	Infection dynamics and acute phase response of an Actinobacillus pleuropneumoniae field isolate of moderate virulence in pigs.	Gomez-Laguna J, Islas A, Munoz D, Ruiz A, Villamil A, Carrasco L, Quezada M.	Vet Microbiol	10.1016/j.vetmic.2014.08.015	2014
	Investigation of the Catalytic Mechanism of a Soluble N-glycosyltransferase Allows Synthesis of N-glycans at Noncanonical Sequons.	Hao Z, Guo Q, Feng Y, Zhang Z, Li T, Tian Z, Zheng J, Da LT, Peng W.	JACS Au	10.1021/jacsau.3c00214	2023
Phylogeny	Evaluation of a multiplex PCR to identify and serotype Actinobacillus pleuropneumoniae serovars 1, 5, 7, 12 and 15.	Turni C, Singh R, Schembri MA, Blackall PJ.	Lett Appl Microbiol	10.1111/lam.12287	2014
	Causes of Sow Mortality and Risks to Post-Mortem Findings in a Brazilian Intensive Swine Production System.	Monteiro MS, Matias DN, Poor AP, Dutra MC, Moreno LZ, Parra BM, Silva APS, Matajira CEC, de Moura Gomes VT, Barbosa MRF, Sato MIZ, Moreno AM.	Animals (Basel)	10.3390/ani12141804	2022
	Oral immunization against porcine pleuropneumonia using the cubic phase of monoolein and purified toxins of Actinobacillus pleuropneumoniae.	Lopez-Bermudez J, Quintanar-Guerrero D, Lara Puente H, Tortora Perez J, Suarez Guemez F, Ciprian Carrasco A, Mendoza Elvira S.	Vaccine	10.1016/j.vaccine.2014.09.056	2014
Enzymology	Preparation, characterization and pharmacokinetics of doxycycline hydrochloride and florfenicol polyvinylpyrroliddone microparticle entrapped with hydroxypropyl-beta-cyclodextrin inclusion complexes suspension.	Li X, Xie S, Pan Y, Qu W, Tao Y, Chen D, Huang L, Liu Z, Wang Y, Yuan Z.	Colloids Surf B Biointerfaces	10.1016/j.colsurfb.2016.02.027	2016
	Actinobacillus pleuropneumoniae grows as aggregates in the lung of pigs: is it time to refine our in vitro biofilm assays?	Tremblay YDN, Labrie J, Chenier S, Jacques M.	Microb Biotechnol	10.1111/1751-7915.12432	2017
Proteome	A single LC-MS/MS validated method for tulathromycin quantification in plasma, seminal plasma, and urine to be applied in a pharmacokinetic study in bull.	Barbarossa A, Bardhi A, Gazzotti T, Mari G, Pagliuca G.	Drug Test Anal	10.1002/dta.3270	2022
Transcriptome	Exploring transcriptomic and genomic differences between susceptible and resistant fetal pigs to maternal PRRSV infection at late gestation.	Ko H, Pasternak JA, Stothard P, Li C, Plastow GS, Harding JCS.	Vet Res	10.1186/s13567-025-01621-w	2025
	Correlations between lung pneumonic lesions and serologic status for key respiratory pathogens in slaughtered pigs in northern Uganda.	Oba P, Dione MM, Wieland B, Mwiine FN, Erume J.	Porcine Health Manag	10.1186/s40813-021-00233-y	2021
	Pharmacokinetic/pharmacodynamic evaluation of gamithromycin against rabbit pasteurellosis.	Wei XY, Zhang J, Zhang Y, Fu WZ, Zhong LG, Pan YD, Sun J, Liao XP, Liu YH, Zhou YF.	BMC Vet Res	10.1186/s12917-024-03988-y	2024
Enzymology	Development of two real-time polymerase chain reaction assays to detect Actinobacillus pleuropneumoniae serovars 1-9-11 and serovar 2.	Marois-Crehan C, Lacouture S, Jacques M, Fittipaldi N, Kobisch M, Gottschalk M.	J Vet Diagn Invest	10.1177/1040638713519090	2014
Metabolism	Acute and subacute response of iron, zinc, copper and selenium in pigs experimentally infected with Actinobacillus pleuropneumoniae.	Humann-Ziehank E, Menzel A, Roehrig P, Schwert B, Ganter M, Hennig-Pauka I.	Metallomics	10.1039/c4mt00148f	2014
	The Role of Pathology in the Diagnosis of Swine Respiratory Disease.	Sarli G, D'Annunzio G, Gobbo F, Benazzi C, Ostanello F.	Vet Sci	10.3390/vetsci8110256	2021
	Deletion of the znuA virulence factor attenuates Actinobacillus pleuropneumoniae and confers protection against homologous or heterologous strain challenge.	Yuan F, Liao Y, You W, Liu Z, Tan Y, Zheng C, BinWang, Zhou D, Tian Y, Bei W.	Vet Microbiol	10.1016/j.vetmic.2014.10.016	2014
	Streptococcus suis infection on European farms is associated with an altered tonsil microbiome and resistome.	Fredriksen S, Neila-Ibanez C, Hennig-Pauka I, Guan X, Dunkelberger J, de Oliveira IF, Ferrando ML, Correa-Fiz F, Aragon V, Boekhorst J, van Baarlen P, Wells JM.	Microb Genom	10.1099/mgen.0.001334	2024
Phylogeny	Comparative sequence analysis of the capsular polysaccharide loci of Actinobacillus pleuropneumoniae serovars 1-18, and development of two multiplex PCRs for comprehensive capsule typing.	Bosse JT, Li Y, Fernandez Crespo R, Lacouture S, Gottschalk M, Sarkozi R, Fodor L, Casas Amoribieta M, Angen O, Nedbalcova K, Holden MTG, Maskell DJ, Tucker AW, Wren BW, Rycroft AN, Langford PR, BRaDP1T consortium.	Vet Microbiol	10.1016/j.vetmic.2018.05.011	2018
Metabolism	Changes in gene expression of Actinobacillus pleuropneumoniae in response to anaerobic stress reveal induction of central metabolism and biofilm formation.	Li L, Zhu J, Yang K, Xu Z, Liu Z, Zhou R.	J Microbiol	10.1007/s12275-014-3456-y	2014
	Feasibility of Near-Infrared Spectroscopy in the Classification of Pig Lung Lesions.	Varra MO, Conter M, Recchia M, Alborali GL, Maisano AM, Ghidini S, Zanardi E.	Vet Sci	10.3390/vetsci11040181	2024
	Effect of bovine apo-lactoferrin on the growth and virulence of Actinobacillus pleuropneumoniae.	Luna-Castro S, Aguilar-Romero F, Samaniego-Barron L, Godinez-Vargas D, de la Garza M.	Biometals	10.1007/s10534-014-9752-5	2014
	Transmission of Actinobacillus pleuropneumoniae among weaned piglets on endemically infected farms.	Tobias TJ, Bouma A, van den Broek J, van Nes A, Daemen AJ, Wagenaar JA, Stegeman JA, Klinkenberg D.	Prev Vet Med	10.1016/j.prevetmed.2014.07.017	2014
	Efficacy of vaccination against Actinobacillus pleuropneumoniae in two Belgian farrow-to-finish pig herds with a history of chronic pleurisy.	Del Pozo Sacristan R, Michiels A, Martens M, Haesebrouck F, Maes D.	Vet Rec	10.1136/vr.101961	2014
Enzymology	Swine Influenza Virus and Association with the Porcine Respiratory Disease Complex in Pig Farms in Southern Brazil.	Schmidt C, Cibulski SP, Andrade CP, Teixeira TF, Varela AP, Scheffer CM, Franco AC, de Almeida LL, Roehe PM.	Zoonoses Public Health	10.1111/zph.12223	2016
	Galleria mellonella is an effective model to study Actinobacillus pleuropneumoniae infection.	Pereira MF, Rossi CC, Vieira de Queiroz M, Martins GF, Isaac C, Bosse JT, Li Y, Wren BW, Terra VS, Cuccui J, Langford PR, Bazzolli DMS.	Microbiology (Reading)	10.1099/mic.0.083923-0	2015
	Optimization of immune strategy for a construct of Salmonella-delivered ApxIA, ApxIIA, ApxIIIA and OmpA antigens of Actinobacillus pleuropneumoniae for prevention of porcine pleuropneumonia using a murine model.	Hur J, Lee JH.	Vet Res Commun	10.1007/s11259-013-9586-6	2014
Enzymology	A cohort study on Actinobacillus pleuropneumoniae colonisation in suckling piglets.	Tobias TJ, Klinkenberg D, Bouma A, van den Broek J, Daemen AJ, Wagenaar JA, Stegeman JA.	Prev Vet Med	10.1016/j.prevetmed.2014.02.008	2014
Metabolism	Sequence and structural diversity of transferrin receptors in Gram-negative porcine pathogens.	Curran DM, Adamiak PJ, Fegan JE, Qian C, Yu RH, Schryvers AB.	Vaccine	10.1016/j.vaccine.2015.07.097	2015
Enzymology	Microdialysis Determination of Cefquinome Pharmacokinetics in Murine Thigh From Healthy, Neutropenic, and Actinobacillus pleuropneumoniae-Infected Mice.	Zhang L, Yao L, Kang Z, Huang Z, Gu X, Shen X, Ding H.	Front Pharmacol	10.3389/fphar.2019.00249	2019
	Construction of an Escherichia coli chassis for efficient biosynthesis of human-like N-linked glycoproteins.	Bao Z, Gao Y, Song Y, Ding N, Li W, Wu Q, Zhang X, Zheng Y, Li J, Hu X.	Front Bioeng Biotechnol	10.3389/fbioe.2024.1370685	2024
	PAPreC: A Pipeline for Antigenicity Prediction Comparison Methods across Bacteria.	Martins YC, Cerqueira E Costa MO, Palumbo MC, F Do Porto D, Custodio FL, Trevizani R, Nicolas MF.	ACS Omega	10.1021/acsomega.4c07147	2025
	Scoring pleurisy in slaughtered pigs using convolutional neural networks.	Trachtman AR, Bergamini L, Palazzi A, Porrello A, Capobianco Dondona A, Del Negro E, Paolini A, Vignola G, Calderara S, Marruchella G.	Vet Res	10.1186/s13567-020-00775-z	2020
	Identification of QTL affecting resistance/susceptibility to acute Actinobacillus pleuropneumoniae infection in swine.	Reiner G, Bertsch N, Hoeltig D, Selke M, Willems H, Gerlach GF, Tuemmler B, Probst I, Herwig R, Drungowski M, Waldmann KH.	Mamm Genome	10.1007/s00335-013-9497-4	2014
Pathogenicity	Mutant prevention and minimum inhibitory concentration drug values for enrofloxacin, ceftiofur, florfenicol, tilmicosin and tulathromycin tested against swine pathogens Actinobacillus pleuropneumoniae, Pasteurella multocida and Streptococcus suis.	Blondeau JM, Fitch SD.	PLoS One	10.1371/journal.pone.0210154	2019
	Successful Treatment of Bullous Pemphigoid Lesions by Berberine Stamp Therapy: A Case Report and Literature Review.	Cheng L, Wang Y, Lu H, Guo W, Yan G, Zhu J, Guo D, Li F.	Front Med (Lausanne)	10.3389/fmed.2022.938761	2022
	Use of Subtherapeutic Tylvalosin Against Mycoplasma hyopneumoniae: Implications For Respiratory Microbiome Dysbiosis and Swine Lung Health.	Toledo LT, Polveiro RC, Diamantino CA, Simao GMR, Pereira CER, Costa EF, Moreira MAS, Marks FS.	Transbound Emerg Dis	10.1155/tbed/8903237	2025
	A descriptive study of acute outbreaks of respiratory disease in Norwegian fattening pig herds.	Cohen LM, Grontvedt CA, Klem TB, Gulliksen SM, Ranheim B, Nielsen JP, Valheim M, Kielland C.	Acta Vet Scand	10.1186/s13028-020-00529-z	2020
	Florfenicol sustained-release granules: an in vitro-in vivo correlation study in pigs.	Yang WC, Liu ZY, Zhang YX, Yu Y, Shen Y, Xu Y, Huang XH.	BMC Vet Res	10.1186/s12917-023-03631-2	2023
	Identification of a Novel Linear B-Cell Epitope of HbpA Protein from Glaesserella parasuis Using Monoclonal Antibody.	Liu G, Wang K, Yang Z, Tang X, Chang YF, Dai K, Tang X, Hu B, Zhang Y, Cao S, Huang X, Yan Q, Wu R, Zhao Q, Du S, Wen X, Wen Y.	Int J Mol Sci	10.3390/ijms24108638	2023
Metabolism	Channel formation by RTX-toxins of pathogenic bacteria: Basis of their biological activity.	Benz R.	Biochim Biophys Acta	10.1016/j.bbamem.2015.10.025	2016
	Computational Network Inference for Bacterial Interactomics.	James K, Munoz-Munoz J.	mSystems	10.1128/msystems.01456-21	2022
	MicroRNA-127 promotes anti-microbial ability in porcine alveolar macrophages via S1PR3/TLR signaling pathway.	Zhou H, Qian Y, Liu J.	J Vet Sci	10.4142/jvs.22110	2023
	Factors associated with herd-level PRRSV infection and age-time to seroconversion in farrow-to-finish herds.	Fablet C, Marois-Crehan C, Grasland B, Simon G, Rose N.	Vet Microbiol	10.1016/j.vetmic.2016.06.006	2016
Pathogenicity	Deletion of two-component system QseBC weakened virulence of Glaesserella parasuis in a murine acute infection model and adhesion to host cells.	Yan X, Dai K, Gu C, Yu Z, He M, Xiao W, Zhao M, He L.	PeerJ	10.7717/peerj.13648	2022
Metabolism	Exploring a combined Escherichia coli-based glycosylation and in vitro transglycosylation approach for expression of glycosylated interferon alpha.	Prabhu SK, Yang Q, Tong X, Wang LX.	Bioorg Med Chem	10.1016/j.bmc.2021.116037	2021
	Swine influenza A virus infection sets the local immunological landscape in subsequent infection with porcine reproductive and respiratory syndrome virus.	Grevelinger J, Bourry O, Schmidt S, Meurens F, Deblanc C, Hervet C, Perrin A, Gorin S, Le Dimna M, Queguiner S, Larcher T, Renson P, Paboeuf F, Gerner W, Bertho N, Simon G.	Vet Res	10.1186/s13567-025-01536-6	2025
	Characterisation of antimicrobial usage in Danish pigs in 2020.	Moura P, Sandberg M, Hog BB, Niza-Ribeiro J, Nielsen EO, Alban L.	Front Vet Sci	10.3389/fvets.2023.1155811	2023
	The intrinsic macrolide resistome of Escherichia coli.	Ma Y, Pirolo M, Jana B, Mebus VH, Guardabassi L.	Antimicrob Agents Chemother	10.1128/aac.00452-24	2024
	Epidemiology Tools to Evaluate the Control of Proliferative Enteropathy in Commercial Pig Herds.	Collins A, Collins C.	Animals (Basel)	10.3390/ani14091357	2024
Enzymology	Beyond anaerobic respiration-new physiological roles for DmsABC and other S-/N-oxide reductases in Escherichia coli.	Zhong Q, Nasreen M, Yang R, Struwe M, Kobe B, Kappler U.	J Bacteriol	10.1128/jb.00463-24	2025
	Review on the methodology to assess respiratory tract lesions in pigs and their production impact.	Maes D, Sibila M, Pieters M, Haesebrouck F, Segales J, de Oliveira LG.	Vet Res	10.1186/s13567-023-01136-2	2023
	Cross-sectional study of seropositivity, lung lesions and associated risk factors of the main pathogens of Porcine Respiratory Diseases Complex (PRDC) in Goiás, Brazil.	Galdeano JVB, Baraldi TG, Ferraz MES, de Souza Almeida HM, Mechler-Dreibi ML, Costa WMT, Montassier HJ, Mathias LA, de Oliveira LG.	Porcine Health Manag	10.1186/s40813-019-0130-0	2019
	Identification of proteins of Propionibacterium acnes for use as vaccine candidates to prevent infection by the pig pathogen Actinobacillus pleuropneumoniae.	Li L, Sun C, Yang F, Yang S, Feng X, Gu J, Han W, Langford PR, Lei L.	Vaccine	10.1016/j.vaccine.2013.08.054	2013
	p518, a small floR plasmid from a South American isolate of Actinobacillus pleuropneumoniae.	da Silva GC, Rossi CC, Santana MF, Langford PR, Bosse JT, Bazzolli DMS.	Vet Microbiol	10.1016/j.vetmic.2017.04.019	2017
Phylogeny	The blood pressure lowering effect of beetroot juice is impaired in periodontitis and recovered after periodontal treatment.	Sanchez-Orozco NY, Rosier BT, Ruiz-Gutierrez A, Marquez-Sandoval F, Artacho A, Carrera-Quintanar L, Mira A.	NPJ Biofilms Microbiomes	10.1038/s41522-024-00622-5	2025
Pathogenicity	Comparative activities of selected fluoroquinolones against dynamic populations of Actinobacillus pleuropneumoniae in an in vitro model of time-kill continuous culture experiment.	Damte D, Lee SJ, Yohannes SB, Hossain MA, Suh JW, Park SC.	Int J Antimicrob Agents	10.1016/j.ijantimicag.2013.08.011	2013
	Evaluation of the efficacy of the antimicrobial peptide HJH-3 in chickens infected with Salmonella Pullorum.	Xu Y, Wang Q, Dong M, Song H, Hang B, Sun Y, Zhang H, Hu J.	Front Microbiol	10.3389/fmicb.2023.1102789	2023
	Molecular Characterization and Phylogenetic Analysis of Outer membrane protein P2 (OmpP2) of Glaesserella (Haemophilus) parasuis Isolates in Central State of Peninsular Malaysia.	Lee CY, Ong HX, Tan CY, Low SE, Phang LY, Lai J, Ooi PT, Fong MWC.	Pathogens	10.3390/pathogens12020308	2023
	PPIA, HPRT1, and YWHAZ are suitable reference genes for quantitative polymerase chain reaction assay of the hypothalamic-pituitary-gonadal axis in sows.	Kim HD, Jo CH, Choe YH, Lee HJ, Jang M, Bae SG, Yun SH, Lee SL, Rho GJ, Kim SJ, Lee WJ.	Anim Biosci	10.5713/ab.22.0083	2022
	Main Causes of Death in Piglets from Different Brazilian Nursery Farms Based on Clinical, Microbiological, and Pathological Aspects.	Menegatt JCO, Perosa FF, Gris AH, Piva MM, Serena GC, Bordignon DL, Reck C, Menin A, Watanabe TTN, Driemeier D.	Animals (Basel)	10.3390/ani13243819	2023
Enzymology	Alterations and correlations of the gut microbiome, metabolism and immunity in patients with primary biliary cirrhosis.	Lv LX, Fang DQ, Shi D, Chen DY, Yan R, Zhu YX, Chen YF, Shao L, Guo FF, Wu WR, Li A, Shi HY, Jiang XW, Jiang HY, Xiao YH, Zheng SS, Li LJ.	Environ Microbiol	10.1111/1462-2920.13401	2016
	A polyvalent virosomal influenza vaccine induces broad cellular and humoral immunity in pigs.	Haach V, Bastos APA, Gava D, da Fonseca FN, Mores MAZ, Coldebella A, Franco AC, Schaefer R.	Virol J	10.1186/s12985-023-02153-5	2023
	Purchasing policy, quarantine and acclimation practices of breeding gilts in Belgian pig farms.	Bernaerdt E, Dewulf J, Verhulst R, Bonckaert C, Maes D.	Porcine Health Manag	10.1186/s40813-021-00205-2	2021
Pathogenicity	Subclinical Ovine Gammaherpesvirus 2-Related Infections in Free-Ranging Wild Boars (Sus scrofa) from Southern Brazil.	Headley SA, Fritzen JTT, Silva FHP, Minarelli SLM, Biondo LM, Kmetiuk LB, Biondo AW, Alfieri AA.	Pathogens	10.3390/pathogens13060515	2024
	Pharmacokinetic and Pharmacodynamic integration of tilmicosin against Mycoplasma gallisepticum in the target infection site in chickens.	Zhang N, Zhou M, Yan X, Liu J, Yuan S, Yang H, Ding H, Zhang D, Bai Y.	Front Vet Sci	10.3389/fvets.2022.952599	2022
Pathogenicity	Screening of Actinobacillus pleuropneumoniae LuxS inhibitors.	Li L, Sun L, Song Y, Wu X, Zhou X, Liu Z, Zhou R.	Curr Microbiol	10.1007/s00284-013-0403-9	2013
	The effect of norepinephrine on ovarian dysfunction by mediating ferroptosis in mice model.	Hong H, Xiao C, Weng L, Wang Q, Lai D.	Acta Biochim Biophys Sin (Shanghai)	10.3724/abbs.2024187	2024
	Emergence of a floR-carrying plasmid in extended spectrum beta-lactamase (ESBL) producing Pasteurella aerogenes, isolated from an avian species in China.	Yuan D, Wang M, Jia R, Chen S, Liu M, Zhao X, Yang Q, Wu Y, Zhang S, Huang J, Ou X, Mao S, Gao Q, Sun D, Tian B, Zhu D, Cheng A.	Poult Sci	10.1016/j.psj.2022.102207	2022
Phylogeny	Analysis of ORF5 sequences of Porcine Reproductive and Respiratory Syndrome virus (PRRSV) circulating within swine farms in Costa Rica.	Guzman M, Melendez R, Jimenez C, Piche M, Jimenez E, Leon B, Cordero JM, Ramirez-Carvajal L, Uribe A, Van Nes A, Stegeman A, Romero JJ.	BMC Vet Res	10.1186/s12917-021-02925-7	2021
Pathogenicity	Interleukin-6 dynamics as a basis for an early-warning monitor for sepsis and inflammation in individual pigs.	Tambuyzer T, De Waele T, Chiers K, Berckmans D, Goddeeris BM, Aerts JM.	Res Vet Sci	10.1016/j.rvsc.2014.03.014	2014
Enzymology	Glucose release kinetics of different feed ingredients and their impact on short-term growth of pigs by influencing carbon-nitrogen supply synchronization.	Huang M, Xue L, Wu Y, Sun Q, Xu Y, Li J, Yu X, Cao Y, Huang J, Zhang Z, Zhao J, Han D, Li D, Wang J.	J Anim Sci Biotechnol	10.1186/s40104-025-01198-6	2025
	Evidence of Illegitimate Recombination Between Two Pasteurellaceae Plasmids Resulting in a Novel Multi-Resistance Replicon, pM3362MDR, in Actinobacillus pleuropneumoniae.	Li Y, da Silva GC, Li Y, Rossi CC, Fernandez Crespo R, Williamson SM, Langford PR, Bazzolli DMS, Bosse JT.	Front Microbiol	10.3389/fmicb.2018.02489	2018
	Advancing PEDV Vaccination: Comparison between Inactivated and Flagellin N-Terminus-Adjuvanted Subunit Vaccines.	Murtaza A, Hoa NT, Dieu-Huong D, Afzal H, Tariq MH, Cheng LT, Chung YC.	Vaccines (Basel)	10.3390/vaccines12020139	2024
	Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins.	Lepesheva A, Osickova A, Holubova J, Jurnecka D, Knoblochova S, Espinosa-Vinals C, Bumba L, Skopova K, Fiser R, Osicka R, Sebo P, Masin J.	Sci Rep	10.1038/s41598-021-99112-3	2021
Enzymology	An enzyme-based protocol for cell-free synthesis of nature-identical capsular oligosaccharides from Actinobacillus pleuropneumoniae serotype 1.	Budde I, Litschko C, Fuhring JI, Gerardy-Schahn R, Schubert M, Fiebig T.	J Biol Chem	10.1074/jbc.ra120.012961	2020
	Draft Genome Sequences of Six Actinobacillus pleuropneumoniae Serotype 8 Brazilian Clinical Isolates: Insight into New Applications.	Pereira MF, Rossi CC, de Carvalho FM, de Almeida LG, Souza RC, de Vasconcelos AT, Bazzolli DM.	Genome Announc	10.1128/genomea.01585-14	2015
	Pigs Overexpressing Porcine beta-Defensin 2 Display Increased Resilience to Glaesserella parasuis Infection.	Huang J, Yang X, Wang A, Huang C, Tang H, Zhang Q, Fang Q, Yu Z, Liu X, Huang Q, Zhou R, Li L.	Antibiotics (Basel)	10.3390/antibiotics9120903	2020
Pathogenicity	Enhanced antibacterial effect of antibiotics in combination with silver nanoparticles against animal pathogens.	Smekalova M, Aragon V, Panacek A, Prucek R, Zboril R, Kvitek L.	Vet J	10.1016/j.tvjl.2015.10.032	2016
Proteome	Chicken Juice Enhances C. jejuni NCTC 11168 Biofilm Formation with Distinct Morphological Features and Altered Protein Expression	Sung K, Park M, Chon J, Kweon O, Paredes A, Khan S.	Foods		2024
Phylogeny	Integrative and conjugative elements of Pasteurella multocida: Prevalence and signatures in population evolution.	He J, Yang Z, Wang M, Jia R, Chen S, Liu M, Zhao X, Yang Q, Wu Y, Zhang S, Huang J, Ou X, Sun D, Tian B, He Y, Wu Z, Cheng A, Zhu D.	Virulence	10.1080/21505594.2024.2359467	2024
Pathogenicity	Monitoring of antimicrobial susceptibility of respiratory tract pathogens isolated from diseased cattle and pigs across Europe, 2009-2012: VetPath results.	El Garch F, de Jong A, Simjee S, Moyaert H, Klein U, Ludwig C, Marion H, Haag-Diergarten S, Richard-Mazet A, Thomas V, Siegwart E.	Vet Microbiol	10.1016/j.vetmic.2016.04.009	2016
	Screening for atypical porcine pestivirus in Swedish boar semen used for artificial insemination and a characterisation of the seminal RNA microbiome including the virome.	Stenberg H, Malmberg M, Hayer J.	BMC Vet Res	10.1186/s12917-023-03762-6	2023
	Pathogen presence in feral pigs and their movement around two commercial piggeries in Queensland, Australia.	Pearson HE, Toribio JA, Hernandez-Jover M, Marshall D, Lapidge SJ.	Vet Rec	10.1136/vr.102019	2014
	Pig Lung Immune Cytokine Response to the Swine Influenza Virus and the Actinobacillus Pleuropneumoniae Infection.	Czyzewska-Dors E, Dors A, Kwit K, Stasiak E, Pomorska-Mol M.	J Vet Res	10.1515/jvetres-2017-0036	2017
	Outer Membrane Lipoprotein Lip40 Modulates Adherence, Colonization, and Virulence of Actinobacillus pleuropneumoniae.	Liu J, Cao Y, Gao L, Zhang L, Gong S, Yang J, Zhao H, Yang D, Zhao J, Meng J, Gao Q, Qi C.	Front Microbiol	10.3389/fmicb.2018.01472	2018
Transcriptome	Transcriptome Analysis of miRNA and mRNA in Porcine Skeletal Muscle following Glaesserella parasuis Challenge.	Zhou H, Chen X, Deng X, Zhang X, Zeng X, Xu K, Chen H.	Genes (Basel)	10.3390/genes15030359	2024
	Pattern of Antibiotic Consumption in Two Italian Production Chains Differing by the Endemic Status for Porcine Reproductive and Respiratory Syndrome.	Trevisi P, Amatucci L, Ruggeri R, Romanelli C, Sandri G, Luise D, Canali M, Bosi P.	Front Vet Sci	10.3389/fvets.2022.840716	2022
	On-demand biomanufacturing through synthetic biology approach.	Tang C, Wang L, Zang L, Wang Q, Qi D, Dai Z.	Mater Today Bio	10.1016/j.mtbio.2022.100518	2023
	Complete Genome Sequence of MIDG2331, a Genetically Tractable Serovar 8 Clinical Isolate of Actinobacillus pleuropneumoniae.	Bosse JT, Chaudhuri RR, Li Y, Leanse LG, Fernandez Crespo R, Coupland P, Holden MT, Bazzolli DM, Maskell DJ, Tucker AW, Wren BW, Rycroft AN, Langford PR.	Genome Announc	10.1128/genomea.01667-15	2016
	Development of a highly sensitive point-of-care test for African swine fever that combines EZ-Fast DNA extraction with LAMP detection: Evaluation using naturally infected swine whole blood samples from Vietnam.	Ngan MT, Thi My Le H, Xuan Dang V, Thi Bich Ngoc T, Phan LV, Thi Hoa N, Quang Lam T, Thi Lan N, Notsu K, Sekiguchi S, Yamazaki Y, Yamazaki W.	Vet Med Sci	10.1002/vms3.1124	2023
	Porcine respiratory disease complex: Dynamics of polymicrobial infections and management strategies after the introduction of the African swine fever.	Assavacheep P, Thanawongnuwech R.	Front Vet Sci	10.3389/fvets.2022.1048861	2022
Phylogeny	Canada: Distribution of Streptococcus suis (from 2012 to 2014) and Actinobacillus pleuropneumoniae (from 2011 to 2014) serotypes isolated from diseased pigs.	Gottschalk M, Lacouture S.	Can Vet J		2015
	Identification of conserved surface proteins as novel antigenic vaccine candidates of Actinobacillus pleuropneumoniae.	Chen X, Xu Z, Li L, Chen H, Zhou R.	J Microbiol	10.1007/s12275-012-2214-2	2012
	Disease diagnostic coding to facilitate evidence-based medicine: current and future perspectives.	Derscheid RJ, Rahe MC, Burrough ER, Schwartz KJ, Arruda B.	J Vet Diagn Invest	10.1177/1040638721999373	2021
Pathogenicity	Bioinformatic discovery of type 11 secretion system (T11SS) cargo across the Proteobacteria.	Grossman AS, Mucci NC, Kauffman SJ, Rafi J, Goodrich-Blair H.	Microb Genom	10.1099/mgen.0.001406	2025
	Survival of Actinobacillus pleuropneumoniae outside the pig.	Assavacheep P, Rycroft AN.	Res Vet Sci	10.1016/j.rvsc.2012.07.024	2013
	Postweaning mortality in commercial swine production II: review of infectious contributing factors.	Gebhardt JT, Tokach MD, Dritz SS, DeRouchey JM, Woodworth JC, Goodband RD, Henry SC.	Transl Anim Sci	10.1093/tas/txaa052	2020
Phylogeny	Genomic insight into the diversity of Glaesserella parasuis isolates from 19 countries.	Gong X, Cui Q, Zhang W, Shi Y, Zhang P, Zhang C, Hu G, Sahin O, Wang L, Shen Z, Fu M.	mSphere	10.1128/msphere.00231-24	2024
Pathogenicity	Acquisition, co-option, and duplication of the rtx toxin system and the emergence of virulence in Kingella.	Morreale DP, Porsch EA, Kern BK, St Geme JW, Planet PJ.	Nat Commun	10.1038/s41467-023-39939-8	2023
	Serotyping and Antimicrobial Susceptibility Profiling of Glaesserella parasuis Isolated from Diseased Swine in Brazil.	Silva GFR, Moreno LZ, Matajira CEC, Silva APS, Araujo KM, Gomes VTM, Barbosa MRF, Sato MIZ, Moreno AM.	Pathogens	10.3390/pathogens11121443	2022
	Tildipirosin: An effective antibiotic against Glaesserella parasuis from an in vitro analysis.	Peres PR, Prigol SR, Martin CBG, Feronatod C, Surinach MC, Kreutz LC, Frandoloso R.	Vet Anim Sci	10.1016/j.vas.2020.100136	2020
	Erythema Multiforme Associated with Respiratory Disease in a Commercial Breeding Pig Herd.	Papatsiros VG, Athanasiou LV, Psalla D, Petridou E, Maragkakis GG, Papatsas I, Arsenakis I, Maes D.	Viral Immunol	10.1089/vim.2015.0063	2015
Pathogenicity	Membrane Interaction Characteristics of the RTX Toxins and the Cholesterol-Dependence of Their Cytolytic/Cytotoxic Activity.	Ostolaza H, Amuategi J.	Int J Mol Sci	10.3390/ijms25063131	2024
	Shifts in the swine nasal microbiota following Bordetella bronchiseptica challenge in a longitudinal study.	Nielsen DW, Hau SJ, Mou KT, Alt DP, Brockmeier SL.	Front Microbiol	10.3389/fmicb.2023.1260465	2023
	Structural insights into mechanism and specificity of the plant protein O-fucosyltransferase SPINDLY.	Zhu L, Wei X, Cong J, Zou J, Wan L, Xu S.	Nat Commun	10.1038/s41467-022-35234-0	2022
Enzymology	Detection of Actinobacillus pleuropneumoniae in drinking water from pig farms.	Loera-Muro VM, Jacques M, Tremblay YDN, Avelar-Gonzalez FJ, Loera Muro A, Ramirez-Lopez EM, Medina-Figueroa A, Gonzalez-Reynaga HM, Guerrero-Barrera AL.	Microbiology (Reading)	10.1099/mic.0.057992-0	2013
	Efficacy of Two Commercial Ready-To-Use PCV2 and Mycoplasma hyopneumoniae Vaccines under Field Conditions.	Lopez-Lorenzo G, Prieto A, Lopez-Novo C, Diaz P, Lopez CM, Morrondo P, Fernandez G, Diaz-Cao JM.	Animals (Basel)	10.3390/ani11061553	2021
	Differential Gene Expression in Porcine Lung Compartments after Experimental Infection with Mycoplasma hyopneumoniae.	Rosales RS, Risco D, Garcia-Nicolas O, Pallares FJ, Ramirez AS, Poveda JB, Nicholas RAJ, Salguero FJ.	Animals (Basel)	10.3390/ani14091290	2024
Metabolism	Resistance to selected beta-lactam antibiotics.	Nedbalcova K, Nechvatalova K, Pokludova L, Bures J, Kucerova Z, Koutecka L, Hera A.	Vet Microbiol	10.1016/j.vetmic.2014.02.004	2014
	Oral immunization of mice with Saccharomyces cerevisiae expressing a neutralizing epitope of ApxIIA exotoxin from Actinobacillus pleuropneumoniae induces systemic and mucosal immune responses.	Shin MK, Lee WJ, Jung MH, Cha SB, Shin SW, Yoo A, Kim DH, Yoo HS.	Microbiol Immunol	10.1111/1348-0421.12053	2013
	Genome-wide screening of lipoproteins in Actinobacillus pleuropneumoniae identifies three antigens that confer protection against virulent challenge.	Cao Y, Gao L, Zhang L, Zhou L, Yang J, Deng L, Zhao J, Qi C, Liu J.	Sci Rep	10.1038/s41598-020-58968-7	2020
	Analysis of Transfer of Tiamulin to Animal Tissue after Oral Administration: An Important Factor for Ensuring Food Safety and Environmental Protection.	Ciuca VC, Rusanescu CO, Safta VV.	Pharmaceuticals (Basel)	10.3390/ph16030387	2023
	Detection of Actinobacillus pleuropneumoniae in pigs by real-time quantitative PCR for the apxIVA gene.	Tobias TJ, Bouma A, Klinkenberg D, Daemen AJ, Stegeman JA, Wagenaar JA, Duim B.	Vet J	10.1016/j.tvjl.2012.02.004	2012
Pathogenicity	Bacillus velezensis HBXN2020 alleviates Salmonella Typhimurium infection in mice by improving intestinal barrier integrity and reducing inflammation.	Wang L, Wang H, Li X, Zhu M, Gao D, Hu D, Xiong Z, Li X, Qian P.	Elife	10.7554/elife.93423	2024
Genetics	Is ICE hot? A genomic comparative study reveals integrative and conjugative elements as "hot" vectors for the dissemination of antibiotic resistance genes.	Zheng Q, Li L, Yin X, Che Y, Zhang T.	mSystems	10.1128/msystems.00178-23	2023
Metabolism	Expression of leucocyte function-associated antigen-1 and intercellular adhesion molecule-1 in the lungs of pigs infected with Actinobacillus pleuropneumoniae.	Oh Y, Ha Y, Han K, Seo HW, Kang I, Park C, Kim SC, Kim SH, Chae C.	J Comp Pathol	10.1016/j.jcpa.2012.06.002	2013
	Survey of porcine respiratory disease complex-associated pathogens among commercial pig farms in Korea via oral fluid method.	Cheong Y, Oh C, Lee K, Cho KH.	J Vet Sci	10.4142/jvs.2017.18.3.283	2017
	Development of a new multiplex quantitative PCR for the detection of Glaesserella parasuis, Mycoplasma hyorhinis, and Mycoplasma hyosynoviae.	Scherrer S, Schmitt S, Rademacher F, Kuhnert P, Ghielmetti G, Peterhans S, Stephan R.	Microbiologyopen	10.1002/mbo3.1353	2023
	Pharmacokinetic/Pharmacodynamic Integration to Evaluate the Changes in Susceptibility of Actinobacillus pleuropneumoniae After Repeated Administration of Danofloxacin.	Zhang L, Kang Z, Yao L, Gu X, Huang Z, Cai Q, Shen X, Ding H.	Front Microbiol	10.3389/fmicb.2018.02445	2018
	Evaluation of serovar-independent ELISA antigens of Actinobacillus pleuropneumoniae in pigs following vaccination or experimental challenge with respiratory pathogens and natural A. pleuropneumoniae serovar 1 challenge.	Eamens GJ, Gonsalves JR, Whittington AM, Turner B.	Aust Vet J	10.1111/j.1751-0813.2012.01008.x	2012
	The Effect of Inactivated Mycobacterium Paratuberculosis Vaccine on the Response to a Heterologous Bacterial Challenge in Pigs.	Jensen KJ, Hansen MS, Heegaard PMH, Benn CS, Jungersen G.	Front Immunol	10.3389/fimmu.2019.01557	2019
Metabolism	Actinobacillus utilizes a binding protein-dependent ABC transporter to acquire the active form of vitamin B₆.	Pan C, Zimmer A, Shah M, Huynh MS, Lai CC, Sit B, Hooda Y, Curran DM, Moraes TF.	J Biol Chem	10.1016/j.jbc.2021.101046	2021
Enzymology	Evaluation of diagnostic assays for the serological detection of Actinobacillus pleuropneumoniae on samples of known or unknown exposure.	Opriessnig T, Hemann M, Johnson JK, Heinen S, Gimenez-Lirola LG, O'Neill KC, Hoang H, Yoon KJ, Gottschalk M, Halbur PG.	J Vet Diagn Invest	10.1177/1040638712469607	2013
	Development and evaluation of a bead-based Multiplexed Fluorescent ImmunoAssay (MFIA) for detection of antibodies to Salmonella enterica serogroup B and C₁ in pigs.	Berger SS, Riber U, Jensen VF, Lauritsen KT, Andresen LO.	BMC Vet Res	10.1186/s12917-022-03362-w	2022
	Basic Characterization of Natural Transformation in Avibacterium paragallinarum.	Liu D, Zhang H, Tan H, Jin Y, Zhang C, Bo Z, Zhang X, Guo M, Wu Y.	Microbiol Spectr	10.1128/spectrum.05209-22	2023
	Nasal immunization with major epitope-containing ApxIIA toxin fragment induces protective immunity against challenge infection with Actinobacillus pleuropneumoniae in a murine model.	Seo KW, Kim SH, Park J, Son Y, Yoo HS, Lee KY, Jang YS.	Vet Immunol Immunopathol	10.1016/j.vetimm.2012.10.011	2013
	Thymol and carvacrol against Klebsiella: anti-bacterial, anti-biofilm, and synergistic activities-a systematic review.	Farhadi K, Rajabi E, Varpaei HA, Iranzadasl M, Khodaparast S, Salehi M.	Front Pharmacol	10.3389/fphar.2024.1487083	2024
	Incorporation of Actinobacillus pleuropneumoniae in Preformed Biofilms by Escherichia coli Isolated From Drinking Water of Swine Farms.	Ramirez-Castillo FY, Loera-Muro A, Vargas-Padilla ND, Moreno-Flores AC, Avelar-Gonzalez FJ, Harel J, Jacques M, Oropeza R, Barajas-Garcia CC, Guerrero-Barrera AL.	Front Vet Sci	10.3389/fvets.2018.00184	2018
	Assessment of animal diseases caused by bacteria resistant to antimicrobials: Swine.	EFSA Panel on Animal Health and Welfare (AHAW), Nielsen SS, Bicout DJ, Calistri P, Canali E, Drewe JA, Garin-Bastuji B, Gonzales Rojas JL, Gortazar Schmidt C, Herskin M, Michel V, Miranda Chueca MA, Padalino B, Pasquali P, Roberts HC, Sihvonen LH, Spoolder H, Stahl K, Velarde A, Viltrop A, Winckler C, Dewulf J, Guardabassi L, Hilbert F, Mader R, Baldinelli F, Alvarez J.	EFSA J	10.2903/j.efsa.2021.7113	2021
	In-feed nutritional additive probiotic Saccharomyces boulardii RC009 can substitute for prophylactic antibiotics and improve the production and health of weaning pigs.	Parada J, Magnoli A, Isgro MC, Poloni V, Fochesato A, Martinez MP, Carranza A, Cavaglieri L.	Vet World	10.14202/vetworld.2023.1035-1042	2023
	The Two-Component System CpxRA Affects Antibiotic Susceptibility and Biofilm Formation in Avian Pathogenic Escherichia coli.	Ma K, Wang H, Lv Z, Hu Y, Wang H, Shu F, Zhu C, Xue T.	Animals (Basel)	10.3390/ani13030383	2023
	Induction of protective immune responses against challenge of Actinobacillus pleuropneumoniae by oral administration with Saccharomyces cerevisiae expressing Apx toxins in pigs.	Shin MK, Kang ML, Jung MH, Cha SB, Lee WJ, Kim JM, Kim DH, Yoo HS.	Vet Immunol Immunopathol	10.1016/j.vetimm.2012.11.003	2013
Metabolism	Link between Heterotrophic Carbon Fixation and Virulence in the Porcine Lung Pathogen Actinobacillus pleuropneumoniae.	Konze SA, Abraham WR, Goethe E, Surges E, Kuypers MMM, Hoeltig D, Meens J, Vogel C, Stiesch M, Valentin-Weigand P, Gerlach GF, Buettner FFR.	Infect Immun	10.1128/iai.00768-18	2019
	Airborne transmission of common swine viruses.	Hu Z, Tian X, Lai R, Ji C, Li X.	Porcine Health Manag	10.1186/s40813-023-00346-6	2023
	Objective pathogen monitoring in nursery and finisher pigs by monthly laboratory diagnostic testing.	Goecke NB, Kobbero M, Kusk TK, Hjulsager CK, Pedersen KS, Kristensen CS, Larsen LE.	Porcine Health Manag	10.1186/s40813-020-00161-3	2020
	Evaluation of the predictive value of tonsil examination by bacteriological culture for detecting positive lung colonization status of nursery pigs exposed to Actinobacillus pleuropneumoniae by experimental aerosol infection.	Hoeltig D, Nietfeld F, Strutzberg-Minder K, Rohde J.	BMC Vet Res	10.1186/s12917-018-1542-9	2018
	Antimicrobial susceptibility monitoring of respiratory tract pathogens isolated from diseased cattle and pigs across Europe: the VetPath study.	de Jong A, Thomas V, Simjee S, Moyaert H, El Garch F, Maher K, Morrissey I, Butty P, Klein U, Marion H, Rigaut D, Valle M.	Vet Microbiol	10.1016/j.vetmic.2014.04.008	2014
	HipA-Mediated Phosphorylation of SeqA Does not Affect Replication Initiation in Escherichia coli.	Riber L, Koch BM, Kruse LR, Germain E, Lobner-Olesen A.	Front Microbiol	10.3389/fmicb.2018.02637	2018
Metabolism	Immunoproteomic analyses of outer membrane antigens of Actinobacillus pleuropneumoniae grown under iron-restricted conditions.	Chung JW, Kuster-Schock E, Gibbs BF, Jacques M, Coulton JW.	Vet Microbiol	10.1016/j.vetmic.2012.03.038	2012
	Development of a non-biased, high-throughput ELISA for the rapid evaluation of immunogenicity and cross-reactivity.	Fegan JE, Yu RH, Islam EA, Schryvers AB.	J Immunol Methods	10.1016/j.jim.2021.113037	2021
	Nanomaterial Adjuvants for Veterinary Vaccines: Mechanisms and Applications.	He L, Pan R, Liang R, Li B, Zhang P, He S, Li B, Li Y.	Research (Wash D C)	10.34133/research.0761	2025
	Toxigenic Vibrio cholerae strains in South-East Queensland, Australian river waterways.	Bhandari M, Rathnayake IU, Ariotti L, Heron B, Huygens F, Sullivan M, Jennison AV.	Appl Environ Microbiol	10.1128/aem.00472-23	2023
	Polymorphism analysis of the apxIA gene of Actinobacillus pleuropneumoniae serovar 5 isolated in swine herds from Brazil.	Dos Santos LF, Costa Polveiro R, Scatamburlo Moreira T, Pereira Vidigal PM, Chang YF, Scatamburlo Moreira MA.	PLoS One	10.1371/journal.pone.0208789	2018
	Molecular characterization of Streptococcus suis isolates recovered from diseased pigs in Europe.	Li K, Lacouture S, Lewandowski E, Thibault E, Gantelet H, Gottschalk M, Fittipaldi N.	Vet Res	10.1186/s13567-024-01366-y	2024
	Serotypes, virulence factors and multilocus sequence typing of Glaesserella parasuis from diseased pigs in Taiwan.	Wu CF, Hsu CY, Chou CC, Wang CM, Huang SW, Kuo HC.	PeerJ	10.7717/peerj.15823	2023
	Evaluation of serovar-independent ELISA antigens of Actinobacillus pleuropneumoniae in pigs, following experimental challenge with A. pleuropneumoniae, Mycoplasma hyopneumoniae and Pasteurella multocida.	Eamens GJ, Gonsalves JR, Whittington AM, Turner B.	Aust Vet J	10.1111/j.1751-0813.2012.00934.x	2012
Metabolism	Rapid and simple detection of Glaesserella parasuis in synovial fluid by recombinase polymerase amplification and lateral flow strip.	Zhang TT, Liu MZ, Yin RH, Yao LQ, Liu BS, Chen ZL.	BMC Vet Res	10.1186/s12917-019-2039-x	2019
Phylogeny	A Unique Capsule Locus in the Newly Designated Actinobacillus pleuropneumoniae Serovar 16 and Development of a Diagnostic PCR Assay.	Bosse JT, Li Y, Sarkozi R, Gottschalk M, Angen O, Nedbalcova K, Rycroft AN, Fodor L, Langford PR.	J Clin Microbiol	10.1128/jcm.02166-16	2017
Phylogeny	Proposal of serovars 17 and 18 of Actinobacillus pleuropneumoniae based on serological and genotypic analysis.	Bosse JT, Li Y, Sarkozi R, Fodor L, Lacouture S, Gottschalk M, Casas Amoribieta M, Angen O, Nedbalcova K, Holden MTG, Maskell DJ, Tucker AW, Wren BW, Rycroft AN, Langford PR, BRaDP1T consortium.	Vet Microbiol	10.1016/j.vetmic.2018.02.019	2018
Phylogeny	An atypical biotype I Actinobacillus pleuropneumoniae serotype 13 is present in North America.	Perry MB, Angen O, MacLean LL, Lacouture S, Kokotovic B, Gottschalk M.	Vet Microbiol	10.1016/j.vetmic.2011.11.024	2012
	Association between Enzootic Pneumonia-like Lung Lesions and Carcass Quality and Meat pH Value in Slaughter Pigs.	Przyborowska-Zhalniarovich P, Maes D, Otrocka-Domagala I, Pazdzior-Czapula K, Wiszniewska-Laszczych A, Soltysiuk M.	Animals (Basel)	10.3390/ani13132210	2023
	Magnetic beads-based enzymatic spectrofluorometric assay for rapid and sensitive detection of antibody against ApxIVA of Actinobacillus pleuropneumoniae.	Wei B, Li F, Yang H, Yu L, Zhao K, Zhou R, Hu Y.	Biosens Bioelectron	10.1016/j.bios.2012.03.027	2012
	Role of biofilms in antimicrobial resistance of the bacterial bovine respiratory disease complex.	Andres-Lasheras S, Zaheer R, Jelinski M, McAllister TA.	Front Vet Sci	10.3389/fvets.2024.1353551	2024
	Influences of ORF1 on the virulence and immunogenicity of Actinobacillus pleuropneumoniae.	Yuan F, Liu J, Guo Y, Tan C, Fu S, Zhao J, Chen H, Bei W.	Curr Microbiol	10.1007/s00284-011-0016-0	2011
Pathogenicity	Antimicrobial susceptibilities and resistance genes of Canadian isolates of Actinobacillus pleuropneumoniae.	Archambault M, Harel J, Goure J, Tremblay YD, Jacques M.	Microb Drug Resist	10.1089/mdr.2011.0150	2012
	Acanthamoeba castellanii Genotype T4: Inhibition of Proteases Activity and Cytopathic Effect by Bovine Apo-Lactoferrin.	Ramirez-Rico G, Martinez-Castillo M, Cardenas-Zuniga R, Coronado-Velazquez D, Silva-Olivares A, De la Garza M, Shibayama M, Serrano-Luna J.	Microorganisms	10.3390/microorganisms11030708	2023
Pathogenicity	Antimicrobial resistance of Actinobacillus pleuropneumoniae isolated from swine.	Vanni M, Merenda M, Barigazzi G, Garbarino C, Luppi A, Tognetti R, Intorre L.	Vet Microbiol	10.1016/j.vetmic.2011.10.022	2012
Pathogenicity	The Antimicrobial Peptide MPX Can Kill Staphylococcus aureus, Reduce Biofilm Formation, and Effectively Treat Bacterial Skin Infections in Mice.	Zhu C, Zhao Y, Zhao X, Liu S, Xia X, Zhang S, Wang Y, Zhang H, Xu Y, Chen S, Jiang J, Wu Y, Wu X, Zhang G, Bai Y, Hu J, Fotina H, Wang L, Zhang X.	Front Vet Sci	10.3389/fvets.2022.819921	2022
	The Role of luxS in Histophilus somni Virulence and Biofilm Formation.	Pan Y, Siddaramappa S, Sandal I, Dickerman A, Bandara AB, Inzana TJ.	Infect Immun	10.1128/iai.00567-20	2021
	The genetic analysis of the flp locus of Actinobacillus pleuropneumoniae.	Li T, Xu Z, Zhang T, Li L, Chen H, Zhou R.	Arch Microbiol	10.1007/s00203-011-0741-6	2012
	Glycoproteomics and Its Role in Understanding Bacterial O-Linked Glycosylation.	Karlic KI, Tahir H, Scott NE.	Proteomics	10.1002/pmic.202400256	2025
	Survey for selected pathogens in wild pigs (Sus scrofa) from Guam, Marianna Islands, USA.	Cleveland CA, DeNicola A, Dubey JP, Hill DE, Berghaus RD, Yabsley MJ.	Vet Microbiol	10.1016/j.vetmic.2017.05.001	2017
	Florfenicol administration in piglets co-selects for multiple antimicrobial resistance genes.	Holman DB, Gzyl KE, Kommadath A.	mSystems	10.1128/msystems.01250-24	2024
	Visualization and application of disease diagnosis codes for population health management using porcine diseases as a model.	Trevisan G, Schwartz KJ, Burrough ER, Arruda B, Derscheid RJ, Rahe MC, Magalhaes ES, Almeida MN, Main RG, Linhares DCL.	J Vet Diagn Invest	10.1177/1040638721995782	2021
Pathogenicity	microRNA maintains nutrient homeostasis in the symbiont-host interaction.	Shang F, Ding BY, Niu J, Lu JM, Xie XC, Li CZ, Zhang W, Pan D, Jiang RX, Wang JJ.	Proc Natl Acad Sci U S A	10.1073/pnas.2406925121	2024
Phylogeny	High-throughput screening for respiratory pathogens within pigs in Denmark; analysis of circulating porcine respiratory coronaviruses and their association with other pathogens.	Bedsted AE, Goecke NB, Hjulsager CK, Ryt-Hansen P, Larsen KC, Rasmussen TB, Botner A, Larsen LE, Belsham GJ.	Virus Res	10.1016/j.virusres.2024.199501	2024
	A retrospective study of equine actinobacillosis cases: 1999-2011.	Layman QD, Rezabek GB, Ramachandran A, Love BC, Confer AW.	J Vet Diagn Invest	10.1177/1040638714531766	2014
Metabolism	Apa is a trimeric autotransporter adhesin of Actinobacillus pleuropneumoniae responsible for autoagglutination and host cell adherence.	Xiao L, Zhou L, Sun C, Feng X, Du C, Gao Y, Ji Q, Yang S, Wang Y, Han W, Langford PR, Lei L.	J Basic Microbiol	10.1002/jobm.201100365	2012
	How does Quorum Sensing of Intestinal Bacteria Affect Our Health and Mental Status?	Dicks LMT.	Microorganisms	10.3390/microorganisms10101969	2022
Metabolism	Global Gene Networks in 3D4/31 Porcine Alveolar Macrophages Treated with Antigenic Epitopes of Actinobacillus pleuropneumoniae ApxIA, IIA, and IVA.	Kim S, Oh MW, Bin Park W, Yoo HS.	Sci Rep	10.1038/s41598-019-41748-3	2019
	Predicting genetic traits and epitope analysis of apxIVA in Actinobacillus pleuropneumoniae.	Shin MK, Cha SB, Lee WJ, Yoo HS.	J Microbiol	10.1007/s12275-011-0449-y	2011
	Evaluation of the clinical efficacy of a water soluble formulation of tylvalosin in the control of enzootic pneumonia associated with Mycoplasma hyopneumoniae and Pasteurella multocida in pigs.	Lopez Rodriguez A, Berge AC, Ramage C, Saltzman R, Domangue RJ, Gnozzio MJ, Muller A, Sierra P, Benchaoui HA.	Porcine Health Manag	10.1186/s40813-020-00177-9	2020
	A Comparative Field Evaluation of the Effect of Growth Performance Between Porcine Circovirus Type 2a (PCV2a)- and PCV2b-Based Bivalent Vaccines Containing PCV2 and Mycoplasma hyopneumoniae.	Cho H, Oh T, Suh J, Chae C.	Front Vet Sci	10.3389/fvets.2022.859344	2022
Pathogenicity	Antimicrobial resistance in bacteria associated with porcine respiratory disease in Australia.	Dayao DA, Gibson JS, Blackall PJ, Turni C.	Vet Microbiol	10.1016/j.vetmic.2014.03.014	2014
	A new variant of Actinobacillus pleuropneumoniae serotype 3 lacking the entire apxII operon.	Kuhnert P, Rohde J, Korczak BM.	J Vet Diagn Invest	10.1177/1040638711404148	2011
	Deciphering complex antibiotic resistance patterns in Helicobacter pylori through whole genome sequencing and machine learning.	Yu J, Jia Y, Yu Q, Lin L, Li C, Chen B, Zhong P, Lin X, Li H, Sun Y, Zhong X, He Y, Huang X, Lin S, Pan Y.	Front Cell Infect Microbiol	10.3389/fcimb.2023.1306368	2023
	In vivo testing of novel vaccine prototypes against Actinobacillus pleuropneumoniae.	Antenucci F, Fougeroux C, Deeney A, Orskov C, Rycroft A, Holst PJ, Bojesen AM.	Vet Res	10.1186/s13567-017-0502-x	2018
Pathogenicity	Determination of minimum inhibitory and minimum bactericidal concentrations of tiamulin against field isolates of Actinobacillus pleuropneumoniae.	Pridmore A, Burch D, Lees P.	Vet Microbiol	10.1016/j.vetmic.2011.03.016	2011
	The lipopolysaccharide core of Actinobacillus suis and its relationship to those of Actinobacillus pleuropneumoniae.	Ganeshapillai J, Boncheff AG, Slavic D, MacInnes J, Monteiro MA.	Biochem Cell Biol	10.1139/o11-003	2011
Metabolism	Comparison of three typing assays for nicotinamide adenine dinucleotide-independent Actinobacillus pleuropneumoniae.	Maldonado J, Blanco M, Martinez E, Navas J.	J Vet Diagn Invest	10.1177/1040638711407895	2011
	Identifying miRNA-mRNA regulatory networks on extreme n-6/n-3 polyunsaturated fatty acid ratio expression profiles in porcine skeletal muscle.	Manaig YJY, Criado-Mesas L, Esteve-Codina A, Marmol-Sanchez E, Castello A, Sanchez A, Folch JM.	PLoS One	10.1371/journal.pone.0283231	2023
	DNA vaccine encoding type IV pilin of Actinobacillus pleuropneumoniae induces strong immune response but confers limited protective efficacy against serotype 2 challenge.	Lu YC, Li MC, Chen YM, Chu CY, Lin SF, Yang WJ.	Vaccine	10.1016/j.vaccine.2011.07.127	2011
	Comparative Genomics of the First and Complete Genome of "Actinobacillus porcitonsillarum" Supports the Novel Species Hypothesis.	Dona V, Perreten V.	Int J Genomics	10.1155/2018/5261719	2018
Genetics	Genomic differences between Actinobacillus pleuropneumoniae serotypes 5b and 3 and their distribution and transcription among 15 serotypes.	Yang F, Xie F, Jiang Y, Li S, Xing Y, Wang Y, Feng X, Han W, Lei L.	Curr Microbiol	10.1007/s00284-011-9986-1	2011
	Ubiquitous influenza A virus in Chilean swine before the H1N1pdm09 introduction.	Mena J, Ariyama N, Navarro C, Quezada M, Brevis C, Rojas D, Medina RA, Brito B, Ruiz A, Neira V.	Transbound Emerg Dis	10.1111/tbed.14243	2021
	A Conserved Stem-Loop Structure within ORF5 Is a Frequent Recombination Hotspot for Porcine Reproductive and Respiratory Syndrome Virus 1 (PRRSV-1) with a Particular Modified Live Virus (MLV) Strain.	Motz M, Stadler J, Kreutzmann H, Ladinig A, Lamp B, Auer A, Riedel C, Rumenapf T.	Viruses	10.3390/v15010258	2023
	Regulatory functional role of NLRP3 inflammasome during Mycoplasma hyopneumoniae infection in swine.	Zhang Y, Liu B, Said A, Xie J, Tian F, Cao Z, Chao Z, Li F, Li X, Li S, Liu H, Wang W.	J Anim Sci	10.1093/jas/skad216	2023
	Solid Lipid Nanoparticles for Duodenum Targeted Oral Delivery of Tilmicosin.	Zhou K, Yan Y, Chen D, Huang L, Li C, Meng K, Wang S, Algharib SA, Yuan Z, Xie S.	Pharmaceutics	10.3390/pharmaceutics12080731	2020
	Genetic variability in swine leukocyte antigen class II and Toll-like receptors affects immune responses to vaccination for bacterial infections in pigs.	Shinkai H, Arakawa A, Tanaka-Matsuda M, Ide-Okumura H, Terada K, Chikyu M, Kawarasaki T, Ando A, Uenishi H.	Comp Immunol Microbiol Infect Dis	10.1016/j.cimid.2012.05.003	2012
	What is the true in vitro potency of oxytetracycline for the pig pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida?	Dorey L, Hobson S, Lees P.	J Vet Pharmacol Ther	10.1111/jvp.12386	2017
	The two-component system CpxA/CpxR regulates pathogenesis and stress adaptability in the poplar canker bacterium Lonsdalea populi.	Yang R, Ming Z, Zeng S, Wang Y, Wang Y, Li A.	Mol Plant Pathol	10.1111/mpp.70029	2024
Pathogenicity	Antimicrobial susceptibility of Actinobacillus pleuropneumoniae isolates from clinical outbreaks of porcine respiratory diseases.	Kucerova Z, Hradecka H, Nechvatalova K, Nedbalcova K.	Vet Microbiol	10.1016/j.vetmic.2011.01.016	2011
Enzymology	Gamithromycin in swine: Pharmacokinetics and clinical evaluation against swine respiratory disease.	Hamel D, Richard-Mazet A, Voisin F, Bohne I, Fraisse F, Rauh R, Huang R, Kellermann M, Letendre L, Dumont P, Rehbein S.	Vet Med Sci	10.1002/vms3.375	2021
Metabolism	Expression of secreted mucins (MUC2, MUC5AC, MUC5B, and MUC6) and membrane-bound mucin (MUC4) in the lungs of pigs experimentally infected with Actinobacillus pleuropneumoniae.	Kim CH, Oh Y, Han K, Seo HW, Kim D, Kang I, Park C, Jang KY, Kim SH, Chae C.	Res Vet Sci	10.1016/j.rvsc.2011.04.016	2012
Enzymology	Occurrence and severity of lung lesions in slaughter pigs vaccinated against Mycoplasma hyopneumoniae with different strategies.	Hillen S, von Berg S, Kohler K, Reinacher M, Willems H, Reiner G.	Prev Vet Med	10.1016/j.prevetmed.2013.12.012	2014
Enzymology	Multiplex PCR assay for detection of Actinobacillus pleuropneumoniae, Pasteurella multocida and Haemophilus parasuis in lungs of pigs from a slaughterhouse.	Hricinova M, Holoda E, Mudronova D, Ondrasovicova S.	Folia Microbiol (Praha)	10.1007/s12223-010-0103-9	2010
Transcriptome	Draft genome sequence of Actinobacillus pleuropneumoniae serotype 7 strain S-8.	Li G, Xie F, Zhang Y, Wang C.	J Bacteriol	10.1128/jb.01650-12	2012
	The exploration of anti-Vibrio parahaemolyticus substances from Phellodendri Chinensis Cortex as a preservative for shrimp storage.	Zheng H, Liu Y, Cai J, Zhang M, Wen Y, Guo L.	Front Microbiol	10.3389/fmicb.2022.1004262	2022
Metabolism	An immunosorbent assay based on the recombinant ApxIa, ApxIIa, and ApxIIIa toxins of Actinobacillus pleuropneumoniae and its application to field sera.	Shin MK, Kang ML, Cha SB, Lee WJ, Sung JH, Yoo HS.	J Vet Diagn Invest	10.1177/1040638711407889	2011
	Unweaving tangled mortality and antibiotic consumption data to detect disease outbreaks - Peaks, growths, and foresight in swine production.	Lopes Antunes AC, Jensen VF, Jensen D.	PLoS One	10.1371/journal.pone.0223250	2019
	Agonic Aspiration of Blood: Not Useful as an Animal-Based Indicator of Electrical Stunning Ineffectiveness in Pigs (Sus scrofa domesticus).	Ferreira MF, Fabrega E, Pires I, Vieira-Pinto MM.	Animals (Basel)	10.3390/ani13142292	2023
	Susceptibility of caprine mastitis pathogens to tildipirosin, gamithromycin, oxytetracycline, and danofloxacin: effect of serum on the in vitro potency of current macrolides.	Galecio JS, Escudero E, Corrales JC, Garcia-Romero E, de la Fe C, Hernandis V, Marin P.	World J Microbiol Biotechnol	10.1007/s11274-022-03407-0	2022
Transcriptome	A Transcriptome Map of Actinobacillus pleuropneumoniae at Single-Nucleotide Resolution Using Deep RNA-Seq.	Su Z, Zhu J, Xu Z, Xiao R, Zhou R, Li L, Chen H.	PLoS One	10.1371/journal.pone.0152363	2016
	Pharmacokinetics and Pharmacodynamics of Florfenicol in Plasma and Synovial Fluid of Pigs at a Dose of 30 mg/kg_bw Following Intramuscular Administration.	Somogyi Z, Mag P, Simon R, Kerek A, Szabo P, Albert E, Biksi I, Jerzsele A.	Antibiotics (Basel)	10.3390/antibiotics12040758	2023
	Molecular characterization of porcine reproductive and respiratory syndrome virus (PRRSv) identified from slaughtered pigs in northern Uganda.	Oba P, Dione MM, Erume J, Wieland B, Mutisya C, Ochieng L, Cook EAJ, Mwiine FN.	BMC Vet Res	10.1186/s12917-022-03272-x	2022
	Improvement of technical results following use of Ingelvac CircoFLEX in a Dutch organic breeding and fattening farm: a case report.	Schlepers M, Gelauf J, Wertenbroek N, Nielen M.	Tijdschr Diergeneeskd		2013
	Effects of different antimicrobial treatments on serum acute phase responses and leucocyte counts in pigs after a primary and a secondary challenge infection with Actinobacillus pleuropneumoniae.	Sjolund M, Fossum C, Martin de la Fuente AJ, Alava M, Juul-Madsen HR, Lampreave F, Wallgren P.	Vet Rec	10.1136/vr.d2268	2011
	A secreted bacterial protein protects bacteria from cationic antimicrobial peptides by entrapment in phase-separated droplets.	Ostan NKH, Cole GB, Wang FZ, Reichheld SE, Moore G, Pan C, Yu R, Lai CC, Sharpe S, Lee HO, Schryvers AB, Moraes TF.	PNAS Nexus	10.1093/pnasnexus/pgae139	2024
	Metataxonomic and metaproteomic profiling of the oral microbiome in oral lichen planus - a pilot study.	Bankvall M, Carda-Dieguez M, Mira A, Karlsson A, Hasseus B, Karlsson R, Robledo-Sierra J.	J Oral Microbiol	10.1080/20002297.2022.2161726	2023
Pathogenicity	Actinobacillus pleuropneumoniae is impaired by the garlic volatile allyl methyl sulfide (AMS) in vitro and in-feed garlic alleviates pleuropneumonia in a pig model.	Becker PM, van Wikselaar PG, Mul MF, Pol A, Engel B, Wijdenes JW, van der Peet-Schwering CM, Wisselink HJ, Stockhofe-Zurwieden N.	Vet Microbiol	10.1016/j.vetmic.2011.07.011	2012
Enzymology	Tissue distribution of marbofloxacin in pigs after a single intramuscular injection.	Yang F, Liu Y, Li Z, Wang Y, Liu B, Zhao Z, Zhou B, Wang G.	J Vet Sci	10.4142/jvs.2017.18.2.169	2017
Genetics	Whole Genome Sequencing for Surveillance of Antimicrobial Resistance in Actinobacillus pleuropneumoniae.	Bosse JT, Li Y, Rogers J, Fernandez Crespo R, Li Y, Chaudhuri RR, Holden MT, Maskell DJ, Tucker AW, Wren BW, Rycroft AN, Langford PR.	Front Microbiol	10.3389/fmicb.2017.00311	2017
	Evidence of Horse Exposure to Anaplasma phagocytophilum, Borrelia burgdorferi, and Leishmania infantum in Greece through the Detection of IgG Antibodies in Serum and in an Alternative Diagnostic Sample-The Saliva.	Athanasiou LV, Katsogiannou EG, Tyrnenopoulou P, Gougoulis D, Apostolidis KN, Papadakis SM, Kokkinaki KCG, Papatsiros VG, Tsokana CN.	Biomolecules	10.3390/biom13091374	2023
Metabolism	A trivalent Apx-fusion protein delivered by E. coli outer membrane vesicles induce protection against Actinobacillus pleuropneumoniae of serotype 1 and 7 challenge in a murine model.	Xu K, Zhao Q, Wen X, Wu R, Wen Y, Huang X, Huang Y, Yan Q, Han X, Ma X, Chang YF, Cao S.	PLoS One	10.1371/journal.pone.0191286	2018
	Secretome Analysis of High- and Low-Virulent Bovine Pasteurella multocida Cultured in Different Media.	Qiu Y, Wang J, He F, Wu X, Dan R, Hardwidge PR, Li N, Peng Y.	Animals (Basel)	10.3390/ani13233683	2023
	Characterization of antigenic determinants in ApxIIA exotoxin capable of inducing protective immunity to Actinobacillus pleuropneumoniae challenge.	Seo KW, Kim DH, Kim AH, Yoo HS, Lee KY, Jang YS.	Immunol Invest	10.3109/08820139.2011.558151	2011
	Attenuated Actinobacillus pleuropneumoniae as a bacterial vector for expression of Mycoplasma hyopneumoniae P36 gene.	Zou HY, Liu XJ, Ma FY, Chen P, Zhou R, He QG.	J Gene Med	10.1002/jgm.1556	2011
Metabolism	Steric and allosteric factors prevent simultaneous binding of transferrin-binding proteins A and B to transferrin.	Silva LP, Yu RH, Calmettes C, Yang X, Moraes TF, Schriemer DC, Schryvers AB.	Biochem J	10.1042/bj20112133	2012
	Administration of poly[di(sodium carboxylatoethylphenoxy)]phosphazene (PCEP) as adjuvant activated mixed Th1/Th2 immune responses in pigs.	Dar A, Lai K, Dent D, Potter A, Gerdts V, Babiuk LA, Mutwiri GK.	Vet Immunol Immunopathol	10.1016/j.vetimm.2012.01.021	2012
	Novel genes associated with biofilm formation of Actinobacillus pleuropneumoniae.	Grasteau A, Tremblay YD, Labrie J, Jacques M.	Vet Microbiol	10.1016/j.vetmic.2011.03.029	2011
	Associations between animal and herd management factors, serological response to three respiratory pathogens and pluck lesions in finisher pigs on a farrow-to-finish farm.	Fitzgerald RM, O'Shea H, Manzanilla EG, Moriarty J, McGlynn H, Calderon Diaz JA.	Porcine Health Manag	10.1186/s40813-020-00173-z	2020
	Candidate genes and gene markers for the resistance to porcine pleuropneumonia.	Nietfeld F, Holtig D, Willems H, Valentin-Weigand P, Wurmser C, Waldmann KH, Fries R, Reiner G.	Mamm Genome	10.1007/s00335-019-09825-0	2020
	Chimeric vaccine design against the conserved TonB-dependent receptor-like beta-barrel domain from the outer membrane tbpA and hpuB proteins of Kingella kingae ATCC 23330.	Mashraqi MM, Alzamami A, Alturki NA, Almasaudi HH, Ahmed I, Alshamrani S, Basharat Z.	Front Mol Biosci	10.3389/fmolb.2023.1258834	2023
Metabolism	Analysis on Actinobacillus pleuropneumoniae LuxS regulated genes reveals pleiotropic roles of LuxS/AI-2 on biofilm formation, adhesion ability and iron metabolism.	Li L, Xu Z, Zhou Y, Li T, Sun L, Chen H, Zhou R.	Microb Pathog	10.1016/j.micpath.2011.02.002	2011
Metabolism	Mitogen-activated protein kinases p38 and JNK mediate Actinobacillus pleuropneumoniae exotoxin ApxI-induced apoptosis in porcine alveolar macrophages.	Wu CM, Chen ZW, Chen TH, Liao JW, Lin CC, Chien MS, Lee WC, Hsuan SL.	Vet Microbiol	10.1016/j.vetmic.2011.03.033	2011
	Effects of Core Antigen Bacterin with an Immunostimulant on Piglet Health and Performance Outcomes When Challenged with Enteric and Respiratory Pathogens.	Cull CA, Singu VK, Bromm JJ, Lechtenberg KF, Amachawadi RG, Cull BJ.	Antibiotics (Basel)	10.3390/antibiotics12030599	2023
	The Connection Between Stress and Immune Status in Pigs: A First Salivary Analytical Panel for Disease Differentiation.	Sanchez J, Matas M, Ibanez-Lopez FJ, Hernandez I, Sotillo J, Gutierrez AM.	Front Vet Sci	10.3389/fvets.2022.881435	2022
	Factors affecting performance response of pigs exposed to different challenge models: a multivariate approach.	Rodrigues LA, Ferreira FNA, Costa MO, Wellington MO, Columbus DA.	J Anim Sci	10.1093/jas/skab035	2021
	Safety Study on Ketoprofen in Pigs: Evaluating the Effects of Different Dosing and Treatment Scheme on Hematological, Hepatic, and Renal Parameters.	Fazzio LE, Raggio SJ, Romero JF, Membrebe J, Minervino AHH.	Vet Sci	10.3390/vetsci8020030	2021
	Removing prophylactic antibiotics from pig feed: how does it affect their performance and health?	Diana A, Boyle LA, Leonard FC, Carroll C, Sheehan E, Murphy D, Manzanilla EG.	BMC Vet Res	10.1186/s12917-019-1808-x	2019
Pathogenicity	Study of the Role of Lipoprotein Maturation Enzymes in the Pathogenesis of the Infection Caused by the Streptococcus suis Serotype 2 Sequence Type 25 North American Prototype Strain.	Payen S, Roy D, Okura M, Segura M, Gottschalk M.	Pathogens	10.3390/pathogens12111325	2023
	Development of a cps-based multiplex PCR for typing of Actinobacillus pleuropneumoniae serotypes 1, 2 and 5.	Ito H.	J Vet Med Sci	10.1292/jvms.09-0529	2010
	Added Value of Sensor-Based Behavioural Monitoring in an Infectious Disease Study with Sheep Infected with Toxoplasma gondii.	Doekes HP, Petie R, de Jong R, Adriaens I, Wisselink HJ, Stockhofe-Zurwieden N.	Animals (Basel)	10.3390/ani14131908	2024
Metabolism	Pharmacokinetics of tildipirosin in porcine plasma, lung tissue, and bronchial fluid and effects of test conditions on in vitro activity against reference strains and field isolates of Actinobacillus pleuropneumoniae.	Rose M, Menge M, Bohland C, Zschiesche E, Wilhelm C, Kilp S, Metz W, Allan M, Ropke R, Nurnberger M.	J Vet Pharmacol Ther	10.1111/j.1365-2885.2012.01397.x	2013
	A protein-based subunit vaccine with biological adjuvants provides effective protection against Pasteurella multocida in pigs.	Wu MC, Wu HC, Lee JW, Chang WC, Chu CY.	Vet Res	10.1186/s13567-023-01150-4	2023
	Virological Characterization of Pigs with Erythema Multiforme.	Halecker S, Papatsiros V, Psalla D, Krabben L, Kaufer B, Denner J.	Microorganisms	10.3390/microorganisms10030652	2022
	Comparison of different detection methods for Ascaris suum infection on Austrian swine farms.	Joachim A, Winkler C, Ruczizka U, Ladinig A, Koch M, Tichy A, Schwarz L.	Porcine Health Manag	10.1186/s40813-021-00236-9	2021
Pathogenicity	Antibiotic resistance in porcine pathogenic bacteria and relation to antibiotic usage.	Holmer I, Salomonsen CM, Jorsal SE, Astrup LB, Jensen VF, Hog BB, Pedersen K.	BMC Vet Res	10.1186/s12917-019-2162-8	2019
	Streptococcus equi subsp. zooepidemicus infection of pigs leads to shedding in faeces and a carrier state.	Costa MO, Harding JCS, Huang Y, Nosach R.	Transbound Emerg Dis	10.1111/tbed.14481	2022
	Dynamic Variations in Infrared Skin Temperature of Weaned Pigs Experimentally Inoculated with the African Swine Fever Virus: A Pilot Study.	Oh SI, Lee HS, Bui VN, Dao DT, Bui NA, Le TD, Kieu MA, Nguyen QH, Tran LH, So KM, Yi SW, Kim E, Hur TY.	Vet Sci	10.3390/vetsci8100223	2021
	Mycoplasma hyopneumoniae in free-living wild boars in Paraná, Brazil.	de Souza TCGD, Silva VS, Mores MAZ, Kramer B, Leme RA, da Silva Porto G, Alfieri AA.	Braz J Microbiol	10.1007/s42770-021-00516-0	2021
Enzymology	Prevalence of Actinobacillus pleuropneumoniae infection in hunted wild boars (Sus scrofa) in Germany.	Reiner G, Fresen C, Bronnert S, Haack I, Willems H.	J Wildl Dis	10.7589/0090-3558-46.2.551	2010
	African swine fever virus infection enhances CD14-dependent phagocytosis of porcine alveolar macrophages to promote bacterial uptake and apoptotic body-mediated viral transmission.	Shi F, Xu Z, Gao P, Qu Y, Ge X, Zhang Y, Han J, Guo X, Zhou L, Yang H.	J Virol	10.1128/jvi.00690-25	2025
	Cytoplasmic glycoengineering of Apx toxin fragments in the development of Actinobacillus pleuropneumoniae glycoconjugate vaccines.	Passmore IJ, Andrejeva A, Wren BW, Cuccui J.	BMC Vet Res	10.1186/s12917-018-1751-2	2019
	The generation of successive unmarked mutations and chromosomal insertion of heterologous genes in Actinobacillus pleuropneumoniae using natural transformation.	Bosse JT, Soares-Bazzolli DM, Li Y, Wren BW, Tucker AW, Maskell DJ, Rycroft AN, Langford PR, BRaDP1T Consortium.	PLoS One	10.1371/journal.pone.0111252	2014
	In Vitro Glycosylation of Membrane Proteins Using N-Glycosyltransferase.	Ahangama Liyanage L, Harris MS, Cook GA.	ACS Omega	10.1021/acsomega.1c00835	2021
	Establishment of a Mycoplasma hyorhinis challenge model in 5-week-old piglets.	Foldi D, Nagy ZE, Belecz N, Szeredi L, Foldi J, Kollar A, Tenk M, Kreizinger Z, Gyuranecz M.	Front Microbiol	10.3389/fmicb.2023.1209119	2023
	Disease patterns and immune responses in the offspring to sows with high or low antibody levels to Actinobacillus pleuropneumoniae serotype 2.	Sjolund M, Zoric M, Persson M, Karlsson G, Wallgren P.	Res Vet Sci	10.1016/j.rvsc.2010.07.025	2011
	Differences in the relative counts of peripheral blood lymphocyte subsets in various age groups of pigs.	Pietrasina O, Miller J, Rzasa A.	Can J Vet Res		2020
Enzymology	Evaluation of Actinobacillus pleuropneumoniae diagnostic tests using samples derived from experimentally infected pigs.	Costa G, Oliveira S, Torrison J, Dee S.	Vet Microbiol	10.1016/j.vetmic.2010.08.023	2011
	Characterisation of Pasteurella multocida isolates from pigs with pneumonia in Korea.	Kim J, Kim JW, Oh SI, So B, Kim WI, Kim HY.	BMC Vet Res	10.1186/s12917-019-1861-5	2019
Enzymology	Expression of matrix metalloproteinase-9 and -12 in porcine lung infections.	Bruun CS, Leifsson PS, Johansen LK, Jensen HE, Nielsen J, Fredholm M.	J Comp Pathol	10.1016/j.jcpa.2011.05.005	2012
Enzymology	Infectious agents associated with respiratory diseases in 125 farrow-to-finish pig herds: a cross-sectional study.	Fablet C, Marois-Crehan C, Simon G, Grasland B, Jestin A, Kobisch M, Madec F, Rose N.	Vet Microbiol	10.1016/j.vetmic.2011.12.015	2012
Genetics	A genome-wide screen for resilient responses in growing pigs.	Laghouaouta H, Fraile L, Suarez-Mesa R, Ros-Freixedes R, Estany J, Pena RN.	Genet Sel Evol	10.1186/s12711-022-00739-1	2022
	Sub-Inhibitory Concentrations of Amoxicillin and Tylosin Affect the Biofilm Formation and Virulence of Streptococcus suis.	Zuo J, Fan Q, Li J, Liu B, Xue B, Zhang X, Yi L, Wang Y.	Int J Environ Res Public Health	10.3390/ijerph19148359	2022
Pathogenicity	Zinc as an agent for the prevention of biofilm formation by pathogenic bacteria.	Wu C, Labrie J, Tremblay YD, Haine D, Mourez M, Jacques M.	J Appl Microbiol	10.1111/jam.12197	2013
	Surface-displayed expression of a neutralizing epitope of ApxIIA exotoxin in Saccharomyces cerevisiae and oral administration of it for protective immune responses against challenge by Actinobacillus pleuropneumoniae.	Kim JM, Jung DI, Eom YJ, Park SM, Yoo HS, Jang YS, Yang MS, Kim DH.	Biosci Biotechnol Biochem	10.1271/bbb.90941	2010
	Bovine apo-lactoferrin affects the secretion of proteases in Mannheimia haemolytica A2.	Ramirez-Rico G, Martinez-Castillo M, Avalos-Gomez C, de la Garza M.	Access Microbiol	10.1099/acmi.0.000269	2021
	Survey of pleuritis and pulmonary lesions in pigs at abattoir with a focus on the extent of the condition and herd risk factors.	Merialdi G, Dottori M, Bonilauri P, Luppi A, Gozio S, Pozzi P, Spaggiari B, Martelli P.	Vet J	10.1016/j.tvjl.2011.11.009	2012
Metabolism	Microbiome and oral squamous cell carcinoma: a possible interplay on iron metabolism and its impact on tumor microenvironment.	Arthur RA, Dos Santos Bezerra R, Ximenez JPB, Merlin BL, de Andrade Morraye R, Neto JV, Fava NMN, Figueiredo DLA, de Biagi CAO, Summer Course 2020 group, Montibeller MJ, Guimaraes JB, Alves EG, Schreiner M, da Costa TS, da Silva CFL, Malheiros JM, da Silva LHB, Ribas GT, Achallma DO, Braga CM, Andrade KFA, do Carmo Alves Martins V, Dos Santos GVN, Granatto CF, Terin UC, Sanches IH, Ramos DE, Garay-Malpartida HM, de Souza GMP, Slavov SN, Silva WA.	Braz J Microbiol	10.1007/s42770-021-00491-6	2021
	A novel portable Raman scattering platform for antibiotic screening in pig urine.	Wattanavichean N, Nimittrakoolchai OU, Nuntawong N, Horprathum M, Eiamchai P, Limwichean S, Somboonsaksri P, Sreta D, Meesuwan S.	Vet World	10.14202/vetworld.2023.204-214	2023
Pathogenicity	Proteomic and Antibody Profiles Reveal Antigenic Composition and Signatures of Bacterial Ghost Vaccine of Brucella abortus A19.	He CY, Yang JH, Ye YB, Zhao HL, Liu MZ, Yang QL, Liu BS, He S, Chen ZL.	Front Immunol	10.3389/fimmu.2022.874871	2022
	Skin-Based Vaccination: A Systematic Mapping Review of the Types of Vaccines and Methods Used and Immunity and Protection Elicited in Pigs.	Co-Rives I, Chen AY, Moore AC.	Vaccines (Basel)	10.3390/vaccines11020450	2023
Pathogenicity	Characterisation of a mobilisable plasmid conferring florfenicol and chloramphenicol resistance in Actinobacillus pleuropneumoniae.	Bosse JT, Li Y, Atherton TG, Walker S, Williamson SM, Rogers J, Chaudhuri RR, Weinert LA, Holden MT, Maskell DJ, Tucker AW, Wren BW, Rycroft AN, Langford PR, BRaDP1T consortium.	Vet Microbiol	10.1016/j.vetmic.2015.05.020	2015
	In vitro and in vivo Synergistic Effects of Florfenicol and Thiamphenicol in Combination Against Swine Actinobacillus pleuropneumoniae and Pasteurella multocida.	Rattanapanadda P, Kuo HC, Vickroy TW, Sung CH, Rairat T, Lin TL, Yeh SY, Chou CC.	Front Microbiol	10.3389/fmicb.2019.02430	2019
	Optimization of ultrasound-assisted extraction based on response surface methodology using HPLC-DAD for the analysis of red clover (Trifolium pretense L.) isoflavones and its anti-inflammatory activities on LPS-induced 3D4/2 cell.	Luo Z, Xu Y, Qiu L, Lv S, Zeng C, Tan A, Ou D, Song X, Yang J.	Front Vet Sci	10.3389/fvets.2023.1279178	2023
	The pharmacokinetics and pharmacodynamics of cefquinome against Streptococcus agalactiae in a murine mastitis model.	Yang Q, Zhang C, Liu X, Zhang L, Yong K, Lv Q, Zhang Y, Chen L, Zhong P, Liu Y.	PLoS One	10.1371/journal.pone.0278306	2023
	Single Multiple Cross Displacement Amplification for Rapid and Real-Time Detection of Porcine Circovirus 3.	Bian Z, Cai R, Jiang Z, Song S, Li Y, Chu P, Zhang K, Yang D, Gou H, Li C.	Front Vet Sci	10.3389/fvets.2021.726723	2021
Metabolism	The CpxA/CpxR Two-Component System Affects Biofilm Formation and Virulence in Actinobacillus pleuropneumoniae.	Li H, Liu F, Peng W, Yan K, Zhao H, Liu T, Cheng H, Chang P, Yuan F, Chen H, Bei W.	Front Cell Infect Microbiol	10.3389/fcimb.2018.00072	2018
	Development and Validation of a Loop-Mediated Isothermal Amplification (LAMP) Assay for Rapid Detection of Glaesserella (Haemophilus) parasuis.	Pilchova V, Seinige D, Hennig-Pauka I, Buttner K, Abdulmawjood A, Kehrenberg C.	Microorganisms	10.3390/microorganisms9010041	2020
	Immunoprotective Efficacy of Six In vivo-Induced Antigens against Actinobacillus pleuropneumoniae as Potential Vaccine Candidates in Murine Model.	Zhang F, Cao S, Zhu Z, Yang Y, Wen X, Chang YF, Huang X, Wu R, Wen Y, Yan Q, Huang Y, Ma X, Zhao Q.	Front Microbiol	10.3389/fmicb.2016.01623	2016
Pathogenicity	Characterization of the Actinobacillus pleuropneumoniae SXT-related integrative and conjugative element ICEApl2 and analysis of the encoded FloR protein: hydrophobic residues in transmembrane domains contribute dynamically to florfenicol and chloramphenicol efflux.	Li Y, Li Y, Fernandez Crespo R, Leanse LG, Langford PR, Bosse JT.	J Antimicrob Chemother	10.1093/jac/dkx342	2018
Pathogenicity	Effective Pro-Inflammatory Induced Activity of GALT, a Conserved Antigen in A. Pleuropneumoniae, Improves the Cytokines Secretion of Macrophage via p38, ERK1/2 and JNK MAPKs Signal Pathway.	Zhang F, Zhao Q, Tian J, Chang YF, Wen X, Huang X, Wu R, Wen Y, Yan Q, Huang Y, Ma X, Han X, Miao C, Cao S.	Front Cell Infect Microbiol	10.3389/fcimb.2018.00337	2018
	Prevalence and antimicrobial susceptibilities of bacterial pathogens in Chinese pig farms from 2013 to 2017.	Zhang B, Ku X, Yu X, Sun Q, Wu H, Chen F, Zhang X, Guo L, Tang X, He Q.	Sci Rep	10.1038/s41598-019-45482-8	2019
Pathogenicity	Pharmacokinetic/pharmacodynamic integration and modelling of oxytetracycline for the porcine pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida.	Dorey L, Pelligand L, Cheng Z, Lees P.	J Vet Pharmacol Ther	10.1111/jvp.12385	2017
Genetics	Comparative Genomic and Biological Investigation of NADC30- and NADC34-Like PRRSV Strains Isolated in South Korea.	Jeong H, Eo Y, Lee D, Jang G, Min KC, Choi AK, Won H, Cho J, Kang SC, Lee C.	Transbound Emerg Dis	10.1155/tbed/9015349	2025
	Effects of ClpP protease on biofilm formation of Enterococcus faecalis.	Feng Y, Wang H, Lu HE, Yi L, Hong LI.	J Appl Oral Sci	10.1590/1678-7757-2020-0733	2021
	Perturbation of Quorum Sensing after the Acquisition of Bacteriophage Resistance Could Contribute to Novel Traits in Vibrio alginolyticus.	Skliros D, Droubogiannis S, Kalloniati C, Katharios P, Flemetakis E.	Microorganisms	10.3390/microorganisms11092273	2023
	Update on the Mechanisms of Antibiotic Resistance and the Mobile Resistome in the Emerging Zoonotic Pathogen Streptococcus suis.	Dechene-Tempier M, Marois-Crehan C, Libante V, Jouy E, Leblond-Bourget N, Payot S.	Microorganisms	10.3390/microorganisms9081765	2021
	Response of lymphocytes from pigs naturally infected with porcine respiratory disease complex at 3 different stages of development.	Nunez-Anita RE, Calderon-Rico F, Perez-Duran F, Arenas-Arrocena MC, Zamora-Aviles AG, Franco-Correa LE, Bravo-Patino A, Hernandez-Morales I.	Can J Vet Res		2023
Phylogeny	Construction and characterization of an Actinobacillus pleuropneumoniae serotype 2 mutant lacking the Apx toxin secretion protein genes apxIIIB and apxIIID.	Park C, Ha Y, Kim S, Chae C, Ryu DY.	J Vet Med Sci	10.1292/jvms.001317	2009
	[Construction and characterization of Actinobacillus pleuropneumoniae serovar 7 live attenuated vaccine strain co-expressing ApxIA].	Liu J, Chen Y, Hu L, Bei W, Chen H.	Sheng Wu Gong Cheng Xue Bao		2010
	Comparative genomic analysis of two Arctic Pseudomonas strains reveals insights into the aerobic denitrification in cold environments.	Hu YQ, Zeng YX, Du Y, Zhao W, Li HR, Han W, Hu T, Luo W.	BMC Genomics	10.1186/s12864-023-09638-1	2023
Enzymology	Haemophilus parasuis serovars isolated from pathological samples in Northern Italy.	Luppi A, Bonilauri P, Dottori M, Iodice G, Gherpelli Y, Merialdi G, Maioli G, Martelli P.	Transbound Emerg Dis	10.1111/j.1865-1682.2012.01326.x	2013
	[Construction and characterization of an attenuate strain apxIC-/P36+ of Actinobacillus pleuropneumoniae serovar 10].	Zou H, Chen Y, Liu X, He Q, Chen P, Zhou R, Ma F, Wang Y.	Wei Sheng Wu Xue Bao		2009
	PK/PD integration of florfenicol alone and in combination with doxycycline against Riemerella anatipestifer.	Zhang H, Huang Y, Yu J, Liu X, Ding H.	Front Vet Sci	10.3389/fvets.2022.975673	2022
	Pharmacokinetic and Pharmacodynamic Evaluation of Marbofloxacin in Pig against Korean Local Isolates of Actinobacillus pleuropneumoniae.	Hossain MA, Park HC, Jeong K, Jang YH, Kim DG, Kang J, Lee KJ.	Biomed Res Int	10.1155/2017/2469826	2017
Genetics	A comparison of various feature extraction and machine learning methods for antimicrobial resistance prediction in streptococcus pneumoniae.	Kaya DE, Ulgen E, Kocagoz AS, Sezerman OU.	Front Antibiot	10.3389/frabi.2023.1126468	2023
	Prevalence of granulomatous pleuropneumonia associated with Actinobacillus pleuropneumoniae serotype 2 in slaughter pigs.	Ohba T, Shibahara T, Kobayashi H, Takashima A, Nagoshi M, Araki M, Takizawa K, Kubo M.	J Vet Med Sci	10.1292/jvms.71.1089	2009
	Isolation rates, serovars, and toxin genotypes of nicotinamide adenine dinucleotide-independent Actinobacillus pleuropneumoniae among pigs suffering from pleuropneumonia in Spain.	Maldonado J, Valls L, Martinez E, Riera P.	J Vet Diagn Invest	10.1177/104063870902100615	2009
	Differential gene expression in the pathogenic strains of Actinobacillus pleuropneumoniae serotypes 1 and 3.	Xie F, Zhang M, Li S, Du C, Sun C, Han W, Zhou L, Lei L.	J Microbiol Biotechnol	10.4014/jmb.0910.10040	2010
	Porcine Respiratory Coronavirus (PRCV): Isolation and Characterization of a Variant PRCV from USA Pigs.	Rawal G, Yim-Im W, Aljets E, Halbur PG, Zhang J, Opriessnig T.	Pathogens	10.3390/pathogens12091097	2023
Phylogeny	Genomic differences between Actinobacillus pleuropneumoniae serotypes 1 and 3 and the diversity distribution among 15 serotypes.	Xie F, Lei L, Du C, Li S, Han W, Ren Z.	FEMS Microbiol Lett	10.1111/j.1574-6968.2009.01870.x	2010
	Species comparison: human and minipig PBMC reactivity under the influence of immunomodulating compounds in vitro.	Pernold CPS, Lagumdzic E, Stadler M, Dolezal M, Jackel S, Schmitt MW, Mair KH, Saalmuller A.	Front Immunol	10.3389/fimmu.2023.1327776	2023
Enzymology	Rapid Purification of Endotoxin-Free RTX Toxins.	Stanek O, Masin J, Osicka R, Jurnecka D, Osickova A, Sebo P.	Toxins (Basel)	10.3390/toxins11060336	2019
	ISEc69-Mediated Mobilization of the Colistin Resistance Gene mcr-2 in Escherichia coli.	He YZ, Long TF, He B, Li XP, Li G, Chen L, Liao XP, Liu YH, Sun J.	Front Microbiol	10.3389/fmicb.2020.564973	2020
Transcriptome	Nitrate promotes the growth and the production of short-chain fatty acids and tryptophan from commensal anaerobe Veillonella dispar in the lactate-deficient environment by facilitating the catabolism of glutamate and aspartate.	Hung J-H, Zhang S-M, Huang S-L.	Appl Environ Microbiol	10.1128/aem.01148-24	2024
	ClpP protease modulates bacterial growth, stress response, and bacterial virulence in Brucella abortus.	Sun D, Liu Y, Peng X, Dong H, Jiang H, Fan X, Feng Y, Sun J, Han K, Gao Q, Niu J, Ding J.	Vet Res	10.1186/s13567-023-01200-x	2023
	Efficacy of bivalent vaccines of porcine circovirus type 2 and Mycoplasma hyopneumoniae in specific pathogen-free pigs challenged with porcine circovirus type 2d.	Lim J, Jin M, Yoon I, Yoo HS.	J Vet Sci	10.4142/jvs.21287	2022
	Advances in nanotechnology for the therapy of bacterial pneumonia	Tian Z, Zhang Y, Yun J, Kuang W, Li J.	Front Cell Infect Microbiol		2025
	Macrophage Polarization Modulated by Porcine Circovirus Type 2 Facilitates Bacterial Coinfection.	Zhang W, Fu Z, Yin H, Han Q, Fan W, Wang F, Shang Y.	Front Immunol	10.3389/fimmu.2021.688294	2021
Enzymology	Loop-mediated isothermal amplification targeting the apxIVA gene for detection of Actinobacillus pleuropneumoniae.	Yang W, Pin C, Haibing G, Yang C, Hui L, Qigai H.	FEMS Microbiol Lett	10.1111/j.1574-6968.2009.01779.x	2009
Pathogenicity	Responses of pigs to a re-challenge with Actinobacillus pleuropneumoniae after being treated with different antimicrobials following their initial exposure.	Sjolund M, de la Fuente AJ, Fossum C, Wallgren P.	Vet Rec	10.1136/vr.164.18.550	2009
Enzymology	On the possible roles of N-terminal His-rich domains of Cu,Zn SODs of some Gram-negative bacteria.	Arus D, Jancso A, Szunyogh D, Matyuska F, Nagy NV, Hoffmann E, Kortvelyesi T, Gajda T.	J Inorg Biochem	10.1016/j.jinorgbio.2011.09.029	2012
	Environmental Risk Factors Influence the Frequency of Coughing and Sneezing Episodes in Finisher Pigs on a Farm Free of Respiratory Disease.	Pessoa J, Camp Montoro J, Pina Nunes T, Norton T, McAloon C, Garcia Manzanilla E, Boyle L.	Animals (Basel)	10.3390/ani12080982	2022
Metabolism	Semiprocessive Hyperglycosylation of Adhesin by Bacterial Protein N-Glycosyltransferases.	Yakovlieva L, Ramirez-Palacios C, Marrink SJ, Walvoort MTC.	ACS Chem Biol	10.1021/acschembio.0c00848	2021
	A physiologically based pharmacokinetic model to optimize the dosage regimen and withdrawal time of cefquinome in pigs.	Mi K, Sun L, Hou Y, Cai X, Zhou K, Ma W, Xu X, Pan Y, Liu Z, Huang L.	PLoS Comput Biol	10.1371/journal.pcbi.1011331	2023
Metabolism	5-Lipoxygenase and cyclooxygenase-2 in the lungs of pigs naturally affected by enzootic pneumonia and porcine pleuropneumonia.	Giacominelli-Stuffler R, Marruchella G, Storelli MM, Sabatucci A, Angelucci CB, Maccarrone M.	Res Vet Sci	10.1016/j.rvsc.2012.01.013	2012
	A cross-sectional assessment of PRRSV nucleic acid detection by RT-qPCR in serum, ear-vein blood swabs, nasal swabs, and oral swabs from weaning-age pigs under field conditions.	Osemeke OH, Cezar GA, Paiva RC, Moraes DCA, Machado IF, Magalhaes ES, Poeta Silva APS, Mil-Homens M, Peng L, Jayaraman S, Trevisan G, Silva GS, Gauger PC, Linhares DCL.	Front Vet Sci	10.3389/fvets.2023.1200376	2023
	Training Convolutional Neural Networks to Score Pneumonia in Slaughtered Pigs.	Bonicelli L, Trachtman AR, Rosamilia A, Liuzzo G, Hattab J, Mira Alcaraz E, Del Negro E, Vincenzi S, Capobianco Dondona A, Calderara S, Marruchella G.	Animals (Basel)	10.3390/ani11113290	2021
	A tool to enhance antimicrobial stewardship using similarity networks to identify antimicrobial resistance patterns across farms.	Aguilar-Vega C, Scoglio C, Clavijo MJ, Robbins R, Karriker L, Liu X, Martinez-Lopez B.	Sci Rep	10.1038/s41598-023-29980-4	2023
Metabolism	Ohr, an in vivo-induced gene in Actinobacillus pleuropneumoniae, is located on a genomic island and requires glutathione-S-transferase for activity.	Wolfram TJ, Leveque RM, Kastenmayer RJ, Mulks MH.	FEMS Immunol Med Microbiol	10.1111/j.1574-695x.2009.00579.x	2009
Phylogeny	Bacterial pathogens associated with lung lesions in slaughter pigs from 125 herds.	Fablet C, Marois C, Dorenlor V, Eono F, Eveno E, Jolly JP, Le Devendec L, Kobisch M, Madec F, Rose N.	Res Vet Sci	10.1016/j.rvsc.2011.11.002	2012
	Copper Efflux System Required in Murine Lung Infection by Haemophilus influenzae Composed of a Canonical ATPase Gene and Tandem Chaperone Gene Copies.	Wong SM, Gawronski J, Akerley BJ.	Infect Immun	10.1128/iai.00091-23	2023
	Compositional analysis of the tonsil microbiota in relationship to Streptococcus suis disease in nursery pigs in Ontario.	Niazy M, Hill S, Nadeem K, Ricker N, Farzan A.	Anim Microbiome	10.1186/s42523-022-00162-3	2022
	Herd-level risk factors for chronic pleurisy in finishing pigs: a case-control study.	Halli O, Haimi-Hakala M, Oliviero C, Heinonen M.	Porcine Health Manag	10.1186/s40813-020-00156-0	2020
	ICEApl1, an Integrative Conjugative Element Related to ICEHin1056, Identified in the Pig Pathogen Actinobacillus pleuropneumoniae.	Bosse JT, Li Y, Fernandez Crespo R, Chaudhuri RR, Rogers J, Holden MT, Maskell DJ, Tucker AW, Wren BW, Rycroft AN, Langford PR, the BRaDP1T Consortium.	Front Microbiol	10.3389/fmicb.2016.00810	2016
Pathogenicity	[Interaction between Actinobacillus pleuropneumoniae RTX toxin and host--a review].	Fan S, Liu H, Chen Y, Chen H, He Q.	Wei Sheng Wu Xue Bao		2009
	Insights into the bacterial transferrin receptor: the structure of transferrin-binding protein B from Actinobacillus pleuropneumoniae.	Moraes TF, Yu RH, Strynadka NC, Schryvers AB.	Mol Cell	10.1016/j.molcel.2009.06.029	2009
Pathogenicity	Molecular characterization of enrofloxacin resistant Actinobacillus pleuropneumoniae isolates.	Wang YC, Chan JP, Yeh KS, Chang CC, Hsuan SL, Hsieh YM, Chang YC, Lai TC, Lin WH, Chen TH.	Vet Microbiol	10.1016/j.vetmic.2009.09.067	2010
Pathogenicity	Proteomic methods for the study of porcine acute phase proteins - anything new to detect?	Miller I, Gianazza E.	Vet Res Commun	10.1007/s11259-023-10170-6	2023
	Identification of the effect of N-glycan modification and its sialylation on proteolytic stability and glucose-stabilizing activity of glucagon-like peptide 1 by site-directed enzymatic glycosylation.	Liu H, Liang Z, Wang Y, Li Y, Wang Y, Guo X, Guan W, Zou W, Wu Z.	RSC Adv	10.1039/d2ra05872c	2022
	Natural competence in strains of Actinobacillus pleuropneumoniae.	Bosse JT, Sinha S, Schippers T, Kroll JS, Redfield RJ, Langford PR.	FEMS Microbiol Lett	10.1111/j.1574-6968.2009.01706.x	2009
	Glaesserella parasuis serotype 4 HPS4-YC disrupts the integrity of the swine tracheal epithelial barrier and facilitates bacterial translocation.	Wang Q, Chang X, Liu M, Lu Q, Zhu M, Lin H, Fan H.	Vet Res	10.1186/s13567-021-01005-w	2021
	Positive role for rApxIVN in the immune protection of pigs against infection by Actinobacillus pleuropneumoniae.	Wang C, Wang Y, Shao M, Si W, Liu H, Chang Y, Peng W, Kong X, Liu S.	Vaccine	10.1016/j.vaccine.2009.07.065	2009
Genetics	Characterization of Haemophilus Parasuis Serovar 2 CL120103, a Moderately Virulent Strain in China.	Che Y, Wang L, Wu X, Chen R, Wang C, Zhou L.	Open Life Sci	10.1515/biol-2018-0026	2018
	Structural and functional insights into iron acquisition from lactoferrin and transferrin in Gram-negative bacterial pathogens.	Chan C, Ng D, Fraser ME, Schryvers AB.	Biometals	10.1007/s10534-022-00466-6	2023
	Efficacy of a one-shot marbofloxacin treatment on acute pleuropneumonia after experimental aerosol inoculation of nursery pigs.	Hoeltig D, Rohde J, Brunner B, Hellmann K, Grandemange E, Waldmann KH.	Porcine Health Manag	10.1186/s40813-018-0089-2	2018
	Immunogenicity and protective efficacy of ApxIA and ApxIIA DNA vaccine against Actinobacillus pleuropneumoniae lethal challenge in murine model.	Chiang CH, Huang WF, Huang LP, Lin SF, Yang WJ.	Vaccine	10.1016/j.vaccine.2009.05.058	2009
Transcriptome	Evaluating anti-viral effect of Tylvalosin tartrate on porcine reproductive and respiratory syndrome virus and analyzing the related gene regulation by transcriptomics.	Tang X, Wang C, Sun W, Wu W, Sun S, Wan J, Zhu G, Ma N, Ma X, Xu R, Yang Q, Dai Y, Zhou L.	Virol J	10.1186/s12985-023-02043-w	2023
	Pyridoxal 5'-phosphate synthesis and salvage in Bacteria and Archaea: predicting pathway variant distributions and holes.	Denise R, Babor J, Gerlt JA, de Crecy-Lagard V.	Microb Genom	10.1099/mgen.0.000926	2023
	Toward a Method for Harmonized Susceptibility Testing of Mycoplasma bovis by Broth Microdilution.	Gutgemann F, Muller A, Churin Y, Kumm F, Braun AS, Yue M, Eisenberg T, Entorf M, Peters T, Kehrenberg C.	J Clin Microbiol	10.1128/jcm.01905-22	2023
	Multifocal granulomatous hepatitis caused by Actinobacillus pleuropneumoniae serotype 2 in slaughter pigs.	Ohba T, Shibahara T, Kobayashi H, Takashima A, Nagoshi M, Osanai R, Kubo M.	J Comp Pathol	10.1016/j.jcpa.2008.04.003	2008
	AasP autotransporter protein of Actinobacillus pleuropneumoniae does not protect pigs against homologous challenge.	Oldfield NJ, Worrall KE, Rycroft AN, Ali T, Wooldridge KG, Ala'Aldeen DA.	Vaccine	10.1016/j.vaccine.2009.06.047	2009
	Effect of enriched housing on levels of natural (auto-)antibodies in pigs co-infected with porcine reproductive and respiratory syndrome virus (PRRSV) and Actinobacillus pleuropneumoniae.	Luo L, van Dixhoorn IDE, Reimert I, Kemp B, Bolhuis JE, Parmentier HK.	Vet Res	10.1186/s13567-017-0481-y	2017
Metabolism	An isogenic Actinobacillus pleuropneumoniae AasP mutant exhibits altered biofilm formation but retains virulence.	Tegetmeyer HE, Fricke K, Baltes N.	Vet Microbiol	10.1016/j.vetmic.2009.01.026	2009
Pathogenicity	Structural Basis of Ca²⁺-Dependent Self-Processing Activity of Repeat-in-Toxin Proteins.	Kuban V, Macek P, Hritz J, Nechvatalova K, Nedbalcova K, Faldyna M, Sebo P, Zidek L, Bumba L.	mBio	10.1128/mbio.00226-20	2020
Pathogenicity	Prediction of marbofloxacin dosage for the pig pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida by pharmacokinetic/pharmacodynamic modelling.	Dorey L, Pelligand L, Lees P.	BMC Vet Res	10.1186/s12917-017-1128-y	2017
Enzymology	The influence of the site of drug administration on florfenicol pharmacokinetics in turkeys.	Bello A, Pozniak B, Smutkiewicz A, Switala M.	Poult Sci	10.1016/j.psj.2021.101536	2022
	Identification of Glaesserella parasuis and Differentiation of Its 15 Serovars Using High-Resolution Melting Assays.	Scherrer S, Rademacher F, Stephan R, Peterhans S.	Pathogens	10.3390/pathogens11070752	2022
	Serological patterns of Actinobacillus pleuropneumoniae, Mycoplasma hyopneumoniae, Pasteurella multocida and Streptococcus suis in pig herds affected by pleuritis.	Wallgren P, Norregard E, Molander B, Persson M, Ehlorsson CJ.	Acta Vet Scand	10.1186/s13028-016-0252-1	2016
	Hepatic gene expression changes in pigs experimentally infected with the lung pathogen Actinobacillus pleuropneumoniae as analysed with an innate immunity focused microarray.	Skovgaard K, Mortensen S, Boye M, Hedegaard J, Heegaard PM.	Innate Immun	10.1177/1753425909342730	2010
	Molecular pathogenesis of Haemophilus ducreyi infection in human volunteers.	Spinola SM, Fortney KR, Ofner S, Gebregziabher N, Brothwell JA, Katz BP.	Microbiol Mol Biol Rev	10.1128/mmbr.00055-24	2025
Pathogenicity	Decontamination of aerosolised bacteria from a pig farm environment using a pH neutral electrochemically activated solution (Ecas4 anolyte).	Tenzin S, Ogunniyi AD, Khazandi M, Ferro S, Bartsch J, Crabb S, Abraham S, Deo P, Trott DJ.	PLoS One	10.1371/journal.pone.0222765	2019
	The SapA Protein Is Involved in Resistance to Antimicrobial Peptide PR-39 and Virulence of Actinobacillus pleuropneumoniae.	Xie F, Wang Y, Li G, Liu S, Cui N, Liu S, Langford PR, Wang C.	Front Microbiol	10.3389/fmicb.2017.00811	2017
	Identifying effective surveillance measures for swine pathogens using contact networks and mathematical modeling.	Moriarty K, Champetier A, Galli F, Durr S, Chitnis N.	PLoS One	10.1371/journal.pone.0329714	2025
	A cross-sectional study of risk factors associated with pulmonary lesions in pigs at slaughter.	Meyns T, Van Steelant J, Rolly E, Dewulf J, Haesebrouck F, Maes D.	Vet J	10.1016/j.tvjl.2009.12.027	2011
	The N-linking glycosylation system from Actinobacillus pleuropneumoniae is required for adhesion and has potential use in glycoengineering.	Cuccui J, Terra VS, Bosse JT, Naegeli A, Abouelhadid S, Li Y, Lin CW, Vohra P, Tucker AW, Rycroft AN, Maskell DJ, Aebi M, Langford PR, Wren BW, BRaDP1T Consortium.	Open Biol	10.1098/rsob.160212	2017
	Characterization of a recombinant transferrin-binding protein A (TbpA) fragment from Haemophilus parasuis serovar 5.	Martinez S, Frandoloso R, Rodriguez-Ferri EF, Gonzalez-Zorn B, Gutierrez-Martin CB.	FEMS Microbiol Lett	10.1111/j.1574-6968.2010.01970.x	2010
	Structural analyses of the core oligosaccharide from the lipopolysaccharide of bovine and ovine strains of Mannheimia haemolytica serotype 2.	St Michael F, Vinogradov E, Cox AD.	Carbohydr Res	10.1016/j.carres.2011.05.001	2011
Pathogenicity	Application of enrofloxacin and orbifloxacin disks approved in Japan for susceptibility testing of representative veterinary respiratory pathogens.	Harada K, Usui M, Asai T.	J Vet Med Sci	10.1292/jvms.14-0266	2014
Enzymology	Multi-organ spreading of Actinobacillus pleuropneumoniae serovar 7 in weaned pigs during the first week after experimental infection.	Hoeltig D, Rohde J, Frase R, Nietfeld F, Waldmann KH, Valentin-Weigand P, Meens J.	Vet Res	10.1186/s13567-018-0592-0	2018
	Comparison of different doses of antigen for intradermal administration in pigs: the Actinobacillus pleuropneumoniae model.	Bernardy J, Nechvatalova K, Krejci J, Kudlackova H, Brazdova I, Kucerova Z, Faldyna M.	Vaccine	10.1016/j.vaccine.2008.09.027	2008
	A TolC-Like Protein of Actinobacillus pleuropneumoniae Is Involved in Antibiotic Resistance and Biofilm Formation.	Li Y, Cao S, Zhang L, Lau GW, Wen Y, Wu R, Zhao Q, Huang X, Yan Q, Huang Y, Wen X.	Front Microbiol	10.3389/fmicb.2016.01618	2016
	SARS-CoV-2 Infection Causes Heightened Disease Severity and Mortality in a Mouse Model of Down Syndrome.	Pechous RD, Malaviarachchi PA, Xing Z, Douglas A, Crane SD, Theriot HM, Zhang Z, Ghaffarieh A, Huang L, Yu YE, Zhang X.	Biomedicines	10.3390/biomedicines12030543	2024
	Identification and characterization of serovar-independent immunogens in Actinobacillus pleuropneumoniae.	Antenucci F, Fougeroux C, Bosse JT, Magnowska Z, Roesch C, Langford P, Holst PJ, Bojesen AM.	Vet Res	10.1186/s13567-017-0479-5	2017
Metabolism	In vivo induced RTX toxin ApxIVA is essential for the full virulence of Actinobacillus pleuropneumoniae.	Liu J, Chen X, Tan C, Guo Y, Chen Y, Fu S, Bei W, Chen H.	Vet Microbiol	10.1016/j.vetmic.2009.01.011	2009
	Analysis of an Actinobacillus pleuropneumoniae multi-resistance plasmid, pHB0503.	Kang M, Zhou R, Liu L, Langford PR, Chen H.	Plasmid	10.1016/j.plasmid.2008.11.001	2009
	Recent trends in antimicrobial susceptibility and the presence of the tetracycline resistance gene in Actinobacillus pleuropneumoniae isolates in Japan.	Morioka A, Asai T, Nitta H, Yamamoto K, Ogikubo Y, Takahashi T, Suzuki S.	J Vet Med Sci	10.1292/jvms.70.1261	2008
Phylogeny	Novel reassortant of H1N1 swine influenza virus detected in pig population in Russia.	Sobolev I, Kurskaya O, Leonov S, Kabilov M, Alikina T, Alekseev A, Yushkov Y, Saito T, Uchida Y, Mine J, Shestopalov A, Sharshov K.	Emerg Microbes Infect	10.1080/22221751.2019.1673136	2019
Metabolism	Glycoprotein analysis of porcine bronchoalveolar lavage fluid reveals potential biomarkers corresponding to resistance to Actinobacillus pleuropneumoniae infection.	Kahlisch D, Buettner FF, Naim HY, Gerlach GF, FUGATO-consortium IRAS.	Vet Res	10.1051/vetres/2009043	2009
	Defining the scope of the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet): a bottom-up and One Health approach.	Mader R, EU-JAMRAI, Bourely C, Amat JP, Broens EM, Busani L, Callens B, Crespo-Robledo P, Damborg P, Filippitzi ME, Fitzgerald W, Gronthal T, Haenni M, Heuvelink A, van Hout J, Kaspar H, Munoz Madero C, Norstrom M, Pedersen K, Pokludova L, Dal Pozzo F, Slowey R, Urdahl AM, Vatopoulos A, Zafeiridis C, Madec JY.	J Antimicrob Chemother	10.1093/jac/dkab462	2022
Metabolism	The staphylococcal nuclease prevents biofilm formation in Staphylococcus aureus and other biofilm-forming bacteria.	Tang J, Kang M, Chen H, Shi X, Zhou R, Chen J, Du Y.	Sci China Life Sci	10.1007/s11427-011-4195-5	2011
	Pleuritis in slaughter pigs: relations between lung lesions and bacteriology in 10 herds with high pleuritis.	Jirawattanapong P, Stockhofe-Zurwieden N, van Leengoed L, Wisselink H, Raymakers R, Cruijsen T, van der Peet-Schwering C, Nielen M, van Nes A.	Res Vet Sci	10.1016/j.rvsc.2009.06.007	2010
	Pathogen exposure influences immune parameters around weaning in pigs reared in commercial farms.	Herve J, Haurogne K, Buchet A, Bacou E, Mignot G, Allard M, Leblanc-Maridor M, Gavaud S, Lehebel A, Terenina E, Mormede P, Merlot E, Belloc C, Bach JM, Lieubeau B.	BMC Immunol	10.1186/s12865-022-00534-z	2022
Transcriptome	Pathological observation and transcriptomic analysis of thymus injury in PRRSV-infected piglets.	Su N, Lin Z, Liu X, Sun X, Jin X, Feng H, Zhan C, Hu X, Gu C, Zhang W, Cheng G.	Vet Res Commun	10.1007/s11259-023-10133-x	2023
	Genomic and transcriptomic insights into complex virus-prokaryote interactions in marine biofilms.	Zhou K, Wong TY, Long L, Anantharaman K, Zhang W, Wong WC, Zhang R, Qian PY.	ISME J	10.1038/s41396-023-01546-2	2023
Transcriptome	Transcriptome Analysis of Selenium-Treated Porcine Alveolar Macrophages Against Lipopolysaccharide Infection.	Liu JX, Chao XY, Chen P, Wang YD, Su TJ, Li M, Xu RY, Wu Q.	Front Genet	10.3389/fgene.2021.645401	2021
	Vaccination with an Escherichia coli F4/F18 Vaccine Improves Piglet Performance Combined with a Reduction in Antimicrobial Use and Secondary Infections Due to Streptococcus suis.	Vangroenweghe FACJ, Boone M.	Animals (Basel)	10.3390/ani12172231	2022
Pathogenicity	Pharmacokinetic/pharmacodynamic integration and modelling of florfenicol for the pig pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida.	Dorey L, Pelligand L, Cheng Z, Lees P.	PLoS One	10.1371/journal.pone.0177568	2017
	Etiology of acute respiratory disease in fattening pigs in Finland.	Haimi-Hakala M, Halli O, Laurila T, Raunio-Saarnisto M, Nokireki T, Laine T, Nykasenoja S, Pelkola K, Segales J, Sibila M, Oliviero C, Peltoniemi O, Pelkonen S, Heinonen M.	Porcine Health Manag	10.1186/s40813-017-0065-2	2017
Genetics	Recommendation of a standardized broth microdilution method for antimicrobial susceptibility testing of Avibacterium paragallinarum and resistance monitoring.	Gutgemann F, Heuvelink A, Muller A, Churin Y, Buter R, Jung A, Feberwee A, Wiegel J, Kumm F, Braun AS, Yue M, Soriano-Vargas E, Swanepoel S, Botteldoorn N, Kirchner M, Kehrenberg C.	J Clin Microbiol	10.1128/jcm.01011-23	2024
	Status and gaps of research on respiratory disease pathogens of swine in Africa.	Oba P, Wieland B, Mwiine FN, Erume J, Gertzell E, Jacobson M, Dione MM.	Porcine Health Manag	10.1186/s40813-020-0144-7	2020
	Histone-like protein H-NS regulates biofilm formation and virulence of Actinobacillus pleuropneumoniae.	Dalai B, Zhou R, Wan Y, Kang M, Li L, Li T, Zhang S, Chen H.	Microb Pathog	10.1016/j.micpath.2008.11.005	2009
	Long-term follow-up of Mycoplasma hyopneumoniae-specific immunity in vaccinated pigs.	Biebaut E, Beuckelaere L, Boyen F, Haesebrouck F, Gomez-Duran CO, Devriendt B, Maes D.	Vet Res	10.1186/s13567-023-01145-1	2023
	[cDNA library constructing and specific antigen expression of Streptomyces thermohydroscopicus].	Xu L, Wang LL, Liu S, Ling Y, Ma L, Wang Q, Zhang LJ, He XY, Zhao MJ, Wang XG.	Zhonghua Jie He He Hu Xi Za Zhi		2012
	Analysis of the Actinobacillus pleuropneumoniae HlyX (FNR) regulon and identification of iron-regulated protein B as an essential virulence factor.	Buettner FF, Bendalla IM, Bosse JT, Meens J, Nash JH, Hartig E, Langford PR, Gerlach GF.	Proteomics	10.1002/pmic.200800439	2009
	[Functional genome analysis investigating resistance to respiratory tract disease in a porcine Actinobacillus pleuropneumoniae infection model].	Rehm T, Benga L, Danilowicz E, Drungowski M, Hoeltig D, Kahlisch D, Oehlmann W, Probst I, Gerlach GF, IRAS-Konsortium beitragenden Wissenschaftler.	Dtsch Tierarztl Wochenschr		2008
	PK-PD integration of enrofloxacin and cefquinome alone and in combination against Klebsiella pneumoniae using an in vitro dynamic model.	Wei Y, Ji X, Zhang F, Zhang S, Deng Q, Ding H.	Front Pharmacol	10.3389/fphar.2023.1226936	2023
Transcriptome	Transcriptome analysis of heat resistance regulated by quorum sensing system in Glaesserella parasuis.	Zhang B, Jiang C, Cao H, Zeng W, Ren J, Hu Y, Li W, He Q.	Front Microbiol	10.3389/fmicb.2022.968460	2022
Phylogeny	Actinobacillus pleuropneumoniae serotype 10 derived ApxI induces apoptosis in porcine alveolar macrophages.	Chien MS, Chan YY, Chen ZW, Wu CM, Liao JW, Chen TH, Lee WC, Yeh KS, Hsuan SL.	Vet Microbiol	10.1016/j.vetmic.2008.09.071	2009
	Screening of strain-specific Actinobacillus pleuropneumoniae genes using a combination method.	Lei L, Du C, Yang P, Xie F, Ou P, Han W, Wang J.	J Microbiol Methods	10.1016/j.mimet.2009.01.015	2009
	Transposition mechanism of ISApl1-the determinant of colistin resistance dissemination.	Li W, He Z, Di W, Xu W, Li Y, Sun B.	Antimicrob Agents Chemother	10.1128/aac.01231-23	2024
	A competence-regulated toxin-antitoxin system in Haemophilus influenzae.	Findlay Black H, Mastromatteo S, Sinha S, Ehrlich RL, Nislow C, Chang Mell J, Redfield RJ.	PLoS One	10.1371/journal.pone.0217255	2020
Metabolism	The effect of ArcA on the growth, motility, biofilm formation, and virulence of Plesiomonas shigelloides.	Yan J, Li Y, Guo X, Wang X, Liu F, Li A, Cao B.	BMC Microbiol	10.1186/s12866-021-02322-y	2021
	[Comparison of the diagnostic significance of clinical, radiographic and ultrasonographic results after an experimental aerosol infection of pigs with Actinobacillus pleuropneumoniae].	Holtig D, Hennig-Pauka I, Beyerbach M, Thies K, Rehm T, Gerlach GF, Waldmann KH, FUGATO-Konsortiums IRAS.	Berl Munch Tierarztl Wochenschr		2008
Enzymology	Pharmacokinetics of Tildipirosin in Plasma, Milk, and Somatic Cells Following Intravenous, Intramuscular, and Subcutaneous Administration in Dairy Goats.	Galecio JS, Marin P, Hernandis V, Botia M, Escudero E.	Pharmaceutics	10.3390/pharmaceutics14040860	2022
	[Cloning and expression of hemolytic-toxin from Actinobacillus pleuropneumoniae and the immunoprotection in mice].	Du A, Diao Y, Zhang W, Zhang R, Zang D, Liu F.	Wei Sheng Wu Xue Bao		2008
	Serological responses to two serovar-independent ELISA antigens of Actinobacillus pleuropneumoniae in Australian commercial pig herds.	Eamens GJ, Gonsalves JR, Whittington AM, Turner B.	Aust Vet J	10.1111/j.1751-0813.2008.00368.x	2008
	Identification of Actinobacillus pleuropneumoniae biovars 1 and 2 in pigs using a PCR assay.	Serrano-Rubio LE, Tenorio-Gutierrez V, Suarez-Guemes F, Reyes-Cortes R, Rodriguez-Mendiola M, Arias-Castro C, Godinez-Vargas D, de la Garza M.	Mol Cell Probes	10.1016/j.mcp.2008.09.001	2008
	Experimental infection of SPF pigs with Actinobacillus pleuropneumoniae serotype 9 alone or in association with Mycoplasma hyopneumoniae.	Marois C, Gottschalk M, Morvan H, Fablet C, Madec F, Kobisch M.	Vet Microbiol	10.1016/j.vetmic.2008.09.061	2009
	Characterization of ISApl1, an insertion element identified from Actinobacillus pleuropneumoniae field isolate in China.	Liu J, Tan C, Li J, Chen H, Xu P, He Q, Bei W, Chen H.	Vet Microbiol	10.1016/j.vetmic.2008.05.031	2008
	Actinobacillus pleuropneumoniae vaccines: from bacterins to new insights into vaccination strategies.	Ramjeet M, Deslandes V, Goure J, Jacques M.	Anim Health Res Rev	10.1017/s1466252307001338	2008
	Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration.	Cao Q, Wei W, Wang H, Wang Z, Lv Y, Dai M, Tan C, Chen H, Wang X.	Virulence	10.1080/21505594.2021.1966996	2021
	[Study of the virulence of Actinobacillus pleuropneumoniae in finishing pigs as a basis for vaccination development].	Hennig-Pauka I, Baltes N, Jacobsen I, Stratmann-Selke J, Gerlach GF, Selbitz HJ, Waldmann KH.	Berl Munch Tierarztl Wochenschr		2008
	Gold(III) enhanced chemiluminescence immunoassay for detection of antibody against ApxIV of Actinobacillus pleuropneumoniae.	Hu D, Han H, Zhou R, Dong F, Bei W, Jia F, Chen H.	Analyst	10.1039/b715476c	2008
Pathogenicity	Evaluation of multicomponent recombinant vaccines against Actinobacillus pleuropneumoniae in mice.	Shao M, Wang Y, Wang C, Guo Y, Peng Y, Liu J, Li G, Liu H, Liu S	Acta Vet Scand	10.1186/1751-0147-52-52	2010
Metabolism	Characterization of apxIVA, a new RTX determinant of Actinobacillus pleuropneumoniae.	Schaller A, Kuhn R, Kuhnert P, Nicolet J, Anderson TJ, Maclnnes JI, Segers RPAM, Frey J	Microbiology (Reading)	10.1099/13500872-145-8-2105	1999
Metabolism	First chromosomal restriction map of Actinobacillus pleuropneumoniae and localization of putative virulence-associated genes.	Oswald W, Konine DV, Rohde J, Gerlach GF	J Bacteriol	10.1128/JB.181.14.4161-4169.1999	1999
Phylogeny	Characterization of monoclonal antibodies that recognize common epitopes located on O antigen of lipopolysaccharide of serotypes 1, 9 and 11 of Actinobacillus pleuropneumoniae.	Rodriguez Barbosa JI, Gutierrez Martin CB, Tascon RI, Gonzalez OR, Mittal KR, Rodriguez Ferri EF	FEMS Immunol Med Microbiol	10.1111/j.1574-695X.1996.tb00134.x	1996
Phylogeny	Comparative study of iron acquisition by biotype 1 and biotype 2 strains of Actinobacillus pleuropneumoniae.	D'Silva CG, Archibald FS, Niven DF	Vet Microbiol	10.1016/0378-1135(94)00109-a	1995
Phylogeny	Efficacy of florfenicol on experimental Actinobacillus pleuropneumonia in pigs.	Ueda Y, Ohtsuki S, Narukawa N	J Vet Med Sci	10.1292/jvms.57.261	1995
Enzymology	Lipopolysaccharides of Actinobacillus pleuropneumoniae (serotype 1): a readily obtainable antigen for ELISA serodiagnosis of pig pleuropneumonia.	Radacovici S, Gottschalk M, Dubreuil JD	Vet Microbiol	10.1016/0378-1135(94)90159-7	1994
Enzymology	Antigenic differences within Actinobacillus pleuropneumoniae serotype 1.	Jolie RA, Mulks MH, Thacker BJ	Vet Microbiol	10.1016/0378-1135(94)90151-1	1994
Enzymology	Clonal analysis of the Actinobacillus pleuropneumoniae population in a geographically restricted area by multilocus enzyme electrophoresis.	Moller K, Nielsen R, Andersen LV, Kilian M	J Clin Microbiol	10.1128/jcm.30.3.623-627.1992	1992
Metabolism	Calcium binds to and is required for biological activity of the 104-kilodalton hemolysin produced by Actinobacillus pleuropneumoniae serotype 1.	Devenish J, Rosendal S	Can J Microbiol	10.1139/m91-050	1991
	Passive protection of piglets by monoclonal antibodies against experimental infection with Actinobacillus pleuropneumoniae.	Smith IK, Lida J	Res Vet Sci		1990
Phylogeny	Structural studies of the capsular polysaccharide from Haemophilus pleuropneumoniae serotype 1.	Altman E, Brisson JR, Perry MB	Biochem Cell Biol	10.1139/o86-097	1986
Phylogeny	Comparative virulence of porcine Haemophilus bacteria.	Rosendal S, Boyd DA, Gilbride KA	Can J Comp Med		1985
Phylogeny	Haemophilus pleuropneumoniae serotyping.	Rosendal S, Boyd DA	J Clin Microbiol	10.1128/jcm.16.5.840-843.1982	1982

References

#5054	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 13472
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#39724	; Curators of the CIP;
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#68371	Automatically annotated from API 50CH acid .
#68377	Automatically annotated from API NH .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#121870	Collection of Institut Pasteur ; Curators of the CIP; CIP 100916
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Haemophilus pleuropneumoniae (DSM 13472, ATCC 27088, CCM 5869)

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